NOS3 (nitric oxide synthase 3) - Rat Genome Database

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Gene: NOS3 (nitric oxide synthase 3) Sus scrofa
Analyze
Symbol: NOS3
Name: nitric oxide synthase 3
RGD ID: 14180349
Description: ENCODES a protein that exhibits actin binding (ortholog); beta-catenin binding (ortholog); cadherin binding (ortholog); INVOLVED IN vasodilation; aging (ortholog); angiogenesis (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics pathway; eicosanoid signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH acute chest syndrome (ortholog); acute kidney failure (ortholog); Acute Liver Failure (ortholog); FOUND IN apical part of cell (ortholog); caveola (ortholog); cytoplasm (ortholog); INTERACTS WITH 11-deoxyprostaglandin E1; 16,16-dimethylprostaglandin E2; 17beta-estradiol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cNOS; constitutive NOS; EC-NOS; endothelial nitric oxide synthase; endothelial NOS; eNOS; nitric oxide synthase, endothelial; NOS; NOS type III; NOSIII
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl186,209,156 - 6,228,938 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1186,209,218 - 6,228,912 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,579,253 - 6,602,572 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute chest syndrome  (ISO)
acute kidney failure  (ISO)
Acute Liver Failure  (ISO)
acute lymphoblastic leukemia  (ISO)
acute myeloid leukemia  (ISO)
adenocarcinoma  (ISO)
Alzheimer's disease  (ISO)
Alzheimer's disease 1  (ISO)
angle-closure glaucoma  (ISO)
anterior ischemic optic neuropathy  (ISO)
arteriosclerosis  (ISO)
Arteriovenous Fistula  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
atrial fibrillation  (ISO)
Behcet's disease  (ISO)
bladder neck obstruction  (ISO)
Brain Hypoxia  (ISO)
brain ischemia  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
Bronchial Hyperreactivity  (ISO)
bronchiolitis obliterans  (ISO)
Cardiomegaly  (ISO)
cardiomyopathy  (ISO)
Cardiotoxicity  (ISO)
cardiovascular system disease  (ISO)
Carotid Artery Injuries  (ISO)
central sleep apnea  (ISO)
cerebral infarction  (ISO)
Child Behavior Disorders  (ISO)
cholestasis  (ISO)
Chronic Cerebral Hypoperfusion  (ISO)
chronic kidney disease  (ISO)
chronic obstructive pulmonary disease  (ISO)
cleft lip  (ISO)
cleft palate  (ISO)
colitis  (ISO)
congenital diaphragmatic hernia  (ISO)
congestive heart failure  (ISO)
coronary artery disease  (ISO)
coronary artery vasospasm  (ISO)
cystic fibrosis  (ISO)
diabetic angiopathy  (ISO)
Diabetic Cardiomyopathies  (ISO)
Diabetic Gastroparesis  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
Diaphragmatic Hernia  (ISO)
disease of cellular proliferation  (ISO)
Drug-Induced Enteropathy  (ISO)
end stage renal disease  (ISO)
endometrial carcinoma  (ISO)
Endotoxemia  (ISO)
Esophageal Neoplasms  (ISO)
esophagus adenocarcinoma  (ISO)
essential hypertension  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
extrahepatic cholestasis  (ISO)
familial hyperlipidemia  (ISO)
Fetal Growth Retardation  (ISO)
gastric ulcer  (ISO)
Graft Occlusion, Vascular  (ISO)
Hemorrhagic Shock  (ISO)
Hepatic Insufficiency  (ISO)
Hepatomegaly  (ISO)
hepatopulmonary syndrome  (ISO)
high grade glioma  (ISO)
Huntington's disease  (ISO)
Hyperemia  (ISO)
hyperglycemia  (ISO)
hyperinsulinism  (ISO)
Hyperoxia  (ISO)
hypertension  (ISO)
Hypertension Resistant to Conventional Therapy  (ISO)
Hypertriglyceridemia  (ISO)
hypothyroidism  (ISO)
Hypoxia  (ISO)
impotence  (ISO)
Insulin Resistance  (ISO)
intestinal perforation  (ISO)
Intestinal Reperfusion Injury  (ISO)
Intimal Hyperplasia  (ISO)
intracranial aneurysm  (ISO)
Intracranial Hemorrhages  (ISO)
irritable bowel syndrome  (ISO)
ischemia  (ISO)
Kidney Reperfusion Injury  (ISO)
Kuhnt-Junius degeneration  (ISO)
Left Ventricular Hypertrophy  (ISO)
leiomyoma  (ISO)
Limb Ischemia  (ISO)
liver cirrhosis  (ISO)
Liver Reperfusion Injury  (ISO)
long QT syndrome  (ISO)
lung disease  (ISO)
Lung Reperfusion Injury  (ISO)
lymphangioleiomyomatosis  (ISO)
Lymphatic Metastasis  (ISO)
macular retinal edema  (ISO)
male infertility  (ISO)
Metabolic Syndrome  (ISO)
migraine  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
Nasal Polyps  (ISO)
Neoplasm Metastasis  (ISO)
nephritis  (ISO)
obesity  (ISO)
obstructive sleep apnea  (ISO)
oligospermia  (ISO)
ovarian cancer  (ISO)
overnutrition  (ISO)
Pain  (ISO)
Perennial Allergic Rhinitis  (ISO)
perinatal necrotizing enterocolitis  (ISO)
Phyllodes Tumor  (ISO)
placental abruption  (ISO)
polycystic kidney disease  (ISO)
portal hypertension  (ISO)
pre-eclampsia  (ISO)
Preeclampsia/Eclampsia 1  (ISO)
Pregnancy-Induced Hypertension  (ISO)
primary biliary cholangitis  (ISO)
primary open angle glaucoma  (ISO)
primary ovarian insufficiency  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary edema  (ISO)
pulmonary embolism  (ISO)
pulmonary emphysema  (ISO)
pulmonary eosinophilia  (ISO)
pulmonary hypertension  (ISO)
Pulmonary Hypertension, Hypoxia-Induced  (ISO)
Radiation Pneumonitis  (ISO)
renal hypertension  (ISO)
renovascular hypertension  (ISO)
Reperfusion Injury  (ISO)
respiratory allergy  (ISO)
Retina Reperfusion Injury  (ISO)
retinal degeneration  (ISO)
retinopathy of prematurity  (ISO)
Right Ventricular Hypertrophy  (ISO)
Sepsis  (ISO)
sickle cell anemia  (ISO)
Spinal Cord Compression  (ISO)
Spinal Cord Injuries  (ISO)
Stomach Neoplasms  (ISO)
Stroke  (ISO)
Subarachnoid Hemorrhage  (ISO)
Sudden Hearing Loss  (ISO)
telangiectasis  (ISO)
Teratozoospermia  (ISO)
Testis Reperfusion Injury  (ISO)
Thromboembolism  (ISO)
Thrombotic Microangiopathies  (ISO)
transient cerebral ischemia  (ISO)
Transplant Rejection  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
uremia  (ISO)
ureteral obstruction  (ISO)
urinary bladder cancer  (ISO)
vasculitis  (ISO)
Vaso-occlusive Crisis  (ISO)
Venous Thrombosis  (ISO)
Ventricular Dysfunction, Right  (ISO)
Ventricular Premature Complexes  (ISO)
Ventricular Tachycardia  (ISO)
vestibular disease  (ISO)
vulva cancer  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
angiogenesis  (IEA,ISO)
aortic valve morphogenesis  (IEA)
arginine catabolic process  (IBA,IEA)
blood vessel diameter maintenance  (IEA)
blood vessel remodeling  (IEA)
bone development  (ISO)
cellular response to cAMP  (ISO)
cellular response to growth factor stimulus  (ISO)
cellular response to heat  (ISO)
cellular response to high density lipoprotein particle stimulus  (ISO)
cellular response to insulin stimulus  (ISO)
cellular response to low-density lipoprotein particle stimulus  (ISO)
cellular response to magnesium ion  (ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to rotenone  (ISO)
cellular response to transforming growth factor beta stimulus  (ISO)
cellular response to tumor necrosis factor  (ISO)
endocardial cushion morphogenesis  (IEA)
endothelial cell migration  (IEA)
female pregnancy  (ISO)
homeostasis of number of cells within a tissue  (IEA)
in utero embryonic development  (IEA,ISO)
lipopolysaccharide-mediated signaling pathway  (IEA,ISO)
lung development  (IEA,ISO)
negative regulation of biomineral tissue development  (IEA)
negative regulation of blood pressure  (IBA)
negative regulation of calcium ion transport  (IEA,ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of hydrolase activity  (IEA,ISO)
negative regulation of muscle hyperplasia  (IEA)
negative regulation of potassium ion transport  (IEA,ISO)
negative regulation of smooth muscle cell proliferation  (IEA,ISO)
nitric oxide biosynthetic process  (IBA,IEA,ISO)
nitric oxide mediated signal transduction  (IBA)
ovulation from ovarian follicle  (IEA,ISO)
positive regulation of angiogenesis  (IEA)
positive regulation of apoptotic process  (ISO)
positive regulation of blood vessel endothelial cell migration  (IEA)
positive regulation of gene expression  (IEA,ISO)
positive regulation of guanylate cyclase activity  (IBA,IEA)
pulmonary valve morphogenesis  (IEA)
regulation of nervous system process  (IEA)
regulation of sodium ion transport  (IEA,ISO)
regulation of systemic arterial blood pressure by endothelin  (IEA)
regulation of the force of heart contraction by chemical signal  (IEA,ISO)
removal of superoxide radicals  (IEA)
response to activity  (ISO)
response to amino acid  (ISO)
response to axon injury  (ISO)
response to candesartan  (ISO)
response to carbohydrate  (ISO)
response to corticosterone  (ISO)
response to cytokine  (ISO)
response to erythropoietin  (ISO)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to fluid shear stress  (IEA)
response to fructose  (ISO)
response to hormone  (IBA)
response to hyperoxia  (ISO)
response to hypoxia  (ISO)
response to ketone  (ISO)
response to L-arginine  (ISO)
response to lead ion  (ISO)
response to lipopolysaccharide  (IBA,ISO)
response to magnetism  (ISO)
response to mechanical stimulus  (ISO)
response to mercury ion  (ISO)
response to metal ion  (ISO)
response to metformin  (ISO)
response to nicotine  (ISO)
response to nutrient levels  (ISO)
response to organic cyclic compound  (ISO)
response to peptide  (ISO)
response to peptide hormone  (ISO)
response to salt  (ISO)
response to ultrasound  (ISO)
response to xenobiotic stimulus  (ISO)
retina development in camera-type eye  (ISO)
signal transduction  (ISO)
smooth muscle hyperplasia  (IEA)
vasodilation  (IMP)
ventricular septum morphogenesis  (IEA)

Cellular Component
apical part of cell  (ISO)
caveola  (IEA,ISO)
cytoplasm  (ISO)
cytoskeleton  (IEA)
cytosol  (IBA,ISO)
Golgi apparatus  (IEA,ISO)
membrane raft  (ISO)
mitochondrion  (ISO)
nucleolus  (ISO)
nucleus  (IBA,IEA)
plasma membrane  (IBA,ISO)
sarcolemma  (ISO)
vesicle membrane  (IBA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:9149402   PMID:14681463   PMID:14729513   PMID:15191891   PMID:15333638   PMID:15905730   PMID:15967841   PMID:16284184   PMID:17337508   PMID:17437130   PMID:17588585   PMID:17822962  
PMID:17852356   PMID:17942849   PMID:18165177   PMID:18194184   PMID:18568942   PMID:18807216   PMID:18992077   PMID:19022311   PMID:19176602   PMID:19432590   PMID:19519369   PMID:19795322  
PMID:20128797   PMID:20363881   PMID:20381143   PMID:20386492   PMID:20693398   PMID:20926145   PMID:21844953   PMID:21970701   PMID:24141169   PMID:25380860   PMID:30439484  


Genomics

Comparative Map Data
NOS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl186,209,156 - 6,228,938 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1186,209,218 - 6,228,912 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,579,253 - 6,602,572 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NOS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7150,991,017 - 151,014,588 (+)EnsemblGRCh38hg38GRCh38
GRCh387150,991,017 - 151,014,588 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377150,688,105 - 150,711,676 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367150,319,080 - 150,342,609 (+)NCBINCBI36hg18NCBI36
Build 347150,125,794 - 150,149,323NCBI
Celera7145,245,139 - 145,269,020 (+)NCBI
Cytogenetic Map7q36.1NCBI
HuRef7144,500,690 - 144,524,025 (+)NCBIHuRef
CHM1_17150,696,541 - 150,720,093 (+)NCBICHM1_1
CRA_TCAGchr7v27150,017,398 - 150,041,276 (+)NCBI
Nos3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39524,569,772 - 24,589,472 (+)NCBIGRCm39mm39
GRCm39 Ensembl524,569,808 - 24,589,472 (+)Ensembl
GRCm38524,364,816 - 24,384,474 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl524,364,810 - 24,384,474 (+)EnsemblGRCm38mm10GRCm38
MGSCv37523,870,637 - 23,890,292 (+)NCBIGRCm37mm9NCBIm37
MGSCv36523,874,884 - 23,894,536 (+)NCBImm8
Celera521,311,457 - 21,334,226 (+)NCBICelera
Cytogenetic Map5A3NCBI
cM Map511.32NCBI
Nos3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2410,793,834 - 10,814,170 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl410,793,834 - 10,814,166 (-)Ensembl
Rnor_6.047,321,908 - 7,342,404 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl47,320,668 - 7,342,410 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.047,333,272 - 7,353,767 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.446,158,847 - 6,179,441 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.146,158,846 - 6,179,441 (-)NCBI
Celera46,408,408 - 6,428,650 (-)NCBICelera
Cytogenetic Map4q11NCBI
Nos3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554915,438,010 - 5,460,814 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554915,438,228 - 5,457,308 (+)NCBIChiLan1.0ChiLan1.0
NOS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17154,730,009 - 154,755,233 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7154,730,009 - 154,755,233 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07142,577,334 - 142,600,702 (+)NCBIMhudiblu_PPA_v0panPan3
NOS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11615,054,196 - 15,072,454 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1615,011,344 - 15,072,277 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1615,662,484 - 15,680,572 (+)NCBI
ROS_Cfam_1.01616,776,276 - 16,794,533 (+)NCBI
UMICH_Zoey_3.11615,148,899 - 15,166,990 (+)NCBI
UNSW_CanFamBas_1.01615,730,292 - 15,748,445 (+)NCBI
UU_Cfam_GSD_1.01615,781,028 - 15,799,144 (+)NCBI
Nos3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051186,457,663 - 6,476,277 (-)NCBI
SpeTri2.0NW_0049365276,427,147 - 6,445,770 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NOS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121119,174,829 - 119,196,840 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607215,144,615 - 15,167,202 (+)NCBIVero_WHO_p1.0
Nos3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248005,600,215 - 5,619,020 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 1 4 3 5 2 23 1 2 1
Below cutoff 9 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000017913   ⟹   ENSSSCP00000017432
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl186,209,156 - 6,228,206 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000050205   ⟹   ENSSSCP00000048632
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl186,209,156 - 6,227,467 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000076886   ⟹   ENSSSCP00000065613
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl186,209,162 - 6,228,938 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000077658   ⟹   ENSSSCP00000072233
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl186,209,156 - 6,227,865 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000078347   ⟹   ENSSSCP00000067104
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl186,209,162 - 6,227,467 (-)Ensembl
RefSeq Acc Id: NM_214295   ⟹   NP_999460
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1186,209,218 - 6,228,912 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_999460   ⟸   NM_214295
- UniProtKB: Q28969 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000067104   ⟸   ENSSSCT00000078347
RefSeq Acc Id: ENSSSCP00000048632   ⟸   ENSSSCT00000050205
RefSeq Acc Id: ENSSSCP00000017432   ⟸   ENSSSCT00000017913
RefSeq Acc Id: ENSSSCP00000065613   ⟸   ENSSSCT00000076886
RefSeq Acc Id: ENSSSCP00000072233   ⟸   ENSSSCT00000077658
Protein Domains
FAD-binding FR-type   Flavodoxin-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016450 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000017432 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000048632 UniProtKB/TrEMBL
  ENSSSCP00000065613 UniProtKB/TrEMBL
  ENSSSCP00000067104 UniProtKB/TrEMBL
  ENSSSCP00000072233 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017913 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000050205 UniProtKB/TrEMBL
  ENSSSCT00000076886 UniProtKB/TrEMBL
  ENSSSCT00000077658 UniProtKB/TrEMBL
  ENSSSCT00000078347 UniProtKB/TrEMBL
Gene3D-CATH 1.20.990.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.360 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CysJ-like_FAD-binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAD-bd_FR_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavdoxin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavodoxin/NO_synth UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavoprot_Pyr_Nucl_cyt_Rdtase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavoprotein-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FNR_nucleotide-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NADPH_Cyt_P450_Rdtase_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NOS_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NOS_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NOS_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OxRdtase_FAD/NAD-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Riboflavin_synthase-like_b-brl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397557 UniProtKB/Swiss-Prot
NCBI Gene NOS3 ENTREZGENE
Pfam FAD_binding_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavodoxin_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD_binding_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NO_synthase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF NOS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS FLAVODOXIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FPNCR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FAD_FR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FLAVODOXIN_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NOS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52218 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52343 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56512 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF63380 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A287AXM6_PIG UniProtKB/TrEMBL
  A0A480KWC4_PIG UniProtKB/TrEMBL
  A0A5G2QQU3_PIG UniProtKB/TrEMBL
  A0A5G2R4U2_PIG UniProtKB/TrEMBL
  A0A5K1UKC0_PIG UniProtKB/TrEMBL
  NOS3_PIG UniProtKB/Swiss-Prot, ENTREZGENE