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Gene: HLA-DQA2 (major histocompatibility complex, class II, DQ alpha 2) Homo sapiens
Symbol: HLA-DQA2
Name: major histocompatibility complex, class II, DQ alpha 2
Description: Predicted to be involved in T cell receptor signaling pathway; antigen processing and presentation of exogenous peptide antigen via MHC class II; and interferon-gamma-mediated signaling pathway. Predicted to localize to bounding membrane of organelle; integral component of lumenal side of endoplasmic reticulum membrane; and plasma membrane. Implicated in asthma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DC-1 alpha chain; DC-alpha; DX alpha chain; DX-ALPHA; HLA class II histocompatibility antigen, DQ alpha 1 chain; HLA class II histocompatibility antigen, DQ alpha 2 chain; HLA class II histocompatibility antigen, DQ(6) alpha chain; HLA-DCA; HLA-DQA1; HLA-DXA; HLADQA2; MHC class II antigen; MHC class II DQA1; MHC class II DQA2
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl632,741,391 - 32,747,198 (+)EnsemblGRCh38hg38GRCh38
GRCh38632,741,391 - 32,747,198 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37632,709,156 - 32,714,664 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,817,141 - 32,823,199 (+)NCBINCBI36hg18NCBI36
Build 34632,817,140 - 32,823,199NCBI
Celera634,259,259 - 34,264,762 (+)NCBI
Cytogenetic Map6p21.32NCBI
HuRef632,452,649 - 32,458,152 (+)NCBIHuRef
CHM1_1632,711,607 - 32,717,109 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on HLA-DQA2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350485
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-05-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.