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Gene: CD40LG (CD40 ligand) Sus scrofa

Analyze

Symbol:

CD40LG

Name:

CD40 ligand

RGD ID:

14051906

Description:

ENCODES a protein that exhibits CD40 receptor binding (ortholog); protein serine/threonine kinase activator activity (ortholog); INVOLVED IN B cell proliferation (ortholog); CD40 signaling pathway (ortholog); cellular response to tumor necrosis factor (ortholog); PARTICIPATES IN interleukin-4 signaling pathway; obesity pathway; ASSOCIATED WITH acquired immunodeficiency syndrome (ortholog); Acute Coronary Syndrome (ortholog); acute lymphoblastic leukemia (ortholog); FOUND IN cell body (ortholog); cell projection (ortholog); cell surface (ortholog); INTERACTS WITH 17beta-estradiol

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome); CD40-L; CD40L; TNFSF5; tumor necrosis factor (ligand) superfamily, member 5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CD40LG (CD40 ligand)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Cd40lg (CD40 ligand)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Cd40lg (CD40 ligand)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cd40lg (CD40 ligand)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CD40LG (CD40 ligand)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CD40LG (CD40 ligand)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cd40lg (CD40 ligand)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CD40LG (CD40 ligand)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cd40lg (CD40 ligand)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	111,778,493 - 111,789,709 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	111,778,666 - 111,788,901 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	127,636,797 - 127,647,035 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acquired immunodeficiency syndrome (ISO)

Acute Coronary Syndrome (ISO)

acute lymphoblastic leukemia (ISO)

allergic disease (ISO)

allergic rhinitis (ISO)

Alzheimer's disease (ISO)

amyotrophic lateral sclerosis (ISO)

anti-basement membrane glomerulonephritis (ISO)

antiphospholipid syndrome (ISO)

aplastic anemia (ISO)

asthma (ISO)

atherosclerosis (ISO)

autistic disorder (ISO)

autoimmune disease (ISO)

autoimmune thrombocytopenic purpura (ISO)

autosomal hemophilia A (ISO)

B-Cell Chronic Lymphocytic Leukemia (ISO)

Behcet's disease (ISO)

Brain Injuries (ISO)

Calcification of Aortic Valve (ISO)

cardiovascular system disease (ISO)

carotid artery disease (ISO)

CD40 ligand deficiency (ISO)

Cholangiofibrosis (ISO)

Christianson syndrome (ISO)

Chromosome Breakage (ISO)

Chromosome Xq26.3 Duplication Syndrome (ISO)

Chronic Allograft Dysfunction (ISO)

chronic lymphocytic leukemia (ISO)

cocaine abuse (ISO)

Colonic Neoplasms (ISO)

combined T cell and B cell immunodeficiency (ISO)

common variable immunodeficiency (ISO)

congestive heart failure (ISO)

coronary artery disease (ISO)

Coronary Disease (ISO)

crescentic glomerulonephritis (ISO)

cutaneous lupus erythematosus (ISO)

cystic fibrosis (ISO)

dermatomyositis (ISO)

diabetes mellitus (ISO)

diabetic angiopathy (ISO)

Diabetic Nephropathies (ISO)

Discoid Lupus Erythematosus (ISO)

dysgammaglobulinemia (ISO)

Ehrlich tumor carcinoma (ISO)

end stage renal disease (ISO)

eosinophilic esophagitis (ISO)

erythema multiforme (ISO)

essential thrombocythemia (ISO)

Experimental Arthritis (ISO)

Experimental Autoimmune Myasthenia Gravis (ISO)

Experimental Autoimmune Neuritis (ISO)

Experimental Autoimmune Uveoretinitis (ISO)

Experimental Diabetes Mellitus (ISO)

Experimental Liver Neoplasms (ISO)

factor VIII deficiency (ISO)

familial hyperlipidemia (ISO)

Fibrosis (ISO)

follicular lymphoma (ISO)

genetic disease (ISO)

graft-versus-host disease (ISO)

granulomatosis with polyangiitis (ISO)

Graves' disease (ISO)

Hashimoto Disease (ISO)

HELLP syndrome (ISO)

hepatocellular carcinoma (ISO)

herpes simplex (ISO)

Hodgkin's lymphoma (ISO)

human immunodeficiency virus infectious disease (ISO)

Hypercholesterolemia (ISO)

inflammatory bowel disease (ISO)

Kawasaki disease (ISO)

kidney disease (ISO)

lichen planus (ISO)

lupus nephritis (ISO)

Lyme Neuroborreliosis (ISO)

malaria (ISO)

membranous glomerulonephritis (ISO)

Metabolic Syndrome (ISO)

Middle East respiratory syndrome (ISO)

migraine (ISO)

multiple myeloma (ISO)

Murine Acquired Immunodeficiency Syndrome (ISO)

myocardial infarction (ISO)

Myocardial Ischemia (ISO)

narcolepsy (ISO)

Necrosis (ISO)

nephrosis (ISO)

obesity (ISO)

ovarian disease (ISO)

Ovarian Neoplasms (ISO)

overactive bladder syndrome (ISO)

pemphigus (ISO)

Penetrating Wounds (ISO)

perinatal necrotizing enterocolitis (ISO)

periodontal disease (ISO)

periodontitis (ISO)

peritonitis (ISO)

pneumonia (ISO)

pre-eclampsia (ISO)

Primary Graft Dysfunction (ISO)

pulmonary hypertension (ISO)

Reperfusion Injury (ISO)

Sepsis (ISO)

Shock (ISO)

sickle cell anemia (ISO)

Sjogren's syndrome (ISO)

Subacute Combined Degeneration (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

systemic lupus erythematosus (ISO)

thrombocytopenia (ISO)

thrombosis (ISO)

tick-borne encephalitis (ISO)

transient cerebral ischemia (ISO)

Transplant Rejection (ISO)

type 1 diabetes mellitus (ISO)

type 2 diabetes mellitus (ISO)

urinary bladder cancer (ISO)

Vascular Calcification (ISO)

Viral Myocarditis (ISO)

visceral heterotaxy 1 (ISO)

visceral leishmaniasis (ISO)

vitamin B12 deficiency (ISO)

X-linked Emery-Dreifuss muscular dystrophy 6 (ISO)

X-linked hyper IgM syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

B cell differentiation (IEA)

B cell proliferation (IEA,ISS)

CD40 signaling pathway (IEA,ISO)

cell surface receptor signaling pathway (IBA)

cellular response to tumor necrosis factor (ISO)

dendritic cell differentiation (ISO)

immune response (IEA)

inflammatory response (IEA,ISS)

integrin-mediated signaling pathway (IEA)

isotype switching (IEA)

negative regulation of apoptotic process (IEA)

platelet activation (IEA,ISS)

positive regulation of B cell proliferation (ISO)

positive regulation of canonical NF-kappaB signal transduction (IBA)

positive regulation of dendritic cell differentiation (ISO)

positive regulation of endothelial cell apoptotic process (IEA)

positive regulation of extrinsic apoptotic signaling pathway (IBA)

positive regulation of gene expression (ISO)

positive regulation of immune response to tumor cell (ISO)

positive regulation of interleukin-10 production (IEA,ISO,ISS)

positive regulation of interleukin-12 production (IEA,ISO)

positive regulation of interleukin-4 production (IEA,ISS)

positive regulation of MHC class II biosynthetic process (ISO)

positive regulation of NF-kappaB transcription factor activity (ISS)

positive regulation of T cell proliferation (IEA,ISS)

positive regulation of type II interferon production (ISO)

regulation of gene expression (IEA)

regulation of immune system process (IEA)

regulation of immunoglobulin production (IEA)

response to cobalamin (ISO)

response to peptide (ISO)

signal transduction (IEA)

Cellular Component

cell body (ISO)

cell projection (ISO)

cell surface (IEA,ISO,ISS)

external side of plasma membrane (IEA)

extracellular region (IEA)

extracellular space (IBA,IEA,ISO)

Golgi apparatus (IEA)

membrane (IEA)

plasma membrane (IEA)

Molecular Function

CD40 receptor binding (IEA,ISO,ISS)

cytokine activity (IBA,IEA)

integrin binding (IEA)

protein binding (ISO)

protein serine/threonine kinase activator activity (IEA,ISS)

tumor necrosis factor receptor binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

interleukin-4 signaling pathway (ISO)

obesity pathway (ISO)

References

Additional References at PubMed

PMID:18658029	PMID:22301074

Genomics

Comparative Map Data

CD40LG
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	111,778,493 - 111,789,709 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	111,778,666 - 111,788,901 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	127,636,797 - 127,647,035 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CD40LG
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	136,648,158 - 136,660,390 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	136,648,158 - 136,660,390 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	135,730,317 - 135,742,549 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	135,558,002 - 135,570,215 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	135,455,855 - 135,468,068	NCBI
Celera	X	136,094,012 - 136,106,224 (+)	NCBI		Celera
Cytogenetic Map	X	q26.3	NCBI
HuRef	X	125,001,305 - 125,013,640 (+)	NCBI		HuRef
CHM1_1	X	135,641,985 - 135,654,211 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	134,956,900 - 134,969,116 (+)	NCBI		T2T-CHM13v2.0

Cd40lg
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	56,257,448 - 56,269,402 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	56,257,503 - 56,269,402 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	57,212,143 - 57,224,042 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	57,212,143 - 57,224,042 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	54,465,320 - 54,477,219 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	53,558,927 - 53,570,826 (+)	NCBI		MGSCv36	mm8
Celera	X	43,689,623 - 43,701,548 (+)	NCBI		Celera
Cytogenetic Map	X	A6	NCBI
cM Map	X	31.21	NCBI

Cd40lg
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	140,164,341 - 140,176,057 (+)	NCBI		GRCr8
GRCr8 Ensembl	X	140,164,302 - 140,176,475 (+)	Ensembl		GRCr8 Ensembl
mRatBN7.2	X	135,127,052 - 135,138,768 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	135,126,969 - 135,138,306 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	137,323,952 - 137,335,135 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	140,881,620 - 140,892,805 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	138,451,019 - 138,462,204 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	159,703,703 - 159,714,886 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	159,703,578 - 159,716,562 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	154,330,893 - 154,341,954 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	141,925,019 - 141,937,183 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	143,160,596 - 143,171,765 (+)	NCBI		Celera
RGSC_v3.1	X	141,998,451 - 142,010,616 (+)	NCBI
Cytogenetic Map	X	q36	NCBI

Cd40lg
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955489	8,465,164 - 8,477,746 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955489	8,465,571 - 8,477,714 (-)	NCBI	ChiLan1.0	ChiLan1.0

CD40LG
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	136,065,286 - 136,078,025 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	136,068,886 - 136,081,625 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	125,776,138 - 125,788,820 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	136,042,849 - 136,055,158 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	136,042,849 - 136,058,202 (+)	Ensembl	panpan1.1		panPan2

CD40LG
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	107,001,421 - 107,023,007 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	107,010,890 - 107,023,006 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	92,832,126 - 92,844,241 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	108,980,873 - 109,002,662 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	108,990,551 - 109,002,661 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	106,131,221 - 106,143,392 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	108,322,638 - 108,334,748 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	107,964,432 - 107,976,548 (+)	NCBI		UU_Cfam_GSD_1.0

Cd40lg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	104,994,220 - 105,007,112 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936513	10,607,617 - 10,620,403 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936513	10,607,617 - 10,620,403 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CD40LG
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	111,655,301 - 111,667,602 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	111,655,397 - 111,666,639 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	49,341,810 - 49,354,077 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cd40lg
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624808	10,472,572 - 10,484,338 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624808	10,472,028 - 10,484,407 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in CD40LG
156 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
10	2	5	1	2	5	8	7	5	1	3	3

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_214126	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB040443	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AEMK02000122	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF263915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01096816	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HQ110108	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000027452 ⟹ ENSSSCP00000020229

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	X	111,778,493 - 111,789,709 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000073417 ⟹ ENSSSCP00000065230

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	X	111,778,493 - 111,788,901 (+)	Ensembl

RefSeq Acc Id:

NM_214126 ⟹ NP_999291

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	X	111,778,666 - 111,788,901 (+)	NCBI

Sequence:

show sequence

ATGATCGAAACGTACAGCCAACCTTCGCCCCGCTCTGTGGCCGCTGGACCACCCGTCAGTATGA
AAATCTTTATGTATTTACTTACTGTTTTTCTTATCACCCAGATGATTGGGTCAGCACTTTTTGC
AGCGTACCTTCACAGAAGATTGGACAAGATAGAAGATGAAAGGAATCTTCATGAAGATTTTGTG
TTCATAAAAACGATACAGAGATGCAAGCAAGGAGAGGGGTCCTTATCCTTATTGAACTGTGAGG
AAATCAGAAGCCAGTTTGAAGACCTGGTCAAGGGTATAATGCAAAGCAAAGAAGTGAAGAAGAA
AGAAAAAAGCTTTGAAATGCACAAAGGCGATCAGGATCCTCAAATTGCGGCACATGTCATAAGC
GAGGCCAGTAGTAAAACAGCATCTGTCCTGCAGTGGGCCCCCAAAGGGTACTACACCCTCAGCA
CCAACTTGGTGACCCTGGAAAACGGGAGACAGCTGGCCGTCAAAAGACAAGGAATCTATTACAT
CTACGCCCAAGTCACCTTCTGCTCCAACCGGGACGCCGCGGGTCAAGCTCCCTTCATAGCCAGC
CTCTGCCTGAGGTCCCCAAGCGGGTCGGAGAGAATCTTACTCCGCGCGGCCAACACCCACAGTT
CCTCCAAGCCCTGCGGGCAGCAATCCATTCACTTGGGCGGAGTCTTCGAGTTGCAACCCGGCGC
TTCGGTGTTCGTCAACGTGACTGATCCAAGCCAAGTGAGCCACGGGACCGGCTTCACGTCTTTT
GGCCTCCTCAAACTCTGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_999291	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAK58524	(Get FASTA)	NCBI Sequence Viewer
	ADM26719	(Get FASTA)	NCBI Sequence Viewer
	BAB86593	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000020229
GenBank Protein	Q95MQ5	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_999291 ⟸ NM_214126

- UniProtKB:

Q95MQ5 (UniProtKB/Swiss-Prot), E1AXT9 (UniProtKB/TrEMBL), A0A4X1TUU8 (UniProtKB/TrEMBL), A0A5G2QL03 (UniProtKB/TrEMBL), A0A8D0WXV7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MIETYSQPSPRSVAAGPPVSMKIFMYLLTVFLITQMIGSALFAAYLHRRLDKIEDERNLHEDFV
FIKTIQRCKQGEGSLSLLNCEEIRSQFEDLVKGIMQSKEVKKKEKSFEMHKGDQDPQIAAHVIS
EASSKTASVLQWAPKGYYTLSTNLVTLENGRQLAVKRQGIYYIYAQVTFCSNRDAAGQAPFIAS
LCLRSPSGSERILLRAANTHSSSKPCGQQSIHLGGVFELQPGASVFVNVTDPSQVSHGTGFTSF
GLLKL

hide sequence

Ensembl Acc Id:

ENSSSCP00000065230 ⟸ ENSSSCT00000073417

Ensembl Acc Id:

ENSSSCP00000020229 ⟸ ENSSSCT00000027452

Protein Domains

THD

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000030172	Ensembl, ENTREZGENE
Ensembl Transcript	ENSSSCT00000027452	ENTREZGENE
Gene3D-CATH	2.60.120.40	UniProtKB/Swiss-Prot
InterPro	CD40L	UniProtKB/Swiss-Prot
	TNF_CS	UniProtKB/Swiss-Prot
	TNF_dom	UniProtKB/Swiss-Prot
	Tumour_necrosis_fac-like_dom	UniProtKB/Swiss-Prot
KEGG Report	ssc:397231	UniProtKB/Swiss-Prot
NCBI Gene	CD40LG	ENTREZGENE
PANTHER	PTHR11471:SF5	UniProtKB/Swiss-Prot
	TUMOR NECROSIS FACTOR FAMILY MEMBER	UniProtKB/Swiss-Prot
Pfam	TNF	UniProtKB/Swiss-Prot
PIRSF	TNF_5	UniProtKB/Swiss-Prot
PRINTS	CD40LIGAND	UniProtKB/Swiss-Prot
PROSITE	TNF_1	UniProtKB/Swiss-Prot
	TNF_2	UniProtKB/Swiss-Prot
SMART	TNF	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF49842	UniProtKB/Swiss-Prot
UniProt	A0A4X1TUU8	ENTREZGENE, UniProtKB/TrEMBL
	A0A5G2QL03	ENTREZGENE
	A0A8D0WXV7	ENTREZGENE, UniProtKB/TrEMBL
	CD40L_PIG	UniProtKB/Swiss-Prot
	E1AXT9	ENTREZGENE, UniProtKB/TrEMBL
	I3L871_PIG	UniProtKB/TrEMBL
	Q95MQ5	ENTREZGENE
VGNC ID	VGNC:86418	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)