CYP2R1 (cytochrome P450 family 2 subfamily R member 1) - Rat Genome Database

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Gene: CYP2R1 (cytochrome P450 family 2 subfamily R member 1) Sus scrofa
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Symbol: CYP2R1
Name: cytochrome P450 family 2 subfamily R member 1
RGD ID: 14241303
Description: ENCODES a protein that exhibits D3 vitamins binding (inferred); heme binding (inferred); iron ion binding (inferred); INVOLVED IN response to cesium ion (ortholog); response to ionizing radiation (ortholog); response to metal ion (ortholog); ASSOCIATED WITH intellectual disability (ortholog); liver cirrhosis (ortholog); Metabolic Bone Diseases (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cytochrome P450 2R1; cytochrome P450, family 2, subfamily R, polypeptide 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl244,375,520 - 44,396,367 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1244,375,432 - 44,394,122 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2247,676,732 - 47,695,293 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
CYP2R1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl244,375,520 - 44,396,367 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1244,375,432 - 44,394,122 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2247,676,732 - 47,695,293 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CYP2R1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381114,877,440 - 14,892,443 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1114,877,440 - 14,892,231 (-)EnsemblGRCh38hg38GRCh38
GRCh371114,898,986 - 14,913,989 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361114,856,131 - 14,870,327 (-)NCBINCBI36hg18NCBI36
Build 341114,856,183 - 14,870,327NCBI
Celera1115,026,672 - 15,040,868 (-)NCBI
Cytogenetic Map11p15.2NCBI
HuRef1114,581,996 - 14,596,194 (-)NCBIHuRef
CHM1_11114,898,541 - 14,912,738 (-)NCBICHM1_1
T2T-CHM13v2.01114,973,806 - 14,988,811 (-)NCBI
Cyp2r1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397114,149,358 - 114,162,283 (-)NCBIGRCm39mm39
GRCm39 Ensembl7114,148,917 - 114,162,207 (-)Ensembl
GRCm387114,550,123 - 114,563,048 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7114,549,682 - 114,562,972 (-)EnsemblGRCm38mm10GRCm38
MGSCv377121,693,680 - 121,706,486 (-)NCBIGRCm37mm9NCBIm37
MGSCv367114,341,347 - 114,354,153 (-)NCBImm8
Celera7114,506,181 - 114,518,984 (-)NCBICelera
Cytogenetic Map7F1NCBI
Cyp2r1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21168,749,302 - 168,798,079 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1168,751,038 - 168,797,759 (-)Ensembl
Rnor_6.01184,060,521 - 184,106,604 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1184,093,920 - 184,106,200 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01191,032,655 - 191,078,746 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41172,593,057 - 172,605,512 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11172,729,161 - 172,741,682 (-)NCBI
Celera1166,625,863 - 166,638,315 (-)NCBICelera
Cytogenetic Map1q34NCBI
LOC102024786
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541429,928,644 - 29,948,484 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541429,929,130 - 29,948,151 (-)NCBIChiLan1.0ChiLan1.0
CYP2R1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11114,656,939 - 14,671,584 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1114,656,939 - 14,671,584 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01114,960,651 - 14,989,083 (-)NCBIMhudiblu_PPA_v0panPan3
CYP2R1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12137,553,883 - 37,579,744 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2137,552,732 - 37,606,725 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2137,053,097 - 37,079,853 (-)NCBI
ROS_Cfam_1.02138,647,594 - 38,674,701 (-)NCBI
ROS_Cfam_1.0 Ensembl2138,649,539 - 38,674,887 (-)Ensembl
LOC101972957
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494747,848,045 - 47,866,726 (+)NCBI
SpeTri2.0NW_0049365283,881,630 - 3,897,613 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYP2R1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1150,030,366 - 50,043,833 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl150,031,218 - 50,047,403 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038147,527,420 - 147,540,720 (+)NCBIVero_WHO_p1.0
LOC101724787
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247666,667,234 - 6,677,992 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247666,667,662 - 6,678,045 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1
Low 9 3 3 5 2 23 2 3 1
Below cutoff 1 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000014625   ⟹   ENSSSCP00000014230
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl244,384,567 - 44,394,106 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000036906   ⟹   ENSSSCP00000034261
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl244,375,520 - 44,396,367 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000052930   ⟹   ENSSSCP00000041374
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl244,375,520 - 44,396,322 (+)Ensembl
RefSeq Acc Id: XM_003480731   ⟹   XP_003480779
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1244,375,432 - 44,394,122 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003480779 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABS58487 (Get FASTA)   NCBI Sequence Viewer  
  AKO62662 (Get FASTA)   NCBI Sequence Viewer  
  AKO62667 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003480779   ⟸   XM_003480731
- Sequence:
RefSeq Acc Id: ENSSSCP00000041374   ⟸   ENSSSCT00000052930
RefSeq Acc Id: ENSSSCP00000034261   ⟸   ENSSSCT00000036906
RefSeq Acc Id: ENSSSCP00000014230   ⟸   ENSSSCT00000014625


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000013389 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00005043266 UniProtKB/TrEMBL
  ENSSSCG00015008435 UniProtKB/TrEMBL
  ENSSSCG00025071970 UniProtKB/TrEMBL
  ENSSSCG00030021055 UniProtKB/TrEMBL
  ENSSSCG00035004197 UniProtKB/TrEMBL
  ENSSSCG00040010502 UniProtKB/TrEMBL
  ENSSSCG00045017894 UniProtKB/TrEMBL
  ENSSSCG00050022932 UniProtKB/TrEMBL
  ENSSSCG00055028058 UniProtKB/TrEMBL
  ENSSSCG00060022679 UniProtKB/TrEMBL
  ENSSSCG00065044668 UniProtKB/TrEMBL
  ENSSSCG00070009653 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000014230 UniProtKB/TrEMBL
  ENSSSCP00000034261 UniProtKB/TrEMBL
  ENSSSCP00000041374 UniProtKB/TrEMBL
  ENSSSCP00005043223 UniProtKB/TrEMBL
  ENSSSCP00005043252 UniProtKB/TrEMBL
  ENSSSCP00015004395 UniProtKB/TrEMBL
  ENSSSCP00015004423 UniProtKB/TrEMBL
  ENSSSCP00025043524 UniProtKB/TrEMBL
  ENSSSCP00025043562 UniProtKB/TrEMBL
  ENSSSCP00030013090 UniProtKB/TrEMBL
  ENSSSCP00030013097 UniProtKB/TrEMBL
  ENSSSCP00035001813 UniProtKB/TrEMBL
  ENSSSCP00035001816 UniProtKB/TrEMBL
  ENSSSCP00040005225 UniProtKB/TrEMBL
  ENSSSCP00040005247 UniProtKB/TrEMBL
  ENSSSCP00045021133 UniProtKB/TrEMBL
  ENSSSCP00045021186 UniProtKB/TrEMBL
  ENSSSCP00050012923 UniProtKB/TrEMBL
  ENSSSCP00050012933 UniProtKB/TrEMBL
  ENSSSCP00055044376 UniProtKB/TrEMBL
  ENSSSCP00055044420 UniProtKB/TrEMBL
  ENSSSCP00060013228 UniProtKB/TrEMBL
  ENSSSCP00060013229 UniProtKB/TrEMBL
  ENSSSCP00065026468 UniProtKB/TrEMBL
  ENSSSCP00065026469 UniProtKB/TrEMBL
  ENSSSCP00070015547 UniProtKB/TrEMBL
  ENSSSCP00070015550 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000014625 UniProtKB/TrEMBL
  ENSSSCT00000036906 UniProtKB/TrEMBL
  ENSSSCT00000052930 UniProtKB/TrEMBL
  ENSSSCT00005069481 UniProtKB/TrEMBL
  ENSSSCT00005069523 UniProtKB/TrEMBL
  ENSSSCT00015011162 UniProtKB/TrEMBL
  ENSSSCT00015011228 UniProtKB/TrEMBL
  ENSSSCT00025098953 UniProtKB/TrEMBL
  ENSSSCT00025099031 UniProtKB/TrEMBL
  ENSSSCT00030029180 UniProtKB/TrEMBL
  ENSSSCT00030029191 UniProtKB/TrEMBL
  ENSSSCT00035005233 UniProtKB/TrEMBL
  ENSSSCT00035005238 UniProtKB/TrEMBL
  ENSSSCT00040013648 UniProtKB/TrEMBL
  ENSSSCT00040013683 UniProtKB/TrEMBL
  ENSSSCT00045030499 UniProtKB/TrEMBL
  ENSSSCT00045030575 UniProtKB/TrEMBL
  ENSSSCT00050030968 UniProtKB/TrEMBL
  ENSSSCT00050030987 UniProtKB/TrEMBL
  ENSSSCT00055055599 UniProtKB/TrEMBL
  ENSSSCT00055055658 UniProtKB/TrEMBL
  ENSSSCT00060030800 UniProtKB/TrEMBL
  ENSSSCT00060030805 UniProtKB/TrEMBL
  ENSSSCT00065061104 UniProtKB/TrEMBL
  ENSSSCT00065061108 UniProtKB/TrEMBL
  ENSSSCT00070018709 UniProtKB/TrEMBL
  ENSSSCT00070018714 UniProtKB/TrEMBL
Gene3D-CATH 1.10.630.10 UniProtKB/TrEMBL
InterPro Cyt_P450 UniProtKB/TrEMBL
  Cyt_P450_CS UniProtKB/TrEMBL
  Cyt_P450_E_grp-I UniProtKB/TrEMBL
  Cyt_P450_sf UniProtKB/TrEMBL
KEGG Report ssc:100124375 UniProtKB/TrEMBL
NCBI Gene CYP2R1 ENTREZGENE
Pfam p450 UniProtKB/TrEMBL
PRINTS EP450I UniProtKB/TrEMBL
  P450 UniProtKB/TrEMBL
PROSITE CYTOCHROME_P450 UniProtKB/TrEMBL
Superfamily-SCOP SSF48264 UniProtKB/TrEMBL
UniProt A0A0H4ITY0_PIG UniProtKB/TrEMBL
  A0A0H4ITY4_PIG UniProtKB/TrEMBL
  A0A286ZS13_PIG UniProtKB/TrEMBL
  A0A287ABJ2_PIG UniProtKB/TrEMBL
  A0A4X1TKA0_PIG UniProtKB/TrEMBL
  A0A4X1TKK9_PIG UniProtKB/TrEMBL
  A7KZR1_PIG UniProtKB/TrEMBL
  F1S984_PIG UniProtKB/TrEMBL
VGNC ID VGNC:103552 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-21 CYP2R1  cytochrome P450 family 2 subfamily R member 1  CYP2R1  cytochrome P450, family 2, subfamily R, polypeptide 1  Symbol and/or name change 19259463 PROVISIONAL