CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: ferric oxide
Accession: CHEBI:50819
browse the term
Definition: An iron oxide that has formula Fe2O3.
Synonyms: exact_synonym: diiron trioxide; iron(3+) oxide; iron(III) oxide
related_synonym: Eisen(III)-oxid; Eisentrioxid; Formula=Fe2O3; InChI=1S/2Fe.3O; InChIKey=JEIPFZHSYJVQDO-UHFFFAOYSA-N; SMILES=O=[Fe]O[Fe]=O; iron trioxide
xref: CAS:1309-37-1; Drug_Central:4443; Gmelin:11092; KEGG:C19424; KEGG:D04168
xref_mesh: MESH:C000499
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Aatk
apoptosis-associated tyrosine kinase
increases expression
ISO
ferric oxide analog results in increased expression of AATK mRNA
CTD
PMID:25086211
NCBI chr10:105,290,752...105,327,219
Ensembl chr10:105,291,585...105,327,112
G
Abcg1
ATP binding cassette subfamily G member 1
increases expression
EXP
ferric oxide analog results in increased expression of ABCG1 mRNA
CTD
PMID:38615722
NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,126,687...9,182,948
G
Acan
aggrecan
increases expression
EXP
ferric oxide analog results in increased expression of ACAN mRNA
CTD
PMID:38615722
NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:132,981,582...133,043,627
G
Ache
acetylcholinesterase
decreases activity
ISO
ferric oxide results in decreased activity of ACHE protein
CTD
PMID:28993115
NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651
G
Acss2
acyl-CoA synthetase short-chain family member 2
increases expression
ISO
ferric oxide analog results in increased expression of ACSS2 mRNA
CTD
PMID:25086211
NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:144,004,336...144,059,675
G
Adgre1
adhesion G protein-coupled receptor E1
increases expression
ISO
ferric oxide analog results in increased expression of ADGRE1 mRNA
CTD
PMID:24525745
NCBI chr 9:2,329,398...2,484,959
Ensembl chr 9:2,242,474...2,398,000
G
Adm
adrenomedullin
increases expression
ISO
ferric oxide analog results in increased expression of ADM mRNA
CTD
PMID:25086211
NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:164,745,466...164,747,654
G
Adora2b
adenosine A2B receptor
increases expression
ISO
ferric oxide analog results in increased expression of ADORA2B mRNA
CTD
PMID:25086211
NCBI chr10:47,439,712...47,456,092
Ensembl chr10:46,940,384...46,956,772
G
Agtr2
angiotensin II receptor, type 2
decreases expression
EXP
ferric oxide analog results in decreased expression of AGTR2 mRNA
CTD
PMID:38615722
NCBI chr X:116,914,320...116,918,504
Ensembl chr X:112,120,228...112,124,057
G
Ahnak2
AHNAK nucleoprotein 2
increases expression
ISO
ferric oxide analog results in increased expression of AHNAK2 mRNA
CTD
PMID:25086211
NCBI chr 6:137,648,867...137,697,580
Ensembl chr 6:131,831,454...131,854,463
G
Ahrr
aryl-hydrocarbon receptor repressor
increases expression
ISO EXP
ferric oxide analog results in increased expression of AHRR mRNA
CTD
PMID:24525745 PMID:38615722
NCBI chr 1:30,822,219...30,917,251
Ensembl chr 1:28,993,634...29,088,673
G
Aig1
androgen-induced 1
increases expression
ISO
ferric oxide analog results in increased expression of AIG1 mRNA
CTD
PMID:25086211
NCBI chr 1:9,866,546...10,089,454
Ensembl chr 1:8,046,430...8,269,084
G
Akt1
AKT serine/threonine kinase 1
multiple interactions
EXP
[ferric oxide analog co-treated with Acrolein] results in increased phosphorylation of AKT1 protein
CTD
PMID:24847785
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
G
Alas1
5'-aminolevulinate synthase 1
increases expression
EXP
ferric oxide analog results in increased expression of ALAS1 mRNA
CTD
PMID:38615722
NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:106,876,514...106,889,917
G
Aldh1a2
aldehyde dehydrogenase 1 family, member A2
decreases expression
EXP
ferric oxide analog results in decreased expression of ALDH1A2 mRNA
CTD
PMID:38615722
NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:71,877,850...71,957,107
G
Aldh1l2
aldehyde dehydrogenase 1 family, member L2
decreases expression
ISO
ferric oxide analog results in decreased expression of ALDH1L2 mRNA
CTD
PMID:25086211
NCBI chr 7:22,141,872...22,193,403
Ensembl chr 7:20,254,233...20,305,776
G
Angpt1
angiopoietin 1
increases expression
EXP
ferric oxide analog results in increased expression of ANGPT1 mRNA
CTD
PMID:38615722
NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:73,531,486...73,784,067
G
Angptl2
angiopoietin-like 2
decreases expression
EXP
ferric oxide analog results in decreased expression of ANGPTL2 mRNA
CTD
PMID:38615722
NCBI chr 3:36,914,876...36,944,715
Ensembl chr 3:16,517,420...16,548,178
G
Ankrd12
ankyrin repeat domain 12
decreases expression
ISO
ferric oxide analog results in decreased expression of ANKRD12 mRNA
CTD
PMID:24525745
NCBI chr 9:113,030,127...113,134,816
Ensembl chr 9:105,584,065...105,687,911
G
Anln
anillin, actin binding protein
decreases expression increases expression
ISO
ferric oxide analog results in decreased expression of ANLN mRNA ferric oxide analog results in increased expression of ANLN mRNA
CTD
PMID:24525745 PMID:25086211
NCBI chr 8:29,134,222...29,197,513
Ensembl chr 8:20,858,228...20,921,538
G
Anxa3
annexin A3
decreases expression
ISO
ferric oxide analog results in decreased expression of ANXA3 mRNA
CTD
PMID:25086211
NCBI chr14:13,031,675...13,085,678
Ensembl chr14:12,719,795...12,781,617
G
Aox1
aldehyde oxidase 1
increases expression
EXP
ferric oxide analog results in increased expression of AOX1 mRNA
CTD
PMID:38615722
NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:59,579,649...59,658,770
G
Ap5b1
adaptor related protein complex 5 subunit beta 1
decreases expression
ISO
ferric oxide analog results in decreased expression of AP5B1 mRNA
CTD
PMID:25086211
NCBI chr 1:212,305,612...212,309,643
Ensembl chr 1:202,876,272...202,880,289
G
Arhgap24
Rho GTPase activating protein 24
increases expression
ISO
ferric oxide analog results in increased expression of ARHGAP24 mRNA
CTD
PMID:25086211
NCBI chr14:7,105,200...7,488,437
Ensembl chr14:6,800,631...7,183,823
G
Atf3
activating transcription factor 3
increases expression
ISO
ferric oxide analog results in increased expression of ATF3 protein
CTD
PMID:24068039
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:102,751,321...102,764,631
G
Atg5
autophagy related 5
increases expression
ISO
ferric oxide analog results in increased expression of ATG5 protein
CTD
PMID:24068039
NCBI chr20:49,380,835...49,471,826
Ensembl chr20:47,798,290...47,889,209
G
Atosa
atos homolog A
increases expression
ISO
ferric oxide analog results in increased expression of ATOSA mRNA
CTD
PMID:25086211
NCBI chr 8:84,575,360...84,653,103
Ensembl chr 8:75,695,022...75,772,549
G
B3galnt1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
increases expression
ISO
ferric oxide analog results in increased expression of B3GALNT1 mRNA
CTD
PMID:24525745
NCBI chr 2:156,157,234...156,187,037
Ensembl chr 2:153,846,474...153,877,332
G
B3galt2
Beta-1,3-galactosyltransferase 2
decreases expression
EXP
ferric oxide analog results in decreased expression of B3GALT2 mRNA
CTD
PMID:38615722
NCBI chr13:57,939,724...57,948,735
Ensembl chr13:55,389,406...55,398,419
G
Bax
BCL2 associated X, apoptosis regulator
multiple interactions increases phosphorylation decreases expression increases expression
ISO EXP
bromotetrandrine promotes the reaction [[ferric oxide co-treated with ferrous oxide co-treated with Daunorubicin] results in increased expression of BAX protein] ferric oxide analog results in increased phosphorylation of BAX protein ferric oxide results in decreased expression of BAX protein ferric oxide results in increased expression of BAX protein
CTD
PMID:19421372 PMID:22995439 PMID:25086211 PMID:26991130
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
G
Bcl2
BCL2, apoptosis regulator
increases phosphorylation increases expression
EXP ISO
ferric oxide analog results in increased phosphorylation of BCL2 protein ferric oxide analog results in increased expression of BCL2 protein ferric oxide results in increased expression of BCL2 mRNA
CTD
PMID:22995439 PMID:25086211 PMID:33554279
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Bcl2l11
Bcl2-like 11
increases expression
ISO
ferric oxide analog results in increased expression of BCL2L11 mRNA; ferric oxide analog results in increased expression of BCL2L11 protein
CTD
PMID:24525745 PMID:25086211
NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:115,366,646...115,404,068
G
Bdh2
3-hydroxybutyrate dehydrogenase 2
increases expression
ISO
ferric oxide analog results in increased expression of BDH2 mRNA
CTD
PMID:25086211
NCBI chr 2:226,376,346...226,397,010
Ensembl chr 2:223,702,412...223,723,072
G
Becn1
beclin 1
decreases expression increases expression
ISO
ferric oxide results in decreased expression of BECN1 protein ferric oxide analog results in increased expression of BECN1 protein
CTD
PMID:24068039 PMID:25086211
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742
G
Bhlhe40
basic helix-loop-helix family, member e40
increases expression
ISO
ferric oxide analog results in increased expression of BHLHE40 mRNA
CTD
PMID:25086211
NCBI chr 4:143,174,450...143,180,150
Ensembl chr 4:141,618,476...141,624,774
G
Bmp2
bone morphogenetic protein 2
increases expression
EXP
ferric oxide analog results in increased expression of BMP2 mRNA
CTD
PMID:38615722
NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397
G
C1s
complement C1s
increases expression
EXP
ferric oxide analog results in increased expression of C1S mRNA
CTD
PMID:38615722
NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:157,430,117...157,442,303
G
Canx
calnexin
decreases expression
ISO
ferric oxide results in decreased expression of CANX protein
CTD
PMID:25086211
NCBI chr10:35,124,941...35,157,954
Ensembl chr10:34,625,191...34,656,821
G
Car5b
carbonic anhydrase 5B
increases expression
EXP
ferric oxide analog results in increased expression of CAR5B mRNA
CTD
PMID:38615722
NCBI chr X:34,106,553...34,166,651
Ensembl chr X:30,474,784...30,533,837
G
Casp3
caspase 3
multiple interactions increases cleavage increases expression affects activity
ISO
bromotetrandrine promotes the reaction [[ferric oxide co-treated with ferrous oxide co-treated with Daunorubicin] results in increased expression of CASP3 protein] ferric oxide results in increased cleavage of CASP3 protein ferric oxide results in increased expression of CASP3 protein modified form ferric oxide affects the activity of CASP3 protein
CTD
PMID:19421372 PMID:26991130 PMID:33554279
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
G
Casp9
caspase 9
increases activity
ISO
ferric oxide results in increased activity of CASP9 protein
CTD
PMID:33554279
Ensembl chr 5:154,109,046...154,126,626
G
Castor1
cytosolic arginine sensor for mTORC1 subunit 1
increases expression
ISO
ferric oxide analog results in increased expression of CASTOR1 mRNA
CTD
PMID:25086211
NCBI chr14:83,309,710...83,314,123
Ensembl chr14:79,086,136...79,090,548
G
Cat
catalase
decreases activity decreases expression
ISO
ferric oxide results in decreased activity of CAT protein ferric oxide results in decreased expression of CAT protein
CTD
PMID:19699289 PMID:26991130 PMID:28993115
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
G
Ccdc85b
coiled-coil domain containing 85B
increases expression
ISO
ferric oxide analog results in increased expression of CCDC85B mRNA
CTD
PMID:25086211
NCBI chr 1:212,192,979...212,193,994
Ensembl chr 1:202,763,631...202,764,703
G
Ccl11
C-C motif chemokine ligand 11
multiple interactions increases expression
ISO
ferric oxide results in increased expression of and results in increased secretion of CCL11 protein; RAG1 promotes the reaction [ferric oxide analog results in increased expression of CCL11 protein]
CTD
PMID:34982504 PMID:36935073
NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,028,328...67,032,926
G
Ccl2
C-C motif chemokine ligand 2
increases secretion increases expression
ISO EXP
ferric oxide results in increased secretion of CCL2 protein ferric oxide analog results in increased expression of CCL2 mRNA
CTD
PMID:24885771 PMID:38615722
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226
G
Ccl20
C-C motif chemokine ligand 20
increases expression
EXP
ferric oxide analog results in increased expression of CCL20 mRNA
CTD
PMID:38615722
NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:84,388,904...84,391,629
G
Ccl22
C-C motif chemokine ligand 22
increases secretion
ISO
ferric oxide results in increased secretion of CCL22 protein
CTD
PMID:24885771
NCBI chr19:10,263,589...10,270,359
Ensembl chr19:10,257,601...10,264,400
G
Ccl3
C-C motif chemokine ligand 3
increases secretion increases expression multiple interactions
ISO
ferric oxide results in increased secretion of CCL3 protein ferric oxide results in increased expression of CCL3 protein ferric oxide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein]
CTD
PMID:24885771 PMID:35872045 PMID:36416909
NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,451,388...68,452,938
G
Ccl4
C-C motif chemokine ligand 4
decreases expression increases secretion increases expression
ISO
ferric oxide analog results in decreased expression of CCL4 mRNA ferric oxide results in increased secretion of CCL4 protein ferric oxide results in increased expression of CCL4 protein
CTD
PMID:24525745 PMID:24885771 PMID:35872045
NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,452,052...68,468,231
G
Ccl5
C-C motif chemokine ligand 5
increases expression
EXP
ferric oxide analog results in increased expression of CCL5 mRNA
CTD
PMID:38615722
NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377
G
Ccl7
C-C motif chemokine ligand 7
increases secretion multiple interactions increases expression
ISO EXP
ferric oxide results in increased secretion of CCL7 protein ferric oxide results in increased expression of and results in increased secretion of CCL7 protein; RAG1 inhibits the reaction [ferric oxide analog results in increased expression of CCL7 protein] ferric oxide analog results in increased expression of CCL7 mRNA
CTD
PMID:24885771 PMID:34982504 PMID:36935073 PMID:38615722
NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,016,446...67,018,303
G
Cd14
CD14 molecule
decreases expression
ISO
ferric oxide analog results in decreased expression of CD14 mRNA
CTD
PMID:25086211
NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261
G
Cd274
CD274 molecule
increases expression
ISO
ferric oxide analog results in increased expression of CD274 mRNA
CTD
PMID:25086211
NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:227,116,649...227,134,450
G
Cd74
CD74 molecule
decreases expression
ISO
ferric oxide analog results in decreased expression of CD74 mRNA
CTD
PMID:25086211
NCBI chr18:56,527,071...56,536,406
Ensembl chr18:54,256,778...54,266,003
G
Cd83
CD83 molecule
increases expression
ISO
ferric oxide analog results in increased expression of CD83 mRNA
CTD
PMID:24525745 PMID:25086211
NCBI chr17:21,093,281...21,113,223
Ensembl chr17:20,887,309...20,907,083
G
Cdh1
cadherin 1
decreases expression
ISO EXP
ferric oxide results in decreased expression of CDH1 protein ferric oxide analog results in decreased expression of CDH1 mRNA
CTD
PMID:34982504 PMID:38615722
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775
G
Cdhr1
cadherin-related family member 1
increases expression
EXP
ferric oxide analog results in increased expression of CDHR1 mRNA
CTD
PMID:38615722
NCBI chr16:12,863,696...12,883,579
Ensembl chr16:12,843,437...12,863,396
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
EXP
ferric oxide analog results in increased expression of CDKN1A protein
CTD
PMID:22995439
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
multiple interactions
EXP
[ferric oxide analog co-treated with Acrolein] results in decreased expression of CDKN1B protein
CTD
PMID:24847785
NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
decreases expression
ISO
ferric oxide analog results in decreased expression of CDKN2A mRNA
CTD
PMID:24525745
NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149
G
Cep83
centrosomal protein 83
decreases expression
ISO
ferric oxide analog results in decreased expression of CEP83 mRNA
CTD
PMID:24525745
NCBI chr 7:31,167,198...31,276,513
Ensembl chr 7:29,280,419...29,389,574
G
Clec5a
C-type lectin domain containing 5A
decreases expression
ISO
ferric oxide analog results in decreased expression of CLEC5A mRNA
CTD
PMID:25086211
NCBI chr 4:70,373,855...70,383,560
Ensembl chr 4:69,407,835...69,416,859
G
Clk4
CDC-like kinase 4
increases expression
ISO
ferric oxide analog results in increased expression of CLK4 mRNA
CTD
PMID:25086211
NCBI chr10:36,024,364...36,042,366
Ensembl chr10:35,524,755...35,541,352
G
Cntn3
contactin 3
decreases expression
EXP
ferric oxide analog results in decreased expression of CNTN3 mRNA
CTD
PMID:38615722
NCBI chr 4:136,397,575...136,770,765
Ensembl chr 4:134,842,266...135,125,613
G
Col3a1
collagen type III alpha 1 chain
decreases expression
EXP
ferric oxide analog results in decreased expression of COL3A1 mRNA
CTD
PMID:38615722
NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:47,374,593...47,410,547
G
Col6a3
collagen type VI alpha 3 chain
increases expression
EXP
ferric oxide analog results in increased expression of COL6A3 mRNA
CTD
PMID:38615722
NCBI chr 9:98,809,171...98,887,060
Ensembl chr 9:91,361,583...91,439,471
G
Col8a1
collagen type VIII alpha 1 chain
decreases expression
EXP
ferric oxide analog results in decreased expression of COL8A1 mRNA
CTD
PMID:38615722
NCBI chr11:56,245,998...56,378,586
Ensembl chr11:42,777,628...42,906,424
G
Cox6a2
cytochrome c oxidase subunit 6A2
decreases expression
ISO
ferric oxide analog results in decreased expression of COX6A2 mRNA
CTD
PMID:25086211
NCBI chr 1:192,218,970...192,221,188
Ensembl chr 1:182,788,528...182,789,274
G
Crabp2
cellular retinoic acid binding protein 2
increases expression
EXP
ferric oxide analog results in increased expression of CRABP2 mRNA
CTD
PMID:38615722
NCBI chr 2:175,714,862...175,719,208
Ensembl chr 2:173,416,857...173,421,379
G
Csnk1e
casein kinase 1, epsilon
increases expression
ISO
ferric oxide analog results in increased expression of CSNK1E mRNA
CTD
PMID:25086211
NCBI chr 7:112,863,726...112,887,338
Ensembl chr 7:110,983,318...111,006,794
G
Cx3cr1
C-X3-C motif chemokine receptor 1
decreases expression
ISO
ferric oxide analog results in decreased expression of CX3CR1 mRNA
CTD
PMID:25086211
NCBI chr 8:128,661,294...128,679,048
Ensembl chr 8:119,782,595...119,800,014
G
Cxcl1
C-X-C motif chemokine ligand 1
increases expression
ISO EXP
ferric oxide results in increased expression of CXCL1 protein ferric oxide analog results in increased expression of CXCL1 mRNA
CTD
PMID:35872045 PMID:38615722
NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,193,365...17,195,215
G
Cxcl10
C-X-C motif chemokine ligand 10
increases expression
EXP
ferric oxide analog results in increased expression of CXCL10 mRNA
CTD
PMID:38615722
NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,704,758...15,706,975
G
Cxcl3
C-X-C motif chemokine ligand 3
multiple interactions increases expression
ISO
ferric oxide results in increased expression of and results in increased secretion of CXCL1 protein ferric oxide results in increased expression of CXCL1 protein
CTD
PMID:34982504 PMID:35872045
NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,270,146...17,289,511
G
Cxcr4
C-X-C motif chemokine receptor 4
increases expression
ISO
ferric oxide analog results in increased expression of CXCR4 mRNA
CTD
PMID:25086211
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:40,077,976...40,081,883
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions increases expression
EXP
ferric oxide promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A1 protein]; ferric oxide promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA] ferric oxide analog results in increased expression of CYP1A1 mRNA
CTD
