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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:benzatropine
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Accession:CHEBI:3048 term browser browse the term
Definition:Tropane in which a hydrogen at position 3 is substituted by a diphenylmethoxy group (endo-isomer). An acetylcholine receptor antagonist, it is used (particularly as its methanesulphonate salt) in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments.
Synonyms:exact_synonym: (3-endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane
 related_synonym: 3alpha-(diphenylmethoxy)-1alphaH,5alphaH-tropane;   3alpha-(diphenylmethoxy)tropane;   3alpha-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane;   3endo-benzhydryloxytropane;   Benztropine;   Formula=C21H25NO;   InChI=1S/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19+,20+;   InChIKey=GIJXKZJWITVLHI-PMOLBWCYSA-N;   SMILES=[H][C@]1(C[C@]2([H])CC[C@]([H])(C1)N2C)OC(c1ccccc1)c1ccccc1;   benzatropina;   benzatropinum;   benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether;   tropine benzohydryl ether
 alt_id: CHEBI:661238
 xref: Beilstein:90688;   CAS:86-13-5;   DrugBank:DB00245;   Drug_Central:333;   KEGG:C06846;   KEGG:D07511
 xref_mesh: MESH:D001590
 xref: Patent:US2595405;   Wikipedia:Benzatropine


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benzatropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Benztropine results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO Benztropine results in increased expression of ACOT2 protein CTD PMID:34122009 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245 		JBrowse link
G Actbl2 actin, beta-like 2 increases expression ISO Benztropine results in increased expression of ACTBL2 protein CTD PMID:34122009 NCBI chr 2:42,858,020...42,860,767
Ensembl chr 2:42,858,020...42,860,767 		JBrowse link
G Actr1a actin related protein 1A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of ACTR1A protein CTD PMID:34122009 NCBI chr 1:245,237,821...245,256,618
Ensembl chr 1:245,237,826...245,256,495 		JBrowse link
G Actr3 actin related protein 3 decreases expression ISO Benztropine results in decreased expression of ACTR3 protein CTD PMID:34122009 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Adsl adenylosuccinate lyase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of ADSL protein CTD PMID:34122009 NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760 		JBrowse link
G Agps alkylglycerone phosphate synthase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of AGPS protein CTD PMID:34122009 NCBI chr 3:60,747,323...60,845,831
Ensembl chr 3:60,747,323...60,845,830 		JBrowse link
G Ak1 adenylate kinase 1 decreases expression ISO Benztropine results in decreased expression of AK1 protein CTD PMID:34122009 NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041 		JBrowse link
G Anxa1 annexin A1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of ANXA1 protein CTD PMID:34122009 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Anxa5 annexin A5 decreases expression ISO Benztropine results in decreased expression of ANXA5 protein CTD PMID:34122009 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Anxa6 annexin A6 decreases expression ISO Benztropine results in decreased expression of ANXA6 protein CTD PMID:34122009 NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433 		JBrowse link
G Anxa7 annexin A7 increases expression ISO Benztropine results in increased expression of ANXA7 protein CTD PMID:34122009 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385 		JBrowse link
G Armt1 acidic residue methyltransferase 1 increases expression ISO Benztropine results in increased expression of ARMT1 protein CTD PMID:34122009 NCBI chr 1:40,894,558...40,918,302
Ensembl chr 1:40,894,550...40,918,302 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Benztropine results in decreased expression of ASNS protein CTD PMID:34122009 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Asph aspartate-beta-hydroxylase increases expression ISO Benztropine results in increased expression of ASPH protein CTD PMID:34122009 NCBI chr 5:22,601,581...22,814,107
Ensembl chr 5:22,603,486...22,813,876 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases expression ISO Benztropine results in increased expression of ATP2A3 protein CTD PMID:34122009 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748 		JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of ATP5F1C protein CTD PMID:34122009 NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 decreases expression ISO Benztropine results in decreased expression of ATP6V1B2 protein CTD PMID:34122009 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745 		JBrowse link
G Atxn10 ataxin 10 increases expression ISO Benztropine results in increased expression of ATXN10 protein CTD PMID:34122009 NCBI chr 7:116,441,768...116,565,093
Ensembl chr 7:116,441,613...116,565,087 		JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of BAZ1B protein CTD PMID:34122009 NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member decreases expression ISO Benztropine results in decreased expression of BCAR1 protein CTD PMID:34122009 NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907 		JBrowse link
G Bltp1 bridge-like lipid transfer protein family member 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of BLTP1 protein CTD PMID:34122009 NCBI chr 2:119,708,114...119,924,697
Ensembl chr 2:119,708,209...119,924,695 		JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Benztropine results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Brd2 bromodomain containing 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of BRD2 protein CTD PMID:34122009 NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388 		JBrowse link
G Bsg basigin decreases expression ISO Benztropine results in decreased expression of BSG protein CTD PMID:34122009 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Cald1 caldesmon 1 decreases expression
multiple interactions		 ISO Benztropine results in decreased expression of CALD1 protein
[Cuprizone co-treated with Benztropine] results in decreased expression of CALD1 protein		 CTD PMID:34122009 NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932 		JBrowse link
G Calu calumenin decreases expression ISO Benztropine results in decreased expression of CALU protein CTD PMID:34122009 NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of CAMK2D protein CTD PMID:34122009 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Caprin1 cell cycle associated protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CAPRIN1 protein CTD PMID:34122009 NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502 		JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CASP8AP2 protein CTD PMID:34122009 NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275 		JBrowse link
G Cbx5 chromobox 5 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of CBX5 protein CTD PMID:34122009 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022 		JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 increases expression ISO Benztropine results in increased expression of CCAR1 protein CTD PMID:34122009 NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526 		JBrowse link
G Ccdc121 coiled-coil domain containing 121 increases expression ISO Benztropine results in increased expression of CCDC121 protein CTD PMID:34122009 NCBI chr 6:24,970,845...24,973,451
Ensembl chr 6:24,970,833...24,973,478 		JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CCT6A protein CTD PMID:34122009 NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression ISO Benztropine results in decreased expression of CCT7 protein CTD PMID:34122009 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CCT8 protein CTD PMID:34122009 NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079 		JBrowse link
G Cd276 Cd276 molecule decreases expression ISO Benztropine results in decreased expression of CD276 protein CTD PMID:34122009 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380 		JBrowse link
G Cenpv centromere protein V increases expression ISO Benztropine results in increased expression of CENPV protein CTD PMID:34122009 NCBI chr10:47,214,479...47,228,552
Ensembl chr10:47,214,490...47,228,761 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 decreases expression ISO Benztropine results in decreased expression of CHD4 protein CTD PMID:34122009 NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Ckb creatine kinase B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of CKB protein CTD PMID:34122009 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315 		JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase multiple interactions
decreases expression		 ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CNP protein
Benztropine results in decreased expression of CNP protein		 CTD PMID:34122009 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720 		JBrowse link
G Col14a1 collagen type XIV alpha 1 chain multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of COL14A1 protein CTD PMID:34122009 NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214 		JBrowse link
G Col5a2 collagen type V alpha 2 chain multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of COL5A2 protein CTD PMID:34122009 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Cops4 COP9 signalosome subunit 4 decreases expression ISO Benztropine results in decreased expression of COPS4 protein CTD PMID:34122009 NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887 		JBrowse link
G Coro1b coronin 1B decreases expression ISO Benztropine results in decreased expression of CORO1B protein CTD PMID:34122009 NCBI chr 1:201,442,977...201,448,416
Ensembl chr 1:201,443,014...201,448,416 		JBrowse link
G Coro7 coronin 7 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CORO7 protein CTD PMID:34122009 NCBI chr10:10,880,299...10,941,001
Ensembl chr10:10,885,196...10,941,001 		JBrowse link
G Cpne3 copine 3 decreases expression ISO Benztropine results in decreased expression of CPNE3 protein CTD PMID:34122009 NCBI chr 5:33,014,658...33,063,934
Ensembl chr 5:33,016,307...33,063,934 		JBrowse link
G Cpsf3 cleavage and polyadenylation specific factor 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CPSF3 protein CTD PMID:34122009 NCBI chr 6:40,836,121...40,864,129
Ensembl chr 6:40,836,097...40,864,128 		JBrowse link
G Crtap cartilage associated protein increases expression ISO Benztropine results in increased expression of CRTAP protein CTD PMID:34122009 NCBI chr 8:114,047,929...114,067,636
Ensembl chr 8:114,047,933...114,067,631 		JBrowse link
G Cryz crystallin zeta multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CRYZ protein CTD PMID:34122009 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Csde1 cold shock domain containing E1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CSDE1 protein CTD PMID:34122009 NCBI chr 2:190,546,015...190,582,787
Ensembl chr 2:190,554,980...190,582,784 		JBrowse link
G Cstf2 cleavage stimulation factor subunit 2 decreases expression ISO Benztropine results in decreased expression of CSTF2 protein CTD PMID:34122009 NCBI chr  X:97,253,559...97,279,476
Ensembl chr  X:97,253,586...97,279,476 		JBrowse link
G Ctbp1 C-terminal binding protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CTBP1 protein CTD PMID:34122009 NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821 		JBrowse link
G Cul2 cullin 2 increases expression ISO Benztropine results in increased expression of CUL2 protein CTD PMID:34122009 NCBI chr17:54,169,093...54,210,197
Ensembl chr17:54,169,086...54,209,968 		JBrowse link
G Cul4b cullin 4B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CUL4B protein CTD PMID:34122009 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688 		JBrowse link
G Dars2 aspartyl-tRNA synthetase 2 (mitochondrial) multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of DARS2 protein CTD PMID:34122009 NCBI chr13:73,308,726...73,336,558
Ensembl chr13:73,308,726...73,336,934 		JBrowse link
G Dazap1 DAZ associated protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of DAZAP1 protein CTD PMID:34122009 NCBI chr 7:9,423,673...9,448,116
Ensembl chr 7:9,424,178...9,538,818 		JBrowse link
G Dctn2 dynactin subunit 2 increases expression ISO Benztropine results in increased expression of DCTN2 protein CTD PMID:34122009 NCBI chr 7:63,092,061...63,107,560
Ensembl chr 7:63,092,057...63,108,543 		JBrowse link
G Ddx17 DEAD-box helicase 17 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DDX17 protein CTD PMID:34122009 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DDX3X protein CTD PMID:34122009 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Dgcr6 DiGeorge syndrome critical region gene 6 decreases expression ISO Benztropine results in decreased expression of DGCR6 protein CTD PMID:34122009 NCBI chr11:82,927,725...82,932,823
Ensembl chr11:82,927,725...82,932,823 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO Benztropine results in increased expression of DHCR24 protein CTD PMID:34122009 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G Dhx8 DEAH-box helicase 8 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DHX8 protein CTD PMID:34122009 NCBI chr10:86,667,641...86,704,198
Ensembl chr10:86,667,834...86,705,137 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase multiple interactions
increases expression		 ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DLAT protein
Benztropine results in increased expression of DLAT protein		 CTD PMID:34122009 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479 		JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression ISO Benztropine results in increased expression of DLG2 protein CTD PMID:34122009 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 increases expression ISO Benztropine results in increased expression of DNAJB11 protein CTD PMID:34122009 NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407 		JBrowse link
G Dpp3 dipeptidylpeptidase 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DPP3 protein CTD PMID:34122009 NCBI chr 1:202,204,683...202,228,501
Ensembl chr 1:202,204,693...202,228,541 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases expression ISO Benztropine results in decreased expression of DPYSL2 protein CTD PMID:34122009 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829 		JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of DPYSL3 protein CTD PMID:34122009 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157 		JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 decreases expression ISO Benztropine results in decreased expression of DYNC1LI1 protein CTD PMID:34122009 NCBI chr 8:114,376,649...114,410,297
Ensembl chr 8:114,376,662...114,410,934 		JBrowse link
G Ebna1bp2 EBNA1 binding protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EBNA1BP2 protein CTD PMID:34122009 NCBI chr 5:132,148,164...132,152,730
Ensembl chr 5:132,148,143...132,153,267 		JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EEF1G protein CTD PMID:34122009 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382 		JBrowse link
G Eif2s3 eukaryotic translation initiation factor 2 subunit gamma increases expression ISO Benztropine results in increased expression of EIF2S3 protein CTD PMID:34122009 NCBI chr  X:58,916,513...58,939,923
Ensembl chr  X:58,917,490...58,940,686 		JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF3B protein CTD PMID:34122009 NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886 		JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF3C protein CTD PMID:34122009 NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493 		JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H decreases expression ISO Benztropine results in decreased expression of EIF3H protein CTD PMID:34122009 NCBI chr 7:83,091,037...83,174,451
Ensembl chr 7:83,091,039...83,174,451 		JBrowse link
G Eif3l eukaryotic translation initiation factor 3, subunit L increases expression
multiple interactions		 ISO Benztropine results in increased expression of EIF3L protein
[Cuprizone co-treated with Benztropine] results in decreased expression of EIF3L protein		 CTD PMID:34122009 NCBI chr 7:110,652,565...110,663,614
Ensembl chr 7:110,627,107...110,663,614 		JBrowse link
G Eif5 eukaryotic translation initiation factor 5 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF5 protein CTD PMID:34122009 NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656 		JBrowse link
G Eif5b eukaryotic translation initiation factor 5B multiple interactions
increases expression		 ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF5B protein
Benztropine results in increased expression of EIF5B protein		 CTD PMID:34122009 NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482 		JBrowse link
G Eif6 eukaryotic translation initiation factor 6 decreases expression ISO Benztropine results in decreased expression of EIF6 protein CTD PMID:34122009 NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401 		JBrowse link
