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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:obesity
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Accession:DOID:9970 term browser browse the term
Definition:An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness. (DO)
Synonyms:exact_synonym: obesity disorder
 narrow_synonym: ADCY3-RELATED CONDITION;   MONOGENIC NON-SYNDROMIC OBESITY;   MONOGENIC OBESITY;   Maternal Obesity;   NR0B2-RELATED CONDITION;   OBESITY DUE TO MELANOCORTIN 4 RECEPTOR DEFICIENCY;   OBESITY DUE TO SIM1 DEFICIENCY;   OBESITY, MILD, EARLY-ONSET;   Obesity, Late-Onset;   Obesity, autosomal dominant;   SIM1-RELATED CONDITION;   severe obesity and type II diabetes
 broad_synonym: UCP3-related condition
 related_synonym: LEANNESS;   MELANOCORTIN 4 RECEPTOR POLYMORPHISM;   OBESITY, AGE AT ONSET OF;   OBESITY, ASSOCIATION WITH;   OBESITY, EARLY-ONSET, SUSCEPTIBILITY TO;   OBESITY, RESISTANCE TO;   OBESITY, SUSCEPTIBILITY TO;   UCP3 polymorphism G/A;   obesity, variation in
 xref: EFO:0001073;   ICD10CM:E66.9;   ICD9CM:278.00;   MESH:D000079262;   MESH:D009765;   MIM:601665;   MONDO:0011122;   NCI:C159658;   NCI:C3283


show annotations for term's descendants           Sort by:
obesity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AACS acetoacetyl-CoA synthetase ISO mRNA:altered expression:thalamus, hypothalamus (rat) RGD PMID:19219059 RGD:2326191 NCBI chr14:28,109,845...28,169,261
Ensembl chr14:28,109,869...28,169,253 		JBrowse link
G ABCA1 ATP binding cassette subfamily A member 1 susceptibility
disease_progression		 ISO DNA:SNP:exon:p.R230C (rs9282541) (human)
mRNA:increased expression:liver (rat)		 RGD PMID:17287470 PMID:25612518 RGD:15045599 RGD:1601092 NCBI chr 1:246,144,277...246,278,492
Ensembl chr 1:246,144,277...246,278,492 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 ISO RGD PMID:21726512 RGD:14688050 NCBI chr15:75,402,296...75,487,092
Ensembl chr15:75,402,396...75,486,403 		JBrowse link
G ABCG5 ATP binding cassette subfamily G member 5 disease_progression ISO mRNA:increased expression:liver (rat) RGD PMID:25612518 RGD:15045599 NCBI chr 3:96,616,304...96,656,893
Ensembl chr 3:96,616,246...96,656,889 		JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 ISO RGD PMID:15331430 RGD:1601095 NCBI chr 3:96,596,975...96,616,224
Ensembl chr 3:96,596,531...96,616,229 		JBrowse link
G ACACB acetyl-CoA carboxylase beta treatment ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:left ventricle myocardium (rat)		 CTD
RGD		 PMID:20882379 PMID:33310031 RGD:329955450 NCBI chr14:41,621,574...41,739,916
Ensembl chr14:41,621,574...41,739,916 		JBrowse link
G ACADM acyl-CoA dehydrogenase medium chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr 6:137,541,481...137,575,544
Ensembl chr 6:137,541,381...137,595,108 		JBrowse link
G ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 no_association ISO protein:increased expression:liver RGD PMID:17164796 PMID:19361967 RGD:1601115 RGD:2325227 NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,703 		JBrowse link
G ACHE acetylcholinesterase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29273807 NCBI chr 3:8,732,451...8,738,274
Ensembl chr 3:8,732,441...8,738,605 		JBrowse link
G ACLY ATP citrate lyase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr12:20,796,678...20,841,301
Ensembl chr12:20,796,749...20,841,298 		JBrowse link
G ACOX1 acyl-CoA oxidase 1 treatment ISO RGD PMID:30298849 RGD:401960083 NCBI chr12:5,450,913...5,479,550
Ensembl chr12:5,439,361...5,479,546 		JBrowse link
G ACP1 acid phosphatase 1 severity ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:2373509 PMID:9198310 RGD:1625289 RGD:2313187 NCBI chr 3:132,671,408...132,684,793
Ensembl chr 3:132,667,045...132,684,674 		JBrowse link
G ACP5 acid phosphatase 5, tartrate resistant ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr 2:70,206,159...70,209,855
Ensembl chr 2:70,206,162...70,208,229 		JBrowse link
G ACSL1 acyl-CoA synthetase long chain family member 1 ISO mRNA, protein:increased expression:adipose tissue, liver
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:subcutaneous adipose tissue		 RGD
CTD		 PMID:1543733 PMID:16788709 PMID:20882379 RGD:1625735 RGD:1625737 NCBI chr15:45,866,858...45,936,327
Ensembl chr15:45,866,857...45,963,729 		JBrowse link
G ADA adenosine deaminase ISO protein:increased expression:serum RGD PMID:16501670 RGD:1624289 NCBI chr17:47,044,492...47,072,232
Ensembl chr17:47,044,497...47,072,245 		JBrowse link
G ADARB1 adenosine deaminase RNA specific B1 ISO associated with Hyperphagia RGD PMID:17567573 RGD:10450894 NCBI chr13:207,746,915...207,791,809
Ensembl chr13:207,691,174...207,791,802 		JBrowse link
G ADCY3 adenylate cyclase 3 treatment ISO ClinVar Annotator: match by term: ADCY3-related condition | ClinVar Annotator: match by term: Monogenic Non-Syndromic Obesity ClinVar
RGD		 PMID:9536098 PMID:17576681 PMID:25741868 PMID:28492532 PMID:30568259 RGD:407550184 NCBI chr 3:113,875,005...113,969,053
Ensembl chr 3:113,876,339...113,982,369 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic
associated with Pulmonary Disease, Chronic Obstructive; protein:decreased expression:plasma
associated with myocardial infarction; protein:decreased expression:plasma
associated with Diabetes Mellitus, Type 2		 CTD
RGD		 PMID:10092513 PMID:14617771 PMID:16092047 PMID:18303100 PMID:18651432 More... RGD:14975146 RGD:1599149 RGD:2313239 RGD:5686809 RGD:5686813 RGD:8695927 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646 		JBrowse link
G ADIPOR1 adiponectin receptor 1 ISO mRNA:decreased expression:lymphocyte RGD PMID:17391161 RGD:1625761 NCBI chr10:24,907,491...24,923,540
Ensembl chr10:24,907,491...24,915,686 		JBrowse link
G ADIPOR2 adiponectin receptor 2 treatment
severity		 ISO mRNA:increased expression:liver
associated with non-alcoholic fatty liver disease
mRNA:decreased expression:liver (rat)		 RGD PMID:16483885 PMID:23838384 PMID:30131158 PMID:30225267 RGD:1625763 RGD:21406435 RGD:25824942 RGD:8695926 NCBI chr 5:68,755,789...68,807,247
Ensembl chr 5:68,755,811...68,807,235 		JBrowse link
G ADM adrenomedullin ISO mRNA, protein:increased expression:adipose tissue RGD PMID:16793965 RGD:1625297 NCBI chr 2:49,229,223...49,231,521
Ensembl chr 2:49,229,223...49,231,866 		JBrowse link
G ADORA1 adenosine A1 receptor ISO protein:increased expression:visceral adipose tissue:increased density of ligand binding sites on VAT in African American women compared to Caucasian women RGD PMID:16507638 RGD:1625369 NCBI chr 9:113,835,279...113,875,899
Ensembl chr 9:113,835,921...113,872,365 		JBrowse link
G ADRA2B adrenoceptor alpha 2B ISO RGD PMID:10404816 RGD:1300265 NCBI chr 3:45,760,966...45,762,306
Ensembl chr 3:45,760,541...45,764,175 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12032746 NCBI chr14:124,400,330...124,401,739
Ensembl chr14:124,400,330...124,401,739 		JBrowse link
G ADRB2 adrenoceptor beta 2 susceptibility
no_association		 ISO DNA:polymorphisms: :p.R16G, p.Q27E
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12161655 PMID:15687340 PMID:17027833 PMID:17221209 RGD:1601119 RGD:1601122 RGD:737773 NCBI chr 2:150,032,649...150,035,591
Ensembl chr 2:150,033,579...150,040,731 		JBrowse link
G ADRB3 adrenoceptor beta 3 no_association
susceptibility		 ISO DNA:missense mutation:cds:p.W64R rs4994 (human)
ClinVar Annotator: match by term: Obesity		 RGD
ClinVar
OMIM		 PMID:7609750 PMID:7609752 PMID:8903328 PMID:8954053 PMID:9054940 More... RGD:5684409 NCBI chr15:48,468,803...48,478,370
Ensembl chr15:48,475,144...48,479,562 		JBrowse link
G AFF4 ALF transcription elongation factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25730767 NCBI chr 2:135,196,067...135,283,931
Ensembl chr 2:135,200,076...135,283,675 		JBrowse link
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 ISO RGD PMID:20068140 RGD:13838849 NCBI chr 5:23,015,777...23,035,943
Ensembl chr 5:23,017,176...23,033,517 		JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO protein:decreased expression:plasma (human) RGD PMID:22761461 PMID:23046363 RGD:7243247 RGD:7243250 NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,120...24,221,162 		JBrowse link
G AGRP agouti related neuropeptide ISO ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity, late-onset OMIM
ClinVar		 PMID:11602360 PMID:12213871 PMID:15054840 PMID:25741868 NCBI chr 6:28,132,614...28,135,594
Ensembl chr 6:28,132,615...28,134,900 		JBrowse link
G AGT angiotensinogen susceptibility ISO DNA:polymorphism: :p.M235T
DNA:polymorphism: :p.T174M		 RGD PMID:16514903 PMID:16713443 RGD:1601142 RGD:1601143 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:15793237 RGD:2313554 NCBI chr  X:95,267,709...95,272,237
Ensembl chr  X:95,269,300...95,270,388 		JBrowse link
G AHI1 Abelson helper integration site 1 ISO mRNA:increased expression:vastus lateralis RGD PMID:20045148 RGD:11537398 NCBI chr 1:28,566,279...28,760,471
Ensembl chr 1:28,566,397...28,760,467 		JBrowse link
G AHR aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27020609 PMID:30813227 PMID:31306034 NCBI chr 9:86,511,866...86,555,950
Ensembl chr 9:86,511,369...86,555,943 		JBrowse link
G AHSG alpha 2-HS glycoprotein susceptibility ISO protein:increased expression:serum RGD PMID:17011519 PMID:19228823 RGD:1625793 RGD:2313809 NCBI chr13:124,426,313...124,438,848
Ensembl chr13:124,426,308...124,438,840 		JBrowse link
G AK1 adenylate kinase 1 ISO protein:increased expression:skeletal muscle RGD PMID:15855311 RGD:1601154 NCBI chr 1:268,355,032...268,365,659
Ensembl chr 1:268,355,033...268,365,598 		JBrowse link
G AKAP1 A-kinase anchoring protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20975297 NCBI chr12:33,396,473...33,410,395
Ensembl chr12:33,396,473...33,411,440 		JBrowse link
G AKR1C1 aldo-keto reductase family 1, member C1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr10:65,580,297...65,594,998
Ensembl chr10:65,576,464...65,678,248 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism
protein:increased phosphorylation:aorta		 CTD
RGD		 PMID:19293429 PMID:23954404 RGD:408364952
G AKT2 AKT serine/threonine kinase 2 ISO protein:decreased activity:rectus abdominis (human)
protein:decreased expression:plantaris (rat)		 RGD PMID:12663464 PMID:17923673 PMID:18508911 RGD:2313320 RGD:2313406 RGD:2313409 NCBI chr 6:48,555,785...48,620,472
Ensembl chr 6:48,555,795...48,587,919 		JBrowse link
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr 7:53,748,585...53,794,777
Ensembl chr 7:53,748,653...53,794,706 		JBrowse link
G ALDH6A1 aldehyde dehydrogenase 6 family member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr 7:97,360,583...97,381,885
Ensembl chr 7:97,360,610...97,381,830 		JBrowse link
G ALMS1 ALMS1 centrosome and basal body associated protein ISO OMIM:601665 MouseDO NCBI chr 3:69,253,742...69,417,043
Ensembl chr 3:69,253,750...69,417,189 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO mRNA:increased expression:adipose tissue, fat cell RGD PMID:18780776 PMID:20978234 RGD:5509594 RGD:5509628 NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,401,810...52,414,903 		JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein ISO mRNA:increased expression:adipose tissue (mouse)
mRNA:increased expression:peripheral blood mononuclear cell (human)		 RGD PMID:17379835 PMID:19596146 RGD:2313884 RGD:2313913 NCBI chr11:7,371,328...7,438,111
Ensembl chr11:7,411,644...7,438,108 		JBrowse link
G AMH anti-Mullerian hormone ISO protein:decreased expression:serum RGD PMID:17109858 RGD:1601182 NCBI chr 2:76,415,564...76,418,315
Ensembl chr 2:76,414,427...76,418,312 		JBrowse link
G ANGPTL4 angiopoietin like 4 resistance ISO CTD Direct Evidence: therapeutic RGD
CTD		 PMID:17210919 PMID:28842503 RGD:1625353 NCBI chr 2:70,905,767...70,912,892
Ensembl chr 2:70,904,531...70,912,974 		JBrowse link
G ANGPTL6 angiopoietin like 6 ISO OMIM:601665 MouseDO NCBI chr 2:68,947,067...68,958,820
Ensembl chr 2:68,947,071...68,958,766 		JBrowse link
G APCDD1 APC down-regulated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28242765 NCBI chr 6:97,991,418...98,026,590
Ensembl chr 6:97,992,233...98,026,766 		JBrowse link
G APLN apelin ISO mRNA:increased expression:subcutaneous adipose tissue RGD PMID:17594060 RGD:1626170 NCBI chr  X:106,236,746...106,246,563
Ensembl chr  X:106,236,749...106,246,377 		JBrowse link
G APOA1 apolipoprotein A1 ISO protein:decreased expression RGD PMID:9933608 PMID:12725089 RGD:1601185 RGD:2313959 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,392...44,218,713 		JBrowse link
G APOA2 apolipoprotein A2 ISO protein:increased expression:serum RGD PMID:9002300 PMID:9933608 RGD:1601191 RGD:2313959 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,319 		JBrowse link
G APOA5 apolipoprotein A5 ISO DNA:SNP: :rs662799 (human) RGD PMID:25606423 RGD:329901774 NCBI chr 9:44,177,834...44,180,880
Ensembl chr 9:44,178,606...44,180,885 		JBrowse link
G APOB apolipoprotein B ISO associated with Insulin Resistance;protein:increased expression:plasma RGD PMID:16752182 PMID:19592617 RGD:1601202 RGD:2313974 NCBI chr 3:117,250,096...117,316,200
Ensembl chr 3:117,250,096...117,316,200 		JBrowse link
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 ISO mRNA:increased expression:liver RGD PMID:8781289 RGD:1626278 NCBI chr 5:62,811,819...62,820,532
Ensembl chr 5:62,810,879...62,820,173 		JBrowse link
G APOC2 apolipoprotein C2 ISO protein:increased expression:serum RGD PMID:9002300 RGD:1601191 NCBI chr 6:51,404,219...51,406,302 JBrowse link
G APOC3 apolipoprotein C3 ISO protein:increased expression:serum RGD PMID:9002300 RGD:1601191 NCBI chr 9:44,211,171...44,213,538
Ensembl chr 9:44,211,194...44,213,533 		JBrowse link
G APOD apolipoprotein D ISO DNA:polymorphism RGD PMID:7913935 RGD:2311179 NCBI chr13:132,514,546...132,562,594
Ensembl chr13:132,514,949...132,562,599 		JBrowse link
G APOE apolipoprotein E ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:9002300 PMID:17192461 PMID:20975297 RGD:1601191 RGD:1601230 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G APP amyloid beta precursor protein treatment ISO mRNA,protein:increased expression:adipocyte,plasma: RGD PMID:19672057 RGD:10054260 NCBI chr13:189,434,854...189,716,120
Ensembl chr13:189,435,094...189,716,056 		JBrowse link
G AQP7 aquaporin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16325777 NCBI chr10:33,098,746...33,130,245 JBrowse link
G AR androgen receptor susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:repeat: :CAG
DNA:repeats: :GGN, CAG
OMIM:601665		 RGD
MouseDO		 PMID:12532157 PMID:18805913 RGD:1601246 RGD:2306771 NCBI chr  X:53,609,113...53,806,778
Ensembl chr  X:53,609,176...53,800,677 		JBrowse link
G ARL13B ADP ribosylation factor like GTPase 13B ISO protein:decreased expression:hypothalamus, cilium (mouse) RGD PMID:22581473 RGD:11553936 NCBI chr13:165,829,772...165,910,959
Ensembl chr13:165,828,059...165,910,961 		JBrowse link
G ASIP agouti signaling protein susceptibility ISO DNA, mRNA:deletion, insertions, increased expression: multiple organs
OMIM:601665
CTD Direct Evidence: marker/mechanism		 RGD
MouseDO
CTD		 PMID:1473152 PMID:7987393 PMID:8146154 PMID:25447408 PMID:25448685 More... RGD:1625724 NCBI chr17:37,542,615...37,718,787
Ensembl chr17:37,545,474...37,718,779 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 susceptibility ISO RGD PMID:16286513 RGD:1601250 NCBI chr 4:90,341,316...90,371,040
Ensembl chr 4:90,341,322...90,370,996 		JBrowse link
G ATP4B ATPase H+/K+ transporting subunit beta treatment ISO RGD PMID:25822172 RGD:14696745 NCBI chr11:78,780,013...78,785,143
Ensembl chr11:78,780,013...78,785,116 		JBrowse link
G ATP5F1B ATP synthase F1 subunit beta treatment ISO RGD PMID:26880535 RGD:13782133 NCBI chr 5:21,984,750...21,992,393
Ensembl chr 5:21,984,580...21,992,407 		JBrowse link
G ATP5F1C ATP synthase F1 subunit gamma ISO RGD PMID:19549744 RGD:14696798 NCBI chr10:63,584,288...63,599,537
Ensembl chr10:63,583,695...63,599,453 		JBrowse link
G ATP5F1D ATP synthase F1 subunit delta treatment ISO RGD PMID:27874268 RGD:13792665 NCBI chr 2:77,216,430...77,219,301
Ensembl chr 2:77,216,436...77,222,632 		JBrowse link
G ATP5MC2 ATP synthase membrane subunit c locus 2 ISO RGD PMID:26709097 RGD:11535661 NCBI chr 5:18,871,025...18,879,933
Ensembl chr 5:18,871,026...18,879,609 		JBrowse link
G ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr 6:164,830,623...164,858,741
Ensembl chr 6:164,830,749...164,862,218 		JBrowse link
G ATRN attractin ISO RGD PMID:10086355 RGD:734623 NCBI chr17:32,054,240...32,239,576
Ensembl chr17:32,054,249...32,239,519 		JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding ISO mRNA:decreased expression:fat pad
protein:decreased expression:plasma
mRNA, protein:decreased expression:fat pad, liver,plasma
associated with colorectal cancer; protein:decreased expression:subcutaneous white adipose tissue		 RGD PMID:19934249 PMID:21136593 PMID:29755407 RGD:153350147 RGD:153350156 RGD:153350157 NCBI chr 3:7,867,521...7,874,857 JBrowse link
G B2M beta-2-microglobulin ISO protein:increased expression:urine RGD PMID:15517379 RGD:1601309 NCBI chr 1:126,837,721...126,844,043
Ensembl chr 1:126,835,143...126,981,582 		JBrowse link
G BAD BCL2 associated agonist of cell death ISO protein:increased expression:heart left ventricle RGD PMID:18070754 RGD:2292682 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863 		JBrowse link
G BAMBI BMP and activin membrane bound inhibitor ISO mRNA:decreased expression:adipose tissue RGD PMID:22187378 RGD:14390162 NCBI chr10:40,053,368...40,058,590
Ensembl chr10:40,053,355...40,060,319 		JBrowse link
G BBS1 Bardet-Biedl syndrome 1 no_association ISO DNA:mutation: :p.M390R (human)
OMIM:601665		 RGD
MouseDO		 PMID:14993910 PMID:33722691 RGD:1601314 RGD:243065268 NCBI chr 2:5,886,989...5,906,468
Ensembl chr 2:5,886,990...5,906,388 		JBrowse link
G BBS2 Bardet-Biedl syndrome 2 susceptibility ISO DNA:SNPs RGD PMID:17003356 RGD:1601311 NCBI chr 6:18,542,383...18,575,338
Ensembl chr 6:18,542,386...18,575,514 		JBrowse link
G BBS4 Bardet-Biedl syndrome 4 onset ISO DNA:SNPs
OMIM:601665		 RGD
MouseDO		 PMID:17003356 RGD:1601311 NCBI chr 7:60,631,913...60,693,359
Ensembl chr 7:60,631,914...60,693,334 		JBrowse link
G BCHE butyrylcholinesterase ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:18452903 PMID:23000450 PMID:23073171 PMID:27163854 NCBI chr13:104,946,732...105,007,568 JBrowse link
G BCL2 BCL2 apoptosis regulator ISO mRNA, protein:decreased expression:heart left ventricle RGD PMID:18202171 RGD:2293027 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G BDKRB1 bradykinin receptor B1 ISO ob/ob mice mRNA:decreased expression:brown adipose tissue, heart mRNA:increased expression:white adipose tissue, hypothalamus RGD PMID:17184856 RGD:1625733 NCBI chr 7:117,491,350...117,492,410
Ensembl chr 7:117,491,350...117,492,410 		JBrowse link
G BDNF brain derived neurotrophic factor ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:11840487 PMID:25741868 PMID:28492532 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,624,048...32,679,765 		JBrowse link
G BNIP3 BCL2 interacting protein 3 ISO RGD PMID:18070754 RGD:2292682 NCBI chr14:140,362,123...140,371,951
Ensembl chr14:140,362,127...140,371,907 		JBrowse link
G BRD2 bromodomain containing 2 ISO RGD PMID:19883376 RGD:9586446 NCBI chr 7:25,096,579...25,162,591
Ensembl chr 7:25,150,564...25,162,584 		JBrowse link
G BRS3 bombesin receptor subtype 3 ISO RGD PMID:9367152 RGD:734661 NCBI chr  X:111,615,695...111,620,124
