Pik3c2g (phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma) - Rat Genome Database

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Gene: Pik3c2g (phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma) Rattus norvegicus
Analyze
Symbol: Pik3c2g
Name: phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
RGD ID: 620231
Description: Enables 1-phosphatidylinositol-3-kinase activity and 1-phosphatidylinositol-4-phosphate 3-kinase activity. Involved in phosphatidylinositol-3-phosphate biosynthetic process. Located in nuclear envelope. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PIK3C2G (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma); PARTICIPATES IN inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LRRG00132; phosphatidylinositol 3-kinase C2 domain-containing subunit gamma; phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma; phosphoinositide 3-Kinase-C2-gamma; phosphoinositide-3-kinase, class 2, gamma polypeptide; PI3K-C2-gamma; PI3K-C2gamma; ptdIns-3-kinase C2 gamma; ptdIns-3-kinase C2 subunit gamma
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84174,215,527 - 174,583,378 (+)NCBIGRCr8
mRatBN7.24172,483,752 - 172,851,623 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4172,484,345 - 172,850,544 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4178,779,339 - 179,145,536 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04174,563,498 - 174,929,713 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04173,184,038 - 173,550,261 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04173,732,196 - 174,102,502 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4173,732,248 - 174,102,496 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04237,973,381 - 238,271,814 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.04238,344,297 - 238,356,116 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44176,712,201 - 177,074,095 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14176,957,324 - 177,319,218 (+)NCBI
Celera4161,042,817 - 161,401,470 (+)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atazanavir sulfate  (ISO)
benzo[a]pyrene  (ISO)
Benzo[ghi]perylene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP)
cadmium dichloride  (EXP)
cantharidin  (ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
chlorpyrifos  (ISO)
cobalt dichloride  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
deoxycholic acid  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (EXP)
fenofibrate  (EXP)
flutamide  (EXP)
fructose  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
isotretinoin  (ISO)
methoxychlor  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
N-Nitrosopyrrolidine  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nickel dichloride  (EXP)
O-methyleugenol  (ISO)
oleanolic acid  (EXP)
paracetamol  (ISO)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
tartrazine  (ISO)
tetrachloromethane  (EXP)
tetracycline  (ISO)
thioacetamide  (EXP)
tipifarnib  (EXP)
trichloroethene  (EXP)
triclosan  (ISO)
triphenyl phosphate  (EXP)
valdecoxib  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Association of the PIK3C2G gene polymorphisms with type 2 DM in a Japanese population. Daimon M, etal., Biochem Biophys Res Commun. 2008 Jan 18;365(3):466-71. doi: 10.1016/j.bbrc.2007.10.180. Epub 2007 Nov 6.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. A novel class II phosphoinositide 3-kinase predominantly expressed in the liver and its enhanced expression during liver regeneration. Ono F, etal., J Biol Chem 1998 Mar 27;273(13):7731-6.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12464394   PMID:12482897   PMID:15362046   PMID:19376974   PMID:20536348  


Genomics

Comparative Map Data
Pik3c2g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84174,215,527 - 174,583,378 (+)NCBIGRCr8
mRatBN7.24172,483,752 - 172,851,623 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4172,484,345 - 172,850,544 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4178,779,339 - 179,145,536 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04174,563,498 - 174,929,713 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04173,184,038 - 173,550,261 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04173,732,196 - 174,102,502 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4173,732,248 - 174,102,496 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04237,973,381 - 238,271,814 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.04238,344,297 - 238,356,116 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44176,712,201 - 177,074,095 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14176,957,324 - 177,319,218 (+)NCBI
Celera4161,042,817 - 161,401,470 (+)NCBICelera
Cytogenetic Map4q44NCBI
PIK3C2G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381218,242,961 - 18,726,817 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1218,242,961 - 18,648,416 (+)EnsemblGRCh38hg38GRCh38
GRCh371218,414,452 - 18,801,350 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361218,305,741 - 18,692,617 (+)NCBINCBI36Build 36hg18NCBI36
Build 341218,305,740 - 18,692,615NCBI
Celera1223,559,670 - 23,946,872 (+)NCBICelera
Cytogenetic Map12p12.3NCBI
HuRef1218,182,567 - 18,569,771 (+)NCBIHuRef
CHM1_11218,379,684 - 18,766,393 (+)NCBICHM1_1
T2T-CHM13v2.01218,118,895 - 18,602,723 (+)NCBIT2T-CHM13v2.0
Pik3c2g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396139,591,070 - 139,915,010 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6139,564,219 - 139,915,010 (+)EnsemblGRCm39 Ensembl
GRCm386139,614,072 - 139,969,284 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6139,587,221 - 139,969,284 (+)EnsemblGRCm38mm10GRCm38
MGSCv376139,664,380 - 139,917,805 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv376139,562,593 - 139,605,759 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366139,678,267 - 139,931,692 (+)NCBIMGSCv36mm8
Celera6142,714,228 - 143,033,452 (+)NCBICelera
Cytogenetic Map6G2NCBI
cM Map669.7NCBI
Pik3c2g
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541314,454,377 - 14,764,558 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541314,454,376 - 14,764,323 (+)NCBIChiLan1.0ChiLan1.0
PIK3C2G
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21023,702,676 - 24,088,671 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11223,699,436 - 24,085,421 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01218,258,487 - 18,644,464 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11218,664,539 - 19,030,778 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1218,664,631 - 19,030,493 (+)Ensemblpanpan1.1panPan2
PIK3C2G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12728,446,629 - 28,818,198 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2728,424,899 - 28,796,902 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2717,634,256 - 18,004,900 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02728,777,707 - 29,148,879 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2728,777,942 - 29,120,607 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12728,624,760 - 28,982,990 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02728,617,093 - 28,982,011 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02717,346,838 - 17,712,725 (+)NCBIUU_Cfam_GSD_1.0
Pik3c2g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494589,681,373 - 90,001,143 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365487,604,404 - 7,856,872 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365487,604,272 - 7,923,984 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIK3C2G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl554,474,622 - 54,849,512 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1554,474,623 - 54,849,520 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2557,747,735 - 58,146,257 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIK3C2G
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11118,099,328 - 18,500,030 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1118,118,717 - 18,499,985 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606916,715,340 - 17,100,145 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pik3c2g
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475219,876,933 - 20,212,907 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475219,878,095 - 20,212,872 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pik3c2g
2389 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:16
Count of miRNA genes:15
Interacting mature miRNAs:16
Transcripts:ENSRNOT00000041499
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4146565735175236377Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
1300109Rf13Renal function QTL 133.91renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)4157710145182687754Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4155561574182687754Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat

Markers in Region
D4Got275  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24172,674,773 - 172,675,015 (+)MAPPERmRatBN7.2
Rnor_6.04173,928,221 - 173,928,462NCBIRnor6.0
Rnor_5.04238,164,878 - 238,165,119UniSTSRnor5.0
RGSC_v3.44176,903,911 - 176,904,152UniSTSRGSC3.4
Celera4161,228,714 - 161,228,955UniSTS
Cytogenetic Map4q44UniSTS
BE113549  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24172,486,558 - 172,486,715 (+)MAPPERmRatBN7.2
Rnor_6.04173,734,462 - 173,734,618NCBIRnor6.0
Rnor_5.04237,975,595 - 237,975,751UniSTSRnor5.0
RGSC_v3.44176,714,415 - 176,714,571UniSTSRGSC3.4
Celera4161,045,031 - 161,045,187UniSTS
RH 3.4 Map41031.7UniSTS
Cytogenetic Map4q44UniSTS
RH137861  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24172,522,615 - 172,522,754 (+)MAPPERmRatBN7.2
Rnor_6.04173,770,513 - 173,770,651NCBIRnor6.0
Rnor_5.04238,011,653 - 238,011,791UniSTSRnor5.0
RGSC_v3.44176,750,473 - 176,750,611UniSTSRGSC3.4
Celera4161,081,066 - 161,081,204UniSTS
RH 3.4 Map41033.6UniSTS
Cytogenetic Map4q44UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8 8 8
Low 1 7 34 33 1 33 8 27 4
Below cutoff 2 26 10 18 8 10 50 30 12 7 8

Sequence


RefSeq Acc Id: ENSRNOT00000041499   ⟹   ENSRNOP00000043855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4172,484,345 - 172,850,544 (+)Ensembl
Rnor_6.0 Ensembl4173,732,248 - 174,102,496 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000078963   ⟹   ENSRNOP00000071128
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4172,722,676 - 172,737,935 (+)Ensembl
RefSeq Acc Id: NM_053923   ⟹   NP_446375
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,215,527 - 174,581,708 (+)NCBI
mRatBN7.24172,484,345 - 172,850,547 (+)NCBI
Rnor_6.04173,732,248 - 174,102,499 (+)NCBI
Rnor_5.04237,973,381 - 238,271,814 (+)NCBI
Rnor_5.04238,344,297 - 238,356,116 (+)NCBI
RGSC_v3.44176,712,201 - 177,074,095 (+)RGD
Celera4161,042,817 - 161,401,470 (+)RGD
Sequence:
RefSeq Acc Id: XM_039106948   ⟹   XP_038962876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,252,810 - 174,583,378 (+)NCBI
mRatBN7.24172,483,758 - 172,851,623 (+)NCBI
RefSeq Acc Id: XR_005503143
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,252,810 - 174,371,605 (+)NCBI
mRatBN7.24172,483,752 - 172,640,505 (+)NCBI
RefSeq Acc Id: XR_010065609
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,252,810 - 174,371,677 (+)NCBI
RefSeq Acc Id: NP_446375   ⟸   NM_053923
- UniProtKB: O70173 (UniProtKB/Swiss-Prot),   A6IMM4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000043855   ⟸   ENSRNOT00000041499
RefSeq Acc Id: XP_038962876   ⟸   XM_039106948
- Peptide Label: isoform X1
- UniProtKB: D3ZE56 (UniProtKB/TrEMBL),   A6IMM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000071128   ⟸   ENSRNOT00000078963
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O70173-F1-model_v2 AlphaFold O70173 1-1505 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693476
Promoter ID:EPDNEW_R3999
Type:initiation region
Name:Pik3c2g_1
Description:phosphatidylinositol-4-phosphate 3-kinase, catalytic subunittype 2 gamma
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04173,732,235 - 173,732,295EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620231 AgrOrtholog
BioCyc Gene G2FUF-42549 BioCyc
Ensembl Genes ENSRNOG00000034228 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041499 ENTREZGENE
  ENSRNOT00000041499.5 UniProtKB/TrEMBL
  ENSRNOT00000078963.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1070.11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.40.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.1520.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA/RNA_pol_sf UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phox UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3/4_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3/4_kinase_cat_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3/4_kinase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_accessory_dom UniProtKB/TrEMBL
  PI3K_accessory_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_C2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_Ras-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI_Kinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PInositide-3_kin_accessory_dom UniProtKB/Swiss-Prot
  PX_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RT_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:116720 UniProtKB/Swiss-Prot
NCBI Gene 116720 ENTREZGENE
PANTHER LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN UniProtKB/TrEMBL
  PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT GAMMA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10048 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  REVERSE TRANSCRIPTASES UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00787 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3_PI4_kinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_rbd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3Ka UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RVT_1 UniProtKB/TrEMBL
PhenoGen Pik3c2g PhenoGen
PROSITE PI3_4_KINASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3_4_KINASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3_4_KINASE_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_RBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PIK_HELICAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50004 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50195 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RT_POL UniProtKB/TrEMBL
RatGTEx ENSRNOG00000034228 RatGTEx
SMART PI3K_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3Ka UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3Kc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00239 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00312 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49562 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56672 UniProtKB/TrEMBL
  SSF64268 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JZP4_RAT UniProtKB/TrEMBL
  A6IMM4 ENTREZGENE, UniProtKB/TrEMBL
  A6IMM5_RAT UniProtKB/TrEMBL
  D3ZE56 ENTREZGENE, UniProtKB/TrEMBL
  O70173 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-10 Pik3c2g  phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma  Pik3c2g  phosphoinositide-3-kinase, class 2, gamma polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Pik3c2g  phosphoinositide-3-kinase, class 2, gamma polypeptide  Pik3c2g  phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Pik3c2g  phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Pik3c2g  phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expression increases during liver regeneration with peak expression after the growth period 729517