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Gene: FOXC2 (forkhead box C2) Sus scrofa

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Symbol:

FOXC2

Name:

forkhead box C2

RGD ID:

13929356

Description:

ENCODES a protein that exhibits DNA binding (ortholog); INVOLVED IN apoptotic process involved in outflow tract morphogenesis (inferred); artery morphogenesis (inferred); blood vessel development (inferred); ASSOCIATED WITH Cardiovascular Abnormalities (ortholog); congenital diaphragmatic hernia (ortholog); congestive heart failure (ortholog); FOUND IN nuclear body (inferred); nucleoplasm (inferred); nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

forkhead box C2 (MFH-1, mesenchyme forkhead 1); forkhead box protein C2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FOXC2 (forkhead box C2)	HGNC	Ensembl, NCBI, OrthoDB
Mus musculus (house mouse):	Foxc2 (forkhead box C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Foxc2 (forkhead box C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FOXC2 (forkhead box C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FOXC2 (forkhead box C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Foxc2 (forkhead box C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FOXC2 (forkhead box C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Foxc2 (forkhead box C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	2,552,862 - 2,554,367 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	2,552,141 - 2,555,041 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	2,756,138 - 2,761,356 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
FOXC2	Pig	congestive heart failure		ISO	FOXC2 (Homo sapiens)	9068941		RGD	PMID:16952980 and REF_RGD_ID:1582564
FOXC2	Pig	eyelid disease		ISO	FOXC2 (Homo sapiens)	9068941	lymphedema-distichiasis syndrome more ...	RGD	PMID:15523639 and REF_RGD_ID:1601217
FOXC2	Pig	Insulin Resistance		ISO	FOXC2 (Homo sapiens)	9068941	DNA:polymorphism:5'ut:-512C>T	RGD	PMID:12453913 and REF_RGD_ID:1601219
FOXC2	Pig	lymphedema		ISO	FOXC2 (Homo sapiens)	9068941	lymphedema and ptosis more ...	RGD	PMID:11371511 and REF_RGD_ID:1601216
FOXC2	Pig	lymphedema		ISO	FOXC2 (Homo sapiens)	9068941	lymphedema-distichiasis syndrome more ...	RGD	PMID:15523639 and REF_RGD_ID:1601217
FOXC2	Pig	nephritis		ISO	FOXC2 (Homo sapiens)	9068941	DNA:insertion:1006insA	RGD	PMID:15523639 and REF_RGD_ID:1601217
FOXC2	Pig	obesity		ISO	FOXC2 (Homo sapiens)	9068941	DNA:polymorphism:5'ut:-512C>T(human)	RGD	PMID:15601967 and REF_RGD_ID:1601218
FOXC2	Pig	ptosis		ISO	FOXC2 (Homo sapiens)	9068941	lymphedema and ptosis more ...	RGD	PMID:11371511 and REF_RGD_ID:1601216
FOXC2	Pig	type 2 diabetes mellitus	no_association	ISO	FOXC2 (Homo sapiens)	9068941	DNA:polymorphism:5'ut:-512C>T more ...	RGD	PMID:12540636 and REF_RGD_ID:1601220
FOXC2	Pig	type 2 diabetes mellitus		ISO	FOXC2 (Homo sapiens)	9068941	DNA:insertion:1006insA	RGD	PMID:15523639 and REF_RGD_ID:1601217

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
FOXC2	Pig	genetic disease		ISO	FOXC2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:12114478 more ...
FOXC2	Pig	Hydrops Fetalis		ISO	FOXC2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Non-immune hydrops fetalis	ClinVar	PMID:25741868
FOXC2	Pig	immunodeficiency 32B		ISO	FOXC2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Immunodeficiency 32B	ClinVar	PMID:28492532
FOXC2	Pig	lymphedema-distichiasis syndrome		ISO	FOXC2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10417285 more ...
FOXC2	Pig	Lymphedema-Distichiasis Syndrome with Renal Disease and Diabetes Mellitus		ISO	FOXC2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Lymphedema-distichiasis syndrome with renal disease and diabetes mellitus	ClinVar	PMID:15523639
FOXC2	Pig	persistent fetal circulation syndrome		ISO	FOXC2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia	ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
FOXC2	Pig	Cardiovascular Abnormalities		ISO	FOXC2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:9409679
FOXC2	Pig	congenital diaphragmatic hernia		ISO	FOXC2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:27663689
FOXC2	Pig	Craniofacial Abnormalities		ISO	FOXC2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:9106663 and PMID:9409679
FOXC2	Pig	Musculoskeletal Abnormalities		ISO	FOXC2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:9106663
FOXC2	Pig	tetralogy of Fallot		ISO	FOXC2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:25093829

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
FOXC2	Pig	lymphedema-distichiasis syndrome		ISO	FOXC2 (Homo sapiens)	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
FOXC2	Pig	anatomical structure morphogenesis	involved_in	IBA	FB:FBgn0000659 more ...	150520179		GO_Central	GO_REF:0000033
FOXC2	Pig	apoptotic process involved in outflow tract morphogenesis	acts_upstream_of	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	artery morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	blood vessel development	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	blood vessel diameter maintenance	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	blood vessel remodeling	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	branching involved in blood vessel morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	camera-type eye development	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	cardiac muscle cell proliferation	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	cell differentiation	involved_in	IBA	FB:FBgn0000659 more ...	150520179		GO_Central	GO_REF:0000033
FOXC2	Pig	cell population proliferation	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	collagen fibril organization	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	embryonic cranial skeleton morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	embryonic heart tube development	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	embryonic skeletal system morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	embryonic viscerocranium morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	glomerular endothelium development	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	glomerular mesangial cell development	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	heart development	involved_in	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	heart development	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	heart morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	insulin receptor signaling pathway	involved_in	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	kidney development	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	lymph vessel development	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	lymphangiogenesis	involved_in	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	metanephros development	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	negative regulation of apoptotic process involved in outflow tract morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	negative regulation of cold-induced thermogenesis	involved_in	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	negative regulation of transcription by RNA polymerase II	involved_in	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	neural crest cell development	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	Notch signaling pathway	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	ossification	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	paraxial mesoderm formation	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	paraxial mesodermal cell fate commitment	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	podocyte differentiation	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	positive regulation of cell adhesion mediated by integrin	involved_in	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	positive regulation of cell migration involved in sprouting angiogenesis	involved_in	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	positive regulation of DNA-templated transcription	involved_in	IEA	UniProtKB:Q61850 more ...	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	positive regulation of endothelial cell migration	involved_in	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	positive regulation of transcription by RNA polymerase II	involved_in	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	positive regulation of transcription by RNA polymerase II	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	positive regulation of vascular wound healing	involved_in	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	regulation of DNA-templated transcription	involved_in	IEA	InterPro:IPR001766 more ...	150520179		InterPro	GO_REF:0000002
FOXC2	Pig	regulation of organ growth	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	regulation of transcription by RNA polymerase II	involved_in	IBA	FB:FBgn0000659 more ...	150520179		GO_Central	GO_REF:0000033
FOXC2	Pig	response to hormone	involved_in	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	skeletal system development	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	somitogenesis	involved_in	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	ureteric bud development	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	vascular endothelial growth factor receptor signaling pathway	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	ventricular cardiac muscle tissue morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
FOXC2	Pig	nuclear body	located_in	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	nucleoplasm	located_in	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	150520179		UniProt	GO_REF:0000044
FOXC2	Pig	nucleus	located_in	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	nucleus	located_in	IEA	UniRule:UR000413741	150520179		UniProt	GO_REF:0000104
FOXC2	Pig	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	150520179		UniProt	GO_REF:0000043

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
FOXC2	Pig	chromatin DNA binding	enables	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	DNA binding		ISO	Foxc2 (Rattus norvegicus)	9068941		RGD	PMID:7683413 and REF_RGD_ID:632667
FOXC2	Pig	DNA binding	enables	IEA	UniProtKB-KW:KW-0238	150520179		UniProt	GO_REF:0000043
FOXC2	Pig	DNA binding	enables	IEA	UniRule:UR000413741	150520179		UniProt	GO_REF:0000104
FOXC2	Pig	DNA binding	enables	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	DNA-binding transcription activator activity	enables	IEA	UniProtKB:Q61850 more ...	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	DNA-binding transcription activator activity, RNA polymerase II-specific	enables	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	DNA-binding transcription factor activity	enables	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	DNA-binding transcription factor activity	enables	IEA	InterPro:IPR001766 more ...	150520179		InterPro	GO_REF:0000002
FOXC2	Pig	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IBA	FB:FBgn0000659 more ...	150520179		GO_Central	GO_REF:0000033
FOXC2	Pig	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	identical protein binding	enables	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	promoter-specific chromatin binding	enables	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	protein binding	enables	ISO	UniProtKB:Q08379 more ...	9068941	PMID:32296183	IntAct	PMID:32296183
FOXC2	Pig	protein binding	enables	ISO	UniProtKB:P14373 more ...	9068941	PMID:25416956	IntAct	PMID:25416956
FOXC2	Pig	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	IBA	MGI:1096329 more ...	150520179		GO_Central	GO_REF:0000033
FOXC2	Pig	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	RNA polymerase II transcription regulatory region sequence-specific DNA binding	enables	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	sequence-specific DNA binding	enables	IEA	InterPro:IPR001766 more ...	150520179		InterPro	GO_REF:0000002
FOXC2	Pig	sequence-specific DNA binding	enables	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	sequence-specific double-stranded DNA binding	enables	IEA	UniProtKB:Q99958 and ensembl:ENSP00000497759	150520179		Ensembl	GO_REF:0000107
FOXC2	Pig	transcription cis-regulatory region binding	enables	IEA	UniProtKB:Q61850 and ensembl:ENSMUSP00000055290	150520179		Ensembl	GO_REF:0000107

PMID:30032202

FOXC2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	2,552,862 - 2,554,367 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	2,552,141 - 2,555,041 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	2,756,138 - 2,761,356 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FOXC2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	86,566,829 - 86,569,728 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	86,566,829 - 86,569,728 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	86,600,435 - 86,603,334 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	85,158,443 - 85,159,948 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	85,158,442 - 85,159,948	NCBI
Celera	16	70,901,820 - 70,903,503 (+)	NCBI		Celera
Cytogenetic Map	16	q24.1	NCBI
HuRef	16	72,340,749 - 72,342,345 (+)	NCBI		HuRef
CHM1_1	16	88,012,585 - 88,014,267 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	92,635,146 - 92,638,044 (+)	NCBI		T2T-CHM13v2.0

Foxc2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	121,842,910 - 121,845,634 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	121,842,910 - 121,845,634 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	121,116,171 - 121,118,895 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	121,116,171 - 121,118,895 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	123,640,071 - 123,642,795 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	124,002,560 - 124,004,872 (+)	NCBI		MGSCv36	mm8
Celera	8	125,334,251 - 125,336,975 (+)	NCBI		Celera
Cytogenetic Map	8	E1	NCBI
cM Map	8	70.33	NCBI

Foxc2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	66,094,718 - 66,097,420 (+)	NCBI		GRCr8
mRatBN7.2	19	49,186,034 - 49,188,736 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	49,185,662 - 49,188,737 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	55,977,317 - 55,980,018 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	56,661,030 - 56,663,732 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	58,875,485 - 58,878,187 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	53,044,379 - 53,047,081 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	53,044,379 - 53,047,081 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	63,788,037 - 63,790,739 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.1	1	228,513,040 - 228,513,088 (-)	NCBI
Celera	19	48,432,333 - 48,435,035 (+)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

FOXC2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	96,322,973 - 96,325,904 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	102,240,170 - 102,243,107 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	67,237,476 - 67,239,545 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	86,569,509 - 86,571,878 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

FOXC2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	66,234,336 - 66,296,007 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	66,294,176 - 66,295,693 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	66,246,461 - 66,254,587 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	66,455,805 - 66,464,138 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	5	66,479,102 - 66,487,010 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	66,314,300 - 66,322,205 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	66,727,335 - 66,735,464 (-)	NCBI		UU_Cfam_GSD_1.0

Foxc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	26,482,456 - 26,485,324 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936641	2,236,873 - 2,238,375 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936641	2,236,224 - 2,238,501 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FOXC2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	71,951,980 - 71,955,021 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	71,952,632 - 71,954,134 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	3,750,917 - 3,753,843 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Foxc2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624746	2,632,619 - 2,634,085 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624746	2,632,547 - 2,634,867 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in FOXC2
73 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

circulatory system	ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system
1	4	1	1	4	3	4	2	2


RefSeq Transcripts	XM_021093694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000029063 ⟹ ENSSSCP00000042729

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	6	2,552,862 - 2,554,367 (-)	Ensembl

RefSeq Acc Id:

XM_021093694 ⟹ XP_020949353

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	6	2,552,141 - 2,555,041 (-)	NCBI

Sequence:

show sequence

CAGAAGTCTGGTTCTGCGTGGCTGGGTCTTAGAGCCGACGGATTCGGCGCTCCTCGTCCTGATTGGTGCTAAGTCCCCACAGCGGCCAGGTTATTGGTCCAAAGTTCCCGGAGGGGGCGTGGCCGCAG
GAAAGTAAAAACTCGCTTTCAGTAAGACTTTTGAAACTTTTCCCAATCCCTAAAAGGGACTTTGCCTCTTTTTCCGGGCTCGGCAGGGCAGCACTCTGGACCCCGACTCGCTGACCCTCAGCGCTACC
GATTTGCCGGGGGGCTTGGAGAGCCGCCGTCCCCTTCCCGACGCGGACCGAGGGGGCCAGCCTCGGTCCACCGCGGTGCGTGGCGACTCTGCTCCGGCCCGGCCGCCCTCCCGGGCTGCCACCAGCCA
AGTCCCGAGAGCGAGCGGGCGAGCGAACAGGGGCCGGCGCTGCGCTCTCCCGGGCGCGCCCTCCAGGATGCTGCCTCTCCCGGTCCGCTGAAAACGAGCGCCCCTTCCCGGCCCGAAGGCGGGAGCCC
AGCGCCGGCGCCTCCTCCAGCTCACTCCTGAGGCTTCCAGGCGCCCGGGCTCCCCCCGCCGGTTCCCTTCCTCCCTCTCTCCTCTCTCGCTCGCGCTCGCTCTCACAGGGCCTTCCTCACGGTCCGTG
CGCGCAGGCGGTGGCTAGCCGTCTCGGACGCAGCATGCAGGCGCGCTACTCTGTGTCCGACCCCAACGCCCTGGGAGTGGTGCCCTACTTGAGCGAGCAGAATTACTACCGCGCGGCGGGCAGCTACG
GCGGCATGGCCAGCCCCATGGGCGTCTATTCGGGCCACCCGGAGCAGTACGGCGCGGGCATGGGCCGCTCCTACGCTCCCTACCACCACCACCAGCCCGCGGCGCCCAAGGACCTCGTGAAGCCGCCC
TACAGCTACATCGCACTCATCACCATGGCGATCCAGAACGCGCCCGAGAAGAAGATCACCCTGAACGGCATCTACCAGTTCATCATGGACCGCTTCCCCTTCTACCGGGAGAACAAGCAGGGCTGGCA
GAACAGCATCCGCCACAACCTCTCGCTCAACGAGTGCTTCGTCAAGGTGCCCCGTGACGACAAGAAGCCTGGCAAGGGCAGCTACTGGACCCTGGACCCGGACTCCTACAACATGTTCGAGAACGGCA
GCTTCCTGCGGCGCCGGCGGCGCTTCAAGAAGAAGGACGTGCCCAAGGAGAAGGAGGAGCGGGCCCACCTCAAGGAGCCGCCCCCGGCGGCGTCCAAGGGAGCCCCGGCCGGGCCCCCCCTAGCGGAC
GCCCCCAAGGAGGTCGAGAAGAAGGTGGTGATCAAGAGCGAGGCGGCGTCGCCGGCGCTGCCGGTCATCACCAAGGTGGAGACGCTGAGCCCCGAAAGCGCGCTGCAGGGCAGCCCGCGCAGCGCGGC
CTCCACGCCCGCCGGCTCCCCCGACGGCTCGCTGCCGGAGCACCACGCAGGCGCGCCCAACGGGCTGCCGGGCTTCAGCGTGGAGAACATCATGACGCTGCGAACGTCGCCGCCCGGCGGCGAGCTGA
GCCCCGCGGCTGGGCGCGCGGGCCTGGTGGTGCCGCCGCTGGCGCTGCCCTACGCCGCCGCGCCGCCCGCCGCCTACGGGCAGCCCTGCGCGCAGGGCCTGGAGGCCGCGGGCGCTGGAGGCTACCAG
TGCAGCATGCGCGCCATGAGCCTGTACACCGGGACCGAGCGGCCGGCGCACATGTGCGTCCCGCCAGCGCTGGACGAGGCTCTCTCGGACCACACGAGCGGCCCCACGTCGCCCCTAAGCGCCCTCAA
CCTCGCCGCCGGCCAGGAGGGCGCGCTCGCCGCCGCCGGCCACCACCACCAGCATCACGGCCACCACCACCCGCAGGCGCCGCCGCCCCCGCCGGCTCCCCAGCCCCAGCCGGCGCCGCAGCCCGGGG
CCGCCGCGGCCCAGGCGGCCTCCTGGTATCTCAACCACAGCGGGGACCTGAACCACCTCCCCGGCCACACGTTCGCGGCCCAGCAGCAGACTTTCCCTAACGTCAGGGAGATGTTCACCTCCCACCGG
CTGGGGATTGAGAACTCGACCCTCGGGGAACCCCAAGTGAGCAGCAACGCGAGCTGTCAGCTGCCCTACAGATCCACGCCATCTCTCTACCGCCACGCGGCCCCGTATTCCTATGACTGCACGAAATA
CTGACCTGCCCCGGCCCTCCTCTGCCCCGGCCCGCTCCGGCGTCGTCTCCCAGACGCGACCCTCTCAGACAGTGCAGGCTGCAGAGACGCAGAAAGAACCAAAACATGGCCCACCGCTTTTTCGCAGA
CCCGGGAGCAGAGAGAGTGCGCGCGCCAGCCTCCGCCCTCTGCGAGCTGCAGGTAACTTTCACTCGCCGCCCCGTTTCTGAGATCCCAAGAAGCCCCGTACAGGAATGCGGCCCAACGAAATGAATAT
CGATTTTTTAAATCCCCCTCCCCTTCCAGGATGGCTATGCTAACGGCTCCACTTGGGGTTTCAAAAAGTATAACTTATGGACCAAATCCCATAGCGACCCATTAATGACTCTCTGTAGAGACCCCCAC
ACGTCTGTGGGGGTCTCTATAGATTATGTATGTGCTGTGTGTAATTTTAAATTTCTCTATCCGTGCTGTACAAATGTGTGGATTTGTAATCAGGCTATTTTTTGTTGTTGTTCAGAGCCATTAATATA
ATATTTAAAGTTGAGTTCACTGGATAATTTCTCATCTTGCCCGACCATTTCTAACTGCCAAAGAGAAAATTCAAGAAACCTTTGGGGGGGTTTTCCCCCCTGTACAATTACGATATAATTCTTTTCCC
AGTTGTAGGTCTTCTACAAAACAAGAACATAATTTATTGTTTGTTGTTGTTGGCAGATAAAGAAGTCAAGTATCTGATACTTTTT

hide sequence


Protein RefSeqs	XP_020949353	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000042729
	ENSSSCP00000042729.1
	ENSSSCP00035012894.1
	ENSSSCP00040027822.1
	ENSSSCP00045039861.1
	ENSSSCP00050027759.1
	ENSSSCP00055023685.1
	ENSSSCP00060024966.1
	ENSSSCP00070011254.1

RefSeq Acc Id:

XP_020949353 ⟸ XM_021093694

- UniProtKB:

A0A287AFQ6 (UniProtKB/TrEMBL), A0A4X1T7T4 (UniProtKB/TrEMBL), A0A8D1VH33 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQARYSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYGAGMGRSYAPYHHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNE
CFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVPKEKEERAHLKEPPPAASKGAPAGPPLADAPKEVEKKVVIKSEAASPALPVITKVETLSPESALQGSPRSAASTPAGSPDGSL
PEHHAGAPNGLPGFSVENIMTLRTSPPGGELSPAAGRAGLVVPPLALPYAAAPPAAYGQPCAQGLEAAGAGGYQCSMRAMSLYTGTERPAHMCVPPALDEALSDHTSGPTSPLSALNLAAGQEGALAA
AGHHHQHHGHHHPQAPPPPPAPQPQPAPQPGAAAAQAASWYLNHSGDLNHLPGHTFAAQQQTFPNVREMFTSHRLGIENSTLGEPQVSSNASCQLPYRSTPSLYRHAAPYSYDCTKY

hide sequence

Ensembl Acc Id:

ENSSSCP00000042729 ⟸ ENSSSCT00000029063

Protein Domains

Fork-head

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000029296	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00035024900	UniProtKB/TrEMBL
	ENSSSCG00040048754	UniProtKB/TrEMBL
	ENSSSCG00045033388	UniProtKB/TrEMBL
	ENSSSCG00050047280	UniProtKB/TrEMBL
	ENSSSCG00055015103	UniProtKB/TrEMBL
	ENSSSCG00060043019	UniProtKB/TrEMBL
	ENSSSCG00070007101	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000029063	ENTREZGENE
	ENSSSCT00000029063.2	UniProtKB/TrEMBL
	ENSSSCT00035032740.1	UniProtKB/TrEMBL
	ENSSSCT00040065691.1	UniProtKB/TrEMBL
	ENSSSCT00045057049.1	UniProtKB/TrEMBL
	ENSSSCT00050064414.1	UniProtKB/TrEMBL
	ENSSSCT00055029755.1	UniProtKB/TrEMBL
	ENSSSCT00060058329.1	UniProtKB/TrEMBL
	ENSSSCT00070013649.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
InterPro	Fork_head_dom	UniProtKB/TrEMBL
	FOX_domain-containing	UniProtKB/TrEMBL
	FOXC1/C2-like_FH	UniProtKB/TrEMBL
	TF_fork_head_CS_1	UniProtKB/TrEMBL
	TF_fork_head_CS_2	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	FOXC2	ENTREZGENE
PANTHER	FORKHEAD BOX PROTEIN	UniProtKB/TrEMBL
	FORKHEAD BOX PROTEIN C2	UniProtKB/TrEMBL
Pfam	Forkhead	UniProtKB/TrEMBL
PRINTS	FORKHEAD	UniProtKB/TrEMBL
PROSITE	FORK_HEAD_1	UniProtKB/TrEMBL
	FORK_HEAD_2	UniProtKB/TrEMBL
	FORK_HEAD_3	UniProtKB/TrEMBL
SMART	SM00339	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46785	UniProtKB/TrEMBL
UniProt	A0A287AFQ6	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1T7T4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1VH33	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:88198	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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