G Eno1 enolase 1 decreases expression ISO Benztropine results in decreased expression of ENO1 protein CTD PMID:34122009 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Ephb3 Eph receptor B3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EPHB3 protein CTD PMID:34122009 NCBI chr11:79,840,668...79,859,345
Ensembl chr11:79,840,668...79,859,370 		JBrowse link
G Epn1 Epsin 1 decreases expression ISO Benztropine results in decreased expression of EPN1 protein CTD PMID:34122009 NCBI chr 1:68,742,491...68,760,570
Ensembl chr 1:68,742,789...68,758,874 		JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor decreases expression ISO Benztropine results in decreased expression of EPS8 protein CTD PMID:34122009 NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873 		JBrowse link
G Erh ERH, mRNA splicing and mitosis factor increases expression ISO Benztropine results in increased expression of ERH protein CTD PMID:34122009 NCBI chr 6:100,280,933...100,291,200
Ensembl chr 6:100,280,930...100,291,210 		JBrowse link
G Erlin2 ER lipid raft associated 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of ERLIN2 protein CTD PMID:34122009 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671 		JBrowse link
G Ewsr1 EWS RNA-binding protein 1 decreases expression ISO Benztropine results in decreased expression of EWSR1 protein CTD PMID:34122009 NCBI chr14:79,965,365...79,994,108
Ensembl chr14:79,965,368...79,994,544 		JBrowse link
G Exosc9 exosome component 9 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EXOSC9 protein CTD PMID:34122009 NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051 		JBrowse link
G Ezr ezrin decreases expression ISO Benztropine results in decreased expression of EZR protein CTD PMID:34122009 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Fabp3 fatty acid binding protein 3 increases expression ISO Benztropine results in increased expression of FABP3 protein CTD PMID:34122009 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718 		JBrowse link
G Fdps farnesyl diphosphate synthase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of FDPS protein CTD PMID:34122009 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Flot2 flotillin 2 increases expression ISO Benztropine results in increased expression of FLOT2 protein CTD PMID:34122009 NCBI chr10:62,926,047...62,947,759
Ensembl chr10:62,920,665...62,947,756 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO Benztropine results in decreased expression of FLT1 protein CTD PMID:34122009 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fyco1 FYVE and coiled-coil domain autophagy adaptor 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of FYCO1 protein CTD PMID:34122009 NCBI chr 8:123,412,105...123,479,315
Ensembl chr 8:123,412,112...123,479,021 		JBrowse link
G G3bp2 G3BP stress granule assembly factor 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of G3BP2 protein CTD PMID:34122009 NCBI chr14:15,932,403...16,020,555
Ensembl chr14:15,987,417...16,020,548 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression ISO Benztropine results in decreased expression of G6PD protein CTD PMID:34122009 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GALNT2 protein CTD PMID:34122009 NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GART protein CTD PMID:34122009 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125 		JBrowse link
G Gatad2b GATA zinc finger domain containing 2B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GATAD2B protein CTD PMID:34122009 NCBI chr 2:175,748,594...175,829,837
Ensembl chr 2:175,749,433...175,825,542 		JBrowse link
G Gda guanine deaminase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GDA protein CTD PMID:34122009 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416 		JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 decreases expression ISO Benztropine results in decreased expression of GFPT1 protein CTD PMID:34122009 NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471 		JBrowse link
G Ggct gamma-glutamyl cyclotransferase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GGCT protein CTD PMID:34122009 NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277 		JBrowse link
G Glrx3 glutaredoxin 3 increases expression ISO Benztropine results in increased expression of GLRX3 protein CTD PMID:34122009 NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010 		JBrowse link
G Gls glutaminase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GLS protein CTD PMID:34122009 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900 		JBrowse link
G Gna12 G protein subunit alpha 12 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GNA12 protein CTD PMID:34122009 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255 		JBrowse link
G Golga4 golgin A4 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GOLGA4 protein CTD PMID:34122009 NCBI chr 8:118,208,200...118,285,003 JBrowse link
G Golgb1 golgin B1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GOLGB1 protein CTD PMID:34122009 NCBI chr11:63,843,179...63,900,665
Ensembl chr11:63,843,986...63,900,770 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GOT2 protein CTD PMID:34122009 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Gpi glucose-6-phosphate isomerase increases expression ISO Benztropine results in increased expression of GPI protein CTD PMID:34122009 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086 		JBrowse link
G Gpkow G patch domain and KOW motifs multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GPKOW protein CTD PMID:34122009 NCBI chr  X:14,791,601...14,806,384
Ensembl chr  X:14,791,610...14,806,384 		JBrowse link
G Gtf2e1 general transcription factor IIE subunit 1 decreases expression ISO Benztropine results in decreased expression of GTF2E1 protein CTD PMID:34122009 NCBI chr11:63,182,073...63,215,349
Ensembl chr11:63,182,349...63,213,942 		JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GTF2F1 protein CTD PMID:34122009 NCBI chr 9:1,844,027...1,853,455
Ensembl chr 9:1,843,901...1,853,423 		JBrowse link
G Gtpbp4 GTP binding protein 4 increases expression ISO Benztropine results in increased expression of GTPBP4 protein CTD PMID:34122009 NCBI chr17:61,308,033...61,328,184
Ensembl chr17:61,308,014...61,418,009 		JBrowse link
G Gys1 glycogen synthase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GYS1 protein CTD PMID:34122009 NCBI chr 1:95,915,443...95,935,292
Ensembl chr 1:95,915,443...95,935,292 		JBrowse link
G H2ac20 H2A clustered histone 20 increases expression ISO Benztropine results in increased expression of H2AC20 protein CTD PMID:34122009 NCBI chr 2:183,779,879...183,780,357 JBrowse link
G H2aj H2A.J histone increases expression ISO Benztropine results in increased expression of H2AJ protein CTD PMID:34122009 NCBI chr 4:169,675,718...169,676,202
Ensembl chr 4:169,675,752...169,677,006 		JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 increases expression ISO Benztropine results in increased expression of HACD3 protein CTD PMID:34122009 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression ISO Benztropine results in increased expression of HADHB protein CTD PMID:34122009 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869 		JBrowse link
G Hars1 histidyl-tRNA synthetase 1 increases expression ISO Benztropine results in increased expression of HARS1 protein CTD PMID:34122009 NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740 		JBrowse link
G Hat1 histone acetyltransferase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of HAT1 protein CTD PMID:34122009 NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517 		JBrowse link
G Hcfc1 host cell factor C1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HCFC1 protein CTD PMID:34122009 NCBI chr  X:151,687,779...151,712,688
Ensembl chr  X:151,687,779...151,712,638 		JBrowse link
G Hmcn2 hemicentin 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HMCN2 protein CTD PMID:34122009 NCBI chr 3:14,588,353...14,738,320
Ensembl chr 3:14,588,662...14,738,025 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D decreases expression ISO Benztropine results in decreased expression of HNRNPD protein CTD PMID:34122009 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of HNRNPK protein CTD PMID:34122009 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997 		JBrowse link
G Hps3 HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HPS3 protein CTD PMID:34122009 NCBI chr 2:102,484,574...102,527,580
Ensembl chr 2:102,484,574...102,526,047 		JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 increases expression ISO Benztropine results in increased expression of HSD17B12 protein CTD PMID:34122009 NCBI chr 3:79,990,048...80,113,556
Ensembl chr 3:79,990,056...80,113,617 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of HSD17B4 protein CTD PMID:34122009 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HSP90B1 protein CTD PMID:34122009 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Benztropine results in decreased expression of IDI1 protein CTD PMID:34122009 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Benztropine results in decreased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Benztropine results in decreased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il24 interleukin 24 increases expression ISO Benztropine results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Jam3 junctional adhesion molecule 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of JAM3 protein CTD PMID:34122009 NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355 		JBrowse link
G Jpt2 Jupiter microtubule associated homolog 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of JPT2 protein CTD PMID:34122009 NCBI chr10:13,963,135...13,983,212
Ensembl chr10:13,963,137...13,983,170 		JBrowse link
G Kars1 lysyl-tRNA synthetase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of KARS1 protein CTD PMID:34122009 NCBI chr19:39,957,846...39,976,837
Ensembl chr19:39,957,846...39,977,632 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Benztropine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 decreases expression ISO Benztropine results in decreased expression of KCTD12 protein CTD PMID:34122009 NCBI chr15:79,800,078...79,806,017
Ensembl chr15:79,801,191...79,806,282 		JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 decreases expression ISO Benztropine results in decreased expression of KHDRBS1 protein CTD PMID:34122009 NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180 		JBrowse link
G Kif5c kinesin family member 5C decreases expression ISO Benztropine results in decreased expression of KIF5C protein CTD PMID:34122009 NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413 		JBrowse link
G Klhdc2 kelch domain containing 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of KLHDC2 protein CTD PMID:34122009 NCBI chr 6:87,777,183...87,791,609
Ensembl chr 6:87,777,183...87,804,187 		JBrowse link
G Klhl41 kelch-like family member 41 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of KLHL41 protein CTD PMID:34122009 NCBI chr 3:54,434,291...54,447,415
Ensembl chr 3:54,434,234...54,449,222 		JBrowse link
G Kpna4 karyopherin subunit alpha 4 increases expression ISO Benztropine results in increased expression of KPNA4 protein CTD PMID:34122009 NCBI chr 2:153,319,380...153,381,085
Ensembl chr 2:153,324,273...153,381,081 		JBrowse link
G Ktn1 kinectin 1 multiple interactions
decreases expression		 ISO [Cuprizone co-treated with Benztropine] results in increased expression of KTN1 protein
Benztropine results in decreased expression of KTN1 protein		 CTD PMID:34122009 NCBI chr15:20,913,665...21,002,588
Ensembl chr15:20,914,642...21,002,578 		JBrowse link
G Lactb2 lactamase, beta 2 increases expression ISO Benztropine results in increased expression of LACTB2 protein CTD PMID:34122009 NCBI chr 5:5,569,080...5,591,843
Ensembl chr 5:5,569,067...5,596,429 		JBrowse link
G Lamb1 laminin subunit beta 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of LAMB1 protein CTD PMID:34122009 NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585 		JBrowse link
G Lamc1 laminin subunit gamma 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of LAMC1 protein CTD PMID:34122009 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492 		JBrowse link
G Lima1 LIM domain and actin binding 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of LIMA1 protein CTD PMID:34122009 NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473 		JBrowse link
G Lipa lipase A, lysosomal acid type increases expression ISO Benztropine results in increased expression of LIPA protein CTD PMID:34122009 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Lmod2 leiomodin 2 increases expression ISO Benztropine results in increased expression of LMOD2 protein CTD PMID:34122009 NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120 		JBrowse link
G Lss lanosterol synthase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of LSS protein CTD PMID:34122009 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Lta4h leukotriene A4 hydrolase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of LTA4H protein CTD PMID:34122009 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600 		JBrowse link
G Luc7l LUC7-like multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of LUC7L protein CTD PMID:34122009 NCBI chr10:15,273,340...15,307,131
Ensembl chr10:15,273,348...15,303,112 		JBrowse link
G Magea9 MAGE family member A9 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MAGEA9 protein CTD PMID:34122009 NCBI chr  X:142,619,282...142,624,654
Ensembl chr  X:142,619,395...142,624,653 		JBrowse link
G Maged2 MAGE family member D2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MAGED2 protein CTD PMID:34122009 NCBI chr  X:19,733,593...19,741,769
Ensembl chr  X:19,733,597...19,740,477 		JBrowse link
G Map1s microtubule-associated protein 1S increases expression ISO Benztropine results in increased expression of MAP1S protein CTD PMID:34122009 NCBI chr16:18,516,759...18,527,777
Ensembl chr16:18,517,574...18,527,988 		JBrowse link
G Map4 microtubule-associated protein 4 decreases expression ISO Benztropine results in decreased expression of MAP4 protein CTD PMID:34122009 NCBI chr 8:109,925,233...110,064,370
Ensembl chr 8:109,925,575...110,064,362 		JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 decreases expression ISO Benztropine results in decreased expression of MAPRE1 protein CTD PMID:34122009 NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983 		JBrowse link
G Marcksl1 MARCKS-like 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MARCKSL1 protein CTD PMID:34122009 NCBI chr 5:141,851,491...141,853,814
Ensembl chr 5:141,850,110...141,853,817 		JBrowse link
G Mat2b methionine adenosyltransferase 2 non-catalytic beta subunit multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of MAT2B protein CTD PMID:34122009 NCBI chr10:25,106,928...25,122,982
Ensembl chr10:25,106,930...25,122,777 		JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 decreases expression ISO Benztropine results in decreased expression of MBOAT7 protein CTD PMID:34122009 NCBI chr 1:65,525,206...65,539,538
Ensembl chr 1:65,525,213...65,539,538 		JBrowse link
G Mdh1 malate dehydrogenase 1 decreases expression ISO Benztropine results in decreased expression of MDH1 protein CTD PMID:34122009 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO Benztropine results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Metap2 methionyl aminopeptidase 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of METAP2 protein CTD PMID:34122009 NCBI chr 7:28,412,429...28,440,458
Ensembl chr 7:28,411,608...28,440,434 		JBrowse link
G Mif macrophage migration inhibitory factor increases expression ISO Benztropine results in increased expression of MIF protein CTD PMID:34122009 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Mtdh metadherin multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MTDH protein CTD PMID:34122009 NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413 		JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of MTHFD1L protein CTD PMID:34122009 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905 		JBrowse link
G Myh3 myosin heavy chain 3 increases expression ISO Benztropine results in increased expression of MYH3 protein CTD PMID:34122009 NCBI chr10:51,770,177...51,793,994
Ensembl chr10:51,770,177...51,793,992 		JBrowse link
G Nat10 N-acetyltransferase 10 decreases expression ISO Benztropine results in decreased expression of NAT10 protein CTD PMID:34122009 NCBI chr 3:90,111,643...90,149,891
Ensembl chr 3:90,111,645...90,149,927 		JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 decreases expression ISO Benztropine results in decreased expression of NCBP1 protein CTD PMID:34122009 NCBI chr 5:60,416,023...60,449,004
