FGFR1 (fibroblast growth factor receptor 1)

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Gene: FGFR1 (fibroblast growth factor receptor 1) Sus scrofa

Analyze

Symbol:

FGFR1

Name:

fibroblast growth factor receptor 1

RGD ID:

13891245

Description:

ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); protein-containing complex binding (ortholog); SH2 domain binding (ortholog); INVOLVED IN angiogenesis (ortholog); auditory receptor cell development (ortholog); blood vessel morphogenesis (ortholog); PARTICIPATES IN cerium oxide nanoparticle response pathway; fibroblast growth factor signaling pathway; glypican signaling pathway; ASSOCIATED WITH acoustic neuroma (ortholog); acrocephalosyndactylia (ortholog); Acute Lymphoblastic Leukemia, with Lymphomatous Features (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH progesterone

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

FGF receptor; FGFR1IIIC

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Dog

Squirrel

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	48,053,340 - 48,106,746 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	48,053,895 - 48,106,634 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	55,216,111 - 55,269,152 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acoustic neuroma (ISO)

acrocephalosyndactylia (ISO)

Acute Lymphoblastic Leukemia, with Lymphomatous Features (ISO)

acute myeloid leukemia (ISO)

Acute Otitis Media (ISO)

Alzheimer's disease (ISO)

amenorrhea (ISO)

atypical chronic myeloid leukemia (ISO)

Breast Neoplasms (ISO)

Burns (ISO)

cerebellar hypoplasia (ISO)

cleft lip (ISO)

cleft palate (ISO)

Congenital Foot Deformities (ISO)

Craniofacial Abnormalities (ISO)

craniosynostosis (ISO)

Craniosynostosis Syndrome, Autosomal Recessive (ISO)

Delayed Puberty (ISO)

demyelinating disease (ISO)

disease of cellular proliferation (ISO)

Encephalocraniocutaneous Lipomatosis (ISO)

Experimental Arthritis (ISO)

Experimental Leukemia (ISO)

Experimental Liver Cirrhosis (ISO)

fatty liver disease (ISO)

Femoral Fractures (ISO)

fibrolamellar carcinoma (ISO)

gastric adenocarcinoma (ISO)

genetic disease (ISO)

glioblastoma (ISO)

Head Injuries, Penetrating (ISO)

heart valve disease (ISO)

hepatocellular carcinoma (ISO)

high grade glioma (ISO)

holoprosencephaly (ISO)

Holoprosencephaly, Ectrodactyly, and Bilateral Cleft Lip/Palate (ISO)

Hypoglossal Nerve Injuries (ISO)

hypogonadotropic hypogonadism (ISO)

hypogonadotropic hypogonadism 2 with or without anosmia (ISO)

hypogonadotropic hypogonadism 7 with or without anosmia (ISO)

Hypogonadotropic Hypogonadism and Anosmia, Autosomal Dominant (ISO)

infertility (ISO)

Jackson-Weiss syndrome (ISO)

Kallmann syndrome (ISO)

Klinefelter syndrome (ISO)

Limb Ischemia (ISO)

Liver Metastasis (ISO)

Lung Neoplasms (ISO)

lung non-small cell carcinoma (ISO)

lung small cell carcinoma (ISO)

malignant astrocytoma (ISO)

medulloblastoma (ISO)

mental depression (ISO)

mesangial proliferative glomerulonephritis (ISO)

mouth disease (ISO)

myeloid leukemia (ISO)

myeloid neoplasm (ISO)

myocardial infarction (ISO)

Neointima (ISO)

Neoplasm Metastasis (ISO)

neuroblastoma (ISO)

non-alcoholic fatty liver disease (ISO)

Nonsyndromic Trigonocephaly (ISO)

obesity (ISO)

osteoarthritis (ISO)

Osteoarthritis, Experimental (ISO)

osteoglophonic dysplasia (ISO)

Pfeiffer syndrome (ISO)

pilomyxoid astrocytoma (ISO)

prostate adenocarcinoma (ISO)

prostate cancer (ISO)

prostate carcinoma in situ (ISO)

pulmonary hypertension (ISO)

renal cell carcinoma (ISO)

retinal detachment (ISO)

schizophrenia (ISO)

sciatic neuropathy (ISO)

squamous cell carcinoma (ISO)

Stargardt Disease 3 (ISO)

T-Cell Lymphoma (ISO)

transient cerebral ischemia (ISO)

transitional cell carcinoma (ISO)

Trigonocephaly 1 (ISO)

Tympanic Membrane Perforation (ISO)

type 2 diabetes mellitus (ISO)

umbilical hernia (ISO)

vascular dementia (ISO)

visual epilepsy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

progesterone (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (ISO)

animal organ development (IEA)

auditory receptor cell development (ISO)

blood vessel morphogenesis (ISO)

brain development (ISO)

branching involved in salivary gland morphogenesis (ISO)

calcium ion homeostasis (ISO)

cardiac muscle cell proliferation (ISO)

cell maturation (ISO)

cell population proliferation (ISO)

cellular response to histamine (ISO)

cellular response to lipopolysaccharide (ISO)

cellular response to nerve growth factor stimulus (ISO)

cementum mineralization (ISO)

central nervous system neuron development (ISO)

chondrocyte differentiation (ISO)

diphosphate metabolic process (ISO)

ear development (ISO)

embryonic limb morphogenesis (ISO)

epithelial to mesenchymal transition (IEA)

female pregnancy (ISO)

fibroblast growth factor receptor signaling pathway (IEA,ISO)

fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development (ISO)

gene expression (ISO)

generation of neurons (ISO)

in utero embryonic development (ISO)

inner ear morphogenesis (ISO)

lung development (ISO)

lung-associated mesenchyme development (ISO)

mesenchymal cell differentiation (ISO)

mesenchymal cell proliferation (ISO)

midbrain development (ISO)

middle ear morphogenesis (ISO)

motogenic signaling involved in postnatal olfactory bulb interneuron migration (ISO)

negative regulation of fibroblast growth factor production (ISO)

negative regulation of gene expression (ISO)

negative regulation of osteoblast differentiation (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

neuron projection development (ISO)

orbitofrontal cortex development (ISO)

organ induction (ISO)

outer ear morphogenesis (ISO)

paraxial mesoderm development (ISO)

peptidyl-tyrosine phosphorylation (IEA)

phosphorylation (IEA)

positive regulation of blood vessel endothelial cell migration (IEA)

positive regulation of cardiac muscle cell proliferation (ISO)

positive regulation of cell cycle (ISO)

positive regulation of cell differentiation (IBA)

positive regulation of cell population proliferation (IEA,ISO)

positive regulation of endothelial cell chemotaxis to fibroblast growth factor (IEA)

positive regulation of fibroblast migration (ISO)

positive regulation of hepatic stellate cell activation (ISO)

positive regulation of inflammatory response (ISO)

positive regulation of kinase activity (IBA)

positive regulation of MAP kinase activity (IEA)

positive regulation of MAPK cascade (IEA)

positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway (ISO)

positive regulation of mesenchymal cell proliferation (ISO)

positive regulation of mitotic cell cycle DNA replication (ISO)

positive regulation of neuron differentiation (IEA)

positive regulation of neuron projection development (ISO)

positive regulation of parathyroid hormone secretion (ISO)

positive regulation of phospholipase C activity (IEA)

positive regulation of protein kinase B signaling (IEA)

positive regulation of stem cell proliferation (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

positive regulation of vascular endothelial cell proliferation (IEA)

protein autophosphorylation (IEA)

protein phosphorylation (IEA)

regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling (ISO)

regulation of cell population proliferation (ISO)

regulation of epithelial cell proliferation (ISO)

regulation of extrinsic apoptotic signaling pathway in absence of ligand (ISO)

regulation of gene expression (ISO)

regulation of lateral mesodermal cell fate specification (ISO)

regulation of phosphate transport (ISO)

regulation of phosphorus metabolic process (ISO)

regulation of sensory perception of pain (ISO)

regulation of stem cell proliferation (ISO)

response to ischemia (ISO)

response to nutrient levels (ISO)

response to sodium phosphate (ISO)

salivary gland morphogenesis (ISO)

sensory perception of sound (ISO)

stem cell differentiation (ISO)

stem cell population maintenance (ISO)

stem cell proliferation (ISO)

transmembrane receptor protein tyrosine kinase signaling pathway (IBA)

ureteric bud development (ISO)

ventricular zone neuroblast division (ISO)

vitamin D3 metabolic process (ISO)

wound healing (ISO)

Cellular Component

cytoplasm (ISO)

cytoplasmic vesicle (IEA)

cytosol (IEA)

integral component of membrane (IEA)

integral component of plasma membrane (IBA)

membrane (IEA)

nucleus (IEA,ISO)

perinuclear region of cytoplasm (ISO)

plasma membrane (IEA,ISO)

receptor complex (IBA,IEA)

Molecular Function

ATP binding (IEA)

cell adhesion molecule binding (ISO)

fibroblast growth factor binding (IBA,IEA)

fibroblast growth factor receptor activity (IBA,IEA)

heparin binding (IEA)

identical protein binding (IEA)

kinase activity (IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein homodimerization activity (IEA)

protein kinase activity (IEA)

protein serine/threonine/tyrosine kinase activity (IEA)

protein tyrosine kinase activity (IEA)

protein-containing complex binding (ISO)

receptor-receptor interaction (IEA)

SH2 domain binding (ISO)

signaling receptor binding (ISO)

transferase activity (IEA)

transmembrane receptor protein tyrosine kinase activity (IBA,IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

cerium oxide nanoparticle response pathway (ISO)

fibroblast growth factor signaling pathway (ISO)

glypican signaling pathway (ISO)

N-cadherin signaling pathway (ISO)

syndecan signaling pathway (ISO)

References

Additional References at PubMed

PMID:14681463	PMID:15120423	PMID:17145712	PMID:21478100	PMID:31671754

Genomics

Comparative Map Data

FGFR1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	48,053,340 - 48,106,746 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	48,053,895 - 48,106,634 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	55,216,111 - 55,269,152 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FGFR1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	38,411,143 - 38,468,635 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	8	38,400,215 - 38,468,834 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	38,268,661 - 38,326,153 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	38,387,813 - 38,445,509 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	8	38,389,448 - 38,445,293	NCBI
Celera	8	37,221,633 - 37,279,334 (-)	NCBI
Cytogenetic Map	8	p11.23	NCBI
HuRef	8	36,802,638 - 36,860,684 (-)	NCBI		HuRef
CHM1_1	8	38,470,562 - 38,528,261 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	38,688,107 - 38,745,588 (-)	NCBI

Fgfr1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	26,008,775 - 26,065,734 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	8	26,003,670 - 26,065,734 (+)	Ensembl
GRCm38	8	25,518,759 - 25,575,718 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	25,513,654 - 25,575,718 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	26,629,244 - 26,686,186 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	8	26,997,826 - 27,039,466 (+)	NCBI			mm8
Celera	8	26,986,822 - 27,044,074 (+)	NCBI		Celera
Cytogenetic Map	8	A2	NCBI
cM Map	8	14.12	NCBI

Fgfr1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	16	66,492,445 - 66,546,731 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	16	66,494,042 - 66,547,350 (-)	Ensembl
Rnor_6.0	16	71,265,390 - 71,319,046 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	71,266,248 - 71,319,449 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	70,924,716 - 70,977,998 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	70,869,974 - 70,910,045 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	16	70,870,238 - 70,910,310 (-)	NCBI
Celera	16	64,402,647 - 64,442,189 (-)	NCBI		Celera
Cytogenetic Map	16	q12.4	NCBI

Fgfr1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955463	14,013,247 - 14,064,111 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955463	14,013,247 - 14,064,354 (-)	NCBI	ChiLan1.0	ChiLan1.0

FGFR1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	8	34,890,147 - 34,948,904 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	34,890,147 - 34,948,904 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	8	37,713,133 - 37,773,098 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

FGFR1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	27,029,902 - 27,080,514 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	27,031,588 - 27,078,261 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	27,547,259 - 27,597,845 (+)	NCBI
ROS_Cfam_1.0	16	28,928,146 - 28,978,790 (+)	NCBI
ROS_Cfam_1.0 Ensembl	16	28,927,382 - 28,977,436 (+)	Ensembl
UMICH_Zoey_3.1	16	27,151,667 - 27,202,222 (+)	NCBI
UNSW_CanFamBas_1.0	16	27,728,739 - 27,779,306 (+)	NCBI
UU_Cfam_GSD_1.0	16	27,767,626 - 27,818,261 (+)	NCBI

Fgfr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	49,645,976 - 49,698,868 (+)	NCBI
SpeTri2.0	NW_004936710	1,760,365 - 1,815,269 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FGFR1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	36,426,116 - 36,485,683 (-)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	8	36,427,110 - 36,485,508 (-)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666052	5,502,205 - 5,561,763 (+)	NCBI	Vero_WHO_p1.0

Fgfr1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624780	5,161,073 - 5,213,870 (+)	Ensembl	HetGla_female_1.0		hetGla2
HetGla 1.0	NW_004624780	5,161,245 - 5,212,641 (+)	NCBI	HetGla_female_1.0		hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium	2	1	3			9
Low	8	3		5	2	14	2	3	1
Below cutoff									2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005671767	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000099	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ577088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK236501	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK347378	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU571183	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01091861	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSSSCT00000017223 ⟹ ENSSSCP00000016761

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	15	48,053,367 - 48,106,746 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000033078 ⟹ ENSSSCP00000030160

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	15	48,054,285 - 48,106,746 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000069535 ⟹ ENSSSCP00000066797

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	15	48,053,367 - 48,100,802 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000083142 ⟹ ENSSSCP00000064455

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	15	48,053,340 - 48,106,746 (+)	Ensembl

RefSeq Acc Id:

XM_005671767 ⟹ XP_005671824

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	15	48,053,895 - 48,106,634 (+)	NCBI

Sequence:

show sequence

GCGGCCCCGCCAGGACCGGAGCGGAGCCCGGGGGCGGCGGGCCGGAGCCGAGGACGCGGGCGCC
CGCCCGCCCGCACAAGCCACGGCGGACTCTCCAGAGGCGGAATCGCCGAGCCCAGTGAGAGTCA
GCTCACCAACGAGGATCAAGCCCACAGCAGCGTCTCCATGGAGGTGTGGAGCCTGGTCACCAAC
CTCTAACCGCAGAACTGGGATGTGCAGCTGGAAGTGCCTCCTCTTCTGGGCTGTGCTGGTCACA
GCCACGCTCTGCACGGCCAGGCCGGCTCCGACCTCGCCGGAACAAGCTCAGCCCTGGGGAGCCC
CCGTGGAAGTGGAGTCCTTCCTGGTCCACCCCGGTGACCTGCTGCAGCTCCGCTGTCGGCTGCG
GGACGATGTTCAGAGCATCAACTGGCTGCGGGACGGGGTGCAGCTGGTGGAAAGCAACCGCACC
CGCATCACAGGGGAGGAGGTGGAGGTGCGGGACTCCGTGCCCTCCGACTCCGGCCTCTACGCCT
GTGTGACCAGCAGCCCCTCGGGCAGCGACACCACCTACTTCTCCGTCAACGTCTCAGATGCTCT
CCCCTCTTCGGAGGATGACGATGACGATGATGACTCCTCCTCAGAGGAGAAAGAGACAGATAAC
ACCAAACCAAACCGTATGCCCGTGGCTCCGTACTGGACATCCCCAGAGAAGATGGAAAAGAAAT
TGCATGCGGTGCCAGCTGCCAAGACAGTGAAGTTCAAGTGCCCCTCCAGTGGGACTCCTAACCC
CACCTTGCGCTGGCTGAAAAATGGCAAAGAATTCAAGCCTGACCACAGAATCGGAGGCTACAAG
GTCCGTTATGCCACCTGGAGCATCATCATGGACTCCGTGGTGCCCTCCGACAAGGGCAACTACA
CCTGCGTCGTGGAGAACGAGTATGGCAGCATCAACCACACCTACCAGCTTGACGTTGTGGAGCG
GTCCCCTCACCGGCCCATCCTGCAGGCAGGGTTGCCAGCCAACAAGACAGTGGCCCTGGGCAGC
AATGTGGAATTCATGTGCAAGGTGTACAGTGACCCACAGCCCCACATCCAGTGGCTAAAGCACA
TCGAGGTGAATGGGAGTAAGATTGGTCCGGACAACCTACCTTATGTCCAGATCTTGAAGACTGC
CGGCGTTAATACCACCGACAAAGAGATGGAGGTGCTCCACTTAAGGAATGTCTCCTTTGAGGAC
GCGGGGGAGTATACATGCTTGGCGGGTAACTCTATCGGACTCTCCCATCACTCTGCATGGTTGA
CCGTTCTGGAAGCCCTGGAAGAGCGCCCGGCGGTGATGACCTCGCCCTTGTACCTGGAGATCAT
CATCTACTGCACAGGGGCCTTCCTCATCTCCTGCATGGTGGGGTCTGTCATCATCTACAAGATG
AAGAGTGGCACCAAGAAGAGTGACTTCCACAGCCAGATGGCCGTGCACAAGCTGGCCAAGAGCA
TCCCTCTGCGCAGACAGGTGTCGGCTGACTCCAGTGCCTCCATGAACTCCGGGGTCCTACTGGT
TCGGCCGTCGCGTCTCTCCTCCAGTGGGACCCCCATGCTGGCTGGGGTCTCCGAATACGAGCTT
CCTGAAGACCCTCGCTGGGAGCTGCCTCGGGACAGGCTGGTTTTAGGCAAACCCCTGGGAGAGG
GCTGCTTTGGGCAGGTGGTGTTGGCAGAGGCCATTGGGCTGGACAAGGACAAGCCCAACCGTGT
GACCAAAGTGGCTGTGAAGATGCTGAAGTCGGATGCAACAGAGAAAGACCTGTCAGACCTGATC
TCTGAGATGGAGATGATGAAGATGATTGGGAAGCACAAGAACATCATCAACCTGCTGGGGGCCT
GCACGCAGGACGGACCTCTATATGTCATTGTGGAGTATGCCTCCAAGGGCAACCTCCGTGAGTA
CCTGCAGGCCCGGAGGCCACCTGGGCTGGAATACTGCTACAACCCCAGCCACAACCCGGAGGAG
CAGCTCTCCTCCAAGGACCTGGTCTCCTGTGCCTATCAGGTGGCTCGAGGCATGGAGTACCTCG
CTTCCAAGAAGTGCATACACCGAGACCTGGCCGCCAGGAACGTCCTGGTGACGGAGNACAACGT
GATGAAGATCGCAGACTTTGGCCTTGCCCGGGACATCCACCACATTGACTACTACAAAAAGACA
ACCAACGGCCGACTGCCGGTGAAGTGGATGGCACCGGAGNCTTTGTTTGACCGGATCTACACCC
ACCAGAGTGACGTGTGGTCTTTTGGGGTGCTCCTGTGGGAAATCTTCACTCTGGGCGGCTCCCC
ATACCCTGGCGTCCCTGTGGAGGAGCTTTTCAAGCTGTTGAAGGAGGGTCATCGGATGGACAAG
CCCAGTAACTGCACCCATGAACTATACATGATGATGCGAGACTGTTGGCACGCGGTACCCTCCC
AGAGACCTACCTTCAAGCAGCTGGTGGAAGACCTGGACCGCATTGTGGCCTTGACCTCCAACCA
GGAGTATCTGGACCTGTCGATGCCCCTGGACCAGTACTCCCCCAGCTTCCCTGACACCCGCAGC
TCTACCTGCTCCTCTGGGGAAGATTCCGTCTTCTCTCACGAACCCTTGCCCGAGGAGCCCTGCC
TGCCCCGACACCCACCCCAGCTTGCCAACGGCGGACTCAAACGGCGCTGACCGGCACCCTGGCA
CCCCTCCCCAAACTCCATCCTTAGCTGTGACCCCTCCCCGCTCCTGCTGGACTCCGCCCCACCC
CGCCCCTTCCTGCTGGCAGGAGCCAGCTGCCTACCTGGGGCCTTCACCCCCAGTTCCCTTCTCC
ACCTCCCCCTCCTCTCAGCCTGCTGGTGCAACAGAGGAACAGGGAGGCAGGTACTTGCTGACGG
CCACTTTGTTCTCTCCCAGTGTTGGACCAAGACCCCCTCCCCCTCACCGGGCACTGCCTGGAGG
GGTGGGAAGTGGGGGATGAGCAGCACTCGAGCGACTGAGCTTTCCGGTGTTGGTTTTGTCTGCT
CCATGCAGCCTGTCCACCCGGGTTCTGGTGGCAGGTCCTTGGGCTACAGCAGTGGTTGGGGGCG
GGGTCAGTGCTTGGGCCTCTGCGCCAGATGGATGGTGCCAAGGGCTTCTTAATTCCAATACTAA
TGTGCTTTGCTGACCAAATACCTGGTACCAGAGGATGGAGTTGCAGAGGCTGGAAGCAGTGTGG
TGGCCCTGGGGCCCAGCCCCAAACCAGGGGCTTTGTACATAGCTACGAAGAAAACACAAAGTGT
ATAAATCTGAGTATATATTTACAT

hide sequence

Protein Sequences


Protein RefSeqs	XP_005671824	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAE11790	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_005671824 ⟸ XM_005671767

- Sequence:

show sequence

MCSWKCLLFWAVLVTATLCTARPAPTSPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSI
NWLRDGVQLVESNRTRITGEEVEVRDSVPSDSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDD
DDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLK
NGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCVVENEYGSINHTYQLDVVERSPHRPI
LQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTD
KEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGA
FLISCMVGSVIIYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVSADSSASMNSGVLLVRPSRLS
SSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVK
MLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP
PGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEXNVMKIADF
GLARDIHHIDYYKKTTNGRLPVKWMAPEXLFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV
EELFKLLKEGHRMDKPSNCTHELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLS
MPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPPQLANGGLKRR

hide sequence

RefSeq Acc Id:

ENSSSCP00000064455 ⟸ ENSSSCT00000083142

RefSeq Acc Id:

ENSSSCP00000066797 ⟸ ENSSSCT00000069535

RefSeq Acc Id:

ENSSSCP00000016761 ⟸ ENSSSCT00000017223

RefSeq Acc Id:

ENSSSCP00000030160 ⟸ ENSSSCT00000033078

Protein Domains

Ig-like Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000015815	Ensembl, UniProtKB/TrEMBL
	ENSSSCG00005035742	UniProtKB/TrEMBL
	ENSSSCG00015030689	UniProtKB/TrEMBL
	ENSSSCG00025072035	UniProtKB/TrEMBL
	ENSSSCG00030067960	UniProtKB/TrEMBL
	ENSSSCG00035030619	UniProtKB/TrEMBL
	ENSSSCG00040029807	UniProtKB/TrEMBL
	ENSSSCG00045034640	UniProtKB/TrEMBL
	ENSSSCG00050035663	UniProtKB/TrEMBL
	ENSSSCG00055008246	UniProtKB/TrEMBL
	ENSSSCG00060078610	UniProtKB/TrEMBL
	ENSSSCG00065023644	UniProtKB/TrEMBL
	ENSSSCG00070026967	UniProtKB/TrEMBL
Ensembl Protein	ENSSSCP00000016761	UniProtKB/TrEMBL
	ENSSSCP00000030160	UniProtKB/TrEMBL
	ENSSSCP00000064455	UniProtKB/TrEMBL
	ENSSSCP00000066797	UniProtKB/TrEMBL
	ENSSSCP00005035228	UniProtKB/TrEMBL
	ENSSSCP00005035279	UniProtKB/TrEMBL
	ENSSSCP00005035575	UniProtKB/TrEMBL
	ENSSSCP00005035603	UniProtKB/TrEMBL
	ENSSSCP00005035633	UniProtKB/TrEMBL
	ENSSSCP00015016255	UniProtKB/TrEMBL
	ENSSSCP00015016319	UniProtKB/TrEMBL
	ENSSSCP00015016343	UniProtKB/TrEMBL
	ENSSSCP00015016379	UniProtKB/TrEMBL
	ENSSSCP00015016454	UniProtKB/TrEMBL
	ENSSSCP00015016545	UniProtKB/TrEMBL
	ENSSSCP00015016687	UniProtKB/TrEMBL
	ENSSSCP00015016888	UniProtKB/TrEMBL
	ENSSSCP00015016957	UniProtKB/TrEMBL
	ENSSSCP00025043603	UniProtKB/TrEMBL
	ENSSSCP00025043681	UniProtKB/TrEMBL
	ENSSSCP00025043744	UniProtKB/TrEMBL
	ENSSSCP00025043824	UniProtKB/TrEMBL
	ENSSSCP00025043951	UniProtKB/TrEMBL
	ENSSSCP00030043912	UniProtKB/TrEMBL
	ENSSSCP00030043948	UniProtKB/TrEMBL
	ENSSSCP00030043965	UniProtKB/TrEMBL
	ENSSSCP00030044043	UniProtKB/TrEMBL
	ENSSSCP00035016222	UniProtKB/TrEMBL
	ENSSSCP00035016227	UniProtKB/TrEMBL
	ENSSSCP00035016231	UniProtKB/TrEMBL
	ENSSSCP00035016241	UniProtKB/TrEMBL
	ENSSSCP00040016854	UniProtKB/TrEMBL
	ENSSSCP00040016880	UniProtKB/TrEMBL
	ENSSSCP00040016901	UniProtKB/TrEMBL
	ENSSSCP00040016972	UniProtKB/TrEMBL
	ENSSSCP00040017015	UniProtKB/TrEMBL
	ENSSSCP00045041867	UniProtKB/TrEMBL
	ENSSSCP00050019927	UniProtKB/TrEMBL
	ENSSSCP00050019929	UniProtKB/TrEMBL
	ENSSSCP00050019931	UniProtKB/TrEMBL
	ENSSSCP00050019936	UniProtKB/TrEMBL
	ENSSSCP00050019943	UniProtKB/TrEMBL
	ENSSSCP00055012634	UniProtKB/TrEMBL
	ENSSSCP00055012707	UniProtKB/TrEMBL
	ENSSSCP00055012740	UniProtKB/TrEMBL
	ENSSSCP00055012817	UniProtKB/TrEMBL
	ENSSSCP00055012884	UniProtKB/TrEMBL
	ENSSSCP00055012956	UniProtKB/TrEMBL
	ENSSSCP00055013121	UniProtKB/TrEMBL
	ENSSSCP00055013205	UniProtKB/TrEMBL
	ENSSSCP00060048445	UniProtKB/TrEMBL
	ENSSSCP00060048455	UniProtKB/TrEMBL
	ENSSSCP00060048456	UniProtKB/TrEMBL
	ENSSSCP00060048460	UniProtKB/TrEMBL
	ENSSSCP00060048463	UniProtKB/TrEMBL
	ENSSSCP00065012875	UniProtKB/TrEMBL
	ENSSSCP00065012880	UniProtKB/TrEMBL
	ENSSSCP00065012885	UniProtKB/TrEMBL
	ENSSSCP00065012890	UniProtKB/TrEMBL
	ENSSSCP00065012893	UniProtKB/TrEMBL
	ENSSSCP00070045938	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000017223	UniProtKB/TrEMBL
	ENSSSCT00000033078	UniProtKB/TrEMBL
	ENSSSCT00000069535	UniProtKB/TrEMBL
	ENSSSCT00000083142	UniProtKB/TrEMBL
	ENSSSCT00005057214	UniProtKB/TrEMBL
	ENSSSCT00005057290	UniProtKB/TrEMBL
	ENSSSCT00005057727	UniProtKB/TrEMBL
	ENSSSCT00005057773	UniProtKB/TrEMBL
	ENSSSCT00005057811	UniProtKB/TrEMBL
	ENSSSCT00015041122	UniProtKB/TrEMBL
	ENSSSCT00015041315	UniProtKB/TrEMBL
	ENSSSCT00015041363	UniProtKB/TrEMBL
	ENSSSCT00015041456	UniProtKB/TrEMBL
	ENSSSCT00015041636	UniProtKB/TrEMBL
	ENSSSCT00015041906	UniProtKB/TrEMBL
	ENSSSCT00015042222	UniProtKB/TrEMBL
	ENSSSCT00015042735	UniProtKB/TrEMBL
	ENSSSCT00015042884	UniProtKB/TrEMBL
	ENSSSCT00025099119	UniProtKB/TrEMBL
	ENSSSCT00025099293	UniProtKB/TrEMBL
	ENSSSCT00025099387	UniProtKB/TrEMBL
	ENSSSCT00025099512	UniProtKB/TrEMBL
	ENSSSCT00025099743	UniProtKB/TrEMBL
	ENSSSCT00030095295	UniProtKB/TrEMBL
	ENSSSCT00030095374	UniProtKB/TrEMBL
	ENSSSCT00030095408	UniProtKB/TrEMBL
	ENSSSCT00030095605	UniProtKB/TrEMBL
	ENSSSCT00035040555	UniProtKB/TrEMBL
	ENSSSCT00035040568	UniProtKB/TrEMBL
	ENSSSCT00035040575	UniProtKB/TrEMBL
	ENSSSCT00035040588	UniProtKB/TrEMBL
	ENSSSCT00040040171	UniProtKB/TrEMBL
	ENSSSCT00040040227	UniProtKB/TrEMBL
	ENSSSCT00040040269	UniProtKB/TrEMBL
	ENSSSCT00040040493	UniProtKB/TrEMBL
	ENSSSCT00040040603	UniProtKB/TrEMBL
	ENSSSCT00045059681	UniProtKB/TrEMBL
	ENSSSCT00050047947	UniProtKB/TrEMBL
	ENSSSCT00050047950	UniProtKB/TrEMBL
	ENSSSCT00050047953	UniProtKB/TrEMBL
	ENSSSCT00050047963	UniProtKB/TrEMBL
	ENSSSCT00050047974	UniProtKB/TrEMBL
	ENSSSCT00055016062	UniProtKB/TrEMBL
	ENSSSCT00055016150	UniProtKB/TrEMBL
	ENSSSCT00055016194	UniProtKB/TrEMBL
	ENSSSCT00055016276	UniProtKB/TrEMBL
	ENSSSCT00055016354	UniProtKB/TrEMBL
	ENSSSCT00055016445	UniProtKB/TrEMBL
	ENSSSCT00055016635	UniProtKB/TrEMBL
	ENSSSCT00055016737	UniProtKB/TrEMBL
	ENSSSCT00060108644	UniProtKB/TrEMBL
	ENSSSCT00060108655	UniProtKB/TrEMBL
	ENSSSCT00060108656	UniProtKB/TrEMBL
	ENSSSCT00060108660	UniProtKB/TrEMBL
	ENSSSCT00060108663	UniProtKB/TrEMBL
	ENSSSCT00065031468	UniProtKB/TrEMBL
	ENSSSCT00065031475	UniProtKB/TrEMBL
	ENSSSCT00065031485	UniProtKB/TrEMBL
	ENSSSCT00065031507	UniProtKB/TrEMBL
	ENSSSCT00065031519	UniProtKB/TrEMBL
	ENSSSCT00070054181	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	FGF_rcpt_1	UniProtKB/TrEMBL
	FGF_rcpt_fam	UniProtKB/TrEMBL
	Ig-like_dom	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_I-set	UniProtKB/TrEMBL
	Ig_sub	UniProtKB/TrEMBL
	Ig_sub2	UniProtKB/TrEMBL
	Immunoglobulin	UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser-Thr/Tyr_kinase_cat_dom	UniProtKB/TrEMBL
	Tyr_kinase_AS	UniProtKB/TrEMBL
	Tyr_kinase_cat_dom	UniProtKB/TrEMBL
NCBI Gene	FGFR1	ENTREZGENE
Pfam	I-set	UniProtKB/TrEMBL
	PF00047	UniProtKB/TrEMBL
	Pkinase_Tyr	UniProtKB/TrEMBL
PIRSF	FGFR	UniProtKB/TrEMBL
PRINTS	TYRKINASE	UniProtKB/TrEMBL
PROSITE	IG_LIKE	UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_TYR	UniProtKB/TrEMBL
SMART	IGc2	UniProtKB/TrEMBL
	SM00409	UniProtKB/TrEMBL
	TyrKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
	SSF56112	UniProtKB/TrEMBL
UniProt	A0A4X1VXC3_PIG	UniProtKB/TrEMBL
	A0A5G2QI33_PIG	UniProtKB/TrEMBL
	A0A5G2QRT9_PIG	UniProtKB/TrEMBL
	A0A8D0K394_PIG	UniProtKB/TrEMBL
	A0A8D0NBM7_PIG	UniProtKB/TrEMBL
	A0A8D0NG61_PIG	UniProtKB/TrEMBL
	A0A8D0TAQ0_PIG	UniProtKB/TrEMBL
	A0A8D1E4H1_PIG	UniProtKB/TrEMBL
	A0A8D1PY95_PIG	UniProtKB/TrEMBL
	A0A8D1Q0R9_PIG	UniProtKB/TrEMBL
	F1RZJ8_PIG	UniProtKB/TrEMBL
	K7GQJ1_PIG	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)