ADRB3 (adrenoceptor beta 3) - Rat Genome Database

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Gene: ADRB3 (adrenoceptor beta 3) Sus scrofa
Analyze
Symbol: ADRB3
Name: adrenoceptor beta 3
RGD ID: 14253523
Description: ENCODES a protein that exhibits beta-adrenergic receptor activity (ortholog); epinephrine binding (ortholog); norepinephrine binding (ortholog); INVOLVED IN activation of adenylate cyclase activity (ortholog); adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); aging (ortholog); PARTICIPATES IN G protein mediated signaling pathway via Galphas family; ASSOCIATED WITH Alzheimer's disease (ortholog); colitis (ortholog); congestive heart failure (ortholog); FOUND IN membrane (ortholog); nucleus (ortholog); receptor complex (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adrenergic, beta-3-, receptor; BAR3; beta 3 adrenergic receptor; beta-3 adrenergic receptor; beta-3 adrenoceptor; beta-3 adrenoreceptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11548,468,803 - 48,478,370 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21555,481,787 - 55,489,921 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:7592080   PMID:10229356   PMID:20151470   PMID:20163650   PMID:24144049   PMID:24951958  


Genomics

Comparative Map Data
ADRB3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11548,468,803 - 48,478,370 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21555,481,787 - 55,489,921 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADRB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl837,962,990 - 37,966,599 (-)EnsemblGRCh38hg38GRCh38
GRCh38837,962,990 - 37,966,599 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37837,820,508 - 37,824,117 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36837,939,673 - 37,943,341 (-)NCBINCBI36hg18NCBI36
Build 34837,939,672 - 37,943,341NCBI
Celera836,772,222 - 36,775,893 (-)NCBI
Cytogenetic Map8p11.23NCBI
HuRef836,354,913 - 36,358,584 (-)NCBIHuRef
CHM1_1838,021,981 - 38,025,652 (-)NCBICHM1_1
Adrb3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39827,715,804 - 27,720,833 (-)NCBIGRCm39mm39
GRCm39 Ensembl827,715,804 - 27,740,644 (-)Ensembl
GRCm38827,225,776 - 27,230,845 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl827,225,776 - 27,250,616 (-)EnsemblGRCm38mm10GRCm38
MGSCv37828,336,248 - 28,340,060 (-)NCBIGRCm37mm9NCBIm37
MGSCv36828,691,712 - 28,695,524 (-)NCBImm8
Celera828,716,093 - 28,719,905 (-)NCBICelera
Cytogenetic Map8A2NCBI
cM Map815.94NCBI
Adrb3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21664,839,820 - 64,844,552 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1664,841,788 - 64,844,552 (+)Ensembl
Rnor_6.01669,003,541 - 69,006,632 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1669,003,868 - 69,006,632 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01668,673,983 - 68,676,747 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41669,163,620 - 69,166,384 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11669,163,825 - 69,166,590 (+)NCBI
Celera1662,763,279 - 62,766,043 (+)NCBICelera
RH 3.4 Map16573.12RGD
Cytogenetic Map16q12.3NCBI
Adrb3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495546313,663,064 - 13,665,553 (-)NCBIChiLan1.0ChiLan1.0
ADRB3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1834,440,099 - 34,444,043 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0837,263,730 - 37,267,475 (-)NCBIMhudiblu_PPA_v0panPan3
ADRB3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11627,445,601 - 27,446,796 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1627,445,601 - 27,447,521 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1627,962,835 - 27,964,030 (+)NCBI
ROS_Cfam_1.01629,344,866 - 29,346,061 (+)NCBI
UMICH_Zoey_3.11627,566,781 - 27,567,975 (+)NCBI
UNSW_CanFamBas_1.01628,144,259 - 28,145,454 (+)NCBI
UU_Cfam_GSD_1.01628,183,588 - 28,184,783 (+)NCBI
Adrb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494350,047,746 - 50,068,949 (+)NCBI
SpeTri2.0NW_0049367101,410,589 - 1,413,279 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADRB3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1835,993,553 - 35,998,200 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660526,000,510 - 6,004,793 (+)NCBIVero_WHO_p1.0
Adrb3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247805,653,499 - 5,656,138 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system hemolymphoid system respiratory system
High
Medium
Low 2
Below cutoff 4 2 3 1

Sequence


Reference Sequences
RefSeq Acc Id: NM_001099927   ⟹   NP_001093397
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11548,475,268 - 48,477,172 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021074691   ⟹   XP_020930350
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11548,468,803 - 48,478,370 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_020930350   ⟸   XM_021074691
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001093397   ⟸   NM_001099927
- UniProtKB: A0A8J3 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
G_PROTEIN_RECEP_F1_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015821 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025028700 UniProtKB/Swiss-Prot
  ENSSSCG00055006394 UniProtKB/Swiss-Prot
  ENSSSCG00065030134 UniProtKB/Swiss-Prot
  ENSSSCG00070026931 UniProtKB/Swiss-Prot
Ensembl Protein ENSSSCP00000016767 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00025016482 UniProtKB/Swiss-Prot
  ENSSSCP00055009757 UniProtKB/Swiss-Prot
  ENSSSCP00065017201 UniProtKB/Swiss-Prot
  ENSSSCP00070045782 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000017229 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00025038960 UniProtKB/Swiss-Prot
  ENSSSCT00055012382 UniProtKB/Swiss-Prot
  ENSSSCT00065040660 UniProtKB/Swiss-Prot
  ENSSSCT00070054010 UniProtKB/Swiss-Prot
InterPro ADR_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADRB3_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397356 UniProtKB/TrEMBL
NCBI Gene ADRB3 ENTREZGENE
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS ADRENERGICR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADRENRGCB3AR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2C9F3F6_PIG UniProtKB/TrEMBL
  A0A8J1_PIG UniProtKB/TrEMBL
  A0A8J3 ENTREZGENE, UniProtKB/TrEMBL
  ADRB3_PIG UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q9MZ00 UniProtKB/Swiss-Prot