RBP4 (retinol binding protein 4) - Rat Genome Database

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Gene: RBP4 (retinol binding protein 4) Sus scrofa
Analyze
Symbol: RBP4
Name: retinol binding protein 4
RGD ID: 13906471
Description: ENCODES a protein that exhibits retinol binding; protein-containing complex binding (ortholog); INVOLVED IN cardiac muscle tissue development (ortholog); detection of light stimulus involved in visual perception (ortholog); embryonic organ morphogenesis (ortholog); PARTICIPATES IN retinoic acid metabolic pathway; ASSOCIATED WITH Alcoholic Liver Diseases (ortholog); Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); FOUND IN extracellular space; protein-containing complex (ortholog); INTERACTS WITH ammonia; progesterone; resveratrol
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Plasma retinol-binding protein; PRBP; RBP; retinol-binding protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14105,037,464 - 105,044,765 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114105,037,360 - 105,044,552 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214114,769,053 - 114,775,781 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
ammonia  (EXP)
progesterone  (EXP)
resveratrol  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:1723146   PMID:2340335   PMID:9757135   PMID:14681463   PMID:15679890   PMID:17145712   PMID:17177694   PMID:18537906   PMID:19138903   PMID:20466637   PMID:20576168   PMID:21113678  
PMID:23859018   PMID:27824510   PMID:31025395  


Genomics

Comparative Map Data
RBP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14105,037,464 - 105,044,765 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114105,037,360 - 105,044,552 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214114,769,053 - 114,775,781 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RBP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381093,591,694 - 93,601,744 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1093,591,687 - 93,601,744 (-)EnsemblGRCh38hg38GRCh38
GRCh371095,351,451 - 95,361,501 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361095,341,583 - 95,350,983 (-)NCBINCBI36Build 36hg18NCBI36
Build 341095,341,583 - 95,350,983NCBI
Celera1089,092,718 - 89,102,118 (-)NCBICelera
Cytogenetic Map10q23.33NCBI
HuRef1088,979,353 - 88,988,753 (-)NCBIHuRef
CHM1_11095,634,147 - 95,643,547 (-)NCBICHM1_1
T2T-CHM13v2.01094,471,646 - 94,481,695 (-)NCBIT2T-CHM13v2.0
Rbp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391938,105,068 - 38,113,769 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1938,105,077 - 38,113,729 (-)EnsemblGRCm39 Ensembl
GRCm381938,116,620 - 38,125,321 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1938,116,629 - 38,125,281 (-)EnsemblGRCm38mm10GRCm38
MGSCv371938,191,110 - 38,199,811 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361938,181,773 - 38,190,392 (-)NCBIMGSCv36mm8
Celera1938,908,311 - 38,919,212 (-)NCBICelera
Cytogenetic Map19C2NCBI
cM Map1932.75NCBI
Rbp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21235,893,917 - 235,901,315 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1235,893,917 - 235,901,399 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1244,315,318 - 244,322,517 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01251,211,097 - 251,218,299 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01244,049,331 - 244,056,533 (-)NCBIRnor_WKY
Rnor_6.01256,806,476 - 256,813,678 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1256,806,472 - 256,813,711 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01264,286,998 - 264,294,396 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,443,795 - 242,450,997 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11242,637,193 - 242,644,147 (-)NCBI
Celera1232,987,269 - 232,994,470 (-)NCBICelera
RH 3.4 Map11581.5RGD
Cytogenetic Map1q53NCBI
Rbp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955507108,669 - 120,584 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955507112,342 - 120,050 (-)NCBIChiLan1.0ChiLan1.0
RBP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11093,848,166 - 93,857,679 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1093,848,166 - 93,857,887 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01090,337,879 - 90,347,530 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
RBP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1287,822,936 - 7,830,735 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl287,822,944 - 7,830,750 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha287,999,367 - 8,007,133 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0288,083,216 - 8,090,965 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl288,083,226 - 8,090,980 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1287,802,939 - 7,810,708 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0287,832,158 - 7,839,906 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0288,002,083 - 8,009,832 (-)NCBIUU_Cfam_GSD_1.0
Rbp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721339,768,612 - 39,777,592 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366011,402,691 - 1,410,208 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049366011,401,215 - 1,410,195 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1986,831,042 - 86,840,668 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl986,830,957 - 86,840,250 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604847,606,135 - 47,615,805 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rbp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247374,791,628 - 4,800,989 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247374,795,054 - 4,800,830 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system
High
Medium 1 5
Low 2 2 2 2 1 15 1
Below cutoff 4 1 1 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_214057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021072103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002338287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK233463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK346172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK346239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY609896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT954211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ344026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU235741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU263980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ869919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU932906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC865727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC865728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC865729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC865730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M68860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000011467   ⟹   ENSSSCP00000011168
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl14105,037,464 - 105,044,765 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000061402   ⟹   ENSSSCP00000038691
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl14105,036,770 - 105,044,765 (-)Ensembl
RefSeq Acc Id: NM_214057   ⟹   NP_999222
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.114105,037,463 - 105,044,191 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021072103   ⟹   XP_020927762
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.114105,037,360 - 105,044,552 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002338287
RefSeq Status:
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.114105,037,360 - 105,044,340 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_020927762   ⟸   XM_021072103
- Peptide Label: isoform X1
- UniProtKB: A0A4X1UUT1 (UniProtKB/TrEMBL),   F1SC80 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_999222   ⟸   NM_214057
- Peptide Label: precursor
- UniProtKB: P27485 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000011168   ⟸   ENSSSCT00000011467
RefSeq Acc Id: ENSSSCP00000038691   ⟸   ENSSSCT00000061402
Protein Domains
Lipocln_cytosolic_FA-bd_dom


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010479 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015042675 UniProtKB/TrEMBL
  ENSSSCG00025008896 UniProtKB/TrEMBL
  ENSSSCG00030047319 UniProtKB/TrEMBL
  ENSSSCG00035028197 UniProtKB/TrEMBL
  ENSSSCG00040016649 UniProtKB/TrEMBL
  ENSSSCG00045002778 UniProtKB/TrEMBL
  ENSSSCG00050075400 UniProtKB/TrEMBL
  ENSSSCG00055029077 UniProtKB/TrEMBL
  ENSSSCG00060002466 UniProtKB/TrEMBL
  ENSSSCG00065002714 UniProtKB/TrEMBL
  ENSSSCG00070019610 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000011168 ENTREZGENE
  ENSSSCP00000011168.2 UniProtKB/TrEMBL
  ENSSSCP00000038691.2 UniProtKB/TrEMBL
  ENSSSCP00015022813.1 UniProtKB/TrEMBL
  ENSSSCP00025004707.1 UniProtKB/TrEMBL
  ENSSSCP00025004718.1 UniProtKB/TrEMBL
  ENSSSCP00030030243.1 UniProtKB/TrEMBL
  ENSSSCP00030030260.1 UniProtKB/TrEMBL
  ENSSSCP00035014868.1 UniProtKB/TrEMBL
  ENSSSCP00040009378.1 UniProtKB/TrEMBL
  ENSSSCP00040009398.1 UniProtKB/TrEMBL
  ENSSSCP00045002776.1 UniProtKB/TrEMBL
  ENSSSCP00045002790.1 UniProtKB/TrEMBL
  ENSSSCP00050045190.1 UniProtKB/TrEMBL
  ENSSSCP00050045193.1 UniProtKB/TrEMBL
  ENSSSCP00055046189.1 UniProtKB/TrEMBL
  ENSSSCP00055046207.1 UniProtKB/TrEMBL
  ENSSSCP00060000964.1 UniProtKB/TrEMBL
  ENSSSCP00065001274.1 UniProtKB/TrEMBL
  ENSSSCP00070032436.1 UniProtKB/TrEMBL
  ENSSSCP00070032441.1 UniProtKB/TrEMBL
  ENSSSCP00070032451.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000011467 ENTREZGENE
  ENSSSCT00000011467.4 UniProtKB/TrEMBL
  ENSSSCT00000061402.2 UniProtKB/TrEMBL
  ENSSSCT00015056942.1 UniProtKB/TrEMBL
  ENSSSCT00025011806.1 UniProtKB/TrEMBL
  ENSSSCT00025011834.1 UniProtKB/TrEMBL
  ENSSSCT00030066048.1 UniProtKB/TrEMBL
  ENSSSCT00030066081.1 UniProtKB/TrEMBL
  ENSSSCT00035037297.1 UniProtKB/TrEMBL
  ENSSSCT00040022400.1 UniProtKB/TrEMBL
  ENSSSCT00040022433.1 UniProtKB/TrEMBL
  ENSSSCT00045004347.1 UniProtKB/TrEMBL
  ENSSSCT00045004365.1 UniProtKB/TrEMBL
  ENSSSCT00050103373.1 UniProtKB/TrEMBL
  ENSSSCT00050103376.1 UniProtKB/TrEMBL
  ENSSSCT00055057723.1 UniProtKB/TrEMBL
  ENSSSCT00055057745.1 UniProtKB/TrEMBL
  ENSSSCT00060003018.1 UniProtKB/TrEMBL
  ENSSSCT00065003490.1 UniProtKB/TrEMBL
  ENSSSCT00070038759.1 UniProtKB/TrEMBL
  ENSSSCT00070038764.1 UniProtKB/TrEMBL
  ENSSSCT00070038775.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.128.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Calycin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipocalin_ApoD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipocalin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipocln_cytosolic_FA-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Retinol-bd/Purpurin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397124 UniProtKB/Swiss-Prot
NCBI Gene RBP4 ENTREZGENE
PANTHER PTHR11873 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Lipocalin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF Lipocalin_ApoD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBP_purpurin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS RETINOLBNDNG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE LIPOCALIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50814 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A287A3Z4_PIG UniProtKB/TrEMBL
  A0A4X1UUR6_PIG UniProtKB/TrEMBL
  A0A4X1UUS0_PIG UniProtKB/TrEMBL
  A0A4X1UUT1 ENTREZGENE, UniProtKB/TrEMBL
  A8WE73_PIG UniProtKB/TrEMBL
  D5LIR8_PIG UniProtKB/TrEMBL
  F1SC80 ENTREZGENE, UniProtKB/TrEMBL
  P27485 ENTREZGENE, UniProtKB/Swiss-Prot
  S5PVD2_PIG UniProtKB/TrEMBL
  S5QC36_PIG UniProtKB/TrEMBL
VGNC ID VGNC:92164 ENTREZGENE