U2af2 (U2 small nuclear RNA auxiliary factor 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: U2af2 (U2 small nuclear RNA auxiliary factor 2) Rattus norvegicus
Analyze
Symbol: U2af2
Name: U2 small nuclear RNA auxiliary factor 2
RGD ID: 1310690
Description: Predicted to enable several functions, including C2H2 zinc finger domain binding activity; RNA binding activity; and enzyme binding activity. Predicted to be involved in negative regulation of protein ubiquitination; regulation of RNA splicing; and spliceosomal complex assembly. Predicted to be located in nucleus. Predicted to be part of Prp19 complex; U2-type spliceosomal complex; and U2AF complex. Predicted to be active in nuclear speck. Human ortholog(s) of this gene implicated in developmental delay, dysmorphic facies, and brain anomalies. Orthologous to human U2AF2 (U2 small nuclear RNA auxiliary factor 2); PARTICIPATES IN spliceosome pathway; INTERACTS WITH bisphenol A; cadmium dichloride; Cuprizon.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC308335; splicing factor U2AF 65 kDa subunit; U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8177,789,752 - 77,807,307 (-)NCBIGRCr8
mRatBN7.2168,760,911 - 68,779,730 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl168,760,924 - 68,778,492 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0172,312,260 - 72,329,828 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,312,727 - 72,329,856 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0176,206,254 - 76,223,269 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,498,102 - 67,517,118 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1167,576,224 - 67,595,267 (-)NCBI
Celera168,340,744 - 68,358,089 (+)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. The spliceosome: design principles of a dynamic RNP machine. Wahl MC, etal., Cell. 2009 Feb 20;136(4):701-18. doi: 10.1016/j.cell.2009.02.009.
Additional References at PubMed
PMID:1824937   PMID:2531895   PMID:9731529   PMID:9784496   PMID:12477932   PMID:15009664   PMID:19574390   PMID:21536736   PMID:21984414   PMID:22658674   PMID:22681889   PMID:24389012  
PMID:24912190   PMID:25002582   PMID:25931508  


Genomics

Comparative Map Data
U2af2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8177,789,752 - 77,807,307 (-)NCBIGRCr8
mRatBN7.2168,760,911 - 68,779,730 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl168,760,924 - 68,778,492 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0172,312,260 - 72,329,828 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,312,727 - 72,329,856 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0176,206,254 - 76,223,269 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,498,102 - 67,517,118 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1167,576,224 - 67,595,267 (-)NCBI
Celera168,340,744 - 68,358,089 (+)NCBICelera
Cytogenetic Map1q12NCBI
U2AF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381955,655,035 - 55,674,716 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1955,654,146 - 55,674,716 (+)EnsemblGRCh38hg38GRCh38
GRCh371956,166,401 - 56,186,082 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361960,857,228 - 60,877,894 (+)NCBINCBI36Build 36hg18NCBI36
Build 341960,857,227 - 60,877,893NCBI
Celera1953,207,708 - 53,228,376 (+)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1952,475,902 - 52,497,114 (+)NCBIHuRef
CHM1_11956,159,092 - 56,179,747 (+)NCBICHM1_1
T2T-CHM13v2.01958,750,963 - 58,771,692 (+)NCBIT2T-CHM13v2.0
U2af2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3975,063,884 - 5,082,937 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl75,065,142 - 5,082,937 (+)EnsemblGRCm39 Ensembl
GRCm3875,060,885 - 5,079,945 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl75,062,143 - 5,079,938 (+)EnsemblGRCm38mm10GRCm38
MGSCv3775,013,784 - 5,031,541 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3674,671,117 - 4,683,020 (+)NCBIMGSCv36mm8
Celera74,804,273 - 4,822,023 (+)NCBICelera
Cytogenetic Map7A1NCBI
cM Map72.93NCBI
U2af2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955567683,078 - 697,996 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955567683,472 - 699,105 (-)NCBIChiLan1.0ChiLan1.0
U2AF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22061,796,746 - 61,816,149 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11963,526,603 - 63,546,000 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01952,701,314 - 52,721,612 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11961,386,062 - 61,406,582 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1961,387,109 - 61,405,943 (+)Ensemblpanpan1.1panPan2
U2AF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11102,074,759 - 102,091,326 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1102,074,790 - 102,091,385 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1102,131,311 - 102,148,417 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01102,727,687 - 102,744,810 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1102,727,693 - 102,744,903 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11102,365,288 - 102,382,391 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01102,077,176 - 102,094,251 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01102,840,234 - 102,857,344 (-)NCBIUU_Cfam_GSD_1.0
U2af2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093491,703,829 - 1,721,065 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936981176,647 - 193,152 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936981176,552 - 193,798 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
U2AF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,774,078 - 59,789,395 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1659,773,205 - 59,789,403 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2654,726,514 - 54,733,246 (+)NCBISscrofa10.2Sscrofa10.2susScr3
U2AF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1648,244,247 - 48,265,029 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl648,245,297 - 48,265,019 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045901,415 - 922,138 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
U2af2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248321,747,642 - 1,761,112 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248321,747,237 - 1,762,080 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in U2af2
28 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:63
Count of miRNA genes:59
Interacting mature miRNAs:63
Transcripts:ENSRNOT00000021391
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14580314078430678Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13344984878449848Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)15389511782174945Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat

Markers in Region
RH125439  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21042,076,989 - 42,077,190 (+)MAPPERmRatBN7.2
mRatBN7.2168,761,087 - 68,761,288 (+)MAPPERmRatBN7.2
mRatBN7.21042,076,989 - 42,077,190 (-)MAPPERmRatBN7.2
mRatBN7.2168,761,087 - 68,761,288 (-)MAPPERmRatBN7.2
Rnor_6.0172,312,437 - 72,312,637NCBIRnor6.0
Rnor_6.01043,320,934 - 43,321,134NCBIRnor6.0
Rnor_5.01043,119,008 - 43,119,208UniSTSRnor5.0
Rnor_5.0176,223,753 - 76,223,953UniSTSRnor5.0
RGSC_v3.41043,489,634 - 43,489,834UniSTSRGSC3.4
RGSC_v3.4167,498,286 - 67,498,486UniSTSRGSC3.4
Celera1041,367,920 - 41,368,120UniSTS
Cytogenetic Map1q12UniSTS
U2AF2_7999  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21042,076,944 - 42,077,115 (-)MAPPERmRatBN7.2
Rnor_6.0172,312,512 - 72,312,941NCBIRnor6.0
Rnor_5.0176,223,136 - 76,223,878UniSTSRnor5.0
RGSC_v3.4167,498,361 - 67,499,548UniSTSRGSC3.4
Celera168,357,463 - 68,357,837UniSTS
Cytogenetic Map1q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000021391   ⟹   ENSRNOP00000021392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl168,760,924 - 68,778,492 (-)Ensembl
Rnor_6.0 Ensembl172,312,727 - 72,329,856 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104398   ⟹   ENSRNOP00000088416
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl168,760,924 - 68,776,888 (-)Ensembl
RefSeq Acc Id: NM_001427197   ⟹   NP_001414126
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8177,789,752 - 77,807,291 (-)NCBI
RefSeq Acc Id: NM_001427198   ⟹   NP_001414127
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8177,789,752 - 77,807,291 (-)NCBI
RefSeq Acc Id: XM_017589963   ⟹   XP_017445452
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8177,789,757 - 77,807,307 (-)NCBI
mRatBN7.2168,760,911 - 68,779,730 (-)NCBI
Rnor_6.0172,312,260 - 72,329,828 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017589964   ⟹   XP_017445453
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8177,789,757 - 77,807,307 (-)NCBI
mRatBN7.2168,760,911 - 68,779,730 (-)NCBI
Rnor_6.0172,312,260 - 72,329,828 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039100506   ⟹   XP_038956434
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8177,789,757 - 77,801,353 (-)NCBI
mRatBN7.2168,760,911 - 68,772,496 (-)NCBI
RefSeq Acc Id: XM_063288682   ⟹   XP_063144752
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8177,789,757 - 77,807,306 (-)NCBI
RefSeq Acc Id: XP_017445453   ⟸   XM_017589964
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A9Y1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017445452   ⟸   XM_017589963
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A9Y1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021392   ⟸   ENSRNOT00000021391
RefSeq Acc Id: XP_038956434   ⟸   XM_039100506
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000088416   ⟸   ENSRNOT00000104398
RefSeq Acc Id: NP_001414126   ⟸   NM_001427197
- UniProtKB: A6KNR7 (UniProtKB/TrEMBL),   A0A8I6A9Y1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001414127   ⟸   NM_001427198
- UniProtKB: A0A8I6A9Y1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144752   ⟸   XM_063288682
- Peptide Label: isoform X3
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F2Z3T9-F1-model_v2 AlphaFold F2Z3T9 1-471 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689700
Promoter ID:EPDNEW_R213
Type:initiation region
Name:U2af2_1
Description:U2 small nuclear RNA auxiliary factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0172,329,800 - 72,329,860EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310690 AgrOrtholog
BioCyc Gene G2FUF-60883 BioCyc
Ensembl Genes ENSRNOG00000015914 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021391.7 UniProtKB/TrEMBL
  ENSRNOT00000104398.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7320343 IMAGE-MGC_LOAD
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
  U2AF_lg UniProtKB/TrEMBL
MGC_CLONE MGC:109447 IMAGE-MGC_LOAD
NCBI Gene 308335 ENTREZGENE
PANTHER RNA-BINDING PROTEIN UniProtKB/TrEMBL
  SPLICING FACTOR U2AF 65 KDA SUBUNIT UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
PhenoGen U2af2 PhenoGen
PROSITE RRM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015914 RatGTEx
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A8I6A9Y1 ENTREZGENE, UniProtKB/TrEMBL
  A6KNR7 ENTREZGENE, UniProtKB/TrEMBL
  F2Z3T9_RAT UniProtKB/TrEMBL
  Q5EB64_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-07-09 U2af2  U2 small nuclear RNA auxiliary factor 2  U2af2  U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 U2af2  U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2  LOC690372  similar to U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform b  Data merged from RGD:1597319 1643240 APPROVED
2006-11-20 LOC690372  similar to U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform b      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 U2af2  U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2  U2af2_predicted  U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 U2af2_predicted  U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED