Kars1 (lysyl-tRNA synthetase 1) - Rat Genome Database

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Gene: Kars1 (lysyl-tRNA synthetase 1) Rattus norvegicus
Analyze
Symbol: Kars1 (Ensembl: Kars)
Name: lysyl-tRNA synthetase 1 (Ensembl:lysyl-tRNA synthetase)
RGD ID: 1359653
Description: Enables several functions, including ATP binding activity; lysine-tRNA ligase activity; and tRNA binding activity. Involved in several processes, including ERK1 and ERK2 cascade; diadenosine tetraphosphate biosynthetic process; and lysyl-tRNA aminoacylation. Located in cytosol and nucleus. Part of aminoacyl-tRNA synthetase multienzyme complex. Biomarker of sciatic neuropathy. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease recessive intermediate B and autosomal recessive nonsyndromic deafness 89. Orthologous to human KARS1 (lysyl-tRNA synthetase 1); PARTICIPATES IN aminoacyl-tRNA biosynthetic pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Kars; lysine--tRNA ligase; LysRS; lysyl-tRNA synthetase; MGC94484
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Candidate Gene For: Eau8
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21939,957,846 - 39,976,886 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1939,957,846 - 39,977,632 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1946,821,408 - 46,840,370 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01947,474,740 - 47,493,706 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01949,723,690 - 49,742,981 (-)NCBIRnor_WKY
Rnor_6.01944,212,205 - 44,231,209 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1944,212,206 - 44,231,157 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01955,018,815 - 55,037,820 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41941,927,508 - 41,946,461 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11941,932,389 - 41,951,342 (-)NCBI
Celera1939,318,292 - 39,337,236 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
aminoacyl-tRNA synthetase multienzyme complex  (IBA,IDA,ISO)
cytoplasm  (IDA,IEA)
cytosol  (IBA,IDA,ISO,ISS)
extracellular space  (IBA,ISO)
mitochondrion  (IBA,ISO)
nucleus  (IBA,IDA,ISO)
plasma membrane  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Characterization of a homogeneous complex of arginyl- and lysyl-tRNA synthetase: zinc and adenosine 5'-phosphate dependent synthesis of diadenosine 5',5'''-P1,P4-tetraphosphate. Hilderman RH Biochemistry. 1983 Sep 13;22(19):4353-7.
3. Characterization of a homogeneous arginyl- and lysyl-tRNA synthetase complex isolated from rat liver. Kinetic mechanism for lysyl-tRNA synthetase. Hilderman RH, etal., J Biol Chem. 1983 Nov 25;258(22):13592-6.
4. Purification and characterization of lysyl-tRNA synthetase after dissociation of the particulate aminoacyl-tRNA synthetases from rat liver. Johnson DL, etal., J Biol Chem. 1980 May 10;255(9):4362-6.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Expression profile of aminoacyl-tRNA synthetases in dorsal root ganglion neurons after peripheral nerve injury. Park BS, etal., J Mol Histol. 2015 Feb;46(1):115-22. doi: 10.1007/s10735-014-9601-4. Epub 2014 Dec 3.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
13. The human lysyl-tRNA synthetase gene encodes both the cytoplasmic and mitochondrial enzymes by means of an unusual alternative splicing of the primary transcript. Tolkunova E, etal., J Biol Chem 2000 Nov 10;275(45):35063-9.
14. Physical and biochemical characterization of a purified arginyl-tRNA synthetase-lysyl-tRNA-synthetase complex from rat liver. Van Dang C, etal., Biochemistry. 1982 Apr 13;21(8):1959-66.
15. [Study of the kinetics of thermoinactivation of lysyl-tRNA-synthetase from the liver of x-irradiated rats]. Verkhogliad IN, etal., Radiobiologiia. 1985 Mar-Apr;25(2):185-90.
16. Synthesis of diadenosine 5',5''' -P1,P4-tetraphosphate by lysyl-tRNA synthetase and a multienzyme complex of aminoacyl-tRNA synthetases from rat liver. Wahab SZ and Yang DC, J Biol Chem. 1985 May 10;260(9):5286-9.
17. LysRS serves as a key signaling molecule in the immune response by regulating gene expression. Yannay-Cohen N, etal., Mol Cell. 2009 Jun 12;34(5):603-11. doi: 10.1016/j.molcel.2009.05.019.
Additional References at PubMed
PMID:9278442   PMID:12060739   PMID:15851690   PMID:18272479   PMID:18614015   PMID:19131329   PMID:19289464   PMID:21536907   PMID:23159739   PMID:24212136  


