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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:iron oxide
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Accession:CHEBI:50816 term browser browse the term

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ferric oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatk apoptosis-associated tyrosine kinase increases expression ISO ferric oxide analog results in increased expression of AATK mRNA CTD PMID:25086211 NCBI chr10:109,184,338...109,224,455
Ensembl chr10:109,188,112...109,224,370 		JBrowse link
G Ache acetylcholinesterase decreases activity ISO ferric oxide results in decreased activity of ACHE protein CTD PMID:28993115 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression ISO ferric oxide analog results in increased expression of ACSS2 mRNA CTD PMID:25086211 NCBI chr 3:151,032,925...151,075,856
Ensembl chr 3:151,032,952...151,075,856 		JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 increases expression ISO ferric oxide analog results in increased expression of ADGRE1 mRNA CTD PMID:24525745 NCBI chr 9:9,431,888...9,585,883
Ensembl chr 9:9,431,860...9,585,865 		JBrowse link
G Adm adrenomedullin increases expression ISO ferric oxide analog results in increased expression of ADM mRNA CTD PMID:25086211 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259 		JBrowse link
G Adora2b adenosine A2B receptor increases expression ISO ferric oxide analog results in increased expression of ADORA2B mRNA CTD PMID:25086211 NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365 		JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 increases expression ISO ferric oxide analog results in increased expression of AHNAK2 mRNA CTD PMID:25086211 NCBI chr 6:137,335,273...137,380,219 JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor increases expression ISO ferric oxide analog results in increased expression of AHRR mRNA CTD PMID:24525745 NCBI chr 1:31,603,297...31,698,329
Ensembl chr 1:31,603,297...31,698,329 		JBrowse link
G Aig1 androgen-induced 1 increases expression ISO ferric oxide analog results in increased expression of AIG1 mRNA CTD PMID:25086211 NCBI chr 1:7,816,841...8,038,805
Ensembl chr 1:7,816,838...8,038,665 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP [ferric oxide analog co-treated with Acrolein] results in increased phosphorylation of AKT1 protein CTD PMID:24847785 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 decreases expression ISO ferric oxide analog results in decreased expression of ALDH1L2 mRNA CTD PMID:25086211 NCBI chr 7:26,375,866...26,425,838
Ensembl chr 7:26,375,866...26,425,108 		JBrowse link
G Ankrd12 ankyrin repeat domain 12 decreases expression ISO ferric oxide analog results in decreased expression of ANKRD12 mRNA CTD PMID:24525745 NCBI chr 9:113,605,683...113,682,482
Ensembl chr 9:113,605,657...113,682,482 		JBrowse link
G Anln anillin, actin binding protein decreases expression
increases expression		 ISO ferric oxide analog results in decreased expression of ANLN mRNA
ferric oxide analog results in increased expression of ANLN mRNA		 CTD PMID:24525745 PMID:25086211 NCBI chr 8:23,336,455...23,397,122
Ensembl chr 8:23,337,621...23,390,773 		JBrowse link
G Anxa3 annexin A3 decreases expression ISO ferric oxide analog results in decreased expression of ANXA3 mRNA CTD PMID:25086211 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437 		JBrowse link
G Ap5b1 adaptor related protein complex 5 subunit beta 1 decreases expression ISO ferric oxide analog results in decreased expression of AP5B1 mRNA CTD PMID:25086211 NCBI chr 1:220,948,318...220,952,349
Ensembl chr 1:220,948,331...220,952,391 		JBrowse link
G Arhgap24 Rho GTPase activating protein 24 increases expression ISO ferric oxide analog results in increased expression of ARHGAP24 mRNA CTD PMID:25086211 NCBI chr14:8,383,211...8,600,526
Ensembl chr14:8,383,214...8,600,512 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO ferric oxide analog results in increased expression of ATF3 protein CTD PMID:24068039 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632 		JBrowse link
G Atg5 autophagy related 5 increases expression ISO ferric oxide analog results in increased expression of ATG5 protein CTD PMID:24068039 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140 		JBrowse link
G B3galnt1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) increases expression ISO ferric oxide analog results in increased expression of B3GALNT1 mRNA CTD PMID:24525745 NCBI chr 2:166,226,736...166,255,978
Ensembl chr 2:166,226,754...166,255,302 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
decreases expression
increases phosphorylation		 ISO
EXP		 bromotetrandrine promotes the reaction [[ferric oxide co-treated with ferrous oxide co-treated with Daunorubicin] results in increased expression of BAX protein]
ferric oxide results in increased expression of BAX protein
ferric oxide results in decreased expression of BAX protein
ferric oxide analog results in increased phosphorylation of BAX protein		 CTD PMID:19421372 PMID:22995439 PMID:25086211 PMID:26991130 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases phosphorylation
increases expression		 EXP
ISO		 ferric oxide analog results in increased phosphorylation of BCL2 protein
ferric oxide analog results in increased expression of BCL2 protein		 CTD PMID:22995439 PMID:25086211 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO ferric oxide analog results in increased expression of BCL2L11 mRNA; ferric oxide analog results in increased expression of BCL2L11 protein CTD PMID:24525745 PMID:25086211 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192 		JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 increases expression ISO ferric oxide analog results in increased expression of BDH2 mRNA CTD PMID:25086211 NCBI chr 2:240,461,505...240,482,149
Ensembl chr 2:240,461,505...240,482,145 		JBrowse link
G Becn1 beclin 1 decreases expression
increases expression		 ISO ferric oxide results in decreased expression of BECN1 protein
