DPYS (dihydropyrimidinase) - Rat Genome Database

Name: DPYS
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: DPYS (dihydropyrimidinase) Sus scrofa

Analyze

Symbol:

DPYS

Name:

dihydropyrimidinase

RGD ID:

13950491

Description:

ENCODES a protein that exhibits amino acid binding (ortholog); dihydropyrimidinase activity (ortholog); identical protein binding (ortholog); INVOLVED IN beta-alanine metabolic process (ortholog); CMP catabolic process (ortholog); dCMP catabolic process (ortholog); PARTICIPATES IN beta-alanine metabolic pathway; beta-ureidopropionase deficiency pathway; carnosinemia pathway; ASSOCIATED WITH dihydropyrimidinase deficiency (ortholog); Experimental Liver Cirrhosis (ortholog); purine-pyrimidine metabolic disorder (ortholog); FOUND IN cytosol (ortholog); protein-containing complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Dog

Squirrel

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DPYS (dihydropyrimidinase)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Dpys (dihydropyrimidinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Dpys (dihydropyrimidinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dpys (dihydropyrimidinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DPYS (dihydropyrimidinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DPYS (dihydropyrimidinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dpys (dihydropyrimidinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	DPYS (dihydropyrimidinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dpys (dihydropyrimidinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	32,789,460 - 32,879,489 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	32,791,152 - 32,879,489 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	35,528,834 - 35,616,166 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

dihydropyrimidinase deficiency (ISO)

Experimental Liver Cirrhosis (ISO)

purine-pyrimidine metabolic disorder (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

beta-alanine metabolic process (ISO)

CMP catabolic process (IEA,ISO)

dCMP catabolic process (IEA,ISO)

dUMP catabolic process (IEA,ISO)

pyrimidine nucleobase catabolic process (IBA)

thymine catabolic process (ISO)

UMP catabolic process (IEA,ISO)

uracil catabolic process (IEA,ISO)

uracil metabolic process (ISO)

Cellular Component

cytoplasm (IEA)

cytosol (IEA,ISO)

protein-containing complex (ISO)

Molecular Function

amino acid binding (ISO)

dihydropyrimidinase activity (IBA,ISO)

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (IEA)

identical protein binding (ISO)

phosphoprotein binding (IEA,ISO)

protein binding (ISO)

thymine binding (ISO)

uracil binding (ISO)

zinc ion binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

beta-alanine metabolic pathway (ISO)

beta-ureidopropionase deficiency pathway (ISO)

carnosinemia pathway (ISO)

dihydropyrimidinase deficiency pathway (ISO)

GABA aminotransferase deficiency pathway (ISO)

mitochondrial neurogastrointestinal encephalopathy syndrome pathway (ISO)

orotic aciduria 1 pathway (ISO)

pyrimidine metabolic pathway (ISO)

References

Additional References at PubMed

PMID:14681463

Genomics

Comparative Map Data

DPYS
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	32,789,460 - 32,879,489 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	32,791,152 - 32,879,489 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	35,528,834 - 35,616,166 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DPYS
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	8	104,330,324 - 104,467,055 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	8	104,379,429 - 104,467,074 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	8	105,391,659 - 105,479,283 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	8	105,391,652 - 105,479,281 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	105,460,829 - 105,548,453 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	8	105,460,828 - 105,548,453	NCBI
Celera	8	101,578,319 - 101,665,933 (-)	NCBI
Cytogenetic Map	8	q22.3	NCBI
HuRef	8	100,592,683 - 100,680,266 (-)	NCBI		HuRef
CHM1_1	8	105,432,468 - 105,520,073 (-)	NCBI		CHM1_1

Dpys
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	39,631,881 - 39,720,866 (-)	NCBI	GRCm39		mm39
GRCm38	15	39,768,485 - 39,857,470 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	39,768,487 - 39,857,470 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	39,600,031 - 39,689,016 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	15	39,598,559 - 39,687,541 (-)	NCBI			mm8
Celera	15	40,252,611 - 40,341,397 (-)	NCBI		Celera
Cytogenetic Map	15	B3.1	NCBI

Dpys
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	70,822,648 - 70,929,255 (-)	NCBI
Rnor_6.0 Ensembl	7	78,769,807 - 78,847,974 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	7	78,769,918 - 78,847,941 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	7	78,796,405 - 78,873,615 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	75,368,238 - 75,446,160 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	7	75,449,118 - 75,466,890 (-)	NCBI
Celera	7	67,904,867 - 67,982,691 (-)	NCBI		Celera
Cytogenetic Map	7	q31	NCBI

