CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Benzo[ghi]perylene
Accession: CHEBI:34568
browse the term
Definition: An ortho- and peri-fused polycyclic arene that has formula C22H12.
Synonyms: related_synonym: 1,12-Benzoperylene; Formula=C22H12; InChI=1S/C22H12/c1-3-13-7-9-15-11-12-16-10-8-14-4-2-6-18-17(5-1)19(13)21(15)22(16)20(14)18/h1-12H; InChIKey=GYFAGKUZYNFMBN-UHFFFAOYSA-N; SMILES=c1cc2ccc3ccc4ccc5cccc6c(c1)c2c3c4c56
xref: CAS:191-24-2; KEGG:C14318
xref_mesh: MESH:C006718
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Acadsb
acyl-CoA dehydrogenase, short/branched chain
increases expression
ISO
1,12-benzoperylene results in increased expression of ACADSB mRNA
CTD
PMID:26377693
NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379
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Acta1
actin, alpha 1, skeletal muscle
decreases expression
ISO
1,12-benzoperylene results in decreased expression of ACTA1 mRNA
CTD
PMID:26377693
NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742
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Acvr1b
activin A receptor type 1B
increases expression
ISO
1,12-benzoperylene results in increased expression of ACVR1B mRNA
CTD
PMID:26377693
NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673
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Adgrd1
adhesion G protein-coupled receptor D1
increases expression
ISO
1,12-benzoperylene results in increased expression of ADGRD1 mRNA
CTD
PMID:26377693
NCBI chr12:27,488,908...27,603,714
Ensembl chr12:27,488,908...27,603,696
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Adrb3
adrenoceptor beta 3
increases expression
ISO
1,12-benzoperylene results in increased expression of ADRB3 mRNA
CTD
PMID:26377693
NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
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Ahr
aryl hydrocarbon receptor
multiple interactions increases expression affects localization increases activity affects binding
ISO EXP
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene affects the localization of AHR protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene results in increased expression of AHR]; [1,12-benzoperylene co-treated with Benzo(a)pyrene] results in increased activity of AHR protein; [acenaphthene co-treated with anthracene co-treated with 1,12-benzoperylene co-treated with 1,2,5,6-dibenzanthracene co-treated with fluorene co-treated with naphthalene co-treated with phenanthrene] results in increased activity of AHR protein; AHR protein affects the reaction [1,12-benzoperylene results in increased expression of CDKN1B mRNA]; AHR protein affects the reaction [1,12-benzoperylene results in increased expression of NR2F1 mRNA]; AHR protein affects the reaction [1,12-benzoperylene results in increased expression of SOX9 mRNA]; AHR protein affects the reaction [NR2F1 protein affects the reaction [1,12-benzoperylene results in increased expression of SOX9 mRNA]]; NR2F1 protein affects the reaction [AHR protein affects the reaction [1,12-benzoperylene results in increased expression of SOX9 mRNA]] 1,12-benzoperylene results in increased expression of AHR; 1,12-benzoperylene results in increased expression of AHR mRNA 1,12-benzoperylene results in increased activity of AHR protein 1,12-benzoperylene binds to AHR protein
CTD
PMID:3024361 PMID:3028605 PMID:11141357 PMID:17665671 PMID:27234499 PMID:35182551 More...
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Aifm1
apoptosis inducing factor, mitochondria associated 1
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [1,12-benzoperylene results in increased expression of AIFM1 protein]
CTD
PMID:31518672
NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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Aip
aryl-hydrocarbon receptor-interacting protein
increases expression
ISO
1,12-benzoperylene results in increased expression of AIP mRNA
CTD
PMID:35182551
NCBI chr 1:201,408,002...201,419,220
Ensembl chr 1:201,407,288...201,419,122
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Aldh7a1
aldehyde dehydrogenase 7 family, member A1
increases expression
ISO
1,12-benzoperylene results in increased expression of ALDH7A1 mRNA
CTD
PMID:26377693
NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
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Anxa13
annexin A13
increases expression
ISO
1,12-benzoperylene results in increased expression of ANXA13 mRNA
CTD
PMID:26377693
NCBI chr 7:89,884,356...89,936,907
Ensembl chr 7:89,884,356...89,936,907
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Apln
apelin
increases expression
ISO
1,12-benzoperylene results in increased expression of APLN mRNA
CTD
PMID:26377693
NCBI chr X:127,180,801...127,213,567
Ensembl chr X:127,203,823...127,213,391
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Aplnr
apelin receptor
increases expression
ISO
1,12-benzoperylene results in increased expression of APLNR mRNA
CTD
PMID:26377693
NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050
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Aqp4
aquaporin 4
increases expression
ISO
1,12-benzoperylene results in increased expression of AQP4 mRNA
CTD
PMID:26377693
NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
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Arglu1
arginine and glutamate rich 1
decreases expression
ISO
1,12-benzoperylene results in decreased expression of ARGLU1 mRNA
CTD
PMID:26377693
NCBI chr16:80,753,300...80,777,350
Ensembl chr16:80,753,315...80,777,349
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Arhgap23
Rho GTPase activating protein 23
increases expression
ISO
1,12-benzoperylene results in increased expression of ARHGAP23 mRNA
CTD
PMID:26377693
NCBI chr10:82,437,578...82,496,846
Ensembl chr10:82,394,648...82,496,504
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Artn
artemin
increases expression
ISO
1,12-benzoperylene results in increased expression of ARTN mRNA
CTD
PMID:26377693
NCBI chr 5:131,458,596...131,470,193
Ensembl chr 5:131,464,756...131,468,025
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B3galt5
Beta-1,3-galactosyltransferase 5
increases expression
ISO
1,12-benzoperylene results in increased expression of B3GALT5 mRNA
CTD
PMID:26377693
NCBI chr11:35,584,273...35,630,922
Ensembl chr11:35,585,220...35,630,917
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Bckdha
branched chain keto acid dehydrogenase E1 subunit alpha
increases expression
ISO
1,12-benzoperylene results in increased expression of BCKDHA mRNA
CTD
PMID:26377693
NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862
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Bcl2l14
Bcl2-like 14
increases expression
ISO
1,12-benzoperylene results in increased expression of BCL2L14 mRNA
CTD
PMID:26377693
NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086
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Bhlha15
basic helix-loop-helix family, member a15
increases expression
ISO
1,12-benzoperylene results in increased expression of BHLHA15 mRNA
CTD
PMID:26377693
NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713
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Bpnt1
3'(2'), 5'-bisphosphate nucleotidase 1
increases expression
ISO
1,12-benzoperylene results in increased expression of BPNT1 mRNA
CTD
PMID:26377693
NCBI chr13:96,865,634...96,893,506
Ensembl chr13:96,868,580...96,893,503
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Brca2
BRCA2, DNA repair associated
increases expression
ISO
1,12-benzoperylene results in increased expression of BRCA2 mRNA
CTD
PMID:31518672
NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
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C1qtnf2
C1q and TNF related 2
increases expression
ISO
1,12-benzoperylene results in increased expression of C1QTNF2 mRNA
CTD
PMID:26377693
NCBI chr10:27,941,948...27,958,926
Ensembl chr10:27,941,948...27,959,185
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C2
complement C2
increases expression
ISO
1,12-benzoperylene results in increased expression of C2 mRNA
CTD
PMID:26377693
NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505
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C2cd4a
C2 calcium-dependent domain containing 4A
increases expression
ISO
1,12-benzoperylene results in increased expression of C2CD4A mRNA
CTD
PMID:26377693
NCBI chr 8:68,467,017...68,469,781
Ensembl chr 8:68,466,664...68,470,031
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C2cd4b
C2 calcium-dependent domain containing 4B
increases expression
ISO
1,12-benzoperylene results in increased expression of C2CD4B mRNA
CTD
PMID:26377693
NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328
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C4b
complement C4B
increases expression
ISO
1,12-benzoperylene results in increased expression of C4B mRNA
CTD
PMID:26377693
NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
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C9
complement C9
decreases expression
ISO
1,12-benzoperylene results in decreased expression of C9 mRNA
CTD
PMID:26377693
NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338
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Car3
carbonic anhydrase 3
decreases expression
ISO
1,12-benzoperylene results in decreased expression of CAR3 mRNA
CTD
PMID:26377693
NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
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Car6
carbonic anhydrase 6
decreases expression
ISO
1,12-benzoperylene results in decreased expression of CAR6 mRNA