ferric oxide analog results in increased expression of BECN1 protein		 CTD PMID:24068039 PMID:25086211 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO ferric oxide analog results in increased expression of BHLHE40 mRNA CTD PMID:25086211 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319 		JBrowse link
G Canx calnexin decreases expression ISO ferric oxide results in decreased expression of CANX protein CTD PMID:25086211 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage		 ISO bromotetrandrine promotes the reaction [[ferric oxide co-treated with ferrous oxide co-treated with Daunorubicin] results in increased expression of CASP3 protein]
ferric oxide results in increased cleavage of CASP3 protein		 CTD PMID:19421372 PMID:26991130 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 increases expression ISO ferric oxide analog results in increased expression of CASTOR1 mRNA CTD PMID:25086211 NCBI chr14:84,447,552...84,457,396
Ensembl chr14:84,447,885...84,452,367 		JBrowse link
G Cat catalase decreases activity
decreases expression		 ISO ferric oxide results in decreased activity of CAT protein
ferric oxide results in decreased expression of CAT protein		 CTD PMID:19699289 PMID:26991130 PMID:28993115 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Ccdc85b coiled-coil domain containing 85B increases expression ISO ferric oxide analog results in increased expression of CCDC85B mRNA CTD PMID:25086211 NCBI chr 1:220,835,647...220,837,220 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion ISO ferric oxide results in increased secretion of CCL2 protein CTD PMID:24885771 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 increases secretion ISO ferric oxide results in increased secretion of CCL22 protein CTD PMID:24885771 NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases secretion ISO ferric oxide results in increased secretion of CCL3 protein CTD PMID:24885771 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression
increases secretion		 ISO ferric oxide analog results in decreased expression of CCL4 mRNA
ferric oxide results in increased secretion of CCL4 protein		 CTD PMID:24525745 PMID:24885771 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases secretion ISO ferric oxide results in increased secretion of CCL7 protein CTD PMID:24885771 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979 		JBrowse link
G Cd14 CD14 molecule decreases expression ISO ferric oxide analog results in decreased expression of CD14 mRNA CTD PMID:25086211 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153 		JBrowse link
G Cd274 CD274 molecule increases expression ISO ferric oxide analog results in increased expression of CD274 mRNA CTD PMID:25086211 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943 		JBrowse link
G Cd74 CD74 molecule decreases expression ISO ferric oxide analog results in decreased expression of CD74 mRNA CTD PMID:25086211 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849 		JBrowse link
G Cd83 CD83 molecule increases expression ISO ferric oxide analog results in increased expression of CD83 mRNA CTD PMID:24525745 PMID:25086211 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP ferric oxide analog results in increased expression of CDKN1A protein CTD PMID:22995439 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP [ferric oxide analog co-treated with Acrolein] results in decreased expression of CDKN1B protein CTD PMID:24847785 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression ISO ferric oxide analog results in decreased expression of CDKN2A mRNA CTD PMID:24525745 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175 		JBrowse link
G Cep83 centrosomal protein 83 decreases expression ISO ferric oxide analog results in decreased expression of CEP83 mRNA CTD PMID:24525745 NCBI chr 7:35,739,553...35,847,618
Ensembl chr 7:35,773,928...35,847,617 		JBrowse link
G Clec5a C-type lectin domain containing 5A decreases expression ISO ferric oxide analog results in decreased expression of CLEC5A mRNA CTD PMID:25086211 NCBI chr 4:68,810,330...68,819,921
Ensembl chr 4:68,808,359...68,819,928 		JBrowse link
G Clk4 CDC-like kinase 4 increases expression ISO ferric oxide analog results in increased expression of CLK4 mRNA CTD PMID:25086211 NCBI chr10:36,715,565...36,733,473
Ensembl chr10:36,715,565...36,733,133 		JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 decreases expression ISO ferric oxide analog results in decreased expression of COX6A2 mRNA CTD PMID:25086211 NCBI chr 1:199,624,037...199,626,255
Ensembl chr 1:199,624,037...199,624,783 		JBrowse link
G Csnk1e casein kinase 1, epsilon increases expression ISO ferric oxide analog results in increased expression of CSNK1E mRNA CTD PMID:25086211 NCBI chr 7:120,651,976...120,675,559
Ensembl chr 7:120,651,881...120,672,359 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 decreases expression ISO ferric oxide analog results in decreased expression of CX3CR1 mRNA CTD PMID:25086211 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO ferric oxide analog results in increased expression of CXCR4 mRNA CTD PMID:25086211 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP ferric oxide promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A1 protein]; ferric oxide promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA] CTD PMID:15211619 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
decreases expression		 ISO ferric oxide analog results in increased expression of DDIT3 mRNA; ferric oxide analog results in increased expression of DDIT3 protein
ferric oxide analog results in decreased expression of DDIT3 mRNA		 CTD PMID:24525745 PMID:25086211 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 decreases expression ISO ferric oxide analog results in decreased expression of DDIT4 mRNA CTD PMID:24525745 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382 		JBrowse link
G Dgkg diacylglycerol kinase, gamma decreases expression ISO ferric oxide analog results in decreased expression of DGKG mRNA CTD PMID:25086211 NCBI chr11:81,971,585...82,165,111
Ensembl chr11:81,972,219...82,163,165 		JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression ISO ferric oxide analog results in decreased expression of DUSP1 mRNA CTD PMID:25086211 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418 		JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO ferric oxide analog results in increased expression of DUSP4 mRNA CTD PMID:25086211 NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 decreases expression ISO ferric oxide analog results in decreased expression of EEF1A1 mRNA CTD PMID:25086211 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818 		JBrowse link
G Egfr epidermal growth factor receptor increases phosphorylation ISO ferric oxide analog results in increased phosphorylation of EGFR protein CTD PMID:24068039 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Egr1 early growth response 1 decreases expression ISO ferric oxide analog results in decreased expression of EGR1 mRNA CTD PMID:25086211 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429 		JBrowse link
G Egr2 early growth response 2 increases expression ISO ferric oxide analog results in increased expression of EGR2 mRNA CTD PMID:24525745 PMID:25086211 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 decreases expression ISO ferric oxide analog results in decreased expression of EIF2AK2 mRNA CTD PMID:25086211 NCBI chr 6:1,428,845...1,466,193
Ensembl chr 6:1,428,834...1,466,201 		JBrowse link
G Eno2 enolase 2 increases expression
decreases expression		 ISO ferric oxide analog results in increased expression of ENO2 mRNA
ferric oxide analog results in decreased expression of ENO2 mRNA		 CTD PMID:24525745 PMID:25086211 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047 		JBrowse link
G Epn2 epsin 2 increases expression ISO ferric oxide analog results in increased expression of EPN2 mRNA CTD PMID:25086211 NCBI chr10:47,795,496...47,857,373
Ensembl chr10:47,795,524...47,857,326 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO ferric oxide analog results in increased expression of and results in increased phosphorylation of ERN1 protein CTD PMID:25086211 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914 		JBrowse link
G Fam214a family with sequence similarity 214, member A increases expression ISO ferric oxide analog results in increased expression of FAM214A mRNA CTD PMID:25086211 NCBI chr 8:81,863,619...81,941,548
Ensembl chr 8:81,863,619...81,941,536 		JBrowse link
G Fblim1 filamin binding LIM protein 1 increases expression ISO ferric oxide analog results in increased expression of FBLIM1 mRNA CTD PMID:25086211 NCBI chr 5:160,122,466...160,158,921
Ensembl chr 5:160,122,425...160,158,386 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
increases expression		 ISO ferric oxide analog results in decreased expression of FOS mRNA
ferric oxide analog results in increased expression of FOS mRNA		 CTD PMID:24525745 PMID:25086211 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Fus FUS RNA binding protein decreases expression ISO ferric oxide analog results in decreased expression of FUS mRNA CTD PMID:25086211 NCBI chr 1:199,412,805...199,426,705
Ensembl chr 1:199,412,834...199,426,702 		JBrowse link
G Fyb1 FYN binding protein 1 decreases expression ISO ferric oxide analog results in decreased expression of FYB mRNA CTD PMID:25086211 NCBI chr 2:55,834,904...55,983,805
Ensembl chr 2:55,835,151...55,983,804 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases phosphorylation EXP ferric oxide analog results in increased phosphorylation of GADD45A protein CTD PMID:22995439 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO ferric oxide analog results in increased expression of GADD45B mRNA CTD PMID:25086211 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322 		JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO ferric oxide analog results in increased expression of GJA1 mRNA CTD PMID:25086211 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089 		JBrowse link
G Gpr183 G protein-coupled receptor 183 increases expression ISO ferric oxide analog results in increased expression of GPR183 mRNA CTD PMID:24525745 NCBI chr15:108,364,701...108,376,221
Ensembl chr15:108,364,701...108,376,221 		JBrowse link
G Gpr84 G protein-coupled receptor 84 decreases expression
increases expression		 ISO ferric oxide analog results in decreased expression of GPR84 mRNA
ferric oxide analog results in increased expression of GPR84 mRNA		 CTD PMID:24525745 PMID:25086211 NCBI chr 7:144,934,606...144,937,194
Ensembl chr 7:144,934,610...144,936,803 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [Benzo(a)pyrene co-treated with ferric oxide] results in increased activity of GSR protein CTD PMID:11033230 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361 		JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression		 ISO Oxygen deficiency inhibits the reaction [ferric oxide analog results in increased expression of H2AX protein] CTD PMID:27270449 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981 		JBrowse link
G H2bc9 H2B clustered histone 9 decreases expression ISO ferric oxide analog results in decreased expression of H2BC9 mRNA CTD PMID:24525745 PMID:25086211 NCBI chr17:44,519,815...44,520,269
Ensembl chr17:44,519,860...44,520,240 		JBrowse link
G H3c1 H3 clustered histone 1 decreases expression ISO ferric oxide analog results in decreased expression of H3C1 mRNA CTD PMID:25086211 NCBI chr17:43,616,206...43,616,735
Ensembl chr17:44,839,721...44,840,131
Ensembl chr17:44,839,721...44,840,131
Ensembl chr17:44,839,721...44,840,131
Ensembl chr17:44,839,721...44,840,131 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO ferric oxide analog results in increased expression of HBEGF mRNA CTD PMID:25086211 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403 		JBrowse link
G Heatr3 HEAT repeat containing 3 decreases expression ISO ferric oxide analog results in decreased expression of HEATR3 mRNA CTD PMID:25086211 NCBI chr19:19,858,419...19,896,782
Ensembl chr19:19,858,416...19,896,421 		JBrowse link
G Hebp1 heme binding protein 1 increases expression ISO ferric oxide analog results in increased expression of HEBP1 mRNA CTD PMID:25086211 NCBI chr 4:168,903,586...168,933,102
