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Gene: CSF2 (colony stimulating factor 2) Homo sapiens
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Symbol: CSF2
Name: colony stimulating factor 2
Description: Exhibits cytokine activity. Involved in several processes, including cellular response to granulocyte macrophage colony-stimulating factor stimulus; myeloid leukocyte differentiation; and positive regulation of macromolecule metabolic process. Localizes to the extracellular space and intracellular membrane-bounded organelle. Implicated in acute myeloid leukemia; juvenile myelomonocytic leukemia; neutropenia; pulmonary alveolar proteinosis; and visceral leishmaniasis. Biomarker of asthma; chronic obstructive pulmonary disease; and temporal arteritis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; GMCSF; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; molgramostim; molgramostin; sargramostim
Orthologs:
Mus musculus (house mouse) : Csf2 (colony stimulating factor 2 (granulocyte-macrophage))  MGI  Alliance
Rattus norvegicus (Norway rat) : Csf2 (colony stimulating factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csf2 (colony stimulating factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CSF2 (colony stimulating factor 2)
Canis lupus familiaris (dog) : CSF2 (colony stimulating factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csf2 (colony stimulating factor 2)
Sus scrofa (pig) : CSF2 (colony stimulating factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385132,073,789 - 132,076,170 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375131,409,485 - 131,411,863 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365131,437,384 - 131,439,758 (+)NCBINCBI36hg18NCBI36
Build 345131,437,383 - 131,439,758NCBI
Celera5127,539,561 - 127,541,935 (+)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5126,601,846 - 126,604,224 (+)NCBIHuRef
CHM1_15130,842,312 - 130,844,690 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CSF2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1354508
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-22
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.