CTD
PMID:26377693
NCBI chr 5:160,658,104...160,676,644
Ensembl chr 5:160,658,105...160,676,644
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Ccdc184
coiled-coil domain containing 184
increases expression
ISO
1,12-benzoperylene results in increased expression of CCDC184 mRNA
CTD
PMID:26377693
NCBI chr 7:129,297,635...129,301,961
Ensembl chr 7:129,298,212...129,304,494
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Cckar
cholecystokinin A receptor
increases expression
ISO
1,12-benzoperylene results in increased expression of CCKAR mRNA
CTD
PMID:26377693
NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747
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Ccl9
C-C motif chemokine ligand 9
increases expression
ISO
1,12-benzoperylene results in increased expression of CCL6 mRNA
CTD
PMID:26377693
NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
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Cdhr5
cadherin-related family member 5
increases expression
ISO
1,12-benzoperylene results in increased expression of CDHR5 mRNA
CTD
PMID:26377693
NCBI chr 1:196,373,110...196,381,609
Ensembl chr 1:196,373,112...196,381,543
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
1,12-benzoperylene results in increased expression of CDKN1A mRNA
CTD
PMID:26377693
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdkn1b
cyclin-dependent kinase inhibitor 1B
multiple interactions increases expression
ISO
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene results in increased expression of CDKN1B mRNA]; AHR protein affects the reaction [1,12-benzoperylene results in increased expression of CDKN1B mRNA]; NR2F1 protein affects the reaction [1,12-benzoperylene results in increased expression of CDKN1B mRNA] 1,12-benzoperylene results in increased expression of CDKN1B mRNA; 1,12-benzoperylene results in increased expression of CDKN1B protein
CTD
PMID:35182551
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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Cdkn2c
cyclin-dependent kinase inhibitor 2C
decreases expression
ISO
1,12-benzoperylene results in decreased expression of CDKN2C mRNA
CTD
PMID:26377693
NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
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Celf5
CUGBP, Elav-like family member 5
decreases expression
ISO
1,12-benzoperylene results in decreased expression of CELF5 mRNA
CTD
PMID:26377693
NCBI chr 7:8,225,787...8,250,322
Ensembl chr 7:8,225,825...8,250,322
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Ces2e
carboxylesterase 2E
increases expression
ISO
1,12-benzoperylene results in increased expression of CES2E mRNA
CTD
PMID:26377693
NCBI chr19:157,447...172,822
Ensembl chr19:157,407...172,856
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Ces2h
carboxylesterase 2H
increases expression
ISO
1,12-benzoperylene results in increased expression of CES2 mRNA
CTD
PMID:26377693
NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
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Chad
chondroadherin
increases expression
ISO
1,12-benzoperylene results in increased expression of CHAD mRNA
CTD
PMID:26377693
NCBI chr10:79,512,170...79,515,941
Ensembl chr10:79,511,931...79,515,940
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Chst8
carbohydrate sulfotransferase 8
increases expression
ISO
1,12-benzoperylene results in increased expression of CHST8 mRNA
CTD
PMID:26377693
NCBI chr 1:87,294,144...87,435,900
Ensembl chr 1:87,294,540...87,435,900
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Cish
cytokine inducible SH2-containing protein
decreases expression
ISO
1,12-benzoperylene results in decreased expression of CISH mRNA
CTD
PMID:26377693
NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
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Clca1
chloride channel accessory 1
increases expression
ISO
1,12-benzoperylene results in increased expression of CLCA1 mRNA
CTD
PMID:26377693
NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369
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Clic4
chloride intracellular channel 4
decreases expression
ISO
1,12-benzoperylene results in decreased expression of CLIC4 mRNA
CTD
PMID:26377693
NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
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Clptm1l
CLPTM1-like
increases expression
ISO
1,12-benzoperylene results in increased expression of CLPTM1L mRNA
CTD
PMID:26377693
NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530
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Cmtm8
CKLF-like MARVEL transmembrane domain containing 8
increases expression
ISO
1,12-benzoperylene results in increased expression of CMTM8 mRNA
CTD
PMID:26377693
NCBI chr 8:114,481,730...114,547,107
Ensembl chr 8:114,481,982...114,547,083
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Col12a1
collagen type XII alpha 1 chain
increases expression
ISO
1,12-benzoperylene results in increased expression of COL12A1 mRNA
CTD
PMID:26377693
NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686
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Col1a1
collagen type I alpha 1 chain
increases expression
ISO
1,12-benzoperylene results in increased expression of COL1A1 mRNA
CTD
PMID:26377693
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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Col5a3
collagen type V alpha 3 chain
increases expression
ISO
1,12-benzoperylene results in increased expression of COL5A3 mRNA
CTD
PMID:26377693
NCBI chr 8:19,304,564...19,349,809
Ensembl chr 8:19,304,571...19,349,853
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Cplx2
complexin 2
decreases expression
ISO
1,12-benzoperylene results in decreased expression of CPLX2 mRNA
CTD
PMID:26377693
NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
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Cpn1
carboxypeptidase N subunit 1
increases expression
ISO
1,12-benzoperylene results in increased expression of CPN1 mRNA
CTD
PMID:26377693
NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465
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Cpne5
copine 5
decreases expression
ISO
1,12-benzoperylene results in decreased expression of CPNE5 mRNA
CTD
PMID:26377693
NCBI chr20:7,206,742...7,289,309
Ensembl chr20:7,206,742...7,288,883
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Cpz
carboxypeptidase Z
increases expression
ISO
1,12-benzoperylene results in increased expression of CPZ mRNA
CTD
PMID:26377693
NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945
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Crb2
crumbs cell polarity complex component 2
increases expression
ISO
1,12-benzoperylene results in increased expression of CRB2 mRNA
CTD
PMID:26377693
NCBI chr 3:21,542,138...21,564,876
Ensembl chr 3:21,542,221...21,563,294
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Crebzf
CREB/ATF bZIP transcription factor
decreases expression
ISO
1,12-benzoperylene results in decreased expression of CREBZF mRNA
CTD
PMID:26377693
NCBI chr 1:144,416,864...144,423,540
Ensembl chr 1:144,417,446...144,428,553
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Cspp1
centrosome and spindle pole associated protein 1
increases expression
ISO
1,12-benzoperylene results in increased expression of CSPP1 mRNA
CTD
PMID:26377693
NCBI chr 5:9,077,161...9,192,402
Ensembl chr 5:9,077,161...9,193,377
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Cx3cr1
C-X3-C motif chemokine receptor 1
increases expression
ISO
1,12-benzoperylene results in increased expression of CX3CR1 mRNA
CTD
PMID:26377693
NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
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Cygb
cytoglobin
increases expression
ISO
1,12-benzoperylene results in increased expression of CYGB mRNA
CTD
PMID:26377693
NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions increases expression increases oxidation
ISO
[Benzo(a)pyrene co-treated with 1,12-benzoperylene] results in increased expression of CYP1A1 mRNA; [Benzo(a)pyrene co-treated with 1,12-benzoperylene] results in increased expression of CYP1A1 protein; [CYP1A1 protein results in increased oxidation of 1,12-benzoperylene] which results in increased abundance of 1,12-benzoperylene metabolite 1,12-benzoperylene results in increased expression of CYP1A1 protein 1,12-benzoperylene results in increased expression of CYP1A1 mRNA
CTD
PMID:11141357 PMID:17253728 PMID:23879290 PMID:26377693
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
multiple interactions increases expression increases oxidation
ISO
[CYP1B1 protein results in increased oxidation of 1,12-benzoperylene] which results in increased abundance of 1,12-benzoperylene metabolite 1,12-benzoperylene results in increased expression of CYP1B1 mRNA
CTD
PMID:23879290 PMID:27196671
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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Cyp2g1
cytochrome P450, family 2, subfamily g, polypeptide 1
increases expression
ISO
1,12-benzoperylene results in increased expression of CYP2G1 mRNA
CTD
PMID:26377693
NCBI chr 1:82,145,635...82,156,862
Ensembl chr 1:82,145,073...82,156,828
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Cyp4b1
cytochrome P450, family 4, subfamily b, polypeptide 1
increases expression multiple interactions
ISO
1,12-benzoperylene results in increased expression of CYP4B1 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene results in increased expression of CYP4B1]
CTD
PMID:27234499
NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
