POGZ (pogo transposable element derived with ZNF domain) - Rat Genome Database

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Gene: POGZ (pogo transposable element derived with ZNF domain) Sus scrofa
Analyze
Symbol: POGZ
Name: pogo transposable element derived with ZNF domain
RGD ID: 14181629
Description: ENCODES a protein that exhibits nucleic acid binding (inferred); zinc ion binding (inferred); INVOLVED IN double-strand break repair via homologous recombination (inferred); kinetochore assembly (inferred); mitotic sister chromatid cohesion (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); Dravet syndrome (ortholog); FOUND IN chromatin (inferred); ciliary basal body (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pogo transposable element with ZNF domain
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl497,776,589 - 97,833,282 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1497,776,579 - 97,833,287 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24106,997,208 - 107,034,066 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 16 of 16 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
POGZPigautism spectrum disorder  ISOPOGZ (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
POGZPigDevelopmental Disabilities  ISOPOGZ (Homo sapiens)8554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:25741868 more ...
POGZPigDravet syndrome  ISOPOGZ (Homo sapiens)8554872ClinVar Annotator: match by term: Severe myoclonic epilepsy in infancyClinVarPMID:25894286 and PMID:28492532
POGZPigDwarfism  ISOPOGZ (Homo sapiens)8554872ClinVar Annotator: match by term: Short statureClinVar 
POGZPiggastrointestinal stromal tumor  ISOPOGZ (Homo sapiens)8554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:28492532
POGZPiggenetic disease  ISOPOGZ (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:20562864 more ...
POGZPigHypertelorism  ISOPOGZ (Homo sapiens)8554872ClinVar Annotator: match by term: HypertelorismClinVarPMID:25741868
POGZPigimmunodeficiency 42  ISOPOGZ (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal recessive mendelian susceptibility to mycobacterial diseases due to complete RORgamma receptor deficiencyClinVarPMID:28492532
POGZPigintellectual disability  ISOPOGZ (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
POGZPigMHC class II deficiency  ISOPOGZ (Homo sapiens)8554872ClinVar Annotator: match by term: MHC class II deficiencyClinVarPMID:28492532
POGZPigNeurodevelopmental Disorders  ISOPOGZ (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868 more ...
POGZPigobesity  ISOPOGZ (Homo sapiens)8554872ClinVar Annotator: match by term: ObesityClinVar 
POGZPigparathyroid carcinoma  ISOPOGZ (Homo sapiens)8554872ClinVar Annotator: match by term: Parathyroid carcinomaClinVarPMID:28492532
POGZPigsevere congenital neutropenia 3  ISOPOGZ (Homo sapiens)8554872ClinVar Annotator: match by term: Kostmann syndromeClinVarPMID:28492532
POGZPigsevere congenital neutropenia 5  ISOPOGZ (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital neutropenia-myelofibrosis-nephromegaly syndromeClinVarPMID:28492532
POGZPigWhite-Sutton syndrome  ISOPOGZ (Homo sapiens)8554872ClinVar more ...ClinVarPMID:22495311 more ...
1 to 16 of 16 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
POGZPigWhite-Sutton syndrome  ISOPOGZ (Homo sapiens)7240710 OMIM 


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
POGZPigdouble-strand break repair via homologous recombination acts_upstream_of_or_within_positive_effectIEAUniProtKB:Q7Z3K3 and ensembl:ENSP00000271715150520179 EnsemblGO_REF:0000107
POGZPigkinetochore assembly involved_inIEAUniProtKB:Q7Z3K3 and ensembl:ENSP00000271715150520179 EnsemblGO_REF:0000107
POGZPigmitotic sister chromatid cohesion involved_inIEAUniProtKB:Q7Z3K3 and ensembl:ENSP00000271715150520179 EnsemblGO_REF:0000107
POGZPigpositive regulation of transcription by RNA polymerase II involved_inIBAFB:FBgn0033185 more ...150520179 GO_CentralGO_REF:0000033