Ensembl chr 4:168,903,565...168,933,079 		JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated increases expression ISO ferric oxide analog results in increased expression of HILPDA mRNA CTD PMID:25086211 NCBI chr 4:56,547,600...56,550,584
Ensembl chr 4:56,549,739...56,549,993 		JBrowse link
G Hist1h2ail1 histone cluster 1 H2a family member I like 1 decreases expression ISO ferric oxide analog results in decreased expression of H3C6 mRNA CTD PMID:25086211 NCBI chr17:43,814,773...43,815,183
Ensembl chr17:43,814,773...43,815,183
Ensembl chr17:43,814,773...43,815,183 		JBrowse link
G Hist1h2bq histone cluster 1 H2B family member Q decreases expression ISO ferric oxide analog results in decreased expression of H2BC7 mRNA CTD PMID:24525745 PMID:25086211 NCBI chr17:43,679,925...43,689,311
Ensembl chr17:43,679,925...43,689,311 		JBrowse link
G Hist2h2be histone cluster 2 H2B family member E decreases expression
increases expression		 ISO ferric oxide analog results in decreased expression of H2BC11 mRNA
ferric oxide analog results in increased expression of H2BC21 mRNA		 CTD PMID:25086211 NCBI chr 2:198,360,837...198,363,399
Ensembl chr 2:198,360,998...198,361,378 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO ferric oxide analog results in increased expression of HMOX1 mRNA CTD PMID:24525745 PMID:25086211 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 increases expression ISO ferric oxide analog results in increased expression of HSD3B7 mRNA CTD PMID:25086211 NCBI chr 1:199,248,084...199,251,745
Ensembl chr 1:199,248,470...199,251,740 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of HSPA1A mRNA CTD PMID:20540983 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of HSPA8 mRNA CTD PMID:20540983 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO ferric oxide results in decreased expression of HSPD1 protein CTD PMID:28077287 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956 		JBrowse link
G Hyal1 hyaluronidase 1 increases expression
decreases expression		 ISO ferric oxide analog results in increased expression of HYAL1 mRNA
ferric oxide analog results in decreased expression of HYAL1 mRNA		 CTD PMID:24525745 PMID:25086211 NCBI chr 8:116,332,834...116,337,522
Ensembl chr 8:116,332,796...116,335,435 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO ferric oxide results in increased expression of ICAM1 protein CTD PMID:21439359 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Icam2 intercellular adhesion molecule 2 decreases expression ISO ferric oxide analog results in decreased expression of ICAM2 mRNA CTD PMID:25086211 NCBI chr10:94,569,889...94,581,218
Ensembl chr10:94,569,890...94,576,512 		JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO ferric oxide analog results in increased expression of ID1 mRNA CTD PMID:24525745 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718 		JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein increases expression ISO ferric oxide analog results in increased expression of ID3 mRNA CTD PMID:24525745 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha decreases expression ISO ferric oxide analog results in decreased expression of IL10RA mRNA CTD PMID:25086211 NCBI chr 8:49,558,062...49,573,891
Ensembl chr 8:49,560,035...49,573,742 		JBrowse link
G Il1b interleukin 1 beta increases secretion ISO ferric oxide analog results in increased secretion of IL1B protein
ferric oxide results in increased secretion of IL1B protein		 CTD PMID:24525745 PMID:24885771 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of IL2 protein CTD PMID:20540983 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of IL4 protein; ferric oxide inhibits the reaction [Ovalbumin results in increased expression of IL4 protein] CTD PMID:20540983 PMID:23147377 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Il5 interleukin 5 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of IL5 protein CTD PMID:20540983 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion		 ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of IL6 protein
ferric oxide results in increased secretion of IL6 protein
ferric oxide analog results in increased secretion of IL6 protein		 CTD PMID:20540983 PMID:24525745 PMID:24885771 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression ISO ferric oxide analog results in decreased expression of IRF7 mRNA CTD PMID:25086211 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation EXP ferric oxide analog results in increased phosphorylation of JUN protein CTD PMID:22995439 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277 		JBrowse link
G Klf2 Kruppel-like factor 2 decreases expression ISO ferric oxide analog results in decreased expression of KLF2 mRNA CTD PMID:25086211 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037 		JBrowse link
G Klf4 Kruppel like factor 4 decreases expression ISO ferric oxide analog results in decreased expression of KLF4 mRNA CTD PMID:25086211 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions EXP [ferric oxide analog co-treated with Acrolein] results in decreased expression of LAMP1 protein CTD PMID:24847785 NCBI chr16:81,689,576...81,714,341
Ensembl chr16:81,689,335...81,714,419 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 increases expression ISO ferric oxide analog results in increased expression of LAMP2 protein CTD PMID:25086211 NCBI chr  X:124,722,628...124,766,079
Ensembl chr  X:124,722,628...124,766,044 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 decreases expression ISO ferric oxide analog results in decreased expression of LILR4B mRNA CTD PMID:24525745 NCBI chr 1:73,393,854...73,399,448
Ensembl chr 1:73,393,850...73,399,579 		JBrowse link
G Lima1 LIM domain and actin binding 1 increases expression ISO ferric oxide analog results in increased expression of LIMA1 mRNA CTD PMID:25086211 NCBI chr 7:141,428,113...141,528,447
Ensembl chr 7:141,428,063...141,528,397 		JBrowse link
G Lims2 LIM zinc finger domain containing 2 increases expression ISO ferric oxide analog results in increased expression of LIMS2 mRNA CTD PMID:25086211 NCBI chr18:24,707,951...24,746,159
Ensembl chr18:24,708,115...24,746,159 		JBrowse link
