NPY (neuropeptide Y) - Rat Genome Database

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Gene: NPY (neuropeptide Y) Sus scrofa
Analyze
Symbol: NPY
Name: neuropeptide Y
RGD ID: 14015891
Description: ENCODES a protein that exhibits neuropeptide Y receptor binding (ortholog); INVOLVED IN negative regulation of somatostatin secretion; positive regulation of somatostatin secretion; adult feeding behavior (ortholog); PARTICIPATES IN neuropeptide Y metabolic pathway; ASSOCIATED WITH AIDS Dementia Complex (ortholog); alcohol dependence (ortholog); alcohol use disorder (ortholog); FOUND IN extracellular space (ortholog); GABA-ergic synapse (ortholog); neuronal dense core vesicle (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: pro-neuropeptide Y
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1847,985,725 - 47,992,667 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11847,985,796 - 47,993,726 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21852,929,745 - 52,937,666 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:1576993   PMID:2372534   PMID:6957876   PMID:8837218   PMID:15178255   PMID:15623437   PMID:18319138   PMID:19560702   PMID:22301074   PMID:30032202   PMID:30094604   PMID:32493842  


Genomics

Comparative Map Data
NPY
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1847,985,725 - 47,992,667 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11847,985,796 - 47,993,726 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21852,929,745 - 52,937,666 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NPY
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38724,284,190 - 24,291,862 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl724,284,188 - 24,291,862 (+)EnsemblGRCh38hg38GRCh38
GRCh37724,323,809 - 24,331,481 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36724,290,334 - 24,298,002 (+)NCBINCBI36Build 36hg18NCBI36
Build 34724,097,048 - 24,104,717NCBI
Celera724,312,617 - 24,320,302 (+)NCBICelera
Cytogenetic Map7p15.3NCBI
HuRef724,208,802 - 24,216,490 (+)NCBIHuRef
CHM1_1724,325,406 - 24,333,092 (+)NCBICHM1_1
T2T-CHM13v2.0724,422,184 - 24,429,876 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2724,375,683 - 24,383,371 (+)NCBI
Npy
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39649,799,690 - 49,806,487 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl649,799,690 - 49,806,487 (+)EnsemblGRCm39 Ensembl
GRCm38649,822,710 - 49,829,507 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl649,822,710 - 49,829,507 (+)EnsemblGRCm38mm10GRCm38
MGSCv37649,772,728 - 49,779,506 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36649,752,315 - 49,759,093 (+)NCBIMGSCv36mm8
Celera650,334,213 - 50,340,981 (+)NCBICelera
Cytogenetic Map6B2.3NCBI
cM Map624.04NCBI
Npy
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8480,212,111 - 80,219,310 (+)NCBIGRCr8
mRatBN7.2478,881,294 - 78,888,495 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl478,881,264 - 78,888,495 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx484,098,422 - 84,105,619 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0479,873,911 - 79,881,112 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0478,314,242 - 78,321,437 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0479,557,856 - 79,565,059 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl479,573,998 - 79,581,208 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl479,557,854 - 79,565,097 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04144,233,753 - 144,240,956 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4478,038,013 - 78,045,187 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1478,314,142 - 78,321,317 (+)NCBI
Celera473,795,148 - 73,802,371 (+)NCBICelera
RH 3.4 Map4508.6RGD
RH 3.4 Map4507.8RGD
Cytogenetic Map4q24NCBI
Npy
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541026,348,504 - 26,355,297 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541026,348,388 - 26,355,232 (+)NCBIChiLan1.0ChiLan1.0
NPY
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2629,145,106 - 29,152,854 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1777,469,833 - 77,477,581 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0724,963,056 - 24,970,803 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1724,566,963 - 24,574,657 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl724,568,041 - 24,574,657 (+)Ensemblpanpan1.1panPan2
NPY
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11437,824,579 - 37,831,289 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1437,823,861 - 37,831,443 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1437,373,133 - 37,380,851 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01437,758,052 - 37,765,788 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1437,758,938 - 37,765,943 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11437,872,113 - 37,879,841 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01437,564,477 - 37,572,202 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01437,908,665 - 37,916,390 (+)NCBIUU_Cfam_GSD_1.0
Npy
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511882,077,623 - 82,085,085 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364781,290,505 - 1,296,874 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364781,289,437 - 1,296,819 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPY
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12134,068,533 - 34,076,205 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2134,068,530 - 34,075,127 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604270,564,869 - 70,572,551 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Npy
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247396,277,612 - 6,285,397 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247396,277,704 - 6,285,454 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NPY
381 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system hemolymphoid system nervous system
High
Medium 9
Low 3 1 5
Below cutoff 4 2 2

Sequence


RefSeq Acc Id: ENSSSCT00000018199   ⟹   ENSSSCP00000017708
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1847,985,725 - 47,992,667 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000044922   ⟹   ENSSSCP00000041417
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1847,987,822 - 47,993,289 (-)Ensembl
RefSeq Acc Id: NM_001256367   ⟹   NP_001243296
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11847,985,796 - 47,993,726 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001243296   ⟸   NM_001256367
- Peptide Label: precursor
- UniProtKB: F1ST92 (UniProtKB/TrEMBL),   A0A4X1U5L6 (UniProtKB/TrEMBL),   H2DHJ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000041417   ⟸   ENSSSCT00000044922
RefSeq Acc Id: ENSSSCP00000017708   ⟸   ENSSSCT00000018199


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016718 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015036688 UniProtKB/TrEMBL
  ENSSSCG00025011566 UniProtKB/TrEMBL
  ENSSSCG00030005668 UniProtKB/TrEMBL
  ENSSSCG00035051178 UniProtKB/TrEMBL
  ENSSSCG00040010479 UniProtKB/TrEMBL
  ENSSSCG00045029997 UniProtKB/TrEMBL
  ENSSSCG00050050343 UniProtKB/TrEMBL
  ENSSSCG00055001695 UniProtKB/TrEMBL
  ENSSSCG00060000407 UniProtKB/TrEMBL
  ENSSSCG00065076245 UniProtKB/TrEMBL
  ENSSSCG00070014187 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000018199 ENTREZGENE
  ENSSSCT00000018199.5 UniProtKB/TrEMBL
  ENSSSCT00015048742.1 UniProtKB/TrEMBL
  ENSSSCT00025015265.1 UniProtKB/TrEMBL
  ENSSSCT00030007714.1 UniProtKB/TrEMBL
  ENSSSCT00035068176.1 UniProtKB/TrEMBL
  ENSSSCT00040013630.1 UniProtKB/TrEMBL
  ENSSSCT00045051178.1 UniProtKB/TrEMBL
  ENSSSCT00045051232.1 UniProtKB/TrEMBL
  ENSSSCT00050068500.1 UniProtKB/TrEMBL
  ENSSSCT00055003078.1 UniProtKB/TrEMBL
  ENSSSCT00060000455.1 UniProtKB/TrEMBL
  ENSSSCT00060000461.1 UniProtKB/TrEMBL
  ENSSSCT00065105273.1 UniProtKB/TrEMBL
  ENSSSCT00070027802.1 UniProtKB/TrEMBL
  ENSSSCT00070027807.1 UniProtKB/TrEMBL
  ENSSSCT00070027819.1 UniProtKB/TrEMBL
  ENSSSCT00070027825.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.250.900 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Pancreatic_hormone-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pancreatic_hormone-like_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397304 UniProtKB/TrEMBL
NCBI Gene NPY ENTREZGENE
PANTHER PRO-NEUROPEPTIDE Y UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10533 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hormone_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS PANCHORMONE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PANCREATIC_HORMONE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PANCREATIC_HORMONE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PAH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A4X1U0F1_PIG UniProtKB/TrEMBL
  A0A4X1U5L6 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U5M6_PIG UniProtKB/TrEMBL
  F1ST92 ENTREZGENE
  H2DHJ9 ENTREZGENE, UniProtKB/TrEMBL
  NPY_PIG UniProtKB/Swiss-Prot, ENTREZGENE
  Q206J5_PIG UniProtKB/TrEMBL
  Q206J6_PIG UniProtKB/TrEMBL
UniProt Secondary F1ST92 UniProtKB/TrEMBL
  Q9N0M5 UniProtKB/Swiss-Prot
VGNC ID VGNC:98159 ENTREZGENE