MYOG (myogenin) - Rat Genome Database

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Gene: MYOG (myogenin) Sus scrofa
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Symbol: MYOG
Name: myogenin
RGD ID: 14235560
Description: ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to growth factor stimulus (ortholog); cellular response to lithium ion (ortholog); cellular response to magnetism (ortholog); ASSOCIATED WITH Experimental Arthritis (ortholog); Experimental Autoimmune Myasthenia Gravis (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN nucleus (ortholog); protein-DNA complex (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: myogenin factor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9113,782,469 - 113,785,362 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19113,783,233 - 113,785,312 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29125,243,803 - 125,245,882 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap9q2.1-q2.6NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to estradiol stimulus  (IEA)
cellular response to growth factor stimulus  (IEA,ISO)
cellular response to lithium ion  (IEA,ISO)
cellular response to magnetism  (ISO)
cellular response to retinoic acid  (ISO)
cellular response to tumor necrosis factor  (IEA,ISO)
histone H3 acetylation  (ISO)
histone H4 acetylation  (ISO)
muscle cell differentiation  (ISO)
muscle organ development  (ISO)
myoblast differentiation  (ISO)
myotube differentiation  (ISO)
negative regulation of cell population proliferation  (IEA)
negative regulation of glycolytic process  (ISO)
ossification  (IEA,ISO)
positive regulation of muscle atrophy  (IEA)
positive regulation of myoblast differentiation  (IEA)
positive regulation of myotube differentiation  (IEA)
positive regulation of oxidative phosphorylation  (ISO)
positive regulation of skeletal muscle fiber development  (IEA)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
positive regulation of transcription, DNA-templated  (ISO)
regulation of cell cycle  (IEA)
regulation of myoblast fusion  (IEA)
regulation of skeletal muscle satellite cell proliferation  (IEA)
response to denervation involved in regulation of muscle adaptation  (IEA)
response to electrical stimulus involved in regulation of muscle adaptation  (ISO)
response to gravity  (ISO)
response to muscle activity  (ISO)
response to muscle activity involved in regulation of muscle adaptation  (ISO)
skeletal muscle atrophy  (ISO)
skeletal muscle fiber development  (IEA,ISO)
skeletal muscle tissue development  (ISO)
skeletal muscle tissue regeneration  (ISO)
striated muscle atrophy  (IEA)

Cellular Component

References
Additional References at PubMed
PMID:9250861   PMID:9464916   PMID:10492439   PMID:16682754   PMID:17112970   PMID:18462612   PMID:20640787   PMID:28799830  


Genomics

Comparative Map Data
MYOG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9113,782,469 - 113,785,362 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19113,783,233 - 113,785,312 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29125,243,803 - 125,245,882 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap9q2.1-q2.6NCBI
MYOG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1203,083,129 - 203,086,012 (-)EnsemblGRCh38hg38GRCh38
GRCh381203,083,129 - 203,086,012 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371203,052,257 - 203,055,140 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361201,318,880 - 201,322,000 (-)NCBINCBI36hg18NCBI36
Build 341199,783,916 - 199,786,823NCBI
Celera1176,181,515 - 176,184,632 (-)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1174,217,862 - 174,220,769 (-)NCBIHuRef
CHM1_11204,474,600 - 204,477,509 (-)NCBICHM1_1
Myog
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,217,742 - 134,220,286 (+)NCBIGRCm39mm39
GRCm39 Ensembl1134,217,727 - 134,220,286 (+)Ensembl
GRCm381134,290,004 - 134,292,548 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,289,989 - 134,292,548 (+)EnsemblGRCm38mm10GRCm38
MGSCv371136,186,581 - 136,189,125 (+)NCBIGRCm37mm9NCBIm37
MGSCv361136,106,424 - 136,108,961 (+)NCBImm8
Celera1136,900,556 - 136,903,100 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.18NCBI
Myog
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21345,745,455 - 45,748,044 (+)NCBI
Rnor_6.0 Ensembl1351,126,459 - 51,129,048 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01351,126,459 - 51,129,048 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01356,182,747 - 56,185,336 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41347,243,712 - 47,246,301 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11347,257,754 - 47,260,344 (+)NCBI
Celera1346,073,572 - 46,076,161 (+)NCBICelera
Cytogenetic Map13q13NCBI
Myog
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540639,099,716 - 39,102,501 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540639,099,044 - 39,102,479 (-)NCBIChiLan1.0ChiLan1.0
MYOG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11182,979,700 - 182,982,607 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1182,979,700 - 182,982,611 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01178,684,933 - 178,687,971 (-)NCBIMhudiblu_PPA_v0panPan3
MYOG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.17112,116 - 114,604 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl7112,034 - 113,892 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha7167,989 - 170,338 (+)NCBI
ROS_Cfam_1.07122,772 - 125,124 (+)NCBI
UMICH_Zoey_3.17111,008 - 113,379 (+)NCBI
UNSW_CanFamBas_1.07220,521 - 222,887 (+)NCBI
UU_Cfam_GSD_1.07243,050 - 245,421 (+)NCBI
Myog
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934472,272,365 - 72,275,138 (+)NCBI
SpeTri2.0NW_0049365671,507,042 - 1,509,814 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYOG
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12526,264,872 - 26,269,652 (+)NCBI
ChlSab1.1 Ensembl2526,266,717 - 26,268,867 (+)Ensembl
Vero_WHO_p1.0NW_02366605527,042,619 - 27,045,566 (+)NCBI
Myog
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248077,742,926 - 7,753,149 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system reproductive system respiratory system
High
Medium 1
Low 2 1 3 3 1 20 1
Below cutoff 6 3 2 3 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001012406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY642156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY902465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY912510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY912511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY912512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY912513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY912514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY921004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY921005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY921006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY921007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU694815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ356697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U14331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X89007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000065761   ⟹   ENSSSCP00000047674
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9113,782,469 - 113,785,362 (-)Ensembl
RefSeq Acc Id: NM_001012406   ⟹   NP_001012406
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.19113,783,233 - 113,785,312 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001012406   ⟸   NM_001012406
- UniProtKB: P49812 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000047674   ⟸   ENSSSCT00000065761
Protein Domains
bHLH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000034654 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005039937 UniProtKB/Swiss-Prot
  ENSSSCG00015058439 UniProtKB/Swiss-Prot
  ENSSSCG00030030487 UniProtKB/Swiss-Prot
  ENSSSCG00035049918 UniProtKB/Swiss-Prot
  ENSSSCG00040070604 UniProtKB/Swiss-Prot
  ENSSSCG00045031101 UniProtKB/Swiss-Prot
  ENSSSCG00050071960 UniProtKB/Swiss-Prot
  ENSSSCG00055010529 UniProtKB/Swiss-Prot
  ENSSSCG00065038287 UniProtKB/Swiss-Prot
  ENSSSCG00070018146 UniProtKB/Swiss-Prot
Ensembl Protein ENSSSCP00000047674 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00005039488 UniProtKB/Swiss-Prot
  ENSSSCP00015031453 UniProtKB/Swiss-Prot
  ENSSSCP00030019244 UniProtKB/Swiss-Prot
  ENSSSCP00035026973 UniProtKB/Swiss-Prot
  ENSSSCP00040043127 UniProtKB/Swiss-Prot
  ENSSSCP00045036883 UniProtKB/Swiss-Prot
  ENSSSCP00050042403 UniProtKB/Swiss-Prot
  ENSSSCP00055016278 UniProtKB/Swiss-Prot
  ENSSSCP00065022747 UniProtKB/Swiss-Prot
  ENSSSCP00070029919 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000065761 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00005063907 UniProtKB/Swiss-Prot
  ENSSSCT00015078006 UniProtKB/Swiss-Prot
  ENSSSCT00030042324 UniProtKB/Swiss-Prot
  ENSSSCT00035066513 UniProtKB/Swiss-Prot
  ENSSSCT00040096902 UniProtKB/Swiss-Prot
  ENSSSCT00045053016 UniProtKB/Swiss-Prot
  ENSSSCT00050098218 UniProtKB/Swiss-Prot
  ENSSSCT00055020596 UniProtKB/Swiss-Prot
  ENSSSCT00065052332 UniProtKB/Swiss-Prot
  ENSSSCT00070035804 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Basic UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myogenic_factor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:497618 UniProtKB/Swiss-Prot
NCBI Gene MYOG ENTREZGENE
PANTHER PTHR11534 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Basic UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BASIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A5S6HX62_PIG UniProtKB/TrEMBL
  E1U5T0_PIG UniProtKB/TrEMBL
  MYOG_PIG UniProtKB/Swiss-Prot, ENTREZGENE
  Q6DUX7_PIG UniProtKB/TrEMBL
UniProt Secondary Q5EC23 UniProtKB/Swiss-Prot
  Q5EE03 UniProtKB/Swiss-Prot
VGNC ID VGNC:90539 ENTREZGENE