KDSR (3-ketodihydrosphingosine reductase) - Rat Genome Database

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Gene: KDSR (3-ketodihydrosphingosine reductase) Sus scrofa
Analyze
Symbol: KDSR
Name: 3-ketodihydrosphingosine reductase
RGD ID: 14081103
Description: ENCODES a protein that exhibits BH domain binding (ortholog); BH3 domain binding (ortholog); channel activity (ortholog); INVOLVED IN actin filament organization (ortholog); aging (ortholog); animal organ morphogenesis (ortholog); PARTICIPATES IN ceramide signaling pathway; erythropoietin signaling pathway; interleukin-2 signaling pathway; ASSOCIATED WITH abdominal obesity-metabolic syndrome 1 (ortholog); acute kidney failure (ortholog); Acute Lung Injury (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH (S)-nicotine; 3-oxalomalic acid; ATP
Type: protein-coding
RefSeq Status: MODEL
Also known as: apoptosis regulator Bcl-2; B-cell CLL/lymphoma 2; BCL2; BCL2 apoptosis regulator
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1158,288,544 - 158,518,879 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11158,337,403 - 158,518,214 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21175,824,218 - 175,994,403 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal obesity-metabolic syndrome 1  (ISO)
acute kidney failure  (ISO)
Acute Lung Injury  (ISO)
acute lymphoblastic leukemia  (ISO)
acute myeloid leukemia  (ISO)
adenocarcinoma  (ISO)
adenoma  (ISO)
Adrenal Insufficiency  (ISO)
AIDS-Related Kaposi Sarcoma  (ISO)
alcoholic liver cirrhosis  (ISO)
allergic contact dermatitis  (ISO)
allergic rhinitis  (ISO)
Alzheimer's disease  (ISO)
amyotrophic lateral sclerosis  (ISO)
anti-basement membrane glomerulonephritis  (ISO)
asthma  (ISO)
autistic disorder  (ISO)
azoospermia  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
B-Cell CLL/Lymphoma 2  (ISO)
bilirubin metabolic disorder  (ISO)
brain glioma  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
Breast Neoplasms  (ISO)
Burns  (ISO)
carcinoma  (ISO)
Cerebral Hemorrhage  (ISO)
cervix uteri carcinoma in situ  (ISO)
chromosome 18q deletion syndrome  (ISO)
Chronic Intermittent Hypoxia  (ISO)
clear cell adenocarcinoma  (ISO)
colon adenocarcinoma  (ISO)
colon cancer  (ISO)
Colonic Neoplasms  (ISO)
Colorectal Neoplasms  (ISO)
congestive heart failure  (ISO)
contact dermatitis  (ISO)
dementia  (ISO)
Diabetic Cardiomyopathies  (ISO)
diffuse large B-cell lymphoma  (ISO)
dilated cardiomyopathy  (ISO)
Disease Progression  (ISO)
ductal carcinoma in situ  (ISO)
end stage renal disease  (ISO)
Endometrial Neoplasms  (ISO)
endometriosis  (ISO)
Endotoxemia  (ISO)
Esophageal Neoplasms  (ISO)
esophagus adenocarcinoma  (ISO)
Experimental Allergic Asthma  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Liver Neoplasms  (ISO)
Familial Prostate Cancer  (ISO)
Fetal Growth Retardation  (ISO)
follicular lymphoma  (ISO)
Gallbladder Neoplasms  (ISO)
gastric ulcer  (ISO)
glaucoma  (ISO)
Head and Neck Neoplasms  (ISO)
Hemorrhagic Shock  (ISO)
hepatocellular carcinoma  (ISO)
Huntington's disease  (ISO)
hypertension  (ISO)
hypertrophic cardiomyopathy  (ISO)
Hypothermia  (ISO)
Hypoxia-Ischemia, Brain  (ISO)
impotence  (ISO)
intestinal disease  (ISO)
Intestinal Neoplasms  (ISO)
intracranial aneurysm  (ISO)
Kashin-Beck Disease  (ISO)
Kidney Reperfusion Injury  (ISO)
Knee Osteoarthritis  (ISO)
learning disability  (ISO)
leiomyoma  (ISO)
Liver Reperfusion Injury  (ISO)
Lung Reperfusion Injury  (ISO)
lung small cell carcinoma  (ISO)
Lymphatic Metastasis  (ISO)
male infertility  (ISO)
malignant mesothelioma  (ISO)
Mammary Neoplasms, Experimental  (ISO)
melanoma  (ISO)
Memory Disorders  (ISO)
mesenchymal chondrosarcoma  (ISO)
Metaplasia  (ISO)
middle cerebral artery infarction  (ISO)
morphine dependence  (ISO)
Multi-Infarct Dementia  (ISO)
multiple myeloma  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
nasopharynx carcinoma  (ISO)
Necrosis  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
Nerve Degeneration  (ISO)
non-Hodgkin lymphoma  (ISO)
obesity  (ISO)
Optic Nerve Injuries  (ISO)
oral mucosa leukoplakia  (ISO)
osteoarthritis  (ISO)
osteochondrodysplasia  (ISO)
osteoporosis  (ISO)
Ovarian Neoplasms  (ISO)
plasmacytoma  (ISO)
polycystic ovary syndrome  (ISO)
post-traumatic stress disorder  (ISO)
Premature Aging  (ISO)
priapism  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary hypertension  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (ISO)
Retina Reperfusion Injury  (ISO)
retinal degeneration  (ISO)
Sarcopenia  (ISO)
Soft Tissue Neoplasms  (ISO)
Spinal Cord Injuries  (ISO)
squamous cell carcinoma  (ISO)
status epilepticus  (ISO)
stomach cancer  (ISO)
Subarachnoid Hemorrhage  (ISO)
synovial sarcoma  (ISO)
T-cell acute lymphoblastic leukemia  (ISO)
Testis Reperfusion Injury  (ISO)
Tongue Neoplasms  (ISO)
transient cerebral ischemia  (ISO)
transitional cell carcinoma  (ISO)
type 2 diabetes mellitus  (ISO)
urinary bladder cancer  (ISO)
Viral Bronchiolitis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
3-keto-sphinganine metabolic process  (IBA,IEA)
actin filament organization  (ISO)
aging  (ISO)
animal organ morphogenesis  (ISO)
apoptotic mitochondrial changes  (ISO)
apoptotic process  (IEA,ISO)
axon regeneration  (ISO)
axonogenesis  (ISO)
B cell differentiation  (ISO)
B cell homeostasis  (ISO)
B cell lineage commitment  (ISO)
B cell proliferation  (ISO)
B cell receptor signaling pathway  (ISO)
behavioral fear response  (ISO)
brain development  (ISO)
branching involved in ureteric bud morphogenesis  (ISO)
CD8-positive, alpha-beta T cell lineage commitment  (ISO)
cell aging  (ISO)
cell morphogenesis  (ISO)
cell population proliferation  (ISO)
cell-cell adhesion  (ISO)
cellular calcium ion homeostasis  (ISO)
cellular response to DNA damage stimulus  (ISO)
cellular response to fluoride  (ISO)
cellular response to glucose starvation  (ISO)
cellular response to glucose stimulus  (ISO)
cellular response to hypoxia  (ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to organic substance  (ISO)
cerebral cortex development  (ISO)
cochlear nucleus development  (ISO)
defense response to virus  (ISO)
developmental growth  (ISO)
developmental pigmentation  (ISO)
digestive tract morphogenesis  (ISO)
ear development  (ISO)
endoplasmic reticulum calcium ion homeostasis  (ISO)
extrinsic apoptotic signaling pathway in absence of ligand  (ISO)
extrinsic apoptotic signaling pathway via death domain receptors  (ISO)
focal adhesion assembly  (ISO)
gland morphogenesis  (ISO)
glial cell apoptotic process  (ISO)
glomerulus development  (ISO)
hair follicle morphogenesis  (ISO)
hemopoiesis  (ISO)
homeostasis of number of cells within a tissue  (ISO)
immune system development  (ISO)
intrinsic apoptotic signaling pathway in response to DNA damage  (ISO)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress  (ISO)
intrinsic apoptotic signaling pathway in response to oxidative stress  (ISO)
kidney development  (ISO)
leukocyte homeostasis  (ISO)
liver regeneration  (ISO)
lymphocyte homeostasis  (ISO)
lymphoid progenitor cell differentiation  (ISO)
male gonad development  (ISO)
melanin metabolic process  (ISO)
melanocyte differentiation  (ISO)
mesenchymal cell development  (ISO)
metanephros development  (ISO)
negative regulation of anoikis  (ISO)
negative regulation of apoptotic process  (IEA,ISO)
negative regulation of apoptotic signaling pathway  (ISO)
negative regulation of autophagy  (ISO)
negative regulation of calcium ion transport into cytosol  (ISO)
negative regulation of cardiac muscle cell apoptotic process  (ISO)
negative regulation of cell growth  (ISO)
negative regulation of cell migration  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of cellular pH reduction  (ISO)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (ISO)
negative regulation of G1/S transition of mitotic cell cycle  (ISO)
negative regulation of intrinsic apoptotic signaling pathway  (ISO)
negative regulation of mitotic cell cycle  (ISO)
negative regulation of myeloid cell apoptotic process  (ISO)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of ossification  (ISO)
negative regulation of osteoblast proliferation  (ISO)
negative regulation of reactive oxygen species metabolic process  (ISO)
negative regulation of retinal cell programmed cell death  (ISO)
neuron apoptotic process  (ISO)
oligodendrocyte differentiation  (ISO)
oocyte development  (ISO)
organ growth  (ISO)
ossification  (ISO)
ovarian follicle development  (ISO)
peptidyl-serine phosphorylation  (ISO)
peptidyl-threonine phosphorylation  (ISO)
pigment granule organization  (ISO)
pigmentation  (ISO)
positive regulation of B cell proliferation  (ISO)
positive regulation of catalytic activity  (ISO)
positive regulation of cell growth  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of developmental pigmentation  (ISO)
positive regulation of melanocyte differentiation  (ISO)
positive regulation of multicellular organism growth  (ISO)
positive regulation of neuron maturation  (ISO)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of skeletal muscle fiber development  (ISO)
positive regulation of smooth muscle cell migration  (ISO)
post-embryonic development  (ISO)
protein dephosphorylation  (ISO)
protein polyubiquitination  (ISO)
reactive oxygen species metabolic process  (ISO)
regulation of apoptotic process  (ISO)
regulation of autophagy  (ISO)
regulation of calcium ion transport  (ISO)
regulation of catalytic activity  (ISO)
regulation of cell cycle  (ISO)
regulation of cell-matrix adhesion  (ISO)
regulation of developmental pigmentation  (ISO)
regulation of gene expression  (ISO)
regulation of glycoprotein biosynthetic process  (ISO)
regulation of growth  (ISO)
regulation of mitochondrial membrane permeability  (ISO)
regulation of mitochondrial membrane potential  (ISO)
regulation of nitrogen utilization  (ISO)
regulation of programmed cell death  (ISO)
regulation of protein localization  (ISO)
regulation of protein stability  (ISO)
regulation of transmembrane transporter activity  (ISO)
regulation of viral genome replication  (ISO)
release of cytochrome c from mitochondria  (ISO)
renal system process  (ISO)
response to aluminum ion  (ISO)
response to amyloid-beta  (ISO)
response to caffeine  (ISO)
response to cAMP  (ISO)
response to copper ion  (ISO)
response to corticosterone  (ISO)
response to cytokine  (ISO)
response to electrical stimulus  (ISO)
response to erythropoietin  (ISO)
response to estrogen  (ISO)
response to ethanol  (ISO)
response to folic acid  (ISO)
response to gamma radiation  (ISO)
response to glucocorticoid  (ISO)
response to heat  (ISO)
response to hydrogen peroxide  (ISO)
response to hypoxia  (ISO)
response to inorganic substance  (ISO)
response to insulin  (ISO)
response to iron ion  (ISO)
response to ischemia  (ISO)
response to L-ascorbic acid  (ISO)
response to monosaccharide  (ISO)
response to nicotine  (ISO)
response to nutrient  (ISO)
response to organic cyclic compound  (ISO)
response to organic substance  (ISO)
response to oxidative stress  (ISO)
response to peptide hormone  (ISO)
response to phenylpropanoid  (ISO)
response to steroid hormone  (ISO)
response to toxic substance  (ISO)
response to UV-B  (ISO)
response to vitamin E  (ISO)
response to xenobiotic stimulus  (ISO)
sphingolipid biosynthetic process  (IBA,IEA)
spleen development  (ISO)
T cell differentiation  (ISO)
T cell differentiation in thymus  (ISO)
T cell homeostasis  (ISO)
T cell lineage commitment  (ISO)
thymus development  (ISO)
ureteric bud development  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:33107129  


Genomics

Comparative Map Data
KDSR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1158,288,544 - 158,518,879 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11158,337,403 - 158,518,214 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21175,824,218 - 175,994,403 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BCL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1863,123,346 - 63,320,128 (-)EnsemblGRCh38hg38GRCh38
GRCh381863,123,346 - 63,320,280 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371860,790,579 - 60,987,002 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361858,941,559 - 59,137,593 (-)NCBINCBI36hg18NCBI36
Build 341858,941,558 - 59,136,910NCBI
Celera1857,509,356 - 57,706,116 (-)NCBI
Cytogenetic Map18q21.33NCBI
HuRef1857,487,199 - 57,684,751 (-)NCBIHuRef
CHM1_11860,786,149 - 60,982,536 (-)NCBICHM1_1
Bcl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391106,465,906 - 106,642,020 (-)NCBIGRCm39mm39
GRCm39 Ensembl1106,465,908 - 106,642,004 (-)Ensembl
GRCm381106,538,176 - 106,714,290 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1106,538,178 - 106,714,274 (-)EnsemblGRCm38mm10GRCm38
MGSCv371108,434,756 - 108,610,867 (-)NCBIGRCm37mm9NCBIm37
MGSCv361108,365,740 - 108,541,849 (-)NCBImm8
Celera1109,386,734 - 109,563,656 (-)NCBICelera
Cytogenetic Map1E2.1NCBI
cM Map149.76NCBI
Bcl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21322,689,783 - 22,853,920 (-)NCBImRatBN7.2
Rnor_6.01326,605,426 - 26,769,374 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1326,605,426 - 26,769,374 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01331,758,213 - 31,920,775 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41312,730,736 - 12,905,108 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11312,730,735 - 12,905,108 (-)NCBI
Celera1322,550,362 - 22,711,143 (-)NCBICelera
Cytogenetic Map13p11NCBI
Bcl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540246,916,266 - 47,084,485 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540246,911,125 - 47,084,214 (-)NCBIChiLan1.0ChiLan1.0
BCL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11859,797,184 - 59,993,298 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1859,802,443 - 59,992,100 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01856,481,212 - 56,679,012 (-)NCBIMhudiblu_PPA_v0panPan3
BCL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1113,733,849 - 13,900,653 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl113,731,406 - 13,900,658 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha114,699,877 - 14,866,689 (+)NCBI
ROS_Cfam_1.0113,595,394 - 13,762,294 (+)NCBI
UMICH_Zoey_3.1113,633,483 - 13,799,972 (+)NCBI
UNSW_CanFamBas_1.0113,562,764 - 13,729,319 (+)NCBI
UU_Cfam_GSD_1.0113,811,587 - 13,978,482 (+)NCBI
Bcl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494426,970,171 - 27,134,608 (+)NCBI
SpeTri2.0NW_0049364972,209,136 - 2,373,580 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11816,440,560 - 16,643,187 (+)NCBI
ChlSab1.1 Ensembl1816,441,733 - 16,637,895 (+)Ensembl
Vero_WHO_p1.0NW_0236660609,049,043 - 9,247,859 (-)NCBI
Bcl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247928,854,345 - 9,032,727 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000031522   ⟹   ENSSSCP00000019781
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1158,288,544 - 158,329,881 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000039219   ⟹   ENSSSCP00000040051
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1158,288,544 - 158,514,400 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000039416   ⟹   ENSSSCP00000045868
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1158,337,522 - 158,518,879 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000068024   ⟹   ENSSSCP00000064617
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1158,288,544 - 158,325,613 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000076201   ⟹   ENSSSCP00000067730
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1158,288,544 - 158,329,881 (+)Ensembl
RefSeq Acc Id: XM_021099593   ⟹   XP_020955252
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11158,337,403 - 158,518,214 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021099599   ⟹   XP_020955258
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11158,337,403 - 158,404,293 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021099602   ⟹   XP_020955261
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11158,337,403 - 158,424,070 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002346028
RefSeq Status:
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11158,337,403 - 158,514,337 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020955252 (Get FASTA)   NCBI Sequence Viewer  
  XP_020955258 (Get FASTA)   NCBI Sequence Viewer  
  XP_020955261 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABS57368 (Get FASTA)   NCBI Sequence Viewer  
  BAF62335 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020955252   ⟸   XM_021099593
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020955261   ⟸   XM_021099602
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_020955258   ⟸   XM_021099599
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSSSCP00000040051   ⟸   ENSSSCT00000039219
RefSeq Acc Id: ENSSSCP00000045868   ⟸   ENSSSCT00000039416
RefSeq Acc Id: ENSSSCP00000064617   ⟸   ENSSSCT00000068024
RefSeq Acc Id: ENSSSCP00000019781   ⟸   ENSSSCT00000031522
RefSeq Acc Id: ENSSSCP00000067730   ⟸   ENSSSCT00000076201
Protein Domains
BH4_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000025744 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070011763 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000040051 UniProtKB/TrEMBL
  ENSSSCP00000045868 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000064617 UniProtKB/TrEMBL
  ENSSSCP00000067730 UniProtKB/TrEMBL
  ENSSSCP00070018972 UniProtKB/TrEMBL
  ENSSSCP00070018994 UniProtKB/TrEMBL
  ENSSSCP00070018998 UniProtKB/TrEMBL
  ENSSSCP00070019011 UniProtKB/TrEMBL
  ENSSSCP00070019027 UniProtKB/TrEMBL
  ENSSSCP00070019033 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000039219 UniProtKB/TrEMBL
  ENSSSCT00000039416 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000068024 UniProtKB/TrEMBL
  ENSSSCT00000076201 UniProtKB/TrEMBL
  ENSSSCT00070022932 UniProtKB/TrEMBL
  ENSSSCT00070022958 UniProtKB/TrEMBL
  ENSSSCT00070022962 UniProtKB/TrEMBL
  ENSSSCT00070022982 UniProtKB/TrEMBL
  ENSSSCT00070023014 UniProtKB/TrEMBL
  ENSSSCT00070023021 UniProtKB/TrEMBL
Gene3D-CATH 1.10.437.10 UniProtKB/TrEMBL
InterPro Apop_reg_Bcl2 UniProtKB/TrEMBL
  Bcl2-like UniProtKB/TrEMBL
  Bcl2/BclX UniProtKB/TrEMBL
  Bcl2_BH1_motif_CS UniProtKB/TrEMBL
  Bcl2_BH2_motif_CS UniProtKB/TrEMBL
  Bcl2_BH3_motif_CS UniProtKB/TrEMBL
  Bcl2_BH4 UniProtKB/TrEMBL
  Bcl2_BH4_motif_CS UniProtKB/TrEMBL
  Blc2-like_sf UniProtKB/TrEMBL
  Blc2_fam UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
NCBI Gene BCL2 ENTREZGENE
PANTHER PTHR11256 UniProtKB/TrEMBL
  PTHR11256:SF11 UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
  Bcl-2 UniProtKB/TrEMBL
  BH4 UniProtKB/TrEMBL
PRINTS APOPREGBCL2 UniProtKB/TrEMBL
  BCL2FAMILY UniProtKB/TrEMBL
  GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/TrEMBL
  BCL2_FAMILY UniProtKB/TrEMBL
  BH1 UniProtKB/TrEMBL
  BH2 UniProtKB/TrEMBL
  BH3 UniProtKB/TrEMBL
  BH4_1 UniProtKB/TrEMBL
  BH4_2 UniProtKB/TrEMBL
SMART BCL UniProtKB/TrEMBL
  BH4 UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
  SSF56854 UniProtKB/TrEMBL
TIGRFAMs bcl-2 UniProtKB/TrEMBL
UniProt A0A287A8D8_PIG UniProtKB/TrEMBL
  A0A287APJ6_PIG UniProtKB/TrEMBL
  A0A4X1TPL5_PIG UniProtKB/TrEMBL
  A0A4X1TRR9_PIG UniProtKB/TrEMBL
  A0A4X1TRU3_PIG UniProtKB/TrEMBL
  A0A4X1TUJ9_PIG UniProtKB/TrEMBL
  A0A4X1TUK1_PIG UniProtKB/TrEMBL
  A0A4X1TUL2_PIG UniProtKB/TrEMBL
  A0A5G2QJG8_PIG UniProtKB/TrEMBL
  A0A5G2QS28_PIG UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-08-02 KDSR  3-ketodihydrosphingosine reductase  BCL2  BCL2 apoptosis regulator  Symbol and/or name change 19259463 PROVISIONAL