RT1-DOb (RT1 class II, locus DOb) - Rat Genome Database

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Gene: RT1-DOb (RT1 class II, locus DOb) Rattus norvegicus
Analyze
Symbol: RT1-DOb
Name: RT1 class II, locus DOb
RGD ID: 1595814
Description: Predicted to enable MHC class II protein complex binding activity and peptide antigen binding activity. Predicted to be involved in several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; negative regulation of antigen processing and presentation of peptide antigen via MHC class II; and peptide antigen assembly with MHC class II protein complex. Predicted to be located in lysosome. Predicted to be part of MHC class II protein complex. Predicted to be active in late endosome membrane and lysosomal membrane. Orthologous to human HLA-DOB (major histocompatibility complex, class II, DO beta); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; asthma pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DOb; H2-Ob; histocompatibility 2, O region beta locus; RT1 class II, DO beta; RT1 class II, locus DOb (mapped); RT1-Bb2; RT1-DOb_mapped
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,621,336 - 4,627,537 (-)NCBIGRCr8
mRatBN7.2204,619,418 - 4,625,627 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,619,816 - 4,625,667 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx205,372,193 - 5,377,744 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,733,934 - 4,739,485 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0205,217,240 - 5,222,903 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,020,273 - 4,026,398 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,020,317 - 4,026,346 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,099,866 - 6,105,845 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,753,940 - 4,759,648 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera206,221,090 - 6,226,692 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:3865893   PMID:8890155   PMID:9492004   PMID:9601947   PMID:11685465   PMID:22733780   PMID:24586191  


Genomics

Comparative Map Data
RT1-DOb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,621,336 - 4,627,537 (-)NCBIGRCr8
mRatBN7.2204,619,418 - 4,625,627 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,619,816 - 4,625,667 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx205,372,193 - 5,377,744 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,733,934 - 4,739,485 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0205,217,240 - 5,222,903 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,020,273 - 4,026,398 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,020,317 - 4,026,346 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,099,866 - 6,105,845 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,753,940 - 4,759,648 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera206,221,090 - 6,226,692 (-)NCBICelera
Cytogenetic Map20p12NCBI
HLA-DOB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,812,763 - 32,817,002 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl632,812,763 - 32,820,466 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,780,540 - 32,784,779 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,888,518 - 32,892,803 (-)NCBINCBI36Build 36hg18NCBI36
Build 34632,888,526 - 32,892,760NCBI
Celera634,329,595 - 34,333,880 (-)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef632,522,917 - 32,527,179 (-)NCBIHuRef
CHM1_1632,781,544 - 32,785,829 (-)NCBICHM1_1
T2T-CHM13v2.0632,634,117 - 32,638,355 (-)NCBIT2T-CHM13v2.0
H2-Ob
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,457,879 - 34,464,882 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,457,877 - 34,473,388 (+)EnsemblGRCm39 Ensembl
GRCm381734,238,905 - 34,245,908 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,238,903 - 34,254,414 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,375,850 - 34,382,853 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361733,850,628 - 33,854,100 (+)NCBIMGSCv36mm8
Celera1736,980,110 - 36,996,885 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
LOC100970847
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2547,287,076 - 47,299,056 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1643,158,633 - 43,171,752 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0632,381,463 - 32,387,377 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1633,497,199 - 33,501,542 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl633,497,652 - 33,501,451 (-)Ensemblpanpan1.1panPan2
DLA-DOB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1122,376,957 - 2,384,179 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl122,378,126 - 2,432,303 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,459,974 - 2,465,584 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0122,652,367 - 2,659,185 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl122,652,372 - 2,699,034 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1122,377,490 - 2,383,108 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0122,458,767 - 2,464,390 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0122,533,116 - 2,538,741 (-)NCBIUU_Cfam_GSD_1.0
LOC101961309
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494638,022,484 - 38,035,492 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647625,932,968 - 25,936,593 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647625,932,926 - 25,937,024 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLA-DOB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl725,030,438 - 25,037,962 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1725,030,435 - 25,038,196 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2729,242,473 - 29,249,542 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap7q1.1NCBI
MHC-DOB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11739,295,768 - 39,300,032 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1739,295,828 - 39,300,819 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604432,593,845 - 32,598,586 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101702636
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475423,839,985 - 23,851,756 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475423,846,677 - 23,853,674 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RT1-DOb
226 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:40
Count of miRNA genes:37
Interacting mature miRNAs:39
Transcripts:ENSRNOT00000000526
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20460660717617956Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7175099Tcs2T cell selection QTL 2T cell selection trait (VT:0004917)expression2045040024693102Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
61474Eae1Experimental allergic encephalomyelitis QTL 13nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)2046066076691706Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126123605Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20460660717617956Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362164910078919Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036216499243559Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat

Markers in Region
D20Yum75  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2204,626,203 - 4,626,386 (-)MAPPERmRatBN7.2
Rnor_6.0204,019,542 - 4,019,724NCBIRnor6.0
Rnor_5.0206,099,088 - 6,099,270UniSTSRnor5.0
RGSC_v3.4204,760,309 - 4,760,491UniSTSRGSC3.4
Celera206,227,353 - 6,227,535UniSTS
Cytogenetic Map20p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 31 107 81 80 49 25 49 6 179 78 87 35 53 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001008846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001412194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005497296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005497297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB008110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC098547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX883043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC222912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC222913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC222914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC222915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC222916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC222928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC222929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC222930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC222931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M15561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000000526   ⟹   ENSRNOP00000000526
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl204,619,939 - 4,625,667 (-)Ensembl
Rnor_6.0 Ensembl204,020,317 - 4,026,346 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000085724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl204,619,816 - 4,625,667 (-)Ensembl
Rnor_6.0 Ensembl204,023,992 - 4,026,183 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092127
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl204,020,380 - 4,022,945 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105085   ⟹   ENSRNOP00000082639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl204,619,816 - 4,625,603 (-)Ensembl
RefSeq Acc Id: NM_001008846   ⟹   NP_001008846
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8204,621,336 - 4,627,523 (-)NCBI
mRatBN7.2204,619,418 - 4,625,607 (-)NCBI
Rnor_6.0204,020,385 - 4,025,987 (+)NCBI
Rnor_5.0206,099,866 - 6,105,845 (+)NCBI
RGSC_v3.4204,753,940 - 4,759,648 (-)RGD
Celera206,221,090 - 6,226,692 (-)RGD
Sequence:
RefSeq Acc Id: NM_001412194   ⟹   NP_001399123
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8204,621,336 - 4,627,523 (-)NCBI
mRatBN7.2204,619,418 - 4,625,607 (-)NCBI
RefSeq Acc Id: XR_005497296
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8204,621,795 - 4,627,536 (-)NCBI
mRatBN7.2204,619,599 - 4,625,626 (-)NCBI
RefSeq Acc Id: XR_005497297
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8204,621,788 - 4,627,537 (-)NCBI
mRatBN7.2204,619,599 - 4,625,627 (-)NCBI
RefSeq Acc Id: NP_001008846   ⟸   NM_001008846
- Peptide Label: isoform 1
- UniProtKB: Q6MGA2 (UniProtKB/TrEMBL),   A6JJD8 (UniProtKB/TrEMBL),   A0A023IM52 (UniProtKB/TrEMBL),   A0A023ILQ6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000000526   ⟸   ENSRNOT00000000526
Ensembl Acc Id: ENSRNOP00000082639   ⟸   ENSRNOT00000105085
RefSeq Acc Id: NP_001399123   ⟸   NM_001412194
- Peptide Label: isoform 2
- UniProtKB: A0A023IM57 (UniProtKB/TrEMBL),   A0A023ILR5 (UniProtKB/TrEMBL)
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6MGA2-F1-model_v2 AlphaFold Q6MGA2 1-272 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701327
Promoter ID:EPDNEW_R11850
Type:multiple initiation site
Name:RT1-DOb_1
Description:RT1 class II, locus DOb
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0204,020,321 - 4,020,381EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1595814 AgrOrtholog
BioCyc Gene G2FUF-4556 BioCyc
Ensembl Genes ENSRNOG00000000454 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000526.4 UniProtKB/TrEMBL
  ENSRNOT00000085724 ENTREZGENE
  ENSRNOT00000085724.2 UniProtKB/TrEMBL
  ENSRNOT00000105085.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  Class II Histocompatibility Antigen, M Beta Chain, Chain B, domain 1 UniProtKB/TrEMBL
InterPro Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/TrEMBL
  MHC/Immunoglobulin UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  MHC_II_a/b_N UniProtKB/TrEMBL
  MHC_II_b_N UniProtKB/TrEMBL
KEGG Report rno:365542 UniProtKB/TrEMBL
NCBI Gene 365542 ENTREZGENE
PANTHER HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DO BETA CHAIN UniProtKB/TrEMBL
  MHC CLASS II-RELATED UniProtKB/TrEMBL
Pfam C1-set UniProtKB/TrEMBL
  MHC_II_beta UniProtKB/TrEMBL
PhenoGen RT1-DOb PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
  IG_MHC UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000454 RatGTEx
SMART IGc1 UniProtKB/TrEMBL
  MHC_II_beta UniProtKB/TrEMBL
Superfamily-SCOP MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A0A023ILQ6 ENTREZGENE, UniProtKB/TrEMBL
  A0A023ILR5 ENTREZGENE, UniProtKB/TrEMBL
  A0A023IM52 ENTREZGENE, UniProtKB/TrEMBL
  A0A023IM57 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G9Q6_RAT UniProtKB/TrEMBL
  A6JJD8 ENTREZGENE
  F7EQQ6_RAT UniProtKB/TrEMBL
  O88189_RAT UniProtKB/TrEMBL
  Q6MGA2 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A6JJD8 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-09-14 RT1-DOb   RT1 class II, locus DOb  H2-Ob  histocompatibility 2, O region beta locus  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 H2-Ob  histocompatibility 2, O region beta locus  RT1-DOb  RT1 class II, locus DOb  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-04-12 RT1-DOb  RT1 class II, locus DOb  RT1-DOb_mapped  RT1 class II, locus DOb (mapped)  Data merged from RGD:3478 737654 APPROVED
2006-11-20 RT1-DOb_mapped  RT1 class II, locus DOb(mapped)  RT1-DOb  RT1 class II, locus DOb  Symbol set to symbol_mapped, name set to name (mapped) 1582166 APPROVED
2006-11-20 RT1-DOb  RT1 class II, locus DOb      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-02-11 RT1-DOb  RT1 class II, locus DOb      Symbol and Name status set to approved 625702 APPROVED
2002-06-10 RT1-DOb  RT1 class II, locus DOb      Symbol and Name status set to approved 70586 APPROVED