GWAS1322537_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1322537_H (asthma, age at onset QTL GWAS1322537 (human)) Homo sapiens

Symbol: GWAS1322537_H
Name: asthma, age at onset QTL GWAS1322537 (human)
RGD ID: 597226463
Trait: asthma, age at onset
LOD Score: Not Available
P Value: 4.0E-7
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381611,119,164 - 11,119,165RGD_MAPPER_PIPELINEGRCh38
GRCh371611,213,021 - 11,213,022RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1322537_HHumanasthma  IAGPrs35441874405850206Based on the MONDO term ID from GWASGWAS_CATALOGPMID:30929738

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1322537_HHumanage at onset  IAGPrs35441874405850206 GWAS_CATALOGPMID:30929738

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1604037CLEC16AC-type lectin domain containing 16A161094456411182186Human


Peak: (rs35441874)
Human AssemblyChrPosition (strand)Source
GRCh381611,119,164 - 11,119,165RGD_MAPPER_PIPELINE


1 to 10 of 17 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597110546GWAS1206620_HInhalant adrenergic use measurement QTL GWAS1206620 (human)9e-16childhood onset asthma161111916411119165Human
597226463GWAS1322537_Hasthma, age at onset QTL GWAS1322537 (human)0.0000004asthma, age at onset161111916411119165Human
407278222GWAS927198_Hasthma QTL GWAS927198 (human)1e-30asthma161111916411119165Human
597078782GWAS1174856_Hadult onset asthma QTL GWAS1174856 (human)3e-15adult onset asthma161111916411119165Human
597099231GWAS1195305_Hneutrophil percentage of leukocytes QTL GWAS1195305 (human)3e-11neutrophil quantity (VT:0000222)blood neutrophil count to total leukocyte count ratio (CMO:0000370)161111916411119165Human
597227122GWAS1323196_Hasthma QTL GWAS1323196 (human)4e-34asthma161111916411119165Human
597247541GWAS1343615_Hasthma QTL GWAS1343615 (human)2e-27asthma161111916411119165Human
597341814GWAS1437888_Hasthma QTL GWAS1437888 (human)2e-37asthma161111916411119165Human
597061083GWAS1157157_HEczematoid dermatitis QTL GWAS1157157 (human)1e-44Eczematoid dermatitis161111916411119165Human
597217590GWAS1313664_Hadult onset asthma QTL GWAS1313664 (human)1e-19adult onset asthma161111916411119165Human

1 to 10 of 17 rows


1 to 18 of 18 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1322537_H GCST007797 Asthma onset (childhood vs adult) 13,962 European ancestry childhood onset cases, 14,873 European ancestry adult onset cases T 0.748 4E-7 6.398 rs35441874 1.06 age at onset (EFO:0004847)
 PMID:30929738
GWAS1157157_H GCST007075 Eczema approximately 459,000 European ancestry individuals ? NR 1E-44 44 rs35441874 N/A Eczematoid dermatitis (HP:0000964)
 PMID:30595370
GWAS1174856_H GCST009842 Asthma (adult onset) 33,418 European ancestry cases, 393,186 European ancestry controls ? NR 3E-15 14.523 rs35441874 N/A adult onset asthma (EFO:1002011)
 PMID:31669095
GWAS1195305_H GCST90002399 Neutrophil percentage of white cells 408,112 British individuals A 0.247641 3E-11 10.523 rs35441874 0.01714678 neutrophil percentage of leukocytes (EFO:0007990)
 PMID:32888494
GWAS1205912_H GCST007942 Medication use (glucocorticoids) 17,352 European ancestry cases, 188,348 European ancestry controls A 0.246038 4E-9 8.398 rs35441874 0.077133745 Glucocorticoid use measurement (EFO:0009942)
 PMID:31015401
GWAS1206620_H GCST007941 Medication use (adrenergics, inhalants) 28,880 European ancestry cases, 147,565 European ancestry controls A 0.244249 9E-16 15.046 rs35441874 0.08478937 Inhalant adrenergic use measurement (EFO:0009941)
 PMID:31015401
GWAS1240978_H GCST90255668 Age of onset of adult onset asthma 56,744 European ancestry cases, 674,014 European ancestry controls ? NR 3E-20 19.523 rs35441874 0.071081 age of onset of asthma (OBA:2001001)
 PMID:36778051
None Available GCST90018895 Pediatric asthma 27,712 European ancestry cases, 411,131 European ancestry controls, 547 East Asian ancestry cases, 161,803 East Asian ancestry controls A NR 9E-16 15.046 rs35441874 0.087 PMID:34594039
GWAS1300248_H GCST009798 Asthma 16,247 European ancestry cases, 346,486 European ancestry controls, 52,942 cases, 355,713 controls T 0.7529 2E-33 32.699 rs35441874 1.0940201 PMID:31959851
GWAS1313664_H GCST007799 Asthma (adult onset) 26,582 European ancestry cases, 300,671 European ancestry controls ? NR 1E-19 19 rs35441874 1.076 adult onset asthma (EFO:1002011)
 PMID:30929738
GWAS1323196_H GCST007798 Asthma 40,544 European ancestry cases, 300,671 European ancestry controls T NR 4E-34 33.398 rs35441874 1.1 PMID:30929738
GWAS901925_H GCST010042 Asthma 64,538 European ancestry cases, 239,321 European ancestry controls T 0.754202 7E-42 41.155 rs35441874 1.0995073 PMID:32296059
GWAS1343615_H GCST90014325 Asthma 56,167 White-British ancestry cases, 352,255 White-British ancestry controls A 0.247084124158008 2E-27 26.699 rs35441874 0.082469344 PMID:34103634
GWAS927198_H GCST008916 Asthma 46,802 European ancestry cases, 347,481 European ancestry controls T 0.75274 1E-30 30 rs35441874 1.0866435 PMID:31619474
GWAS1408341_H GCST90018999 Medication use (adrenergics, inhalants) 28,880 European ancestry cases, 147,565 European ancestry controls, 5,880 East Asian ancestry cases, 172,846 East Asian ancestry controls A NR 3E-16 15.523 rs35441874 0.0823 Inhalant adrenergic use measurement (EFO:0009941)
 PMID:34594039
GWAS1414131_H GCST90019000 Medication use (glucocorticoids) 17,352 European ancestry cases, 188,348 European ancestry controls, 13,102 East Asian ancestry cases, 165,624 East Asian ancestry controls A NR 1E-9 9 rs35441874 0.0688 Glucocorticoid use measurement (EFO:0009942)
 PMID:34594039
GWAS1429455_H GCST90244761 Asthma in any disease 44,383 European ancestry cases, 260,715 European ancestry controls A 0.247 1E-22 22 rs35441874 0.91943127 PMID:36344522
GWAS1437888_H GCST90399687 Asthma 139 Middle Eastern ancestry cases, 1,434 Middle Eastern ancestry controls, 4,069 Admixed American ancestry cases, 14,104 Admixed American ancestry controls, 4,015 South Asian ancestry cases, 27,091 South Asian ancestry controls, 5,051 African ancestry cases, 27,607 African ancestry controls, 18,549 East Asian ancestry cases, 322,655 East Asian ancestry controls, 121,940 European ancestry cases, 1,254,131 European ancestry controls A 0.205 2E-37 36.699 rs35441874 0.066501 PMID:36777996
1 to 18 of 18 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST007797 GWAS Catalog

Note Type Note Reference