G Lst1 leukocyte specific transcript 1 decreases expression ISO ferric oxide analog results in decreased expression of LST1 mRNA CTD PMID:24525745 NCBI chr20:5,175,213...5,179,352
Ensembl chr20:5,176,016...5,179,263 		JBrowse link
G Lyz2 lysozyme 2 decreases expression ISO ferric oxide analog results in decreased expression of LYZ2 mRNA CTD PMID:25086211 NCBI chr 7:60,335,968...60,341,264
Ensembl chr 7:60,335,969...60,341,264 		JBrowse link
G Mafb MAF bZIP transcription factor B increases expression ISO ferric oxide analog results in increased expression of MAFB mRNA CTD PMID:24525745 NCBI chr 3:156,338,993...156,340,913
Ensembl chr 3:156,339,004...156,340,913 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha increases expression ISO ferric oxide analog results in increased expression of MAP1LC3A protein CTD PMID:25086211 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO ferric oxide analog results in increased expression of MAP1LC3B protein CTD PMID:24068039 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions		 ISO
EXP		 ferric oxide analog results in increased phosphorylation of MAPK1 protein
[ferric oxide analog co-treated with Acrolein] results in increased phosphorylation of MAPK1 protein		 CTD PMID:24068039 PMID:24847785 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions		 ISO
EXP		 ferric oxide analog results in increased phosphorylation of MAPK3 protein
[ferric oxide analog co-treated with Acrolein] results in increased phosphorylation of MAPK3 protein		 CTD PMID:24068039 PMID:24847785 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression
increases expression		 ISO ferric oxide analog results in decreased expression of MAT2A mRNA
ferric oxide analog results in increased expression of MAT2A mRNA		 CTD PMID:24525745 PMID:25086211 NCBI chr 4:100,297,478...100,303,047
Ensembl chr 4:100,296,075...100,303,080 		JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression ISO ferric oxide analog results in decreased expression of MEF2C mRNA CTD PMID:25086211 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787 		JBrowse link
G Mmp12 matrix metallopeptidase 12 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of MMP12 mRNA CTD PMID:20540983 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493 		JBrowse link
G Mmp19 matrix metallopeptidase 19 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of MMP19 mRNA CTD PMID:20540983 NCBI chr 7:3,216,392...3,224,202
Ensembl chr 7:3,216,497...3,224,201 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of MMP2 mRNA CTD PMID:20540983 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611 		JBrowse link
G Mmp23 matrix metallopeptidase 23 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of MMP23 mRNA CTD PMID:20540983 NCBI chr 5:173,078,811...173,082,834
Ensembl chr 5:173,078,590...173,081,839 		JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression ISO ferric oxide results in increased expression of MMP7 protein CTD PMID:24885771 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049 		JBrowse link
G Msmb microseminoprotein, beta affects expression ISO ferric oxide affects the expression of MSMB mRNA CTD PMID:28077287 NCBI chr16:8,280,275...8,300,853
Ensembl chr16:8,280,275...8,300,852 		JBrowse link
G Naa80 N(alpha)-acetyltransferase 80, NatH catalytic subunit increases expression ISO ferric oxide analog results in increased expression of NAA80 mRNA CTD PMID:25086211 NCBI chr 8:116,336,441...116,339,691
Ensembl chr 8:116,336,441...116,339,690 		JBrowse link
G Nckap5l NCK-associated protein 5-like decreases expression ISO ferric oxide analog results in decreased expression of NCKAP5L mRNA CTD PMID:24525745 NCBI chr 7:141,081,943...141,093,924
Ensembl chr 7:141,081,943...141,095,691 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO ferric oxide analog results in increased expression of NDRG1 mRNA CTD PMID:25086211 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 increases expression ISO ferric oxide analog results in increased expression of NEDD9 mRNA CTD PMID:24525745 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701 		JBrowse link
G Nox4 NADPH oxidase 4 increases expression ISO ferric oxide results in increased expression of NOX4 protein CTD PMID:28077287 PMID:28993115 NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194 		JBrowse link
G Npm3 nucleophosmin/nucleoplasmin, 3 decreases expression ISO ferric oxide analog results in decreased expression of NPM3 mRNA CTD PMID:25086211 NCBI chr 1:265,504,105...265,506,080
Ensembl chr 1:265,504,575...265,506,046 		JBrowse link
G Nrp1 neuropilin 1 decreases expression ISO ferric oxide analog results in decreased expression of NRP1 mRNA CTD PMID:25086211 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858 		JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II increases expression ISO ferric oxide analog results in increased expression of NT5C2 mRNA CTD PMID:24525745 NCBI chr 1:266,652,966...266,782,935
Ensembl chr 1:266,659,519...266,782,910 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator decreases expression ISO ferric oxide analog results in decreased expression of NUPR1 mRNA CTD PMID:24525745 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524 		JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 decreases expression ISO ferric oxide analog results in decreased expression of OAS2 mRNA CTD PMID:25086211 NCBI chr12:41,341,417...41,363,124
Ensembl chr12:41,340,815...41,363,161 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like decreases expression ISO ferric oxide analog results in decreased expression of OASL1 mRNA CTD PMID:25086211 NCBI chr12:47,444,138...47,456,680
Ensembl chr12:47,444,104...47,456,894 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions		 ISO ferric oxide analog results in increased cleavage of PARP1 protein
ferric oxide results in decreased expression of and results in increased cleavage of PARP1 protein
ferric oxide results in increased cleavage of PARP1 protein		 CTD PMID:26991130 PMID:27270449 PMID:28993115 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Pate4 prostate and testis expressed 4 affects expression ISO ferric oxide affects the expression of PATE4 mRNA CTD PMID:28077287 NCBI chr 8:36,815,007...36,817,747
Ensembl chr 8:36,815,007...36,817,747 		JBrowse link
G Pcdh7 protocadherin 7 decreases expression ISO ferric oxide analog results in decreased expression of PCDH7 mRNA CTD PMID:25086211 NCBI chr14:54,649,054...55,081,632
Ensembl chr14:55,072,200...55,081,551 		JBrowse link
G Per2 period circadian regulator 2 increases expression ISO ferric oxide analog results in increased expression of PER2 mRNA CTD PMID:25086211 NCBI chr 9:98,555,154...98,597,362
Ensembl chr 9:98,555,169...98,597,359 		JBrowse link
G Pes1 pescadillo ribosomal biogenesis factor 1 decreases expression ISO ferric oxide analog results in decreased expression of PES1 mRNA CTD PMID:25086211 NCBI chr14:84,211,600...84,227,980
Ensembl chr14:84,211,600...84,227,978 		JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO ferric oxide analog results in increased expression of PHLDA1 mRNA CTD PMID:25086211 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664 		JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 increases expression ISO ferric oxide analog results in increased expression of PLEKHF1 mRNA CTD PMID:25086211 NCBI chr 1:94,609,041...94,616,565
Ensembl chr 1:94,609,377...94,610,854 		JBrowse link
G Plk2 polo-like kinase 2 increases expression ISO ferric oxide analog results in increased expression of PLK2 mRNA CTD PMID:25086211 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901 		JBrowse link
G Plk3 polo-like kinase 3 increases expression ISO ferric oxide analog results in increased expression of PLK3 mRNA CTD PMID:25086211 NCBI chr 5:135,997,725...136,002,900
Ensembl chr 5:135,997,725...136,002,900 		JBrowse link
G Plpbp pyridoxal phosphate binding protein increases expression ISO ferric oxide analog results in increased expression of PLPBP mRNA CTD PMID:25086211 NCBI chr16:69,164,654...69,176,245
Ensembl chr16:69,163,577...69,176,036 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A decreases expression ISO ferric oxide analog results in decreased expression of PPP1R15A mRNA CTD PMID:24525745 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974 		JBrowse link
G Prf1 perforin 1 decreases expression ISO ferric oxide analog results in decreased expression of PRF1 mRNA CTD PMID:24525745 NCBI chr20:30,915,294...30,920,804
Ensembl chr20:30,915,213...30,921,382 		JBrowse link
G Prmt6 protein arginine methyltransferase 6 decreases expression ISO ferric oxide analog results in decreased expression of PRMT6 mRNA CTD PMID:25086211 NCBI chr 2:213,173,403...213,180,721
Ensembl chr 2:213,173,403...213,178,632
Ensembl chr 2:213,173,403...213,178,632 		JBrowse link
G Prr18 proline rich 18 increases expression ISO ferric oxide analog results in increased expression of PRR18 mRNA CTD PMID:25086211 NCBI chr 1:52,989,076...52,994,843
Ensembl chr 1:52,991,287...52,992,213 		JBrowse link
G Prr33 proline rich 33 decreases expression ISO ferric oxide analog results in decreased expression of PRR33 mRNA CTD PMID:25086211 NCBI chr 1:215,658,996...215,666,512
Ensembl chr 1:215,659,713...215,660,492 		JBrowse link
G Rab15 RAB15, member RAS oncogene family increases expression ISO ferric oxide analog results in increased expression of RAB15 mRNA CTD PMID:25086211 NCBI chr 6:99,845,952...99,870,320
Ensembl chr 6:99,845,954...99,870,024 		JBrowse link
G Rad50 RAD50 double strand break repair protein decreases expression ISO ferric oxide analog results in decreased expression of RAD50 mRNA CTD PMID:24525745 NCBI chr10:39,002,130...39,054,042
Ensembl chr10:39,001,498...39,054,142 		JBrowse link
G Rbak RB-associated KRAB zinc finger increases expression ISO ferric oxide analog results in increased expression of RBAK mRNA CTD PMID:24525745 NCBI chr12:13,428,648...13,442,279
Ensembl chr12:13,428,685...13,442,286 		JBrowse link
G Rcan1 regulator of calcineurin 1 increases expression ISO ferric oxide analog results in increased expression of RCAN1 mRNA CTD PMID:25086211 NCBI chr11:32,539,689...32,620,274
Ensembl chr11:32,539,683...32,550,539 		JBrowse link
G Rcbtb2 RCC1 and BTB domain containing protein 2 increases expression ISO ferric oxide analog results in increased expression of RCBTB2 mRNA CTD PMID:24525745 NCBI chr15:55,029,388...55,074,728
Ensembl chr15:55,034,033...55,073,437 		JBrowse link
G Rilpl1 Rab interacting lysosomal protein-like 1 decreases expression ISO ferric oxide analog results in decreased expression of RILPL1 mRNA CTD PMID:24525745 NCBI chr12:37,490,320...37,528,393
Ensembl chr12:37,490,584...37,528,784 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions EXP [ferric oxide analog co-treated with Acrolein] results in increased expression of RIPK1 protein CTD PMID:24847785 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions EXP [ferric oxide analog co-treated with Acrolein] results in increased expression of RIPK3 protein CTD PMID:24847785 NCBI chr15:34,470,796...34,479,741
Ensembl chr15:34,470,796...34,479,741 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of H2-EB1 mRNA CTD PMID:20540983 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190 		JBrowse link
G RT1-S3 RT1 class Ib, locus S3 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of H2-T23 mRNA CTD PMID:20540983 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818 		JBrowse link
G Rusc2 RUN and SH3 domain containing 2 increases expression ISO ferric oxide analog results in increased expression of RUSC2 mRNA CTD PMID:25086211 NCBI chr 5:58,860,444...58,883,152
Ensembl chr 5:58,855,773...58,882,096 		JBrowse link
G Samd9 sterile alpha motif domain containing 9 decreases expression ISO ferric oxide analog results in decreased expression of SAMD9L mRNA CTD PMID:25086211 NCBI chr 4:28,304,967...28,324,637
Ensembl chr 4:28,305,002...28,310,178 		JBrowse link
G Serpinb1a serpin family B member 1A decreases expression ISO ferric oxide analog results in decreased expression of SERPINB1A mRNA CTD PMID:24525745 NCBI chr17:32,903,089...32,911,498
Ensembl chr17:32,904,119...32,911,495 		JBrowse link
G Skil SKI-like proto-oncogene increases expression ISO ferric oxide analog results in increased expression of SKIL mRNA CTD PMID:24525745 NCBI chr 2:115,862,932...115,891,304
