GWAS1442975_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1442975_H (atopic eczema QTL GWAS1442975 (human)) Homo sapiens

Symbol: GWAS1442975_H
Name: atopic eczema QTL GWAS1442975 (human)
RGD ID: 597346901
Trait: atopic eczema
LOD Score: Not Available
P Value: 4E-95
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381611,135,732 - 11,135,733RGD_MAPPER_PIPELINEGRCh38
GRCh371611,229,589 - 11,229,590RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1442975_HHumanatopic dermatitis  IAGPrs2041733405850206 GWAS_CATALOGPMID:37794016

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1442975_HHumanAtopic dermatitis  IAGPrs2041733405850206 GWAS_CATALOGPMID:37794016
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1442975_HHumanatopic eczema  IAGPrs2041733405850206 GWAS_CATALOGPMID:37794016

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1604037CLEC16AC-type lectin domain containing 16A161094456411182186Human


Peak: (rs2041733)
Human AssemblyChrPosition (strand)Source
GRCh381611,135,732 - 11,135,733RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597076230GWAS1172304_Hatopic eczema QTL GWAS1172304 (human)3e-11atopic eczema161113573211135733Human
597086934GWAS1183008_Hallergic disease, age at onset QTL GWAS1183008 (human)2e-13allergic disease, age at onset161113573211135733Human
597086950GWAS1183024_Hatopic eczema QTL GWAS1183024 (human)3e-15atopic eczema161113573211135733Human
597116870GWAS1212944_Hatopic eczema QTL GWAS1212944 (human)2e-20atopic eczema161113573211135733Human
597349759GWAS1445833_Hatopic eczema QTL GWAS1445833 (human)1e-22atopic eczema161113573211135733Human
597240487GWAS1336561_HEczematoid dermatitis QTL GWAS1336561 (human)8e-22Eczematoid dermatitis161113573211135733Human
597346901GWAS1442975_Hatopic eczema QTL GWAS1442975 (human)4e-95atopic eczema161113573211135733Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1442975_H GCST90244787 Atopic dermatitis 60,653 European ancestry cases, 804,329 European ancestry controls C 0.54 4E-95 94.398 rs2041733 0.94 atopic eczema (EFO:0000274)
 PMID:37794016
GWAS1172304_H GCST003184 Atopic dermatitis 18,900 European ancestry cases, 1,472 Japanese ancestry cases, 422 African American cases, 300 Latino cases, 305 cases, 84,166 European ancestry controls, 7,966 Japanese ancestry controls, 844 African American controls, 1,592 Latino controls, 896 controls T NR 3E-11 10.523 rs2041733 1.08 atopic eczema (EFO:0000274)
 PMID:26482879
GWAS1183008_H GCST010985 Allergic disease (asthma, hay fever and/or eczema) (age of onset) 117,130 European ancestry individuals T 0.447 2E-13 12.699 rs2041733 0.031 age at onset (EFO:0004847)
 PMID:32603359
GWAS1183024_H GCST010090 Atopic dermatitis 2,425 European ancestry cases, 5,449 European ancestry controls A 0.4528 3E-15 14.523 rs2041733 1.23 atopic eczema (EFO:0000274)
 PMID:23727859
None Available GCST010984 Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) 477,968 European ancestry individuals T 0.447 2E-13 12.699 rs2041733 0.031 PMID:32603359
GWAS1212944_H GCST90086149 Atopic dermatitis 2,597 Japanese ancestry cases, 110,504 Japanese ancestry controls, 25,685 European ancestry cases, 76,768 European ancestry controls ? NR 2E-20 19.699 rs2041733 0.91 atopic eczema (EFO:0000274)
 PMID:34116867
GWAS1336561_H GCST90044763 Eczema 20,016 European ancestry cases, 380,433 European ancestry controls C 0.5358 8E-22 21.097 rs2041733 0.9 Eczematoid dermatitis (HP:0000964)
 PMID:34785669
GWAS1445833_H GCST90297795 Atopic dermatitis 35,156 European ancestry cases, 846,868 European ancestry controls, 2,385 Japanese ancestry cases, 209,651 Japanese ancestry controls T NR 1E-22 22 rs2041733 0.0789 atopic eczema (EFO:0000274)
 PMID:38663478
Database
Acc Id
Source(s)
GWAS Catalog GCST90244787 GWAS Catalog

Note Type Note Reference