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Dbp
D-box binding PAR bZIP transcription factor
increases expression
ISO
1,12-benzoperylene results in increased expression of DBP mRNA
CTD
PMID:26377693
NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
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Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
1,12-benzoperylene results in increased expression of DDIT3 mRNA
CTD
PMID:35182551
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Ddx5
DEAD-box helicase 5
decreases expression
ISO
1,12-benzoperylene results in decreased expression of DDX5 mRNA
CTD
PMID:26377693
NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283
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Dido1
death inducer-obliterator 1
decreases expression
ISO
1,12-benzoperylene results in decreased expression of DIDO1 mRNA
CTD
PMID:26377693
NCBI chr 3:167,772,535...167,825,894
Ensembl chr 3:167,772,770...167,817,218
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Dmtf1
cyclin D binding myb-like transcription factor 1
decreases expression
ISO
1,12-benzoperylene results in decreased expression of DMTF1 mRNA
CTD
PMID:26377693
NCBI chr 4:24,909,937...24,950,786
Ensembl chr 4:24,910,534...24,950,967
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Dnaja1
DnaJ heat shock protein family (Hsp40) member A1
decreases expression
ISO
1,12-benzoperylene results in decreased expression of DNAJA1 mRNA
CTD
PMID:26377693
NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
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Dync2i1
dynein 2 intermediate chain 1
decreases expression
ISO
1,12-benzoperylene results in decreased expression of DYNC2I1 mRNA
CTD
PMID:26377693
NCBI chr 6:137,133,418...137,189,937
Ensembl chr 6:137,133,418...137,188,719
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Eif2ak3
eukaryotic translation initiation factor 2 alpha kinase 3
increases expression multiple interactions
ISO
1,12-benzoperylene results in increased expression of EIF2AK3 mRNA 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene results in increased expression of EIF2AK3 mRNA]; Cycloheximide inhibits the reaction [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene results in increased expression of EIF2AK3 mRNA]]
CTD
PMID:35182551
NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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Ep300
E1A binding protein p300
increases expression
ISO
1,12-benzoperylene results in increased expression of EP300 mRNA
CTD
PMID:35182551
NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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Epb41l5
erythrocyte membrane protein band 4.1 like 5
increases expression
ISO
1,12-benzoperylene results in increased expression of EPB41L5 mRNA
CTD
PMID:26377693
NCBI chr13:30,670,792...30,770,213
Ensembl chr13:30,669,764...30,768,360
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Erlec1
endoplasmic reticulum lectin 1
increases expression
ISO
1,12-benzoperylene results in increased expression of ERLEC1 mRNA
CTD
PMID:26377693
NCBI chr14:104,655,745...104,693,508
Ensembl chr14:104,655,673...104,693,480
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Espn
espin
increases expression
ISO
1,12-benzoperylene results in increased expression of ESPN mRNA
CTD
PMID:26377693
NCBI chr 5:162,626,560...162,660,439
Ensembl chr 5:162,626,560...162,660,256
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Esrrg
estrogen-related receptor gamma
increases expression
ISO
1,12-benzoperylene results in increased expression of ESRRG mRNA
CTD
PMID:26377693
NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
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Eva1a
eva-1 homolog A, regulator of programmed cell death
increases expression
ISO
1,12-benzoperylene results in increased expression of EVA1A mRNA
CTD
PMID:26377693
NCBI chr 4:114,593,773...114,643,011
Ensembl chr 4:114,593,341...114,643,011
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Farp1
FERM, ARH/RhoGEF and pleckstrin domain protein 1
decreases expression
ISO
1,12-benzoperylene results in decreased expression of FARP1 mRNA
CTD
PMID:26377693
NCBI chr15:98,124,304...98,363,299
Ensembl chr15:98,182,329...98,363,299
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Fkbp6
FKBP prolyl isomerase family member 6
increases expression
ISO
1,12-benzoperylene results in increased expression of FKBP6 mRNA
CTD
PMID:26377693
NCBI chr12:21,318,251...21,390,350
Ensembl chr12:21,319,568...21,390,350
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Fmo5
flavin containing dimethylaniline monoxygenase 5
affects expression
ISO
1,12-benzoperylene affects the expression of FMO5 mRNA
CTD
PMID:26377693
NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
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Fus
Fus RNA binding protein
increases expression
ISO
1,12-benzoperylene results in increased expression of FUS mRNA
CTD
PMID:26377693
NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414
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Fxyd5
FXYD domain-containing ion transport regulator 5
decreases expression
ISO
1,12-benzoperylene results in decreased expression of FXYD5 mRNA
CTD
PMID:26377693
NCBI chr 1:86,267,937...86,277,329
Ensembl chr 1:86,267,406...86,277,519
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Fzd6
frizzled class receptor 6
increases expression
ISO
1,12-benzoperylene results in increased expression of FZD6 mRNA
CTD
PMID:26377693
NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
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Gabra3
gamma-aminobutyric acid type A receptor subunit alpha 3
increases expression
ISO
1,12-benzoperylene results in increased expression of GABRA3 mRNA
CTD
PMID:26377693
NCBI chr X:150,244,745...150,501,566
Ensembl chr X:150,261,607...150,501,559
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Gadd45b
growth arrest and DNA-damage-inducible, beta
decreases expression
ISO
1,12-benzoperylene results in decreased expression of GADD45B mRNA
CTD
PMID:31518672
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
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Gas7
growth arrest specific 7
decreases expression
ISO
1,12-benzoperylene results in decreased expression of GAS7 mRNA
CTD
PMID:26377693
NCBI chr10:52,152,718...52,383,283
Ensembl chr10:52,152,493...52,383,276
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Gca
grancalcin
increases expression
ISO
1,12-benzoperylene results in increased expression of GCA mRNA
CTD
PMID:26377693
NCBI chr 3:47,297,320...47,329,913
Ensembl chr 3:47,297,383...47,328,581
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Gdf15
growth differentiation factor 15
increases expression
ISO
1,12-benzoperylene results in increased expression of GDF15 mRNA
CTD
PMID:26377693
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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Gdf9
growth differentiation factor 9
increases expression
ISO
1,12-benzoperylene results in increased expression of GDF9 mRNA
CTD
PMID:26377693
NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672
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Golph3l
golgi phosphoprotein 3-like
increases expression
ISO
1,12-benzoperylene results in increased expression of GOLPH3L mRNA
CTD
PMID:26377693
NCBI chr 2:183,151,941...183,183,094
Ensembl chr 2:183,153,301...183,183,083
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Gpa33
glycoprotein A33
increases expression
ISO
1,12-benzoperylene results in increased expression of GPA33 mRNA
CTD
PMID:26377693
NCBI chr13:78,381,141...78,414,765
Ensembl chr13:78,381,141...78,414,765
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Gper1
G protein-coupled estrogen receptor 1
increases expression
ISO
1,12-benzoperylene results in increased expression of GPER1 mRNA
CTD
PMID:26377693
NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
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Gpm6a
glycoprotein m6a
increases expression
ISO
1,12-benzoperylene results in increased expression of GPM6A mRNA
CTD
PMID:26377693
NCBI chr16:36,641,282...36,973,377
Ensembl chr16:36,641,284...36,973,475
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Grk3
G protein-coupled receptor kinase 3
increases expression
ISO
1,12-benzoperylene results in increased expression of GRK3 mRNA
CTD
PMID:26377693
NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262
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Gtf2b
general transcription factor IIB
increases expression
ISO
1,12-benzoperylene results in increased expression of GTF2B mRNA
CTD
PMID:35182551
NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651
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Gyg1
glycogenin 1
increases expression
ISO
1,12-benzoperylene results in increased expression of GYG1 mRNA
CTD
PMID:26377693
NCBI chr 2:102,611,888...102,653,916
Ensembl chr 2:102,598,496...102,653,797
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H1f1
H1.1 linker histone, cluster member
decreases expression
ISO
1,12-benzoperylene results in decreased expression of H1F1 mRNA
CTD
PMID:26377693
NCBI chr17:41,366,268...41,367,011
Ensembl chr17:41,366,268...41,367,011
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H2ax
H2A.X variant histone
increases expression increases phosphorylation multiple interactions
ISO
1,12-benzoperylene results in increased expression of H2AX protein 1,12-benzoperylene results in increased phosphorylation of H2AX protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene results in increased expression of H2AX protein]
CTD
PMID:31518672 PMID:35182551 PMID:37150498
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
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Herc3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
increases expression
ISO
1,12-benzoperylene results in increased expression of HERC3 mRNA
CTD
PMID:26377693
NCBI chr 4:87,952,202...88,042,492
Ensembl chr 4:87,952,274...88,042,488
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Hhex
hematopoietically expressed homeobox
decreases expression
ISO
1,12-benzoperylene results in decreased expression of HHEX mRNA
CTD
PMID:26377693
NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042
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Hook3
hook microtubule-tethering protein 3
affects expression
ISO
1,12-benzoperylene affects the expression of HOOK3 mRNA
CTD
PMID:26377693
NCBI chr16:65,954,293...66,058,812
Ensembl chr16:65,954,350...66,061,338
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Hoxc6
homeo box C6
decreases expression
ISO
1,12-benzoperylene results in decreased expression of HOXC6 mRNA
CTD
PMID:26377693
NCBI chr 7:134,138,017...134,148,899
Ensembl chr 7:134,135,502...134,148,392
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Hspa8
heat shock protein family A (Hsp70) member 8
decreases expression
ISO
1,12-benzoperylene results in decreased expression of HSPA8 mRNA
CTD
PMID:26377693
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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Hsph1
heat shock protein family H (Hsp110) member 1
decreases expression
ISO
1,12-benzoperylene results in decreased expression of HSPH1 mRNA
CTD
PMID:26377693
NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
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Hyal2
hyaluronidase 2
decreases expression
ISO
1,12-benzoperylene results in decreased expression of HYAL2 mRNA
CTD
PMID:26377693
NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850
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Ica1
islet cell autoantigen 1
increases expression
ISO
1,12-benzoperylene results in increased expression of ICA1 mRNA
CTD
PMID:26377693
NCBI chr 4:36,656,475...36,804,705
Ensembl chr 4:36,656,475...36,804,298
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Idh3a
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
increases expression
ISO
1,12-benzoperylene results in increased expression of IDH3A mRNA
CTD
PMID:26377693
NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
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Ier3
immediate early response 3
decreases expression
ISO
1,12-benzoperylene results in decreased expression of IER3 mRNA
CTD
PMID:26377693
NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
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Ifi27l2a
interferon, alpha-inducible protein 27 like 2A
decreases expression
ISO
1,12-benzoperylene results in decreased expression of IFI27L2A mRNA
CTD
PMID:26377693
NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360
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Igsf5
immunoglobulin superfamily, member 5
increases expression
ISO
1,12-benzoperylene results in increased expression of IGSF5 mRNA
CTD
PMID:26377693
NCBI chr11:35,686,513...35,729,396
Ensembl chr11:35,686,705...35,741,129
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Il12a
interleukin 12A
increases expression multiple interactions
ISO
1,12-benzoperylene results in increased expression of IL12A mRNA [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide co-treated with 1,12-benzoperylene] results in increased expression of IL12A mRNA
CTD
PMID:35182551
NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
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Il6
interleukin 6
increases expression multiple interactions
ISO
1,12-benzoperylene results in increased expression of IL6 mRNA [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide co-treated with 1,12-benzoperylene] results in increased expression of IL6 mRNA
CTD
PMID:35182551
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Inhba
inhibin subunit beta A
decreases expression
ISO
1,12-benzoperylene results in decreased expression of INHBA mRNA
CTD
PMID:26377693
NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
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Ino80b
INO80 complex subunit B
decreases expression
ISO
1,12-benzoperylene results in decreased expression of INO80B mRNA
CTD
PMID:26377693
NCBI chr 4:115,627,907...115,631,069
Ensembl chr 4:115,627,908...115,631,456
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Inpp5f
inositol polyphosphate-5-phosphatase F
decreases expression
ISO
1,12-benzoperylene results in decreased expression of INPP5F mRNA
CTD
PMID:26377693
NCBI chr 1:183,190,480...183,270,276
Ensembl chr 1:183,190,480...183,270,276
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Itpa
inosine triphosphatase
decreases expression
ISO
1,12-benzoperylene results in decreased expression of ITPA mRNA
CTD
PMID:26377693
NCBI chr 3:117,885,464...117,897,247
Ensembl chr 3:117,885,099...117,897,249
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Kcne3
potassium voltage-gated channel subfamily E regulatory subunit 3
increases expression
ISO
1,12-benzoperylene results in increased expression of KCNE3 mRNA
CTD
PMID:26377693
NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020
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Kcnk10
potassium two pore domain channel subfamily K member 10
increases expression
ISO
1,12-benzoperylene results in increased expression of KCNK10 mRNA
CTD
PMID:26377693
NCBI chr 6:117,690,052...117,826,120
Ensembl chr 6:117,694,222...117,825,695
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Kdf1
keratinocyte differentiation factor 1
increases expression
ISO
1,12-benzoperylene results in increased expression of KDF1 mRNA
CTD
PMID:26377693
NCBI chr 5:145,744,753...145,758,150
Ensembl chr 5:145,745,099...145,755,878
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Klk1
kallikrein 1
increases expression
ISO
1,12-benzoperylene results in increased expression of KLK1 mRNA
CTD
PMID:26377693
NCBI chr 1:94,642,644...94,646,760
Ensembl chr 1:94,642,687...94,646,754
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Lcn2
lipocalin 2
increases expression
ISO
1,12-benzoperylene results in increased expression of LCN2 mRNA
CTD
PMID:26377693
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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Lhx5
LIM homeobox 5
increases expression
ISO
1,12-benzoperylene results in increased expression of LHX5 mRNA
CTD
PMID:26377693
NCBI chr12:36,126,186...36,134,625
Ensembl chr12:36,126,186...36,134,625
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Loxl1
lysyl oxidase-like 1
increases expression
ISO
1,12-benzoperylene results in increased expression of LOXL1 mRNA
CTD
PMID:26377693
NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356
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Lrp4
LDL receptor related protein 4
increases expression
ISO
1,12-benzoperylene results in increased expression of LRP4 mRNA
CTD
PMID:26377693
NCBI chr 3:77,429,600...77,483,593
Ensembl chr 3:77,429,798...77,483,593
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Lrrc31
leucine rich repeat containing 31
increases expression
ISO
1,12-benzoperylene results in increased expression of LRRC31 mRNA
CTD
PMID:26377693
NCBI chr 2:112,702,844...112,725,431
Ensembl chr 2:112,700,136...112,724,322
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Lrrn4
leucine rich repeat neuronal 4
increases expression
ISO
1,12-benzoperylene results in increased expression of LRRN4 mRNA
CTD
PMID:26377693
NCBI chr 3:120,138,093...120,150,877
Ensembl chr 3:120,139,410...120,150,831
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Luc7l3
LUC7-like 3 pre-mRNA splicing factor
decreases expression
ISO
1,12-benzoperylene results in decreased expression of LUC7L3 mRNA
CTD
PMID:26377693
NCBI chr10:79,240,050...79,276,555
Ensembl chr10:79,240,563...79,276,538
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Mcfd2
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
increases expression
ISO
1,12-benzoperylene results in increased expression of MCFD2 mRNA
CTD
PMID:26377693
NCBI chr 6:7,274,469...7,285,841
Ensembl chr 6:7,274,469...7,285,841
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Mdm4
MDM4 regulator of p53
decreases expression
ISO
1,12-benzoperylene results in decreased expression of MDM4 mRNA
CTD
PMID:26377693
NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226
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Me3
malic enzyme 3
increases expression
ISO
1,12-benzoperylene results in increased expression of ME3 mRNA
CTD
PMID:26377693
NCBI chr 1:143,534,024...143,735,551
Ensembl chr 1:143,534,139...143,733,132
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Mgat2
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
decreases expression
ISO
1,12-benzoperylene results in decreased expression of MGAT2 mRNA
CTD
PMID:26377693
NCBI chr 6:87,656,360...87,658,849
Ensembl chr 6:87,656,349...87,658,177
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Mgp
matrix Gla protein
increases expression
ISO
1,12-benzoperylene results in increased expression of MGP mRNA
CTD
PMID:26377693
NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
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Mki67
marker of proliferation Ki-67
multiple interactions decreases expression increases expression
ISO
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene results in decreased expression of MKI67 protein]; Acetylcysteine inhibits the reaction [1,12-benzoperylene results in increased expression of MKI67 protein]
CTD
PMID:31518672 PMID:35182551
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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Mkks
MKKS centrosomal shuttling protein
decreases expression
ISO
1,12-benzoperylene results in decreased expression of MKKS mRNA
CTD
PMID:26377693
NCBI chr 3:124,201,877...124,221,142
Ensembl chr 3:124,201,877...124,220,162
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Mtmr3
myotubularin related protein 3
decreases expression
ISO
1,12-benzoperylene results in decreased expression of MTMR3 mRNA
CTD
PMID:26377693
NCBI chr14:79,340,523...79,460,947
Ensembl chr14:79,340,513...79,461,041
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Mvd
mevalonate diphosphate decarboxylase
decreases expression
ISO
1,12-benzoperylene results in decreased expression of MVD mRNA
CTD
PMID:26377693
NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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N4bp2l1
NEDD4 binding protein 2-like 1
increases expression
ISO
1,12-benzoperylene results in increased expression of N4BP2L1 mRNA
CTD
PMID:26377693
NCBI chr12:102,572...128,352
Ensembl chr12:102,573...127,257
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Ncoa1
nuclear receptor coactivator 1
increases expression
ISO
1,12-benzoperylene results in increased expression of NCOA1 mRNA
CTD
PMID:35182551
NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
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Ncoa2
nuclear receptor coactivator 2
increases expression
ISO
1,12-benzoperylene results in increased expression of NCOA2 mRNA
CTD
PMID:35182551
NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
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Ncoa3
nuclear receptor coactivator 3
increases expression
ISO
1,12-benzoperylene results in increased expression of NCOA3 mRNA
CTD
PMID:35182551
NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
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Ncor2
nuclear receptor co-repressor 2
increases expression
ISO
1,12-benzoperylene results in increased expression of NCOR2 mRNA
CTD
PMID:35182551
NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
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Neb
nebulin
increases expression
ISO
1,12-benzoperylene results in increased expression of NEB mRNA
CTD
PMID:26377693
NCBI chr 3:36,613,677...36,811,618
Ensembl chr 3:36,613,716...36,811,574
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Nedd8
NEDD8 ubiquitin like modifier
increases expression
ISO
1,12-benzoperylene results in increased expression of NEDD8 mRNA
CTD
PMID:35182551
NCBI chr15:29,153,556...29,165,575
Ensembl chr15:29,153,556...29,166,160
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Nfib
nuclear factor I/B
increases expression
ISO
1,12-benzoperylene results in increased expression of NFIB mRNA
CTD
PMID:26377693
NCBI chr 5:96,759,208...96,974,001
Ensembl chr 5:96,764,653...96,975,479
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Nfil3
nuclear factor, interleukin 3 regulated
decreases expression
ISO
1,12-benzoperylene results in decreased expression of NFIL3 mRNA
CTD
PMID:26377693
NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
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Nktr
natural killer cell triggering receptor
decreases expression
ISO
1,12-benzoperylene results in decreased expression of NKTR mRNA
CTD
PMID:26377693
NCBI chr 8:121,380,010...121,420,495
Ensembl chr 8:121,382,436...121,418,314
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Nop56
NOP56 ribonucleoprotein
decreases expression
ISO
1,12-benzoperylene results in decreased expression of NOP56 mRNA
CTD
PMID:26377693
NCBI chr 3:117,476,963...117,481,847
Ensembl chr 3:117,477,053...117,481,841
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Nr1d1
nuclear receptor subfamily 1, group D, member 1
increases expression
ISO
1,12-benzoperylene results in increased expression of NR1D1 mRNA
CTD
PMID:26377693
NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
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Nr2f1
nuclear receptor subfamily 2, group F, member 1
increases expression multiple interactions
ISO
1,12-benzoperylene results in increased expression of NR2F1 mRNA 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene results in increased expression of NR2F1 mRNA]; AHR protein affects the reaction [1,12-benzoperylene results in increased expression of NR2F1 mRNA]; AHR protein affects the reaction [NR2F1 protein affects the reaction [1,12-benzoperylene results in increased expression of SOX9 mRNA]]; NR2F1 protein affects the reaction [1,12-benzoperylene results in increased expression of CDKN1B mRNA]; NR2F1 protein affects the reaction [1,12-benzoperylene results in increased expression of SOX9 mRNA]; NR2F1 protein affects the reaction [AHR protein affects the reaction [1,12-benzoperylene results in increased expression of SOX9 mRNA]]
CTD
PMID:35182551
NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123
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Nrip1
nuclear receptor interacting protein 1
increases expression
ISO
1,12-benzoperylene results in increased expression of NRIP1 mRNA
CTD
PMID:35182551
NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
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Nrn1
neuritin 1
decreases expression
ISO
1,12-benzoperylene results in decreased expression of NRN1 mRNA
CTD
PMID:26377693
NCBI chr17:28,129,969...28,138,898
Ensembl chr17:28,129,977...28,138,896
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Nsa2
NSA2 ribosome biogenesis factor
decreases expression
ISO
1,12-benzoperylene results in decreased expression of NSA2 mRNA
CTD
PMID:26377693
NCBI chr 2:28,443,142...28,449,393
Ensembl chr 2:28,441,269...28,449,388
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Nuak2
NUAK family kinase 2
increases expression
ISO
1,12-benzoperylene results in increased expression of NUAK2 mRNA
CTD
PMID:26377693
NCBI chr13:43,753,454...43,770,604
Ensembl chr13:43,753,832...43,770,604
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Nucb2
nucleobindin 2
increases expression
ISO
1,12-benzoperylene results in increased expression of NUCB2 mRNA
CTD
PMID:26377693
NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
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Numb
NUMB, endocytic adaptor protein
decreases expression
ISO
1,12-benzoperylene results in decreased expression of NUMB mRNA
CTD
PMID:26377693
NCBI chr 6:103,431,400...103,553,422
Ensembl chr 6:103,431,400...103,553,354
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Obp2a
odorant binding protein 2A
increases expression
ISO
1,12-benzoperylene results in increased expression of OBP2A mRNA
CTD
PMID:26377693
NCBI chr 3:8,505,963...8,509,269
Ensembl chr 3:8,505,990...8,509,269
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Ovol3
ovo-like zinc finger 3
decreases expression
ISO
1,12-benzoperylene results in decreased expression of OVOL3 mRNA
CTD
PMID:26377693
NCBI chr 1:85,484,956...85,488,592
Ensembl chr 1:85,484,956...85,488,592
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Oxct1
3-oxoacid CoA transferase 1
increases expression
ISO
1,12-benzoperylene results in increased expression of OXCT1 mRNA
CTD
PMID:26377693
NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714
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Pamr1
peptidase domain containing associated with muscle regeneration 1
increases expression
ISO
1,12-benzoperylene results in increased expression of PAMR1 mRNA
CTD
PMID:26377693
NCBI chr 3:88,889,061...88,988,615
Ensembl chr 3:88,889,046...88,988,606
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Papss2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
increases expression
ISO
1,12-benzoperylene results in increased expression of PAPSS2 mRNA
CTD
PMID:26377693
NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331
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Parp1
poly (ADP-ribose) polymerase 1
increases cleavage
ISO
1,12-benzoperylene results in increased cleavage of PARP1 protein
CTD
PMID:21132278
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Pcnx1
pecanex 1
increases expression
ISO
1,12-benzoperylene results in increased expression of PCNX1 mRNA
CTD
PMID:26377693
NCBI chr 6:101,565,461...101,702,339
Ensembl chr 6:101,565,580...101,702,271
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Pcnx2
pecanex 2
increases expression
ISO
1,12-benzoperylene results in increased expression of PCNX2 mRNA
CTD
PMID:26377693
NCBI chr19:53,718,920...53,869,559
Ensembl chr19:53,718,655...53,871,364
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Pcsk2
proprotein convertase subtilisin/kexin type 2
increases expression
ISO
1,12-benzoperylene results in increased expression of PCSK2 mRNA
CTD
PMID:26377693
NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127
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Piezo2
piezo-type mechanosensitive ion channel component 2
increases expression
ISO
1,12-benzoperylene results in increased expression of PIEZO2 mRNA
CTD
PMID:26377693
NCBI chr18:56,468,449...56,844,984
Ensembl chr18:56,469,680...56,844,216
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Pik3c2g
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
increases expression
ISO
1,12-benzoperylene results in increased expression of PIK3C2G mRNA
CTD
PMID:26377693
NCBI chr 4:172,483,752...172,851,623
Ensembl chr 4:172,484,345...172,850,544
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Pip5k1a
phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha
decreases expression
ISO
1,12-benzoperylene results in decreased expression of PIP5K1A mRNA
CTD
PMID:26377693
NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598
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Pld6
phospholipase D family, member 6
increases expression
ISO
1,12-benzoperylene results in increased expression of PLD6 mRNA
CTD
PMID:26377693
NCBI chr10:44,578,536...44,581,187
Ensembl chr10:44,577,675...44,581,077
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Pnliprp1
pancreatic lipase-related protein 1
increases expression
ISO
1,12-benzoperylene results in increased expression of PNLIPRP1 mRNA
CTD
PMID:26377693
NCBI chr 1:257,867,885...257,883,514
Ensembl chr 1:257,867,885...257,883,514
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Pnliprp2
pancreatic lipase related protein 2
increases expression
ISO
1,12-benzoperylene results in increased expression of PNLIPRP2 mRNA
CTD
PMID:26377693
NCBI chr 1:257,897,766...257,916,434
Ensembl chr 1:257,897,766...257,916,434
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Polb
DNA polymerase beta
increases expression
ISO
1,12-benzoperylene results in increased expression of POLB mRNA
CTD
PMID:31518672
NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812
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Pold1
DNA polymerase delta 1, catalytic subunit
increases expression
ISO
1,12-benzoperylene results in increased expression of POLD1 mRNA
CTD
PMID:31518672
NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465
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Polg
DNA polymerase gamma, catalytic subunit
increases expression
ISO
1,12-benzoperylene results in increased expression of POLG mRNA
CTD
PMID:31518672
NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567
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Polr2a
RNA polymerase II subunit A
increases expression
ISO
1,12-benzoperylene results in increased expression of POLR2A mRNA
CTD
PMID:35182551
NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455
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Polr2b
RNA polymerase II subunit B
increases expression
ISO
1,12-benzoperylene results in increased expression of POLR2B mRNA
CTD
PMID:35182551
NCBI chr14:30,797,228...30,834,916
Ensembl chr14:30,797,228...30,834,916
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Polr2c
RNA polymerase II subunit C
increases expression
ISO
1,12-benzoperylene results in increased expression of POLR2C mRNA
CTD
PMID:31518672 PMID:35182551
NCBI chr19:10,158,153...10,164,935
Ensembl chr19:10,157,823...10,164,945
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Ppargc1a
PPARG coactivator 1 alpha
increases expression
ISO
1,12-benzoperylene results in increased expression of PPARGC1A mRNA
CTD
PMID:26377693
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
decreases expression
ISO
1,12-benzoperylene results in decreased expression of PREX2 mRNA
CTD
PMID:26377693
NCBI chr 5:7,937,692...8,253,112
Ensembl chr 5:7,942,573...8,253,068
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Prrx2
paired related homeobox 2
decreases expression
ISO
1,12-benzoperylene results in decreased expression of PRRX2 mRNA
CTD
PMID:26377693
NCBI chr 3:14,132,574...14,168,533
Ensembl chr 3:14,094,004...14,168,535
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Prss1
serine protease 1
increases expression
ISO
1,12-benzoperylene results in increased expression of PRSS1 mRNA
CTD
PMID:26377693
NCBI chr 4:70,364,589...70,367,792
Ensembl chr 4:70,364,586...70,367,792
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Prss3
serine protease 3
increases expression
ISO
1,12-benzoperylene results in increased expression of TRY4 mRNA
CTD
PMID:26377693
NCBI chr 4:70,203,088...70,206,562
Ensembl chr 4:70,203,088...70,206,562
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Pten
phosphatase and tensin homolog
decreases expression
ISO
1,12-benzoperylene results in decreased expression of PTEN mRNA
CTD
PMID:26377693
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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Ptges3
prostaglandin E synthase 3
increases expression
ISO
1,12-benzoperylene results in increased expression of PTGES3 mRNA
CTD
PMID:35182551
NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
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Rasef
RAS and EF hand domain containing
increases expression
ISO
1,12-benzoperylene results in increased expression of RASEF mRNA
CTD
PMID:26377693
NCBI chr 5:87,548,908...87,619,286
Ensembl chr 5:87,548,908...87,619,031
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Rb1
RB transcriptional corepressor 1
increases expression
ISO
1,12-benzoperylene results in increased expression of RB1 mRNA
CTD
PMID:35182551
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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Rbm15b
RNA binding motif protein 15B
decreases expression
ISO
1,12-benzoperylene results in decreased expression of RBM15B mRNA
CTD
PMID:26377693
NCBI chr 8:107,543,613...107,546,678
Ensembl chr 8:107,525,898...107,551,696
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Rbm3
RNA binding motif protein 3
increases expression
ISO
1,12-benzoperylene results in increased expression of RBM3 mRNA
CTD
PMID:26377693
NCBI chr X:14,348,909...14,352,387
Ensembl chr X:14,348,910...14,353,580
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Rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
increases expression
ISO
1,12-benzoperylene results in increased expression of RBPJL mRNA
CTD
PMID:26377693
NCBI chr 3:153,134,044...153,147,421
Ensembl chr 3:153,134,140...153,146,513
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Rela
RELA proto-oncogene, NF-kB subunit
increases expression
ISO
1,12-benzoperylene results in increased expression of RELA mRNA
CTD
PMID:35182551
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Rgs2
regulator of G-protein signaling 2
increases expression
ISO
1,12-benzoperylene results in increased expression of RGS2 mRNA
CTD
PMID:26377693
NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
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Rpl39l1
ribosomal protein L39 like 1
decreases expression
ISO
1,12-benzoperylene results in decreased expression of RPL39L mRNA
CTD
PMID:26377693
NCBI chr10:5,455,712...5,459,828
Ensembl chr10:5,454,559...5,462,029
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Rpp25
ribonuclease P and MRP subunit p25
increases expression
ISO
1,12-benzoperylene results in increased expression of RPP25 mRNA
CTD
PMID:26377693
NCBI chr 8:57,907,352...57,908,732
Ensembl chr 8:57,907,352...57,908,732
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Rps4y2
ribosomal protein S4, Y-linked 2
increases expression
ISO
1,12-benzoperylene results in increased expression of RPS4Y2 mRNA
CTD
PMID:26377693
NCBI chr 4:181,269,507...181,270,440
Ensembl chr 4:181,269,081...181,270,349
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Rsad2
radical S-adenosyl methionine domain containing 2
decreases expression
ISO
1,12-benzoperylene results in decreased expression of RSAD2 mRNA
CTD
PMID:26377693
NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
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Rspo1
R-spondin 1
increases expression
ISO
1,12-benzoperylene results in increased expression of RSPO1 mRNA
CTD
PMID:26377693
NCBI chr 5:137,251,629...137,273,273
Ensembl chr 5:137,251,659...137,272,933
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Rsrp1
arginine and serine rich protein 1
decreases expression
ISO
1,12-benzoperylene results in decreased expression of RSRP1 mRNA
CTD
PMID:26377693
NCBI chr 5:147,147,774...147,151,523
Ensembl chr 5:147,147,784...147,151,523
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RT1-Bb
RT1 class II, locus Bb
increases expression
ISO
1,12-benzoperylene results in increased expression of H2-AB1 mRNA
CTD
PMID:26377693
NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
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RT1-DMb
RT1 class II, locus DMb
increases expression
ISO
1,12-benzoperylene results in increased expression of H2-DMB1 mRNA
CTD
PMID:26377693
NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340
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RT1-DOb
RT1 class II, locus DOb
increases expression
ISO
1,12-benzoperylene results in increased expression of H2-OB mRNA
CTD
PMID:26377693
NCBI chr20:4,619,418...4,625,627
Ensembl chr20:4,619,816...4,625,667
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Rtp3
receptor (chemosensory) transporter protein 3
decreases expression
ISO
1,12-benzoperylene results in decreased expression of RTP3 mRNA
CTD
PMID:26377693
NCBI chr 8:110,970,154...110,975,000
Ensembl chr 8:110,970,160...110,974,699
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Scml4
Scm polycomb group protein like 4
increases expression
ISO
1,12-benzoperylene results in increased expression of SCML4 mRNA
CTD
PMID:26377693
NCBI chr20:46,347,350...46,441,246
Ensembl chr20:46,347,413...46,440,103
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Scn3a
sodium voltage-gated channel alpha subunit 3
increases expression
ISO
1,12-benzoperylene results in increased expression of SCN3A mRNA
CTD
PMID:26377693
NCBI chr 3:50,146,411...50,258,119
