HDAC8 (histone deacetylase 8) - Rat Genome Database

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Gene: HDAC8 (histone deacetylase 8) Sus scrofa
Analyze
Symbol: HDAC8
Name: histone deacetylase 8
RGD ID: 13872743
Description: ENCODES a protein that exhibits chromatin binding (ortholog); deacetylase activity (ortholog); transcription factor binding (ortholog); INVOLVED IN cellular response to forskolin (ortholog); cellular response to trichostatin A (ortholog); negative regulation of gene expression (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH amphetamine abuse (ortholog); atrial heart septal defect (ortholog); autistic disorder (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X58,210,182 - 58,450,681 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
HDAC8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X58,210,182 - 58,450,681 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
HDAC8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X72,329,516 - 72,572,843 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX72,329,516 - 72,573,101 (-)EnsemblGRCh38hg38GRCh38
GRCh37X71,549,366 - 71,792,693 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X71,466,091 - 71,709,378 (-)NCBINCBI36hg18NCBI36
Build 34X71,332,387 - 71,575,674NCBI
CeleraX71,892,584 - 72,136,175 (-)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX65,303,729 - 65,547,461 (-)NCBIHuRef
CHM1_1X71,442,370 - 71,685,931 (-)NCBICHM1_1
T2T-CHM13v2.0X70,762,405 - 71,005,758 (-)NCBI
Hdac8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X101,328,244 - 101,549,005 (-)NCBIGRCm39mm39
GRCm39 EnsemblX101,328,245 - 101,548,965 (-)Ensembl
GRCm38X102,284,638 - 102,505,381 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX102,284,639 - 102,505,359 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X99,479,979 - 99,700,487 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X98,487,359 - 98,707,867 (-)NCBImm8
CeleraX89,195,856 - 89,416,063 (-)NCBICelera
Cytogenetic MapXDNCBI
Hdac8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X67,385,288 - 67,593,014 (-)NCBImRatBN7.2
mRatBN7.2 EnsemblX67,385,289 - 67,592,923 (-)Ensembl
Rnor_6.0X72,163,777 - 72,370,058 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX72,163,777 - 72,370,044 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X73,566,613 - 73,589,000 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0X73,694,610 - 73,698,948 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X90,336,001 - 90,544,511 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX67,738,891 - 67,946,303 (-)NCBICelera
Cytogenetic MapXq22NCBI
Hdac8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495547511,748,502 - 12,012,884 (-)NCBIChiLan1.0ChiLan1.0
HDAC8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X71,649,178 - 71,894,896 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0X61,565,790 - 61,811,588 (-)NCBIMhudiblu_PPA_v0panPan3