Dpys
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955417	28,185,407 - 28,244,307 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955417	28,183,771 - 28,244,309 (-)	NCBI	ChiLan1.0	ChiLan1.0

DPYS
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	8	103,160,922 - 103,248,303 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	103,160,922 - 103,248,303 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	8	101,008,090 - 101,096,234 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

DPYS
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	13	5,583,801 - 5,659,463 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	13	5,583,795 - 5,659,355 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Dpys
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936470	39,564,431 - 39,637,394 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DPYS
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	99,216,623 - 99,303,969 (-)	NCBI
ChlSab1.1 Ensembl	8	99,216,354 - 99,303,282 (-)	Ensembl

Dpys
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624763	20,618,515 - 20,680,790 (-)	NCBI

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	nervous system	renal system	reproductive system	respiratory system
High
Medium						2		2
Low	2			3	1		1	1
Below cutoff	5	3	3	2	12		1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_001925251	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013996559	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021089028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK233428	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU222531	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU407249	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01016434	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSSSCT00000037104 ⟹ ENSSSCP00000043882

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	4	32,789,460 - 32,879,489 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000047501 ⟹ ENSSSCP00000057175

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	4	32,791,950 - 32,879,489 (+)	Ensembl

RefSeq Acc Id:

XM_001925251 ⟹ XP_001925286

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	4	32,791,921 - 32,879,484 (+)	NCBI

Sequence:

show sequence

ATAAACCTGGAGCCGAACCCTAGGAGCTGCTCCCAGGCACCTGGAGGGAGGGCGAGCCCATAGC
GCATGCGCCCCTCGCCATGGCGGCGCCGTCGAGGCTCCTCATCCGTGGCGGGCGCGTGGTGAAC
GACGATTCCTCGCAGGTGGCCGATGTGCTGGTGGAGGACGGCGTGGTGCGAGCGCTCGGACGCG
ACCTGCTGCCGCCCGGGGGTGCGCCCGCGGGGCTGCGGGTCCTCGACGCCGCCGGCAAGCTGGT
CCTGCCGGGAGGCATCGACACGCACACACACATGCAGTTCCCCTTTATGGGGTCGCGCTCCGTC
GACGACTTCCACCAGGGCACCAAGGCTGCCCTGGCAGGAGGCACCACCATGATCATTGATTTTG
CCATTCCTCACAAAGGCCATTCCCTCGTCGAGGCCTTTGAGACCTGGAGAAGCTGGGCTGATTC
CAAAGTCTGCTGCGACTACAGCCTTCATGTGGCAGTGACGTGGTGGAGTGACCAGGTTAAAGAA
GAAATGAAAATCCTTACACAAGAGAAAGGTGTGAACTCTTTTAAGATGTTTATGGCCTATAAAG
ACCTGTATATGTTGAGAGATGTGGAGCTGTACACAGTCTTTTCTTGGTGCAAGGAAATTGGAGC
GATTGCTCAAGTTCATGCAGAAAATGGAGACCTCATTGCAGAGGGAGCAAAGAAGATGTTGGCA
TTGGGAATAACAGGTCCTGAGGGCCACGAGCTGTGCCGCCCGGAAGCGGTGGAGGCAGAAGCCA
CGCTGAGGGCCATCACCATAGCCAGCGCTGTGAACTGCCCTCTCTATGTCGTGCATGTCATGAG
CAAGTCAGCAGCGAGGGTGATAGCAGATGCCAGGAGAGACGGGAAGGTGGTCTATGGAGAACCC
ATTGCAGCAGGCCTTGGCACAGATGGCACTCACTACTGGAACAGAGACTGGCACCATGCAGCCC
ACCATGTTATGGGTCCACCCCTGCGACCAGACCCTTCAACGCCTGACTTCCTCCTGAATCTATT
GGCTAATGATGATCTAACCACAACAGGGTCTGATCACTGCACTTTCAACACCTGCCAGAAAGCT
CTTGGAAAGGATGATTTTACTAAGATTCCCAATGGAGTGAATGGTGTTGAGGACCGGATGTCAG
TAATCTGGGAAAAAGCCGTGCACAGTGGCAAAATGGATGAAAACCGATTTGTGGCAGTTACTAG
CACAAATGCAGCTAAAATCTTTAATCTCTATCCAAGAAAAGGAAGAATAGCTGTGGGCTCAGAT
GCTGACATTGTGATTTGGGACCCAAAAGCTACAAGGACAATTTCAGCAAAAACTCATCATCAGG
CTGTTAACTTCAACATCTTCGAGGGCATGGTTTGCCACGGGGTGCCCCTGGTGACTATTTCAAG
AGGCAGAGTGGTATATGAAGCTGGAGTCTTCACTGTCACAGCAGGACACGGGAAGTTTATTCCC
CGTAAACCATTTGCTGACTATATTTACAAACGGATCAAGCAGCGGGATGAGACATGCGCACCTA
CCCCCGTGGAGCGTGAACCCTATAAGGGAGAAGTCGTCACACTGAAATCCAGAGGGACAGAAGA
CGACTCTACAGCTGGGACCAGCAAACAGGCCCACCACTGAGCCGGGGGCTGGCAGTAAAATCAG
AGAAAAGGATGCTGCTGTTCCCATCCCAGTTAAACGTTGTCAGCCCATGGAGAAGCAGGCCTTA
TTTCAACTCACCAAGATCCTTTTGAAAAAATAATCGCTCTAGGCTTCTTTGATTTCCTTTCAGA
AGGAATAGCTGTCTTTCTCACTGTGACTTTGTTGCAGTGTAAGATTGAAGATATAAATGAATAT
TATTGTGATGGAAAATCTGTGTGAAAATTCATTGATGATAGTTTAAAATGTCATCTTTGCTTTT
CTTACTTGAATTTTTAAAAATCACTTTCCTGTTTAAAGTTTTTTTTCCAATATATACATTTGTT
TAAAAATAGCCAACTCTGTGATTTTACAATCTATTGTAATTCATAAGCATTTAGATCTTTATTG
TAATTAATAAACATTTAGATCTTCA

hide sequence

RefSeq Acc Id:

XM_013996559 ⟹ XP_013852013

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	4	32,791,908 - 32,879,489 (+)	NCBI

Sequence:

show sequence

CAGCTGCCAGTTGATAAACCTGGAGCCGAACCCTAGGAGCTGCTCCCAGGCACCTGGAGGGAGG
GCGAGCCCATAGCGCATGCGCCCCTCGCCATGGCGGCGCCGTCGAGGCTCCTCATCCGTGGCGG
GCGCGTGGTGAACGACGATTCCTCGCAGGTGGCCGATGTGCTGGTGGAGGACGGCGTGGTGCGA
GCGCTCGGACGCGACCTGCTGCCGCCCGGGGGTGCGCCCGCGGGGCTGCGGGTCCTCGACGCCG
CCGGCAAGCTGGTCCTGCCGGGAGGCATCGACACGCACACACACATGCAGTTCCCCTTTATGGG
GTCGCGCTCCGTCGACGACTTCCACCAGGGCACCAAGGCTGCCCTGGCAGGAGGCACCACCATG
ATCATTGATTTTGCCATTCCTCACAAAGGCCATTCCCTCGTCGAGGCCTTTGAGACCTGGAGAA
GCTGGGCTGATTCCAAAGTCTGCTGCGACTACAGCCTTCATGTGGCAGTGACGTGGTGGAGTGA
CCAGGTTAAAGAAGAAATGAAAATCCTTACACAAGAGAAAGGTGTGAACTCTTTTAAGATGTTT
ATGGCCTATAAAGACCTGTATATGTTGAGAGATGTGGAGCTGTACACAGTCTTTTCTTGGTGCA
AGGAAATTGGAGCGATTGCTCAAGTTCATGCAGAAAATGGAGACCTCATTGCAGAGGGAGCAAA
GAAGATGTTGGCATTGGGAATAACAGGTCCTGAGGGCCACGAGCTGTGCCGCCCGGAAGCGGTG
GAGGCAGAAGCCACGCTGAGGGCCATCACCATAGCCAGCGCTGTGAACTGCCCTCTCTATGTCG
TGCATGTCATGAGCAAGTCAGCAGCGAGGGTGATAGCAGATGCCAGGAGAGACGGGAAGGTGGT
CTATGGAGAACCCATTGCAGCAGGCCTTGGCACAGATGGCACTCACTACTGGAACAGAGACTGG
CACCATGCAGCCCACCATGTTATGGGTCCACCCCTGCGACCAGACCCTTCAACGCCTGACTTCC
TCCTGAATCTATTGGCTAATGATGATCTAACCACAACAGGGTCTGATCACTGCACTTTCAACAC
CTGCCAGAAAGCTCTTGGAAAGGATGATTTTACTAAGATTCCCAATGGAGTGAATGGTGTTGAG
GACCGGATGTCAGTAATCTGGGAAAAAGCCGTGCACAGTGGCAAAATGGATGAAAACCGATTTG
TGGCAGTTACTAGCACAAATGCAGCTAAAATCTTTAATCTCTATCCAAGAAAAGGAAGAATAGC
TGTGGGCTCAGATGCTGACATTGTGATTTGGGACCCAAAAGCTACAAGGACAATTTCAGCAAAA
ACTCATCATCAGGCTGTTAACTTCAACATCTTCGAGGGCATGGTTTGCCACGGGGTGCCCCTGG
TGACTATTTCAAGAGGCAGAGTGGTATATGAAGCTGGAGTCTTCACTGTCACAGCAGGACACGG
GAAGTTTATTCCCCGTAAACCATTTGCTGACTATATTTACAAACGGATCAAGCAGCGGGATGAG
GTAAAATCAGAGAAAAGGATGCTGCTGTTCCCATCCCAGTTAAACGTTGTCAGCCCATGGAGAA
GCAGGCCTTATTTCAACTCACCAAGATCCTTTTGAAAAAATAATCGCTCTAGGCTTCTTTGATT
TCCTTTCAGAAGGAATAGCTGTCTTTCTCACTGTGACTTTGTTGCAGTGTAAGATTGAAGATAT
AAATGAATATTATTGTGATGGAAAATCTGTGTGAAAATTCATTGATGATAGTTTAAAATGTCAT
CTTTGCTTTTCTTACTTGAATTTTTAAAAATCACTTTCCTGTTTAAAGTTTTTTTTCCAATATA
TACATTTGTTTAAAAATAGCCAACTCTGTGATTTTACAATCTATTGTAATTCATAAGCATTTAG
ATCTTTATTGTAATTAATAAACATTTAGATCTTCATTTTA