Genomics

Comparative Map Data
Kars1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21939,957,846 - 39,976,886 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1939,957,846 - 39,977,632 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1946,821,408 - 46,840,370 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01947,474,740 - 47,493,706 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01949,723,690 - 49,742,981 (-)NCBIRnor_WKY
Rnor_6.01944,212,205 - 44,231,209 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1944,212,206 - 44,231,157 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01955,018,815 - 55,037,820 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41941,927,508 - 41,946,461 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11941,932,389 - 41,951,342 (-)NCBI
Celera1939,318,292 - 39,337,236 (-)NCBICelera
Cytogenetic Map19q12NCBI
KARS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381675,627,724 - 75,647,665 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1675,627,474 - 75,648,643 (-)EnsemblGRCh38hg38GRCh38
GRCh371675,661,622 - 75,681,563 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361674,219,131 - 74,239,078 (-)NCBINCBI36Build 36hg18NCBI36
Build 341674,219,130 - 74,239,078NCBI
Celera1659,955,969 - 59,975,930 (-)NCBICelera
Cytogenetic Map16q23.1NCBI
HuRef1661,415,299 - 61,435,262 (-)NCBIHuRef
CHM1_11677,074,018 - 77,093,985 (-)NCBICHM1_1
T2T-CHM13v2.01681,676,020 - 81,695,962 (-)NCBIT2T-CHM13v2.0
Kars
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398112,720,071 - 112,737,986 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8112,720,075 - 112,737,955 (-)EnsemblGRCm39 Ensembl
GRCm388111,993,439 - 112,011,354 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8111,993,443 - 112,011,323 (-)EnsemblGRCm38mm10GRCm38
MGSCv378114,517,340 - 114,535,205 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368114,880,116 - 114,897,941 (-)NCBIMGSCv36mm8
Celera8116,222,771 - 116,240,662 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map858.27NCBI
Kars1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554841,924,523 - 1,940,552 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554841,924,523 - 1,939,777 (+)NCBIChiLan1.0ChiLan1.0
KARS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11675,544,996 - 75,565,947 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1675,545,002 - 75,565,043 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01656,196,867 - 56,216,909 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
KARS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1575,172,976 - 75,188,197 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl575,173,032 - 75,188,197 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha575,150,330 - 75,165,555 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0575,486,891 - 75,502,304 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl575,486,958 - 75,502,304 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1575,423,065 - 75,438,308 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0575,258,329 - 75,273,495 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0575,749,065 - 75,764,469 (+)NCBIUU_Cfam_GSD_1.0
Kars1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934935,277,014 - 35,294,415 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647524,292,876 - 24,312,076 (-)EnsemblSpeTri2.0
SpeTri2.0NW_00493647524,294,699 - 24,312,051 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KARS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl612,056,571 - 12,073,748 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1612,057,475 - 12,073,749 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2611,898,371 - 11,914,646 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KARS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1561,113,215 - 61,133,093 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl561,113,213 - 61,132,995 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604714,926,869 - 14,946,419 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kars1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474611,337,529 - 11,353,797 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474611,337,505 - 11,354,950 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kars1
409 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:121
Count of miRNA genes:108
Interacting mature miRNAs:115
Transcripts:ENSRNOT00000046126
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)193383821455283146Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat

Markers in Region
RH144422  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21939,969,921 - 39,970,180 (+)MAPPERmRatBN7.2
Rnor_6.01944,224,277 - 44,224,535NCBIRnor6.0
Rnor_5.01955,030,887 - 55,031,145UniSTSRnor5.0
RGSC_v3.41941,939,581 - 41,939,839UniSTSRGSC3.4
Celera1939,330,359 - 39,330,617UniSTS
RH 3.4 Map19515.6UniSTS
Cytogenetic Map19q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000046126   ⟹   ENSRNOP00000044454
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1939,957,846 - 39,976,834 (-)Ensembl
Rnor_6.0 Ensembl1944,212,206 - 44,231,157 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117076   ⟹   ENSRNOP00000080260
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1939,957,849 - 39,977,632 (-)Ensembl
RefSeq Acc Id: NM_001006967   ⟹   NP_001006968
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21939,957,846 - 39,976,805 (-)NCBI
Rnor_6.01944,212,205 - 44,231,157 (-)NCBI
Rnor_5.01955,018,815 - 55,037,820 (-)NCBI
RGSC_v3.41941,927,508 - 41,946,461 (-)RGD
Celera1939,318,292 - 39,337,236 (-)RGD
Sequence:
RefSeq Acc Id: XM_006255630   ⟹   XP_006255692
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21939,957,870 - 39,976,886 (-)NCBI
Rnor_6.01944,212,205 - 44,231,209 (-)NCBI
Rnor_5.01955,018,815 - 55,037,820 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001006968   ⟸   NM_001006967
- UniProtKB: Q5XIM7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255692   ⟸   XM_006255630
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000044454   ⟸   ENSRNOT00000046126
RefSeq Acc Id: ENSRNOP00000080260   ⟸   ENSRNOT00000117076
Protein Domains
AA_TRNA_LIGASE_II

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIM7-F1-model_v2 AlphaFold Q5XIM7 1-626 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701158
Promoter ID:EPDNEW_R11682
Type:multiple initiation site
Name:Kars_1
Description:lysyl-tRNA synthetase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01944,231,169 - 44,231,229EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359653 AgrOrtholog
BioCyc Gene G2FUF-5634 BioCyc
BioCyc Pathway TRNA-CHARGING-PWY [tRNA charging] BioCyc
Ensembl Genes ENSRNOG00000019456 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000044454 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000080260 ENTREZGENE
  ENSRNOP00000080260.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046126 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000117076 ENTREZGENE
  ENSRNOT00000117076.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.930.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7135143 IMAGE-MGC_LOAD
InterPro aa-tRNA-synt_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  aa-tRNA-synth_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  aa-tRNA-synth_II/BPL/LPL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lys-tRNA-ligase_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lys-tRNA-ligase_II_bac/euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lys-tRNA-ligase_II_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lys-tRNA-synth_II_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NA-bd_OB_tRNA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:292028 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94484 IMAGE-MGC_LOAD
NCBI Gene 292028 ENTREZGENE
Pfam tRNA-synt_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  tRNA_anti-codon UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Kars1 PhenoGen
PIRSF LysRS2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS TRNASYNTHLYS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE AA_TRNA_LIGASE_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50249 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55681 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs lysS_bact UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZPX4 ENTREZGENE, UniProtKB/TrEMBL
  Q5XIM7 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-10-14 Kars1  lysyl-tRNA synthetase 1  Kars  lysyl-tRNA synthetase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Kars  lysyl-tRNA synthetase      Symbol and Name status set to approved 1299863 APPROVED
2005-07-29 Kars  lysyl-tRNA synthetase      Symbol and Name status set to provisional 70820 PROVISIONAL