GWAS604019_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS604019_H (eosinophil count QTL GWAS604019 (human)) Homo sapiens

Symbol: GWAS604019_H
Name: eosinophil count QTL GWAS604019 (human)
RGD ID: 406955043
Trait: eosinophil quantity   (VT:0002602)    
Measurement Type: blood eosinophil count   (CMO:0000033)    
LOD Score: Not Available
P Value: 5.0E-38
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381611,116,590 - 11,116,591RGD_MAPPER_PIPELINEGRCh38
GRCh371611,210,447 - 11,210,448RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS604019_HHumanblood eosinophil count  IAGPrs12935413405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS604019_HHumaneosinophil quantity  IAGPrs12935413405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS604019_HHumaneosinophil count  IAGPrs12935413405850206 GWAS_CATALOGPMID:27863252

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1604037CLEC16AC-type lectin domain containing 16A161094456411182186Human


Peak: (rs12935413)
Human AssemblyChrPosition (strand)Source
GRCh381611,116,590 - 11,116,591RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
406955043GWAS604019_Heosinophil count QTL GWAS604019 (human)5e-38eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)161111659011116591Human
597599275GWAS1656135_Hbasophil measurement QTL GWAS1656135 (human)7e-13basophil measurement161111659011116591Human
406967271GWAS616247_Hbasophil count, eosinophil count QTL GWAS616247 (human)6e-39eosinophil quantity (VT:0002602)blood granulocyte count (CMO:0000111)161111659011116591Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS604019_H GCST004606 Eosinophil counts 172,275 European ancestry individuals A 0.3529 5E-38 37.302 rs12935413 0.04820378 eosinophil count (EFO:0004842)
 PMID:27863252
GWAS616247_H GCST004624 Sum eosinophil basophil counts 171,771 European ancestry individuals A 0.3529 6E-39 38.222 rs12935413 0.04884417 basophil count (EFO:0005090)
eosinophil count (EFO:0004842)
 PMID:27863252
GWAS1656135_H GCST90479513 Basophil (absolute count, mean, inv-norm transformed) 45,900 African American or Afro-Caribbean individuals, 20,397 Hispanic or Latin American individuals, 2,442 East Asian ancestry individuals, 158,583 European ancestry individuals G 0.6607 7E-13 12.155 rs12935413 0.02568 basophil measurement (EFO:0803539)
 PMID:39024449
Database
Acc Id
Source(s)
GWAS Catalog GCST004606 GWAS Catalog

Note Type Note Reference