HDAC8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X56,357,205 - 56,574,443 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX56,357,177 - 56,574,401 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX47,183,095 - 47,400,619 (-)NCBI
ROS_Cfam_1.0X57,411,265 - 57,628,877 (-)NCBI
ROS_Cfam_1.0 EnsemblX57,411,268 - 57,628,840 (-)Ensembl
UMICH_Zoey_3.1X55,325,722 - 55,544,604 (-)NCBI
UNSW_CanFamBas_1.0X56,723,145 - 56,940,470 (-)NCBI
UU_Cfam_GSD_1.0X56,571,889 - 56,789,465 (-)NCBI
Hdac8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X45,327,793 - 45,554,498 (+)NCBI
SpeTri2.0NW_0049367621,425,337 - 1,652,058 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HDAC8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X62,154,374 - 62,393,149 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 EnsemblX62,154,365 - 62,393,196 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660654,003,868 - 4,261,439 (-)NCBIVero_WHO_p1.0
Hdac8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249032,620,501 - 2,852,822 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046249032,620,571 - 2,852,247 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1 1
Low 10 3 3 4 2 23 2 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: XM_021080458   ⟹   XP_020936117
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X58,244,080 - 58,450,681 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021080459   ⟹   XP_020936118
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X58,210,182 - 58,450,610 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002340774
RefSeq Status:
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X58,354,211 - 58,450,544 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020936117 (Get FASTA)   NCBI Sequence Viewer  
  XP_020936118 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020936118   ⟸   XM_021080459
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020936117   ⟸   XM_021080458
- Peptide Label: isoform X1
- Sequence:
Protein Domains
Hist_deacetyl


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000021200 UniProtKB/TrEMBL
  ENSSSCG00005015895 UniProtKB/TrEMBL
  ENSSSCG00015040936 UniProtKB/TrEMBL
  ENSSSCG00025069755 UniProtKB/TrEMBL
  ENSSSCG00030050735 UniProtKB/TrEMBL
  ENSSSCG00035040860 UniProtKB/TrEMBL
  ENSSSCG00040011344 UniProtKB/TrEMBL
  ENSSSCG00045026643 UniProtKB/TrEMBL
  ENSSSCG00050011961 UniProtKB/TrEMBL
  ENSSSCG00055006594 UniProtKB/TrEMBL
  ENSSSCG00060006062 UniProtKB/TrEMBL
  ENSSSCG00065009850 UniProtKB/TrEMBL
  ENSSSCG00070000401 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000013206 UniProtKB/TrEMBL
  ENSSSCP00000019421 UniProtKB/TrEMBL
  ENSSSCP00000024739 UniProtKB/TrEMBL
  ENSSSCP00000042820 UniProtKB/TrEMBL
  ENSSSCP00000056206 UniProtKB/TrEMBL
  ENSSSCP00000061689 UniProtKB/TrEMBL
  ENSSSCP00000063658 UniProtKB/TrEMBL
  ENSSSCP00000066640 UniProtKB/TrEMBL
  ENSSSCP00000074529 UniProtKB/TrEMBL
  ENSSSCP00005015231 UniProtKB/TrEMBL
  ENSSSCP00005015573 UniProtKB/TrEMBL
  ENSSSCP00005015599 UniProtKB/TrEMBL
  ENSSSCP00005015699 UniProtKB/TrEMBL
  ENSSSCP00005015714 UniProtKB/TrEMBL
  ENSSSCP00005015734 UniProtKB/TrEMBL
  ENSSSCP00005015772 UniProtKB/TrEMBL
  ENSSSCP00005015785 UniProtKB/TrEMBL
  ENSSSCP00005015837 UniProtKB/TrEMBL
  ENSSSCP00015022165 UniProtKB/TrEMBL
  ENSSSCP00015022410 UniProtKB/TrEMBL
  ENSSSCP00015022447 UniProtKB/TrEMBL
  ENSSSCP00025042202 UniProtKB/TrEMBL
  ENSSSCP00025042463 UniProtKB/TrEMBL
  ENSSSCP00025042749 UniProtKB/TrEMBL
  ENSSSCP00025042846 UniProtKB/TrEMBL
  ENSSSCP00025042898 UniProtKB/TrEMBL
  ENSSSCP00030032444 UniProtKB/TrEMBL
  ENSSSCP00030032483 UniProtKB/TrEMBL
  ENSSSCP00030032524 UniProtKB/TrEMBL
  ENSSSCP00030032539 UniProtKB/TrEMBL
  ENSSSCP00030032598 UniProtKB/TrEMBL
  ENSSSCP00030032605 UniProtKB/TrEMBL
  ENSSSCP00035021844 UniProtKB/TrEMBL
  ENSSSCP00035021847 UniProtKB/TrEMBL
  ENSSSCP00035021848 UniProtKB/TrEMBL
  ENSSSCP00035021856 UniProtKB/TrEMBL
  ENSSSCP00035021858 UniProtKB/TrEMBL
  ENSSSCP00035021859 UniProtKB/TrEMBL
  ENSSSCP00035021860 UniProtKB/TrEMBL
  ENSSSCP00035021862 UniProtKB/TrEMBL
  ENSSSCP00035021871 UniProtKB/TrEMBL
  ENSSSCP00035021873 UniProtKB/TrEMBL
  ENSSSCP00040005799 UniProtKB/TrEMBL
  ENSSSCP00040005806 UniProtKB/TrEMBL
  ENSSSCP00045031635 UniProtKB/TrEMBL
  ENSSSCP00045031757 UniProtKB/TrEMBL
  ENSSSCP00045031927 UniProtKB/TrEMBL
  ENSSSCP00050006622 UniProtKB/TrEMBL
  ENSSSCP00050006641 UniProtKB/TrEMBL
  ENSSSCP00055010044 UniProtKB/TrEMBL
  ENSSSCP00055010096 UniProtKB/TrEMBL
  ENSSSCP00055010129 UniProtKB/TrEMBL
  ENSSSCP00055010181 UniProtKB/TrEMBL
  ENSSSCP00055010209 UniProtKB/TrEMBL
  ENSSSCP00055010229 UniProtKB/TrEMBL
  ENSSSCP00055010250 UniProtKB/TrEMBL
  ENSSSCP00055010274 UniProtKB/TrEMBL
  ENSSSCP00055010406 UniProtKB/TrEMBL
  ENSSSCP00055010451 UniProtKB/TrEMBL
  ENSSSCP00060002785 UniProtKB/TrEMBL
  ENSSSCP00060002801 UniProtKB/TrEMBL
  ENSSSCP00060002802 UniProtKB/TrEMBL
  ENSSSCP00065005341 UniProtKB/TrEMBL
  ENSSSCP00065005352 UniProtKB/TrEMBL
  ENSSSCP00065005353 UniProtKB/TrEMBL
  ENSSSCP00065005362 UniProtKB/TrEMBL
  ENSSSCP00070000729 UniProtKB/TrEMBL
  ENSSSCP00070000741 UniProtKB/TrEMBL
  ENSSSCP00070000745 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000013570 UniProtKB/TrEMBL
  ENSSSCT00000025734 UniProtKB/TrEMBL
  ENSSSCT00000027685 UniProtKB/TrEMBL
  ENSSSCT00000047819 UniProtKB/TrEMBL
  ENSSSCT00000063668 UniProtKB/TrEMBL
  ENSSSCT00000069276 UniProtKB/TrEMBL
  ENSSSCT00000072563 UniProtKB/TrEMBL
  ENSSSCT00000078850 UniProtKB/TrEMBL
  ENSSSCT00000082122 UniProtKB/TrEMBL
  ENSSSCT00005025203 UniProtKB/TrEMBL
  ENSSSCT00005025708 UniProtKB/TrEMBL
  ENSSSCT00005025757 UniProtKB/TrEMBL
  ENSSSCT00005025916 UniProtKB/TrEMBL
  ENSSSCT00005025939 UniProtKB/TrEMBL
  ENSSSCT00005025974 UniProtKB/TrEMBL
  ENSSSCT00005026035 UniProtKB/TrEMBL
  ENSSSCT00005026055 UniProtKB/TrEMBL
  ENSSSCT00005026132 UniProtKB/TrEMBL
  ENSSSCT00015055240 UniProtKB/TrEMBL
  ENSSSCT00015055749 UniProtKB/TrEMBL
  ENSSSCT00015055860 UniProtKB/TrEMBL
  ENSSSCT00025096111 UniProtKB/TrEMBL
  ENSSSCT00025096734 UniProtKB/TrEMBL
  ENSSSCT00025097350 UniProtKB/TrEMBL
  ENSSSCT00025097565 UniProtKB/TrEMBL
  ENSSSCT00025097670 UniProtKB/TrEMBL
  ENSSSCT00030071153 UniProtKB/TrEMBL
  ENSSSCT00030071226 UniProtKB/TrEMBL
  ENSSSCT00030071328 UniProtKB/TrEMBL
  ENSSSCT00030071362 UniProtKB/TrEMBL
  ENSSSCT00030071496 UniProtKB/TrEMBL
  ENSSSCT00030071517 UniProtKB/TrEMBL
  ENSSSCT00035054310 UniProtKB/TrEMBL
  ENSSSCT00035054317 UniProtKB/TrEMBL
  ENSSSCT00035054318 UniProtKB/TrEMBL
  ENSSSCT00035054334 UniProtKB/TrEMBL
  ENSSSCT00035054339 UniProtKB/TrEMBL
  ENSSSCT00035054342 UniProtKB/TrEMBL
  ENSSSCT00035054345 UniProtKB/TrEMBL
  ENSSSCT00035054348 UniProtKB/TrEMBL
  ENSSSCT00035054368 UniProtKB/TrEMBL
  ENSSSCT00035054375 UniProtKB/TrEMBL
  ENSSSCT00040014859 UniProtKB/TrEMBL
  ENSSSCT00040014869 UniProtKB/TrEMBL
  ENSSSCT00045045591 UniProtKB/TrEMBL
  ENSSSCT00045045761 UniProtKB/TrEMBL
  ENSSSCT00045045988 UniProtKB/TrEMBL
  ENSSSCT00050016158 UniProtKB/TrEMBL
  ENSSSCT00050016186 UniProtKB/TrEMBL
  ENSSSCT00055012767 UniProtKB/TrEMBL
  ENSSSCT00055012837 UniProtKB/TrEMBL
  ENSSSCT00055012880 UniProtKB/TrEMBL
  ENSSSCT00055012946 UniProtKB/TrEMBL
  ENSSSCT00055012992 UniProtKB/TrEMBL
  ENSSSCT00055013020 UniProtKB/TrEMBL
  ENSSSCT00055013049 UniProtKB/TrEMBL
  ENSSSCT00055013082 UniProtKB/TrEMBL
  ENSSSCT00055013243 UniProtKB/TrEMBL
  ENSSSCT00055013293 UniProtKB/TrEMBL
  ENSSSCT00060007746 UniProtKB/TrEMBL
  ENSSSCT00060007767 UniProtKB/TrEMBL
  ENSSSCT00060007769 UniProtKB/TrEMBL
  ENSSSCT00065013100 UniProtKB/TrEMBL
  ENSSSCT00065013122 UniProtKB/TrEMBL
  ENSSSCT00065013126 UniProtKB/TrEMBL
  ENSSSCT00065013143 UniProtKB/TrEMBL
  ENSSSCT00070000829 UniProtKB/TrEMBL
  ENSSSCT00070000842 UniProtKB/TrEMBL
  ENSSSCT00070000847 UniProtKB/TrEMBL
Gene3D-CATH 3.40.800.20 UniProtKB/TrEMBL
InterPro His_deacetylse UniProtKB/TrEMBL
  His_deacetylse_1 UniProtKB/TrEMBL
  His_deacetylse_dom UniProtKB/TrEMBL
  His_deacetylse_dom_sf UniProtKB/TrEMBL
  Ureohydrolase_dom_sf UniProtKB/TrEMBL
NCBI Gene HDAC8 ENTREZGENE
Pfam Hist_deacetyl UniProtKB/TrEMBL
PIRSF His_deacetylse_1 UniProtKB/TrEMBL
PRINTS HDASUPER UniProtKB/TrEMBL
  HISDACETLASE UniProtKB/TrEMBL
Superfamily-SCOP SSF52768 UniProtKB/TrEMBL
UniProt A0A287AFM4_PIG UniProtKB/TrEMBL
  A0A287BJF9_PIG UniProtKB/TrEMBL
  A0A480MIE7_PIG UniProtKB/TrEMBL
  A0A4X1SEV5_PIG UniProtKB/TrEMBL
  A0A4X1SEX0_PIG UniProtKB/TrEMBL
  A0A4X1SEY3_PIG UniProtKB/TrEMBL
  A0A5G2QC79_PIG UniProtKB/TrEMBL
  A0A5G2QPL1_PIG UniProtKB/TrEMBL
  A0A5G2RHA1_PIG UniProtKB/TrEMBL
  A0A8D0IYD7_PIG UniProtKB/TrEMBL
  A0A8D0IYS6_PIG UniProtKB/TrEMBL
  A0A8D0NRM5_PIG UniProtKB/TrEMBL
  A0A8D0T809_PIG UniProtKB/TrEMBL
  A0A8D0X8L4_PIG UniProtKB/TrEMBL
  A0A8D0ZPY4_PIG UniProtKB/TrEMBL
  A0A8D0ZU01_PIG UniProtKB/TrEMBL
  A0A8D0ZZH9_PIG UniProtKB/TrEMBL
  A0A8D0ZZI9_PIG UniProtKB/TrEMBL
  A0A8D1PYW3_PIG UniProtKB/TrEMBL
  A0A8D1Q091_PIG UniProtKB/TrEMBL
  A0A8D1TWV2_PIG UniProtKB/TrEMBL
  A0A8D1XFL5_PIG UniProtKB/TrEMBL
  F1RPM1_PIG UniProtKB/TrEMBL
  I3L5X0_PIG UniProtKB/TrEMBL
  I3LKX4_PIG UniProtKB/TrEMBL