FGG (fibrinogen gamma chain) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: FGG (fibrinogen gamma chain) Canis lupus familiaris
Analyze
Symbol: FGG
Name: fibrinogen gamma chain
RGD ID: 12333033
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cellular response to interleukin-1 (ortholog); cellular response to interleukin-6 (ortholog); platelet maturation (ortholog); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; ASSOCIATED WITH blood coagulation disease (ortholog); brain small vessel disease (ortholog); congenital afibrinogenemia (ortholog); FOUND IN blood microparticle (ortholog); cell cortex (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11552,261,215 - 52,270,077 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1552,261,217 - 52,269,964 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1552,605,731 - 52,614,513 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01552,948,278 - 52,957,065 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1552,948,283 - 52,957,026 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11552,203,172 - 52,211,960 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01552,307,741 - 52,316,537 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01552,622,568 - 52,631,351 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FGG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11552,261,215 - 52,270,077 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1552,261,217 - 52,269,964 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1552,605,731 - 52,614,513 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01552,948,278 - 52,957,065 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1552,948,283 - 52,957,026 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11552,203,172 - 52,211,960 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01552,307,741 - 52,316,537 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01552,622,568 - 52,631,351 (-)NCBIUU_Cfam_GSD_1.0
FGG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384154,604,136 - 154,612,656 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4154,604,134 - 154,612,967 (-)EnsemblGRCh38hg38GRCh38
GRCh374155,525,288 - 155,533,808 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364155,744,736 - 155,753,352 (-)NCBINCBI36Build 36hg18NCBI36
Build 344155,883,339 - 155,891,408NCBI
Celera4152,856,249 - 152,864,865 (-)NCBICelera
Cytogenetic Map4q32.1NCBI
HuRef4151,265,862 - 151,274,478 (-)NCBIHuRef
CHM1_14155,503,216 - 155,511,832 (-)NCBICHM1_1
T2T-CHM13v2.04157,935,943 - 157,944,463 (-)NCBIT2T-CHM13v2.0
Fgg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39382,915,031 - 82,922,363 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl382,915,031 - 82,922,356 (+)EnsemblGRCm39 Ensembl
GRCm38383,007,724 - 83,015,056 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl383,007,724 - 83,015,049 (+)EnsemblGRCm38mm10GRCm38
MGSCv37382,811,818 - 82,818,971 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36383,093,823 - 83,100,976 (+)NCBIMGSCv36mm8
Celera383,011,995 - 83,019,099 (+)NCBICelera
Cytogenetic Map3E3NCBI
cM Map336.94NCBI
Fgg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82170,652,929 - 170,660,372 (+)NCBIGRCr8
mRatBN7.22168,354,880 - 168,362,325 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2168,355,013 - 168,362,322 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2175,545,169 - 175,552,469 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02173,566,102 - 173,573,404 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02168,167,520 - 168,174,818 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02181,987,080 - 181,994,523 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2181,987,217 - 181,994,514 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02201,401,700 - 201,409,143 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42174,727,312 - 174,734,594 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12174,677,417 - 174,684,698 (+)NCBI
Celera2162,381,731 - 162,389,018 (+)NCBICelera
Cytogenetic Map2q34NCBI
Fgg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554718,786,910 - 8,795,013 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554718,786,910 - 8,794,947 (+)NCBIChiLan1.0ChiLan1.0
FGG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23152,516,571 - 152,539,442 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14152,872,009 - 152,886,596 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04146,970,671 - 146,979,348 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14158,788,761 - 158,797,460 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4158,788,966 - 158,797,237 (-)Ensemblpanpan1.1panPan2
Fgg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530138,194,766 - 38,203,257 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365761,343,661 - 1,352,143 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365761,343,657 - 1,352,085 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl874,553,105 - 74,563,688 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1874,553,040 - 74,562,151 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2878,850,804 - 78,859,881 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FGG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17101,148,457 - 101,157,245 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7101,148,058 - 101,157,111 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603780,803,057 - 80,811,786 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248585,827,316 - 5,838,170 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248585,828,334 - 5,836,382 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FGG
222 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 6 6 6
Medium 3 1
Low 3 1 1 1 2 3
Below cutoff 4 5 9 2 4 2 11 8 7 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000013420   ⟹   ENSCAFP00000012417
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1552,261,217 - 52,269,964 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845017343   ⟹   ENSCAFP00845013510
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1552,948,283 - 52,957,026 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845017402   ⟹   ENSCAFP00845013550
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1552,948,615 - 52,957,023 (-)Ensembl
RefSeq Acc Id: XM_005629368   ⟹   XP_005629425
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11552,261,632 - 52,270,077 (-)NCBI
Dog10K_Boxer_Tasha1552,606,052 - 52,614,513 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038496681   ⟹   XP_038352609
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11552,203,493 - 52,211,960 (-)NCBI
RefSeq Acc Id: XM_038496682   ⟹   XP_038352610
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11552,203,172 - 52,211,960 (-)NCBI
RefSeq Acc Id: XM_038559076   ⟹   XP_038415004
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01552,622,889 - 52,631,351 (-)NCBI
RefSeq Acc Id: XM_038559077   ⟹   XP_038415005
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01552,622,568 - 52,631,351 (-)NCBI
RefSeq Acc Id: XM_038623010   ⟹   XP_038478938
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01552,308,062 - 52,316,537 (-)NCBI
RefSeq Acc Id: XM_038623011   ⟹   XP_038478939
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01552,307,741 - 52,316,537 (-)NCBI
RefSeq Acc Id: XM_038688684   ⟹   XP_038544612
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01552,948,599 - 52,957,065 (-)NCBI
RefSeq Acc Id: XM_038688685   ⟹   XP_038544613
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01552,948,278 - 52,957,065 (-)NCBI
RefSeq Acc Id: XM_532698   ⟹   XP_532698
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11552,261,215 - 52,270,075 (-)NCBI
Dog10K_Boxer_Tasha1552,605,731 - 52,614,513 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_532698   ⟸   XM_532698
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SFJ2 (UniProtKB/TrEMBL),   A0A8I3N8Y1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005629425   ⟸   XM_005629368
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QTZ3 (UniProtKB/TrEMBL),   A0A8I3NPH9 (UniProtKB/TrEMBL),   A0A8P0TNR1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000012417   ⟸   ENSCAFT00000013420
RefSeq Acc Id: XP_038352610   ⟸   XM_038496682
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038352609   ⟸   XM_038496681
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038478939   ⟸   XM_038623011
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038478938   ⟸   XM_038623010
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038544613   ⟸   XM_038688685
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SFJ2 (UniProtKB/TrEMBL),   A0A8I3N8Y1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038544612   ⟸   XM_038688684
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QTZ3 (UniProtKB/TrEMBL),   A0A8I3NPH9 (UniProtKB/TrEMBL),   A0A8P0TNR1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038415005   ⟸   XM_038559077
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SFJ2 (UniProtKB/TrEMBL),   A0A8I3N8Y1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038415004   ⟸   XM_038559076
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QTZ3 (UniProtKB/TrEMBL),   A0A8I3NPH9 (UniProtKB/TrEMBL),   A0A8P0TNR1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845013550   ⟸   ENSCAFT00845017402
RefSeq Acc Id: ENSCAFP00845013510   ⟸   ENSCAFT00845017343
Protein Domains
Fibrinogen C-terminal

Promoters
RGD ID:13686008
Promoter ID:EPDNEW_C4074
Type:multiple initiation site
Name:FGG_1
Description:fibrinogen gamma chain
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11552,269,966 - 52,270,026EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000008440 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030008558 UniProtKB/TrEMBL
  ENSCAFG00040012843 UniProtKB/TrEMBL
  ENSCAFG00845009858 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000013420.5 UniProtKB/TrEMBL
  ENSCAFT00000104948.1 UniProtKB/TrEMBL
  ENSCAFT00030015734.1 UniProtKB/TrEMBL
  ENSCAFT00040023700.1 UniProtKB/TrEMBL
  ENSCAFT00845017343 ENTREZGENE
  ENSCAFT00845017343.1 UniProtKB/TrEMBL
  ENSCAFT00845017402 ENTREZGENE
  ENSCAFT00845017402.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.215.10 UniProtKB/TrEMBL
  Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 UniProtKB/TrEMBL
InterPro Fibrinogen UniProtKB/TrEMBL
  Fibrinogen-like_C UniProtKB/TrEMBL
  Fibrinogen_a/b/g_C_1 UniProtKB/TrEMBL
  Fibrinogen_a/b/g_C_dom UniProtKB/TrEMBL
  Fibrinogen_a/b/g_coil_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fibrinogen_CS UniProtKB/TrEMBL
KEGG Report cfa:475474 UniProtKB/TrEMBL
NCBI Gene FGG ENTREZGENE
PANTHER FIBRINOGEN ALPHA CHAIN UniProtKB/TrEMBL
  FIBRINOGEN GAMMA CHAIN UniProtKB/TrEMBL
Pfam Fib_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fibrinogen_C UniProtKB/TrEMBL
PROSITE FIBRINOGEN_C_1 UniProtKB/TrEMBL
  FIBRINOGEN_C_2 UniProtKB/TrEMBL
SMART FBG UniProtKB/TrEMBL
  Fib_alpha UniProtKB/TrEMBL
Superfamily-SCOP Fibrinogen coiled-coil and central regions UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56496 UniProtKB/TrEMBL
UniProt A0A8C0QTZ3 ENTREZGENE
  A0A8C0SFJ2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N8Y1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NPH9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TNR1 ENTREZGENE, UniProtKB/TrEMBL
  FIBG_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:54208 ENTREZGENE