Cmtm8 (CKLF-like MARVEL transmembrane domain containing 8)

Gene: Cmtm8 (CKLF-like MARVEL transmembrane domain containing 8) Rattus norvegicus

Analyze

Symbol:

Cmtm8

Name:

CKLF-like MARVEL transmembrane domain containing 8

RGD ID:

735040

Description:

Predicted to be a structural constituent of myelin sheath. Predicted to be involved in myelination. Predicted to be located in nucleoplasm. Orthologous to human CMTM8 (CKLF like MARVEL transmembrane domain containing 8); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

chemokine-like factor super family 8; chemokine-like related protein 8; CKLF-like MARVEL transmembrane domain-containing protein 8; Cklfsf8; MGC108531

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	123,360,168 - 123,425,291 (-)	NCBI		GRCr8
mRatBN7.2	8	114,481,730 - 114,547,107 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	114,481,982 - 114,547,083 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	120,099,270 - 120,155,219 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	118,298,506 - 118,354,459 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	116,141,356 - 116,197,314 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	122,848,249 - 122,913,597 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	122,848,501 - 122,904,913 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	122,160,334 - 122,226,662 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	119,209,101 - 119,265,441 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	119,228,839 - 119,285,178 (-)	NCBI
Celera	8	113,728,864 - 113,785,306 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-diaminodiphenylmethane (ISO)

4-hydroxyphenyl retinamide (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

amphetamine (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

Benzo[ghi]perylene (ISO)

bisphenol A (EXP,ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

cisplatin (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

dioxygen (ISO)

diuron (EXP)

entinostat (ISO)

epoxiconazole (ISO)

fenthion (ISO)

gentamycin (EXP)

ketamine (EXP)

leflunomide (EXP)

methamphetamine (EXP)

methidathion (ISO)

methylmercury chloride (ISO)

nefazodone (EXP)

ochratoxin A (ISO)

paracetamol (EXP,ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

propiconazole (ISO)

protein kinase inhibitor (ISO)

rac-lactic acid (ISO)

rotenone (EXP)

silver atom (ISO)

silver(0) (ISO)

sodium dodecyl sulfate (ISO)

sunitinib (ISO)

temozolomide (ISO)

testosterone (EXP)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

trichloroethene (EXP)

triphenyl phosphate (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

myelination (IBA)

Cellular Component

membrane (IBA,IEA)

nucleoplasm (IEA,ISO)

Molecular Function

protein binding (ISO)

structural constituent of myelin sheath (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation.	Han W, etal., Genomics 2003 Jun;81(6):609-17.
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Cmtm8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	123,360,168 - 123,425,291 (-)	NCBI		GRCr8
mRatBN7.2	8	114,481,730 - 114,547,107 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	114,481,982 - 114,547,083 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	120,099,270 - 120,155,219 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	118,298,506 - 118,354,459 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	116,141,356 - 116,197,314 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	122,848,249 - 122,913,597 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	122,848,501 - 122,904,913 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	122,160,334 - 122,226,662 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	119,209,101 - 119,265,441 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	119,228,839 - 119,285,178 (-)	NCBI
Celera	8	113,728,864 - 113,785,306 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

CMTM8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	32,238,192 - 32,370,321 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	32,238,679 - 32,370,321 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	32,280,172 - 32,411,813 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	32,255,175 - 32,386,817 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	32,255,174 - 32,386,815	NCBI
Celera	3	32,217,566 - 32,349,242 (+)	NCBI		Celera
Cytogenetic Map	3	p22.3	NCBI
HuRef	3	32,215,225 - 32,347,344 (+)	NCBI		HuRef
CHM1_1	3	32,230,141 - 32,361,784 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	32,233,757 - 32,367,445 (+)	NCBI		T2T-CHM13v2.0

Cmtm8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	114,618,411 - 114,673,220 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	114,618,413 - 114,673,224 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	114,789,343 - 114,844,152 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	114,789,345 - 114,844,156 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	114,698,463 - 114,753,270 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	114,638,043 - 114,692,850 (-)	NCBI		MGSCv36	mm8
Celera	9	115,265,153 - 115,321,558 (-)	NCBI		Celera
Cytogenetic Map	9	F3	NCBI
cM Map	9	65.2	NCBI

Cmtm8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955430	23,638,734 - 23,728,365 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955430	23,638,734 - 23,728,365 (+)	NCBI	ChiLan1.0	ChiLan1.0

CMTM8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	32,212,966 - 32,347,275 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	32,217,730 - 32,352,042 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	32,153,673 - 32,287,746 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	32,472,720 - 32,602,124 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	32,472,794 - 32,601,767 (+)	Ensembl	panpan1.1		panPan2

CMTM8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	12,398,693 - 12,508,158 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	12,399,022 - 12,508,177 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	12,373,367 - 12,483,102 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	12,689,773 - 12,799,411 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	12,689,781 - 12,800,253 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	12,490,945 - 12,600,454 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	12,633,389 - 12,743,169 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	12,645,781 - 12,755,553 (-)	NCBI		UU_Cfam_GSD_1.0

Cmtm8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	189,636,929 - 189,736,092 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936473	22,775,502 - 22,875,023 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936473	22,775,503 - 22,874,665 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CMTM8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	18,243,471 - 18,350,091 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	18,243,379 - 18,350,386 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	20,414,847 - 20,549,120 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CMTM8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	76,748,254 - 76,873,970 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	76,748,220 - 76,874,262 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	50,102,098 - 50,227,956 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cmtm8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624788	10,333,342 - 10,417,228 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624788	10,333,314 - 10,417,228 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Cmtm8
453 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	212
Count of miRNA genes:	149
Interacting mature miRNAs:	161
Transcripts:	ENSRNOT00000015188
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	40952565	123900184	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	46531639	119088626	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	8	46531639	119088626	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	8	46531639	119088626	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	46531639	119088626	Rat
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	61290298	119084929	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	70513503	118219066	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	71888757	116888757	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	71888757	116888757	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	71888757	116888757	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	71888757	116888757	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	73473045	118473045	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	76468691	121468691	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	82460758	122812818	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	93535351	123900184	Rat
1358893	Bp263	Blood pressure QTL 263	5.01		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	93965141	123900184	Rat
1358903	Bp252	Blood pressure QTL 252	7	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	93965141	123900184	Rat
738014	Anxrr15	Anxiety related response QTL 15	3.6	0.005	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	95718998	123900184	Rat
2300182	Bmd56	Bone mineral density QTL 56	5.4		femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	95718998	123900184	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	100149864	120994388	Rat
1599689	Iddm24	Insulin dependent diabetes mellitus QTL 24	4.72	0.001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	8	112834440	118649220	Rat

Markers in Region

RH128745

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	114,482,021 - 114,482,241 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	122,848,541 - 122,848,760	NCBI	Rnor6.0
Rnor_5.0	8	122,160,626 - 122,160,845	UniSTS	Rnor5.0
RGSC_v3.4	8	119,209,143 - 119,209,362	UniSTS	RGSC3.4
Celera	8	113,728,906 - 113,729,125	UniSTS
Cytogenetic Map	8	q32	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	12	41	41		41			8	26	29	11
Low		31	16		19		8	11	66	9	12		8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_198754	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006243964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265300	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265301	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC122959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF538323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC088094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000015188 ⟹ ENSRNOP00000015188

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	114,481,982 - 114,538,402 (-)	Ensembl
Rnor_6.0 Ensembl	8	122,848,501 - 122,904,913 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000094177 ⟹ ENSRNOP00000092358

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	114,487,780 - 114,538,402 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000101305 ⟹ ENSRNOP00000077565

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	114,481,982 - 114,547,083 (-)	Ensembl

RefSeq Acc Id:

NM_198754 ⟹ NP_942049

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	123,360,168 - 123,416,584 (-)	NCBI
mRatBN7.2	8	114,481,980 - 114,538,402 (-)	NCBI
Rnor_6.0	8	122,848,499 - 122,904,913 (-)	NCBI
Rnor_5.0	8	122,160,334 - 122,226,662 (-)	NCBI
RGSC_v3.4	8	119,209,101 - 119,265,441 (-)	RGD
Celera	8	113,728,864 - 113,785,306 (-)	RGD

Sequence:

show sequence

CGGAGAGCTCTCAGTCCGCGGGAGACAGGTGCTGTGGCCGCGCGGCGGCGCCCCCGAGGGGAGG
TCCCCGAGTGCCCGCCCTCACCCGCCCTGTCTACGCCCCTCCCCTTTTCCCCTCCCCCGCTGTC
CGCAGCCACGGGTCGCCAGCGATCCCGCTCCCGGGTCCTGGAGCAAACCCGGAGTGCGCGCGTC
GACGTGTGGGGACACTCGCTGACCTGACCCTGGGGAATCACCCGGGTTTGCCCGCTTCCCATCA
GCCGCGATTCTCTGGCCTGCGACCCTGAGCCCAGGGAACTCATTTTGTGGGGGTAGGGTCCCCG
GGGACCCGGGCCAGCTCCCGGCGCGACCATGGAAGAGCAGCAGCGCGCGCGCTCGCACACGGTC
ACTACCACTTCCAGCTCCTTCGCGGAGAACTTCTCTACCACCAGCAGCAGCTTCGCTTACGACC
GAGAGTTCCTCCGCACCCCGCCAGGGCTCCTGATCATAGCTGAGATCGTCCTGGGACTGTTGGT
GTGGACGCTGATCGCTGGCACCGAGTATTTCCGAGTCCCTGCTTTTGGCTGGGTAATGTTTGTA
GCTGTCTTTTACTGGGTCCTCACCGTCTTCTTCCTCATTGTCTACATCACCATGACTTACACCA
GGATTCCCCAGGTGCCCTGGACCACAGTGGGCCTGTGCTTTAACGGCAGTGCCTGCGCCTTATA
CTTCTCAGCTGCCATAGTGGACGCGTCGTCTGTCTCCCCAGAGAAGGAAGGTCACAACTTCAAC
AGCTGGGCGGCCTCCTCGTTCTTTGCCTTCCTGGTCACCATCTGCTATGCTGGAAACACATACT
TCAGTTTCATAGCCTGGAGATCCAGGACCGCGCAGTGACGCTCCCTCCTCAGATAACGGAGAAG
AAGACACACACCAGGATGAATCCCACTGTTAAAACAAAACAAAAGACAGTTGTAGCTATAATGT
ATATTGCCCCAGAATTGTATTTAACTAAAGTTTTTATATCTTAGTTAAATTAGCTCTCAGTGTC
TCGTTACAGTTAAGCTGGATATTTACTTGGGGAGTGTTGTGGCTTCTAATGAATCCTGAGGTCT
CCTGATGTCCTCCTAGGCTTTATTTTCTTATACAATGTAAAAATAAATTGCTGAATGTTAAAAA
AAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006243964 ⟹ XP_006244026

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	123,360,168 - 123,425,284 (-)	NCBI
mRatBN7.2	8	114,481,730 - 114,547,107 (-)	NCBI
Rnor_6.0	8	122,848,249 - 122,913,597 (-)	NCBI
Rnor_5.0	8	122,160,334 - 122,226,662 (-)	NCBI

Sequence:

show sequence

CACCCGGCATTGGGAGGGCAGCACTGCTCACCCAGCACCTCAGACAGGAATTCAAACGTGGGCG
CCTAATGAACGCTAATGAGCAGAAGGTGTTGGCATCAGGACTGCCAGTTGAGCTTTGTTCCAAG
CCCTTCCTCCTGGCAGAACTTAAGACTTGGCAGTGCCACTAACAGGGCTTTCCAGACTGGTCCA
CTGGCATTCAGCAAGGTCCTGGGACTGTTGGTGTGGACGCTGATCGCTGGCACCGAGTATTTCC
GAGTCCCTGCTTTTGGCTGGGTAATGTTTGTAGCTGTCTTTTACTGGGTCCTCACCGTCTTCTT
CCTCATTGTCTACATCACCATGACTTACACCAGGATTCCCCAGGTGCCCTGGACCACAGTGGGC
CTGTGCTTTAACGGCAGTGCCTGCGCCTTATACTTCTCAGCTGCCATAGTGGACGCGTCGTCTG
TCTCCCCAGAGAAGGAAGGTCACAACTTCAACAGCTGGGCGGCCTCCTCGTTCTTTGCCTTCCT
GGTCACCATCTGCTATGCTGGAAACACATACTTCAGTTTCATAGCCTGGAGATCCAGGACCGCG
CAGTGACGCTCCCTCCTCAGATAACGGAGAAGAAGACACACACCAGGATGAATCCCACTGTTAA
AACAAAACAAAAGACAGTTGTAGCTATAATGTATATTGCCCCAGAATTGTATTTAACTAAAGTT
TTTATATCTTAGTTAAATTAGCTCTCAGTGTCTCGTTACAGTTAAGCTGGATATTTACTTGGGG
AGTGTTGTGGCTTCTAATGAATCCTGAGGTCTCCTGATGTCCTCCTAGGCTTTATTTTCTTATA
CAATGTAAAAATAAATTGCTGAATGTTAAGAAGGTGGAGTTTGTAAAGCTAACGCTTGAGATTA
CACTGGTTTCATGCATGTGTCCCTGGATGTGTGCTATGTATGGCTATGGGGGGCAGTGTGCAAC
TGAGGTCAGGAGTGAGTTCTCTCCTTCCGCCCTACATGTCCCAGGGATAAGATTCAGGGCTTCA
AGCTTGGCTTCAGGGTCCTCTGCCCACCAATCCATCTTACTGGCCCAAAGATAACTTTTCATTA
TGAAAATATATTTTGATTTTTAA

hide sequence

RefSeq Acc Id:

XM_063265300 ⟹ XP_063121370

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	123,360,168 - 123,419,253 (-)	NCBI

RefSeq Acc Id:

XM_063265301 ⟹ XP_063121371

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	123,360,168 - 123,425,291 (-)	NCBI

RefSeq Acc Id:

XM_063265302 ⟹ XP_063121372

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	123,360,168 - 123,415,949 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_942049	(Get FASTA)	NCBI Sequence Viewer
	XP_006244026	(Get FASTA)	NCBI Sequence Viewer
	XP_063121370	(Get FASTA)	NCBI Sequence Viewer
	XP_063121371	(Get FASTA)	NCBI Sequence Viewer
	XP_063121372	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH88094	(Get FASTA)	NCBI Sequence Viewer
	AAQ10889	(Get FASTA)	NCBI Sequence Viewer
	EDL76977	(Get FASTA)	NCBI Sequence Viewer
	EDL76978	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000015188
	ENSRNOP00000015188.4
	ENSRNOP00000077565
	ENSRNOP00000077565.1
	ENSRNOP00000092358.1

RefSeq Acc Id:	NP_942049 ⟸ NM_198754
- UniProtKB:	Q71B06 (UniProtKB/TrEMBL), F7F866 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEEQQRARSHTVTTTSSSFAENFSTTSSSFAYDREFLRTPPGLLIIAEIVLGLLVWTLIAGTEY FRVPAFGWVMFVAVFYWVLTVFFLIVYITMTYTRIPQVPWTTVGLCFNGSACALYFSAAIVDAS SVSPEKEGHNFNSWAASSFFAFLVTICYAGNTYFSFIAWRSRTAQ hide sequence

RefSeq Acc Id:	XP_006244026 ⟸ XM_006243964
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5Y7X1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSRRCWHQDCQLSFVPSPSSWQNLRLGSATNRAFQTGPLAFSKVLGLLVWTLIAGTEYFRVPAF GWVMFVAVFYWVLTVFFLIVYITMTYTRIPQVPWTTVGLCFNGSACALYFSAAIVDASSVSPEK EGHNFNSWAASSFFAFLVTICYAGNTYFSFIAWRSRTAQ hide sequence

RefSeq Acc Id:

ENSRNOP00000015188 ⟸ ENSRNOT00000015188

RefSeq Acc Id:

ENSRNOP00000077565 ⟸ ENSRNOT00000101305

RefSeq Acc Id:

ENSRNOP00000092358 ⟸ ENSRNOT00000094177

RefSeq Acc Id:	XP_063121371 ⟸ XM_063265301
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063121370 ⟸ XM_063265300
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063121372 ⟸ XM_063265302
- Peptide Label:	isoform X4

Protein Domains

MARVEL

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q71B06-F1-model_v2	AlphaFold	Q71B06	1-173	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:735040	AgrOrtholog
BioCyc Gene	G2FUF-28910	BioCyc
Ensembl Genes	ENSRNOG00000011201	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000015188	ENTREZGENE
	ENSRNOT00000015188.5	UniProtKB/TrEMBL
	ENSRNOT00000094177.1	UniProtKB/TrEMBL
	ENSRNOT00000101305.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7325894	IMAGE-MGC_LOAD
InterPro	MAL	UniProtKB/TrEMBL
	Marvel	UniProtKB/TrEMBL
KEGG Report	rno:301045	UniProtKB/TrEMBL
MGC_CLONE	MGC:108531	IMAGE-MGC_LOAD
NCBI Gene	301045	ENTREZGENE
PANTHER	CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 8	UniProtKB/TrEMBL
	MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN	UniProtKB/TrEMBL
Pfam	MARVEL	UniProtKB/TrEMBL
PhenoGen	Cmtm8	PhenoGen
PRINTS	MALPROTEIN	UniProtKB/TrEMBL
PROSITE	MARVEL	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000011201	RatGTEx
UniProt	A0A8I5Y7X1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ADT7_RAT	UniProtKB/TrEMBL
	A6I3Q0_RAT	UniProtKB/TrEMBL
	F7F866	ENTREZGENE, UniProtKB/TrEMBL
	Q71B06	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Cmtm8	CKLF-like MARVEL transmembrane domain containing 8	Cklfsf8	chemokine-like factor super family 8	Symbol and Name updated	1299863	APPROVED
2004-09-10	Cklfsf8	chemokine-like factor super family 8			Symbol and Name status set to approved	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar