GPAM (glycerol-3-phosphate acyltransferase, mitochondrial) - Rat Genome Database

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Gene: GPAM (glycerol-3-phosphate acyltransferase, mitochondrial) Sus scrofa
Analyze
Symbol: GPAM
Name: glycerol-3-phosphate acyltransferase, mitochondrial
RGD ID: 13955580
Description: ENCODES a protein that exhibits glycerol-3-phosphate O-acyltransferase activity (ortholog); INVOLVED IN activated T cell proliferation (ortholog); activation-induced cell death of T cells (ortholog); acyl-CoA metabolic process (ortholog); PARTICIPATES IN D-glycericacidemia pathway; familial lipoprotein lipase deficiency pathway; glycerol kinase deficiency pathway; ASSOCIATED WITH Experimental Diabetes Mellitus (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN mitochondrial membrane (ortholog); mitochondrial outer membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Glycerol-3-phosphate acyltransferase 1, mitochondrial; GPAT; GPAT-1; GPAT1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14122,538,603 - 122,579,148 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114122,538,600 - 122,582,390 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214133,473,315 - 133,545,241 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14510680   PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202   PMID:31918054  


Genomics

Comparative Map Data
GPAM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14122,538,603 - 122,579,148 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114122,538,600 - 122,582,390 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214133,473,315 - 133,545,241 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GPAM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810112,149,865 - 112,227,677 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10112,149,865 - 112,215,377 (-)EnsemblGRCh38hg38GRCh38
GRCh3710113,909,623 - 113,943,523 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610113,899,612 - 113,933,508 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410113,899,611 - 113,933,508NCBI
Celera10107,637,183 - 107,671,081 (-)NCBICelera
Cytogenetic Map10q25.2NCBI
HuRef10107,537,900 - 107,571,823 (-)NCBIHuRef
CHM1_110114,191,437 - 114,225,332 (-)NCBICHM1_1
T2T-CHM13v2.010113,040,886 - 113,118,691 (-)NCBIT2T-CHM13v2.0
Gpam
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391955,056,067 - 55,115,666 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1955,055,700 - 55,115,670 (-)EnsemblGRCm39 Ensembl
GRCm381955,067,635 - 55,127,319 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1955,067,268 - 55,127,238 (-)EnsemblGRCm38mm10GRCm38
MGSCv371955,144,224 - 55,173,937 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361955,122,984 - 55,152,703 (-)NCBIMGSCv36mm8
Celera1957,260,690 - 57,290,402 (-)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1950.81NCBI
Gpam
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81264,111,599 - 264,176,112 (-)NCBIGRCr8
mRatBN7.21254,106,323 - 254,170,755 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1254,106,331 - 254,142,639 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1262,315,818 - 262,376,481 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01269,021,904 - 269,082,569 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01261,664,129 - 261,730,618 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01275,843,823 - 275,906,880 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1275,846,819 - 275,906,686 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01283,246,186 - 283,309,245 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41261,370,264 - 261,431,434 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11261,581,308 - 261,642,479 (-)NCBI
Celera1249,818,009 - 249,877,839 (-)NCBICelera
Cytogenetic Map1q55NCBI
Gpam
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543117,291,270 - 17,363,714 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543117,291,890 - 17,363,611 (-)NCBIChiLan1.0ChiLan1.0
GPAM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28124,031,551 - 124,065,468 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110124,036,887 - 124,070,804 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010108,747,370 - 108,781,270 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110112,186,744 - 112,246,549 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10112,186,744 - 112,246,549 (-)Ensemblpanpan1.1panPan2
GPAM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12823,261,673 - 23,323,985 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2823,258,428 - 23,298,017 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2823,413,452 - 23,450,047 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02823,793,834 - 23,830,470 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2823,793,834 - 23,830,650 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12823,351,250 - 23,387,551 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02823,362,221 - 23,398,810 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02823,557,678 - 23,594,318 (-)NCBIUU_Cfam_GSD_1.0
Gpam
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721322,737,594 - 22,806,520 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364862,754,751 - 2,823,665 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364862,754,753 - 2,823,600 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPAM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19105,049,954 - 105,083,750 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9105,049,711 - 105,113,374 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604866,253,108 - 66,316,689 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpam
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473734,198,518 - 34,265,192 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473734,198,773 - 34,268,815 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GPAM
1260 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 19 1
Low 10 4 3 5 1 4 2 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000011627   ⟹   ENSSSCP00000011325
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl14122,538,603 - 122,579,148 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000071318   ⟹   ENSSSCP00000065565
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl14122,538,603 - 122,579,148 (-)Ensembl
RefSeq Acc Id: XM_005671462   ⟹   XP_005671519
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.114122,538,600 - 122,582,390 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005671519 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAP74372 (Get FASTA)   NCBI Sequence Viewer  
  AAP74373 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000011325
  ENSSSCP00000011325.3
  ENSSSCP00000065565.2
  ENSSSCP00045016515.1
  ENSSSCP00050018517.1
GenBank Protein F1S5L4 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005671519   ⟸   XM_005671462
- UniProtKB: Q7YS07 (UniProtKB/Swiss-Prot),   F1S5L4 (UniProtKB/Swiss-Prot),   A0A0N4SWI8 (UniProtKB/TrEMBL),   A0A480SGQ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000011325   ⟸   ENSSSCT00000011627
RefSeq Acc Id: ENSSSCP00000065565   ⟸   ENSSSCT00000071318
Protein Domains
Phospholipid/glycerol acyltransferase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010631 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00045014059 UniProtKB/Swiss-Prot
  ENSSSCG00050033629 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000011627 ENTREZGENE
  ENSSSCT00000011627.5 UniProtKB/TrEMBL
  ENSSSCT00000071318.2 UniProtKB/TrEMBL
  ENSSSCT00045023945.1 UniProtKB/Swiss-Prot
  ENSSSCT00050045061.1 UniProtKB/Swiss-Prot
InterPro GPAT/DHAPAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPAT/DHAPAT_LPLAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPAT_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPAT_PlsB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Plipid/glycerol_acylTrfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397629 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene GPAM ENTREZGENE
PANTHER GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12563 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Acyltransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPAT_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF GPAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPAT_DHAPAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PlsC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glycerol-3-phosphate (1)-acyltransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0N4SWI8 ENTREZGENE, UniProtKB/TrEMBL
  A0A480SGQ5 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QL68_PIG UniProtKB/TrEMBL
  F1S5L4 ENTREZGENE, UniProtKB/Swiss-Prot
  Q7YS07 ENTREZGENE
UniProt Secondary Q7YS07 UniProtKB/Swiss-Prot
VGNC ID VGNC:88570 ENTREZGENE