CYCS (cytochrome c, somatic) - Rat Genome Database
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Gene: CYCS (cytochrome c, somatic) Sus scrofa
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Symbol: CYCS
Name: cytochrome c, somatic
RGD ID: 14251226
Description: ENCODES a protein that exhibits enzyme binding (ortholog); heme binding (ortholog); INVOLVED IN activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (ortholog); apoptotic process (ortholog); glial cell apoptotic process (ortholog); PARTICIPATES IN cardiolipin metabolic pathway; ceramide signaling pathway; electron transport chain pathway; ASSOCIATED WITH brain ischemia (ortholog); Chloracne (ortholog); cholangiocarcinoma (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrial intermembrane space (ortholog); INTERACTS WITH 3-methyladenine; ATP; bezafibrate
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CYC; cytochrome c
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1847,169,866 - 47,173,866 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11847,169,921 - 47,172,212 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21852,036,068 - 52,038,366 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:5855656   PMID:14681463   PMID:15679890   PMID:17145712   PMID:17934797   PMID:21880174  


Genomics

Comparative Map Data
CYCS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1847,169,866 - 47,173,866 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11847,169,921 - 47,172,212 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21852,036,068 - 52,038,366 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CYCS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl725,120,091 - 25,125,361 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl725,118,656 - 25,125,260 (-)EnsemblGRCh38hg38GRCh38
GRCh38725,118,656 - 25,125,260 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37725,158,270 - 25,164,980 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh37725,158,275 - 25,164,879 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36725,124,800 - 25,131,480 (-)NCBINCBI36hg18NCBI36
Celera725,146,921 - 25,154,374 (-)NCBI
Cytogenetic Map7p15.3NCBI
HuRef725,044,828 - 25,051,539 (-)NCBIHuRef
CHM1_1725,160,181 - 25,166,894 (-)NCBICHM1_1
CRA_TCAGchr7v2725,209,510 - 25,216,457 (-)NCBI
Cycs
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39650,539,543 - 50,543,549 (-)NCBIGRCm39mm39
GRCm38650,562,563 - 50,566,569 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl650,562,563 - 50,566,538 (-)EnsemblGRCm38mm10GRCm38
MGSCv37650,512,562 - 50,516,473 (-)NCBIGRCm37mm9NCBIm37
MGSCv36650,492,149 - 50,496,060 (-)NCBImm8
Celera651,079,647 - 51,083,558 (-)NCBICelera
Cytogenetic Map6B2.3NCBI
cM Map624.32NCBI
Cycs
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2479,651,894 - 79,653,994 (-)NCBI
Rnor_6.0 Ensembl480,331,227 - 80,333,326 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0480,331,226 - 80,333,326 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04145,002,156 - 145,004,256 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4478,825,878 - 78,827,978 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1479,102,008 - 79,104,108 (-)NCBI
Celera474,558,589 - 74,560,689 (-)NCBICelera
Cytogenetic Map4q24NCBI
LOC102023786
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541027,086,405 - 27,089,255 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541027,086,405 - 27,089,255 (-)NCBIChiLan1.0ChiLan1.0
LOC100986481
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1725,396,013 - 25,398,549 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl725,396,013 - 25,398,549 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0725,784,900 - 25,791,598 (-)NCBIMhudiblu_PPA_v0panPan3
CYCS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1438,579,446 - 38,581,983 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11438,579,446 - 38,581,983 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
LOC103226354
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12133,251,825 - 33,253,298 (+)NCBI
LOC101718508
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247395,411,192 - 5,413,995 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 4 3 5 2 23 2 3 3
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000018195   ⟹   ENSSSCP00000017704
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1847,169,866 - 47,173,866 (+)Ensembl
RefSeq Acc Id: NM_001129970   ⟹   NP_001123442
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11847,169,921 - 47,172,212 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001123442 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAX77008 (Get FASTA)   NCBI Sequence Viewer  
  P62895 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001123442   ⟸   NM_001129970
- UniProtKB: P62895 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000017704   ⟸   ENSSSCT00000018195


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016714 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSSSCG00005038422 UniProtKB/Swiss-Prot
  ENSSSCG00015058229 UniProtKB/Swiss-Prot
  ENSSSCG00025012632 UniProtKB/Swiss-Prot
  ENSSSCG00030002705 UniProtKB/Swiss-Prot
  ENSSSCG00035073660 UniProtKB/Swiss-Prot
  ENSSSCG00040008367 UniProtKB/Swiss-Prot
  ENSSSCG00045017039 UniProtKB/Swiss-Prot
  ENSSSCG00050048183 UniProtKB/Swiss-Prot
  ENSSSCG00055002302 UniProtKB/Swiss-Prot
  ENSSSCG00060034366 UniProtKB/Swiss-Prot
  ENSSSCG00065035264 UniProtKB/Swiss-Prot
  ENSSSCG00070014000 UniProtKB/Swiss-Prot
Ensembl Protein ENSSSCP00000017704 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSSSCP00005037986 UniProtKB/Swiss-Prot
  ENSSSCP00005037996 UniProtKB/Swiss-Prot
  ENSSSCP00005038000 UniProtKB/Swiss-Prot
  ENSSSCP00015031338 UniProtKB/Swiss-Prot
  ENSSSCP00025006661 UniProtKB/Swiss-Prot
  ENSSSCP00030001365 UniProtKB/Swiss-Prot
  ENSSSCP00035042328 UniProtKB/Swiss-Prot
  ENSSSCP00040004216 UniProtKB/Swiss-Prot
  ENSSSCP00045020076 UniProtKB/Swiss-Prot
  ENSSSCP00050028275 UniProtKB/Swiss-Prot
  ENSSSCP00055003333 UniProtKB/Swiss-Prot
  ENSSSCP00060019964 UniProtKB/Swiss-Prot
  ENSSSCP00065020701 UniProtKB/Swiss-Prot
  ENSSSCP00070022790 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000018195 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSSSCT00005061435 UniProtKB/Swiss-Prot
  ENSSSCT00005061457 UniProtKB/Swiss-Prot
  ENSSSCT00005061462 UniProtKB/Swiss-Prot
  ENSSSCT00015077795 UniProtKB/Swiss-Prot
  ENSSSCT00025016702 UniProtKB/Swiss-Prot
  ENSSSCT00030003474 UniProtKB/Swiss-Prot
  ENSSSCT00035099861 UniProtKB/Swiss-Prot
  ENSSSCT00040010932 UniProtKB/Swiss-Prot
  ENSSSCT00045028997 UniProtKB/Swiss-Prot
  ENSSSCT00050065643 UniProtKB/Swiss-Prot
  ENSSSCT00055004346 UniProtKB/Swiss-Prot
  ENSSSCT00060046609 UniProtKB/Swiss-Prot
  ENSSSCT00065048025 UniProtKB/Swiss-Prot
  ENSSSCT00070027397 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.760.10 UniProtKB/Swiss-Prot
InterPro Cyt_c-like_dom UniProtKB/Swiss-Prot
  Cyt_c-like_dom_sf UniProtKB/Swiss-Prot
  Cyt_c_1A/1B UniProtKB/Swiss-Prot
KEGG Report ssc:100170131 UniProtKB/Swiss-Prot
NCBI Gene CYCS ENTREZGENE
PANTHER PTHR11961 UniProtKB/Swiss-Prot
Pfam Cytochrom_C UniProtKB/Swiss-Prot
PRINTS CYTCHRMECIAB UniProtKB/Swiss-Prot
PROSITE CYTC UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46626 UniProtKB/Swiss-Prot
UniProt CYC_PIG UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P00006 UniProtKB/Swiss-Prot
  Q56P24 UniProtKB/Swiss-Prot