MYOD1 (myogenic differentiation 1) - Rat Genome Database

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Gene: MYOD1 (myogenic differentiation 1) Sus scrofa
Analyze
Symbol: MYOD1
Name: myogenic differentiation 1
RGD ID: 13894302
Description: ENCODES a protein that exhibits chromatin binding (ortholog); chromatin DNA binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to estradiol stimulus (ortholog); cellular response to glucocorticoid stimulus (ortholog); cellular response to oxygen levels (ortholog); ASSOCIATED WITH centronuclear myopathy 1 (ortholog); congenital diaphragmatic hernia (ortholog); congestive heart failure (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: eukaryotic myogenic factor MYF-3; MUF3; MYF-3; myoblast determination protein 1; MYOD; myogenic factor 3; myogenic regulatory factor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl241,415,735 - 41,425,234 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1241,422,522 - 41,424,236 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2244,483,015 - 44,484,730 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to estradiol stimulus  (IEA,ISS)
cellular response to glucocorticoid stimulus  (IEA,ISO)
cellular response to oxygen levels  (IEA,ISO)
cellular response to starvation  (IEA,ISO)
cellular response to tumor necrosis factor  (IEA,ISO)
histone H3 acetylation  (IEA,ISS)
histone H4 acetylation  (IEA,ISS)
muscle organ development  (ISO,ISS)
myoblast differentiation  (ISO,ISS)
myoblast fate determination  (IEA,ISO,ISS)
myoblast fusion  (IEA,ISO)
myotube cell development  (ISO)
myotube differentiation  (ISO)
myotube differentiation involved in skeletal muscle regeneration  (IEA,ISO)
negative regulation of chromatin binding  (IEA)
negative regulation of myoblast proliferation  (IEA,ISO)
positive regulation of binding  (IEA)
positive regulation of muscle cell differentiation  (ISS)
positive regulation of myoblast differentiation  (IBA)
positive regulation of myoblast fusion  (IEA)
positive regulation of skeletal muscle fiber development  (IBA)
positive regulation of skeletal muscle tissue regeneration  (IEA,ISO,ISS)
positive regulation of snRNA transcription by RNA polymerase II  (IEA,ISS)
positive regulation of transcription by RNA polymerase II  (ISO,ISS)
positive regulation of transcription, DNA-templated  (ISO)
regulation of alternative mRNA splicing, via spliceosome  (IEA,ISO,ISS)
regulation of gene expression  (ISO)
regulation of RNA splicing  (ISO)
regulation of transcription by RNA polymerase II  (IBA,ISO)
response to muscle stretch  (ISO)
skeletal muscle atrophy  (ISO)
skeletal muscle cell differentiation  (IBA,ISO)
skeletal muscle fiber adaptation  (IEA,ISO)
skeletal muscle fiber development  (IEA,ISO)
skeletal muscle tissue development  (ISO,ISS)
skeletal muscle tissue regeneration  (ISO)
striated muscle cell differentiation  (ISO,ISS)
transcription, DNA-templated  (ISS)

Cellular Component

References
Additional References at PubMed
PMID:7559997   PMID:9124704   PMID:9525963   PMID:11711431   PMID:12037571   PMID:12486129   PMID:14762206   PMID:15306724   PMID:15520228   PMID:17028574   PMID:18462612   PMID:18777094  
PMID:20336382   PMID:20888930   PMID:22554470   PMID:25377122   PMID:25646693   PMID:25966141   PMID:26944559   PMID:32121115  


Genomics

Comparative Map Data
MYOD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl241,415,735 - 41,425,234 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1241,422,522 - 41,424,236 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2244,483,015 - 44,484,730 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYOD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1117,719,571 - 17,722,136 (+)EnsemblGRCh38hg38GRCh38
GRCh381117,719,571 - 17,722,136 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371117,741,118 - 17,743,683 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361117,697,686 - 17,700,254 (+)NCBINCBI36hg18NCBI36
Build 341117,697,734 - 17,700,254NCBI
Celera1117,873,623 - 17,876,191 (+)NCBI
Cytogenetic Map11p15.1NCBI
HuRef1117,425,110 - 17,427,678 (+)NCBIHuRef
CHM1_11117,740,837 - 17,743,405 (+)NCBICHM1_1
Myod1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39746,025,898 - 46,028,516 (+)NCBIGRCm39mm39
GRCm39 Ensembl746,025,898 - 46,028,523 (+)Ensembl
GRCm38746,376,474 - 46,379,092 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl746,376,474 - 46,379,099 (+)EnsemblGRCm38mm10GRCm38
MGSCv37753,631,844 - 53,634,462 (+)NCBIGRCm37mm9NCBIm37
MGSCv36746,244,524 - 46,247,137 (+)NCBImm8
Celera741,849,969 - 41,852,587 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map730.03NCBI
Myod1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2196,884,864 - 96,887,574 (+)NCBI
Rnor_6.0 Ensembl1102,396,538 - 102,399,248 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01102,396,538 - 102,399,248 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01103,481,604 - 103,484,314 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,910,190 - 96,912,900 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1196,988,300 - 96,991,011 (+)NCBI
Celera191,133,211 - 91,135,921 (+)NCBICelera
Cytogenetic Map1q22NCBI
Myod1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541432,523,924 - 32,526,674 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541432,523,959 - 32,526,575 (+)NCBIChiLan1.0ChiLan1.0
MYOD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11117,456,124 - 17,458,690 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1117,456,124 - 17,458,690 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01117,772,317 - 17,774,884 (+)NCBIMhudiblu_PPA_v0panPan3
MYOD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12140,257,792 - 40,260,461 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2140,258,027 - 40,259,712 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2139,757,431 - 39,759,334 (+)NCBI
ROS_Cfam_1.02141,362,253 - 41,364,156 (+)NCBI
UMICH_Zoey_3.12140,375,120 - 40,377,023 (+)NCBI
UNSW_CanFamBas_1.02140,582,881 - 40,584,784 (+)NCBI
UU_Cfam_GSD_1.02140,921,445 - 40,923,349 (+)NCBI
Myod1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494745,372,988 - 45,375,811 (-)NCBI
SpeTri2.0NW_0049365281,407,187 - 1,409,683 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103239432
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1147,250,927 - 47,254,572 (-)NCBI
ChlSab1.1 Ensembl147,251,551 - 47,253,284 (-)Ensembl
Vero_WHO_p1.0NW_023666038144,644,005 - 144,646,580 (-)NCBI
Myod1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247669,345,390 - 9,347,985 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

musculoskeletal system
High
Medium 2
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000014609   ⟹   ENSSSCP00000014214
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl241,415,735 - 41,425,234 (-)Ensembl
RefSeq Acc Id: NM_001002824   ⟹   NP_001002824
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1241,422,522 - 41,424,236 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001002824 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA87061 (Get FASTA)   NCBI Sequence Viewer  
  AAT66424 (Get FASTA)   NCBI Sequence Viewer  
  ADA82236 (Get FASTA)   NCBI Sequence Viewer  
  P49811 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001002824   ⟸   NM_001002824
- UniProtKB: P49811 (UniProtKB/Swiss-Prot),   D2KPI9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000014214   ⟸   ENSSSCT00000014609
Protein Domains
bHLH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000013375 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000014214 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000014609 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Basic UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myf5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myogenic_factor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:407604 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene MYOD1 ENTREZGENE
PANTHER PTHR11534 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Basic UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myf5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BASIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D2KPI9 ENTREZGENE, UniProtKB/TrEMBL
  F1S9A9_PIG UniProtKB/TrEMBL
  MYOD1_PIG UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:90537 ENTREZGENE