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Gene: Erlin2 (ER lipid raft associated 2) Rattus norvegicus
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Symbol: Erlin2
Name: ER lipid raft associated 2
Description: Predicted to have cholesterol binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in SREBP signaling pathway; negative regulation of lipid biosynthetic process; and ubiquitin-dependent ERAD pathway. Predicted to localize to several cellular components, including the endoplasmic reticulum; endoplasmic reticulum membrane; and membrane raft. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 18. Orthologous to human ERLIN2 (ER lipid raft associated 2); INTERACTS WITH acrylamide; bisphenol A; Brodifacoum.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: endoplasmic reticulum lipid raft-associated protein 2; erlin-2; LOC290823; RGD1309010; similar to CDNA sequence BC036333; SPFH domain family, member 2; SPFH domain-containing protein 2; Spfh2; stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2
Orthologs:
Homo sapiens (human) : ERLIN2 (ER lipid raft associated 2)  HGNC  Alliance
Mus musculus (house mouse) : Erlin2 (ER lipid raft associated 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Erlin2 (ER lipid raft associated 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ERLIN2 (ER lipid raft associated 2)
Canis lupus familiaris (dog) : ERLIN2 (ER lipid raft associated 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Erlin2 (ER lipid raft associated 2)
Sus scrofa (pig) : ERLIN2 (ER lipid raft associated 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01669,179,005 - 69,195,452 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1669,179,588 - 69,195,097 (-)Ensembl
Rnor_5.01668,853,254 - 68,868,395 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41669,345,708 - 69,360,849 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11669,347,796 - 69,361,094 (-)NCBI
Celera1662,937,899 - 62,953,040 (-)NCBICelera
Cytogenetic Map16q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Erlin2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309010
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.