PMID:15211619 PMID:38615722
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
increases expression
EXP
ferric oxide analog results in increased expression of CYP1B1 mRNA
CTD
PMID:38615722
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917
G
Ddit3
DNA-damage inducible transcript 3
increases expression decreases expression
ISO
ferric oxide analog results in increased expression of DDIT3 mRNA; ferric oxide analog results in increased expression of DDIT3 protein ferric oxide analog results in decreased expression of DDIT3 mRNA
CTD
PMID:24525745 PMID:25086211
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201
G
Ddit4
DNA-damage-inducible transcript 4
decreases expression
ISO
ferric oxide analog results in decreased expression of DDIT4 mRNA
CTD
PMID:24525745
NCBI chr20:28,434,938...28,437,037
Ensembl chr20:27,891,998...27,894,105
G
Dgkg
diacylglycerol kinase, gamma
decreases expression
ISO
ferric oxide analog results in decreased expression of DGKG mRNA
CTD
PMID:25086211
NCBI chr11:91,888,957...92,083,715
Ensembl chr11:78,384,458...78,577,212
G
Dock3
dedicator of cyto-kinesis 3
increases expression
EXP
ferric oxide analog results in increased expression of DOCK3 mRNA
CTD
PMID:38615722
NCBI chr 8:116,431,158...116,782,218
Ensembl chr 8:107,552,463...107,903,514
G
Dusp1
dual specificity phosphatase 1
decreases expression
ISO
ferric oxide analog results in decreased expression of DUSP1 mRNA
CTD
PMID:25086211
NCBI chr10:17,184,853...17,187,646
G
Dusp4
dual specificity phosphatase 4
increases expression
ISO
ferric oxide analog results in increased expression of DUSP4 mRNA
CTD
PMID:25086211
NCBI chr16:64,079,893...64,101,396
Ensembl chr16:57,377,229...57,398,138
G
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
decreases expression
ISO
ferric oxide analog results in decreased expression of EEF1A1 mRNA
CTD
PMID:25086211
NCBI chr 8:88,221,839...88,225,688
Ensembl chr 8:79,341,557...79,344,839
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Egfr
epidermal growth factor receptor
increases phosphorylation
ISO
ferric oxide analog results in increased phosphorylation of EGFR protein
CTD
PMID:24068039
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382
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Egr1
early growth response 1
decreases expression
ISO
ferric oxide analog results in decreased expression of EGR1 mRNA
CTD
PMID:25086211
NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766
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Egr2
early growth response 2
increases expression
ISO
ferric oxide analog results in increased expression of EGR2 mRNA
CTD
PMID:24525745 PMID:25086211
NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,051,277...21,055,562
G
Eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
decreases expression
ISO
ferric oxide analog results in decreased expression of EIF2AK2 mRNA
CTD
PMID:25086211
NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:16,188,979...16,224,971
G
Eno2
enolase 2
increases expression decreases expression
ISO
ferric oxide analog results in increased expression of ENO2 mRNA ferric oxide analog results in decreased expression of ENO2 mRNA
CTD
PMID:24525745 PMID:25086211
NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:157,572,088...157,580,980
G
Epn2
epsin 2
increases expression
ISO
ferric oxide analog results in increased expression of EPN2 mRNA
CTD
PMID:25086211
NCBI chr10:46,697,238...46,759,128
Ensembl chr10:46,197,785...46,259,642
G
Ern1
endoplasmic reticulum to nucleus signaling 1
multiple interactions
ISO
ferric oxide analog results in increased expression of and results in increased phosphorylation of ERN1 protein
CTD
PMID:25086211
NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029
G
Esm1
endothelial cell-specific molecule 1
increases expression
EXP
ferric oxide analog results in increased expression of ESM1 mRNA
CTD
PMID:38615722
NCBI chr 2:46,609,253...46,617,991
Ensembl chr 2:44,876,067...44,884,804
G
Fblim1
filamin binding LIM protein 1
increases expression
ISO
ferric oxide analog results in increased expression of FBLIM1 mRNA
CTD
PMID:25086211
NCBI chr 5:159,167,004...159,198,578
Ensembl chr 5:153,883,960...153,913,757
G
Filip1
filamin A interacting protein 1
increases expression
EXP
ferric oxide analog results in increased expression of FILIP1 mRNA
CTD
PMID:38615722
NCBI chr 8:89,641,509...89,836,772
Ensembl chr 8:80,764,604...80,922,549
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
decreases expression increases expression
ISO
ferric oxide analog results in decreased expression of FOS mRNA ferric oxide analog results in increased expression of FOS mRNA
CTD
PMID:24525745 PMID:25086211
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036
G
Fosb
FosB proto-oncogene, AP-1 transcription factor subunit
increases expression
EXP
ferric oxide analog results in increased expression of FOSB mRNA
CTD
PMID:38615722
NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465
G
Fosl1
FOS like 1, AP-1 transcription factor subunit
increases expression
EXP
ferric oxide analog results in increased expression of FOSL1 mRNA
CTD
PMID:38615722
NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:202,754,529...202,764,930
G
Fus
Fus RNA binding protein
decreases expression
ISO
ferric oxide analog results in decreased expression of FUS mRNA
CTD
PMID:25086211
NCBI chr 1:192,007,011...192,020,887
Ensembl chr 1:182,576,545...182,590,414
G
Fyb1
FYN binding protein 1
decreases expression
ISO
ferric oxide analog results in decreased expression of FYB1 mRNA
CTD
PMID:25086211
NCBI chr 2:57,360,084...57,508,609
Ensembl chr 2:55,632,698...55,779,629
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases phosphorylation
EXP
ferric oxide analog results in increased phosphorylation of GADD45A protein
CTD
PMID:22995439
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115
G
Gadd45b
growth arrest and DNA-damage-inducible, beta
increases expression
ISO
ferric oxide analog results in increased expression of GADD45B mRNA
CTD
PMID:25086211
NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:8,778,007...8,780,046
G
Gbp2
guanylate binding protein 2
increases expression
EXP
ferric oxide analog results in increased expression of GBP2 mRNA
CTD
PMID:38615722
NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:231,332,284...231,348,571
G
Gja1
gap junction protein, alpha 1
increases expression
ISO
ferric oxide analog results in increased expression of GJA1 mRNA
CTD
PMID:25086211
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582
G
Gpnmb
glycoprotein nmb
increases expression
EXP
ferric oxide analog results in increased expression of GPNMB mRNA
CTD
PMID:38615722
NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:78,010,197...78,049,367
G
Gpr183
G protein-coupled receptor 183
increases expression
ISO
ferric oxide analog results in increased expression of GPR183 mRNA
CTD
PMID:24525745
NCBI chr15:105,445,129...105,457,192
Ensembl chr15:99,036,367...99,050,559
G
Gpr84
G protein-coupled receptor 84
decreases expression increases expression
ISO
ferric oxide analog results in decreased expression of GPR84 mRNA ferric oxide analog results in increased expression of GPR84 mRNA
CTD
PMID:24525745 PMID:25086211
NCBI chr 7:134,443,904...134,446,173
Ensembl chr 7:134,443,936...134,446,178
G
Gsr
glutathione-disulfide reductase
multiple interactions
ISO
[Benzo(a)pyrene co-treated with ferric oxide] results in increased activity of GSR protein
CTD
PMID:11033230
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661
G
Gsta1
glutathione S-transferase alpha 1
increases expression
EXP
ferric oxide analog results in increased expression of GSTA1 mRNA
CTD
PMID:38615722
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:23,703,477...23,720,121
G
Gstp1
glutathione S-transferase pi 1
increases expression
EXP
ferric oxide analog results in increased expression of GSTP1 mRNA
CTD
PMID:38615722
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226
G
H2ax
H2A.X variant histone
multiple interactions increases expression
ISO
Oxygen deficiency inhibits the reaction [ferric oxide analog results in increased expression of H2AX protein]
CTD
PMID:27270449
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
G
H2bc8
H2B clustered histone 8
decreases expression
ISO
ferric oxide analog results in decreased expression of H2BC7 mRNA
CTD
PMID:24525745 PMID:25086211
NCBI chr17:47,404,405...47,405,155
G
H2bc9
H2B clustered histone 9
decreases expression
ISO
ferric oxide analog results in decreased expression of H2BC9 mRNA
CTD
PMID:24525745 PMID:25086211
NCBI chr17:47,166,372...47,174,369
G
H3c1
H3 clustered histone 1
decreases expression
ISO
ferric oxide analog results in decreased expression of H3C1 mRNA
CTD
PMID:25086211
NCBI chr17:41,796,236...41,796,759
Ensembl chr17:41,368,386...41,368,856 Ensembl chr17:41,368,386...41,368,856 Ensembl chr17:41,368,386...41,368,856 Ensembl chr17:41,368,386...41,368,856
G
Hbegf
heparin-binding EGF-like growth factor
increases expression
ISO
ferric oxide analog results in increased expression of HBEGF mRNA
CTD
PMID:25086211
NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,105,760...28,116,441
G
Heatr3
HEAT repeat containing 3
decreases expression
ISO
ferric oxide analog results in decreased expression of HEATR3 mRNA
CTD
PMID:25086211
NCBI chr19:35,065,915...35,103,779
Ensembl chr19:18,893,144...18,930,509
G
Hebp1
heme binding protein 1
increases expression
ISO
ferric oxide analog results in increased expression of HEBP1 mRNA
CTD
PMID:25086211
NCBI chr 4:169,705,665...169,735,199
Ensembl chr 4:167,974,319...168,003,854
G
Hilpda
hypoxia inducible lipid droplet-associated
increases expression
ISO
ferric oxide analog results in increased expression of HILPDA mRNA
CTD
PMID:25086211
NCBI chr 4:58,836,463...58,839,423
Ensembl chr 4:57,871,110...57,874,557
G
Hist1h2ail1
histone cluster 1 H2a family member I like 1
decreases expression
ISO
ferric oxide analog results in decreased expression of H3C6 mRNA
CTD
PMID:25086211
NCBI chr17:41,996,216...41,997,128
Ensembl chr17:41,568,471...41,569,109
G
Hist1h4b
histone cluster 1 H4 family member B
decreases expression
EXP
ferric oxide analog results in decreased expression of HIST1H4B mRNA
CTD
PMID:38615722
NCBI chr17:47,176,246...47,180,690
Ensembl chr17:42,480,313...42,485,370
G
Hist2h2be
histone cluster 2 H2B family member E
decreases expression increases expression
ISO
ferric oxide analog results in decreased expression of H2BC11 mRNA ferric oxide analog results in increased expression of H2BC21 mRNA
CTD
PMID:25086211
NCBI chr 2:186,469,452...186,471,899
G
Hmox1
heme oxygenase 1
increases expression
ISO EXP
ferric oxide analog results in increased expression of HMOX1 mRNA
CTD
PMID:24525745 PMID:25086211 PMID:38615722
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
G
Hsd11b1
hydroxysteroid 11-beta dehydrogenase 1
increases expression
EXP
ferric oxide analog results in increased expression of HSD11B1 mRNA
CTD
PMID:38615722
NCBI chr13:107,277,526...107,327,462
Ensembl chr13:104,728,539...104,788,687
G
Hsd3b7
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
increases expression
ISO
ferric oxide analog results in increased expression of HSD3B7 mRNA
CTD
PMID:25086211
NCBI chr 1:191,842,688...191,845,919
Ensembl chr 1:182,412,151...182,415,442
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
multiple interactions
ISO
[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of HSPA1A mRNA
CTD
PMID:20540983
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227
G
Hspa8
heat shock protein family A (Hsp70) member 8
multiple interactions
ISO
[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of HSPA8 mRNA
CTD
PMID:20540983
NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:41,183,264...41,187,259
G
Hspd1
heat shock protein family D (Hsp60) member 1
decreases expression
ISO
ferric oxide results in decreased expression of HSPD1 protein
CTD
PMID:28077287
NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:56,579,201...56,589,662
G
Hyal1
hyaluronidase 1
increases expression decreases expression
ISO
ferric oxide analog results in increased expression of HYAL1 mRNA ferric oxide analog results in decreased expression of HYAL1 mRNA
CTD
PMID:24525745 PMID:25086211
NCBI chr 8:117,129,311...117,133,162
Ensembl chr 8:108,250,667...108,260,210
G
Icam1
intercellular adhesion molecule 1
increases expression
ISO
ferric oxide results in increased expression of ICAM1 protein
CTD
PMID:21439359
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438
G
Icam2
intercellular adhesion molecule 2
decreases expression
ISO
ferric oxide analog results in decreased expression of ICAM2 mRNA
CTD
PMID:25086211
NCBI chr10:91,808,449...91,819,319
Ensembl chr10:91,308,538...91,315,293
G
Id1
inhibitor of DNA binding 1
increases expression
ISO
ferric oxide analog results in increased expression of ID1 mRNA
CTD
PMID:24525745
NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:141,211,267...141,212,419
G
Id3
inhibitor of DNA binding 3
increases expression
ISO
ferric oxide analog results in increased expression of ID3 mRNA
CTD
PMID:24525745
NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:148,372,762...148,374,349
G
Il10ra
interleukin 10 receptor subunit alpha
decreases expression
ISO
ferric oxide analog results in decreased expression of IL10RA mRNA
CTD
PMID:25086211
NCBI chr 8:54,459,754...54,474,786
Ensembl chr 8:45,563,137...45,578,061
G
Il12b
interleukin 12B
multiple interactions
ISO
ferric oxide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein]
CTD
PMID:36416909
NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903
G
Il13
interleukin 13
multiple interactions increases expression
ISO
RAG1 promotes the reaction [ferric oxide analog results in increased expression of IL13 protein]
CTD
PMID:36935073
NCBI chr10:38,290,926...38,293,483
Ensembl chr10:37,790,130...37,792,737
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Il17a
interleukin 17A
multiple interactions
ISO
ferric oxide results in increased expression of and results in increased secretion of IL17A protein
CTD
PMID:34982504
NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:23,144,402...23,147,889
G
Il1b
interleukin 1 beta
increases secretion
ISO
ferric oxide analog results in increased secretion of IL1B protein ferric oxide results in increased secretion of IL1B protein
CTD
PMID:24525745 PMID:24885771
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
G
Il1rl2
interleukin 1 receptor-like 2
increases expression
EXP
ferric oxide analog results in increased expression of IL1RL2 mRNA
CTD
PMID:38615722
NCBI chr 9:50,087,271...50,134,225
Ensembl chr 9:42,591,934...42,636,667
G
Il2
interleukin 2
multiple interactions
ISO
[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of IL2 protein
CTD
PMID:20540983
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566
G
Il33
interleukin 33
multiple interactions
ISO
ferric oxide results in increased expression of and results in increased secretion of IL33 protein
CTD
PMID:34982504
NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:227,721,435...227,736,373
G
Il4
interleukin 4
multiple interactions
ISO
[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of IL4 protein; ferric oxide inhibits the reaction [Ovalbumin results in increased expression of IL4 protein]
CTD
PMID:20540983 PMID:23147377
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
G
Il4i1
interleukin 4 induced 1
decreases expression
ISO
ferric oxide analog results in decreased expression of IL4I1 mRNA
CTD
PMID:25086211
NCBI chr 1:104,435,540...104,461,049
Ensembl chr 1:95,295,601...95,324,562
G
Il5
interleukin 5
multiple interactions
ISO
[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of IL5 protein; ferric oxide results in increased expression of and results in increased secretion of IL5 protein
CTD
PMID:20540983 PMID:34982504
NCBI chr10:38,375,132...38,378,003
Ensembl chr10:37,874,342...37,877,213
G
Il6
interleukin 6
multiple interactions increases secretion increases expression
ISO
[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of IL6 protein; RAG1 promotes the reaction [ferric oxide analog results in increased expression of IL6 protein] ferric oxide analog results in increased secretion of IL6 protein ferric oxide results in increased secretion of IL6 protein
CTD
PMID:20540983 PMID:24525745 PMID:24885771 PMID:36935073
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
G
Irf7
interferon regulatory factor 7
decreases expression
ISO
ferric oxide analog results in decreased expression of IRF7 mRNA
CTD
PMID:25086211
NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:196,367,361...196,370,832
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases phosphorylation
EXP
ferric oxide analog results in increased phosphorylation of JUN protein
CTD
PMID:22995439
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656
G
Klf2
KLF transcription factor 2
decreases expression
ISO
ferric oxide analog results in decreased expression of KLF2 mRNA
CTD
PMID:25086211
NCBI chr16:17,555,136...17,557,768
Ensembl chr16:17,514,552...17,523,944
G
Klf4
KLF transcription factor 4
decreases expression
ISO
ferric oxide analog results in decreased expression of KLF4 mRNA
CTD
PMID:25086211
NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:70,278,972...70,283,602
G
Klhl31
kelch-like family member 31
increases expression
EXP
ferric oxide analog results in increased expression of KLHL31 mRNA
CTD
PMID:38615722
NCBI chr 8:87,395,878...87,419,236
Ensembl chr 8:78,515,514...78,538,873
G
Lama3
laminin subunit alpha 3
increases expression
EXP
ferric oxide analog results in increased expression of LAMA3 mRNA
CTD
PMID:38615722
NCBI chr18:3,797,898...4,033,021
Ensembl chr18:3,523,133...3,751,353
G
Lamp1
lysosomal-associated membrane protein 1
multiple interactions
EXP
[ferric oxide analog co-treated with Acrolein] results in decreased expression of LAMP1 protein
CTD
PMID:24847785
NCBI chr16:83,058,131...83,082,843
Ensembl chr16:76,355,984...76,381,883
G
Lamp2
lysosomal-associated membrane protein 2
increases expression
ISO
ferric oxide analog results in increased expression of LAMP2 protein
CTD
PMID:25086211
NCBI chr X:122,038,734...122,087,745
Ensembl chr X:117,057,606...117,260,522
G
Lgals3
galectin 3
increases expression
EXP
ferric oxide analog results in increased expression of LGALS3 mRNA
CTD
PMID:38615722
NCBI chr15:23,099,795...23,111,731
Ensembl chr15:20,607,692...20,632,025
G
Lilrb4
leukocyte immunoglobulin like receptor B4
decreases expression
ISO
ferric oxide analog results in decreased expression of LILRB4B mRNA
CTD
PMID:24525745
NCBI chr 1:78,847,685...78,853,294
Ensembl chr 1:69,805,250...69,810,660
G
Lima1
LIM domain and actin binding 1
increases expression
ISO
ferric oxide analog results in increased expression of LIMA1 mRNA
CTD
PMID:25086211
NCBI chr 7:132,780,556...132,880,343
Ensembl chr 7:130,901,717...131,001,473
G
Lims2
LIM zinc finger domain containing 2
increases expression
ISO
ferric oxide analog results in increased expression of LIMS2 mRNA
CTD
PMID:25086211
NCBI chr18:23,828,164...23,866,363
Ensembl chr18:23,553,937...23,592,137
G
LOC120095805
U6 spliceosomal RNA
decreases expression
ISO
ferric oxide analog results in decreased expression of RNU6 mRNA
CTD
PMID:24525745
NCBI chr11:16,655,090...16,655,196
Ensembl chr11:16,655,090...16,655,196 Ensembl chr 1:16,655,090...16,655,196 Ensembl chr10:16,655,090...16,655,196 Ensembl chr13:16,655,090...16,655,196 Ensembl chr 3:16,655,090...16,655,196 Ensembl chr X:16,655,090...16,655,196 Ensembl chr 9:16,655,090...16,655,196 Ensembl chr 7:16,655,090...16,655,196 Ensembl chr 8:16,655,090...16,655,196 Ensembl chr18:16,655,090...16,655,196 Ensembl chr 7:16,655,090...16,655,196 Ensembl chr15:16,655,090...16,655,196 Ensembl chr17:16,655,090...16,655,196 Ensembl chr 9:16,655,090...16,655,196 Ensembl chr 8:16,655,090...16,655,196 Ensembl chr15:16,655,090...16,655,196 Ensembl chr 2:16,655,090...16,655,196 Ensembl chr16:16,655,090...16,655,196 Ensembl chr 6:16,655,090...16,655,196 Ensembl chr 2:16,655,090...16,655,196 Ensembl chr14:16,655,090...16,655,196 Ensembl chr18:16,655,090...16,655,196 Ensembl chr 6:16,655,090...16,655,196 Ensembl chr16:16,655,090...16,655,196 Ensembl chr 6:16,655,090...16,655,196 Ensembl chr 4:16,655,090...16,655,196 Ensembl chr 2:16,655,090...16,655,196 Ensembl chr17:16,655,090...16,655,196 Ensembl chr 6:16,655,090...16,655,196 Ensembl chr X:16,655,090...16,655,196 Ensembl chr 5:16,655,090...16,655,196 Ensembl chr 5:16,655,090...16,655,196 Ensembl chr10:16,655,090...16,655,196 Ensembl chr18:16,655,090...16,655,196 Ensembl chr 2:16,655,090...16,655,196 Ensembl chr 5:16,655,090...16,655,196 Ensembl chr 1:16,655,090...16,655,196 Ensembl chr 3:16,655,090...16,655,196 Ensembl chr X:16,655,090...16,655,196 Ensembl chr14:16,655,090...16,655,196 Ensembl chr14:16,655,090...16,655,196 Ensembl chr 2:16,655,090...16,655,196 Ensembl chr 2:16,655,090...16,655,196 Ensembl chr15:16,655,090...16,655,196 Ensembl chr 6:16,655,090...16,655,196 Ensembl chr14:16,655,090...16,655,196
G
Loxl4
lysyl oxidase-like 4
increases expression
EXP
ferric oxide analog results in increased expression of LOXL4 mRNA
CTD
PMID:38615722
NCBI chr 1:251,345,445...251,365,640
Ensembl chr 1:241,397,983...241,416,322
G
Lst1
leukocyte specific transcript 1
decreases expression
ISO
ferric oxide analog results in decreased expression of LST1 mRNA
CTD
PMID:24525745
NCBI chr20:3,639,353...3,644,399
Ensembl chr20:3,634,749...3,637,997
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Ly6a
lymphocyte antigen 6 family member A
decreases expression
ISO
ferric oxide analog results in decreased expression of LY6A mRNA
CTD
PMID:24525745
NCBI chr 7:109,064,222...109,067,757
Ensembl chr 7:107,183,469...107,189,981
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Lypd6
Ly6/Plaur domain containing 6
decreases expression
EXP
ferric oxide analog results in decreased expression of LYPD6 mRNA
CTD
PMID:38615722
NCBI chr 3:54,896,618...55,041,928
Ensembl chr 3:34,496,485...34,630,308
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Lyz2
lysozyme 2
decreases expression
ISO
ferric oxide analog results in decreased expression of LYZ2 mRNA
CTD
PMID:25086211
NCBI chr 7:54,792,715...54,798,060
Ensembl chr 7:52,906,811...52,912,106
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Mafb
MAF bZIP transcription factor B
increases expression
ISO
ferric oxide analog results in increased expression of MAFB mRNA
CTD
PMID:24525745
NCBI chr 3:169,417,890...169,419,810
Ensembl chr 3:148,998,122...149,000,031
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Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
increases expression
ISO
ferric oxide analog results in increased expression of MAP1LC3A protein
CTD
PMID:25086211
NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:143,783,024...143,784,670
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Map1lc3b
microtubule-associated protein 1 light chain 3 beta
increases expression
ISO
ferric oxide analog results in increased expression of MAP1LC3B protein
CTD
PMID:24068039
NCBI chr19:66,571,631...66,582,270
Ensembl chr19:49,665,791...49,677,690 Ensembl chr16:49,665,791...49,677,690
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Mapk1
mitogen activated protein kinase 1
increases phosphorylation multiple interactions
ISO EXP
ferric oxide analog results in increased phosphorylation of MAPK1 protein [ferric oxide analog co-treated with Acrolein] results in increased phosphorylation of MAPK1 protein
CTD
PMID:24068039 PMID:24847785
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
increases phosphorylation multiple interactions
ISO EXP
ferric oxide analog results in increased phosphorylation of MAPK3 protein [ferric oxide analog co-treated with Acrolein] results in increased phosphorylation of MAPK3 protein
CTD
PMID:24068039 PMID:24847785
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
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Mat2a
methionine adenosyltransferase 2A
decreases expression increases expression
ISO
ferric oxide analog results in decreased expression of MAT2A mRNA ferric oxide analog results in increased expression of MAT2A mRNA
CTD
PMID:24525745 PMID:25086211
NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:104,488,466...104,495,493
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Mef2c
myocyte enhancer factor 2C
decreases expression
ISO
ferric oxide analog results in decreased expression of MEF2C mRNA
CTD
PMID:25086211
NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:13,993,438...14,132,880
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Megf6
multiple EGF-like-domains 6
decreases expression
EXP
ferric oxide analog results in decreased expression of MEGF6 mRNA
CTD
PMID:38615722
NCBI chr 5:170,020,699...170,121,557
Ensembl chr 5:164,738,352...164,839,139
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Mgst1
microsomal glutathione S-transferase 1
increases expression
EXP
ferric oxide analog results in increased expression of MGST1 mRNA
CTD
PMID:38615722
NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:171,029,630...171,044,892
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Mmp12
matrix metallopeptidase 12
multiple interactions
ISO
[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of MMP12 mRNA
CTD
PMID:20540983
NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:4,581,785...4,599,611
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Mmp19
matrix metallopeptidase 19
multiple interactions
ISO
[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of MMP19 mRNA
CTD
PMID:20540983
NCBI chr 7:1,805,732...1,814,054
Ensembl chr 7:1,221,343...1,229,555
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Mmp2
matrix metallopeptidase 2
multiple interactions
ISO
[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of MMP2 mRNA
CTD
PMID:20540983
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870
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Mmp23
matrix metallopeptidase 23
multiple interactions
ISO
[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of MMP23 mRNA
CTD
PMID:20540983
NCBI chr 5:171,521,905...171,525,007
Ensembl chr 5:166,239,644...166,242,433
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Mmp7
matrix metallopeptidase 7
increases expression
ISO
ferric oxide results in increased expression of MMP7 protein
CTD
PMID:24885771
NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:4,848,186...4,855,902
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Mmp9
matrix metallopeptidase 9
increases expression
EXP
ferric oxide analog results in increased expression of MMP9 mRNA
CTD
PMID:38615722
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120
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Mnda
myeloid cell nuclear differentiation antigen
increases expression
EXP
ferric oxide analog results in increased expression of MNDA mRNA
CTD
PMID:38615722
NCBI chr13:88,550,224...88,567,892
Ensembl chr13:86,017,892...86,034,201
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Msmb
microseminoprotein, beta
affects expression
ISO
ferric oxide affects the expression of MSMB mRNA
CTD
PMID:28077287
NCBI chr16:7,366,536...7,387,124
Ensembl chr16:7,366,536...7,387,123
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Mt2
metallothionein 2
increases expression
EXP
ferric oxide analog results in increased expression of MT2A mRNA
CTD
PMID:38615722
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,832,002...10,832,784
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Myd88
MYD88, innate immune signal transduction adaptor
multiple interactions increases expression
ISO
oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine inhibits the reaction [ferric oxide results in increased expression of MYD88 protein] ferric oxide analog results in increased expression of MYD88 mRNA; ferric oxide analog results in increased expression of MYD88 protein; ferric oxide results in increased expression of MYD88 mRNA; ferric oxide results in increased expression of MYD88 protein
CTD
PMID:34982504 PMID:36935073
NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415
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N4bp3
Nedd4 binding protein 3
decreases expression
EXP
ferric oxide analog results in decreased expression of N4BP3 mRNA
CTD
PMID:38615722
NCBI chr10:36,400,053...36,407,609
Ensembl chr10:35,899,096...35,907,001
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Naa80
N(alpha)-acetyltransferase 80, NatH catalytic subunit
increases expression
ISO
ferric oxide analog results in increased expression of NAA80 mRNA
CTD
PMID:25086211
NCBI chr 8:117,132,957...117,136,207
Ensembl chr 8:108,253,302...108,257,563
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Nckap5l
NCK-associated protein 5-like
decreases expression
ISO
ferric oxide analog results in decreased expression of NCKAP5L mRNA
CTD
PMID:24525745
NCBI chr 7:130,553,683...130,591,886
Ensembl chr 7:130,555,368...130,591,857
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Ndrg1
N-myc downstream regulated 1
increases expression
ISO
ferric oxide analog results in increased expression of NDRG1 mRNA
CTD
PMID:25086211
NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:98,684,487...98,725,880
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Nedd9
neural precursor cell expressed, developmentally down-regulated 9
increases expression
ISO
ferric oxide analog results in increased expression of NEDD9 mRNA
CTD
PMID:24525745
NCBI chr17:23,495,531...23,673,780
Ensembl chr17:23,282,326...23,468,019
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Nfatc2
nuclear factor of activated T-cells 2
increases expression
EXP
ferric oxide analog results in increased expression of NFATC2 mRNA
CTD
PMID:38615722
NCBI chr 3:177,615,189...177,747,493
Ensembl chr 3:157,198,872...157,328,325
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Nfkb1
nuclear factor kappa B subunit 1
increases expression
ISO
ferric oxide results in increased expression of NFKB1 mRNA
CTD
PMID:34982504
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404
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Nox4
NADPH oxidase 4
increases expression
ISO
ferric oxide results in increased expression of NOX4 protein
CTD
PMID:28077287 PMID:28993115
NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:140,901,097...141,077,406
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Npm3
nucleophosmin/nucleoplasmin, 3
decreases expression
ISO
ferric oxide analog results in decreased expression of NPM3 mRNA
CTD
PMID:25086211
NCBI chr 1:244,595,638...244,597,623
Ensembl chr 1:244,595,644...244,597,591
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
EXP
ferric oxide analog results in increased expression of NQO1 mRNA
CTD
PMID:38615722
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557
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Nrp1
neuropilin 1
decreases expression
ISO
ferric oxide analog results in decreased expression of NRP1 mRNA
CTD
PMID:25086211
NCBI chr19:73,256,557...73,411,705
Ensembl chr19:56,359,455...56,513,633
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Nsg1
neuronal vesicle trafficking associated 1
increases expression
EXP
ferric oxide analog results in increased expression of NSG1 mRNA
CTD
PMID:38615722
NCBI chr14:76,861,079...76,882,822
Ensembl chr14:72,648,741...72,670,514
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Nt5c2
5'-nucleotidase, cytosolic II
increases expression
ISO
ferric oxide analog results in increased expression of NT5C2 mRNA
CTD
PMID:24525745
NCBI chr 1:255,712,797...255,838,285
Ensembl chr 1:245,772,277...245,897,913
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Nupr1
nuclear protein 1, transcriptional regulator
decreases expression
ISO
ferric oxide analog results in decreased expression of NUPR1 mRNA
CTD
PMID:24525745
NCBI chr 1:190,643,866...190,645,901
Ensembl chr 1:181,213,368...181,215,281
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Oas2
2'-5' oligoadenylate synthetase 2
decreases expression
ISO
ferric oxide analog results in decreased expression of OAS2 mRNA
CTD
PMID:25086211
NCBI chr12:41,464,568...41,492,036
Ensembl chr12:35,806,759...35,829,371
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Oasl
2'-5'-oligoadenylate synthetase-like
decreases expression
ISO
ferric oxide analog results in decreased expression of OASL1 mRNA
CTD
PMID:25086211
NCBI chr12:47,343,551...47,356,509
Ensembl chr12:41,682,900...41,695,641
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Osgin1
oxidative stress induced growth inhibitor 1
increases expression
EXP
ferric oxide analog results in increased expression of OSGIN1 mRNA
CTD
PMID:38615722
NCBI chr19:64,380,336...64,409,165
Ensembl chr19:47,492,171...47,500,516
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Pamr1
peptidase domain containing associated with muscle regeneration 1
increases expression
EXP
ferric oxide analog results in increased expression of PAMR1 mRNA
CTD
PMID:38615722
NCBI chr 3:88,889,061...88,988,615
Ensembl chr 3:88,889,046...88,988,606
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Pappa
pappalysin
increases expression
EXP
ferric oxide analog results in increased expression of PAPPA mRNA
CTD
PMID:38615722
NCBI chr 5:83,513,358...83,751,364
Ensembl chr 5:78,498,300...78,730,666
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Parp1
poly (ADP-ribose) polymerase 1
increases cleavage multiple interactions
ISO
ferric oxide analog results in increased cleavage of PARP1 protein ferric oxide results in increased cleavage of PARP1 protein ferric oxide results in decreased expression of and results in increased cleavage of PARP1 protein
CTD
PMID:26991130 PMID:27270449 PMID:28993115
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404
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Pate4
prostate and testis expressed 4
affects expression
ISO
ferric oxide affects the expression of PATE4 mRNA
CTD
PMID:28077287
NCBI chr 8:42,246,492...42,249,233
Ensembl chr 8:33,988,812...33,991,552 Ensembl chr 8:33,988,812...33,991,552
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Pcdh7
protocadherin 7
decreases expression
ISO
ferric oxide analog results in decreased expression of PCDH7 mRNA
CTD
PMID:25086211
NCBI chr14:56,684,817...57,114,976
Ensembl chr14:52,475,610...52,902,051 Ensembl chr14:52,475,610...52,902,051
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Pcsk5
proprotein convertase subtilisin/kexin type 5
decreases expression
EXP
ferric oxide analog results in decreased expression of PCSK5 mRNA
CTD
PMID:38615722
NCBI chr 1:224,263,823...224,694,350
Ensembl chr 1:214,837,927...215,267,600
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Pde2a
phosphodiesterase 2A
decreases expression
EXP
ferric oxide analog results in decreased expression of PDE2A mRNA
CTD
PMID:38615722
NCBI chr 1:165,235,623...165,327,466
Ensembl chr 1:155,813,180...155,915,434
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Per2
period circadian regulator 2
increases expression
ISO
ferric oxide analog results in increased expression of PER2 mRNA
CTD
PMID:25086211
NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:92,007,296...92,049,459
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Pes1
pescadillo ribosomal biogenesis factor 1
decreases expression
ISO
ferric oxide analog results in decreased expression of PES1 mRNA
CTD
PMID:25086211
NCBI chr14:78,850,754...78,867,134
Ensembl chr14:78,850,709...78,867,134
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Phlda1
pleckstrin homology-like domain, family A, member 1
increases expression
ISO
ferric oxide analog results in increased expression of PHLDA1 mRNA
CTD
PMID:25086211
NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:46,967,409...46,969,861
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Pla2g7
phospholipase A2 group VII
increases expression
EXP
ferric oxide analog results in increased expression of PLA2G7 mRNA
CTD
PMID:38615722
NCBI chr 9:24,859,491...24,901,747
Ensembl chr 9:17,362,225...17,404,476
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Plekhf1
pleckstrin homology and FYVE domain containing 1
increases expression
ISO
ferric oxide analog results in increased expression of PLEKHF1 mRNA
CTD
PMID:25086211
NCBI chr 1:100,045,340...100,046,817
Ensembl chr 1:90,904,742...90,915,820
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Plk2
polo-like kinase 2
increases expression
ISO
ferric oxide analog results in increased expression of PLK2 mRNA
CTD
PMID:25086211
NCBI chr 2:43,702,536...43,708,305
Ensembl chr 2:41,969,176...41,974,947
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Plk3
polo-like kinase 3
increases expression
ISO
ferric oxide analog results in increased expression of PLK3 mRNA
CTD
PMID:25086211
NCBI chr 5:135,843,725...135,848,900
Ensembl chr 5:130,607,142...130,612,317
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Plpbp
pyridoxal phosphate binding protein
increases expression
ISO
ferric oxide analog results in increased expression of PLPBP mRNA
CTD
PMID:25086211
NCBI chr16:65,003,292...65,014,886
Ensembl chr16:65,002,223...65,014,886
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Plppr4
phospholipid phosphatase related 4
decreases expression
EXP
ferric oxide analog results in decreased expression of PLPPR4 mRNA
CTD
PMID:38615722
NCBI chr 2:208,056,206...208,097,191
Ensembl chr 2:205,371,322...205,412,302
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Ppm1e
protein phosphatase, Mg2+/Mn2+ dependent, 1E
increases expression
EXP
ferric oxide analog results in increased expression of PPM1E mRNA
CTD
PMID:38615722
NCBI chr10:72,548,906...72,684,702
Ensembl chr10:72,055,208...72,187,282
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Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
decreases expression
ISO
ferric oxide analog results in decreased expression of PPP1R15A mRNA
CTD
PMID:24525745
NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:96,000,058...96,003,171
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Prf1
perforin 1
decreases expression
ISO
ferric oxide analog results in decreased expression of PRF1 mRNA
CTD
PMID:24525745
NCBI chr20:29,789,040...29,794,550
Ensembl chr20:29,246,202...29,251,701
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Prmt6
protein arginine methyltransferase 6
decreases expression
ISO
ferric oxide analog results in decreased expression of PRMT6 mRNA
CTD
PMID:25086211
NCBI chr 2:200,615,780...200,620,790
Ensembl chr 2:197,927,220...197,933,648
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Prr18
proline rich 18
increases expression
ISO
ferric oxide analog results in increased expression of PRR18 mRNA
CTD
PMID:25086211
NCBI chr 1:52,400,215...52,403,998
Ensembl chr 1:52,400,215...52,404,309
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Prr33
proline rich 33
decreases expression
ISO
ferric oxide analog results in decreased expression of PRR33 mRNA
CTD
PMID:25086211
NCBI chr 1:197,644,903...197,650,774
Ensembl chr 1:197,644,902...197,650,714
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Ptgr1
prostaglandin reductase 1
increases expression
EXP
ferric oxide analog results in increased expression of PTGR1 mRNA
CTD
PMID:38615722
NCBI chr 5:78,579,060...78,597,671
Ensembl chr 5:73,784,009...73,802,666
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Ptgs1
prostaglandin-endoperoxide synthase 1
increases expression
EXP
ferric oxide analog results in increased expression of PTGS1 mRNA
CTD
PMID:38615722
NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:19,584,015...19,605,586
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Rab15
RAB15, member RAS oncogene family
increases expression
ISO
ferric oxide analog results in increased expression of RAB15 mRNA
CTD
PMID:25086211
NCBI chr 6:101,232,740...101,257,388
Ensembl chr 6:95,499,587...95,523,942
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Rad50
RAD50 double strand break repair protein
decreases expression
ISO
ferric oxide analog results in decreased expression of RAD50 mRNA
CTD
PMID:24525745
NCBI chr10:38,310,147...38,362,100
Ensembl chr10:37,808,726...37,861,396
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Rag1
recombination activating 1
multiple interactions
ISO
RAG1 inhibits the reaction [ferric oxide analog results in increased expression of CCL7 protein]; RAG1 promotes the reaction [ferric oxide analog results in increased expression of CCL11 protein]; RAG1 promotes the reaction [ferric oxide analog results in increased expression of IL13 protein]; RAG1 promotes the reaction [ferric oxide analog results in increased expression of IL6 protein]; RAG1 promotes the reaction [ferric oxide analog results in increased expression of TNF protein]
CTD
PMID:36935073
NCBI chr 3:108,372,087...108,383,184
Ensembl chr 3:87,917,004...87,928,291
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Rbak
RB-associated KRAB zinc finger
increases expression
ISO
ferric oxide analog results in increased expression of RBAK mRNA
CTD
PMID:24525745
NCBI chr12:16,488,895...16,502,523
Ensembl chr12:11,375,318...11,388,934
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Rcan1
regulator of calcineurin 1
increases expression
ISO
ferric oxide analog results in increased expression of RCAN1 mRNA
CTD
PMID:25086211
NCBI chr11:45,108,123...45,188,065
Ensembl chr11:31,622,210...31,702,045
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Rcbtb2
RCC1 and BTB domain containing protein 2
increases expression
ISO
ferric oxide analog results in increased expression of RCBTB2 mRNA
CTD
PMID:24525745
NCBI chr15:54,729,367...54,774,004
Ensembl chr15:48,323,866...48,383,750
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Rgs16
regulator of G-protein signaling 16
increases expression
EXP
ferric oxide analog results in increased expression of RGS16 mRNA
CTD
PMID:38615722
NCBI chr13:68,421,480...68,443,312
Ensembl chr13:65,887,530...65,892,857
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Rilpl1
Rab interacting lysosomal protein-like 1
decreases expression
ISO
ferric oxide analog results in decreased expression of RILPL1 mRNA
CTD
PMID:24525745
NCBI chr12:37,732,847...37,770,659
Ensembl chr12:32,071,693...32,109,938
G
Ripk1
receptor interacting serine/threonine kinase 1
multiple interactions
EXP
[ferric oxide analog co-treated with Acrolein] results in increased expression of RIPK1 protein
CTD
PMID:24847785
NCBI chr17:31,044,983...31,077,167
Ensembl chr17:30,839,650...30,871,824
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Ripk3
receptor-interacting serine-threonine kinase 3
multiple interactions
EXP
[ferric oxide analog co-treated with Acrolein] results in increased expression of RIPK3 protein
CTD
PMID:24847785
NCBI chr15:33,253,071...33,262,025
Ensembl chr15:29,283,145...29,292,121
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RT1-A2
RT1 class Ia, locus A2
multiple interactions
ISO
[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of H2-T23 mRNA
CTD
PMID:20540983
NCBI chr20:4,872,720...4,876,425
G
RT1-Db1
RT1 class II, locus Db1
multiple interactions
ISO
[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of H2-EB1 mRNA
CTD
PMID:20540983
NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,548,666...4,558,258
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Rusc2
RUN and SH3 domain containing 2
increases expression
ISO
ferric oxide analog results in increased expression of RUSC2 mRNA
CTD
PMID:25086211
NCBI chr 5:62,424,185...62,471,317
Ensembl chr 5:57,629,904...57,675,524
G
Samd9l
sterile alpha motif domain containing 9 like
decreases expression
ISO
ferric oxide analog results in decreased expression of SAMD9L mRNA
CTD
PMID:25086211
NCBI chr 4:32,316,748...32,331,112
Ensembl chr 4:31,361,669...31,376,415
G
Scara5
scavenger receptor class A, member 5
increases expression
EXP
ferric oxide analog results in increased expression of SCARA5 mRNA
CTD
PMID:38615722
NCBI chr15:44,055,576...44,160,593
Ensembl chr15:39,880,035...39,983,373
G
Sema3a
semaphorin 3A
increases expression
EXP
ferric oxide analog results in increased expression of SEMA3A mRNA
CTD
PMID:38615722
NCBI chr 4:22,239,418...22,709,907
Ensembl chr 4:21,287,982...21,494,432
G
Sema3d
semaphorin 3D
decreases expression
EXP
ferric oxide analog results in decreased expression of SEMA3D mRNA
CTD
PMID:38615722
NCBI chr 4:23,271,815...23,460,971
Ensembl chr 4:22,316,779...22,505,930
G
Serpinb1a
serpin family B member 1A
decreases expression
ISO
ferric oxide analog results in decreased expression of SERPINB1A mRNA
CTD
PMID:24525745
NCBI chr17:31,799,446...31,807,853
Ensembl chr17:31,590,677...31,599,102
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Skil
SKI-like proto-oncogene
increases expression
ISO
ferric oxide analog results in increased expression of SKIL mRNA
CTD
PMID:24525745
NCBI chr 2:114,175,534...114,203,663
Ensembl chr 2:112,247,051...112,275,080
G
Slamf8
SLAM family member 8
increases expression
ISO
ferric oxide analog results in increased expression of SLAMF8 mRNA
CTD
PMID:24525745
NCBI chr13:87,580,081...87,589,941
Ensembl chr13:85,047,727...85,057,211
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Slc11a1
solute carrier family 11 member 1
increases expression
ISO
ferric oxide analog results in increased expression of SLC11A1 mRNA
CTD
PMID:25086211
NCBI chr 9:83,406,327...83,417,252
Ensembl chr 9:75,957,316...75,968,101
G
Slc30a3
solute carrier family 30 member 3
increases expression
EXP
ferric oxide analog results in increased expression of SLC30A3 mRNA
CTD
PMID:38615722
NCBI chr 6:30,984,241...31,004,689
Ensembl chr 6:25,275,528...25,284,720
G
Slc46a3
solute carrier family 46, member 3
decreases expression
ISO
ferric oxide analog results in decreased expression of SLC46A3 mRNA
CTD
PMID:25086211
NCBI chr12:12,176,776...12,193,256
Ensembl chr12:7,140,668...7,157,092
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Slc7a5
solute carrier family 7 member 5
decreases expression
EXP
ferric oxide analog results in decreased expression of SLC7A5 mRNA
CTD
PMID:38615722
NCBI chr19:66,843,808...66,872,412
Ensembl chr19:49,935,220...49,963,823
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Slco2a1
solute carrier organic anion transporter family, member 2a1
increases expression
EXP
ferric oxide analog results in increased expression of SLCO2A1 mRNA
CTD
PMID:38615722
NCBI chr 8:112,467,739...112,551,923
Ensembl chr 8:103,588,916...103,672,546
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Slpi
secretory leukocyte peptidase inhibitor
multiple interactions
ISO
[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of SLPI mRNA
CTD
PMID:20540983
NCBI chr 3:173,501,573...173,503,822
Ensembl chr 3:153,082,369...153,084,453
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Sod1
superoxide dismutase 1
increases expression
ISO
ferric oxide analog results in increased expression of SOD1 protein
CTD
PMID:24068039
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249
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Sod2
superoxide dismutase 2
increases expression
ISO
ferric oxide analog results in increased expression of SOD2 protein; ferric oxide results in increased expression of SOD2 protein
CTD
PMID:24068039 PMID:25086211 PMID:26991130
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
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Spata24
spermatogenesis associated 24
decreases expression
ISO
ferric oxide analog results in decreased expression of SPATA24 mRNA
CTD
PMID:24525745
NCBI chr18:27,523,133...27,531,375
Ensembl chr18:27,248,609...27,257,124
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Spock2
SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2
increases expression
EXP
ferric oxide analog results in increased expression of SPOCK2 mRNA
CTD
PMID:38615722
NCBI chr20:28,580,262...28,607,198
Ensembl chr20:28,033,475...28,064,272
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Spta1
spectrin, alpha, erythrocytic 1
increases expression
EXP
ferric oxide analog results in increased expression of SPTA1 mRNA
CTD
PMID:38615722
NCBI chr13:88,735,833...88,811,697
Ensembl chr13:86,203,504...86,279,371
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Srxn1
sulfiredoxin 1
increases expression
EXP
ferric oxide analog results in increased expression of SRXN1 mRNA
CTD
PMID:38615722
NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:140,599,608...140,628,448
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Stmn2
stathmin 2
increases expression
EXP
ferric oxide analog results in increased expression of STMN2 mRNA
CTD
PMID:38615722
NCBI chr 2:95,112,017...95,159,642
Ensembl chr 2:93,204,692...93,252,011
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Synpo2
synaptopodin 2
increases expression
EXP
ferric oxide analog results in increased expression of SYNPO2 mRNA
CTD
PMID:38615722
NCBI chr 2:213,901,685...214,055,844
Ensembl chr 2:211,216,783...211,371,267
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Tatdn2
TatD DNase domain containing 2
decreases expression
ISO
ferric oxide analog results in decreased expression of TATDN2 mRNA
CTD
PMID:24525745
NCBI chr 4:148,400,454...148,416,501
Ensembl chr 4:146,845,156...146,860,897
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Tbc1d2
TBC1 domain family, member 2
increases expression decreases expression
ISO
ferric oxide analog results in increased expression of TBC1D2 mRNA ferric oxide analog results in decreased expression of TBC1D2 mRNA
CTD
PMID:24525745 PMID:25086211
NCBI chr 5:65,679,670...65,727,978
Ensembl chr 5:60,884,124...60,931,352
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Tbxas1
thromboxane A synthase 1
increases expression
ISO
ferric oxide analog results in increased expression of TBXAS1 mRNA
CTD
PMID:24525745
NCBI chr 4:68,631,841...68,803,959
Ensembl chr 4:67,665,007...67,837,096
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Tf
transferrin
increases expression
EXP
ferric oxide results in increased expression of TF mRNA
CTD
PMID:16428268
NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:103,767,995...103,816,511
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Tfrc
transferrin receptor
decreases expression
ISO EXP
ferric oxide analog results in decreased expression of TFRC mRNA
CTD
PMID:25086211 PMID:38615722
NCBI chr11:81,668,478...81,690,318
Ensembl chr11:68,163,413...68,185,257
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Tgfa
transforming growth factor alpha
increases expression
EXP
ferric oxide analog results in increased expression of TGFA mRNA
CTD
PMID:38615722
NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:118,618,269...118,700,894
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Tgfbi
transforming growth factor, beta induced
increases expression
ISO
ferric oxide analog results in increased expression of TGFBI mRNA
CTD
PMID:24525745
NCBI chr17:7,960,885...7,990,234
Ensembl chr17:7,955,603...7,985,240
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Tgm2
transglutaminase 2
increases expression
ISO
ferric oxide analog results in increased expression of TGM2 mRNA
CTD
PMID:25086211
NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:146,772,687...146,801,981
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Thbs2
thrombospondin 2
decreases expression
EXP
ferric oxide analog results in decreased expression of THBS2 mRNA
CTD
PMID:38615722
NCBI chr 1:64,343,523...64,372,918
Ensembl chr 1:55,670,394...55,699,789
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Timp1
TIMP metallopeptidase inhibitor 1
multiple interactions
ISO
[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of TIMP1 mRNA
CTD
PMID:20540983
NCBI chr X:3,766,509...3,772,578
Ensembl chr X:1,212,972...1,217,664
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Timp2
TIMP metallopeptidase inhibitor 2
increases expression
ISO
ferric oxide results in increased expression of TIMP2 protein
CTD
PMID:24885771
NCBI chr10:104,041,604...104,089,214
Ensembl chr10:103,531,505...103,590,611
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Tlr2
toll-like receptor 2
increases expression multiple interactions
ISO
ferric oxide analog results in increased expression of TLR2 mRNA; ferric oxide analog results in increased expression of TLR2 protein; ferric oxide results in increased expression of TLR2 mRNA; ferric oxide results in increased expression of TLR2 protein oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine inhibits the reaction [ferric oxide results in increased expression of TLR2 protein]
CTD
PMID:24525745 PMID:34982504 PMID:36935073
NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630
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Tlr4
toll-like receptor 4
multiple interactions increases expression
ISO
oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine inhibits the reaction [ferric oxide results in increased expression of TLR4 protein] ferric oxide analog results in increased expression of TLR4 mRNA; ferric oxide analog results in increased expression of TLR4 protein; ferric oxide results in increased expression of TLR4 mRNA; ferric oxide results in increased expression of TLR4 protein
CTD
PMID:34982504 PMID:36935073
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628
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Tlr5
toll-like receptor 5
increases expression
EXP
ferric oxide analog results in increased expression of TLR5 mRNA
CTD
PMID:38615722
NCBI chr13:97,166,430...97,190,642
Ensembl chr13:94,634,801...94,657,738
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Tmem176a
transmembrane protein 176A
decreases expression
ISO
ferric oxide analog results in decreased expression of TMEM176A mRNA
CTD
PMID:25086211
NCBI chr 4:79,101,946...79,109,499
Ensembl chr 4:77,774,843...77,778,620
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Tnf
tumor necrosis factor
multiple interactions increases secretion increases expression
ISO
[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of TNF protein; ferric oxide results in increased expression of and results in increased secretion of TNF protein; oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine inhibits the reaction [ferric oxide results in increased expression of TNF protein]; RAG1 promotes the reaction [ferric oxide analog results in increased expression of TNF protein] ferric oxide analog results in increased secretion of TNF protein ferric oxide results in increased secretion of TNF protein ferric oxide analog results in increased expression of TNF mRNA; ferric oxide analog results in increased expression of TNF protein; ferric oxide results in increased expression of TNF mRNA
CTD
PMID:20540983 PMID:24068039 PMID:24525745 PMID:24885771 PMID:34982504 PMID:36935073 More...
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
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Tnni3
troponin I3, cardiac type
increases expression
ISO
ferric oxide results in increased expression of TNNI3 protein
CTD
PMID:28993115
NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:69,299,900...69,303,580
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Tox3
TOX high mobility group box family member 3
decreases expression
EXP
ferric oxide analog results in decreased expression of TOX3 mRNA
CTD
PMID:38615722
NCBI chr19:32,820,957...32,929,776
Ensembl chr19:16,648,342...16,757,148
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Tp53
tumor protein p53
increases phosphorylation multiple interactions
EXP
ferric oxide analog results in increased phosphorylation of TP53 protein [ferric oxide analog co-treated with Acrolein] results in increased expression of TP53 protein
CTD
PMID:22995439 PMID:24847785
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
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Tp53inp1
tumor protein p53 inducible nuclear protein 1
increases expression
ISO
ferric oxide analog results in increased expression of TRP53INP1 mRNA
CTD
PMID:25086211
NCBI chr 5:29,051,267...29,069,486
Ensembl chr 5:24,260,568...24,267,968
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Tpr
translocated promoter region, nuclear basket protein
decreases expression
ISO
ferric oxide analog results in decreased expression of TPR mRNA
CTD
PMID:24525745
NCBI chr13:64,974,419...65,037,604
Ensembl chr13:62,424,312...62,487,496
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Traf6
TNF receptor associated factor 6
increases expression
ISO
ferric oxide analog results in increased expression of TRAF6 mRNA; ferric oxide analog results in increased expression of TRAF6 protein; ferric oxide results in increased expression of TRAF6 mRNA; ferric oxide results in increased expression of TRAF6 protein
CTD
PMID:34982504 PMID:36935073
NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507
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Trib3
tribbles pseudokinase 3
decreases expression
ISO
ferric oxide analog results in decreased expression of TRIB3 mRNA
CTD
PMID:24525745
NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:140,809,043...140,814,497
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Tslp
thymic stromal lymphopoietin
multiple interactions
ISO
ferric oxide results in increased expression of and results in increased secretion of TSLP protein
CTD
PMID:34982504
NCBI chr18:24,723,990...24,728,419
Ensembl chr18:24,449,844...24,453,548
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Ttpal
alpha tocopherol transfer protein like
decreases expression
ISO
ferric oxide analog results in decreased expression of TTPAL mRNA
CTD
PMID:25086211
NCBI chr 3:172,697,683...172,715,973
Ensembl chr 3:152,278,303...152,296,513
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Tubb2b
tubulin, beta 2B class IIb
increases expression
ISO
ferric oxide analog results in increased expression of TUBB2B mRNA
CTD
PMID:24525745
NCBI chr17:30,953,086...30,956,133
Ensembl chr17:30,747,734...30,750,638
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Uchl1
ubiquitin C-terminal hydrolase L1
increases expression
EXP
ferric oxide analog results in increased expression of UCHL1 mRNA
CTD
PMID:38615722
NCBI chr14:41,838,859...41,849,743
Ensembl chr14:41,485,031...41,495,590
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Wdfy3
WD repeat and FYVE domain containing 3
increases expression
ISO
ferric oxide analog results in increased expression of WDFY3 mRNA
CTD
PMID:24525745
NCBI chr14:7,873,946...8,115,002
Ensembl chr14:7,606,628...7,810,482
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Yipf7
Yip1 domain family, member 7
increases expression
ISO
ferric oxide analog results in increased expression of YIPF7 mRNA
CTD
PMID:25086211
NCBI chr14:38,924,994...38,953,021
Ensembl chr14:38,571,066...38,599,055
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Zbtb2
zinc finger and BTB domain containing 2
decreases expression
ISO
ferric oxide analog results in decreased expression of ZBTB2 mRNA
CTD
PMID:24525745
NCBI chr 1:43,232,839...43,252,115
Ensembl chr 1:40,827,457...40,846,594
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Zc3h13
zinc finger CCCH type containing 13
increases expression
ISO
ferric oxide analog results in increased expression of ZC3H13 mRNA
CTD
PMID:24525745
NCBI chr15:57,016,686...57,081,201
Ensembl chr15:50,607,380...50,671,802
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Zfp36
zinc finger protein 36
increases expression
ISO
ferric oxide analog results in increased expression of ZFP36 mRNA
CTD
PMID:24525745
NCBI chr 1:92,796,628...92,799,108
Ensembl chr 1:83,669,084...83,671,564
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