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Accession:CHEBI:3048 term browser browse the term
Definition:Tropane in which a hydrogen at position 3 is substituted by a diphenylmethoxy group (endo-isomer). An acetylcholine receptor antagonist, it is used (particularly as its methanesulphonate salt) in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments.
Synonyms:exact_synonym: (3-endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane
 related_synonym: 3alpha-(diphenylmethoxy)-1alphaH,5alphaH-tropane;   3alpha-(diphenylmethoxy)tropane;   3alpha-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane;   3endo-benzhydryloxytropane;   Benztropine;   Formula=C21H25NO;   InChI=1S/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19+,20+;   InChIKey=GIJXKZJWITVLHI-PMOLBWCYSA-N;   SMILES=[H][C@]1(C[C@]2([H])CC[C@]([H])(C1)N2C)OC(c1ccccc1)c1ccccc1;   benzatropina;   benzatropinum;   benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether;   tropine benzohydryl ether
 alt_id: CHEBI:661238
 xref: Beilstein:90688 "Beilstein";   CAS:86-13-5 "ChemIDplus";   CAS:86-13-5 "KEGG COMPOUND";   CAS:86-13-5 "NIST Chemistry WebBook";   DrugBank:DB00245;   Drug_Central:333 "DrugCentral";   KEGG:C06846;   KEGG:D07511
 xref_mesh: MESH:D001590
 xref: Patent:US2595405;   Wikipedia:Benzatropine

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benzatropine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb4 ATP binding cassette subfamily B member 4 JBrowse link 4 22,133,984 22,192,687 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Slc6a3 solute carrier family 6 member 3 JBrowse link 1 32,323,011 32,363,983 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      application 19308
        pharmaceutical 19179
          drug 19179
            antidyskinesia agent 1133
              benzatropine 4
                benzatropine mesylate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    main group molecular entity 19598
                      s-block molecular entity 19361
                        hydrogen molecular entity 19350
                          hydrides 18280
                            inorganic hydride 17204
                              pnictogen hydride 17166
                                nitrogen hydride 17003
                                  azane 16693
                                    ammonia 16690
                                      organic amino compound 16689
                                        tertiary amino compound 8527
                                          benzatropine 4
                                            benzatropine mesylate 0
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