Ensembl chr 2:115,866,701...115,891,097 		JBrowse link
G Slamf8 SLAM family member 8 increases expression ISO ferric oxide analog results in increased expression of SLAMF8 mRNA CTD PMID:24525745 NCBI chr13:90,967,862...90,978,752
Ensembl chr13:90,967,739...90,977,734 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 increases expression ISO ferric oxide analog results in increased expression of SLC11A1 mRNA CTD PMID:25086211 NCBI chr 9:81,655,590...81,666,697
Ensembl chr 9:81,655,629...81,666,706 		JBrowse link
G Slc46a3 solute carrier family 46, member 3 decreases expression ISO ferric oxide analog results in decreased expression of SLC46A3 mRNA CTD PMID:25086211 NCBI chr12:8,725,479...8,741,944
Ensembl chr12:8,725,517...8,741,951 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of SLPI mRNA CTD PMID:20540983 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO ferric oxide analog results in increased expression of SOD1 protein CTD PMID:24068039 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO ferric oxide analog results in increased expression of SOD2 protein; ferric oxide results in increased expression of SOD2 protein CTD PMID:24068039 PMID:25086211 PMID:26991130 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Spata24 spermatogenesis associated 24 decreases expression ISO ferric oxide analog results in decreased expression of SPATA24 mRNA CTD PMID:24525745 NCBI chr18:28,446,592...28,454,724
Ensembl chr18:28,446,589...28,454,756 		JBrowse link
G Tatdn2 TatD DNase domain containing 2 decreases expression ISO ferric oxide analog results in decreased expression of TATDN2 mRNA CTD PMID:24525745 NCBI chr 4:145,653,299...145,669,343
Ensembl chr 4:145,653,602...145,669,343 		JBrowse link
G Tbc1d2 TBC1 domain family, member 2 increases expression
decreases expression		 ISO ferric oxide analog results in increased expression of TBC1D2 mRNA
ferric oxide analog results in decreased expression of TBC1D2 mRNA		 CTD PMID:24525745 PMID:25086211 NCBI chr 5:62,213,001...62,261,467
Ensembl chr 5:62,212,982...62,260,105 		JBrowse link
G Tbxas1 thromboxane A synthase 1 increases expression ISO ferric oxide analog results in increased expression of TBXAS1 mRNA CTD PMID:24525745 NCBI chr 4:66,624,181...66,846,745
Ensembl chr 4:66,670,618...66,846,805 		JBrowse link
G Tf transferrin increases expression EXP ferric oxide results in increased expression of TF mRNA CTD PMID:16428268 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333 		JBrowse link
G Tfrc transferrin receptor decreases expression ISO ferric oxide analog results in decreased expression of TFRC mRNA CTD PMID:25086211 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223 		JBrowse link
G Tgfbi transforming growth factor, beta induced increases expression ISO ferric oxide analog results in increased expression of TGFBI mRNA CTD PMID:24525745 NCBI chr17:8,400,123...8,429,338
Ensembl chr17:8,400,146...8,429,338 		JBrowse link
G Tgm2 transglutaminase 2 increases expression ISO ferric oxide analog results in increased expression of TGM2 mRNA CTD PMID:25086211 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of TIMP1 mRNA CTD PMID:20540983 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO ferric oxide results in increased expression of TIMP2 protein CTD PMID:24885771 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072 		JBrowse link
G Tlr2 toll-like receptor 2 increases expression ISO ferric oxide analog results in increased expression of TLR2 mRNA CTD PMID:24525745 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061 		JBrowse link
G Tmem176a transmembrane protein 176A decreases expression ISO ferric oxide analog results in decreased expression of TMEM176A mRNA CTD PMID:25086211 NCBI chr 4:78,458,735...78,462,415
Ensembl chr 4:78,458,625...78,462,423 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases secretion		 ISO [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of TNF protein
ferric oxide results in increased secretion of TNF protein
ferric oxide analog results in increased secretion of TNF protein		 CTD PMID:20540983 PMID:24068039 PMID:24525745 PMID:24885771 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnni3 troponin I3, cardiac type increases expression ISO ferric oxide results in increased expression of TNNI3 protein CTD PMID:28993115 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488 		JBrowse link
G Tp53 tumor protein p53 increases phosphorylation
multiple interactions		 EXP ferric oxide analog results in increased phosphorylation of TP53 protein
[ferric oxide analog co-treated with Acrolein] results in increased expression of TP53 protein		 CTD PMID:22995439 PMID:24847785 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO ferric oxide analog results in increased expression of TRP53INP1 mRNA CTD PMID:25086211 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein decreases expression ISO ferric oxide analog results in decreased expression of TPR mRNA CTD PMID:24525745 NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827 		JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression ISO ferric oxide analog results in decreased expression of TRIB3 mRNA CTD PMID:24525745 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571 		JBrowse link
G Ttpal alpha tocopherol transfer protein like decreases expression ISO ferric oxide analog results in decreased expression of TTPAL mRNA CTD PMID:25086211 NCBI chr 3:159,995,013...160,015,314
Ensembl chr 3:159,995,064...160,013,274 		JBrowse link
G Tubb2b tubulin, beta 2B class IIb increases expression ISO ferric oxide analog results in increased expression of TUBB2B mRNA CTD PMID:24525745 NCBI chr17:31,441,640...31,444,687
Ensembl chr17:31,441,630...31,482,759 		JBrowse link
G Wdfy3 WD repeat and FYVE domain containing 3 increases expression ISO ferric oxide analog results in increased expression of WDFY3 mRNA CTD PMID:24525745 NCBI chr14:9,169,409...9,384,835
Ensembl chr14:9,141,512...9,381,870 		JBrowse link
G Yipf7 Yip1 domain family, member 7 increases expression ISO ferric oxide analog results in increased expression of YIPF7 mRNA CTD PMID:25086211 NCBI chr14:62,565,369...62,609,529
Ensembl chr14:62,567,745...62,595,854 		JBrowse link
G Zbtb2 zinc finger and BTB domain containing 2 decreases expression ISO ferric oxide analog results in decreased expression of ZBTB2 mRNA CTD PMID:24525745 NCBI chr 1:40,914,175...40,933,586
Ensembl chr 1:40,914,171...40,921,508 		JBrowse link
G Zc3h13 zinc finger CCCH type containing 13 increases expression ISO ferric oxide analog results in increased expression of ZC3H13 mRNA CTD PMID:24525745 NCBI chr15:57,340,522...57,405,287
Ensembl chr15:57,340,579...57,405,287 		JBrowse link
G Zfp36 zinc finger protein 36 increases expression ISO ferric oxide analog results in increased expression of ZFP36 mRNA CTD PMID:24525745 NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569 		JBrowse link
ferrosoferric oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in increased expression of BAX protein CTD PMID:30098274 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in decreased expression of BCL2 protein CTD PMID:30098274 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in increased cleavage of CASP3 protein; [Methotrexate co-treated with [Ferrosoferric Oxide binds to polylactide-polyethylene glycol-polylactide]] results in increased expression of CASP3 mRNA; [Methotrexate co-treated with [Ferrosoferric Oxide binds to polylactide-polyethylene glycol-polylactide]] results in increased expression of CASP3 protein modified form CTD PMID:24935781 PMID:30098274 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in increased cleavage of CASP9 protein CTD PMID:30098274 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Fadd Fas associated via death domain multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in decreased expression of FADD protein CTD PMID:30098274 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in increased expression of FAS protein CTD PMID:30098274 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in increased expression of FOS protein CTD PMID:30098274 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in decreased expression of HMOX1 protein CTD PMID:30098274 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Il1b interleukin 1 beta increases secretion EXP
ISO		 Ferrosoferric Oxide analog results in increased secretion of IL1B protein
Ferrosoferric Oxide results in increased secretion of IL1B protein		 CTD PMID:22939914 PMID:24885771 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il6 interleukin 6 increases secretion EXP
ISO		 Ferrosoferric Oxide analog results in increased secretion of IL6 protein
Ferrosoferric Oxide results in increased secretion of IL6 protein		 CTD PMID:22939914 PMID:24885771 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in increased expression of JUN protein CTD PMID:30098274 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in increased phosphorylation of MAPK1 protein CTD PMID:30098274 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in increased phosphorylation of MAPK3 protein CTD PMID:30098274 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in increased phosphorylation of MAPK8 protein CTD PMID:30098274 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in increased phosphorylation of MAPK9 protein CTD PMID:30098274 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in increased expression of NQO1 protein CTD PMID:30098274 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in decreased expression of PARP1 protein CTD PMID:30098274 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in increased expression of PTGS2 protein CTD PMID:30098274 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Rras RAS related multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in increased expression of RRAS protein CTD PMID:30098274 NCBI chr 1:101,012,822...101,016,720
Ensembl chr 1:101,012,822...101,016,720 		JBrowse link
G Tnf tumor necrosis factor increases secretion EXP Ferrosoferric Oxide analog results in increased secretion of TNF protein CTD PMID:22939914 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Ferrosoferric Oxide binds to titanium dioxide] which results in increased expression of TP53 protein CTD PMID:30098274 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
ferrous oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO bromotetrandrine promotes the reaction [[ferric oxide co-treated with ferrous oxide co-treated with Daunorubicin] results in increased expression of BAX protein] CTD PMID:19421372 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO bromotetrandrine promotes the reaction [[ferric oxide co-treated with ferrous oxide co-treated with Daunorubicin] results in increased expression of CASP3 protein] CTD PMID:19421372 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO ferrous oxide results in increased expression of ICAM1 protein CTD PMID:21439359 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19840
    chemical entity 19840
      molecular entity 19838
        transition element molecular entity 16434
          iron group molecular entity 852
            iron molecular entity 837
              iron oxide 203
                ferric oxide + 195
                ferrosoferric oxide + 21
                ferrous oxide 3
                iron oxide mineral + 0
                iron oxide nanoparticle + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19840
    subatomic particle 19838
      composite particle 19838
        hadron 19838
          baryon 19838
            nucleon 19838
              atomic nucleus 19838
                atom 19838
                  metal atom 17288
                    transition element atom 16747
                      d-block element atom 16738
                        iron group element atom 859
                          iron group molecular entity 852
                            iron molecular entity 837
                              iron oxide 203
                                ferric oxide + 195
                                ferrosoferric oxide + 21
                                ferrous oxide 3
                                iron oxide mineral + 0
                                iron oxide nanoparticle + 0
paths to the root