SLC2A1 (solute carrier family 2 member 1) - Rat Genome Database

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Gene: SLC2A1 (solute carrier family 2 member 1) Sus scrofa
Analyze
Symbol: SLC2A1
Name: solute carrier family 2 member 1
RGD ID: 14011054
Description: ENCODES a protein that exhibits D-glucose transmembrane transporter activity (ortholog); dehydroascorbic acid transmembrane transporter activity (ortholog); glucose transmembrane transporter activity (ortholog); INVOLVED IN cellular hyperosmotic response (ortholog); cellular response to glucose starvation (ortholog); cellular response to mechanical stimulus (ortholog); PARTICIPATES IN facilitative sugar transporter mediated glucose transport pathway; Glut1 deficiency syndrome pathway; hypoxia inducible factor pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Ataxia (ortholog); benign epilepsy with centrotemporal spikes (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); caveola (ortholog); INTERACTS WITH aldehydo-D-glucose; amiloride; cyclosporin A
Type: protein-coding
RefSeq Status: MODEL
Also known as: glucose transport protein; GLUT1; solute carrier family 2 (facilitated glucose transporter), member 1; solute carrier family 2, facilitated glucose transporter member 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6168,534,655 - 168,690,095 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16168,535,398 - 168,561,170 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26156,057,568 - 156,059,070 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Alzheimer's disease  (ISO)
Ataxia  (ISO)
benign epilepsy with centrotemporal spikes  (ISO)
Breast Neoplasms  (ISO)
cataract  (ISO)
cerebellar ataxia  (ISO)
Charcot-Marie-Tooth disease dominant intermediate C  (ISO)
childhood absence epilepsy  (ISO)
childhood onset GLUT1 deficiency syndrome 2  (ISO)
Colonic Neoplasms  (ISO)
Developmental Disabilities  (ISO)
diabetes mellitus  (ISO)
Diabetic Nephropathies  (ISO)
Ductal Carcinoma  (ISO)
ductal carcinoma in situ  (ISO)
dystonia  (ISO)
dystonia 9  (ISO)
epilepsy  (ISO)
Experimental Diabetes Mellitus  (ISO)
Fetal Growth Retardation  (ISO)
genetic disease  (ISO)
glomerulosclerosis  (ISO)
GLUT1 Deficiency Syndrome  (ISO)
hemangioma  (ISO)
hepatocellular carcinoma  (ISO)
Hirschsprung's disease  (ISO)
hypertension  (ISO)
hypothyroidism  (ISO)
idiopathic generalized epilepsy 12  (ISO)
Infantile Capillary Hemangioma  (ISO)
inherited metabolic disorder  (ISO)
intellectual disability  (ISO)
Liver Neoplasms  (ISO)
malignant mesothelioma  (ISO)
microcephaly  (ISO)
middle cerebral artery infarction  (ISO)
migraine  (ISO)
myelomeningocele  (ISO)
Myocardial Reperfusion Injury  (ISO)
Neoplastic Cell Transformation  (ISO)
nephroblastoma  (ISO)
nervous system disease  (ISO)
obesity  (ISO)
osteoarthritis  (ISO)
Ovarian Neoplasms  (ISO)
Peritoneal Neoplasms  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (ISO)
Stomatin-Deficient Cryohydrocytosis with Mental Retardation, Seizures, Cataracts, and Massive Hepatosplenomegaly  (ISO)
type 2 diabetes mellitus  (ISO)
visual epilepsy  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:2472815   PMID:8521728   PMID:16259605   PMID:26030125   PMID:26924216  


Genomics

Comparative Map Data
SLC2A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6168,534,655 - 168,690,095 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16168,535,398 - 168,561,170 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26156,057,568 - 156,059,070 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC2A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl142,925,353 - 42,958,893 (-)EnsemblGRCh38hg38GRCh38
GRCh38142,925,353 - 42,958,868 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37143,391,024 - 43,424,539 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36143,164,102 - 43,197,088 (-)NCBINCBI36hg18NCBI36
Build 34143,060,611 - 43,093,594NCBI
Celera141,673,133 - 41,706,939 (-)NCBI
Cytogenetic Map1p34.2NCBI
HuRef141,511,000 - 41,544,561 (-)NCBIHuRef
CHM1_1143,507,796 - 43,541,586 (-)NCBICHM1_1
Slc2a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394118,965,942 - 118,994,527 (+)NCBIGRCm39mm39
GRCm39 Ensembl4118,965,908 - 118,995,180 (+)Ensembl
GRCm384119,108,745 - 119,137,330 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4119,108,711 - 119,137,983 (+)EnsemblGRCm38mm10GRCm38
MGSCv374118,781,350 - 118,809,935 (+)NCBIGRCm37mm9NCBIm37
MGSCv364118,606,700 - 118,635,259 (+)NCBImm8
Celera4117,836,249 - 117,864,839 (+)NCBICelera
Cytogenetic Map4D2.1NCBI
cM Map455.34NCBI
Slc2a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25132,717,196 - 132,745,416 (+)NCBI
Rnor_6.0 Ensembl5138,154,673 - 138,182,897 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05138,154,677 - 138,182,897 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05141,964,114 - 141,992,634 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45139,690,801 - 139,719,021 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15139,696,029 - 139,724,247 (+)NCBI
Celera5131,243,786 - 131,272,021 (+)NCBICelera
RH 3.4 Map5865.0RGD
Cytogenetic Map5q36NCBI
Slc2a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555372,408,042 - 2,439,511 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555372,408,042 - 2,438,788 (-)NCBIChiLan1.0ChiLan1.0
SLC2A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1143,600,733 - 43,634,143 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl143,600,733 - 43,634,143 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0142,224,273 - 42,257,184 (-)NCBIMhudiblu_PPA_v0panPan3
SLC2A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.115463,307 - 493,145 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl15463,237 - 493,140 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha15719,928 - 748,675 (+)NCBI
ROS_Cfam_1.015546,520 - 575,271 (+)NCBI
UMICH_Zoey_3.115456,107 - 484,827 (+)NCBI
UNSW_CanFamBas_1.015515,411 - 544,075 (+)NCBI
UU_Cfam_GSD_1.015532,601 - 561,334 (+)NCBI
Slc2a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505858,381,102 - 58,411,854 (-)NCBI
SpeTri2.0NW_00493647424,205,878 - 24,236,611 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC2A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12089,974,567 - 90,007,977 (+)NCBI
ChlSab1.1 Ensembl2090,002,030 - 90,008,033 (+)Ensembl
Vero_WHO_p1.0NW_02366603326,904,125 - 26,937,791 (-)NCBI
Slc2a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248922,110,310 - 2,148,023 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1 11 1
Low 9 4 3 4 2 12 2 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: XM_021096908   ⟹   XP_020952567
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.16168,535,398 - 168,561,170 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020952567 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABS50358 (Get FASTA)   NCBI Sequence Viewer  
  AMN88559 (Get FASTA)   NCBI Sequence Viewer  
  CAA34904 (Get FASTA)   NCBI Sequence Viewer  
  JAA53585 (Get FASTA)   NCBI Sequence Viewer  
  P20303 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020952567   ⟸   XM_021096908
- Sequence:
Protein Domains
MFS   P4Hc


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000023920 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00025013928 UniProtKB/Swiss-Prot
  ENSSSCG00030031281 UniProtKB/Swiss-Prot
  ENSSSCG00035045709 UniProtKB/Swiss-Prot
  ENSSSCG00040019486 UniProtKB/Swiss-Prot
  ENSSSCG00045008726 UniProtKB/Swiss-Prot
  ENSSSCG00050024549 UniProtKB/Swiss-Prot
  ENSSSCG00055014418 UniProtKB/Swiss-Prot
  ENSSSCG00060050095 UniProtKB/Swiss-Prot
  ENSSSCG00065004975 UniProtKB/Swiss-Prot
  ENSSSCG00070029283 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000019443 UniProtKB/TrEMBL
  ENSSSCP00000019985 UniProtKB/TrEMBL
  ENSSSCP00000023111 UniProtKB/TrEMBL
  ENSSSCP00000062057 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSSSCP00025007494 UniProtKB/Swiss-Prot
  ENSSSCP00030019635 UniProtKB/Swiss-Prot
  ENSSSCP00035024456 UniProtKB/Swiss-Prot
  ENSSSCP00040011128 UniProtKB/Swiss-Prot
  ENSSSCP00045010232 UniProtKB/Swiss-Prot
  ENSSSCP00050013773 UniProtKB/Swiss-Prot
  ENSSSCP00055022669 UniProtKB/Swiss-Prot
  ENSSSCP00060029210 UniProtKB/Swiss-Prot
  ENSSSCP00065002969 UniProtKB/Swiss-Prot
  ENSSSCP00070050017 UniProtKB/TrEMBL
  ENSSSCP00070050022 UniProtKB/Swiss-Prot
  ENSSSCP00070050024 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000025559 UniProtKB/TrEMBL
  ENSSSCT00000028401 UniProtKB/TrEMBL
  ENSSSCT00000029090 UniProtKB/TrEMBL
  ENSSSCT00000072802 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSSSCT00025018551 UniProtKB/Swiss-Prot
  ENSSSCT00030043368 UniProtKB/Swiss-Prot
  ENSSSCT00035060762 UniProtKB/Swiss-Prot
  ENSSSCT00040026305 UniProtKB/Swiss-Prot
  ENSSSCT00045014749 UniProtKB/Swiss-Prot
  ENSSSCT00050033067 UniProtKB/Swiss-Prot
  ENSSSCT00055028441 UniProtKB/Swiss-Prot
  ENSSSCT00060068069 UniProtKB/Swiss-Prot
  ENSSSCT00065006791 UniProtKB/Swiss-Prot
  ENSSSCT00070058794 UniProtKB/TrEMBL
  ENSSSCT00070058799 UniProtKB/Swiss-Prot
  ENSSSCT00070058801 UniProtKB/TrEMBL
InterPro Glu_transpt_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_sugar_transport-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P3H UniProtKB/TrEMBL
  P3H1 UniProtKB/TrEMBL
  Pro_4_hyd_alph UniProtKB/TrEMBL
  Sugar/inositol_transpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sugar_transporter_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
NCBI Gene SLC2A1 ENTREZGENE
PANTHER PTHR14049 UniProtKB/TrEMBL
  PTHR14049:SF5 UniProtKB/TrEMBL
Pfam Sugar_tr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS GLUCTRSPORT1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUGRTRNSPORT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MFS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUGAR_TRANSPORT_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUGAR_TRANSPORT_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART P4Hc UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48452 UniProtKB/TrEMBL
TIGRFAMs TIGR00879 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140H1A1_PIG UniProtKB/TrEMBL
  A0A4X1W1F4_PIG UniProtKB/TrEMBL
  A0A4X1W6C5_PIG UniProtKB/TrEMBL
  A7LGJ4_PIG UniProtKB/TrEMBL
  GTR1_PIG UniProtKB/Swiss-Prot
  I3L5Z2_PIG UniProtKB/TrEMBL
  I3L7I0_PIG UniProtKB/TrEMBL
  I3LGB8_PIG UniProtKB/TrEMBL
  P20303 ENTREZGENE
UniProt Secondary A0A286ZMA8 UniProtKB/TrEMBL
  K9IVJ7 UniProtKB/Swiss-Prot