Ensembl chr 3:50,148,139...50,258,119
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Sctr
secretin receptor
increases expression
ISO
1,12-benzoperylene results in increased expression of SCTR mRNA
CTD
PMID:26377693
NCBI chr13:31,127,781...31,190,162
Ensembl chr13:31,127,858...31,180,189
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Sec16b
SEC16 homolog B, endoplasmic reticulum export factor
increases expression
ISO
1,12-benzoperylene results in increased expression of SEC16B mRNA
CTD
PMID:26377693
NCBI chr13:69,665,757...69,727,199
Ensembl chr13:69,684,291...69,727,196
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Sec23b
Sec23 homolog B, COPII coat complex component
increases expression
ISO
1,12-benzoperylene results in increased expression of SEC23B mRNA
CTD
PMID:26377693
NCBI chr 3:131,939,011...131,981,489
Ensembl chr 3:131,939,337...131,981,489
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Sema3d
semaphorin 3D
increases expression
ISO
1,12-benzoperylene results in increased expression of SEMA3D mRNA
CTD
PMID:26377693
NCBI chr 4:22,316,769...22,505,930
Ensembl chr 4:22,316,779...22,505,930
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Sfrp2
secreted frizzled-related protein 2
increases expression
ISO
1,12-benzoperylene results in increased expression of SFRP2 mRNA
CTD
PMID:26377693
NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
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Sfrp5
secreted frizzled-related protein 5
increases expression
ISO
1,12-benzoperylene results in increased expression of SFRP5 mRNA
CTD
PMID:26377693
NCBI chr 1:241,006,762...241,011,224
Ensembl chr 1:241,006,762...241,011,224
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Sgk2
serum/glucocorticoid regulated kinase 2
increases expression
ISO
1,12-benzoperylene results in increased expression of SGK2 mRNA
CTD
PMID:26377693
NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480
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Sgms2
sphingomyelin synthase 2
increases expression
ISO
1,12-benzoperylene results in increased expression of SGMS2 mRNA
CTD
PMID:26377693
NCBI chr 2:219,889,809...219,967,704
Ensembl chr 2:219,893,572...219,967,546
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Sh3d21
SH3 domain containing 21
increases expression
ISO
1,12-benzoperylene results in increased expression of SH3D21 mRNA
CTD
PMID:26377693
NCBI chr 5:138,429,180...138,444,540
Ensembl chr 5:138,429,180...138,444,407
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Shld2
shieldin complex subunit 2
decreases expression
ISO
1,12-benzoperylene results in decreased expression of SHLD2 mRNA
CTD
PMID:26377693
NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965
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Sidt1
SID1 transmembrane family, member 1
increases expression
ISO
1,12-benzoperylene results in increased expression of SIDT1 mRNA
CTD
PMID:26377693
NCBI chr11:56,362,788...56,459,939
Ensembl chr11:56,363,512...56,459,050
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Slc13a4
solute carrier family 13 member 4
decreases expression
ISO
1,12-benzoperylene results in decreased expression of SLC13A4 mRNA
CTD
PMID:26377693
NCBI chr 4:63,943,369...63,988,852
Ensembl chr 4:63,943,395...63,988,857
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Slc26a10
solute carrier family 26, member 10
increases expression
ISO
1,12-benzoperylene results in increased expression of SLC26A10 mRNA
CTD
PMID:26377693
NCBI chr 7:62,995,165...63,005,099
Ensembl chr 7:62,995,381...63,004,087
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Slc26a4
solute carrier family 26 member 4
increases expression
ISO
1,12-benzoperylene results in increased expression of SLC26A4 mRNA
CTD
PMID:26377693
NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703
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Slc44a4
solute carrier family 44, member 4
increases expression
ISO
1,12-benzoperylene results in increased expression of SLC44A4 mRNA
CTD
PMID:26377693
NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215
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Slc4a1
solute carrier family 4 member 1 (Diego blood group)
decreases expression
ISO
1,12-benzoperylene results in decreased expression of SLC4A1 mRNA
CTD
PMID:26377693
NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117
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Slc5a5
solute carrier family 5 member 5
increases expression
ISO
1,12-benzoperylene results in increased expression of SLC5A5 mRNA
CTD
PMID:26377693
NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697
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Slc9a4
solute carrier family 9 member A4
increases expression
ISO
1,12-benzoperylene results in increased expression of SLC9A4 mRNA
CTD
PMID:26377693
NCBI chr 9:42,825,334...42,879,729
Ensembl chr 9:42,825,064...42,879,422
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Smarca4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
increases expression
ISO
1,12-benzoperylene results in increased expression of SMARCA4 mRNA
CTD
PMID:35182551
NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
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Snap23
synaptosome associated protein 23
decreases expression
ISO
1,12-benzoperylene results in decreased expression of SNAP23 mRNA
CTD
PMID:26377693
NCBI chr 3:107,514,088...107,546,177
Ensembl chr 3:107,514,131...107,544,320
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Sned1
sushi, nidogen and EGF-like domains 1
increases expression
ISO
1,12-benzoperylene results in increased expression of SNED1 mRNA
CTD
PMID:26377693
NCBI chr 9:93,774,087...93,834,003
Ensembl chr 9:93,774,119...93,830,694
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Snhg11
small nucleolar RNA host gene 11
increases expression
ISO
1,12-benzoperylene results in increased expression of SNHG11 mRNA
CTD
PMID:26377693
NCBI chr 3:147,031,367...147,037,043
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Snrpf
small nuclear ribonucleoprotein polypeptide F
decreases expression
ISO
1,12-benzoperylene results in decreased expression of SNRPF mRNA
CTD
PMID:26377693
NCBI chr 7:28,130,427...28,137,129
Ensembl chr 7:28,130,427...28,137,129
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Sostdc1
sclerostin domain containing 1
increases expression
ISO
1,12-benzoperylene results in increased expression of SOSTDC1 mRNA
CTD
PMID:26377693
NCBI chr 6:53,051,336...53,055,510
Ensembl chr 6:53,051,354...53,055,579
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Sox9
SRY-box transcription factor 9
multiple interactions increases expression
ISO
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene results in increased expression of SOX9 mRNA]; AHR protein affects the reaction [1,12-benzoperylene results in increased expression of SOX9 mRNA]; AHR protein affects the reaction [NR2F1 protein affects the reaction [1,12-benzoperylene results in increased expression of SOX9 mRNA]]; NR2F1 protein affects the reaction [1,12-benzoperylene results in increased expression of SOX9 mRNA]; NR2F1 protein affects the reaction [AHR protein affects the reaction [1,12-benzoperylene results in increased expression of SOX9 mRNA]]
CTD
PMID:35182551
NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
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Sp1
Sp1 transcription factor
increases expression
ISO
1,12-benzoperylene results in increased expression of SP1 mRNA
CTD
PMID:35182551
NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
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Sp5
Sp5 transcription factor
increases expression
ISO
1,12-benzoperylene results in increased expression of SP5 mRNA
CTD
PMID:26377693
NCBI chr 3:55,274,931...55,277,733
Ensembl chr 3:55,274,931...55,277,733
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Spast
spastin
decreases expression
ISO
1,12-benzoperylene results in decreased expression of SPAST mRNA
CTD
PMID:26377693
NCBI chr 6:21,055,349...21,106,586
Ensembl chr 6:21,055,349...21,107,954
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Spon1
spondin 1
increases expression
ISO
1,12-benzoperylene results in increased expression of SPON1 mRNA
CTD
PMID:26377693
NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226
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Srrm1
serine and arginine repetitive matrix 1
decreases expression
ISO
1,12-benzoperylene results in decreased expression of SRRM1 mRNA
CTD
PMID:26377693
NCBI chr 5:147,559,515...147,591,895
Ensembl chr 5:147,559,514...147,591,849
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Srsf11
serine and arginine rich splicing factor 11
decreases expression
ISO
1,12-benzoperylene results in decreased expression of SRSF11 mRNA
CTD
PMID:26377693
NCBI chr 2:247,074,623...247,101,460
Ensembl chr 2:247,074,631...247,101,425
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Srsf5
serine and arginine rich splicing factor 5
increases expression
ISO
1,12-benzoperylene results in increased expression of SRSF5 mRNA
CTD
PMID:26377693
NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177
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St8sia6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
increases expression
ISO
1,12-benzoperylene results in increased expression of ST8SIA6 mRNA
CTD
PMID:26377693
NCBI chr17:76,740,755...76,884,178
Ensembl chr17:76,745,224...76,884,299
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Strbp
spermatid perinuclear RNA binding protein
increases expression
ISO
