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Gene: SLC22A3 (solute carrier family 22 member 3) Sus scrofa

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Symbol:

SLC22A3

Name:

solute carrier family 22 member 3

RGD ID:

13853364

Description:

ENCODES a protein that exhibits dopamine:sodium symporter activity (ortholog); organic anion transmembrane transporter activity (ortholog); organic cation transmembrane transporter activity (ortholog); INVOLVED IN dopamine transport (ortholog); establishment of localization in cell (ortholog); histamine transport (ortholog); PARTICIPATES IN lamivudine pharmacokinetics pathway; metformin pharmacokinetics pathway; ASSOCIATED WITH 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (ortholog); Coxsackievirus Infections (ortholog); Kidney Neoplasms (ortholog); FOUND IN apical plasma membrane (inferred); basolateral plasma membrane (inferred); endomembrane system (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

extraneuronal monoamine extraneuronal monoamine; solute carrier family 22 (extraneuronal monoamine transporter), member 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	7,110,074 - 7,207,401 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	7,105,486 - 7,207,395 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	8,787,403 - 8,885,452 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (ISO)

Coxsackievirus Infections (ISO)

Kidney Neoplasms (ISO)

myocarditis (ISO)

obesity (ISO)

Prostatic Neoplasms (ISO)

substance-related disorder (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular detoxification (IEA)

dopamine transport (IEA,ISO)

dopamine uptake (IEA)

epinephrine transport (IEA)

epinephrine uptake (IEA)

establishment of localization in cell (IEA,ISO)

histamine transport (IEA,ISO)

histamine uptake (IEA,ISO)

monoamine transport (IEA,ISO)

monoatomic ion transport (IEA)

monocarboxylic acid transport (IEA,ISO)

neurotransmitter transport (IEA,ISO)

norepinephrine transport (IEA)

norepinephrine uptake (IEA)

organic anion transport (ISO)

organic cation transport (IEA,ISO)

organic hydroxy compound transport (IEA,ISO)

quaternary ammonium group transport (IEA,ISO)

regulation of appetite (IEA,ISO)

serotonin transport (IEA)

serotonin uptake (IEA)

spermidine transport (ISO)

transmembrane transport (IEA)

xenobiotic transport (IEA)

Cellular Component

apical plasma membrane (IEA)

basolateral plasma membrane (IEA)

endomembrane system (IEA)

membrane (IEA)

mitochondrial membrane (IEA)

neuronal cell body (IEA)

plasma membrane (IEA)

presynapse (IEA)

Molecular Function

dopamine:sodium symporter activity (ISO)

monoamine transmembrane transporter activity (IEA)

neurotransmitter transmembrane transporter activity (IEA)

organic anion transmembrane transporter activity (ISO)

organic cation transmembrane transporter activity (IEA,ISO)

protein binding (ISO)

quaternary ammonium group transmembrane transporter activity (IEA,ISO)

spermidine transmembrane transporter activity (ISO)

toxin transmembrane transporter activity (IEA,ISO)

transmembrane transporter activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

lamivudine pharmacokinetics pathway (ISO)

metformin pharmacokinetics pathway (ISO)

References

Additional References at PubMed

PMID:14681463	PMID:17145712	PMID:22301074

Genomics

Comparative Map Data

SLC22A3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	7,110,074 - 7,207,401 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	7,105,486 - 7,207,395 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	8,787,403 - 8,885,452 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC22A3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	160,348,378 - 160,452,577 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	160,348,378 - 160,452,577 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	160,769,410 - 160,873,609 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	160,689,415 - 160,796,004 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	160,739,835 - 160,846,425	NCBI
Celera	6	161,420,905 - 161,527,486 (+)	NCBI		Celera
Cytogenetic Map	6	q25.3	NCBI
HuRef	6	158,244,012 - 158,348,214 (+)	NCBI		HuRef
CHM1_1	6	161,032,217 - 161,136,415 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	161,598,508 - 161,702,771 (+)	NCBI		T2T-CHM13v2.0

Slc22a3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	12,638,859 - 12,726,591 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	12,637,847 - 12,726,591 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	12,419,972 - 12,507,704 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	12,418,960 - 12,507,704 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	12,612,838 - 12,700,570 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	12,263,330 - 12,351,062 (-)	NCBI		MGSCv36	mm8
Celera	17	12,450,734 - 12,539,105 (-)	NCBI		Celera
Cytogenetic Map	17	A1	NCBI
cM Map	17	8.52	NCBI

Slc22a3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	50,783,218 - 50,872,358 (+)	NCBI		GRCr8
mRatBN7.2	1	48,235,476 - 48,324,617 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	48,235,476 - 48,324,612 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	48,927,055 - 49,016,211 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	54,912,824 - 55,001,976 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	49,002,573 - 49,091,712 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	48,433,079 - 48,521,261 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	48,433,079 - 48,521,256 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	51,234,467 - 51,321,364 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	42,690,158 - 42,781,895 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	42,693,102 - 42,784,835 (+)	NCBI
Celera	1	44,028,160 - 44,116,659 (+)	NCBI		Celera
Cytogenetic Map	1	q11	NCBI

Slc22a3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955439	20,367,333 - 20,476,891 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955439	20,367,324 - 20,476,891 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC22A3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	180,457,233 - 180,561,182 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	178,361,200 - 178,465,143 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	158,240,390 - 158,344,338 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	163,232,539 - 163,351,256 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	163,247,643 - 163,349,735 (+)	Ensembl	panpan1.1		panPan2

SLC22A3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	49,407,949 - 49,496,627 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	49,407,966 - 49,496,620 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	50,250,859 - 50,339,627 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	49,593,106 - 49,681,894 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	49,593,126 - 49,681,430 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	49,475,470 - 49,564,251 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	49,347,643 - 49,435,978 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	49,962,647 - 50,051,070 (+)	NCBI		UU_Cfam_GSD_1.0

Slc22a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	144,441,761 - 144,522,387 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936489	11,693,755 - 11,772,628 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936489	11,693,755 - 11,774,380 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC22A3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	87,971,305 - 88,076,468 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	87,971,392 - 88,074,946 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	60,348,130 - 60,452,975 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc22a3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624855	2,399,671 - 2,516,237 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624855	2,402,096 - 2,516,249 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in SLC22A3
5018 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system
10	4	21	3	4	14	12	21	3	6

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003121106	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021086250	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK397664	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EU475902	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FP085554	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000004467 ⟹ ENSSSCP00000004365

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	1	7,110,074 - 7,207,401 (-)	Ensembl

RefSeq Acc Id:

XM_003121106 ⟹ XP_003121154

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	1	7,110,070 - 7,207,395 (-)	NCBI

Sequence:

show sequence

ACTCGGAGGCCCGGGCGGCGGGCGGCCGGACGCGCTCGGGCAGTCGGCGGGCAGGCGGGCGGGC
GGGCGGCGCGCACCATGCCCTCCTTCGACGAGGCGCTGCAGCGGGCCGGCGAGTTCGGGCGCTT
CCAGCGGCGCGTGTTCCTGCTGCTGTGCCTGACGGGCGTCACCTTCGCCTTCCTCTTCGTCGGC
GTGGTCTTCCTGGGCAGCCAGCCCGACCACTACTGGTGCCGCGGGCCGAGCGCCACCGCGCTGG
CCGAGCGCTGCGGCTGGAGCCCGGAGGAGGAGTGGAACCGCACGGCGCCCGCCCGCCTCGGCCC
CGAGCCCCCCGAGCGCCGCGGCGACGGCCGCTGCCAGCGCTACCTCCTGGAGGCGGTCAACGCC
AGCGCCGCCGGCCCGGGCGCGCTCAGCTGCGCCGACCCGCTCGCCGCCTTCCCCAACCGCTCGG
CGCCGCTCGTGCCGTGCCGGGGCGGCTGGCGCTACGCCCAGGCCCACTCGACCATCATCAGCGA
GTTTGACCTCGTGTGTGACAATGCTTGGATGCTGGACCTCACACAAGCCATCCTCAACCTGGGC
TTCCTGGCTGGGGCGTTCACCTTGGGCTACGCAGCGGACAGGTACGGACGAATAGTCATTTACT
TAATATCCTGCCTCGGTGTTGGCGTCACCGGCGTTGTGGTGGCATTTGCACCCAATTTCCCTGT
GTTGGTGGTCTTCCGCTTCCTCCAAGGCGTGTTTGGAAAGGGAACATGGATGACATGCTACGTG
ATTGTGACGGAAATAGTAGGTTCGAAGCAAAGAAGGATTGTGGGAATAGTGATTCAAATGTTCT
TCACTCTTGGGATCATAATCCTCCCTGGAATTGCCTACTTTATCCCCAACTGGCAAGGGATCCA
GCTGGCCATCACGCTGCCCAACTTTCTCTTCCTGCTTTATTACTGGGCGGTCCCCGAATCTCCC
CGCTGGCTGGTTACTCGGAAGAAAGGAGATAGAGCCTTAAAAATTCTGAGGAGCATTGCCAAAT
GCAATGGGAAATATCTCTCGCCAAACTACACGGAGATCACTGTTACCGATGAGGAGGTTAGCAA
TCCATCCTTTTTAGATCTGGTGAGGACTCGCCAAATGAGGAAGTGCACGCTTATACTTATGTTT
GCTTGGTTCACGAGCGCTGTGGTGTATCAAGGACTCGTCATGCGCCTGGGAATTATAGGAGGCA
ACCTCTATATTGACTTTTTCATCTCGGGAGTTGTGGAACTGCCAGGAGCCCTCTTGATCCTATT
AACCATCGAGCGTTTCGGTCGACGCCTACCCTTTGCCGCAAGCAATATAGTGGCAGGAGTGGCA
TGCCTTGTCACTGCGTTCTTACCTGAAGGAATACCCTGGTTGAGAACCGCGGTGGCCACGCTGG
GAAGGCTGGGGATAACCATGGCCTTTGAGATTGTTTATTTGGTAAATTCAGAGTTGTACCCAAC
CACATTACGAAACTTTGGAGTTTCCCTCTGTTCAGGCTTATGTGACTTTGGGGGCATCATAGCC
CCCTTTCTGCTTTTCCGGCTAGCAGCCATTTGGCTGGAACTACCTCTTATCATCTTTGGTATCC
TGGCGTCCGTCTGCGGTGGTCTTGTGATGCTTTTGCCTGAAACCAAGGGTATTGCCTTGCCAGA
AACAGTGGATGATGTAGAAAAACTTGACAGTCCGTATTCCTGTAAATGTGGCAGGAAAAACACA
ACCCAAGTTTCGGGCTCTCACCTTTGAGGCCCCACCGGAGACGGAAGGATGAGTCTCTCCAGGC
AGCACCCCCCCCGCACCCCCTCCCCAGGAACCGACGTGCCTTTCAGAGACGCCTGTGTGTCCAT
TTCAGCTGCGCAGCTCCCAGTGTTTTTAATACTTTACAAAGACCTTCGGACTACCCAGAGTATT
TTTCTATGACGTGGGATGAATTAGGACTTACATGCTGTGGAAGTTTCTGGGAACATGTAACATG
CGGCTGGTTTAGCCAAGAGCCTGCTGCGAGCACAGCTCCTCTGGAGGTTTTTTCTCACTCGGGG
CGGTGTCTCCGACCCCGGGGTTACAGAGAGACGAGCAAAGCCCCGTCGAGATCTCATGACAGTT
CCATCAAGAGTGCAGGATGAGCGAACTGAGGATCCAGAAAGGACATCCCGAAATAGGTTCATCA
AACCTGATCAAGAAGCGGAGGCTCTGGTCTGCGTGACCTGAGGATTCCTGGCCGGAAGACCTGG
GAATCCTGTTAGTAAAAGGTTCTGACGCGAAGGGCCTGGGGCCACGTGGCTCCAAGCCTTGCTC
TCTGGTCTCCCCTGGAGCTCCGTCGGCACCCGGGGTCGCAGGCACCTTCAGCCTTGTTCCGTCA
GTAAGAACAAATCCGCTCTATGGTTCCAGGTGCTTGGATTTCTGACAGTGAACTTGAGGTCCTC
CTTTCCCGGCCACCTGGAGCCACAAACTCAGTTTTTGATGGGTGAACCCATGGATTAGGATCTC
GCAGGTCTTAGGATTTGACTCATAAAGGGATATTTATGTTCTGTTTGTGAGTTCTGTCCTGTGA
TAGGGCCCGTGGTCAGGAGTGAAAAAGATGGACGGACCCCATTCGATCCTGACACTTTTAACTT
GTCTTGGGAAGAAGCTTACATTTTAATTTAACAGAAGGGTTGATGCTACCCATGCTTAAAAGAA
TTAGCAGAAGCTTTGTAAATGCCTTTGTAAGTACTAATAAGGGATTTGATCTTTATTTTTTTGA
TACTGAGACTTTTTTTTTTTGTCTGTTTTTTTTTAGGGCTGCCCCCATGGCACATGGAGGTTCC
CAGGCTGGGGGTCAAATCGGAGCTGCAGGTGCCAGCCTATGCCACAGCCACAGCAATGCAGGAT
CCGAGCTGAGTCTGTGACGGACACCATAGCTCATGGCATCGCCGGATCCTTTACCTACTGAGGA
AGGCCAGGGATCGAACCCACATCCTCATGGATCCTAGTTGGGTTCACTACCACCGAGCCACAAT
GGGAATGCTATTACTGAGACTTTTGAAATGTGGAGTTTAAGTACACATATGCTGTCTTTATGAT
GGTCTGTGTTCTATATTTGTTACGCTTTCAGCTTCAGTGTGTATCTTAACACAGAATCGGGTAA
TGAATTGGTTTGGGTGGACACGCAAAATGGGAACCAAAGGAAAATCCTGCCAGTAAGGAAGAAA
ATTTCTATGTGAACACGTGGCGATGTATGCGGTGTACATGCTCATCATAAAGTACGTTTTCGGC
CCTTAAAGCGCATTGGGATGGAGTGTGAATGCTTTATTTTTCAATGAAATAAACACAGTCTTTG
AGGACGTGGGGCTGCATCCAGCCTCCCTCCACACTCACTTGCGTTCTGCTTCCTTTGCATTTCT
CTTTGCTGTGGAATGATGGTTGTTTGTTGATACTGTCACCTTTGAATTGTATTTTGAGGTGACA
TGTGGGGTTCTGACCACAATAAAAAAATGCACATGGTCAAGAGAAACCGATTTTCATCCTTTCT
CTTCCTTCTGAACCTGAGTGACTGTAAAACGATTTTGCCATGCGAATGAAGAGAGCGCCGCATA
CGTGGGCAGCCAGCTACGGCGGAAAGGAAGGGGCTGCCTTCGCCGTGTGTTCACGCCGCCTTGC
CAGGCTCTTGGTACCATCCCTAGACTCACGTGGGACCCAGAGTAACACGCAGCCTCCTGGCTGG
TCTTGTTTCTGTTTTGTTTTGTTCTTTTCTTTTTTTAATTAAAGTGTAGTTGATTTACAA

hide sequence

RefSeq Acc Id:

XM_021086250 ⟹ XP_020941909

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	1	7,105,486 - 7,207,388 (-)	NCBI

Sequence:

show sequence

GGCCCGGGCGGCGGGCGGCCGGACGCGCTCGGGCAGTCGGCGGGCAGGCGGGCGGGCGGGCGGC
GCGCACCATGCCCTCCTTCGACGAGGCGCTGCAGCGGGCCGGCGAGTTCGGGCGCTTCCAGCGG
CGCGTGTTCCTGCTGCTGTGCCTGACGGGCGTCACCTTCGCCTTCCTCTTCGTCGGCGTGGTCT
TCCTGGGCAGCCAGCCCGACCACTACTGGTGCCGCGGGCCGAGCGCCACCGCGCTGGCCGAGCG
CTGCGGCTGGAGCCCGGAGGAGGAGTGGAACCGCACGGCGCCCGCCCGCCTCGGCCCCGAGCCC
CCCGAGCGCCGCGGCGACGGCCGCTGCCAGCGCTACCTCCTGGAGGCGGTCAACGCCAGCGCCG
CCGGCCCGGGCGCGCTCAGCTGCGCCGACCCGCTCGCCGCCTTCCCCAACCGCTCGGCGCCGCT
CGTGCCGTGCCGGGGCGGCTGGCGCTACGCCCAGGCCCACTCGACCATCATCAGCGAGTTTGAC
CTCGTGTGTGACAATGCTTGGATGCTGGACCTCACACAAGCCATCCTCAACCTGGGCTTCCTGG
CTGGGGCGTTCACCTTGGGCTACGCAGCGGACAGGTACGGACGAATAGTCATTTACTTAATATC
CTGCCTCGGTGTTGGCGTCACCGGCGTTGTGGTGGCATTTGCACCCAATTTCCCTGTGTTGGTG
GTCTTCCGCTTCCTCCAAGGCGTGTTTGGAAAGGGAACATGGATGACATGCTACGTGATTGTGA
CGGAAATAGTAGGTTCGAAGCAAAGAAGGATTGTGGGAATAGTGATTCAAATGTTCTTCACTCT
TGGGATCATAATCCTCCCTGGAATTGCCTACTTTATCCCCAACTGGCAAGGGATCCAGCTGGCC
ATCACGCTGCCCAACTTTCTCTTCCTGCTTTATTACTGGGCGGTCCCCGAATCTCCCCGCTGGC
TGGTTACTCGGAAGAAAGGAGATAGAGCCTTAAAAATTCTGAGGAGCATTGCCAAATGCAATGG
GAAATATCTCTCGCCAAACTACACGGAGATCACTGTTACCGATGAGGAGGTTAGCAATCCATCC
TTTTTAGATCTGGTGAGGACTCGCCAAATGAGGAAGTGCACGCTTATACTTATGTTTGCTTGGT
TCACGAGCGCTGTGGTGTATCAAGGACTCGTCATGCGCCTGGGAATTATAGGAGGCAACCTCTA
TATTGACTTTTTCATCTCGGGAGTTGTGGAACTGCCAGGAGCCCTCTTGATCCTATTAACCATC
GAGCGTTTCGGTCGACGCCTACCCTTTGCCGCAAGCAATATAGTGGCAGGAGTGGCATGCCTTG
TCACTGCGTTCTTACCTGAAGGAATACCCTGGTTGAGAACCGCGGTGGCCACGCTGGGAAGGCT
GGGGATAACCATGGCCTTTGAGATTGTTTATTTGGTAAATTCAGAGTTGTACCCAACCACATTA
CGAAACTTTGGAGTTTCCCTCTGTTCAGGCTTATGTGACTTTGGGGGCATCATAGCCCCCTTTC
TGCTTTTCCGGCTAGCAGCCATTTGGCTGGAACTACCTCTTATCATCTTTGGTATCCTGGCGTC
CGTCTGCGGTGGTCTTGTGATGCTTTTGCCTGAAACCAAGGGTATTGCCTTGCCAGAAACAGTG
GATGATGTAGAAAAACTTGACAGGGACAGTGAACATTCATCTACGCGTTTATTTCACTCACTGT
ATTTCTTTTGTGTGTGAGGAAGAACTGCTTTCCCACTTTGGCAAATGGAAACAGAACCCTTGCA
AAATCACGAGGAGAAATGACGTCTTCCAGATGGACACACCCAGGTAGGTCGCAGTATGCTTTTC
ACACATAATCCAGTTTTCCGATTTTGCAAGCCCAGCTTTCACGGGTTTTGCAAAATGTCTGTCT
TGCCAGCATGGAACGGCCAAGAAAGAAGGTACCATTTCTCCTCCAGAGACTTTGCGTGAACTTG
CGTTTGGAAAACTTACCCTCCATCTGGAGTTGGCAGCAGCCCTAAGAGGAAAGGAGGGACTGTC
CCAGCGCTGGCTGCTTAGAGCCCCCGGGGGGGACGGTCCCGACCACAGAAGCACCGGCTGACAG
GTGTATTACTTGAATTGAGTGGCTAGGAGGAGGGAGCAGCCTTTCTCGAAGTTGGTTTTTGTTT
TCGTTTTTGTTTTTTGCTGAAAAGTAGTTTATTCAAGTATCTGGTTTTTAAATCTGCTTTCTGA
GCAAAGCAGACAATATGCTGATAGGGACAAATCCATTCGTGGAGGGGAAGTCCTTGTGGTCTGT
GCAGTGGTGCTGCCACCCCGTGGCCACAGTGGAGATGGCATTTCTAAGGGCCTCAGGTGCCCCA
GGTAACCTAGGGATGTGGTGGAGGGGAGGCAGAAGCAGGTCCCTGAAAGTGGCCAGCGATTGCT
GATGAAGGGCTGACCTGAAGGACCGCCTCGACATCAGCACCCCCTTGCTTTGGAATAGGGAAGT
CAGGGAACGTCTAGAGGCTGAAGGGGAGAATTGCGACCTCACAAAGGCAGGCCGAGGACCTTGA
TTCGATGGCACTACTGTGACGTACAGAAAATTAATAAACAGACTTGACTCCTATTTTGTGACTC
CTGGTCCAATGAATATATTGAGAATCATTTTCTCAGTTAGACATTCAGATGAGGCCTGGAGAGC
CGGGGGGGCCTGCTGCAGGCTGGTGTTCAGAGACGTGTGGGTGGCCGGTGAGACAGACGAAAGA
GTGAATGGGCTTGGGGGCATCTGGCAGGCCTGGGTTTCATCAGGGCTCAGCTACACATGGGCTT
TGTGATGTCTGCTGATGATAGTGACAGCAGTGGGGGGGGGTTGATCATGATGGTGAAGATGATG
ATGATGTGGTGATGTGATGATGGTGATGATGTGGTGAGGATGGTGGTGGTGATGGTGGTGGTGG
GGTGATGATGGTGGAGATGATGTGGTGAAGATGGTGGTGGTGATGATGGTGTAAAGTTGAAGAC
GATGGTGATGATGGGGATCGTGATGACCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003121154	(Get FASTA)	NCBI Sequence Viewer
	XP_020941909	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ACA42547	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000004365
	ENSSSCP00000004365.2
	ENSSSCP00025026509.1
	ENSSSCP00030032358.1
	ENSSSCP00035033849.1
	ENSSSCP00035033859.1
	ENSSSCP00040008746.1
	ENSSSCP00045019740.1
	ENSSSCP00050001950.1
	ENSSSCP00050001968.1
	ENSSSCP00055017592.1
	ENSSSCP00055017621.1
	ENSSSCP00060012595.1
	ENSSSCP00065028060.1
	ENSSSCP00070045869.1
	ENSSSCP00070045870.1

RefSeq Acc Id:	XP_020941909 ⟸ XM_021086250
- Peptide Label:	isoform X2
- UniProtKB:	A0A8D1JJY9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPSFDEALQRAGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGSQPDHYWCRGPSATALAERCG WSPEEEWNRTAPARLGPEPPERRGDGRCQRYLLEAVNASAAGPGALSCADPLAAFPNRSAPLVP CRGGWRYAQAHSTIISEFDLVCDNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRIVIYLISCL GVGVTGVVVAFAPNFPVLVVFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGI IILPGIAYFIPNWQGIQLAITLPNFLFLLYYWAVPESPRWLVTRKKGDRALKILRSIAKCNGKY LSPNYTEITVTDEEVSNPSFLDLVRTRQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYID FFISGVVELPGALLILLTIERFGRRLPFAASNIVAGVACLVTAFLPEGIPWLRTAVATLGRLGI TMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAIWLELPLIIFGILASVC GGLVMLLPETKGIALPETVDDVEKLDRDSEHSSTRLFHSLYFFCV hide sequence

RefSeq Acc Id:	XP_003121154 ⟸ XM_003121106
- Peptide Label:	isoform X1
- UniProtKB:	F1SB80 (UniProtKB/TrEMBL), A0A4X1VVG5 (UniProtKB/TrEMBL), A0A8D1HLA9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPSFDEALQRAGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGSQPDHYWCRGPSATALAERCG WSPEEEWNRTAPARLGPEPPERRGDGRCQRYLLEAVNASAAGPGALSCADPLAAFPNRSAPLVP CRGGWRYAQAHSTIISEFDLVCDNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRIVIYLISCL GVGVTGVVVAFAPNFPVLVVFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGI IILPGIAYFIPNWQGIQLAITLPNFLFLLYYWAVPESPRWLVTRKKGDRALKILRSIAKCNGKY LSPNYTEITVTDEEVSNPSFLDLVRTRQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYID FFISGVVELPGALLILLTIERFGRRLPFAASNIVAGVACLVTAFLPEGIPWLRTAVATLGRLGI TMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAIWLELPLIIFGILASVC GGLVMLLPETKGIALPETVDDVEKLDSPYSCKCGRKNTTQVSGSHL hide sequence

Ensembl Acc Id:

ENSSSCP00000004365 ⟸ ENSSSCT00000004467

Protein Domains

Major facilitator superfamily (MFS) profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000004039	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00025045946	UniProtKB/TrEMBL
	ENSSSCG00030050905	UniProtKB/TrEMBL
	ENSSSCG00035060874	UniProtKB/TrEMBL
	ENSSSCG00040015448	UniProtKB/TrEMBL
	ENSSSCG00045016809	UniProtKB/TrEMBL
	ENSSSCG00050003566	UniProtKB/TrEMBL
	ENSSSCG00055011308	UniProtKB/TrEMBL
	ENSSSCG00060021663	UniProtKB/TrEMBL
	ENSSSCG00065047340	UniProtKB/TrEMBL
	ENSSSCG00070026982	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000004467	ENTREZGENE
	ENSSSCT00000004467.5	UniProtKB/TrEMBL
	ENSSSCT00025062400.1	UniProtKB/TrEMBL
	ENSSSCT00030070925.1	UniProtKB/TrEMBL
	ENSSSCT00035081742.1	UniProtKB/TrEMBL
	ENSSSCT00035081757.1	UniProtKB/TrEMBL
	ENSSSCT00040020815.1	UniProtKB/TrEMBL
	ENSSSCT00045028552.1	UniProtKB/TrEMBL
	ENSSSCT00050004805.1	UniProtKB/TrEMBL
	ENSSSCT00050004842.1	UniProtKB/TrEMBL
	ENSSSCT00055022201.1	UniProtKB/TrEMBL
	ENSSSCT00055022234.1	UniProtKB/TrEMBL
	ENSSSCT00060029371.1	UniProtKB/TrEMBL
	ENSSSCT00065064748.1	UniProtKB/TrEMBL
	ENSSSCT00070054106.1	UniProtKB/TrEMBL
	ENSSSCT00070054107.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1250.20	UniProtKB/TrEMBL
InterPro	MFS	UniProtKB/TrEMBL
	MFS_dom	UniProtKB/TrEMBL
	MFS_sugar_transport-like	UniProtKB/TrEMBL
	MFS_trans_sf	UniProtKB/TrEMBL
	Orgcat_transp/SVOP	UniProtKB/TrEMBL
	Sugar_transporter_CS	UniProtKB/TrEMBL
KEGG Report	ssc:100142677	UniProtKB/TrEMBL
NCBI Gene	SLC22A3	ENTREZGENE
PANTHER	SOLUTE CARRIER FAMILY 22 MEMBER	UniProtKB/TrEMBL
	SOLUTE CARRIER FAMILY 22 MEMBER 3	UniProtKB/TrEMBL
Pfam	MFS_1	UniProtKB/TrEMBL
	Sugar_tr	UniProtKB/TrEMBL
PROSITE	MFS	UniProtKB/TrEMBL
	SUGAR_TRANSPORT_1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF103473	UniProtKB/TrEMBL
UniProt	A0A4X1VVG5	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1VW68_PIG	UniProtKB/TrEMBL
	A0A8D1HLA9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1JJY9	ENTREZGENE, UniProtKB/TrEMBL
	B1PM34_PIG	UniProtKB/TrEMBL
	F1SB80	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:92980	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Annotations - SMPDB