Ensembl chr 5:60,415,982...60,449,089 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 decreases expression ISO Benztropine results in decreased expression of NECTIN2 protein CTD PMID:34122009 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Nnmt nicotinamide N-methyltransferase increases expression ISO Benztropine results in increased expression of NNMT protein CTD PMID:34122009 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655 		JBrowse link
G Noc2l NOC2-like nucleolar associated transcriptional repressor increases expression ISO Benztropine results in increased expression of NOC2L protein CTD PMID:34122009 NCBI chr 5:166,820,150...166,831,949
Ensembl chr 5:166,820,161...166,831,949 		JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression ISO Benztropine results in decreased expression of NSF protein CTD PMID:34122009 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386 		JBrowse link
G Nsfl1c NSFL1 cofactor decreases expression ISO Benztropine results in decreased expression of NSFL1C protein CTD PMID:34122009 NCBI chr 3:139,978,306...140,002,876
Ensembl chr 3:139,978,301...140,002,870 		JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of NUMA1 protein CTD PMID:34122009 NCBI chr 1:156,297,907...156,372,855
Ensembl chr 1:156,326,259...156,372,855 		JBrowse link
G Nup153 nucleoporin 153 increases expression ISO Benztropine results in increased expression of NUP153 protein CTD PMID:34122009 NCBI chr17:17,972,217...18,024,876
Ensembl chr17:17,972,217...18,024,876 		JBrowse link
G Nup50 nucleoporin 50 increases expression ISO Benztropine results in increased expression of NUP50 protein CTD PMID:34122009 NCBI chr 7:116,047,960...116,065,231
Ensembl chr 7:116,048,021...116,066,905 		JBrowse link
G Nup54 nucleoporin 54 decreases expression ISO Benztropine results in decreased expression of NUP54 protein CTD PMID:34122009 NCBI chr14:15,617,630...15,636,029
Ensembl chr14:15,617,679...15,636,028 		JBrowse link
G Nup93 nucleoporin 93 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of NUP93 protein CTD PMID:34122009 NCBI chr19:10,684,214...10,788,009
Ensembl chr19:10,682,075...10,788,026 		JBrowse link
G Nxf1 nuclear RNA export factor 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of NXF1 protein CTD PMID:34122009 NCBI chr 1:205,655,442...205,668,637
Ensembl chr 1:205,655,375...205,668,636 		JBrowse link
G Oat ornithine aminotransferase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of OAT protein CTD PMID:34122009 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682 		JBrowse link
G Ogdh oxoglutarate dehydrogenase decreases expression ISO Benztropine results in decreased expression of OGDH protein CTD PMID:34122009 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479 		JBrowse link
G Ola1 Obg-like ATPase 1 increases expression ISO Benztropine results in increased expression of OLA1 protein CTD PMID:34122009 NCBI chr 3:57,966,896...58,085,955
Ensembl chr 3:57,966,896...58,084,480 		JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta decreases expression ISO Benztropine results in decreased expression of P4HB protein CTD PMID:34122009 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500 		JBrowse link
G Pa2g4 proliferation-associated 2G4 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PA2G4 protein CTD PMID:34122009 NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PAFAH1B1 protein CTD PMID:34122009 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 decreases expression ISO Benztropine results in decreased expression of PAG1 protein CTD PMID:34122009 NCBI chr 2:91,935,378...92,076,937
Ensembl chr 2:92,057,216...92,069,849 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
decreases expression		 ISO [Cuprizone co-treated with Benztropine] results in increased expression of PARP1 protein
Benztropine results in decreased expression of PARP1 protein		 CTD PMID:34122009 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pc pyruvate carboxylase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of PC protein CTD PMID:34122009 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380 		JBrowse link
G Pcbp1 poly(rC) binding protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PCBP1 protein CTD PMID:34122009 NCBI chr 4:118,972,698...118,974,705
Ensembl chr 4:118,972,661...118,976,500 		JBrowse link
G Pcbp2 poly(rC) binding protein 2 decreases expression ISO Benztropine results in decreased expression of PCBP2 protein CTD PMID:34122009 NCBI chr 7:133,605,375...133,631,312
Ensembl chr 7:133,605,573...133,629,863 		JBrowse link
G Pcdhga2 protocadherin gamma subfamily A, 2 decreases expression ISO Benztropine results in decreased expression of PCDHGA2 protein CTD PMID:34122009 NCBI chr18:29,493,954...29,667,865
Ensembl chr18:29,493,954...29,667,868 		JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 decreases expression ISO Benztropine results in decreased expression of PCMT1 protein CTD PMID:34122009 NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201 		JBrowse link
G Pcnp PEST proteolytic signal containing nuclear protein increases expression ISO Benztropine results in increased expression of PCNP protein CTD PMID:34122009 NCBI chr11:44,592,766...44,607,372
Ensembl chr11:44,592,742...44,607,348 		JBrowse link
G Pdcl3 phosducin-like 3 decreases expression ISO Benztropine results in decreased expression of PDCL3 protein CTD PMID:34122009 NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 decreases expression ISO Benztropine results in decreased expression of PDIA3 protein CTD PMID:34122009 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PDIA6 protein CTD PMID:34122009 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 decreases expression ISO Benztropine results in decreased expression of PDLIM5 protein CTD PMID:34122009 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275 		JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 decreases expression ISO Benztropine results in decreased expression of PEBP1 protein CTD PMID:34122009 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862 		JBrowse link
G Pfn1 profilin 1 increases expression ISO Benztropine results in increased expression of PFN1 protein CTD PMID:34122009 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 decreases expression ISO Benztropine results in decreased expression of PGK1 protein CTD PMID:34122009 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Pgm3 phosphoglucomutase 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PGM3 protein CTD PMID:34122009 NCBI chr 8:87,518,317...87,536,021
Ensembl chr 8:87,517,701...87,536,022 		JBrowse link
G Phf14 PHD finger protein 14 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PHF14 protein CTD PMID:34122009 NCBI chr 4:40,009,691...40,195,877
Ensembl chr 4:40,009,264...40,195,885 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression ISO Benztropine results in decreased expression of PHGDH protein CTD PMID:34122009 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Benztropine results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PIN1 protein CTD PMID:34122009 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785 		JBrowse link
G Pmpca peptidase, mitochondrial processing subunit alpha increases expression ISO Benztropine results in increased expression of PMPCA protein CTD PMID:34122009 NCBI chr 3:9,207,731...9,216,846
Ensembl chr 3:9,207,717...9,216,844 		JBrowse link
G Pnma1 PNMA family member 1 increases expression ISO Benztropine results in increased expression of PNMA1 protein CTD PMID:34122009 NCBI chr 6:103,782,244...103,784,029
Ensembl chr 6:103,773,889...103,784,567 		JBrowse link
G Pnma8a PNMA family member 8A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PNMA8A protein CTD PMID:34122009 NCBI chr 1:77,629,272...77,643,156
Ensembl chr 1:77,639,423...77,642,082 		JBrowse link
G Pon3 paraoxonase 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PON3 protein CTD PMID:34122009 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855 		JBrowse link
G Ppa1 inorganic pyrophosphatase 1 multiple interactions
increases expression		 ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PPA1 protein
Benztropine results in increased expression of PPA1 protein		 CTD PMID:34122009 NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215 		JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F decreases expression ISO Benztropine results in decreased expression of PPM1F protein CTD PMID:34122009 NCBI chr11:84,064,422...84,094,410
