RYR1 (ryanodine receptor 1) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: RYR1 (ryanodine receptor 1) Sus scrofa
Analyze
Symbol: RYR1
Name: ryanodine receptor 1
RGD ID: 14000791
Description: ENCODES a protein that exhibits ATP binding (ortholog); calcium channel activity (ortholog); calcium ion binding (ortholog); INVOLVED IN calcium ion transmembrane transport (ortholog); calcium ion transport (ortholog); cellular response to ATP (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH ankyloglossia (ortholog); Arthrogryposis (ortholog); arthrogryposis due to muscular dystrophy (ortholog); FOUND IN cell cortex (ortholog); cytoplasm (ortholog); extrinsic component of cytoplasmic side of plasma membrane (ortholog); INTERACTS WITH caffeine; calcium atom; calcium(0)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: calcium release channel (ryanodine receptor 1); CRC; CRC1, RYR1; halothane; porcine stress syndrome; RYR; RYR-1; skeletal muscle calcium release channel; skeletal muscle ryanodine receptor; skeletal muscle-type ryanodine receptor; type 1 ryanodine receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1647,339,759 - 47,458,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2642,840,240 - 42,960,110 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap6q1.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:1312025   PMID:1329581   PMID:1862346   PMID:2174405   PMID:7989322   PMID:8220422   PMID:8220423   PMID:8288238   PMID:8617743   PMID:8835535   PMID:8930069   PMID:12376096  
PMID:15628869   PMID:16060492   PMID:17023049   PMID:17107340   PMID:17202397   PMID:18505726   PMID:19332786   PMID:19674865   PMID:20815817   PMID:22022376   PMID:24176615   PMID:27033913  


Genomics

Comparative Map Data
RYR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1647,339,759 - 47,458,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2642,840,240 - 42,960,110 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap6q1.2NCBI
RYR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1938,433,691 - 38,587,564 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1938,433,699 - 38,587,564 (+)EnsemblGRCh38hg38GRCh38
GRCh381938,433,691 - 38,587,564 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371938,924,340 - 39,078,204 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361943,616,180 - 43,770,044 (+)NCBINCBI36hg18NCBI36
Build 341943,616,179 - 43,770,012NCBI
Celera1935,726,452 - 35,880,238 (+)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1935,371,495 - 35,526,332 (+)NCBIHuRef
CHM1_11938,924,701 - 39,079,134 (+)NCBICHM1_1
Ryr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39728,702,765 - 28,824,599 (-)NCBIGRCm39mm39
GRCm38729,003,340 - 29,125,179 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl729,003,344 - 29,125,179 (-)EnsemblGRCm38mm10GRCm38
MGSCv37729,788,359 - 29,910,170 (-)NCBIGRCm37mm9NCBIm37
MGSCv36728,712,104 - 28,833,911 (-)NCBImm8
Celera723,565,768 - 23,695,212 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map716.94NCBI
Ryr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0187,959,596 - 88,066,252 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl187,959,712 - 88,066,101 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0189,135,622 - 89,241,311 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4184,116,098 - 84,254,503 (-)NCBIRGSC3.4rn4RGSC3.4
Celera178,682,691 - 78,812,242 (-)NCBICelera
Cytogenetic Map1q21NCBI
Ryr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955468879,951 - 1,000,036 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955468879,807 - 1,000,118 (-)NCBIChiLan1.0ChiLan1.0
RYR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11944,099,196 - 44,256,470 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1944,106,036 - 44,256,327 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01935,527,466 - 35,685,446 (+)NCBIMhudiblu_PPA_v0panPan3
RYR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1114,461,348 - 114,579,493 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11114,461,350 - 114,579,577 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ryr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049368011,185,615 - 1,298,416 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RYR1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1633,080,443 - 33,234,478 (+)NCBI
ChlSab1.1 Ensembl633,080,758 - 33,213,788 (+)Ensembl
Ryr1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462479411,888,211 - 12,004,457 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001001534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FP102670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01124864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM747957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JF303704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JF303705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M32501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M91451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M91452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M91456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U15965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X62880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X65498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X65499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X65500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X65501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X65502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X65503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X65504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X68247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X69465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z15155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z49778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z54280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: NM_001001534   ⟹   NP_001001534
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1647,339,759 - 47,458,457 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001001534   ⟸   NM_001001534
- UniProtKB: Q29105 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
B30.2/SPRY   EF-hand   MIR   RYDR_ITPR


Additional Information

Database Acc Id Source(s)
Gene3D-CATH 2.60.120.920 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ins145_P3_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIH_assoc-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ryan_recept UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ryanodine_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ryanrecept_TM4-6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RyR/IP3R_RIH_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RyR1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY1_RyR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY2_RyR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY3_RyR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:396718 UniProtKB/TrEMBL
NCBI Gene RYR1 ENTREZGENE
PANTHER PTHR13715:SF15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ins145_P3_rec UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIH_assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RR_TM4-6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RYDR_ITPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RyR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS RYANODINER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF100909 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49899 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF82109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Ssc.8 ENTREZGENE
UniProt P16960 ENTREZGENE
  Q29104_PIG UniProtKB/TrEMBL
  Q29105 ENTREZGENE, UniProtKB/TrEMBL
  Q6LDG1_PIG UniProtKB/TrEMBL
  RYR1_PIG UniProtKB/Swiss-Prot