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Gene: SREBF2 (sterol regulatory element binding transcription factor 2) Sus scrofa
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Symbol: SREBF2
Name: sterol regulatory element binding transcription factor 2
RGD ID: 14245787
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN aging (ortholog); positive regulation of cholesterol biosynthetic process (ortholog); positive regulation of protein targeting to mitochondrion (ortholog); PARTICIPATES IN altered p53 signaling pathway; sterol regulatory element-binding protein signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); carotid artery disease (ortholog); cholelithiasis (ortholog); FOUND IN cytoplasm (ortholog); dendrite (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH ezetimibe; simvastatin
Type: protein-coding
RefSeq Status: MODEL
Also known as: SREBP-2; sterol regulatory element binding protein 2; sterol regulatory element-binding protein 2
Orthologs:
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl56,719,487 - 6,784,672 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.156,719,484 - 6,784,724 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on SREBF2
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 14245787
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2020-07-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.