1,12-benzoperylene results in increased expression of STRBP mRNA
CTD
PMID:26377693
NCBI chr 3:21,328,310...21,467,753
Ensembl chr 3:21,337,855...21,414,949
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Sumo1
small ubiquitin-like modifier 1
increases expression
ISO
1,12-benzoperylene results in increased expression of SUMO1 mRNA
CTD
PMID:35182551
NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761
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Syn2
synapsin II
increases expression
ISO
1,12-benzoperylene results in increased expression of SYN2 mRNA
CTD
PMID:26377693
NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192
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Syt16
synaptotagmin 16
increases expression
ISO
1,12-benzoperylene results in increased expression of SYT16 mRNA
CTD
PMID:26377693
NCBI chr 6:92,721,415...92,972,140
Ensembl chr 6:92,721,101...92,971,748
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Sytl3
synaptotagmin-like 3
increases expression
ISO
1,12-benzoperylene results in increased expression of SYTL3 mRNA
CTD
PMID:26377693
NCBI chr 1:46,896,308...46,967,461
Ensembl chr 1:46,911,217...46,967,460
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Taf1
TATA-box binding protein associated factor 1
decreases expression
ISO
1,12-benzoperylene results in decreased expression of TAF1 mRNA
CTD
PMID:26377693
NCBI chr X:66,640,915...66,716,543
Ensembl chr X:66,640,982...66,716,543
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Tagln
transgelin
increases expression
ISO
1,12-benzoperylene results in increased expression of TAGLN mRNA
CTD
PMID:26377693
NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
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Tbc1d4
TBC1 domain family, member 4
increases expression
ISO
1,12-benzoperylene results in increased expression of TBC1D4 mRNA
CTD
PMID:26377693
NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265
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Tbp
TATA box binding protein
increases expression
ISO
1,12-benzoperylene results in increased expression of TBP mRNA
CTD
PMID:35182551
NCBI chr 1:56,463,330...56,480,430
Ensembl chr 1:56,463,618...56,510,016
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Tdrp
testis development related protein
increases expression
ISO
1,12-benzoperylene results in increased expression of TDRP mRNA
CTD
PMID:26377693
NCBI chr16:75,624,047...75,652,635
Ensembl chr16:75,624,907...75,652,420
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Tff3
trefoil factor 3
increases expression
ISO
1,12-benzoperylene results in increased expression of TFF3 mRNA
CTD
PMID:26377693
NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054
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Tgfb2
transforming growth factor, beta 2
increases expression
ISO
1,12-benzoperylene results in increased expression of TGFB2 mRNA
CTD
PMID:26377693
NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
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Tmed3
transmembrane p24 trafficking protein 3
increases expression
ISO
1,12-benzoperylene results in increased expression of TMED3 mRNA
CTD
PMID:26377693
NCBI chr 8:90,241,516...90,249,429
Ensembl chr 8:90,241,516...90,249,346
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Tmed6
transmembrane p24 trafficking protein 6
increases expression
ISO
1,12-benzoperylene results in increased expression of TMED6 mRNA
CTD
PMID:26377693
NCBI chr19:34,966,813...34,972,900
Ensembl chr19:34,966,813...34,972,900
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Tmem106b
transmembrane protein 106B
increases expression
ISO
1,12-benzoperylene results in increased expression of TMEM106B mRNA
CTD
PMID:26377693
NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619
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Tmem266
transmembrane protein 266
increases expression
ISO
1,12-benzoperylene results in increased expression of TMEM266 mRNA
CTD
PMID:26377693
NCBI chr 8:55,707,122...55,820,692
Ensembl chr 8:55,707,122...55,820,692
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Tmod3
tropomodulin 3
increases expression
ISO
1,12-benzoperylene results in increased expression of TMOD3 mRNA
CTD
PMID:26377693
NCBI chr 8:76,248,978...76,310,855
Ensembl chr 8:76,248,979...76,310,977
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Tmprss2
transmembrane serine protease 2
increases expression
ISO
1,12-benzoperylene results in increased expression of TMPRSS2 mRNA
CTD
PMID:26377693
NCBI chr11:36,934,306...36,973,779
Ensembl chr11:36,934,306...36,973,715
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Tnf
tumor necrosis factor
multiple interactions increases expression
ISO
[2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide co-treated with 1,12-benzoperylene] results in increased expression of TNF mRNA 1,12-benzoperylene results in increased expression of TNF mRNA
CTD
PMID:35182551
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnn
tenascin N
increases expression
ISO
1,12-benzoperylene results in increased expression of TNN mRNA
CTD
PMID:26377693
NCBI chr13:72,319,160...72,386,362
Ensembl chr13:72,319,155...72,408,156
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Tor1aip2
torsin 1A interacting protein 2
increases expression
ISO
1,12-benzoperylene results in increased expression of TOR1AIP2 mRNA
CTD
PMID:26377693
NCBI chr13:68,225,226...68,256,536
Ensembl chr13:68,230,009...68,256,536 Ensembl chr13:68,230,009...68,256,536
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Trem2
triggering receptor expressed on myeloid cells 2
increases expression
ISO
1,12-benzoperylene results in increased expression of TREM2 mRNA
CTD
PMID:26377693
NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
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Trim50
tripartite motif-containing 50
increases expression
ISO
1,12-benzoperylene results in increased expression of TRIM50 mRNA
CTD
PMID:26377693
NCBI chr12:21,300,784...21,317,668
Ensembl chr12:21,300,785...21,317,668
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Try5
trypsin 5
increases expression
ISO
1,12-benzoperylene results in increased expression of TRY5 mRNA
CTD
PMID:26377693
NCBI chr 4:70,213,760...70,217,034
Ensembl chr 4:70,213,756...70,217,051
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Tsc22d4
TSC22 domain family, member 4
increases expression
ISO
1,12-benzoperylene results in increased expression of TSC22D4 mRNA
CTD
PMID:26377693
NCBI chr12:18,939,150...18,952,008
Ensembl chr12:18,914,398...18,952,008
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Tspan18
tetraspanin 18
decreases expression
ISO
1,12-benzoperylene results in decreased expression of TSPAN18 mRNA
CTD
PMID:26377693
NCBI chr 3:79,160,060...79,299,907
Ensembl chr 3:79,161,662...79,299,852
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Tug1
taurine up-regulated 1
decreases expression
ISO
1,12-benzoperylene results in decreased expression of TUG1 mRNA
CTD
PMID:26377693
NCBI chr14:78,519,894...78,526,927
Ensembl chr14:78,522,506...78,526,927
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Txlng
taxilin gamma
increases expression
ISO
1,12-benzoperylene results in increased expression of TXLNG mRNA
CTD
PMID:26377693
NCBI chr X:31,864,111...31,912,931
Ensembl chr X:31,864,111...31,912,926
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Unc5a
unc-5 netrin receptor A
increases expression
ISO
1,12-benzoperylene results in increased expression of UNC5A mRNA
CTD
PMID:26377693
NCBI chr17:9,614,841...9,670,558
Ensembl chr17:9,614,838...9,670,526
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Upk3b
uroplakin 3B
increases expression
ISO
1,12-benzoperylene results in increased expression of UPK3B mRNA
CTD
PMID:26377693
NCBI chr12:20,630,231...20,637,634
Ensembl chr12:20,631,525...20,637,724
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Vps16
VPS16 core subunit of CORVET and HOPS complexes
decreases expression
ISO
1,12-benzoperylene results in decreased expression of VPS16 mRNA
CTD
PMID:26377693
NCBI chr 3:117,622,534...117,644,041
Ensembl chr 3:117,622,542...117,646,441
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Wnt10a
Wnt family member 10A
decreases expression
ISO
1,12-benzoperylene results in decreased expression of WNT10A mRNA
CTD
PMID:26377693
NCBI chr 9:76,349,931...76,362,400
Ensembl chr 9:76,349,931...76,362,400
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Wscd2
WSC domain containing 2
increases expression
ISO
1,12-benzoperylene results in increased expression of WSCD2 mRNA
CTD
PMID:26377693
NCBI chr12:43,046,547...43,141,115
Ensembl chr12:43,048,043...43,088,591
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Xrcc1
X-ray repair cross complementing 1
decreases expression
ISO
1,12-benzoperylene results in decreased expression of XRCC1 mRNA
CTD
PMID:31518672
NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
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Xrcc6
X-ray repair cross complementing 6
decreases expression increases expression
ISO
1,12-benzoperylene results in decreased expression of XRCC6 mRNA 1,12-benzoperylene results in increased expression of XRCC6 mRNA
CTD
PMID:31518672
NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762
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Zfp322a
zinc finger protein 322a
decreases expression
ISO
1,12-benzoperylene results in decreased expression of ZFP322A mRNA
CTD
PMID:26377693
NCBI chr17:41,773,789...41,789,654
Ensembl chr17:41,773,782...41,790,078
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