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Gene: IL2RA (interleukin 2 receptor subunit alpha) Homo sapiens
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Symbol: IL2RA
Name: interleukin 2 receptor subunit alpha
Description: Contributes to interleukin-2 receptor activity. Involved in regulation of T cell tolerance induction. Predicted to localize to the interleukin-2 receptor complex. Implicated in lymphopenia; multiple sclerosis; primary immunodeficiency disease; type 1 diabetes mellitus; and type 1 diabetes mellitus 10. Biomarker of hemorrhagic fever with renal syndrome and idiopathic pulmonary fibrosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD25; IDDM10; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; IL2R; IMD41; insulin-dependent diabetes mellitus 10; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor subunit alpha; p55; TAC antigen; TCGFR
Orthologs:
Mus musculus (house mouse) : Il2ra (interleukin 2 receptor, alpha chain)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il2ra (interleukin 2 receptor subunit alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il2ra (interleukin 2 receptor subunit alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : IL2RA (interleukin 2 receptor subunit alpha)
Canis lupus familiaris (dog) : IL2RA (interleukin 2 receptor subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il2ra (interleukin 2 receptor subunit alpha)
Sus scrofa (pig) : IL2RA (interleukin 2 receptor subunit alpha)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38106,010,689 - 6,062,367 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37106,052,657 - 6,104,333 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36106,093,512 - 6,144,278 (-)NCBINCBI36hg18NCBI36
Build 34106,093,511 - 6,144,278NCBI
Celera105,982,579 - 6,033,743 (-)NCBI
Cytogenetic Map10p15.1NCBI
HuRef105,979,490 - 6,030,662 (-)NCBIHuRef
CHM1_1106,052,649 - 6,103,793 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IL2RA
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735947
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.