Ensembl chr11:84,064,420...84,094,340 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of PPP1R12A protein CTD PMID:34122009 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425 		JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PPP1R14B protein CTD PMID:34122009 NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha increases expression ISO Benztropine results in increased expression of PPP3CA protein CTD PMID:34122009 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PRKAR2A protein CTD PMID:34122009 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628 		JBrowse link
G Prkcsh PRKCSH beta subunit of glucosidase II multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of PRKCSH protein CTD PMID:34122009 NCBI chr 8:20,534,787...20,546,493
Ensembl chr 8:20,534,880...20,546,492 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 decreases expression ISO Benztropine results in decreased expression of PRMT1 protein CTD PMID:34122009 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345 		JBrowse link
G Prpf6 pre-mRNA processing factor 6 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PRPF6 protein CTD PMID:34122009 NCBI chr 3:168,706,952...168,771,191
Ensembl chr 3:168,704,299...168,774,991 		JBrowse link
G Psma1 proteasome 20S subunit alpha 1 decreases expression ISO Benztropine results in decreased expression of PSMA1 protein CTD PMID:34122009 NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472 		JBrowse link
G Psmb7 proteasome 20S subunit beta 7 decreases expression ISO Benztropine results in decreased expression of PSMB7 protein CTD PMID:34122009 NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937 		JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 decreases expression ISO Benztropine results in decreased expression of PSMC1 protein CTD PMID:34122009 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123 		JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 increases expression ISO Benztropine results in increased expression of PSMC3 protein CTD PMID:34122009 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358 		JBrowse link
G Psmd7 proteasome 26S subunit, non-ATPase 7 increases expression ISO Benztropine results in increased expression of PSMD7 protein CTD PMID:34122009 NCBI chr19:35,494,317...35,501,605
Ensembl chr19:35,494,316...35,501,588 		JBrowse link
G Ptcd3 Pentatricopeptide repeat domain 3 increases expression
multiple interactions		 ISO Benztropine results in increased expression of PTCD3 protein
[Cuprizone co-treated with Benztropine] results in decreased expression of PTCD3 protein		 CTD PMID:34122009 NCBI chr 4:103,922,440...103,957,445
Ensembl chr 4:103,920,566...103,957,538 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Benztropine results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk7 protein tyrosine kinase 7 decreases expression ISO Benztropine results in decreased expression of PTK7 protein CTD PMID:34122009 NCBI chr 9:14,352,155...14,418,473
Ensembl chr 9:14,351,202...14,418,494 		JBrowse link
G Puf60 poly-U binding splicing factor 60 decreases expression ISO Benztropine results in decreased expression of PUF60 protein CTD PMID:34122009 NCBI chr 7:107,782,799...107,793,759
Ensembl chr 7:107,782,770...107,794,531 		JBrowse link
G Pwp2 PWP2, small subunit processome component increases expression ISO Benztropine results in increased expression of PWP2 protein CTD PMID:34122009 NCBI chr20:10,499,332...10,512,965
Ensembl chr20:10,499,363...10,513,640 		JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 increases expression ISO Benztropine results in increased expression of PYCR1 protein CTD PMID:34122009 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549 		JBrowse link
G Qdpr quinoid dihydropteridine reductase decreases expression ISO Benztropine results in decreased expression of QDPR protein CTD PMID:34122009 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854 		JBrowse link
G Rack1 receptor for activated C kinase 1 decreases expression ISO Benztropine results in decreased expression of RACK1 protein CTD PMID:34122009 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Rbm15 RNA binding motif protein 15 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of RBM15 protein CTD PMID:34122009 NCBI chr 2:194,945,974...194,954,498
Ensembl chr 2:194,945,974...194,954,703 		JBrowse link
G Ric8a RIC8 guanine nucleotide exchange factor A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of RIC8A protein CTD PMID:34122009 NCBI chr 1:195,935,162...195,941,469
Ensembl chr 1:195,935,349...195,941,467 		JBrowse link
G Rpl10a ribosomal protein L10A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPL10A protein CTD PMID:34122009 NCBI chr20:6,388,800...6,391,358
Ensembl chr20:6,385,823...6,391,357 		JBrowse link
G Rpl19 ribosomal protein L19 increases expression ISO Benztropine results in increased expression of RPL19 protein CTD PMID:34122009 NCBI chr10:83,022,503...83,026,030
Ensembl chr10:83,019,257...83,052,112 		JBrowse link
G Rpl24 ribosomal protein L24 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPL24 protein CTD PMID:34122009 NCBI chr11:44,653,937...44,659,346
Ensembl chr11:44,653,937...44,659,370 		JBrowse link
G Rpl30 ribosomal protein L30 increases expression ISO Benztropine results in increased expression of RPL30 protein CTD PMID:34122009 NCBI chr 7:65,648,266...65,651,401
Ensembl chr 7:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363 		JBrowse link
G Rpl7a ribosomal protein L7A decreases expression ISO Benztropine results in decreased expression of RPL7A protein CTD PMID:34122009 NCBI chr 3:10,239,026...10,241,703
Ensembl chr 3:10,239,001...10,241,716 		JBrowse link
G Rplp1 ribosomal protein lateral stalk subunit P1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPLP1 protein CTD PMID:34122009 NCBI chr 8:62,394,008...62,395,341
Ensembl chr 8:62,393,177...62,395,339 		JBrowse link
G Rps12 ribosomal protein S12 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPS12 protein CTD PMID:34122009 NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014 		JBrowse link
G Rps18 ribosomal protein S18 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPS18 protein CTD PMID:34122009 NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146
Ensembl chr20:101,204,500...101,205,146 		JBrowse link
G Rps27 ribosomal protein S27 increases expression ISO Benztropine results in increased expression of RPS27 protein CTD PMID:34122009 NCBI chr 2:175,665,858...175,666,963
Ensembl chr 2:175,665,853...175,666,964 		JBrowse link
G Rps27a ribosomal protein S27a increases expression ISO Benztropine results in increased expression of RPS27A protein CTD PMID:34122009 NCBI chr14:103,285,734...103,288,011
Ensembl chr14:103,285,734...103,288,011
Ensembl chr 5:103,285,734...103,288,011 		JBrowse link
G Rps3 ribosomal protein S3 decreases expression ISO Benztropine results in decreased expression of RPS3 protein CTD PMID:34122009 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 increases expression ISO Benztropine results in increased expression of RUVBL2 protein CTD PMID:34122009 NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342 		JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SAE1 protein CTD PMID:34122009 NCBI chr 1:77,030,961...77,086,937
Ensembl chr 1:77,030,965...77,086,986 		JBrowse link
G Sars1 seryl-tRNA synthetase 1 decreases expression ISO Benztropine results in decreased expression of SARS1 protein CTD PMID:34122009 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277 		JBrowse link
G Satb2 SATB homeobox 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SATB2 protein CTD PMID:34122009 NCBI chr 9:58,348,027...58,534,256
Ensembl chr 9:58,350,246...58,530,707 		JBrowse link
G Sccpdh saccharopine dehydrogenase (putative) decreases expression ISO Benztropine results in decreased expression of SCCPDH protein CTD PMID:34122009 NCBI chr13:91,400,120...91,421,875
Ensembl chr13:91,400,190...91,422,222 		JBrowse link
G Sdcbp syndecan binding protein decreases expression ISO Benztropine results in decreased expression of SDCBP protein CTD PMID:34122009 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572 		JBrowse link
G Sec23a Sec23 homolog A, COPII coat complex component multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SEC23A protein CTD PMID:34122009 NCBI chr 6:76,658,793...76,706,125
Ensembl chr 6:76,658,427...76,706,035 		JBrowse link
G Sec61b SEC61 translocon subunit beta increases expression ISO Benztropine results in increased expression of SEC61B protein CTD PMID:34122009 NCBI chr 5:61,773,594...61,781,804
Ensembl chr 5:61,773,594...61,781,804 		JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator increases expression ISO Benztropine results in increased expression of SEC63 protein CTD PMID:34122009 NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055 		JBrowse link
G Serbp1 Serpine1 mRNA binding protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SERBP1 protein CTD PMID:34122009 NCBI chr 4:96,401,587...96,421,816
Ensembl chr 4:96,401,477...96,421,813 		JBrowse link
G Serpinb3a serpin family B member 3A increases expression ISO Benztropine results in increased expression of SERPINB4 protein CTD PMID:34122009 NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985 		JBrowse link
G Sf1 splicing factor 1 decreases expression ISO Benztropine results in decreased expression of SF1 protein CTD PMID:34122009 NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330 		JBrowse link
G Sf3b3 splicing factor 3b, subunit 3 decreases expression ISO Benztropine results in decreased expression of SF3B3 protein CTD PMID:34122009 NCBI chr19:38,782,749...38,820,271
Ensembl chr19:38,783,040...38,820,245 		JBrowse link
G Sgca sarcoglycan, alpha decreases expression ISO Benztropine results in decreased expression of SGCA protein CTD PMID:34122009 NCBI chr10:79,904,698...79,922,808
Ensembl chr10:79,908,738...79,922,813 		JBrowse link
G Sh3pxd2b SH3 and PX domains 2B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SH3PXD2B protein CTD PMID:34122009 NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SHMT1 protein CTD PMID:34122009 NCBI chr10:45,468,698...45,490,833
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Benztropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc25a5-ps11 solute carrier family 25 member 5, pseudogene 11 increases expression ISO Benztropine results in increased expression of SLC25A6 protein CTD PMID:34122009 NCBI chr18:68,571,222...68,572,461
Ensembl chr18:68,571,300...68,572,199 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression ISO Benztropine results in decreased expression of SLC2A1 protein CTD PMID:34122009 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc38a2 solute carrier family 38, member 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SLC38A2 protein CTD PMID:34122009 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SLC3A2 protein CTD PMID:34122009 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO Benztropine inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:17250655 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Benztropine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 decreases expression ISO Benztropine results in decreased expression of SMARCB1 protein CTD PMID:34122009 NCBI chr20:12,741,164...12,763,616
Ensembl chr20:12,741,477...12,763,620 		JBrowse link
G Smc3 structural maintenance of chromosomes 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SMC3 protein CTD PMID:34122009 NCBI chr 1:252,601,422...252,644,522
Ensembl chr 1:252,601,753...252,644,522 		JBrowse link
G Smu1 SMU1, DNA replication regulator and spliceosomal factor multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SMU1 protein CTD PMID:34122009 NCBI chr 5:55,856,691...55,875,262
Ensembl chr 5:55,856,246...55,875,300 		JBrowse link
G Snrnp200 small nuclear ribonucleoprotein U5 subunit 200 multiple interactions
increases expression		 ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SNRNP200 protein
Benztropine results in increased expression of SNRNP200 protein		 CTD PMID:34122009 NCBI chr 3:114,428,854...114,458,194
Ensembl chr 3:114,428,854...114,458,182 		JBrowse link
G Snrpa small nuclear ribonucleoprotein polypeptide A increases expression ISO Benztropine results in increased expression of SNRPA protein CTD PMID:34122009 NCBI chr 1:82,481,770...82,490,540
Ensembl chr 1:82,481,770...82,490,538 		JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide increases expression ISO Benztropine results in increased expression of SNRPD2 protein CTD PMID:34122009 NCBI chr 1:78,798,377...78,801,227
Ensembl chr 1:78,798,377...78,803,351 		JBrowse link
G Srek1 splicing regulatory glutamic acid and lysine rich protein 1 decreases expression ISO Benztropine results in decreased expression of SREK1 protein CTD PMID:34122009 NCBI chr 2:34,849,548...34,885,120
Ensembl chr 2:34,852,458...34,884,972 		JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 increases expression ISO Benztropine results in increased expression of SRSF5 protein CTD PMID:34122009 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of STAT3 protein CTD PMID:34122009 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stim1 stromal interaction molecule 1 decreases expression ISO Benztropine results in decreased expression of STIM1 protein CTD PMID:34122009 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO Benztropine results in decreased expression of STIP1 protein CTD PMID:34122009 NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476 		JBrowse link
G Strap serine/threonine kinase receptor associated protein decreases expression ISO Benztropine results in decreased expression of STRAP protein CTD PMID:34122009 NCBI chr 4:170,646,042...170,660,291
Ensembl chr 4:170,646,001...170,660,828 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of STUB1 protein CTD PMID:34122009 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha decreases expression ISO Benztropine results in decreased expression of SUCLG1 protein CTD PMID:34122009 NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:105,308,039...105,337,600 		JBrowse link
G Sumo2 small ubiquitin-like modifier 2 decreases expression ISO Benztropine results in decreased expression of SUMO2 protein CTD PMID:34122009 NCBI chr10:100,771,941...100,784,503
Ensembl chr10:100,686,797...100,784,513 		JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SUN1 protein CTD PMID:34122009 NCBI chr12:15,396,378...15,441,277
Ensembl chr12:15,396,381...15,441,571 		JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein decreases expression ISO Benztropine results in decreased expression of SYNCRIP protein CTD PMID:34122009 NCBI chr 8:89,402,487...89,435,517
Ensembl chr 8:89,402,866...89,435,515 		JBrowse link
G Tagln2 transgelin 2 decreases expression ISO Benztropine results in decreased expression of TAGLN2 protein CTD PMID:34122009 NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972 		JBrowse link
G Tbcb tubulin folding cofactor B decreases expression ISO Benztropine results in decreased expression of TBCB protein CTD PMID:34122009 NCBI chr 1:85,477,639...85,483,488
Ensembl chr 1:85,477,640...85,483,488 		JBrowse link
G Tcaf1 TRPM8 channel-associated factor 1 multiple interactions
decreases expression		 ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TCAF1 protein
Benztropine results in decreased expression of TCAF1 protein		 CTD PMID:34122009 NCBI chr 4:71,589,674...71,639,274
Ensembl chr 4:71,591,200...71,613,309 		JBrowse link
G Tgoln2 trans-golgi network protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TGOLN2 protein CTD PMID:34122009 NCBI chr 4:104,663,356...104,671,208
Ensembl chr 4:104,663,353...104,671,164 		JBrowse link
G Tln2 talin 2 decreases expression ISO Benztropine results in decreased expression of TLN2 protein CTD PMID:34122009 NCBI chr 8:67,830,920...68,252,240
Ensembl chr 8:67,834,326...68,252,219 		JBrowse link
G Tmpo thymopoietin decreases expression ISO Benztropine results in decreased expression of TMPO protein CTD PMID:34122009 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727 		JBrowse link
G Tnks1bp1 tankyrase 1 binding protein 1 multiple interactions
decreases expression		 ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TNKS1BP1 protein
Benztropine results in decreased expression of TNKS1BP1 protein		 CTD PMID:34122009 NCBI chr 3:70,135,335...70,160,071
Ensembl chr 3:70,137,837...70,160,038 		JBrowse link
G Tomm34 translocase of outer mitochondrial membrane 34 decreases expression
multiple interactions		 ISO Benztropine results in decreased expression of TOMM34 protein
[Cuprizone co-treated with Benztropine] results in increased expression of TOMM34 protein		 CTD PMID:34122009 NCBI chr 3:152,729,345...152,746,295
Ensembl chr 3:152,729,349...152,746,373 		JBrowse link
G Top1mt DNA topoisomerase I mitochondrial increases expression ISO Benztropine results in increased expression of TOP1MT protein CTD PMID:34122009 NCBI chr 7:107,338,092...107,368,125
Ensembl chr 7:107,342,527...107,366,049 		JBrowse link
G Tpm2 tropomyosin 2 decreases expression ISO Benztropine results in decreased expression of TPM2 protein CTD PMID:34122009 NCBI chr 5:57,770,919...57,780,278
Ensembl chr 5:57,770,864...57,779,992 		JBrowse link
G Tpm3 tropomyosin 3 decreases expression ISO Benztropine results in decreased expression of TPM3 protein CTD PMID:34122009 NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein decreases expression ISO Benztropine results in decreased expression of TPR protein CTD PMID:34122009 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496 		JBrowse link
G Trim28 tripartite motif-containing 28 decreases expression
multiple interactions		 ISO Benztropine results in decreased expression of TRIM28 protein
[Cuprizone co-treated with Benztropine] results in increased expression of TRIM28 protein		 CTD PMID:34122009 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380 		JBrowse link
G Tspan3 tetraspanin 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of TSPAN3 protein CTD PMID:34122009 NCBI chr 8:56,546,067...56,569,815
Ensembl chr 8:56,546,069...56,569,880 		JBrowse link
G Ttc21a tetratricopeptide repeat domain 21A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of TTC21A protein CTD PMID:34122009 NCBI chr 8:119,667,044...119,702,028
Ensembl chr 8:119,666,933...119,702,456 		JBrowse link
G Ttyh2 tweety family member 2 increases expression ISO Benztropine results in increased expression of TTYH2 protein CTD PMID:34122009 NCBI chr10:99,709,063...99,753,449
Ensembl chr10:99,709,007...99,753,444 		JBrowse link
G Ttyh3 tweety family member 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TTYH3 protein CTD PMID:34122009 NCBI chr12:13,996,831...14,025,457
Ensembl chr12:13,997,045...14,025,459 		JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression ISO Benztropine results in increased expression of TUBB protein CTD PMID:34122009 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940 		JBrowse link
G Twf2 twinfilin actin-binding protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TWF2 protein CTD PMID:34122009 NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298 		JBrowse link
G Txlna taxilin alpha decreases expression ISO Benztropine results in decreased expression of TXLNA protein CTD PMID:34122009 NCBI chr 5:141,969,337...141,985,054
Ensembl chr 5:141,969,346...141,984,583 		JBrowse link
G Tyms thymidylate synthetase increases expression ISO Benztropine results in increased expression of TYMS protein CTD PMID:34122009 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G U2af2 U2 small nuclear RNA auxiliary factor 2 decreases expression ISO Benztropine results in decreased expression of U2AF2 protein CTD PMID:34122009 NCBI chr 1:68,760,911...68,779,730
Ensembl chr 1:68,760,924...68,778,492 		JBrowse link
G Uba2 ubiquitin-like modifier activating enzyme 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of UBA2 protein CTD PMID:34122009 NCBI chr 1:86,775,239...86,802,685
Ensembl chr 1:86,775,244...86,802,682 		JBrowse link
G Ubap2l ubiquitin associated protein 2-like decreases expression ISO Benztropine results in decreased expression of UBAP2L protein CTD PMID:34122009 NCBI chr 2:175,438,703...175,494,085
Ensembl chr 2:175,438,703...175,493,998 		JBrowse link
G Ubc ubiquitin C increases expression ISO Benztropine results in increased expression of UBC protein CTD PMID:34122009 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925 		JBrowse link
G Ubqln2 ubiquilin 2 decreases expression ISO Benztropine results in decreased expression of UBQLN2 protein CTD PMID:34122009 NCBI chr  X:17,853,086...17,856,505
Ensembl chr  X:17,853,114...17,856,505 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of UCHL1 protein CTD PMID:34122009 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
G Uchl3 ubiquitin C-terminal hydrolase L3 decreases expression ISO Benztropine results in decreased expression of UCHL3 protein CTD PMID:34122009 NCBI chr15:78,485,304...78,527,355
Ensembl chr15:78,485,315...78,527,355
Ensembl chr 3:78,485,315...78,527,355 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase decreases expression ISO Benztropine results in decreased expression of UGDH protein CTD PMID:34122009 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354 		JBrowse link
G Unc45b unc-45 myosin chaperone B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of UNC45B protein CTD PMID:34122009 NCBI chr10:67,845,464...67,873,143
Ensembl chr10:67,845,462...67,873,389 		JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of UQCRC2 protein CTD PMID:34122009 NCBI chr 1:175,167,933...175,198,499
Ensembl chr 1:175,167,894...175,199,453 		JBrowse link
G Uso1 USO1 vesicle transport factor decreases expression ISO Benztropine results in decreased expression of USO1 protein CTD PMID:34122009 NCBI chr14:15,866,638...15,932,185
Ensembl chr14:15,866,638...15,932,171 		JBrowse link
G Usp10 ubiquitin specific peptidase 10 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of USP10 protein CTD PMID:34122009 NCBI chr19:47,972,858...48,014,900
Ensembl chr19:47,972,611...48,014,897 		JBrowse link
G Usp14 ubiquitin specific peptidase 14 increases expression ISO Benztropine results in increased expression of USP14 protein CTD PMID:34122009 NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519 		JBrowse link
G Utp18 UTP18 small subunit processome component increases expression ISO Benztropine results in increased expression of UTP18 protein CTD PMID:34122009 NCBI chr10:78,811,879...78,839,338
Ensembl chr10:78,811,880...78,839,627 		JBrowse link
G Vasp vasodilator-stimulated phosphoprotein decreases expression ISO Benztropine results in decreased expression of VASP protein CTD PMID:34122009 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061 		JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of WARS1 protein CTD PMID:34122009 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269 		JBrowse link
G Wdr12 WD repeat domain 12 decreases expression ISO Benztropine results in decreased expression of WDR12 protein CTD PMID:34122009 NCBI chr 9:61,475,498...61,502,762
Ensembl chr 9:61,475,517...61,502,469 		JBrowse link
G Xirp2 xin actin-binding repeat containing 2 decreases expression ISO Benztropine results in decreased expression of XIRP2 protein CTD PMID:34122009 NCBI chr 3:52,126,213...52,213,094
Ensembl chr 3:51,870,092...52,213,091 		JBrowse link
G Xpo7 exportin 7 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of XPO7 protein CTD PMID:34122009 NCBI chr15:45,742,053...45,828,050
Ensembl chr15:45,742,053...45,828,050 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta increases expression ISO Benztropine results in increased expression of YWHAQ protein CTD PMID:34122009 NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273 		JBrowse link
G Zbtb42 zinc finger and BTB domain containing 42 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of ZBTB42 protein CTD PMID:34122009 NCBI chr 6:131,734,257...131,742,459
Ensembl chr 6:131,738,356...131,742,685 		JBrowse link
G Zfr zinc finger RNA binding protein decreases expression ISO Benztropine results in decreased expression of ZFR protein CTD PMID:34122009 NCBI chr 2:61,137,611...61,200,322
Ensembl chr 2:61,137,611...61,200,322 		JBrowse link
G Zkscan7 zinc finger with KRAB and SCAN domains 7 decreases expression ISO Benztropine results in decreased expression of ZKSCAN7 protein CTD PMID:34122009 NCBI chr 8:122,501,938...122,519,600
Ensembl chr 8:122,502,218...122,519,600 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19917
    role 19887
      application 19729
        pharmaceutical 19563
          drug 19563
            antidyskinesia agent 1553
              benzatropine 329
                benzatropine mesylate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19917
    subatomic particle 19915
      composite particle 19915
        hadron 19915
          baryon 19915
            nucleon 19915
              atomic nucleus 19915
                atom 19915
                  main group element atom 19855
                    main group molecular entity 19855
                      s-block molecular entity 19686
                        hydrogen molecular entity 19667
                          hydrides 19173
                            inorganic hydride 18184
                              pnictogen hydride 18174
                                nitrogen hydride 18087
                                  azane 17893
                                    ammonia 17892
                                      organic amino compound 17892
                                        tertiary amino compound 10159
                                          benzatropine 329
                                            benzatropine mesylate 0
paths to the root