hide sequence

RefSeq Acc Id:

XM_021089028 ⟹ XP_020944687

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	4	32,791,152 - 32,878,396 (+)	NCBI

Sequence:

show sequence

TCACATCCATCAAAGCAAATCTGGAAGGGAAGAACGAGCATTATCTCAGTTGCAGACATGAGAA
AACTGAGGAACCGAGGGGACAAAAGATTTACGCGAAGACCTCTAAGCTGGTTTTGTGGAACAGC
TGGGAGCAAAACCCTAGCTCCTTAGAAGTACATTACCTGCTATTTTCCAAAACAACAACAACAA
CAACAACAACAACGAAAACCAAACCTTGCTGTTTGGTACAGACACACTCTTCATAAAGGGAAGA
AATGAGGTGGATTTCTTTCCCCAAAGCAAAAGGACAACAAACGACCCTCGCCTCCAAAGCAAAG
ATCTTTCCCTTCCAGTGACTGACACCTGGTTCAGGGCAGCCGAACCTTTGGCATCTGCAACGCA
AACGGGCCTTGGGTTGGACCCCAGCCTTTTGGCTCAGACCCAGCACCACCCACCCCTCCCCGCC
TCGGGGGTGGAGCTGCCCCCACCCCCACCCCCAGCTGCCAGTTGATAAACCTGGAGCCGAACCC
TAGGAGCTGCTCCCAGGCACCTGGAGGGAGGGCGAGCCCATAGCGCATGCGCCCCTCGCCATGG
CGGCGCCGTCGAGGCTCCTCATCCGTGGCGGGCGCGTGGTGAACGACGATTCCTCGCAGGTGGC
CGATGTGCTGGTGGAGGACGGCGTGGTGCGAGCGCTCGGACGCGACCTGCTGCCGCCCGGGGGT
GCGCCCGCGGGGCTGCGGGTCCTCGACGCCGCCGGCAAGCTGGTCCTGCCGGGAGGCATCGACA
CGCACACACACATGCAGTTCCCCTTTATGGGGTCGCGCTCCGTCGACGACTTCCACCAGGGCAC
CAAGGCTGCCCTGGCAGGAGGCACCACCATGATCATTGATTTTGCCATTCCTCACAAAGGCCAT
TCCCTCGTCGAGGCCTTTGAGACCTGGAGAAGCTGGGCTGATTCCAAAGTCTGCTGCGACTACA
GCCTTCATGTGGCAGTGACGTGGTGGAGTGACCAGGTTAAAGAAGAAATGAAAATCCTTACACA
AGAGAAAGGTGTGAACTCTTTTAAGATGTTTATGGCCTATAAAGACCTGTATATGTTGAGAGAT
GTGGAGCTGTACACAGTCTTTTCTTGGTGCAAGGAAATTGGAGCGATTGCTCAAGTTCATGCAG
AAAATGGAGACCTCATTGCAGAGGGAGCAAAGAAGATGTTGGCATTGGGAATAACAGGTCCTGA
GGGCCACGAGCTGTGCCGCCCGGAAGCGGTGGAGGCAGAAGCCACGCTGAGGGCCATCACCATA
GCCAGCGCTGTGAACTGCCCTCTCTATGTCGTGCATGTCATGAGCAAGTCAGCAGCGAGGGTGA
TAGCAGATGCCAGGAGAGACGGGAAGGTGGTCTATGGAGAACCCATTGCAGCAGGCCTTGGCAC
AGATGGCACTCACTACTGGAACAGAGACTGGCACCATGCAGCCCACCATGTTATGGGTCCACCC
CTGCGACCAGACCCTTCAACGCCTGACTTCCTCCTGAATCTATTGGCTAATGATGATCTAACCA
CAACAGGGTCTGATCACTGCACTTTCAACACCTGCCAGAAAGCTCTTGGAAAGGATGATTTTAC
TAAGATTCCCAATGGAGTGAATGGTGTTGAGGACCGGATGTCAGTAATCTGGGAAAAAGCCGTG
CACAGTGGCAAAATGGATGAAAACCGATTTGTGGCAGTTACTAGCACAAATGCAGCTAAAATCT
TTAATCTCTATCCAAGAAAAGGAAGAATAGCTGTGGGCTCAGATGCTGACATTGTGATTTGGGA
CCCAAAAGCTACAAGGACAATTTCAGCAAAAACTCATCATCAGGCTGTTAACTTCAACATCTTC
GAGGGCATGGTTTGCCACGGGGTGCCCCTGGTGACTATTTCAAGAGGCAGAGTGGTATATGAAG
CTGGAGTCTTCACTGTCACAGCAGGACACGGGAAGTTTATTCCCCGTAAACCATTTGCTGACTA
TATTTACAAACGGATCAAGCAGCGGGATGAGACATGCGCACCTACCCCCGTGGAGCGTGAACCC
TATAAGGGAGAAGTCGTCACACTGAAATCCAGAGGGACAGAAGACGACTCTACAGCTGGGACCA
GCAAACAGGCCCACCACTGAGCCGGGGGCTGGCAGTAAGGAACAGTGGACAGAGAGTTTTTCTG
TAACACAGCATGTGAAATTAGCATATCTCTTGCTTTGGAAGCATTTGAAGAGTTCAAGGTCAAG
GTCAAAAACTTCAAAGTAACGGAAGACTCAAGGATAGTTTAGCCAAAGAGAAGACTGGTAAAAG
GGCTCTTGACGTAGAACCCTTGGGTGAGCCTGCCAGGCTGAAGAAGGCCTTGGCCTGGCTAGAG
ATTTATTCTCTGAGATGTTAGGAAGCACTCCTCAGAGGCTTGGAGAATCAAATGTGTGCAAGAG
GCTGGTAACACGGAGGGACCTGTTATTGAGGGAAGTTGGCACTGCTTCAAACAGAAAGTACAGG
TTCATAGTCAAAATTTATAAATTGTTTACTCAGGACTTTAAAAAAAATGAATCTTTGTATTGTA
AAAGTAACTATCTTCTGGAACTTAGAATGAATAAGAAATGAATCAAATATTGCTTTCAAGAAAA
TTATTTGATAATACTTCATCAAAAAATATACTTATTTCACACTTAATTTTATAATAATTTTATG
GATATGGTCATTTACAAATATTTGAGTGCTTCATTGATTCTCAGTTTCTGAAATTCAAATCTTT
CTTTTTGAAGCGCCTGTTACCATCATCCTTGTCGATTTTCTTTTTCTTTTCTTCCCCAATTTGT
TTTCTGATCCTG

hide sequence

Protein Sequences


Protein RefSeqs	XP_001925286	(Get FASTA)	NCBI Sequence Viewer
	XP_013852013	(Get FASTA)	NCBI Sequence Viewer
	XP_020944687	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_020944687 ⟸ XM_021089028

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAAPSRLLIRGGRVVNDDSSQVADVLVEDGVVRALGRDLLPPGGAPAGLRVLDAAGKLVLPGGI
DTHTHMQFPFMGSRSVDDFHQGTKAALAGGTTMIIDFAIPHKGHSLVEAFETWRSWADSKVCCD
YSLHVAVTWWSDQVKEEMKILTQEKGVNSFKMFMAYKDLYMLRDVELYTVFSWCKEIGAIAQVH
AENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYVVHVMSKSAAR
VIADARRDGKVVYGEPIAAGLGTDGTHYWNRDWHHAAHHVMGPPLRPDPSTPDFLLNLLANDDL
TTTGSDHCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKAVHSGKMDENRFVAVTSTNAAK
IFNLYPRKGRIAVGSDADIVIWDPKATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVY
EAGVFTVTAGHGKFIPRKPFADYIYKRIKQRDETCAPTPVEREPYKGEVVTLKSRGTEDDSTAG
TSKQAHH

hide sequence

RefSeq Acc Id:

XP_013852013 ⟸ XM_013996559

- Peptide Label:

isoform X2

- Sequence:

show sequence

MAAPSRLLIRGGRVVNDDSSQVADVLVEDGVVRALGRDLLPPGGAPAGLRVLDAAGKLVLPGGI
DTHTHMQFPFMGSRSVDDFHQGTKAALAGGTTMIIDFAIPHKGHSLVEAFETWRSWADSKVCCD
YSLHVAVTWWSDQVKEEMKILTQEKGVNSFKMFMAYKDLYMLRDVELYTVFSWCKEIGAIAQVH
AENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYVVHVMSKSAAR
VIADARRDGKVVYGEPIAAGLGTDGTHYWNRDWHHAAHHVMGPPLRPDPSTPDFLLNLLANDDL
TTTGSDHCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKAVHSGKMDENRFVAVTSTNAAK
IFNLYPRKGRIAVGSDADIVIWDPKATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVY
EAGVFTVTAGHGKFIPRKPFADYIYKRIKQRDEVKSEKRMLLFPSQLNVVSPWRSRPYFNSPRS
F

hide sequence

RefSeq Acc Id:	XP_001925286 ⟸ XM_001925251
- Peptide Label:	isoform X1
- UniProtKB:	F1S1E7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAPSRLLIRGGRVVNDDSSQVADVLVEDGVVRALGRDLLPPGGAPAGLRVLDAAGKLVLPGGI DTHTHMQFPFMGSRSVDDFHQGTKAALAGGTTMIIDFAIPHKGHSLVEAFETWRSWADSKVCCD YSLHVAVTWWSDQVKEEMKILTQEKGVNSFKMFMAYKDLYMLRDVELYTVFSWCKEIGAIAQVH AENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYVVHVMSKSAAR VIADARRDGKVVYGEPIAAGLGTDGTHYWNRDWHHAAHHVMGPPLRPDPSTPDFLLNLLANDDL TTTGSDHCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKAVHSGKMDENRFVAVTSTNAAK IFNLYPRKGRIAVGSDADIVIWDPKATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVY EAGVFTVTAGHGKFIPRKPFADYIYKRIKQRDETCAPTPVEREPYKGEVVTLKSRGTEDDSTAG TSKQAHH hide sequence

RefSeq Acc Id:

ENSSSCP00000043882 ⟸ ENSSSCT00000037104

RefSeq Acc Id:

ENSSSCP00000057175 ⟸ ENSSSCT00000047501

Protein Domains

Amidohydro-rel

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000006040	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSSSCP00000043882	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCP00000057175	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000037104	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCT00000047501	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	2.30.40.10	UniProtKB/TrEMBL
InterPro	Amidohydro-rel	UniProtKB/TrEMBL
	Hydantoinase/dihydroPyrase	UniProtKB/TrEMBL
	Metal-dep_hydrolase_composite	UniProtKB/TrEMBL
	Metal_Hydrolase	UniProtKB/TrEMBL
KEGG Report	ssc:100156500	UniProtKB/TrEMBL
NCBI Gene	DPYS	ENTREZGENE
Pfam	Amidohydro_1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF51338	UniProtKB/TrEMBL
	SSF51556	UniProtKB/TrEMBL
TIGRFAMs	D-hydantoinase	UniProtKB/TrEMBL
UniProt	A0A287BLX5_PIG	UniProtKB/TrEMBL
	A0A480J570_PIG	UniProtKB/TrEMBL
	F1S1E7	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:87429	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB