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Gene: RCAN1 (regulator of calcineurin 1) Homo sapiens
Symbol: RCAN1
Name: regulator of calcineurin 1
RGD ID: 735348
Description: Exhibits identical protein binding activity. Involved in negative regulation of calcineurin-NFAT signaling cascade. Predicted to localize to cytoplasm. Implicated in Alzheimer's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADAPT78; calcipressin-1; calcium and oxidant-inducible mRNA; CSP1; Down syndrome candidate region 1; Down syndrome critical region gene 1; down syndrome critical region homolog 1 (human); down syndrome critical region protein 1; DSC1; DSCR1; MCIP1; modulatory calcineurin-interacting protein 1; myocyte-enriched calcineurin-interacting protein 1; near DSCR proline-rich protein; RCN1
Mus musculus (house mouse) : Rcan1 (regulator of calcineurin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rcan1 (regulator of calcineurin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rcan1 (regulator of calcineurin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RCAN1 (regulator of calcineurin 1)
Canis lupus familiaris (dog) : RCAN1 (regulator of calcineurin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rcan1 (regulator of calcineurin 1)
Sus scrofa (pig) : RCAN1 (regulator of calcineurin 1)
Chlorocebus sabaeus (African green monkey) : RCAN1 (regulator of calcineurin 1)
Heterocephalus glaber (naked mole-rat) : Rcan1 (regulator of calcineurin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2134,513,142 - 34,615,113 (-)EnsemblGRCh38hg38GRCh38
GRCh382134,516,442 - 34,615,123 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372135,888,782 - 35,987,382 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362134,810,652 - 34,909,252 (-)NCBINCBI36hg18NCBI36
Build 342134,810,655 - 34,821,131NCBI
Celera2121,088,350 - 21,186,950 (-)NCBI
Cytogenetic Map21q22.12ENTREZGENE
HuRef2121,367,653 - 21,466,258 (-)NCBIHuRef
CHM1_12135,450,988 - 35,549,719 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on RCAN1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735348
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-09-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.