Ensembl chr  X:111,615,564...111,620,124 		JBrowse link
G C3 complement C3 treatment ISO RGD PMID:23118029 RGD:7411625 NCBI chr 2:72,431,470...72,471,622
Ensembl chr 2:72,431,212...72,472,228 		JBrowse link
G C5AR1 complement C5a receptor 1 treatment ISO RGD PMID:23118029 RGD:7411625 NCBI chr 6:53,097,162...53,111,563
Ensembl chr 6:53,097,142...53,111,565 		JBrowse link
G CA3 carbonic anhydrase 3 ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:adipocyte		 CTD
RGD		 PMID:8476041 PMID:20882379 RGD:408426009 NCBI chr 4:51,227,485...51,237,861
Ensembl chr 4:51,227,485...51,237,844 		JBrowse link
G CADM2 cell adhesion molecule 2 ISO DNA:SNP: :rs13078807 (human) RGD PMID:31341224 RGD:15092077 NCBI chr13:169,681,947...170,753,114
Ensembl chr13:169,688,958...170,014,005 		JBrowse link
G CANX calnexin ISO protein:increased expression:subcutaneous adipose tissue RGD PMID:18567819 RGD:2314284 NCBI chr 2:78,879,031...78,915,828
Ensembl chr 2:78,879,033...78,915,827 		JBrowse link
G CAPN10 calpain 10 ISO DNA:SNPs RGD PMID:16752174 RGD:1625047 NCBI chr15:139,557,643...139,568,764
Ensembl chr15:139,557,469...139,568,767 		JBrowse link
G CARTPT CART prepropeptide no_association
susceptibility		 ISO DNA:deletion, substitution: :1457delA, 1475A>G (human)
DNA:polymorphism:3' utr (human)
ClinVar Annotator: match by term: Obesity		 RGD
ClinVar
OMIM		 PMID:10574510 PMID:10805512 PMID:11522684 PMID:15326462 PMID:25741868 RGD:2313633 RGD:2313634 NCBI chr16:48,043,558...48,045,592
Ensembl chr16:48,043,492...48,045,592 		JBrowse link
G CASP1 caspase 1, apoptosis-related cysteine peptidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22325453 NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328 		JBrowse link
G CAST calpastatin ISO ClinVar Annotator: match by term: Body mass index quantitative trait locus 12 | ClinVar Annotator: match by term: Monogenic Non-Syndromic Obesity | ClinVar Annotator: match by term: Obesity due to SIM1 deficiency ClinVar PMID:18604207 PMID:22210313 PMID:23383060 PMID:25741868 PMID:28492532 NCBI chr 2:103,255,738...103,378,623
Ensembl chr 2:103,255,750...103,378,623 		JBrowse link
G CAV1 caveolin 1 ISO RGD PMID:22492718 RGD:6784520 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465 		JBrowse link
G CAV2 caveolin 2 ISO RGD PMID:22492718 RGD:6784520 NCBI chr18:29,699,012...29,707,277
Ensembl chr18:29,699,020...29,707,277 		JBrowse link
G CCKAR cholecystokinin A receptor ISO DNA:deletion RGD PMID:9192855 PMID:9530226 RGD:7257724 RGD:734711 NCBI chr 8:20,187,324...20,200,273
Ensembl chr 8:20,188,830...20,199,344 		JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 ISO protein, mRNA:increased expression:plasma, fat
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:17803693 PMID:18469848 PMID:29035695 RGD:2306993 RGD:2307038 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 ISO RGD PMID:21862610 RGD:5683906 NCBI chr12:39,479,190...39,480,511
Ensembl chr12:39,478,882...39,481,082 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased expression:serum RGD PMID:18469848 RGD:2307038 NCBI chr12:39,652,731...39,659,121
Ensembl chr12:39,648,598...39,659,118 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO mRNA:increased expression:adipose tissue RGD PMID:18492752 RGD:6483834 NCBI chr13:29,251,950...29,286,470
Ensembl chr13:29,285,012...29,286,467 		JBrowse link
G CD163 CD163 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:29035695 NCBI chr 5:63,300,200...63,334,497
Ensembl chr 5:63,300,231...63,334,498 		JBrowse link
G CD36 CD36 molecule ISO mRNA, protein:increased expression:liver, gastrocnemius
protein:increased expression:skeletal muscle, T-tubule		 RGD PMID:20435456 PMID:22615812 PMID:23743348 PMID:25477422 RGD:11041118 RGD:11041132 RGD:6893497 RGD:6893542 NCBI chr 9:99,685,748...99,782,296
Ensembl chr 9:99,605,181...99,782,105 		JBrowse link
G CD40 CD40 molecule treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21670556 PMID:29035695 RGD:7248753 NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528 		JBrowse link
G CD40LG CD40 ligand ISO protein:increased expression:serum RGD PMID:20660932 PMID:21817098 RGD:5490592 RGD:5490970 NCBI chr  X:111,778,666...111,788,901
Ensembl chr  X:111,778,493...111,789,709 		JBrowse link
G CD68 CD68 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:29035695 NCBI chr12:52,874,754...52,877,256
Ensembl chr12:52,874,785...52,877,695 		JBrowse link
G CDK4 cyclin dependent kinase 4 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:intron:IVS4-40G>A (human) RGD PMID:19634152 RGD:2314609 NCBI chr 5:23,039,206...23,041,959
Ensembl chr 5:23,038,891...23,042,061 		JBrowse link
G CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 ISO ClinVar Annotator: match by term: Obesity ClinVar NCBI chr 7:15,910,645...16,569,643
Ensembl chr 7:15,910,666...16,626,276 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO protein:decreased expression:liver RGD PMID:23357529 RGD:10045356 NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO RGD PMID:22194422 RGD:8552660 NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854 		JBrowse link
G CDO1 cysteine dioxygenase type 1 ISO RGD PMID:16627576 RGD:2301355 NCBI chr 2:119,927,768...119,940,690
Ensembl chr 2:119,927,772...119,940,665 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:28242765 NCBI chr 6:43,083,200...43,085,884
Ensembl chr 6:43,083,207...43,085,836 		JBrowse link
G CENPO centromere protein O ISO ClinVar Annotator: match by term: ADCY3-related condition ClinVar PMID:9536098 PMID:17576681 PMID:25741868 PMID:28492532 NCBI chr 3:113,968,735...113,979,201
Ensembl chr 3:113,968,902...113,979,148 		JBrowse link
G CFD complement factor D ISO mRNA, protein:decreased expression:adipocyte, serum RGD PMID:2197880 PMID:14564690 RGD:1624324 RGD:1624327 NCBI chr 2:77,509,792...77,511,988
Ensembl chr 2:77,509,795...77,511,974 		JBrowse link
G CIDEA cell death inducing DFFA like effector a ISO protein:amino acid substitution:V115F
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16186410 PMID:20975297 RGD:1625390 NCBI chr 6:97,253,074...97,268,355
Ensembl chr 6:97,253,074...97,267,405 		JBrowse link
G CNR1 cannabinoid receptor 1 no_association ISO DNA:polymorphism: :1256C>A, 1419+1G>C (human)
DNA:polymorphism:exon:3813A>G (human)
CTD Direct Evidence: marker/mechanism
DNA, mRNA:hypermethylation, increased expression:promoter, hypothalamus
DNA:hypermethylation:promoter, peripheral blood mononuclear cell		 RGD
CTD		 PMID:17292652 PMID:17405839 PMID:18722357 PMID:19325539 PMID:19530697 More... RGD:1626325 RGD:1626326 RGD:2314629 RGD:2314630 RGD:401827956 NCBI chr 1:56,466,022...56,493,275
Ensembl chr 1:56,467,835...56,492,602 		JBrowse link
G CNTF ciliary neurotrophic factor no_association ISO DNA:point mutation:intron:G>A RGD PMID:12404108 PMID:14747836 RGD:1626113 RGD:1626114 NCBI chr 2:12,492,777...12,495,401
Ensembl chr 2:12,493,169...12,496,159 		JBrowse link
G COL1A1 collagen type I alpha 1 chain ISO mRNA:increased expression:kidney (rat) RGD PMID:28746409 RGD:401965413 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G COL3A1 collagen type III alpha 1 chain ISO mRNA:increased expression:kidney (rat) RGD PMID:28746409 RGD:401965413 NCBI chr15:93,556,914...93,595,678
Ensembl chr15:93,526,603...93,596,363 		JBrowse link
G COL4A1 collagen type IV alpha 1 chain ISO mRNA:increased expression:kidney (rat) RGD PMID:28746409 RGD:401965413 NCBI chr11:76,858,332...76,997,409
Ensembl chr11:76,858,356...76,997,322 		JBrowse link
G COMT catechol-O-methyltransferase susceptibility ISO DNA:polymorphism:exon RGD PMID:17497175 RGD:2289713 NCBI chr14:51,384,729...51,403,997
Ensembl chr14:51,385,738...51,403,998 		JBrowse link
G COX7C cytochrome c oxidase subunit 7C ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr 2:94,345,436...94,347,709
Ensembl chr 2:94,345,447...94,352,651 		JBrowse link
G CPB2 carboxypeptidase B2 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression, increased activity:plasma
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:11836301 PMID:16959692 RGD:2313645 NCBI chr11:21,234,447...21,298,250
Ensembl chr11:21,234,447...21,298,241 		JBrowse link
G CPE carboxypeptidase E no_association ISO DNA:transition:CDS:729T>C, amino acid S202P; decreased activity results in decrease in processing of proinsulin
CTD Direct Evidence: marker/mechanism
no association between obesity or diabetes and three SNPs (-53G>T, -144G>A, 219G>A) in Japanese patients
OMIM:601665
DNA:SNP:intron (rs1946816, rs4481204) (human)		 RGD
CTD
MouseDO		 PMID:7663508 PMID:9662053 PMID:15358678 PMID:23434795 PMID:23900445 RGD:1626181 RGD:1626184 RGD:405650675 NCBI chr 8:43,568,744...43,695,475
Ensembl chr 8:43,565,054...43,696,268 		JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 ISO RGD PMID:15481768 RGD:2303517 NCBI chr15:113,210,038...113,339,086
Ensembl chr15:113,150,157...113,339,078 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A treatment ISO mRNA:decreased expression:liver
mRNA:decreased expression:left ventricle myocardium (rat)		 RGD PMID:16751799 PMID:33310031 RGD:2311345 RGD:329955450 NCBI chr 2:4,250,642...4,293,914
Ensembl chr 2:4,233,099...4,293,911 		JBrowse link
G CRH corticotropin releasing hormone ISO RGD PMID:11564446 RGD:5508830 NCBI chr 4:68,481,696...68,486,122
Ensembl chr 4:68,484,053...68,486,121 		JBrowse link
G CRHBP corticotropin releasing hormone binding protein ISO mRNA:decreased expression:anterior pituitary gland (rat) RGD PMID:10600923 RGD:5508840 NCBI chr 2:85,814,399...85,830,598
Ensembl chr 2:85,816,816...85,831,179 		JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO DNA:SNP:CDS:861C>T (human) RGD PMID:14724656 RGD:1626226 NCBI chr12:17,251,361...17,306,308
Ensembl chr12:17,252,020...17,306,285 		JBrowse link
G CRP C-reactive protein, pentraxin-related disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
mRNA:increased expression:liver (rat)		 CTD
RGD		 PMID:20660932 PMID:24042701 PMID:25612518 RGD:15045599 RGD:5490970 NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,793,350...90,805,218 		JBrowse link
G CS citrate synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr 5:21,669,778...21,700,737
Ensembl chr 5:21,666,585...21,700,711 		JBrowse link
G CST3 cystatin C ISO protein:increased expression:serum (human)
protein:increased expression:plasma (rat)		 RGD PMID:18374694 PMID:18946178 RGD:2314297 RGD:2314346 NCBI chr17:30,471,056...30,474,486
Ensembl chr17:30,470,855...30,474,590 		JBrowse link
G CTF1 cardiotrophin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21803294 NCBI chr 3:17,539,927...17,545,250
Ensembl chr 3:17,539,941...17,544,396 		JBrowse link
G CTSC cathepsin C ISO RGD PMID:3705543 RGD:1599645 NCBI chr 9:21,726,628...21,761,796
Ensembl chr 9:21,722,036...21,761,516 		JBrowse link
G CTSS cathepsin S ISO CTD Direct Evidence: marker/mechanism CTD PMID:21156398 NCBI chr 4:98,415,273...98,442,952
Ensembl chr 4:98,417,883...98,442,950 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO DNA:SNP: :p.T280M (human) RGD PMID:20523302 RGD:4891903 NCBI chr13:23,944,386...23,957,567
Ensembl chr13:23,944,369...23,957,486 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 ISO RGD PMID:25016030 RGD:13673852 NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,232 		JBrowse link
G CYB5A cytochrome b5 type A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr 1:149,737,584...149,773,222
Ensembl chr 1:149,737,571...149,773,219 		JBrowse link
G CYCS cytochrome c, somatic ISO CTD Direct Evidence: marker/mechanism CTD PMID:16317704 NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO CTD Direct Evidence: therapeutic CTD PMID:27036855 NCBI chr 3:102,195,743...102,205,687
Ensembl chr 3:102,195,741...102,205,683 		JBrowse link
G CYP26B1 cytochrome P450 family 26 subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr 3:70,573,551...70,593,416
Ensembl chr 3:70,572,197...70,593,408 		JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphisms:promoter, intron:g.-1260C>A, g.2838T>C (human) RGD PMID:17223345 RGD:2307312 NCBI chr 5:23,053,129...23,058,865
Ensembl chr 5:23,053,892...23,058,470 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO CTD Direct Evidence: marker/mechanism
protein:increased activity:liver,fat		 CTD
RGD		 PMID:17049493 PMID:23954404 RGD:1626307 NCBI chr14:141,690,737...141,703,078
Ensembl chr14:141,690,426...141,736,817 		JBrowse link
G CYP2R1 cytochrome P450 family 2 subfamily R member 1 ISO associated with hypertension:DNA:SNP:CDS: rs12794714 (human) RGD PMID:34906413 RGD:401900724 NCBI chr 2:44,375,432...44,394,122
Ensembl chr 2:44,375,520...44,396,334 		JBrowse link
G DCN decorin ISO RGD PMID:17244723 RGD:1600551 NCBI chr 5:91,678,601...91,713,925
Ensembl chr 5:91,682,658...91,714,235 		JBrowse link
G DCXR dicarbonyl and L-xylulose reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr12:978,131...980,042
Ensembl chr12:978,139...982,259 		JBrowse link
G DDHD2 DDHD domain containing 2 ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:23176823 PMID:24337409 PMID:24517879 PMID:25417924 PMID:25741868 More... NCBI chr15:48,239,932...48,292,413
Ensembl chr15:48,252,338...48,292,181 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26655953 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829 		JBrowse link
G DEAF1 DEAF1 transcription factor ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:25741868 PMID:28492532 NCBI chr 2:404,514...427,584
Ensembl chr 2:404,533...427,542 		JBrowse link
G DEFB1 defensin beta 1 ISO mRNA:decreased expression:kidney RGD PMID:11340353 RGD:4892260
G DGAT1 diacylglycerol O-acyltransferase 1 no_association
treatment		 ISO DNA:polymorphism:C97T RGD PMID:10802663 PMID:14569040 PMID:18183944 RGD:10401058 RGD:1625597 RGD:734536 NCBI chr 4:452,890...463,665
Ensembl chr 4:452,662...466,684 		JBrowse link
G DIO2 iodothyronine deiodinase 2 no_association ISO protein:substitution:Thr92Ala RGD PMID:17077128 RGD:1626439 NCBI chr 7:103,096,414...103,110,749
Ensembl chr 7:103,096,433...103,323,258 		JBrowse link
G DIP2C disco interacting protein 2 homolog C ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:25741868 NCBI chr10:68,770,149...69,141,876
Ensembl chr10:68,770,164...69,141,871 		JBrowse link
G DIXDC1 DIX domain containing 1 ISO ClinVar Annotator: match by term: Obesity ClinVar NCBI chr 9:39,666,454...39,734,909 JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:24614070 PMID:25741868 PMID:28492532 NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087 		JBrowse link
G DPYD dihydropyrimidine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr 4:119,931,471...120,712,461
Ensembl chr 4:119,931,414...120,712,459 		JBrowse link
G DRD1 dopamine receptor D1 treatment ISO protein:increased serine phosphorylation:renal proximal tubule, membrane (rat) RGD PMID:15983225 PMID:17191082 RGD:7248449 RGD:7248552 NCBI chr16:49,189,555...49,193,722
Ensembl chr16:49,189,602...49,191,976 		JBrowse link
G DRD2 dopamine receptor D2 ISO mRNA:decreased expression:ventral tegmental area (rat)
DNA:polymorphism
DNA:polymorphisms, haplotype:enhancer, promoter, intron:multiple		 RGD PMID:15939106 PMID:17108814 PMID:18477764 RGD:1600904 RGD:1600905 RGD:2311581 NCBI chr 9:41,068,618...41,135,262
Ensembl chr 9:41,068,779...41,133,599 		JBrowse link
G DRD4 dopamine receptor D4 ISO protein:decreased expression:kidney (rat) RGD PMID:20810614 RGD:7248616 NCBI chr 2:398,766...401,539
Ensembl chr 2:398,766...402,433 		JBrowse link
G DUSP1 dual specificity phosphatase 1 susceptibility ISO RGD PMID:16814733 RGD:2298673 NCBI chr16:51,457,924...51,461,095
Ensembl chr16:51,458,020...51,461,086 		JBrowse link
G ECH1 enoyl-CoA hydratase 1 treatment ISO RGD PMID:31961704 RGD:21408561 NCBI chr 6:47,627,056...47,638,961
Ensembl chr 6:47,627,062...47,639,291 		JBrowse link
G ECHS1 enoyl-CoA hydratase, short chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr14:141,340,320...141,348,870
Ensembl chr14:141,339,364...141,348,994 		JBrowse link
G EDN1 endothelin 1 ISO DNA:polymorphism:exon:p.K198N (human) RGD PMID:17444275 RGD:1625065 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
G EFNB1 ephrin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24098442 NCBI chr  X:54,947,339...54,961,403
Ensembl chr  X:54,948,342...54,973,629 		JBrowse link
G EGFR epidermal growth factor receptor ISO protein:decreased phosphorylation:liver (mouse) RGD PMID:3624263 RGD:5131534 NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589 		JBrowse link
G EHD1 EH domain containing 1 ISO RGD PMID:21365757 RGD:8661255 NCBI chr 2:7,299,295...7,321,580
Ensembl chr 2:7,298,208...7,321,576 		JBrowse link
G ELOVL6 ELOVL fatty acid elongase 6 ISO mRNA,protein:increased expression:liver: RGD PMID:31988048 RGD:21403676 NCBI chr 8:112,038,670...112,190,079
Ensembl chr 8:112,027,054...112,191,274 		JBrowse link
G EMC1 ER membrane protein complex subunit 1 ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:26572623 PMID:26942288 PMID:28492532 PMID:29271071 NCBI chr 6:77,723,374...77,747,780
Ensembl chr 6:77,718,849...77,747,771 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 susceptibility ISO ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity disorder ClinVar
OMIM		 PMID:9662402 PMID:10453738 PMID:10480624 PMID:11739459 PMID:11771660 More... NCBI chr 1:31,724,290...31,796,594
Ensembl chr 1:31,722,721...31,796,595 		JBrowse link
G ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29273807 NCBI chr17:30,908,747...30,930,774
Ensembl chr17:30,908,252...30,934,083 		JBrowse link
G EP300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26441656 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760 		JBrowse link
G ESR1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:11095962 PMID:20667977 PMID:22230815 RGD:8553065 RGD:8553199 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363 		JBrowse link
G ESR2 estrogen receptor 2 ISO RGD PMID:22230815 RGD:8553199 NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,829,560...193,906,565 		JBrowse link
G ESRRA estrogen related receptor alpha no_association ISO RGD PMID:16755280 RGD:1625637 NCBI chr 2:7,803,504...7,812,868
Ensembl chr 2:7,803,510...7,813,098 		JBrowse link
G ETFDH electron transfer flavoprotein dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr 8:47,608,499...47,655,889
Ensembl chr 8:47,608,772...47,657,436 		JBrowse link
G F2 coagulation factor II, thrombin ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:21210148 PMID:22841818 PMID:23628972 RGD:5147773 RGD:7387310 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F7 coagulation factor VII ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased activity:plasma (human) RGD PMID:9258277 PMID:14513073 PMID:16739871 PMID:19329212 RGD:1625710 RGD:2312379 RGD:2312395 RGD:2312404 NCBI chr11:78,512,389...78,518,668
Ensembl chr11:78,512,137...78,518,668 		JBrowse link
G FAAH fatty acid amide hydrolase ISO DNA:polymorphism
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:15809662 PMID:19103437 PMID:20716455 RGD:1625726 NCBI chr 6:165,060,279...165,079,340
Ensembl chr 6:165,060,285...165,079,767 		JBrowse link
G FABP1 fatty acid binding protein 1 ISO Western diet-induced obesity; DNA:mutation::Fabp1 knockout mice RGD PMID:17058218 RGD:1626440 NCBI chr 3:57,850,511...57,854,966
Ensembl chr 3:57,850,499...57,854,956 		JBrowse link
G FABP2 fatty acid binding protein 2 onset
no_association		 ISO Early onset of obesity and resistance to reducing visceral white adipose tissue; DNA:polymorphism:CDS:amino acid A54T, in Japanese women with a BMI > 25
DNA:polymorphism:CDS:amino acid A54T, in Chilean Aymara and Mapuche ethnic groups
DNA:polymorphism:CDS:p.A54T (human)		 RGD PMID:14981227 PMID:15620432 PMID:17211557 RGD:1578458 RGD:1626400 RGD:1626407 NCBI chr 8:104,464,342...104,468,059
Ensembl chr 8:104,464,342...104,470,480 		JBrowse link
G FABP3 fatty acid binding protein 3 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA:decreased expression:skeletal muscle RGD PMID:17515913 RGD:2307328 NCBI chr 6:87,943,003...87,950,708
Ensembl chr 6:87,942,790...87,951,610 		JBrowse link
G FABP4 fatty acid binding protein 4 ISO RGD PMID:8910278 RGD:737747 NCBI chr 4:55,096,400...55,101,209
Ensembl chr 4:55,096,404...55,101,896 		JBrowse link
G FADD Fas associated via death domain ISO protein:increased expression:heart left ventricle RGD PMID:18202171 RGD:2293027 NCBI chr 2:3,191,718...3,194,820
Ensembl chr 2:3,185,675...3,194,818 		JBrowse link
G FADS1 fatty acid desaturase 1 ISO protein:decreased expression:microsomes, liver RGD PMID:8446010 RGD:1625421 NCBI chr 2:9,735,425...9,747,405
Ensembl chr 2:9,735,322...9,750,506 		JBrowse link
G FANCA FA complementation group A ISO RGD PMID:22482891 RGD:11046266 NCBI chr 6:253,207...300,159
Ensembl chr 6:253,207...300,152 		JBrowse link
G FANCC FA complementation group C ISO RGD PMID:22482891 RGD:11046266 NCBI chr10:26,796,546...27,055,271
Ensembl chr10:26,796,572...27,061,801 		JBrowse link
G FASN fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr12:922,405...937,560
Ensembl chr12:920,509...937,561 		JBrowse link
G FBXO11 F-box protein 11 ISO ClinVar Annotator: match by term: Obesity ClinVar NCBI chr 3:92,696,402...92,792,623
Ensembl chr 3:92,696,441...92,792,616 		JBrowse link
G FGD4 FYVE, RhoGEF and PH domain containing 4 ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:26825290 PMID:27328748 PMID:28492532 NCBI chr 5:41,571,054...41,636,058
Ensembl chr 5:41,570,282...41,636,028 		JBrowse link
G FGF21 fibroblast growth factor 21 ISO CTD Direct Evidence: therapeutic CTD PMID:24184811 PMID:26797127 NCBI chr 6:54,082,653...54,084,532
Ensembl chr 6:54,080,739...54,084,601 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO mRNA:increased expression:adipose tissue:
mRNA:increased expression:hypothalamus:		 RGD PMID:21430024 RGD:10402094 NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,724 		JBrowse link
G FGG fibrinogen gamma chain ISO protein:decreased expression:plasma RGD PMID:22134356 RGD:11352709 NCBI chr 8:74,553,040...74,562,151
Ensembl chr 8:74,553,105...74,563,688 		JBrowse link
G FGGY FGGY carbohydrate kinase domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:29220483 NCBI chr 6:152,754,923...153,213,179
Ensembl chr 6:152,754,924...153,213,127 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:27071101 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554 		JBrowse link
G FOXA2 forkhead box A2 ISO RGD PMID:12865419 RGD:1627574 NCBI chr17:29,997,397...30,001,704
Ensembl chr17:29,997,401...30,001,707 		JBrowse link
G FOXC2 forkhead box C2 ISO DNA:polymorphism:5'ut:-512C>T(human) RGD PMID:15601967 RGD:1601218 NCBI chr 6:2,552,141...2,555,041
Ensembl chr 6:2,552,862...2,554,367 		JBrowse link
G FOXO3 forkhead box O3 ISO protein:increased expression:myocardium:
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16467659 PMID:23954404 RGD:10402201 NCBI chr 1:74,626,673...74,760,323
Ensembl chr 1:74,628,218...74,760,325 		JBrowse link
G FTL ferritin light chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr 6:54,231,121...54,232,756
Ensembl chr 6:54,231,172...54,232,750 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase severity ISO DNA:SNPs: :rs9939609, rs1421085, rs17817449 (human)
DNA:SNP:intron:rs9939609 (human)
mRNA, protein:increased expression:liver
mRNA:increased expression:pancreas
DNA:SNP:intron:rs17817449 (human)
DNA:SNP: :rs3751812 (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs9939609 (human)		 RGD
CTD		 PMID:17496892 PMID:19079260 PMID:19079261 PMID:19151714 PMID:19918250 More... RGD:329812007 RGD:329812010 RGD:329812016 RGD:329812040 RGD:329845887 RGD:329901774 RGD:329951013 RGD:329951016 NCBI chr 6:31,177,112...31,564,674
Ensembl chr 6:31,174,569...31,564,718 		JBrowse link
G FXN frataxin ISO DNA:deletion:exon (mouse) RGD PMID:17404227 RGD:2307045 NCBI chr 1:222,412,485...222,433,224
Ensembl chr 1:222,412,509...222,434,702 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase ISO mRNA, protein:increased expression:white fat
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:liver		 RGD PMID:15923630 PMID:19230846 RGD:2307340 RGD:2307347 NCBI chr  X:125,029,147...125,041,040
Ensembl chr  X:125,029,150...125,041,040 		JBrowse link
G GABRA6 gamma-aminobutyric acid type A receptor subunit alpha6 ISO DNA:polymorphism:3' utr:1519T>C, abdominal obesity and hypercortisolism RGD PMID:12080446 RGD:1626491 NCBI chr16:61,855,698...61,872,503
Ensembl chr16:61,855,468...61,872,279 		JBrowse link
G GAL galanin and GMAP prepropeptide no_association ISO protein:increased expression:plasma RGD PMID:11220530 PMID:15930442 RGD:1624334 RGD:1625748 NCBI chr 2:4,351,113...4,357,167
Ensembl chr 2:4,351,113...4,356,647 		JBrowse link
G GALP galanin like peptide ISO mRNA:decreased expression:arcuate nucleus RGD PMID:15256810 RGD:2313739 NCBI chr 6:60,485,612...60,493,591
Ensembl chr 6:60,485,649...60,493,584 		JBrowse link
G GALR1 galanin receptor 1 no_association ISO RGD PMID:15930442 RGD:1625748 NCBI chr 1:147,442,977...147,466,731
Ensembl chr 1:147,443,821...147,463,542 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase treatment ISO RGD PMID:27987997 RGD:13792668 NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,679...64,133,991 		JBrowse link
G GAS7 growth arrest specific 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19270708 NCBI chr12:54,752,436...54,974,535
Ensembl chr12:54,752,507...54,973,515 		JBrowse link
G GCG glucagon ISO CTD Direct Evidence: therapeutic CTD PMID:20065960 NCBI chr15:68,800,557...68,810,268
Ensembl chr15:68,800,560...68,810,242 		JBrowse link
G GCKR glucokinase regulator no_association ISO DNA:mutations:CDS:no association with mutations P446L, R590Y, R227X or R518Q in obese French patients despite localization of gene within a QTL for obesity-related phenotypes RGD PMID:12739015 RGD:1626607 NCBI chr 3:111,649,557...111,683,539
Ensembl chr 3:111,649,539...111,676,772 		JBrowse link
G GFPT1 glutamine--fructose-6-phosphate transaminase 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11118009 PMID:20882379 RGD:1625423 NCBI chr 3:73,028,750...73,086,191
Ensembl chr 3:73,028,804...73,085,319 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide susceptibility ISO ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity, age at onset of ClinVar
OMIM		 PMID:11502844 PMID:12050239 PMID:12161552 PMID:16204371 PMID:25741868 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917 		JBrowse link
G GHSR growth hormone secretagogue receptor ISO DNA:point mutation:exon:F279L RGD PMID:16511600 RGD:1625270 NCBI chr13:110,981,465...111,006,149
Ensembl chr13:110,983,298...111,038,324 		JBrowse link
G GIP gastric inhibitory polypeptide ISO protein:increased expression:plasma (rat)
associated with Polycystic Ovary Syndrome; protein:increased expression:plasma (human)		 RGD PMID:3546047 PMID:18063845 PMID:19375579 RGD:2312547 RGD:2312551 RGD:2312588 NCBI chr12:25,160,783...25,167,952
Ensembl chr12:25,160,789...25,167,940 		JBrowse link
G GIPR gastric inhibitory polypeptide receptor susceptibility ISO DNA:polymorphism:intron 1 C>A (rs2302382) (human)
mRNA:splice variant:pancreatic islet (mouse)
mRNA:reduced expression:fat tissue (human)		 RGD PMID:12068290 PMID:17395281 PMID:17971513 PMID:19254363 RGD:2312612 RGD:2312615 RGD:2312616 RGD:737714 NCBI chr 6:52,022,667...52,033,959
Ensembl chr 6:52,022,681...52,033,954 		JBrowse link
G GJA5 gap junction protein alpha 5 ISO mRNA, protein:decreased expression:mesenteric artery RGD PMID:18324386 RGD:7207466 NCBI chr 4:99,854,129...99,871,288
Ensembl chr 4:99,854,392...99,871,286 		JBrowse link
G GLDC glycine decarboxylase ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:10873393 PMID:11286506 PMID:12126939 PMID:15670722 PMID:15791207 More... NCBI chr 1:215,608,854...215,715,062
Ensembl chr 1:215,608,849...215,715,059 		JBrowse link
G GLP1R glucagon like peptide 1 receptor ISO mRNA:decreased expression:hypothalamus medial zone
DNA:SNP:intron (rs2268641) (human)		 RGD PMID:15279492 PMID:23900445 RGD:1624351 RGD:405650675 NCBI chr 7:34,497,779...34,534,356
Ensembl chr 7:34,497,759...34,534,627 		JBrowse link
G GLRX glutaredoxin ISO protein:increased expression:renal visceral adipose: RGD PMID:23404913 RGD:9686064 NCBI chr 2:102,425,580...102,437,851
Ensembl chr 2:102,425,580...102,437,858 		JBrowse link
G GLUL glutamate-ammonia ligase ISO CTD Direct Evidence: marker/mechanism
protein:increased activity:skeletal muscle:activity is increased in Zucker fa/fa genetically obese but not dietary obese (fa/?) rats vs non-obese (fa/?) rats		 CTD
RGD		 PMID:15481771 PMID:20882379 RGD:2301479 NCBI chr 9:123,751,551...123,762,575
Ensembl chr 9:123,748,380...123,762,545 		JBrowse link
G GNAS GNAS complex locus ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:11784876 PMID:12970262 PMID:21525160 PMID:23281139 PMID:23796510 More... NCBI chr17:58,985,580...59,053,022
Ensembl chr17:58,998,981...59,053,021 		JBrowse link
G GNB3 G protein subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15961981 PMID:16141801 NCBI chr 5:63,863,656...63,871,352
Ensembl chr 5:63,863,661...63,870,433 		JBrowse link
G GNPDA2 glucosamine-6-phosphate deaminase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19079261 NCBI chr 8:35,192,509...35,219,527
Ensembl chr 8:35,193,659...35,216,206 		JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 ISO protein:increased expression:skeletal muscle tissue, T-tubule (rat) RGD PMID:23743348 RGD:11041118 NCBI chr 6:20,407,203...20,431,849
Ensembl chr 6:20,407,200...20,432,067 		JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial ISO mRNA:increased expression:pancreatic islet RGD PMID:9032096 RGD:2313659 NCBI chr14:122,538,600...122,582,390
Ensembl chr14:122,538,491...122,579,436 		JBrowse link
G GPR12 G protein-coupled receptor 12 ISO OMIM:601665 MouseDO NCBI chr11:4,426,797...4,427,953
Ensembl chr11:4,424,440...4,428,448 		JBrowse link
G GPR17 G protein-coupled receptor 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34144038 NCBI chr15:59,692,992...59,702,513
Ensembl chr15:59,692,996...59,701,265 		JBrowse link
G GPT2 glutamic--pyruvic transaminase 2 ISO protein:increased expression, activity:liver: RGD PMID:25865565 RGD:11342811 NCBI chr 6:37,625,428...37,669,695
Ensembl chr 6:37,625,436...37,669,663 		JBrowse link
G GPX1 glutathione peroxidase 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15184668 PMID:30298849 RGD:401960083 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433 		JBrowse link
G GPX3 glutathione peroxidase 3 treatment ISO mRNA:decreased expression:adipose tissue (rat)
CTD Direct Evidence: marker/mechanism
protein:decreased expression, activity:plasma (mouse)
mRNA:decreased expression:embryo, blastocyst
protein:decreased expression:plasma		 RGD
CTD		 PMID:11328671 PMID:18562625 PMID:19212806 PMID:19270708 PMID:21535898 More... RGD:2307430 RGD:2312633 RGD:401827913 RGD:401827923 RGD:5683906 NCBI chr16:71,980,467...71,989,011
Ensembl chr16:71,980,475...71,989,026 		JBrowse link
G GRIA4 glutamate ionotropic receptor AMPA type subunit 4 ISO ClinVar Annotator: match by term: Obesity ClinVar NCBI chr 9:35,442,060...35,803,989
Ensembl chr 9:35,442,091...35,805,357 		JBrowse link
G HADH hydroxyacyl-CoA dehydrogenase ISO protein:increased expression:skeletal muscle
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16088331 PMID:20882379 RGD:2302228 NCBI chr 8:113,952,561...114,005,510
Ensembl chr 8:113,950,034...114,005,511 		JBrowse link
G HCRT hypocretin neuropeptide precursor ISO mRNA:increased expression:perifornical nucleus
protein:increased expression:plasma:fasting patients, no change after weight loss due to gastric banding
protein:decreased expression:plasma:orexin A NOT orexin B polypeptide, expression inversely related to degree of obesity
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12560202 PMID:15970339 PMID:16135994 PMID:27071101 RGD:1358428 RGD:1600932 RGD:1600933 NCBI chr12:20,588,597...20,589,991
Ensembl chr12:20,588,027...20,589,988 		JBrowse link
G HDAC4 histone deacetylase 4 ISO mRNA,protein:decreased expression:mononuclear cell, adipose tissue: RGD PMID:24086512 RGD:9681453 NCBI chr15:138,378,237...138,657,266
Ensembl chr15:138,381,635...138,614,301 		JBrowse link
G HFE homeostatic iron regulator ISO associated with Diabetes Mellitus, Type 2;DNA:missense mutations:CDS:p.C282Y, p.H63D (human) RGD PMID:10705106 RGD:1601449 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,767,000 		JBrowse link
G HGF hepatocyte growth factor ISO protein:increased expression:serum RGD PMID:12706940 RGD:1642704 NCBI chr 9:98,437,771...98,513,573
Ensembl chr 9:98,438,143...98,513,564 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO associated with hepatocellular carcinoma;RNA:decreased expression:liver: RGD PMID:31321740 RGD:155882550 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G HK1 hexokinase 1 susceptibility ISO RGD PMID:131232 PMID:12524468 RGD:1601527 RGD:1601528 NCBI chr14:72,383,328...72,460,927
Ensembl chr14:72,351,246...72,460,924 		JBrowse link
G HK2 hexokinase 2 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:gastrocnemius		 CTD
RGD		 PMID:11319725 PMID:16555472 PMID:20882379 RGD:1624365 RGD:2313227 NCBI chr 3:68,155,656...68,231,187
Ensembl chr 3:68,153,835...68,231,615 		JBrowse link
G HMGA2 high mobility group AT-hook 2 ISO RGD PMID:10742101 RGD:1601569 NCBI chr 5:30,188,521...30,329,635 JBrowse link
G HMGB2 high mobility group box 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr14:16,709,966...16,712,288
Ensembl chr14:16,710,047...16,717,101 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 ISO protein:decreased activity:liver (rat) RGD PMID:1685984 RGD:2326155 NCBI chr16:27,936,225...27,957,261
Ensembl chr16:27,936,218...27,957,193 		JBrowse link
G HMOX1 heme oxygenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18334666 PMID:18375438 PMID:19171794
G HOXB5 homeobox B5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22484627 NCBI chr12:24,845,224...24,849,639
Ensembl chr12:24,845,225...24,847,918 		JBrowse link
G HP haptoglobin treatment ISO mRNA:increased expression:white fat
protein:increased expression:serum		 RGD PMID:11807829 PMID:15181041 PMID:17161237 PMID:19917068 RGD:1626339 RGD:1626346 RGD:1626349 RGD:9685197 NCBI chr 6:14,980,382...14,985,245 JBrowse link
G HRH3 histamine receptor H3 ISO RGD PMID:17189541 RGD:1626405 NCBI chr17:61,622,865...61,627,278
Ensembl chr17:61,622,938...61,627,278 		JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:adipose tissue:13-fold higher in obese subjects than controls, protein expression also increased		 CTD
RGD		 PMID:15131764 PMID:16612591 PMID:16914598 PMID:17628001 PMID:21786805 RGD:1625071 RGD:1625072 RGD:1625073 NCBI chr 9:133,231,451...133,278,396
Ensembl chr 9:133,231,451...133,278,396 		JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 resistance ISO transgenic mice expressing human HSD11B2
mRNA:increased expression:adipose tissue:subcutaneous not retroperitoneal fat		 RGD PMID:15793240 PMID:17208436 RGD:1625081 RGD:1625083 NCBI chr 6:28,084,087...28,089,256
Ensembl chr 6:28,083,955...28,089,671 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26655953 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B ISO protein:increase expression:arcuate nucleus RGD PMID:10564740 RGD:1626450 NCBI chr 1:88,597,510...88,598,682
Ensembl chr 1:88,596,237...88,601,757 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A no_association
susceptibility		 ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:-1438G>A
DNA:SNP:intron (rs912127) (human)		 CTD
RGD		 PMID:16328014 PMID:16491645 PMID:17097612 PMID:23900445 RGD:1624369 RGD:1624370 RGD:405650675 NCBI chr11:20,555,939...20,620,225
Ensembl chr11:20,555,963...20,619,625 		JBrowse link
G HTR2C 5-hydroxytryptamine receptor 2C susceptibility ISO associated with Schizophrenia and Psychotic Disorders;DNA:polymorphisms:promoter:multiple
DNA:polymorphism:promoter:-759C>T
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:15048662 PMID:17016522 PMID:17702092 PMID:19142110 RGD:1624982 RGD:1624991 NCBI chr  X:94,053,415...94,313,352
Ensembl chr  X:94,053,456...94,313,355 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:submandibular gland (rat)
protein:increased secretion:plasma (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:11782876 PMID:20004360 PMID:20973827 RGD:4145329 RGD:4145463 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205 		JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 ISO RGD PMID:14969338 RGD:1626475 NCBI chr15:111,341,153...111,362,330
Ensembl chr15:111,341,153...111,362,296 		JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27020609 NCBI chr17:9,245,283...9,260,140
Ensembl chr17:9,245,196...9,260,473 		JBrowse link
G IFNG interferon gamma ISO associated with Asthma;protein:increased expression:serum RGD PMID:19575934 RGD:2311494 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO mRNA:decreased expression:heart (rat) RGD PMID:11009458 RGD:12904882 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058 		JBrowse link
G IGF2 insulin like growth factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11528401 NCBI chr 2:1,469,183...1,496,417 JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:17259371 PMID:17426323 PMID:22537059 RGD:1626478 RGD:1626479 NCBI chr15:118,822,092...118,850,985
Ensembl chr15:118,822,047...118,850,976 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO mRNA, protein:decreased expression:pancreatic fat pad RGD PMID:22067319 RGD:10402755 NCBI chr18:50,002,921...50,009,425
Ensembl chr18:50,003,022...50,010,690 		JBrowse link
G IGFBP6 insulin like growth factor binding protein 6 ISO human transgene overexpressed in mouse brain RGD PMID:15889232 RGD:2301717 NCBI chr 5:18,352,884...18,357,225
Ensembl chr 5:18,352,400...18,357,225 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta ISO protein:increased expression:liver: RGD PMID:15685173 RGD:10045952 NCBI chr17:11,289,607...11,348,557
Ensembl chr17:11,289,690...11,348,549 		JBrowse link
G IL10 interleukin 10 ISO protein:increase expression:serum RGD PMID:18787467 PMID:28843383 RGD:14975146 RGD:2308945 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378 		JBrowse link
G IL15 interleukin 15 ISO mRNA, protein:altered expression:skeletal muscle, plasma RGD PMID:18697873 RGD:2313573 NCBI chr 8:85,666,963...85,740,980
Ensembl chr 8:85,667,321...85,678,461 		JBrowse link
G IL18 interleukin 18 treatment ISO RGD PMID:16732281 PMID:20490358 RGD:14695532 RGD:7175343 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO mRNA, protein:increased expression:adipose tissue RGD PMID:12716739 PMID:12975454 RGD:1626664 RGD:1626665
G IL6 interleukin 6 ISO DNA:polymorphism>promoter:174G>C
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human)
mRNA:increased expression:islet of Langerhans		 RGD
CTD		 PMID:16493118 PMID:19228869 PMID:20141834 PMID:21826222 PMID:24042701 RGD:10402828 RGD:1601582 RGD:2307257 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G IL6R interleukin 6 receptor susceptibility ISO DNA:duplication
DNA:polymorphism: :p.D358A
protein:increased expression:serum
DNA:SNP, haplotypes:promoter:-208G>A (rs4845617) (human)		 RGD PMID:12917504 PMID:16817825 PMID:17434052 PMID:17984249 RGD:10402807 RGD:1625428 RGD:1625429 RGD:1625430 NCBI chr 4:95,322,426...95,381,393
Ensembl chr 4:95,322,433...95,381,282 		JBrowse link
G IL7 interleukin 7 ISO CTD Direct Evidence: therapeutic CTD PMID:20376352 NCBI chr 4:57,677,895...57,744,713
Ensembl chr 4:57,684,796...57,744,709 		JBrowse link
G INPP5E inositol polyphosphate-5-phosphatase E treatment ISO protein:increased expression:skeletal muscle, white adipose tissue
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:19668215 PMID:23349329 RGD:12911211
G INPPL1 inositol polyphosphate phosphatase like 1 ISO DNA:SNPs: :rs2276047,snp8,rs9886(human) RGD PMID:15220217 RGD:1626127 NCBI chr 9:6,793,971...6,807,286
Ensembl chr 9:6,793,069...6,808,028 		JBrowse link
G INS insulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2777199 PMID:8923850 PMID:11528401 PMID:29035695 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841 		JBrowse link
G IRS1 insulin receptor substrate 1 ISO protein:decreased tyrosine phosphorylation, increased serine phosphorylation:skeletal muscle
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:22982470 PMID:23954404 RGD:7207062 NCBI chr15:128,245,846...128,307,321
Ensembl chr15:128,245,846...128,307,284 		JBrowse link
G ITGAM integrin subunit alpha M ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:monocyte (human)		 CTD
RGD		 PMID:21446916 PMID:29035695 RGD:329901665 NCBI chr 3:17,216,719...17,272,134
Ensembl chr 3:17,204,610...17,268,018 		JBrowse link
G ITIH4 inter-alpha-trypsin inhibitor heavy chain 4 ISO RGD PMID:22134356 RGD:11352709 NCBI chr13:34,928,455...34,948,250
Ensembl chr13:34,928,439...34,948,229 		JBrowse link
G JAK2 Janus kinase 2 ISO protein:decreased expression:hypothalamus
mRNA:decreased expression:omental adipose tissue:by microarray		 RGD PMID:14630696 PMID:23397595 RGD:10411893 RGD:1627661 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148 		JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit ISO mRNA,protein:increased expression:heart RGD PMID:30629164 RGD:401900736 NCBI chr 2:59,530,991...59,532,846 JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:7889573 PMID:9024139 PMID:9927399 PMID:10753933 PMID:10973849 More... NCBI chr18:6,242,826...6,279,154
Ensembl chr18:6,243,524...6,279,111 		JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27605626 NCBI chr14:79,345,382...80,106,337
Ensembl chr14:79,352,005...80,106,295 		JBrowse link
G KCTD15 potassium channel tetramerization domain containing 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19079261 NCBI chr 6:43,528,677...43,545,834
Ensembl chr 6:43,529,806...43,544,186 		JBrowse link
G KDM3A lysine demethylase 3A ISO OMIM:601665 RGD
MouseDO		 PMID:19875498 RGD:9590220 NCBI chr 3:58,300,109...58,355,000
Ensembl chr 3:58,302,949...58,354,945 		JBrowse link
G KIF4A kinesin family member 4A ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:25741868 NCBI chr  X:56,319,453...56,447,560
Ensembl chr  X:56,319,529...56,447,553 		JBrowse link
G KITLG KIT ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:23954404 NCBI chr 5:94,016,992...94,110,219
Ensembl chr 5:94,017,387...94,110,214 		JBrowse link
G LACTB lactamase beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18344982 NCBI chr 1:108,909,690...108,924,509
Ensembl chr 1:108,909,693...108,924,511 		JBrowse link
G LBP lipopolysaccharide binding protein treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19917068 PMID:23349936 RGD:9685197 NCBI chr17:41,398,935...41,429,467
Ensembl chr17:41,398,791...41,429,551 		JBrowse link
G LCN2 lipocalin 2 ISO mRNA:increased expression:epididymal fat pad, adipose cell (rat)
mRNA:decreased expression:ovary, testicle
protein:increased expression:serum		 RGD PMID:18292240 PMID:21143924 PMID:32627017 RGD:126790490 RGD:126790530 RGD:2316514 NCBI chr 1:268,609,975...268,614,651
Ensembl chr 1:268,609,887...268,614,644 		JBrowse link
G LDLR low density lipoprotein receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25554529 NCBI chr 2:69,828,348...69,864,823
Ensembl chr 2:69,828,332...69,864,827 		JBrowse link
G LEP leptin treatment
no_association		 ISO mouse protein in a rat model
in a US Caucasian population
ClinVar Annotator: match by term: Monogenic Non-Syndromic Obesity		 RGD
ClinVar		 PMID:10029567 PMID:15910756 PMID:23793169 PMID:25741868 PMID:28492532 RGD:10053612 RGD:10053638 RGD:1643130 NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,323 		JBrowse link
G LEPR leptin receptor susceptibility
no_association
treatment
sexual_dimorphism
disease_progression		 ISO DNA:polymorphism:exon:p.Q223R (human)
compared to BN
ClinVar Annotator: match by term: Monogenic Non-Syndromic Obesity | ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity disorder		 RGD
ClinVar		 PMID:8666155 PMID:9545018 PMID:11354636 PMID:11380591 PMID:11443193 More... RGD:10412018 RGD:10412023 RGD:12911217 RGD:401965412 RGD:5128855 RGD:7365117 NCBI chr 6:146,802,297...146,896,152
Ensembl chr 6:146,801,954...146,895,995 		JBrowse link
G LEPROT leptin receptor overlapping transcript ISO ClinVar Annotator: match by term: Monogenic Non-Syndromic Obesity ClinVar PMID:25741868 PMID:28492532 NCBI chr 6:146,974,641...146,987,261
Ensembl chr 6:146,974,639...146,987,242 		JBrowse link
G LIPC lipase C, hepatic type ISO protein:altered expression:liver, plasma (rat)
associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:plasma (human)		 RGD PMID:11544558 PMID:12843191 RGD:2308784 RGD:2308835 NCBI chr 1:113,433,684...113,604,139
Ensembl chr 1:113,433,687...113,583,963 		JBrowse link
G LIPE lipase E, hormone sensitive type ISO mRNA:decreased expression:white fat RGD PMID:17712951 RGD:2313580 NCBI chr 6:49,543,671...49,560,126
Ensembl chr 6:49,540,708...49,560,125 		JBrowse link
G LIPG lipase G, endothelial type ISO protein:increased expression:plasma RGD PMID:16772345 RGD:1641819 NCBI chr 1:99,081,940...99,110,671
Ensembl chr 1:99,081,938...99,110,874 		JBrowse link
G LOC100516390 ankyrin repeat domain-containing protein 26 ISO OMIM:601665 RGD
MouseDO		 PMID:18162531 RGD:9681744 NCBI chr10:48,694,806...48,795,783 JBrowse link
G LOC106504546 serpin A12 treatment ISO RGD PMID:16030142 RGD:1547845 NCBI chr 7:115,720,892...115,734,810
Ensembl chr 7:115,721,098...115,734,978 		JBrowse link
G LOC110255234 liver carboxylesterase-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:20975297
G LOC110256000 membrane primary amine oxidase-like ISO RGD PMID:17977742 RGD:2313916 NCBI chr12:19,996,324...20,007,006 JBrowse link
G LOC110258578 interleukin-1 beta-like treatment ISO protein:increased expression:kidney (rat)
protein:increased expression:plasma (mouse)		 RGD PMID:16567518 PMID:20490358 PMID:23150506 PMID:24146106 PMID:28843383 RGD:10450599 RGD:14975146 RGD:1626637 RGD:7175086 RGD:7175343
G LPL lipoprotein lipase treatment ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:white fat		 CTD
RGD		 PMID:17712951 PMID:18344982 PMID:18952837 PMID:27160499 PMID:28514832 RGD:13793401 RGD:13794378 RGD:2313300 RGD:2313580 NCBI chr14:4,104,761...4,134,964
Ensembl chr14:4,104,772...4,135,814 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO protein:increased phosphorylation:endometrium (human) RGD PMID:20074784 RGD:13782055 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO protein:increased phosphorylation:endometrium (human) RGD PMID:20074784 RGD:13782055 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G MAPT microtubule associated protein tau ISO RGD PMID:25257559 RGD:13800921 NCBI chr12:17,098,259...17,211,483
Ensembl chr12:17,095,587...17,211,373 		JBrowse link
G MBL2 mannose binding lectin 2 ISO DNA:missense mutations:cds:p.R52C, p.G57E (human) RGD PMID:16955210 RGD:4889156 NCBI chr14:97,103,926...97,107,635
Ensembl chr14:97,102,823...97,108,083 		JBrowse link
G MC3R melanocortin 3 receptor susceptibility ISO DNA:missense mutations:cds:p.T6K, p.V81I (human)
ClinVar Annotator: match by term: Obesity		 RGD
ClinVar		 PMID:16123355 RGD:6484587 NCBI chr17:56,868,525...56,869,605
Ensembl chr17:56,868,525...56,869,605 		JBrowse link
G MC4R melanocortin 4 receptor ISO ClinVar Annotator: match by term: Monogenic Obesity | ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity, autosomal dominant
ClinVar Annotator: match by term: Monogenic Non-Syndromic Obesity | ClinVar Annotator: match by term: Monogenic Obesity | ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity, autosomal dominant
ClinVar Annotator: match by term: Monogenic Obesity | ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity, autosomal dominant | ClinVar Annotator: match by term: SIM1-related condition
ClinVar Annotator: match by term: Monogenic Obesity | ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity due to melanocortin 4 receptor deficiency | ClinVar Annotator: match by term: Obesity, autosomal dominant		 ClinVar PMID:9267995 PMID:10078568 PMID:10199800 PMID:10577903 PMID:10585465 More... NCBI chr 1:160,772,013...160,774,124
Ensembl chr 1:160,772,013...160,774,124 		JBrowse link
G MCHR1 melanin concentrating hormone receptor 1 ISO mRNA:increased expression:hypothalamus RGD PMID:15363890 RGD:1624360 NCBI chr 5:7,735,752...7,752,006
Ensembl chr 5:7,735,825...7,738,701 		JBrowse link
G ME1 malic enzyme 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19270708 NCBI chr 1:82,799,878...82,989,895
Ensembl chr 1:82,799,684...82,991,085 		JBrowse link
G MFN2 mitofusin 2 ISO mRNA:decreased expression:skeletal muscle tissue (human)
mRNA:decreased expression:liver (rat)		 RGD PMID:12598526 PMID:25336449 RGD:12880438 RGD:1601412 NCBI chr 6:72,026,512...72,056,439
Ensembl chr 6:72,028,499...72,056,438 		JBrowse link
G MGRN1 mahogunin ring finger 1 ISO RGD PMID:16638826 RGD:1641947 NCBI chr 3:37,694,798...37,748,106
Ensembl chr 3:37,694,808...37,748,067 		JBrowse link
G MIF macrophage migration inhibitory factor ISO DNA:polymorphisms:promoter
mRNA, protein:increased expression:mononuclear cell, plasma		 RGD PMID:15472203 PMID:16247506 RGD:1641950 RGD:1641953 NCBI chr14:49,840,303...49,841,063
Ensembl chr14:49,840,305...49,841,068 		JBrowse link
G MIR107 microRNA mir-107 ISO RNA:decreased expression:liver: RGD PMID:21120623 RGD:14975298 NCBI chr14:101,420,743...101,420,829
Ensembl chr14:101,420,743...101,420,829 		JBrowse link
G MIR125A microRNA mir-125a ISO RNA:decreased expression:liver RGD PMID:31988048 RGD:21403676 NCBI chr 6:58,331,566...58,331,645
Ensembl chr 6:58,331,566...58,331,645 		JBrowse link
G MIR130A microRNA mir-130a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28242765 NCBI chr 2:13,296,695...13,296,773
Ensembl chr 2:13,296,695...13,296,773 		JBrowse link
G MIR155 microRNA mir-155 ISO miRNA:decreased expression:serum RGD PMID:27856635 PMID:28970282 PMID:29479888 RGD:21079445 RGD:21079446 RGD:24922220 NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902 		JBrowse link
G MIR184 microRNA mir-184 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23954404 NCBI chr 7:48,345,017...48,345,099
Ensembl chr 7:48,345,017...48,345,099 		JBrowse link
G MIR21 microRNA mir-21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23954404 NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358 		JBrowse link
G MIR23A microRNA mir-23a ISO associated with hepatocellular carcinoma;RNA:increased expression:exosome, liver: RGD PMID:31321740 RGD:155882550 NCBI chr 2:65,308,117...65,308,186
Ensembl chr 2:65,308,117...65,308,186 		JBrowse link
G MIR23B microRNA mir-23b ISO associated with hepatocellular carcinoma;RNA:increased expression:exosome, liver: RGD PMID:31321740 RGD:155882550 NCBI chr10:27,080,197...27,080,276
Ensembl chr10:27,080,197...27,080,276 		JBrowse link
G MKKS MKKS centrosomal shuttling protein no_association ISO unlikely to play a major role in the pathogenesis of nonsyndromic obesity
protein:substitution:A242S possible contribution
OMIM:601665		 RGD
MouseDO		 PMID:10973251 PMID:15483080 RGD:1581208 RGD:1601414 NCBI chr17:19,341,024...19,363,007
Ensembl chr17:19,341,636...19,362,871 		JBrowse link
G MMP19 matrix metallopeptidase 19 ISO mRNA:increased expression:adipose tissue RGD PMID:12529376 PMID:15169894 RGD:1642022 RGD:1642023 NCBI chr 5:21,279,514...21,285,943
Ensembl chr 5:21,280,130...21,285,774 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma		 CTD
RGD		 PMID:17512313 PMID:21156398 RGD:1642026 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788 		JBrowse link
G MMUT methylmalonyl-CoA mutase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr 7:43,597,313...43,624,603
Ensembl chr 7:43,597,246...43,624,671 		JBrowse link
G MRC1 mannose receptor C-type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29035695 NCBI chr10:44,107,926...44,226,734
Ensembl chr10:44,107,072...44,226,733 		JBrowse link
G MT-CYB mitochondrially encoded cytochrome b ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:12905068 PMID:25741868 NCBI chr MT:15,342...16,481
Ensembl chr MT:15,342...16,481 		JBrowse link
G MT-ND1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 ISO DNA:missense mutation: :p.A64V (human) RGD PMID:16060290 RGD:2300401 NCBI chr MT:3,922...4,876
Ensembl chr MT:3,922...4,876 		JBrowse link
G MT3 metallothionein 3 ISO RGD PMID:21726645 RGD:6480475 NCBI chr 6:18,634,735...18,636,134
Ensembl chr 6:18,634,261...18,636,131 		JBrowse link
G MTCH2 mitochondrial carrier 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19079261 NCBI chr 2:14,982,991...15,005,214
Ensembl chr 2:14,983,154...15,005,213 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO mRNA, protein:decreased expression:hypothalamus RGD PMID:25807795 RGD:11570513 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888 		JBrowse link
G MTTP microsomal triglyceride transfer protein susceptibility ISO DNA:polymorphisms RGD PMID:15635487 RGD:1625486 NCBI chr 8:120,820,660...120,871,468
Ensembl chr 8:120,820,656...120,879,388 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO mRNA:decreased expression:pancreas (rat) RGD PMID:22421529 RGD:7240547 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078 		JBrowse link
G MYH10 myosin heavy chain 10 ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:25741868 NCBI chr12:53,647,579...53,781,552 JBrowse link
G MYH9 myosin heavy chain 9 ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:25741868 PMID:31064749 NCBI chr 5:11,365,603...11,456,475
Ensembl chr 5:11,360,660...11,456,472 		JBrowse link
G MYOD1 myogenic differentiation 1 ISO mRNA:decreased expression:plantaris RGD PMID:18508911 PMID:22349736 RGD:2313320 RGD:9686079 NCBI chr 2:41,422,522...41,424,236
Ensembl chr 2:41,415,775...41,424,435 		JBrowse link
G MYOG myogenin ISO mRNA:decreased expression:plantaris RGD PMID:18508911 RGD:2313320 NCBI chr 9:113,783,233...113,785,312
Ensembl chr 9:113,782,284...113,787,340 		JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum		 CTD
RGD		 PMID:17618961 PMID:23834033 RGD:1642336 NCBI chr 9:106,119,896...106,162,126
Ensembl chr 9:106,119,899...106,294,586 		JBrowse link
G NCF2 neutrophil cytosolic factor 2 ISO protein:increased expression:artery RGD PMID:17515452 RGD:2314435 NCBI chr 9:124,776,516...124,813,358
Ensembl chr 9:124,776,534...124,812,923 		JBrowse link
G NCOA1 nuclear receptor coactivator 1 ISO OMIM:601665 MouseDO NCBI chr 3:113,997,214...114,251,080
Ensembl chr 3:113,999,253...114,250,298 		JBrowse link
G NCOA3 nuclear receptor coactivator 3 ISO DNA:polymorphism:CDS:C-terminus polyglutamine repeat, combination of long polyglutamine repeat in NCOA3 and homozygous A1/A1 Progesterone Receptor genotype associated with obesity in 301 postmenopausal women with breast cancer RGD PMID:14557830 RGD:1642050 NCBI chr17:49,528,275...49,660,471
Ensembl chr17:49,528,179...49,663,200 		JBrowse link
G NDUFB6 NADH:ubiquinone oxidoreductase subunit B6 ISO mRNA:decreased expression:epididymal fat pad RGD PMID:20559011 RGD:13822707 NCBI chr10:33,849,206...33,865,080
Ensembl chr10:33,802,051...33,865,385 		JBrowse link
G NEGR1 neuronal growth regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19079261 NCBI chr 6:140,780,397...141,652,414
Ensembl chr 6:140,780,723...141,647,820 		JBrowse link
G NEIL1 nei like DNA glycosylase 1 ISO CTD Direct Evidence: marker/mechanism
OMIM:601665		 CTD
MouseDO		 PMID:16446448 PMID:21285402 NCBI chr 7:58,261,761...58,269,001
Ensembl chr 7:58,261,769...58,268,522 		JBrowse link
G NEUROD1 neuronal differentiation 1 ISO mRNA:increased expression:pancreas RGD PMID:15979049 RGD:1625044 NCBI chr15:87,175,629...87,179,953
Ensembl chr15:87,175,765...87,179,959 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO protein:decreased expression:hepatocyte:
protein:decreased expression:liver macrophage:		 RGD PMID:32102936 RGD:21201281 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183 		JBrowse link
G NHLH2 nescient helix-loop-helix 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20808804 NCBI chr 4:104,852,287...104,858,042
Ensembl chr 4:104,857,635...104,858,042 		JBrowse link
G NMB neuromedin B susceptibility ISO protein:increased expression:central hypothalamus:concentrations higher in obese (fa/fa) than in lean (Fa/?) male Zucker rats, not affected by weight loss
DNA:polymorphism:CDS:401G>A, silent mutation in stop codon, associated with body weight (p=0.02)
DNA:polymorphism:CDS:217C>A, amino acid P73T, associated with disinhibition toward food (p=0.03), susceptibility to hunger (p=0.01) and increased percent body fat (p<0.05)		 RGD PMID:1709601 PMID:11194934 PMID:15585758 RGD:1642059 RGD:1642062 RGD:1642063 NCBI chr 7:52,880,817...52,886,651
Ensembl chr 7:52,883,128...52,886,642 		JBrowse link
G NMU neuromedin U susceptibility ISO DNA:polymorphisms:cds:p.R165W,p.A19E RGD PMID:15448684 PMID:16984985 PMID:17706946 RGD:1642093 RGD:1642094 RGD:1642095 NCBI chr 8:54,952,333...54,978,577
Ensembl chr 8:54,952,339...54,978,551 		JBrowse link
G NNT nicotinamide nucleotide transhydrogenase ISO protein:decreased expression:gastrocnemius, soleus RGD PMID:25761734 RGD:13513980 NCBI chr16:28,157,192...28,248,732
Ensembl chr16:28,157,318...28,250,961 		JBrowse link
G NOS1 nitric oxide synthase 1 ISO RGD PMID:16316351 RGD:1642132 NCBI chr14:35,112,898...35,299,297
Ensembl chr14:35,113,184...35,295,944 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO protein:increased expression:sputum
protein:increased expression:liver, gastrocnemius muscle, adipose tissue (mouse)		 RGD PMID:18098375 PMID:21896669 RGD:4891935 RGD:5509059 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G NOS3 nitric oxide synthase 3 treatment ISO protein:decreased expression:artery RGD PMID:17623751 PMID:29180887 RGD:13504728 RGD:2292133 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
G NOX4 NADPH oxidase 4 treatment ISO RGD PMID:30298849 RGD:401960083 NCBI chr 9:22,622,105...22,776,691
Ensembl chr 9:22,624,212...22,776,534 		JBrowse link
G NPC1 NPC intracellular cholesterol transporter 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19151714 NCBI chr 6:108,403,126...108,450,486
Ensembl chr 6:108,402,879...108,450,990 		JBrowse link
G NPPA natriuretic peptide A ISO associated with Heart Failure; RGD PMID:23566312 RGD:7247714 NCBI chr 6:71,919,557...71,921,345
Ensembl chr 6:71,918,845...71,921,405 		JBrowse link
G NPPB natriuretic peptide B treatment ISO associated with Diabetes Mellitus, Type 2
mRNA:decreased expression:heart
associated with hypoxia; protein:increased expression:blood serum (rat)		 RGD PMID:21959345 PMID:24009719 PMID:33310031 RGD:329955450 RGD:5685647 RGD:7327171 NCBI chr 6:71,930,374...71,931,843
Ensembl chr 6:71,930,382...71,932,254 		JBrowse link
G NPY neuropeptide Y ISO mRNA, protein:increased expression:hypothalamus RGD PMID:17447163 RGD:10448938 NCBI chr18:47,985,796...47,993,726
Ensembl chr18:47,985,725...47,992,667 		JBrowse link
G NPY1R neuropeptide Y receptor Y1 susceptibility ISO associated with Hyperinsulinemia
mRNA:increased expression:hypothalamus
CTD Direct Evidence: marker/mechanism
OMIM:601665		 RGD
CTD
MouseDO		 PMID:9861026 PMID:17447163 PMID:20975297 RGD:10448938 RGD:1642306 NCBI chr 8:52,152,649...52,163,080
Ensembl chr 8:52,152,646...52,162,328 		JBrowse link
G NPY2R neuropeptide Y receptor Y2 ISO mRNA:increased expression:hypothalamus
DNA:SNP:promoter:−4448C>A, NCBI refSNP ID=rs12649641; Danish white subjects		 RGD PMID:17019604 PMID:17447163 RGD:10448938 RGD:1642379 NCBI chr 8:74,039,959...74,048,398
Ensembl chr 8:74,039,616...74,047,817 		JBrowse link
G NPY5R neuropeptide Y receptor Y5 susceptibility ISO mRNA:increased expression:hypothalamus
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms
DNA:SNP:utr (Y5R1c52) (human)		 RGD
CTD		 PMID:10849579 PMID:17447163 PMID:23900445 RGD:10448938 RGD:1625493 RGD:405650675 NCBI chr 8:52,173,906...52,183,336
Ensembl chr 8:52,174,434...52,183,341 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17405841 NCBI chr 6:17,292,962...17,302,593
Ensembl chr 6:17,292,770...17,302,590 		JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 ISO ClinVar Annotator: match by term: Monogenic Obesity | ClinVar Annotator: match by term: NR0B2-related condition | ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity, mild, early-onset OMIM
ClinVar		 PMID:11136233 PMID:20233523 PMID:25741868 PMID:28492532 PMID:33094510 NCBI chr 6:84,225,670...84,228,156
Ensembl chr 6:84,225,694...84,228,481 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 disease_progression ISO mRNA:increased expression:liver (rat)
DNA:polymorphism:multiple		 RGD PMID:17108812 PMID:20939869 PMID:25612518 RGD:13506790 RGD:15045599 RGD:1626248 NCBI chr 6:55,238,536...55,245,457
Ensembl chr 6:55,239,500...55,245,456 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 disease_progression ISO DNA:polymorphism:multiple
mRNA:increased expression:liver (rat)		 RGD PMID:17108812 PMID:25612518 RGD:15045599 RGD:1626248 NCBI chr 2:15,315,283...15,336,785
Ensembl chr 2:15,315,282...15,334,820 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 disease_progression ISO mRNA:increased expression:liver (rat) RGD PMID:25612518 RGD:15045599 NCBI chr 5:83,607,222...83,732,668
Ensembl chr 5:83,604,294...83,684,604 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20869355 NCBI chr13:140,373,571...140,406,129
Ensembl chr13:140,364,075...140,406,112 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20869355 NCBI chr 4:89,226,314...89,231,781
Ensembl chr 4:89,226,690...89,236,431 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 no_association ISO associated with Depressive Disorder, Major;DNA:SNP:intron:IVS2+646C>G (human)
protein:polymorphism:N363S 		RGD PMID:16725041 PMID:18246526 PMID:20723946 RGD:1601498 RGD:4892206 RGD:7174717 NCBI chr 2:144,822,937...144,956,451
Ensembl chr 2:144,822,939...144,956,451 		JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 treatment ISO RGD PMID:30298849 RGD:401960083 NCBI chr 8:80,303,172...80,669,050
Ensembl chr 8:80,312,234...80,668,412 		JBrowse link
G NRF1 nuclear respiratory factor 1 treatment ISO mRNA:decreased expression:left ventricle myocardium (rat) RGD PMID:33310031 RGD:329955450 NCBI chr18:19,008,408...19,142,678
Ensembl chr18:18,998,930...19,142,628 		JBrowse link
G NRXN1 neurexin 1 ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:25741868 NCBI chr 3:89,799,426...90,914,205
Ensembl chr 3:89,803,519...90,382,034 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Obesity ClinVar NCBI chr10:30,030,050...30,429,938
Ensembl chr10:30,033,405...30,429,882 		JBrowse link
G NUCB2 nucleobindin 2 ISO protein:increased expression:adipose tissue: RGD PMID:22641054 RGD:9831187 NCBI chr 2:41,782,594...41,829,829 JBrowse link
G NUDC nuclear distribution C, dynein complex regulator ISO ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity, mild, early-onset
ClinVar Annotator: match by term: Monogenic Obesity | ClinVar Annotator: match by term: NR0B2-related condition | ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity, mild, early-onset		 ClinVar PMID:11136233 PMID:20233523 PMID:25741868 PMID:28492532 PMID:33094510 NCBI chr 6:84,238,695...84,252,046
Ensembl chr 6:84,238,430...84,252,046 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29709520 NCBI chr13:66,038,669...66,045,478 JBrowse link
G OPRM1 opioid receptor mu 1 treatment ISO DNA, mRNA:hypermethylation, increased expression:promoter, hypothalamus
DNA:hypermethylation:promoter, peripheral blood mononuclear cell		 RGD PMID:16876155 PMID:31258545 RGD:401827956 RGD:401842391 NCBI chr 1:12,634,125...12,702,295
Ensembl chr 1:12,528,672...12,702,443 		JBrowse link
G OTC ornithine transcarbamylase ISO protein:increased activity:liver (rat) RGD PMID:1330956 RGD:4144087 NCBI chr  X:34,322,398...34,391,711
Ensembl chr  X:34,322,298...34,391,821 		JBrowse link
G OXCT1 3-oxoacid CoA-transferase 1 ISO mRNA:decreased expression:thalamus (rat) RGD PMID:19219059 RGD:2326191 NCBI chr16:26,514,497...26,659,739
Ensembl chr16:26,512,401...26,659,808 		JBrowse link
G PACS1 phosphofurin acidic cluster sorting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23563609 NCBI chr 2:6,138,345...6,277,309
Ensembl chr 2:6,138,351...6,174,632 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20561897 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,160...14,241,196 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr17:57,930,507...57,936,523
Ensembl chr17:57,930,432...57,936,522 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 ISO ClinVar Annotator: match by term: Monogenic Non-Syndromic Obesity | ClinVar Annotator: match by term: Obesity ClinVar PMID:25741868 PMID:28492532 NCBI chr 2:103,004,794...103,050,707
Ensembl chr 2:103,004,794...103,050,839 		JBrowse link
G PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor ISO protein:increased expression:brainstem RGD PMID:11680901 PMID:15012590 RGD:1642350 RGD:1642351 NCBI chr  X:42,947,688...42,952,222
Ensembl chr  X:42,947,692...42,949,024 		JBrowse link
G PDE3A phosphodiesterase 3A ISO mRNA:decreased expression:heart RGD PMID:9648839 RGD:2300415 NCBI chr 5:52,413,503...52,737,771
Ensembl chr 5:52,409,882...52,738,406 		JBrowse link
G PDE9A phosphodiesterase 9A treatment ISO RGD PMID:34618683 RGD:242170038 NCBI chr13:205,938,342...206,034,981
Ensembl chr13:205,938,348...206,034,976 		JBrowse link
G PDP1 pyruvate dehydrogenase phosphatase catalytic subunit 1 ISO protein:decreased activity:circulating lymphocytes RGD PMID:15897476 RGD:1642637 NCBI chr 4:42,769,232...42,777,936
Ensembl chr 4:42,764,441...42,777,904 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 ISO mRNA:increased expression:exocrine pancreas (human) RGD PMID:15979049 RGD:1625044 NCBI chr11:5,303,609...5,309,063
Ensembl chr11:5,303,609...5,309,063 		JBrowse link
G PEX11A peroxisomal biogenesis factor 11 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:30585412 NCBI chr 7:55,256,239...55,264,253
Ensembl chr 7:55,256,220...55,264,247 		JBrowse link
G PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr10:64,776,315...64,859,118
Ensembl chr10:64,776,315...64,802,287 		JBrowse link
G PGF placental growth factor ISO associated with pancreatic cancer;protein:increased expression:plasma (human)
associated with Pre-eclampsia;protein:increased expression:serum		 RGD PMID:16020476 PMID:16769024 PMID:26861455 RGD:14349030 RGD:1642384 RGD:1642385 NCBI chr 7:98,149,510...98,162,784
Ensembl chr 7:98,148,994...98,162,741 		JBrowse link
G PGR progesterone receptor ISO DNA:polymorphism:CDS:PROGINS polymorphism, combination of long polyglutamine repeat in NCOA3 and homozygous A1/A1 PGR PROGINS genotype associated with obesity in 301 postmenopausal women with breast cancer RGD PMID:14557830 RGD:1642050 NCBI chr 9:32,035,684...32,129,776
Ensembl chr 9:32,035,684...32,129,221 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:21949398 RGD:6482700 NCBI chr 9:106,698,200...106,748,217
Ensembl chr 9:106,698,207...106,745,099 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO protein:decreased expression:soleus
protein:decreased tyrosine phosphorylation:skeletal muscle, liver		 RGD PMID:9399964 PMID:16123202 RGD:1625218 RGD:1625220 NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,511,521...46,523,609 		JBrowse link
G PKLR pyruvate kinase L/R ISO mRNA, protein:decreased expression:liver RGD PMID:12958186 RGD:1625583 NCBI chr 4:94,536,978...94,546,561
Ensembl chr 4:94,537,019...94,546,555 		JBrowse link
G PLAT plasminogen activator, tissue type ISO RGD PMID:12818410 RGD:2311677 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor ISO RGD PMID:21372607 RGD:6484121 NCBI chr 6:50,489,773...50,505,453
Ensembl chr 6:50,489,777...50,505,418 		JBrowse link
G PLIN1 perilipin 1 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:snp:intron:g.11482G>A (human)		 CTD
RGD		 PMID:11371650 PMID:15001633 PMID:15985482 RGD:1581041 RGD:737723 NCBI chr 7:55,237,517...55,250,797
Ensembl chr 7:55,236,348...55,250,797 		JBrowse link
G PLSCR3 phospholipid scramblase 3 ISO OMIM:601665 MouseDO NCBI chr12:52,719,060...52,724,570
Ensembl chr12:52,719,064...52,724,982 		JBrowse link
G PMCH pro-melanin concentrating hormone ISO CTD Direct Evidence: marker/mechanism
associated with Hyperphagia
associated with Hyperphagia;protein:increased expression:hypothalamus		 CTD
RGD		 PMID:12355323 PMID:12453827 PMID:15363890 RGD:1624360 RGD:1642486 NCBI chr 5:82,018,915...82,020,267
Ensembl chr 5:82,018,915...82,020,266 		JBrowse link
G PNLIP pancreatic lipase susceptibility ISO RGD PMID:15883013 RGD:1358859 NCBI chr14:126,771,920...126,789,097
Ensembl chr14:126,772,911...126,790,001 		JBrowse link
G PNPLA3 patatin like phospholipase domain containing 3 ISO RGD PMID:11431482 RGD:14985224 NCBI chr 5:5,075,608...5,092,599
Ensembl chr 5:5,075,622...5,092,515 		JBrowse link
G POGZ pogo transposable element derived with ZNF domain ISO ClinVar Annotator: match by term: Obesity ClinVar NCBI chr 4:97,776,579...97,833,287
Ensembl chr 4:97,776,589...97,833,282 		JBrowse link
G POMC proopiomelanocortin ISO ClinVar Annotator: match by term: Monogenic Non-Syndromic Obesity | ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity, early-onset, susceptibility to
ClinVar Annotator: match by term: Monogenic Non-Syndromic Obesity | ClinVar Annotator: match by term: Monogenic Obesity | ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity disorder		 ClinVar
OMIM		 PMID:8302318 PMID:9620771 PMID:9768693 PMID:10193875 PMID:11941477 More... NCBI chr 3:113,661,712...113,668,558
Ensembl chr 3:113,661,004...113,670,418 		JBrowse link
G PON2 paraoxonase 2 ISO protein:increased expression:white adipose tissue RGD PMID:21365757 RGD:8661255 NCBI chr 9:75,027,270...75,051,441
Ensembl chr 9:75,027,097...75,051,422 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha treatment ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:decreased expression:left ventricle myocardium (rat)		 CTD
RGD		 PMID:11089532 PMID:30738174 PMID:33310031 RGD:329955450 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,741...3,364,239 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta ISO CTD Direct Evidence: therapeutic CTD PMID:16168052 PMID:20176998 NCBI chr 7:31,222,533...31,295,221
Ensembl chr 7:31,222,585...31,295,211 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma susceptibility
treatment		 ISO DNA:polymorphism
ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity due to SIM1 deficiency
ClinVar Annotator: match by term: Monogenic Non-Syndromic Obesity | ClinVar Annotator: match by term: Monogenic Obesity | ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity disorder		 OMIM
RGD
ClinVar		 PMID:9467001 PMID:9792554 PMID:10381354 PMID:10523018 PMID:10622252 More... RGD:2301847 RGD:401960083 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha treatment ISO mRNA:increased expression:retroperitoneal fat pad (rat)
mRNA:decreased expression:left ventricle myocardium (rat)		 RGD PMID:22401878 PMID:23180161 PMID:23256146 PMID:33310031 RGD:329955450 RGD:7241848 RGD:7242011 RGD:7242183 NCBI chr 8:17,841,844...18,527,953
Ensembl chr 8:17,841,844...17,946,992 		JBrowse link
G PPARGC1B PPARG coactivator 1 beta resistance ISO DNA:polymorphism: :p.A203P
ClinVar Annotator: match by term: Obesity, variation in		 RGD
ClinVar		 PMID:15863669 RGD:1642501 NCBI chr 2:150,823,338...150,924,871
Ensembl chr 2:150,823,373...150,919,376 		JBrowse link
G PPIA peptidylprolyl isomerase A ISO mRNA:increased expression:blood (human) RGD PMID:32496587 RGD:150383342 NCBI chr18:50,563,130...50,566,857 JBrowse link
G PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L ISO CTD Direct Evidence: marker/mechanism CTD PMID:18344982 NCBI chr13:100,442,445...100,759,968
Ensembl chr13:100,443,011...100,756,039 		JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:29367455 NCBI chr12:11,662,344...11,681,490
Ensembl chr12:11,662,347...11,681,373 		JBrowse link
G PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20975297 NCBI chr 9:106,851,044...106,957,519
Ensembl chr 9:106,851,031...106,957,510 		JBrowse link
G PRKCB protein kinase C beta ISO mRNA, protein:increased expression:mononuclear cell RGD PMID:17180352 RGD:1625512 NCBI chr 3:21,995,227...22,383,628
Ensembl chr 3:21,995,231...22,383,264 		JBrowse link
G PRKCD protein kinase C delta ISO protein:decreased expression:heart ventricle RGD PMID:11478406 RGD:1642533 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,610...35,323,356 		JBrowse link
G PRKCH protein kinase C eta ISO CTD Direct Evidence: marker/mechanism CTD PMID:23563609 NCBI chr 1:190,205,041...190,439,433
Ensembl chr 1:190,206,124...190,439,426 		JBrowse link
G PRKCI protein kinase C iota ISO OMIM:601665 MouseDO NCBI chr13:108,913,018...108,997,934
Ensembl chr13:108,913,173...108,997,931 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO protein:increased expression:kidney, glomerulus RGD PMID:23454089 RGD:7777114 NCBI chr14:97,558,531...98,793,080
Ensembl chr14:97,558,533...98,793,010 		JBrowse link
G PRL prolactin ISO RGD PMID:8388614 RGD:1642559 NCBI chr 7:17,451,367...17,463,771
Ensembl chr 7:17,451,367...17,463,710 		JBrowse link
G PRLH prolactin releasing hormone ISO OMIM:601665 RGD
MouseDO		 PMID:15854142 RGD:1641829 NCBI chr15:137,230,209...137,232,178
Ensembl chr15:137,230,247...137,230,954 		JBrowse link
G PRLHR prolactin releasing hormone receptor ISO RGD PMID:15854142 RGD:1641829 NCBI chr14:128,617,352...128,619,419
Ensembl chr14:128,614,131...128,619,457 		JBrowse link
G PRMT7 protein arginine methyltransferase 7 ISO ClinVar Annotator: match by term: Obesity disorder ClinVar PMID:25741868 PMID:26437029 PMID:27718516 PMID:28492532 PMID:28902392 NCBI chr 6:28,883,148...28,945,904
Ensembl chr 6:28,883,646...28,945,905 		JBrowse link
G PROX1 prospero homeobox 1 ISO OMIM:601665 MouseDO NCBI chr 9:129,527,704...129,583,693
Ensembl chr 9:129,532,184...129,580,982 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver		 CTD
RGD		 PMID:21156398 PMID:21978752 RGD:5508307 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10744717 PMID:20075852 NCBI chr17:52,017,100...52,086,747
Ensembl chr17:52,017,130...52,086,736 		JBrowse link
G PTPRF protein tyrosine phosphatase receptor type F ISO protein:increased expression, increased activity:subcutaneous adipose tissue:2.03-fold higher activity in obese than lean individuals (P < 0.001)
protein:increased expression:skeletal muscle:increased 42% in insulin-resistant obese (fa/fa) and 50% in diabetic (ZDF/Drt-fa/fa) Zucker rats (P<0.05)
protein:increased activity, increased expression:skeletal muscle:activity increased to 140-170% of control in insulin-resistant obese (BMI>30) nondiabetic subjects (p<0.05); activity decreased to 39% in obese NIDDM subjects (p<0.05)		 RGD PMID:7666792 PMID:7769120 PMID:9218523 RGD:1642727 RGD:1642732 RGD:1642733 NCBI chr 6:167,656,674...167,743,750
Ensembl chr 6:167,657,680...167,743,721 		JBrowse link
G PYY peptide YY ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:10898754 PMID:11825645 PMID:16368708 NCBI chr12:19,190,703...19,208,373 JBrowse link
G RAI1 retinoic acid induced 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15459175 PMID:19116176 NCBI chr12:60,751,159...60,854,710
Ensembl chr12:60,755,521...60,766,058 		JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29273807 NCBI chr 5:78,101,286...78,134,150
Ensembl chr 5:78,101,299...78,134,105 		JBrowse link
G RARRES2 retinoic acid receptor responder 2 ISO protein:increased expression:serum: RGD PMID:30873215 PMID:31284705 RGD:15036824 RGD:15036825 NCBI chr18:55,903,693...55,906,976
Ensembl chr18:55,903,699...55,906,945 		JBrowse link
G RB1 RB transcriptional corepressor 1 ISO mRNA:decreased expression:adipose tissue RGD PMID:23315497 RGD:8547988 NCBI chr11:19,186,754...19,317,642
Ensembl chr11:19,186,761...19,317,690 		JBrowse link
G RBP4 retinol binding protein 4 disease_progression
ameliorates		 ISO mRNA, protein:decreased expression:adipose tissue, serum
protein:increased expression:blood serum (human)		 RGD PMID:17292720 PMID:18401839 PMID:21585349 RGD:2302016 RGD:329845862 RGD:329853312 NCBI chr14:105,037,360...105,044,552
Ensembl chr14:105,037,464...105,044,765 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO RGD PMID:18356846 RGD:2298856 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G REN renin ISO mRNA:increased expression:abdomen, subcutaneous adipose tissue, mesenchymal stem cell (human) RGD PMID:22648117 RGD:6784503 NCBI chr 9:64,809,143...64,822,605
Ensembl chr 9:64,809,146...64,822,658 		JBrowse link
G RETN resistin ISO mRNA, protein:increased expression:subcutaneous adipose tissue, serum
DNA:SNP:promoter:-420C>G (human)		 RGD PMID:11201732 PMID:17598818 PMID:22816026 RGD:7207072 RGD:7207155 RGD:7207158 NCBI chr 2:71,484,164...71,485,577
Ensembl chr 2:71,484,169...71,485,616 		JBrowse link
G RHOA ras homolog family member A ISO protein:increased expression:membrane, aorta, skeletal muscle RGD PMID:16267124 RGD:2298881 NCBI chr13:31,918,484...31,991,207
Ensembl chr13:31,918,834...31,986,607 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 ISO protein:increased phosphorylation:skeletal muscle RGD PMID:15604215 RGD:1642978 NCBI chr12:36,111,584...36,159,287
Ensembl chr12:36,111,653...36,160,376 		JBrowse link
G RSC1A1 regulator of solute carriers 1 ISO OMIM:601665 MouseDO NCBI chr 1:268,428,423...268,429,766
NCBI chr 6:74,846,976...74,865,376
Ensembl chr 6:74,809,350...74,855,423 		JBrowse link
G RSRC2 arginine and serine rich coiled-coil 2 ISO ClinVar Annotator: match by term: Obesity ClinVar NCBI chr14:30,242,063...30,261,166
Ensembl chr14:30,242,142...30,261,600 		JBrowse link
G RXRA retinoid X receptor alpha susceptibility ISO RGD PMID:15936932 RGD:1643104 NCBI chr 1:273,698,842...273,797,622
Ensembl chr 1:273,705,505...273,797,620 		JBrowse link
G RYR1 ryanodine receptor 1 ISO ClinVar Annotator: match by term: Obesity disorder ClinVar PMID:25741868 PMID:28492532 NCBI chr 6:47,339,759...47,458,457
Ensembl chr 6:47,343,768...47,458,458 		JBrowse link
G SAT1 spermidine/spermine N1-acetyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr  X:19,908,037...19,910,553
Ensembl chr  X:19,907,906...19,910,974 		JBrowse link
G SCAPER S-phase cyclin A associated protein in the ER ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:25741868 PMID:30723319 NCBI chr 7:56,583,247...57,012,312
Ensembl chr 7:56,583,160...57,011,914 		JBrowse link
G SDC1 syndecan 1 ISO mRNA:increased expression:liver RGD PMID:11522680 RGD:1643129 NCBI chr 3:117,987,585...118,011,886
Ensembl chr 3:117,987,557...118,011,884 		JBrowse link
G SDC3 syndecan 3 ISO ClinVar Annotator: match by term: Obesity, association with OMIM
ClinVar		 PMID:17018662 NCBI chr 6:87,495,041...87,535,689
Ensembl chr 6:87,495,045...87,507,235 		JBrowse link
G SELP selectin P ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:altered localization:platelet RGD PMID:19228864 RGD:2312291 NCBI chr 4:81,376,804...81,401,240
Ensembl chr 4:81,365,740...81,399,955 		JBrowse link
G SERPINE1 serpin family E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23819014 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,547 		JBrowse link
G SERPINF1 serpin family F member 1 ISO protein:increased expression:serum (rat) RGD PMID:17491674 PMID:24424059 RGD:2312347 RGD:8633067 NCBI chr12:47,949,004...47,959,471
Ensembl chr12:47,948,510...47,959,470 		JBrowse link
G SFTPA1 surfactant protein A1 ISO protein:increased expression:lung RGD PMID:15136884 RGD:4143472 NCBI chr14:82,091,178...82,095,393
Ensembl chr14:82,091,178...82,095,393 		JBrowse link
G SFTPB surfactant protein B ISO protein:increased expression:lung RGD PMID:15136884 RGD:4143472 NCBI chr 3:59,101,940...59,113,442
Ensembl chr 3:59,101,981...59,112,396 		JBrowse link
G SH2B1 SH2B adaptor protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19079261 NCBI chr 3:18,533,282...18,543,133
Ensembl chr 3:18,524,820...18,543,135 		JBrowse link
G SIM1 SIM bHLH transcription factor 1 ISO ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity due to SIM1 deficiency | ClinVar Annotator: match by term: SIM1-related condition | ClinVar Annotator: match by term: UCP3-related condition ClinVar PMID:2152513 PMID:16924270 PMID:19401419 PMID:21512513 PMID:23778136 More... NCBI chr 1:67,213,685...67,294,455
Ensembl chr 1:67,214,337...67,294,397 		JBrowse link
G SIRT1 sirtuin 1 treatment ISO protein:decreased expression:ovary
CTD Direct Evidence: therapeutic		 RGD
CTD		 PMID:24135502 PMID:24184811 PMID:24773342 RGD:9585762 RGD:9586064 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297 		JBrowse link
G SIRT3 sirtuin 3 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:21901160 PMID:23956348 RGD:9586047 NCBI chr 2:38,465...55,074
Ensembl chr 2:38,464...55,101 		JBrowse link
G SIRT6 sirtuin 6 ISO protein:decreased expression:ovary RGD PMID:24135502 RGD:9586064 NCBI chr 2:74,568,539...74,577,774
Ensembl chr 2:74,568,493...74,577,772 		JBrowse link
G SLC10A1 solute carrier family 10 member 1 disease_progression ISO mRNA:increased expression:liver (rat) RGD PMID:25612518 RGD:15045599 NCBI chr 7:93,400,037...93,421,989
Ensembl chr 7:93,397,608...93,421,985 		JBrowse link
G SLC16A7 solute carrier family 16 member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr 5:24,713,009...24,871,891
Ensembl chr 5:24,713,267...24,875,003 		JBrowse link
G SLC22A1 solute carrier family 22 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20956498 NCBI chr 1:7,340,442...7,365,543
Ensembl chr 1:7,340,126...7,365,520 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27401566 NCBI chr 1:7,289,278...7,323,418
Ensembl chr 1:7,289,831...7,323,146 		JBrowse link
G SLC22A3 solute carrier family 22 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27401566 NCBI chr 1:7,105,486...7,207,395
Ensembl chr 1:7,110,074...7,207,401 		JBrowse link
G SLC27A1 solute carrier family 27 member 1 susceptibility ISO DNA:gene knockout::Slc27a1-/- mice resistant to diet-induced obesity and metabolic syndrome
protein:increased expression:soleus muscle, protein:decreased expression:gastrocnemius muscle		 RGD PMID:15281014 PMID:16611988 RGD:1642790 RGD:1642794 NCBI chr 2:60,203,374...60,235,689
Ensembl chr 2:60,203,388...60,235,588 		JBrowse link
G SLC27A4 solute carrier family 27 member 4 ISO mRNA:increased expression:subcutaneous adipose tissue RGD PMID:15168018 RGD:1625638 NCBI chr 1:268,773,792...268,788,208
Ensembl chr 1:268,773,806...268,788,731 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 treatment ISO associated with Polycystic Ovary Syndrome RGD PMID:24842895 RGD:12879503 NCBI chr 6:168,535,398...168,561,170
Ensembl chr 6:168,535,440...168,560,867 		JBrowse link
G SLC32A1 solute carrier family 32 member 1 ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:25741868 NCBI chr17:41,689,479...41,694,560
Ensembl chr17:41,689,479...41,694,553 		JBrowse link
G SLC6A1 solute carrier family 6 member 1 ISO RGD PMID:11191352 RGD:1643191 NCBI chr13:67,156,786...67,199,092
Ensembl chr13:67,179,765...67,197,107 		JBrowse link
G SLC6A14 solute carrier family 6 member 14 susceptibility ISO DNA:SNPs RGD PMID:15331564 RGD:1625271 NCBI chr  X:95,482,494...95,507,200
Ensembl chr  X:95,482,456...95,527,369 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 susceptibility
no_association		 ISO DNA:polymorphism RGD PMID:12490667 PMID:16674552 RGD:1625653 RGD:1625655 NCBI chr16:79,186,114...79,220,302
Ensembl chr16:79,186,108...79,220,297 		JBrowse link
G SLC9A3 solute carrier family 9 member A3 ISO protein:decreased expression:kidney cortex RGD PMID:16757903 RGD:1625672 NCBI chr16:79,625,555...79,704,084
Ensembl chr16:79,666,825...79,700,658 		JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:25741868 PMID:28492532 NCBI chr 2:69,717,175...69,810,301
Ensembl chr 2:69,662,238...69,810,295 		JBrowse link
G SNAP25 synaptosome associated protein 25 ISO OMIM:601665 MouseDO NCBI chr17:19,096,115...19,227,580
Ensembl chr17:19,141,464...19,227,576 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO mRNA, protein:increased expression:white fat RGD PMID:11027633 RGD:2298920 NCBI chr 3:31,879,143...31,883,041
Ensembl chr 3:31,881,225...31,884,967 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 ISO mRNA:decreased expression:subcutaneous adipose tissue
mRNA:altered expression:skeletal muscle, subcutaneous adipose tissue
mRNA, protein:increased expression:white fat
DNA:SNP:utr (rs4969170) (human)		 RGD PMID:11027633 PMID:15331532 PMID:16920065 PMID:23900445 RGD:1625676 RGD:2298920 RGD:2313790 RGD:405650675 NCBI chr12:3,643,832...3,647,015
Ensembl chr12:3,643,929...3,647,009 		JBrowse link
G SOD1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24042701 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729 		JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16317704 PMID:23956348 PMID:30738174 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560 		JBrowse link
G SORBS1 sorbin and SH3 domain containing 1 ISO DNA:SNP: :p.T228A (human) RGD PMID:11532984 RGD:1642744 NCBI chr14:106,895,764...107,137,469
Ensembl chr14:106,895,765...107,137,561 		JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO mRNA:increased expression:adipose tissue RGD PMID:11294850 RGD:2300062 NCBI chr16:71,368,164...71,380,972
Ensembl chr16:71,357,586...71,381,161 		JBrowse link
G SQLE squalene epoxidase ISO RGD PMID:15556298 RGD:1581399 NCBI chr 4:14,669,789...14,700,152
Ensembl chr 4:14,669,791...14,700,126 		JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 ISO mRNA:increased expression:liver (rat) RGD PMID:20098742 RGD:4891511 NCBI chr16:75,309,830...75,335,438
Ensembl chr16:75,310,211...75,335,391 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:25741868 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 ISO protein:increased expression:fat cell, nucleus RGD PMID:9786926 RGD:2308843 NCBI chr 5:6,719,484...6,784,724
Ensembl chr 5:6,719,490...6,784,671 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO protein:decreased phosphorylation:hypothalamus
DNA:SNP:rs4796793 (human)		 RGD PMID:23397595 PMID:23900445 RGD:10411893 RGD:405650675 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 treatment ISO RGD PMID:20978234 RGD:5509594 NCBI chr15:95,656,206...95,764,099
Ensembl chr15:95,656,077...95,763,472 		JBrowse link
G STK11 serine/threonine kinase 11 ISO protein:decreased expression:gastrocnemius RGD PMID:16352671 RGD:1601389 NCBI chr 2:77,229,888...77,249,322
Ensembl chr 2:77,230,372...77,249,327 		JBrowse link
G STS steroid sulfatase ISO CTD Direct Evidence: therapeutic CTD PMID:24497646 NCBI chr  X:3,926,027...4,076,900
NCBI chr  Y:2,747,102...2,828,322 		JBrowse link
G SUCLA2 succinate-CoA ligase ADP-forming subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr11:19,616,415...19,670,667
Ensembl chr11:19,616,495...19,670,662 		JBrowse link
G SUCLG2 succinate-CoA ligase GDP-forming subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr13:48,650,851...49,090,521
Ensembl chr13:48,823,733...49,090,468 		JBrowse link
G SZT2 SZT2 subunit of KICSTOR complex ISO ClinVar Annotator: match by term: Obesity ClinVar PMID:25741868 NCBI chr 6:167,811,589...167,861,321
Ensembl chr 6:167,811,598...167,861,583 		JBrowse link
G TBC1D1 TBC1 domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16893906 PMID:18325908 PMID:18931681 NCBI chr 8:29,370,344...29,590,574
Ensembl chr 8:29,370,481...29,590,571 		JBrowse link
G TBX3 T-box transcription factor 3 ISO ClinVar Annotator: match by term: Obesity disorder ClinVar PMID:28492532 NCBI chr14:37,582,704...37,596,767
Ensembl chr14:37,582,822...37,596,766 		JBrowse link
G TBXA2R thromboxane A2 receptor ISO mRNA:increased expression:carotid artery RGD PMID:12409963 RGD:1601447 NCBI chr 2:75,068,413...75,081,305
Ensembl chr 2:75,068,698...75,087,731 		JBrowse link
G TF transferrin ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16267817 PMID:20882379 RGD:1601520 NCBI chr13:74,930,655...74,970,599
Ensembl chr13:74,930,655...74,972,763 		JBrowse link
G TFAM transcription factor A, mitochondrial treatment ISO mRNA:decreased expression:left ventricle myocardium (rat) RGD PMID:21862610 PMID:33310031 RGD:329955450 RGD:5683906 NCBI chr14:92,261,713...92,279,731
Ensembl chr14:92,259,403...92,279,731 		JBrowse link
G TFRC transferrin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17062801 PMID:20882379 NCBI chr13:133,976,765...133,997,554
Ensembl chr13:133,970,985...134,000,276 		JBrowse link
G TGFB1 transforming growth factor beta 1 severity ISO protein:increased expression:adipose tissue
associated with hypertension;protein:increased expression:blood
protein:increased expression:platelet		 RGD PMID:15944724 PMID:16253647 PMID:16477387 RGD:1601561 RGD:1601563 RGD:1601579 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G TH tyrosine hydroxylase resistance ISO DNA:polymorphism:intron:g.1170_1173dupTCAT (human) RGD PMID:16251897 RGD:1601632 NCBI chr 2:1,499,628...1,506,180
Ensembl chr 2:1,499,620...1,506,170 		JBrowse link
G THBD thrombomodulin severity ISO protein:increased expression:plasma RGD PMID:16651309 RGD:1601640 NCBI chr17:30,219,870...30,223,499
Ensembl chr17:30,217,303...30,224,099 		JBrowse link
G THBS1 thrombospondin 1 ISO mRNA,protein:increased expression:mononuclear cell, adipose tissue: RGD PMID:24086512 RGD:9681453 NCBI chr 1:131,728,781...131,746,098
Ensembl chr 1:131,728,784...131,746,115 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 ISO protein:increased expression:plasma RGD PMID:17512313 RGD:1642026 NCBI chr  X:42,103,251...42,106,289
Ensembl chr  X:42,102,172...42,106,296 		JBrowse link
G TLR2 toll like receptor 2 ISO RGD PMID:18787058 RGD:2312681 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330 		JBrowse link
G TLR4 toll like receptor 4 susceptibility ISO RGD PMID:17053832 PMID:19144836 RGD:1620653 RGD:2312510 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G TMEM18 transmembrane protein 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19079261 NCBI chr 3:132,424,108...132,431,682
Ensembl chr 3:132,426,431...132,431,678 		JBrowse link
G TMEM19 transmembrane protein 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29273807 NCBI chr 5:35,757,273...35,788,754
Ensembl chr 5:35,757,494...35,787,654 		JBrowse link
G TNF tumor necrosis factor treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:9502777 PMID:11328671 PMID:20141834 PMID:24146106 PMID:28843383 More... RGD:10450599 RGD:14975146 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO protein:increased expression:serum RGD PMID:12935365 RGD:1624179 NCBI chr 5:64,319,349...64,331,876
Ensembl chr 5:64,319,051...64,331,909 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:11782876 NCBI chr 6:72,195,420...72,231,146
Ensembl chr 6:72,195,435...72,231,147 		JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17347480 NCBI chr12:49,676,536...49,709,634
Ensembl chr12:49,677,291...49,713,977 		JBrowse link
G TSC1 TSC complex subunit 1 ISO DNA:hypermethylation:promoter RGD PMID:25807795 RGD:11570513 NCBI chr 1:272,636,530...272,685,948
Ensembl chr 1:272,636,532...272,685,951 		JBrowse link
G TUB TUB bipartite transcription factor no_association
susceptibility		 ISO DNA:splice-site mutation
OMIM:601665		 RGD
MouseDO		 PMID:8612280 PMID:8772727 RGD:1625564 RGD:1625565 NCBI chr 9:1,183,821...1,260,209
Ensembl chr 9:1,183,822...1,206,274 		JBrowse link
G TYK2 tyrosine kinase 2 ISO OMIM:601665 MouseDO NCBI chr 2:69,157,774...69,183,555
Ensembl chr 2:69,157,811...69,183,456 		JBrowse link
G UCN urocortin treatment ISO RGD PMID:17932219 RGD:1642774 NCBI chr 3:111,834,082...111,835,932
Ensembl chr 3:111,835,125...111,835,508 		JBrowse link
G UCP1 uncoupling protein 1 no_association ISO CTD Direct Evidence: marker/mechanism|therapeutic
DNA:polymorphism: :-3826A>G (human)		 CTD
RGD		 PMID:8968850 PMID:15592485 RGD:1624977 NCBI chr 8:86,522,028...86,526,162 JBrowse link
G UCP2 uncoupling protein 2 susceptibility ISO DNA:SNPs, insertion/deletion, haplotypes:promoter, 3' utr:-2723T>A, -866G>A, *158_159ins45 (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism, insertion:promoter:-866G>A (rs659366)(human)		 RGD
CTD		 PMID:11381268 PMID:17870627 RGD:2313512 RGD:737761 NCBI chr 9:8,358,559...8,364,552
Ensembl chr 9:8,358,025...8,365,547 		JBrowse link
G UCP3 uncoupling protein 3 susceptibility
no_association		 ISO DNA:polymorphism:promoter:-55C>T (human)
DNA:polymorphism:exon (human)
ClinVar Annotator: match by term: Monogenic Non-Syndromic Obesity | ClinVar Annotator: match by term: Monogenic Obesity | ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: UCP3 POLYMORPHISM G/A | ClinVar Annotator: match by term: UCP3-related condition
ClinVar Annotator: match by term: Monogenic Obesity | ClinVar Annotator: match by term: Obesity | ClinVar Annotator: match by term: Obesity disorder | ClinVar Annotator: match by term: UCP3 POLYMORPHISM G/A | ClinVar Annotator: match by term: UCP3-related condition		 OMIM
RGD
ClinVar		 PMID:9700198 PMID:9769326 PMID:10431807 PMID:10480626 PMID:10618503 More... RGD:2313506 RGD:2313526 NCBI chr 9:8,378,023...8,389,452
Ensembl chr 9:8,378,021...8,386,211 		JBrowse link
G ULK4 unc-51 like kinase 4 ISO ClinVar Annotator: match by term: Obesity ClinVar NCBI chr13:25,207,890...25,751,465
Ensembl chr13:25,209,368...25,751,500 		JBrowse link
G UQCRC2 ubiquinol-cytochrome c reductase core protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20882379 NCBI chr 3:24,197,743...24,228,831
Ensembl chr 3:24,197,747...24,228,832 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:19260948 RGD:2312763 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,920...117,511,222 		JBrowse link
G VGF VGF nerve growth factor inducible ISO CTD Direct Evidence: therapeutic CTD PMID:12177191 NCBI chr 3:8,888,502...8,891,399
Ensembl chr 3:8,888,506...8,891,601 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor ISO associated with hepatocellular carcinoma;RNA:decreased expression:liver: RGD PMID:31321740 RGD:155882550 NCBI chr13:66,334,535...66,342,401
Ensembl chr13:66,334,591...66,342,654 		JBrowse link
G VLDLR very low density lipoprotein receptor susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11557677 PMID:20975297 RGD:1625568 NCBI chr 1:219,178,501...219,210,332
Ensembl chr 1:219,173,507...219,210,343 		JBrowse link
G VWF von Willebrand factor ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:plasma RGD PMID:16631442 PMID:16739871 RGD:1625710 RGD:1625711 NCBI chr 5:64,516,627...64,655,938
Ensembl chr 5:64,517,555...64,655,938 		JBrowse link
G WNT10B Wnt family member 10B ISO DNA:SNP:CDS:amino acid C256Y, mutant unable to activate WNT/beta-catenin signaling pathway RGD PMID:16477437 PMID:17578883 RGD:2300029 RGD:2326237 NCBI chr 5:14,997,377...15,013,928
Ensembl chr 5:14,997,381...15,003,567 		JBrowse link
G WNT3A Wnt family member 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28242765 NCBI chr 2:51,153,978...51,203,678
Ensembl chr 2:51,153,970...51,202,176 		JBrowse link
G XDH xanthine dehydrogenase treatment ISO RGD PMID:7616299 RGD:13210504 NCBI chr 3:107,987,060...108,052,043
Ensembl chr 3:107,987,126...108,053,169 		JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29273807 NCBI chr 4:94,780,404...94,796,722
Ensembl chr 4:94,780,408...94,796,657 		JBrowse link
G ZC3H10 zinc finger CCCH-type containing 10 ISO CTD Direct Evidence: therapeutic CTD PMID:31775033 NCBI chr 5:21,506,510...21,513,972
Ensembl chr 5:21,508,218...21,514,590 		JBrowse link
G ZFHX3 zinc finger homeobox 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29273807 NCBI chr 6:15,693,987...15,941,301
Ensembl chr 6:15,698,199...15,863,270 		JBrowse link
G ZFR2 zinc finger RNA binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29273807 NCBI chr 2:74,845,912...74,899,121
Ensembl chr 2:74,845,921...74,900,054 		JBrowse link
G ZNF169 zinc finger protein 169 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29273807 NCBI chr 3:43,503,225...43,561,299
Ensembl chr 3:43,504,685...43,558,908 		JBrowse link
Abdominal Obesity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD163 CD163 molecule exacerbates ISO protein:increased expression:blood serum (human) RGD PMID:31027316 RGD:127345132 NCBI chr 5:63,300,200...63,334,497
Ensembl chr 5:63,300,231...63,334,498 		JBrowse link
G CYP2R1 cytochrome P450 family 2 subfamily R member 1 ISO DNA:SNP:CDS: rs12794714 (human) RGD PMID:34906413 RGD:401900724 NCBI chr 2:44,375,432...44,394,122
Ensembl chr 2:44,375,520...44,396,334 		JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15199296 NCBI chr 9:133,231,451...133,278,396
Ensembl chr 9:133,231,451...133,278,396 		JBrowse link
abdominal obesity-metabolic syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTF1 cardiotrophin 1 ISO MouseDO NCBI chr 3:17,539,927...17,545,250
Ensembl chr 3:17,539,941...17,544,396 		JBrowse link
G LEP leptin ISO MouseDO NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,323 		JBrowse link
G NEIL1 nei like DNA glycosylase 1 ISO MouseDO NCBI chr 7:58,261,761...58,269,001
Ensembl chr 7:58,261,769...58,268,522 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15309680 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,741...3,364,239 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO MouseDO NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO mRNA:increased expression:gastrocnemius muscle (rat) RGD PMID:23320128 RGD:7241841 NCBI chr 8:17,841,844...18,527,953
Ensembl chr 8:17,841,844...17,946,992 		JBrowse link
G PRKCI protein kinase C iota ISO MouseDO NCBI chr13:108,913,018...108,997,934
Ensembl chr13:108,913,173...108,997,931 		JBrowse link
G SIRT3 sirtuin 3 ISO MouseDO NCBI chr 2:38,465...55,074
Ensembl chr 2:38,464...55,101 		JBrowse link
G SLC2A9 solute carrier family 2 member 9 ISO MouseDO NCBI chr 8:6,211,143...6,367,530
Ensembl chr 8:6,210,478...6,367,496 		JBrowse link
abdominal obesity-metabolic syndrome 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO protein:increased oxidation:cardiac muscle cell RGD PMID:23997093 RGD:13782087 NCBI chr14:31,674,659...31,744,981
Ensembl chr14:31,674,757...31,744,969 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:27131981 RGD:13792503 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147 		JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:27131981 RGD:13792503 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G FADD Fas associated via death domain treatment ISO RGD PMID:27131981 RGD:13792503 NCBI chr 2:3,191,718...3,194,820
Ensembl chr 2:3,185,675...3,194,818 		JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:30172001 RGD:13792561 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716 		JBrowse link
G LEP leptin ISO OMIM:605552 MouseDO NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,323 		JBrowse link
G LPL lipoprotein lipase treatment ISO RGD PMID:26996629 RGD:13794382 NCBI chr14:4,104,761...4,134,964
Ensembl chr14:4,104,772...4,135,814 		JBrowse link
G MTTP microsomal triglyceride transfer protein ISO ClinVar Annotator: match by term: Abdominal obesity-metabolic syndrome 1 ClinVar PMID:8533758 PMID:9671739 PMID:16199547 PMID:16721486 PMID:21394827 More... NCBI chr 8:120,820,660...120,871,468
Ensembl chr 8:120,820,656...120,879,388 		JBrowse link
G TLR2 toll like receptor 2 susceptibility ISO RGD PMID:19841034 RGD:15090861 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330 		JBrowse link
G TP53INP1 tumor protein p53 inducible nuclear protein 1 ISO OMIM:605552 MouseDO NCBI chr 4:41,747,654...41,766,688
Ensembl chr 4:41,747,654...41,766,685 		JBrowse link
abdominal obesity-metabolic syndrome 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHDC1 AT-hook DNA binding motif containing 1 ISO ClinVar Annotator: match by term: Abdominal obesity-metabolic syndrome 3 ClinVar PMID:25741868 PMID:29696776 PMID:33644933 NCBI chr 6:84,735,253...84,774,554
Ensembl chr 6:84,735,253...84,802,456 		JBrowse link
G DYRK1B dual specificity tyrosine phosphorylation regulated kinase 1B ISO ClinVar Annotator: match by term: Abdominal obesity-metabolic syndrome 3 | ClinVar Annotator: match by term: CENTRAL OBESITY, TYPE 2 DIABETES, HYPERTENSION, AND EARLY-ONSET CORONARY ARTERY DISEASE | ClinVar Annotator: match by term: DYRK1B-related condition OMIM
ClinVar		 PMID:9536098 PMID:17576681 PMID:24827035 PMID:25741868 PMID:28492532 More... NCBI chr 6:48,305,837...48,314,523
Ensembl chr 6:48,305,849...48,314,514 		JBrowse link
Borjeson-Forssman-Lehmann syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PHF6 PHD finger protein 6 ISO ClinVar Annotator: match by term: Borjeson-Forssman-Lehmann syndrome | ClinVar Annotator: match by term: MENTAL RETARDATION, X-LINKED, SYNDROMIC, BORJESON-FORSSMAN-LEHMANN TYPE | ClinVar Annotator: match by term: Mental deficiency, epilepsy and endocrine disorders OMIM
ClinVar		 PMID:12415272 PMID:13871358 PMID:15241480 PMID:15466013 PMID:15580208 More... NCBI chr  X:110,249,010...110,311,503
Ensembl chr  X:110,249,010...110,303,017 		JBrowse link
CHOPS Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFF4 ALF transcription elongation factor 4 ISO ClinVar Annotator: match by term: AFF4-related condition | ClinVar Annotator: match by term: Cognitive impairment - coarse facies - heart defects - obesity - pulmonary involvement - short stature - skeletal dysplasia syndrome OMIM
ClinVar		 PMID:9536098 PMID:17576681 PMID:25730767 PMID:25741868 PMID:28492532 More... NCBI chr 2:135,196,067...135,283,931
Ensembl chr 2:135,200,076...135,283,675 		JBrowse link
Clark-Baraitser syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRIP12 thyroid hormone receptor interactor 12 ISO ClinVar Annotator: match by term: Clark-Baraitser syndrome | ClinVar Annotator: match by term: TRIP12-related condition OMIM
ClinVar		 PMID:3812552 PMID:25363768 PMID:25741868 PMID:27848077 PMID:28251352 More... NCBI chr15:130,784,567...130,940,497
Ensembl chr15:130,787,864...130,939,783 		JBrowse link
Cohen syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD46 ankyrin repeat domain 46 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:36,400,610...36,445,590
Ensembl chr 4:36,400,660...36,444,335 		JBrowse link
G ATP6V1C1 ATPase H+ transporting V1 subunit C1 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:34,033,943...34,084,990
Ensembl chr 4:34,029,295...34,222,405 		JBrowse link
G AZIN1 antizyme inhibitor 1 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:34,221,368...34,257,261
Ensembl chr 4:34,234,679...34,257,134 		JBrowse link
G BAALC BAALC binder of MAP3K1 and KLF4 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:33,894,240...33,983,920
Ensembl chr 4:33,892,079...33,984,121 		JBrowse link
G COX6C COX6C protein ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:37,074,619...37,089,364
Ensembl chr 4:37,074,649...37,091,849 		JBrowse link
G CTHRC1 collagen triple helix repeat containing 1 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:33,759,541...33,771,625
Ensembl chr 4:33,759,542...33,771,582 		JBrowse link
G DCAF13 DDB1 and CUL4 associated factor 13 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:33,672,867...33,704,888
Ensembl chr 4:33,672,871...33,704,573 		JBrowse link
G DCSTAMP dendrocyte expressed seven transmembrane protein ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:32,912,320...32,928,323
Ensembl chr 4:32,913,152...32,928,235 		JBrowse link
G DPYS dihydropyrimidinase ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:32,791,152...32,879,489
Ensembl chr 4:32,789,460...32,879,489 		JBrowse link
G FZD6 frizzled class receptor 6 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:33,811,159...33,844,556
Ensembl chr 4:33,809,809...33,844,656 		JBrowse link
G GRHL2 grainyhead like transcription factor 2 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:35,368,788...35,565,394
Ensembl chr 4:35,371,136...35,564,919 		JBrowse link
G KCNS2 potassium voltage-gated channel modifier subfamily S member 2 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:15141358 PMID:16648375 PMID:20461111 PMID:28492532 NCBI chr 4:38,362,882...38,374,415
Ensembl chr 4:38,361,347...38,367,695 		JBrowse link
G KLF10 KLF transcription factor 10 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:34,430,132...34,435,990
Ensembl chr 4:34,429,941...34,436,004 		JBrowse link
G LRP12 LDL receptor related protein 12 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:32,701,830...32,783,391
Ensembl chr 4:32,701,835...32,783,390 		JBrowse link
G MYO7A myosin VIIA ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:9382091 PMID:24033266 PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr 9:11,251,187...11,337,618
Ensembl chr 9:11,249,075...11,666,296 		JBrowse link
G NCALD neurocalcin delta ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:34,924,261...35,369,393
Ensembl chr 4:35,186,182...35,367,412 		JBrowse link
G NIPAL2 NIPA like domain containing 2 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:38,491,029...38,576,606
Ensembl chr 4:38,491,285...38,574,255 		JBrowse link
G ODF1 outer dense fiber of sperm tails 1 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:34,511,077...34,520,601
Ensembl chr 4:34,511,077...34,520,609 		JBrowse link
G OSR2 odd-skipped related transciption factor 2 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:15141358 PMID:16648375 PMID:20461111 PMID:28492532 NCBI chr 4:37,890,200...37,897,935
Ensembl chr 4:37,890,203...37,897,929 		JBrowse link
G PABPC1 poly(A) binding protein cytoplasmic 1 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:36,137,644...36,228,075
Ensembl chr 4:36,209,164...36,228,073 		JBrowse link
G POLR2K RNA polymerase II, I and III subunit K ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:36,849,729...36,852,622
Ensembl chr 4:36,845,242...36,852,610 		JBrowse link
G POP1 POP1 homolog, ribonuclease P/MRP subunit ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:38,608,536...38,656,204
Ensembl chr 4:38,607,708...38,656,151 		JBrowse link
G RGS22 regulator of G protein signaling 22 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:36,856,662...36,872,753
Ensembl chr 4:36,856,937...36,871,618 		JBrowse link
G RGS22 regulator of G protein signaling 22 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:36,883,805...37,042,885
Ensembl chr 4:36,886,588...37,041,502 		JBrowse link
G RIMS2 regulating synaptic membrane exocytosis 2 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:32,999,615...33,613,413
Ensembl chr 4:32,999,618...33,614,366 		JBrowse link
G RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:36,654,197...36,727,514
Ensembl chr 4:36,635,285...36,725,638 		JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:34,823,869...34,859,777
Ensembl chr 4:34,823,758...34,859,778 		JBrowse link
G SLC25A32 solute carrier family 25 member 32 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:33,704,810...33,727,796
Ensembl chr 4:33,704,771...33,730,130 		JBrowse link
G SNX31 sorting nexin 31 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:36,303,313...36,390,214
Ensembl chr 4:36,303,284...36,388,952 		JBrowse link
G SPAG1 sperm associated antigen 1 ISO ClinVar Annotator: match by term: Cohen syndrome | ClinVar Annotator: match by term: VPS13B-related condition ClinVar PMID:25741868 PMID:28492532 NCBI chr 4:36,746,798...36,844,662
Ensembl chr 4:36,746,801...36,844,512 		JBrowse link
G STK3 serine/threonine kinase 3 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:15141358 PMID:16648375 PMID:20461111 PMID:28492532 NCBI chr 4:38,011,802...38,306,777
Ensembl chr 4:38,011,814...38,306,773 		JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:34,645,794...34,794,510
Ensembl chr 4:34,645,809...34,793,940 		JBrowse link
G VPS13B vacuolar protein sorting 13 homolog B ISO ClinVar Annotator: match by term: Cohen syndrome | ClinVar Annotator: match by term: Pepper syndrome | ClinVar Annotator: match by term: VPS13B-related condition OMIM
ClinVar		 PMID:9536098 PMID:11169562 PMID:12730828 PMID:15141358 PMID:15154116 More... NCBI chr 4:37,085,929...37,821,159
Ensembl chr 4:37,090,936...37,820,419 		JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:35,975,513...36,009,909
Ensembl chr 4:35,975,508...36,009,887 		JBrowse link
G ZFPM2 zinc finger protein, FOG family member 2 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:31,607,968...31,996,226
Ensembl chr 4:31,606,773...32,094,287 		JBrowse link
G ZNF706 zinc finger protein 706 ISO ClinVar Annotator: match by term: Cohen syndrome ClinVar PMID:28492532 NCBI chr 4:35,768,087...35,777,048
Ensembl chr 4:35,768,190...35,774,386 		JBrowse link
congenital leptin deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LEP leptin ISO ClinVar Annotator: match by term: LEP-related condition | ClinVar Annotator: match by term: Leptin dysfunction | ClinVar Annotator: match by term: Obesity due to congenital leptin deficiency OMIM
ClinVar		 PMID:9202122 PMID:9500540 PMID:9745435 PMID:12393845 PMID:15070752 More... NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,323 		JBrowse link
G LEPR leptin receptor ISO ClinVar Annotator: match by term: Obesity due to congenital leptin deficiency ClinVar PMID:25741868 NCBI chr 6:146,802,297...146,896,152
Ensembl chr 6:146,801,954...146,895,995 		JBrowse link
DEVELOPMENTAL DELAY, INTELLECTUAL DISABILITY, OBESITY, AND DYSMORPHIC FEATURES term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRAK1BP1 interleukin 1 receptor associated kinase 1 binding protein 1 ISO ClinVar Annotator: match by term: DEVELOPMENTAL DELAY, INTELLECTUAL DISABILITY, OBESITY, AND DYSMORPHISM | ClinVar Annotator: match by term: PHIP-related disorder ClinVar PMID:9536098 PMID:17576681 PMID:23033978 PMID:25741868 PMID:28492532 More... NCBI chr 1:87,289,964...87,329,926
Ensembl chr 1:87,290,826...87,329,716 		JBrowse link
G PHIP pleckstrin homology domain interacting protein ISO ClinVar Annotator: match by term: DEVELOPMENTAL DELAY, INTELLECTUAL DISABILITY, OBESITY, AND DYSMORPHISM | ClinVar Annotator: match by term: PHIP-related disorder OMIM
ClinVar		 PMID:9536098 PMID:16199547 PMID:17576681 PMID:23033978 PMID:25741868 More... NCBI chr 1:87,116,884...87,247,500
Ensembl chr 1:87,117,092...87,243,675 		JBrowse link
Leptin Receptor Deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LEPR leptin receptor ISO ClinVar Annotator: match by term: LEPR-related condition | ClinVar Annotator: match by term: Leptin receptor deficiency OMIM
ClinVar		 PMID:8666155 PMID:9144432 PMID:9537324 PMID:9860295 PMID:11354636 More... NCBI chr 6:146,802,297...146,896,152
Ensembl chr 6:146,801,954...146,895,995 		JBrowse link
G LEPROT leptin receptor overlapping transcript ISO ClinVar Annotator: match by term: Leptin receptor deficiency ClinVar PMID:25741868 PMID:28492532 NCBI chr 6:146,974,641...146,987,261
Ensembl chr 6:146,974,639...146,987,242 		JBrowse link
MEHMO syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2S3 eukaryotic translation initiation factor 2 subunit gamma ISO ClinVar Annotator: match by term: MEHMO syndrome OMIM
ClinVar		 PMID:23063529 PMID:25741868 PMID:25741869 PMID:27333055 PMID:28055140 More... NCBI chr  X:20,129,708...20,162,881
Ensembl chr  X:20,146,933...20,162,702 		JBrowse link
morbid obesity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSS2 acyl-CoA synthetase short chain family member 2 treatment ISO RGD PMID:22384010 RGD:13831306 NCBI chr17:38,260,152...38,315,764
Ensembl chr17:38,260,147...38,315,757 		JBrowse link
G ADCY3 adenylate cyclase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29311637 NCBI chr 3:113,875,005...113,969,053
Ensembl chr 3:113,876,339...113,982,369 		JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment ISO RGD PMID:22828946 RGD:7243249 NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,120...24,221,162 		JBrowse link
G APLN apelin ISO protein:increased expression:plasma
associated with Diabetes Mellitus, Non-Insulin-Dependent		 RGD PMID:15970339 PMID:19756893 RGD:1600932 RGD:2313938 NCBI chr  X:106,236,746...106,246,563
Ensembl chr  X:106,236,749...106,246,377 		JBrowse link
G AQP7 aquaporin 7 ISO mRNA:decreased expression:subcutaneous adipose tissue RGD PMID:17566090 RGD:1626289 NCBI chr10:33,098,746...33,130,245 JBrowse link
G BBS4 Bardet-Biedl syndrome 4 susceptibility ISO DNA:SNPs RGD PMID:17003356 RGD:1601311 NCBI chr 7:60,631,913...60,693,359
Ensembl chr 7:60,631,914...60,693,334 		JBrowse link
G BDNF brain derived neurotrophic factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21708048 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,624,048...32,679,765 		JBrowse link
G CCK cholecystokinin ISO protein:decreased expression:plasma:associated with Metabolic Syndrome X (MeSH:D024821) RGD PMID:17443025 RGD:1625798 NCBI chr13:25,940,674...25,945,879
Ensembl chr13:25,937,645...25,945,793 		JBrowse link
G CPE carboxypeptidase E ISO mRNA:increased expression:visceral abdominal fat:significantly higher expression in visceral fat than subcutaneous fat of morbidly obese subjects RGD PMID:12530526 RGD:1626182 NCBI chr 8:43,568,744...43,695,475
Ensembl chr 8:43,565,054...43,696,268 		JBrowse link
G CTNNBL1 catenin beta like 1 susceptibility
no_association		 ISO DNA:snps:introns:IVS7+3134G>T, IVS7-79A>G (rs6013029, rs6020846) (human) RGD PMID:19228371 PMID:19245693 RGD:9850251 RGD:9850253 NCBI chr17:40,809,932...40,948,844
Ensembl chr17:40,774,720...40,949,022 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO protein:increased activity::3x higher activity in morbidly obese subjects compared to non-obese, activity decreased proportionally with weight loss, activity measured as total oral chlorzoxazone clearance RGD PMID:12883487 RGD:1626305 NCBI chr14:141,690,737...141,703,078
Ensembl chr14:141,690,426...141,736,817 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO RGD PMID:19188925 RGD:2313745 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO mRNA:increased expression:subcutaneous adipose tissue RGD PMID:16046292 RGD:1626320 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO protein:increased expression:serum RGD PMID:11889184 RGD:1626666
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21708048 NCBI chr14:79,345,382...80,106,337
Ensembl chr14:79,352,005...80,106,295 		JBrowse link
G KSR2 kinase suppressor of ras 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29273807 NCBI chr14:34,675,349...35,090,007
Ensembl chr14:34,676,164...35,089,997 		JBrowse link
G LEP leptin ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:9500540 PMID:15070752 NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,323 		JBrowse link
G LEPR leptin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9537324 NCBI chr 6:146,802,297...146,896,152
Ensembl chr 6:146,801,954...146,895,995 		JBrowse link
G LPIN1 lipin 1 ISO RGD PMID:17563064 RGD:1641822 NCBI chr 3:124,940,557...125,074,137
Ensembl chr 3:124,940,561...125,074,122 		JBrowse link
G MC4R melanocortin 4 receptor ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:11443223 PMID:12588803 PMID:29273807 PMID:29311635 RGD:1600750 RGD:1600755 NCBI chr 1:160,772,013...160,774,124
Ensembl chr 1:160,772,013...160,774,124 		JBrowse link
G MCHR1 melanin concentrating hormone receptor 1 onset ISO DNA:SNP:promoter RGD PMID:16186414 RGD:1624359 NCBI chr 5:7,735,752...7,752,006
Ensembl chr 5:7,735,825...7,738,701 		JBrowse link
G NPPB natriuretic peptide B ISO protein:increased expression:serum RGD PMID:17273651 RGD:1642195 NCBI chr 6:71,930,374...71,931,843
Ensembl chr 6:71,930,382...71,932,254 		JBrowse link
G NPY2R neuropeptide Y receptor Y2 ISO DNA:SNP:CDS:NCBI refSNP IDs=rs1047214, rs2880415 coding for silent Ile variants; Pima Indians, males only RGD PMID:15855352 RGD:1642381 NCBI chr 8:74,039,959...74,048,398
Ensembl chr 8:74,039,616...74,047,817 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 onset ISO protein:substitution:Y722C;severe early-onset RGD PMID:16702999 RGD:1626135 NCBI chr10:30,030,050...30,429,938
Ensembl chr10:30,033,405...30,429,882 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO ClinVar Annotator: match by term: Morbid obesity ClinVar PMID:9753710 PMID:10690291 PMID:25157153 PMID:28492532 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944 		JBrowse link
G UCP3 uncoupling protein 3 ISO ClinVar Annotator: match by term: OBESITY, SEVERE ClinVar PMID:9769326 PMID:25741868 PMID:28492532 NCBI chr 9:8,378,023...8,389,452
Ensembl chr 9:8,378,021...8,386,211 		JBrowse link
Morbid Obesity and Spermatogenic Failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEP19 centrosomal protein 19 ISO ClinVar Annotator: match by term: Morbid obesity and spermatogenic failure OMIM
ClinVar		 PMID:24268657 PMID:25741868 PMID:28492532 NCBI chr13:133,420,017...133,428,394
Ensembl chr13:133,420,032...133,428,390 		JBrowse link
MORM Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INPP5E inositol polyphosphate-5-phosphatase E ISO ClinVar Annotator: match by term: INPP5E-related condition | ClinVar Annotator: match by term: MORM syndrome OMIM
ClinVar		 PMID:9536098 PMID:15786477 PMID:17576681 PMID:19668215 PMID:19668216 More...
Obesity and Hypopigmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHCY adenosylhomocysteinase ISO ClinVar Annotator: match by term: Obesity and hypopigmentation ClinVar PMID:36536132 NCBI chr17:37,726,084...37,744,378
Ensembl chr17:37,726,084...37,744,461 		JBrowse link
G ASIP agouti signaling protein ISO ClinVar Annotator: match by term: Obesity and hypopigmentation ClinVar PMID:36536132 NCBI chr17:37,542,615...37,718,787
Ensembl chr17:37,545,474...37,718,779 		JBrowse link
G ITCH itchy E3 ubiquitin protein ligase ISO ClinVar Annotator: match by term: Obesity and hypopigmentation ClinVar PMID:36536132 NCBI chr17:37,810,113...37,918,963
Ensembl chr17:37,810,235...37,918,209 		JBrowse link
Obesity, Hyperphagia, and Developmental Delay term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: NTRK2-related condition | ClinVar Annotator: match by term: Obesity, hyperphagia, and developmental delay OMIM
ClinVar		 PMID:9536098 PMID:15494731 PMID:17576681 PMID:25741868 PMID:27884935 More... NCBI chr10:30,030,050...30,429,938
Ensembl chr10:30,033,405...30,429,882 		JBrowse link
Pediatric Obesity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25137265 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,392...44,218,713 		JBrowse link
G APOA5 apolipoprotein A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25137265 NCBI chr 9:44,177,834...44,180,880
Ensembl chr 9:44,178,606...44,180,885 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase treatment ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs17817449 (human)		 CTD
RGD		 PMID:25137265 PMID:26849546 RGD:11054066 NCBI chr 6:31,177,112...31,564,674
Ensembl chr 6:31,174,569...31,564,718 		JBrowse link
G GPR17 G protein-coupled receptor 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34144038 NCBI chr15:59,692,992...59,702,513
Ensembl chr15:59,692,996...59,701,265 		JBrowse link
G RBP4 retinol binding protein 4 ISO protein:increased expression:blood plasma (human) RGD PMID:25356519 RGD:329853302 NCBI chr14:105,037,360...105,044,552
Ensembl chr14:105,037,464...105,044,765 		JBrowse link
Prader-Willi syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP10A ATPase phospholipid transporting 10A (putative) ISO ClinVar Annotator: match by term: Prader-Willi syndrome ClinVar PMID:28631899 NCBI chr 1:141,493,551...141,667,346
Ensembl chr 1:141,570,493...141,667,338 		JBrowse link
G GABRA5 gamma-aminobutyric acid type A receptor subunit alpha5 ISO ClinVar Annotator: match by term: Prader-Willi syndrome ClinVar PMID:28631899 NCBI chr 1:140,486,107...140,568,204
Ensembl chr 1:140,486,104...140,567,894 		JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 ISO ClinVar Annotator: match by term: Prader-Willi syndrome ClinVar PMID:28631899 NCBI chr 1:140,566,443...140,906,516
Ensembl chr 1:140,566,540...140,905,623 		JBrowse link
G GABRG3 gamma-aminobutyric acid type A receptor subunit gamma3 ISO ClinVar Annotator: match by term: Prader-Willi syndrome ClinVar PMID:28631899 NCBI chr 1:139,855,461...140,464,592
Ensembl chr 1:139,857,095...140,464,579 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO RGD PMID:15057669 RGD:12905043 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917 		JBrowse link
G HCRT hypocretin neuropeptide precursor ISO protein:decreased expression:cerebrospinal fluid RGD PMID:15613151 RGD:1600935 NCBI chr12:20,588,597...20,589,991
Ensembl chr12:20,588,027...20,589,988 		JBrowse link
G HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 ISO ClinVar Annotator: match by term: Prader-Willi syndrome ClinVar PMID:25741868 PMID:28492532 PMID:28631899 NCBI chr15:56,438,117...56,649,805
Ensembl chr15:56,438,148...56,649,792 		JBrowse link
G HTR2C 5-hydroxytryptamine receptor 2C ISO OMIM:176270 MouseDO NCBI chr  X:94,053,415...94,313,352
Ensembl chr  X:94,053,456...94,313,355 		JBrowse link
G MAGEL2 MAGE family member L2 ISO ClinVar Annotator: match by term: Prader-Willi syndrome ClinVar PMID:25741868 PMID:27195816 PMID:28281571 PMID:28492532 PMID:28631899 NCBI chr 1:142,450,414...142,454,633
Ensembl chr 1:142,448,689...142,454,697 		JBrowse link
G MKRN3 makorin ring finger protein 3 ISO ClinVar Annotator: match by term: Prader-Willi syndrome ClinVar PMID:28631899 NCBI chr 1:142,492,089...142,500,968
Ensembl chr 1:142,496,735...142,500,982 		JBrowse link
G NDN necdin, MAGE family member ISO ClinVar Annotator: match by term: Prader-Willi syndrome ClinVar PMID:25741868 PMID:28631899 NCBI chr 1:142,412,688...142,413,665
Ensembl chr 1:142,412,565...142,414,240 		JBrowse link
G NPAP1 nuclear pore associated protein 1 ISO ClinVar Annotator: match by term: Prader-Willi syndrome ClinVar PMID:25741868 PMID:28492532 PMID:28631899 NCBI chr 1:233,074,862...233,080,760 JBrowse link
G OCA2 OCA2 melanosomal transmembrane protein ISO ClinVar Annotator: match by term: Prader-Willi syndrome ClinVar PMID:28631899 NCBI chr15:56,657,648...56,869,920
Ensembl chr15:56,657,616...56,869,918 		JBrowse link
G SNRPN small nuclear ribonucleoprotein polypeptide N susceptibility ISO DNA:deletion
ClinVar Annotator: match by term: Prader-Willi syndrome		 RGD
ClinVar		 PMID:8723064 PMID:28631899 RGD:1601354
G SNURF SNRPN upstream open reading frame ISO ClinVar Annotator: match by term: Prader-Willi syndrome ClinVar PMID:28631899
G UBE3A ubiquitin protein ligase E3A ISO ClinVar Annotator: match by term: Prader-Willi syndrome ClinVar PMID:28631899 NCBI chr 1:141,887,179...142,001,595
Ensembl chr 1:141,887,227...141,995,003 		JBrowse link
Proopiomelanocortin Deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POMC proopiomelanocortin ISO ClinVar Annotator: match by term: Obesity, adrenal insufficiency, and red hair due to POMC deficiency | ClinVar Annotator: match by term: POMC-related condition | ClinVar Annotator: match by term: Proopiomelanocortin deficiency ClinVar
OMIM		 PMID:8302318 PMID:9620771 PMID:9768693 PMID:10193875 PMID:11941477 More... NCBI chr 3:113,661,712...113,668,558
Ensembl chr 3:113,661,004...113,670,418 		JBrowse link
proprotein convertase 1/3 deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAST calpastatin ISO ClinVar Annotator: match by term: OBESITY AND ENDOCRINOPATHY DUE TO IMPAIRED PROCESSING OF PROHORMONES | ClinVar Annotator: match by term: Obesity due to prohormone convertase I deficiency | ClinVar Annotator: match by term: PCSK1-related condition | ClinVar Annotator: match by term: Proprotein convertase 1/3 deficiency ClinVar PMID:9207799 PMID:14617756 PMID:16199547 PMID:17595246 PMID:22210313 More... NCBI chr 2:103,255,738...103,378,623
Ensembl chr 2:103,255,750...103,378,623 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 susceptibility ISO ClinVar Annotator: match by term: OBESITY AND ENDOCRINOPATHY DUE TO IMPAIRED PROCESSING OF PROHORMONES | ClinVar Annotator: match by term: Obesity due to prohormone convertase I deficiency | ClinVar Annotator: match by term: PCSK1-related condition | ClinVar Annotator: match by term: Proprotein convertase 1/3 deficiency ClinVar
OMIM		 PMID:9207799 PMID:14617756 PMID:16199547 PMID:17595246 PMID:22210313 More... NCBI chr 2:103,004,794...103,050,707
Ensembl chr 2:103,004,794...103,050,839 		JBrowse link
Retinal Dystrophy and Obesity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RIC3 RIC3 acetylcholine receptor chaperone ISO ClinVar Annotator: match by term: Retinal dystrophy and obesity | ClinVar Annotator: match by term: TUB-related condition ClinVar PMID:9536098 PMID:16199547 PMID:17576681 PMID:24375934 PMID:25741868 More... NCBI chr 9:1,134,915...1,183,873
Ensembl chr 9:1,134,923...1,181,273 		JBrowse link
G TUB TUB bipartite transcription factor ISO ClinVar Annotator: match by term: Retinal dystrophy and obesity | ClinVar Annotator: match by term: TUB-related condition OMIM
ClinVar		 PMID:9536098 PMID:16199547 PMID:17576681 PMID:24375934 PMID:25741868 More... NCBI chr 9:1,183,821...1,260,209
Ensembl chr 9:1,183,822...1,206,274 		JBrowse link
Schaaf-Yang syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYFIP1 cytoplasmic FMR1 interacting protein 1 ISO associated with Fragile X Syndrome;mRNA:decreased expression:leukocyte (human) RGD PMID:17435464 RGD:11558012 NCBI chr15:32,064,431...32,175,095
Ensembl chr15:32,064,428...32,175,094 		JBrowse link
G MAGEL2 MAGE family member L2 ISO ClinVar Annotator: match by term: MAGEL2-related condition | ClinVar Annotator: match by term: Schaaf-Yang syndrome OMIM
ClinVar		 PMID:24076603 PMID:24088041 PMID:25326635 PMID:25473036 PMID:25590979 More... NCBI chr 1:142,450,414...142,454,633
Ensembl chr 1:142,448,689...142,454,697 		JBrowse link
G SIM1 SIM bHLH transcription factor 1 ISO ClinVar Annotator: match by term: Schaaf-Yang syndrome ClinVar NCBI chr 1:67,213,685...67,294,455
Ensembl chr 1:67,214,337...67,294,397 		JBrowse link
SPASTIC PARAPLEGIA, INTELLECTUAL DISABILITY, NYSTAGMUS, AND OBESITY term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIDINS220 kinase D interacting substrate 220 ISO ClinVar Annotator: match by term: Spastic paraplegia, intellectual disability, nystagmus, and obesity OMIM
ClinVar		 PMID:9536098 PMID:17576681 PMID:25741868 PMID:27005418 PMID:28492532 More... NCBI chr 3:127,382,587...127,477,753
Ensembl chr 3:127,382,611...127,474,195 		JBrowse link
Wilson-Turner syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC8 histone deacetylase 8 ISO DNA:snp:intron:c.164+5G>A (human) RGD PMID:22889856 RGD:13208817 NCBI chr  X:58,210,182...58,450,681
Ensembl chr  X:58,210,192...58,450,573 		JBrowse link
G LAS1L LAS1 like ribosome biogenesis factor ISO ClinVar Annotator: match by term: Wilson-Turner syndrome OMIM
ClinVar		 PMID:1746601 PMID:24647030 PMID:25644381 PMID:25741868 PMID:28492532 NCBI chr  X:51,753,600...51,773,416
Ensembl chr  X:51,741,965...51,773,411 		JBrowse link
G ZC3H12B zinc finger CCCH-type containing 12B ISO ClinVar Annotator: match by term: Wilson-Turner syndrome ClinVar NCBI chr  X:51,231,526...51,749,627
Ensembl chr  X:51,502,732...51,749,625 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15394
    Nutritional and Metabolic Diseases 7361
      nutrition disease 810
        overnutrition 601
          obesity 601
            Abdominal Obesity + 23
            Ayazi Syndrome 0
            Biemond Syndrome II 0
            Borjeson-Forssman-Lehmann syndrome 1
            CHOPS Syndrome 1
            Camera Marugo Cohen Syndrome 0
            Clark-Baraitser syndrome 1
            Cohen syndrome 36
            Coloboma-Obesity-Hypogenitalism-Mental Retardation Syndrome 0
            DEVELOPMENTAL DELAY, INTELLECTUAL DISABILITY, OBESITY, AND DYSMORPHIC FEATURES 2
            MEHMO syndrome 1
            MOMES Syndrome 0
            MORM Syndrome 1
            Macrosomia Obesity Macrocephaly Ocular Abnormalities 0
            Metabolically Benign Obesity 0
            Midface Hypoplasia, Obesity, Developmental Delay, and Neonatal Hypotonia 0
            Obesity Hypoventilation Syndrome 0
            Obesity and Hypopigmentation 3
            Obesity, Hyperphagia, and Developmental Delay 1
            Pediatric Obesity 5
            Prader-Willi syndrome + 18
            Prolactin Deficiency with Obesity and Enlarged Testes 0
            Proopiomelanocortin Deficiency 1
            Retinal Dystrophy and Obesity 2
            SPASTIC PARAPLEGIA, INTELLECTUAL DISABILITY, NYSTAGMUS, AND OBESITY 1
            Short Stature-Obesity Syndrome 0
            Vasquez Hurst Sotos Syndrome 0
            Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome 0
            Wilson-Turner syndrome 3
            Young Hughes Syndrome 0
            morbid obesity + 28
            proprotein convertase 1/3 deficiency 2
Path 2
Term Annotations click to browse term
  disease 15394
    Nutritional and Metabolic Diseases 7361
      disease of metabolism 7361
        acquired metabolic disease 2257
          nutrition disease 810
            overnutrition 601
              obesity 601
                Abdominal Obesity + 23
                Ayazi Syndrome 0
                Biemond Syndrome II 0
                Borjeson-Forssman-Lehmann syndrome 1
                CHOPS Syndrome 1
                Camera Marugo Cohen Syndrome 0
                Clark-Baraitser syndrome 1
                Cohen syndrome 36
                Coloboma-Obesity-Hypogenitalism-Mental Retardation Syndrome 0
                DEVELOPMENTAL DELAY, INTELLECTUAL DISABILITY, OBESITY, AND DYSMORPHIC FEATURES 2
                MEHMO syndrome 1
                MOMES Syndrome 0
                MORM Syndrome 1
                Macrosomia Obesity Macrocephaly Ocular Abnormalities 0
                Metabolically Benign Obesity 0
                Midface Hypoplasia, Obesity, Developmental Delay, and Neonatal Hypotonia 0
                Obesity Hypoventilation Syndrome 0
                Obesity and Hypopigmentation 3
                Obesity, Hyperphagia, and Developmental Delay 1
                Pediatric Obesity 5
                Prader-Willi syndrome + 18
                Prolactin Deficiency with Obesity and Enlarged Testes 0
                Proopiomelanocortin Deficiency 1
                Retinal Dystrophy and Obesity 2
                SPASTIC PARAPLEGIA, INTELLECTUAL DISABILITY, NYSTAGMUS, AND OBESITY 1
                Short Stature-Obesity Syndrome 0
                Vasquez Hurst Sotos Syndrome 0
                Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation, and Obesity Syndrome 0
                Wilson-Turner syndrome 3
                Young Hughes Syndrome 0
                morbid obesity + 28
                proprotein convertase 1/3 deficiency 2
paths to the root