Cellular Component
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
POGZPigchromatin located_inIEAUniProtKB:Q7Z3K3 and ensembl:ENSP00000271715150520179 EnsemblGO_REF:0000107
POGZPigciliary basal body located_inIEAUniProtKB:Q7Z3K3 and ensembl:ENSP00000271715150520179 EnsemblGO_REF:0000107
POGZPigcytoplasm located_inIEAUniProtKB:Q7Z3K3 and ensembl:ENSP00000271715150520179 EnsemblGO_REF:0000107
POGZPigcytosol located_inIEAUniProtKB:Q7Z3K3 and ensembl:ENSP00000271715150520179 EnsemblGO_REF:0000107
POGZPignucleoplasm located_inIEAUniProtKB:Q7Z3K3 and ensembl:ENSP00000271715150520179 EnsemblGO_REF:0000107
POGZPignucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
POGZPignucleus is_active_inIBAFB:FBgn0032473 more ...150520179 GO_CentralGO_REF:0000033
POGZPignucleus located_inIEAUniProtKB:Q7Z3K3 and ensembl:ENSP00000271715150520179 EnsemblGO_REF:0000107
POGZPigplasma membrane located_inIEAUniProtKB:Q7Z3K3 and ensembl:ENSP00000271715150520179 EnsemblGO_REF:0000107
1 to 9 of 9 rows

Molecular Function
1 to 13 of 13 rows

  
1 to 13 of 13 rows

PMID:30032202  



POGZ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl497,776,589 - 97,833,282 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1497,776,579 - 97,833,287 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24106,997,208 - 107,034,066 (+)NCBISscrofa10.2Sscrofa10.2susScr3
POGZ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381151,402,724 - 151,459,494 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1151,402,724 - 151,459,494 (-)EnsemblGRCh38hg38GRCh38
GRCh371151,375,200 - 151,431,970 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361149,641,824 - 149,698,556 (-)NCBINCBI36Build 36hg18NCBI36
Build 341148,188,272 - 148,245,005NCBI
Celera1124,490,466 - 124,547,192 (-)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1122,753,210 - 122,809,847 (-)NCBIHuRef
CHM1_11152,770,790 - 152,827,420 (-)NCBICHM1_1
T2T-CHM13v2.01150,526,433 - 150,583,190 (-)NCBIT2T-CHM13v2.0
Pogz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39394,730,289 - 94,790,888 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl394,744,878 - 94,789,637 (+)EnsemblGRCm39 Ensembl
GRCm38394,822,989 - 94,883,577 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl394,837,567 - 94,882,326 (+)EnsemblGRCm38mm10GRCm38
MGSCv37394,641,489 - 94,687,491 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36394,923,117 - 94,966,213 (+)NCBIMGSCv36mm8
Celera396,268,238 - 96,314,269 (+)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map340.74NCBI
Pogz
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82185,069,492 - 185,129,741 (+)NCBIGRCr8
mRatBN7.22182,394,269 - 182,440,711 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2182,380,768 - 182,440,707 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2190,077,496 - 190,105,366 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02187,872,867 - 187,900,748 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02182,709,966 - 182,737,835 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02195,995,322 - 196,041,500 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2195,996,521 - 196,041,497 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02215,507,126 - 215,534,827 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42189,748,657 - 189,776,355 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12189,685,298 - 189,728,992 (+)NCBI
Celera2174,957,108 - 174,984,012 (+)NCBICelera
Cytogenetic Map2q34NCBI
Pogz
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955589920,508 - 976,366 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955589920,729 - 975,242 (+)NCBIChiLan1.0ChiLan1.0
POGZ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2198,351,060 - 98,420,975 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1198,102,244 - 98,172,148 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01126,761,777 - 126,818,262 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11130,407,426 - 130,463,909 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1130,407,426 - 130,463,909 (-)Ensemblpanpan1.1panPan2
POGZ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11760,464,609 - 60,511,735 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1760,465,230 - 60,511,934 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1759,909,098 - 59,954,694 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01761,482,101 - 61,528,240 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1761,480,642 - 61,528,466 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11760,309,922 - 60,355,542 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01760,395,876 - 60,441,670 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01761,124,503 - 61,170,655 (-)NCBIUU_Cfam_GSD_1.0
Pogz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505822,583,808 - 22,620,357 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365801,615,713 - 1,650,874 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365801,613,425 - 1,650,849 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POGZ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12012,236,036 - 12,290,937 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2012,236,145 - 12,290,956 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603811,809,947 - 11,865,321 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pogz
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477219,127,702 - 19,184,048 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477219,127,702 - 19,184,151 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in POGZ
1416 total Variants



alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3



Ensembl Acc Id: ENSSSCT00000007256   ⟹   ENSSSCP00000007061
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl497,776,589 - 97,833,282 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000046893   ⟹   ENSSSCP00000036265
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl497,776,640 - 97,831,512 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000048783   ⟹   ENSSSCP00000045549
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl497,776,589 - 97,833,282 (+)Ensembl
RefSeq Acc Id: XM_005663450   ⟹   XP_005663507
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1497,776,587 - 97,833,287 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005663451   ⟹   XP_005663508
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1497,776,579 - 97,833,287 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021089861   ⟹   XP_020945520
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1497,776,618 - 97,833,287 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021089862   ⟹   XP_020945521
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1497,776,618 - 97,833,287 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005663508   ⟸   XM_005663451
- Peptide Label: isoform X2
- UniProtKB: A0A4X1W0X7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005663507   ⟸   XM_005663450
- Peptide Label: isoform X1
- UniProtKB: A0A287AYD9 (UniProtKB/TrEMBL),   A0A8D1Z8Q8 (UniProtKB/TrEMBL),   F1ST03 (UniProtKB/TrEMBL),   A0A4X1VVP8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020945520   ⟸   XM_021089861
- Peptide Label: isoform X3
- UniProtKB: A0A286ZXB6 (UniProtKB/TrEMBL),   A0A8D2CAQ3 (UniProtKB/TrEMBL),   A0A8D0TU57 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020945521   ⟸   XM_021089862
- Peptide Label: isoform X4
- UniProtKB: A0A8D0MDU1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000045549   ⟸   ENSSSCT00000048783
C2H2-type   HTH CENPB-type



1 to 40 of 103 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSSSCG00000006622 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015004002 UniProtKB/TrEMBL
  ENSSSCG00025056041 UniProtKB/TrEMBL
  ENSSSCG00030064772 UniProtKB/TrEMBL
  ENSSSCG00035068417 UniProtKB/TrEMBL
  ENSSSCG00040073972 UniProtKB/TrEMBL
  ENSSSCG00045006475 UniProtKB/TrEMBL
  ENSSSCG00050039822 UniProtKB/TrEMBL
  ENSSSCG00055020143 UniProtKB/TrEMBL
  ENSSSCG00060075281 UniProtKB/TrEMBL
  ENSSSCG00065052498 UniProtKB/TrEMBL
  ENSSSCG00070028053 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000007256 ENTREZGENE
  ENSSSCT00000007256.5 UniProtKB/TrEMBL
  ENSSSCT00000046893 ENTREZGENE
  ENSSSCT00000046893.3 UniProtKB/TrEMBL
  ENSSSCT00000048783 ENTREZGENE
  ENSSSCT00000048783.3 UniProtKB/TrEMBL
  ENSSSCT00015005298.1 UniProtKB/TrEMBL
  ENSSSCT00015005313.1 UniProtKB/TrEMBL
  ENSSSCT00015005321.1 UniProtKB/TrEMBL
  ENSSSCT00015005351.1 UniProtKB/TrEMBL
  ENSSSCT00015005370.1 UniProtKB/TrEMBL
  ENSSSCT00015005383.1 UniProtKB/TrEMBL
  ENSSSCT00015005401.1 UniProtKB/TrEMBL
  ENSSSCT00025077221.1 UniProtKB/TrEMBL
  ENSSSCT00025077838.1 UniProtKB/TrEMBL
  ENSSSCT00025078140.1 UniProtKB/TrEMBL
  ENSSSCT00030091570.1 UniProtKB/TrEMBL
  ENSSSCT00030091609.1 UniProtKB/TrEMBL
  ENSSSCT00030091624.1 UniProtKB/TrEMBL
  ENSSSCT00030091654.1 UniProtKB/TrEMBL
  ENSSSCT00035092444.1 UniProtKB/TrEMBL
  ENSSSCT00035092514.1 UniProtKB/TrEMBL
  ENSSSCT00035092534.1 UniProtKB/TrEMBL
  ENSSSCT00035092613.1 UniProtKB/TrEMBL
  ENSSSCT00040102241.1 UniProtKB/TrEMBL
  ENSSSCT00040102284.1 UniProtKB/TrEMBL
  ENSSSCT00040102401.1 UniProtKB/TrEMBL
  ENSSSCT00045010797.1 UniProtKB/TrEMBL
1 to 40 of 103 rows