FGG (fibrinogen gamma chain) - Rat Genome Database

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Gene: FGG (fibrinogen gamma chain) Sus scrofa
Analyze
Symbol: FGG
Name: fibrinogen gamma chain
RGD ID: 13976603
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cellular response to interleukin-1 (ortholog); cellular response to interleukin-6 (ortholog); platelet maturation (ortholog); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; ASSOCIATED WITH blood coagulation disease (ortholog); brain small vessel disease (ortholog); congenital afibrinogenemia (ortholog); FOUND IN blood microparticle (ortholog); cell cortex (ortholog); synapse (ortholog); INTERACTS WITH ammonia
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: fibrinogen; fibrinogen gamma polypeptide
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl874,553,105 - 74,563,688 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1874,553,040 - 74,562,151 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2878,850,804 - 78,859,881 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
ammonia  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:9883527   PMID:14681463   PMID:15679890   PMID:17407547   PMID:21327301   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FGG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl874,553,105 - 74,563,688 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1874,553,040 - 74,562,151 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2878,850,804 - 78,859,881 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FGG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384154,604,136 - 154,612,656 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4154,604,134 - 154,612,967 (-)EnsemblGRCh38hg38GRCh38
GRCh374155,525,288 - 155,533,808 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364155,744,736 - 155,753,352 (-)NCBINCBI36Build 36hg18NCBI36
Build 344155,883,339 - 155,891,408NCBI
Celera4152,856,249 - 152,864,865 (-)NCBICelera
Cytogenetic Map4q32.1NCBI
HuRef4151,265,862 - 151,274,478 (-)NCBIHuRef
CHM1_14155,503,216 - 155,511,832 (-)NCBICHM1_1
T2T-CHM13v2.04157,935,943 - 157,944,463 (-)NCBIT2T-CHM13v2.0
Fgg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39382,915,031 - 82,922,363 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl382,915,031 - 82,922,356 (+)EnsemblGRCm39 Ensembl
GRCm38383,007,724 - 83,015,056 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl383,007,724 - 83,015,049 (+)EnsemblGRCm38mm10GRCm38
MGSCv37382,811,818 - 82,818,971 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36383,093,823 - 83,100,976 (+)NCBIMGSCv36mm8
Celera383,011,995 - 83,019,099 (+)NCBICelera
Cytogenetic Map3E3NCBI
cM Map336.94NCBI
Fgg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82170,652,929 - 170,660,372 (+)NCBIGRCr8
mRatBN7.22168,354,880 - 168,362,325 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2168,355,013 - 168,362,322 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2175,545,169 - 175,552,469 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02173,566,102 - 173,573,404 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02168,167,520 - 168,174,818 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02181,987,080 - 181,994,523 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2181,987,217 - 181,994,514 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02201,401,700 - 201,409,143 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42174,727,312 - 174,734,594 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12174,677,417 - 174,684,698 (+)NCBI
Celera2162,381,731 - 162,389,018 (+)NCBICelera
Cytogenetic Map2q34NCBI
Fgg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554718,786,910 - 8,795,013 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554718,786,910 - 8,794,947 (+)NCBIChiLan1.0ChiLan1.0
FGG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23152,516,571 - 152,539,442 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14152,872,009 - 152,886,596 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04146,970,671 - 146,979,348 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14158,788,761 - 158,797,460 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4158,788,966 - 158,797,237 (-)Ensemblpanpan1.1panPan2
FGG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11552,261,215 - 52,270,077 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1552,261,217 - 52,269,964 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1552,605,731 - 52,614,513 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01552,948,278 - 52,957,065 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1552,948,283 - 52,957,026 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11552,203,172 - 52,211,960 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01552,307,741 - 52,316,537 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01552,622,568 - 52,631,351 (-)NCBIUU_Cfam_GSD_1.0
Fgg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530138,194,766 - 38,203,257 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365761,343,661 - 1,352,143 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365761,343,657 - 1,352,085 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17101,148,457 - 101,157,245 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7101,148,058 - 101,157,111 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603780,803,057 - 80,811,786 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248585,827,316 - 5,838,170 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248585,828,334 - 5,836,382 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FGG
255 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
8 3 3 3 8 2 3

Sequence


Ensembl Acc Id: ENSSSCT00000009856   ⟹   ENSSSCP00000009603
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl874,553,105 - 74,561,411 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000026223   ⟹   ENSSSCP00000024374
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl874,553,254 - 74,563,688 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000069628   ⟹   ENSSSCP00000068731
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl874,553,105 - 74,561,939 (+)Ensembl
RefSeq Acc Id: NM_001244524   ⟹   NP_001231453
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1874,553,105 - 74,562,151 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005666793   ⟹   XP_005666850
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1874,553,040 - 74,562,102 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005666850   ⟸   XM_005666793
- Peptide Label: isoform X1
- UniProtKB: F1RX35 (UniProtKB/TrEMBL),   A0A8D1U5L7 (UniProtKB/TrEMBL),   I3LJW2 (UniProtKB/TrEMBL),   A0A8D0SAB4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001231453   ⟸   NM_001244524
- Peptide Label: precursor
- UniProtKB: A0A8D1I1I0 (UniProtKB/TrEMBL),   A0A8D1F8J7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000009603   ⟸   ENSSSCT00000009856
Ensembl Acc Id: ENSSSCP00000024374   ⟸   ENSSSCT00000026223
Ensembl Acc Id: ENSSSCP00000068731   ⟸   ENSSSCT00000069628
Protein Domains
Fibrinogen C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000024314 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015048748 UniProtKB/TrEMBL
  ENSSSCG00025049250 UniProtKB/TrEMBL
  ENSSSCG00030014429 UniProtKB/TrEMBL
  ENSSSCG00035021813 UniProtKB/TrEMBL
  ENSSSCG00040054074 UniProtKB/TrEMBL
  ENSSSCG00045023515 UniProtKB/TrEMBL
  ENSSSCG00050003108 UniProtKB/TrEMBL
  ENSSSCG00055018501 UniProtKB/TrEMBL
  ENSSSCG00060037577 UniProtKB/TrEMBL
  ENSSSCG00065058309 UniProtKB/TrEMBL
  ENSSSCG00070003780 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000009856.4 UniProtKB/TrEMBL
  ENSSSCT00000026223 ENTREZGENE
  ENSSSCT00000026223.4 UniProtKB/TrEMBL
  ENSSSCT00000069628 ENTREZGENE
  ENSSSCT00000069628.2 UniProtKB/TrEMBL
  ENSSSCT00015064860.1 UniProtKB/TrEMBL
  ENSSSCT00015065052.1 UniProtKB/TrEMBL
  ENSSSCT00025067117.1 UniProtKB/TrEMBL
  ENSSSCT00025067293.1 UniProtKB/TrEMBL
  ENSSSCT00030019865.1 UniProtKB/TrEMBL
  ENSSSCT00030019885.1 UniProtKB/TrEMBL
  ENSSSCT00035028453.1 UniProtKB/TrEMBL
  ENSSSCT00035028460.1 UniProtKB/TrEMBL
  ENSSSCT00040073148.1 UniProtKB/TrEMBL
  ENSSSCT00040073256.1 UniProtKB/TrEMBL
  ENSSSCT00045040188.1 UniProtKB/TrEMBL
  ENSSSCT00045040299.1 UniProtKB/TrEMBL
  ENSSSCT00045040406.1 UniProtKB/TrEMBL
  ENSSSCT00050004053.1 UniProtKB/TrEMBL
  ENSSSCT00050004068.1 UniProtKB/TrEMBL
  ENSSSCT00055036187.1 UniProtKB/TrEMBL
  ENSSSCT00055036267.1 UniProtKB/TrEMBL
  ENSSSCT00055036355.1 UniProtKB/TrEMBL
  ENSSSCT00060050845.1 UniProtKB/TrEMBL
  ENSSSCT00060050855.1 UniProtKB/TrEMBL
  ENSSSCT00065079809.1 UniProtKB/TrEMBL
  ENSSSCT00070007089.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.50 UniProtKB/TrEMBL
  3.90.215.10 UniProtKB/TrEMBL
  Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 UniProtKB/TrEMBL
InterPro Fibrinogen UniProtKB/TrEMBL
  Fibrinogen-like_C UniProtKB/TrEMBL
  Fibrinogen_a/b/g_C_1 UniProtKB/TrEMBL
  Fibrinogen_a/b/g_C_dom UniProtKB/TrEMBL
  Fibrinogen_a/b/g_coil_dom UniProtKB/TrEMBL
  Fibrinogen_CS UniProtKB/TrEMBL
KEGG Report ssc:403164 UniProtKB/TrEMBL
NCBI Gene FGG ENTREZGENE
PANTHER FIBRINOGEN ALPHA CHAIN UniProtKB/TrEMBL
  FIBRINOGEN ALPHA CHAIN UniProtKB/TrEMBL
Pfam Fib_alpha UniProtKB/TrEMBL
  Fibrinogen_C UniProtKB/TrEMBL
PROSITE FIBRINOGEN_C_1 UniProtKB/TrEMBL
  FIBRINOGEN_C_2 UniProtKB/TrEMBL
SMART FBG UniProtKB/TrEMBL
  Fib_alpha UniProtKB/TrEMBL
Superfamily-SCOP Fibrinogen coiled-coil and central regions UniProtKB/TrEMBL
  SSF56496 UniProtKB/TrEMBL
UniProt A0A5G2QUU1_PIG UniProtKB/TrEMBL
  A0A8D0SAB4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1F8J7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1I1I0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1U5L7 ENTREZGENE, UniProtKB/TrEMBL
  F1RX35 ENTREZGENE, UniProtKB/TrEMBL
  I3LJW2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:88122 ENTREZGENE