| Symbol: |
REN |
| Name: |
renin |
| RGD ID: |
13854518 |
| Description: |
ENCODES a protein that exhibits endopeptidase activity (ortholog); insulin-like growth factor receptor binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN amyloid-beta metabolic process (ortholog); angiotensin maturation (ortholog); cellular response to xenobiotic stimulus (ortholog); PARTICIPATES IN benazepril pharmacodynamics pathway; candesartan pharmacodynamics pathway; captopril pharmacodynamics pathway; ASSOCIATED WITH acute kidney failure (ortholog); Albuminuria (ortholog); anemia (ortholog); FOUND IN extracellular space (ortholog) |
| Type: |
protein-coding
|
| RefSeq Status: |
MODEL |
| RGD Orthologs |
|
| Alliance Orthologs |
|
| More Info |
more info ...
|
| More Info |
| Species |
Gene symbol and name |
Data Source |
Assertion derived from |
less info ...
|
| Orthologs 1 |
| Homo sapiens (human): |
REN (renin) |
HGNC |
Ensembl, NCBI, OrthoDB |
| Mus musculus (house mouse): |
Ren1 (renin 1 structural) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
| Rattus norvegicus (Norway rat): |
Ren (renin) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
| Chinchilla lanigera (long-tailed chinchilla): |
Ren (renin) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
| Pan paniscus (bonobo/pygmy chimpanzee): |
REN (renin) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
| Canis lupus familiaris (dog): |
REN (renin) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
| Ictidomys tridecemlineatus (thirteen-lined ground squirrel): |
Ren (renin) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
| Chlorocebus sabaeus (green monkey): |
REN (renin) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
| Heterocephalus glaber (naked mole-rat): |
Ren (renin) |
Transitive Ortholog Pipeline |
Transitive Ortholog Pipeline |
|
| Latest Assembly: |
Sscrofa11.1 - Pig Sscrofa11.1 Assembly |
| Position: |
| Pig Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| Sscrofa11.1 Ensembl | 9 | 64,809,146 - 64,822,658 (-) | Ensembl | Sscrofa11.1 | | susScr11 | Sscrofa11.1 | | Sscrofa11.1 | 9 | 64,809,143 - 64,822,605 (-) | NCBI | Sscrofa11.1 | Sscrofa11.1 | susScr11 | Sscrofa11.1 | | Sscrofa10.2 | 9 | 71,147,542 - 71,151,808 (-) | NCBI | Sscrofa10.2 | Sscrofa10.2 | susScr3 | |
|
| JBrowse: |
View Region in Genome Browser (JBrowse)
|
| Model |
|
Imported Annotations - SMPDB
REN
(Sus scrofa - pig) |
| Pig Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| Sscrofa11.1 Ensembl | 9 | 64,809,146 - 64,822,658 (-) | Ensembl | Sscrofa11.1 | | susScr11 | Sscrofa11.1 | | Sscrofa11.1 | 9 | 64,809,143 - 64,822,605 (-) | NCBI | Sscrofa11.1 | Sscrofa11.1 | susScr11 | Sscrofa11.1 | | Sscrofa10.2 | 9 | 71,147,542 - 71,151,808 (-) | NCBI | Sscrofa10.2 | Sscrofa10.2 | susScr3 | |
|
REN
(Homo sapiens - human) |
| Human Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| GRCh38 | 1 | 204,154,819 - 204,166,337 (-) | NCBI | GRCh38 | GRCh38 | hg38 | GRCh38 | | GRCh38.p14 Ensembl | 1 | 204,154,819 - 204,190,324 (-) | Ensembl | GRCh38 | | hg38 | GRCh38 | | GRCh37 | 1 | 204,123,947 - 204,135,465 (-) | NCBI | GRCh37 | GRCh37 | hg19 | GRCh37 | | Build 36 | 1 | 202,390,571 - 202,402,088 (-) | NCBI | NCBI36 | Build 36 | hg18 | NCBI36 | | Build 34 | 1 | 200,855,604 - 200,867,122 | NCBI | | | | | | Celera | 1 | 177,259,194 - 177,270,715 (-) | NCBI | | Celera | | | | Cytogenetic Map | 1 | q32.1 | NCBI | | | | | | HuRef | 1 | 175,289,120 - 175,300,481 (-) | NCBI | | HuRef | | | | CHM1_1 | 1 | 205,547,624 - 205,559,145 (-) | NCBI | | CHM1_1 | | | | T2T-CHM13v2.0 | 1 | 203,418,967 - 203,430,485 (-) | NCBI | | T2T-CHM13v2.0 | | |
|
Ren1
(Mus musculus - house mouse) |
| Mouse Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| GRCm39 | 1 | 133,278,412 - 133,288,058 (+) | NCBI | GRCm39 | GRCm39 | mm39 | | | GRCm39 Ensembl | 1 | 133,278,248 - 133,288,063 (+) | Ensembl | | GRCm39 Ensembl | | | | GRCm38 | 1 | 133,350,674 - 133,360,320 (+) | NCBI | GRCm38 | GRCm38 | mm10 | GRCm38 | | GRCm38.p6 Ensembl | 1 | 133,350,510 - 133,360,325 (+) | Ensembl | GRCm38 | | mm10 | GRCm38 | | MGSCv37 | 1 | 135,247,251 - 135,256,894 (+) | NCBI | GRCm37 | MGSCv37 | mm9 | NCBIm37 | | MGSCv36 | 1 | 135,178,238 - 135,187,863 (+) | NCBI | | MGSCv36 | mm8 | | | Celera | 1 | 135,963,151 - 135,972,794 (+) | NCBI | | Celera | | | | Cytogenetic Map | 1 | E4 | NCBI | | | | | | cM Map | 1 | 57.91 | NCBI | | | | |
|
Ren
(Rattus norvegicus - Norway rat) |
| Rat Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| GRCr8 | 13 | 47,348,312 - 47,359,539 (+) | NCBI | | GRCr8 | | | | mRatBN7.2 | 13 | 44,796,260 - 44,807,491 (+) | NCBI | mRatBN7.2 | mRatBN7.2 | | | | mRatBN7.2 Ensembl | 13 | 44,796,091 - 44,807,489 (+) | Ensembl | | mRatBN7.2 Ensembl | | | | UTH_Rnor_SHR_Utx | 13 | 47,406,270 - 47,416,579 (+) | NCBI | Rnor_SHR | UTH_Rnor_SHR_Utx | | | | UTH_Rnor_SHRSP_BbbUtx_1.0 | 13 | 48,694,375 - 48,704,684 (+) | NCBI | Rnor_SHRSP | UTH_Rnor_SHRSP_BbbUtx_1.0 | | | | UTH_Rnor_WKY_Bbb_1.0 | 13 | 45,952,438 - 45,963,417 (+) | NCBI | Rnor_WKY | UTH_Rnor_WKY_Bbb_1.0 | | | | Rnor_6.0 | 13 | 50,502,724 - 50,513,953 (-) | NCBI | Rnor6.0 | Rnor_6.0 | rn6 | Rnor6.0 | | Rnor_6.0 Ensembl | 13 | 50,502,724 - 50,514,151 (-) | Ensembl | Rnor6.0 | | rn6 | Rnor6.0 | | Rnor_5.0 | 13 | 55,555,583 - 55,566,812 (-) | NCBI | Rnor5.0 | Rnor_5.0 | rn5 | Rnor5.0 | | RGSC_v3.4 | 13 | 46,262,936 - 46,275,213 (+) | NCBI | RGSC3.4 | RGSC_v3.4 | rn4 | RGSC3.4 | | RGSC_v3.1 | 13 | 46,277,000 - 46,288,249 (+) | NCBI | | | | | | Celera | 13 | 45,129,122 - 45,139,889 (+) | NCBI | | Celera | | | | RH 3.4 Map | 13 | 170.9 | RGD | | | | | | Cytogenetic Map | 13 | q13 | NCBI | | | | |
|
Ren
(Chinchilla lanigera - long-tailed chinchilla) |
| Chinchilla Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| ChiLan1.0 Ensembl | NW_004955406 | 40,016,630 - 40,026,286 (-) | Ensembl | ChiLan1.0 | | | | | ChiLan1.0 | NW_004955406 | 40,016,624 - 40,026,286 (-) | NCBI | ChiLan1.0 | ChiLan1.0 | | |
|
REN
(Pan paniscus - bonobo/pygmy chimpanzee) |
| Bonobo Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| NHGRI_mPanPan1-v2 | 1 | 45,210,086 - 45,221,659 (+) | NCBI | | NHGRI_mPanPan1-v2 | | | | NHGRI_mPanPan1 | 1 | 45,175,312 - 45,186,915 (+) | NCBI | | NHGRI_mPanPan1 | | | | Mhudiblu_PPA_v0 | 1 | 179,757,653 - 179,769,530 (-) | NCBI | Mhudiblu_PPA_v0 | Mhudiblu_PPA_v0 | panPan3 | | | PanPan1.1 | 1 | 184,045,917 - 184,057,431 (-) | NCBI | panpan1.1 | PanPan1.1 | panPan2 | | | PanPan1.1 Ensembl | 1 | 184,046,117 - 184,057,393 (-) | Ensembl | panpan1.1 | | panPan2 | |
|
REN
(Canis lupus familiaris - dog) |
| Dog Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| CanFam3.1 | 38 | 744,540 - 766,998 (-) | NCBI | CanFam3.1 | CanFam3.1 | canFam3 | CanFam3.1 | | CanFam3.1 Ensembl | 38 | 744,614 - 755,012 (-) | Ensembl | CanFam3.1 | | canFam3 | CanFam3.1 | | Dog10K_Boxer_Tasha | 38 | 840,126 - 850,501 (-) | NCBI | | Dog10K_Boxer_Tasha | | | | ROS_Cfam_1.0 | 38 | 740,693 - 762,325 (-) | NCBI | | ROS_Cfam_1.0 | | | | ROS_Cfam_1.0 Ensembl | 38 | 740,767 - 751,204 (-) | Ensembl | | ROS_Cfam_1.0 Ensembl | | | | UMICH_Zoey_3.1 | 38 | 736,523 - 746,891 (-) | NCBI | | UMICH_Zoey_3.1 | | | | UNSW_CanFamBas_1.0 | 38 | 1,127,902 - 1,138,260 (-) | NCBI | | UNSW_CanFamBas_1.0 | | | | UU_Cfam_GSD_1.0 | 38 | 1,328,102 - 1,338,487 (-) | NCBI | | UU_Cfam_GSD_1.0 | | |
|
Ren
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
|
REN
(Chlorocebus sabaeus - green monkey) |
| Green Monkey Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| ChlSab1.1 | 25 | 25,159,816 - 25,193,620 (+) | NCBI | ChlSab1.1 | ChlSab1.1 | chlSab2 | | | ChlSab1.1 Ensembl | 25 | 25,183,037 - 25,193,420 (+) | Ensembl | ChlSab1.1 | ChlSab1.1 Ensembl | chlSab2 | | | Vero_WHO_p1.0 | NW_023666055 | 25,943,204 - 25,954,169 (+) | NCBI | Vero_WHO_p1.0 | Vero_WHO_p1.0 | | |
|
Ren
(Heterocephalus glaber - naked mole-rat) |
|
.
| Ensembl Acc Id: |
ENSSSCT00000043605 ⟹ ENSSSCP00000045910 |
| Type: |
CODING |
| Position: |
| Pig Assembly | Chr | Position (strand) | Source |
|---|
| Sscrofa11.1 Ensembl | 9 | 64,809,146 - 64,822,636 (-) | Ensembl |
|
| Ensembl Acc Id: |
ENSSSCT00000053358 ⟹ ENSSSCP00000049573 |
| Type: |
CODING |
| Position: |
| Pig Assembly | Chr | Position (strand) | Source |
|---|
| Sscrofa11.1 Ensembl | 9 | 64,809,146 - 64,822,658 (-) | Ensembl |
|
| Ensembl Acc Id: |
ENSSSCT00000090617 ⟹ ENSSSCP00000059766 |
| Type: |
CODING |
| Position: |
| Pig Assembly | Chr | Position (strand) | Source |
|---|
| Sscrofa11.1 Ensembl | 9 | 64,809,146 - 64,818,619 (-) | Ensembl |
|
| RefSeq Acc Id: |
XM_021063211 ⟹ XP_020918870 |
| Type: |
CODING |
| Position: |
| Pig Assembly | Chr | Position (strand) | Source |
|---|
| Sscrofa11.1 | 9 | 64,809,143 - 64,822,605 (-) | NCBI |
|
| Sequence: |
AAGGGATCTTCATCGGATCCCAGGAAGGGCTGGGGACCCAGGTGGAGCATGGACCGGTGGAGCAGCATGCCGTGCTGGGGACTCCTGCTGGTGCTTTGGGGCTCCTGCACCTTCGGTCTCCCTGCAGA
CACTGGCGCCTTCAGTCGGATCTTCCTCAAGAAAATGCCCTCAGTCCGGGAAAGCCTGAAGGAGCGAGGCGTGGACATGGCCAGGCTGGGTGCTGAGTGGAGCCAGTTCAGCAAGAGACTCTCCTTTG
GCAACAGAACCAGCCCCGTGGTCCTCACCAACTACCTGGATACCCAGTACTATGGCGAGATCGGCATTGGCACCCCGCCACAGACCTTCAAAGTCATCTTCGACACAGGCTCGGCCAACCTCTGGGTG
CCCTCCACCAAATGCAGCCCTCTCTACACGGCCTGTGAGATTCACAGCCTCTACGACTCCTCGGAATCCTCCAGCTATGTGGAAAACGGGACGGAATTCACCATCCACTATGGGTCCGGGAAGGTCAA
AGGCTTCCTGAGCCAGGACCTAGTGACTGTGGGCGGATTCACAGTCACACAGACGTTTGGAGAGGTCACAGAGCTGCCCCTGATCCCCTTCATGCTGGCCAAGTTCGATGGTGTTCTGGGCATGGGCT
TCCCTGCACAGGCCGTCGGCGGGGTCACCCCCGTCTTTGACCACATCCTTTCCCAGAAGGTGCTGAAGGAGGACGTTTTCTCCGTCTACTACAGCAGAAATTCCAAGAATTCCCAGTTGCTGGGGGGA
GAGATTGTGCTGGGCGGCAGTGACCCCCAGTATTACCAGGACAGTTTCCACTACGTGAGCATCAGCAAGACTGGCTCCTGGCAGATCAAAATGAAAGGGGTGTCTGTGAGGTCGGCCACCTTGCTCTG
TGAGGAGGGCTGCATGGTGGTAGTGGATACCGGGGCATCCTACATCTCAGGTCCCACTAGCTCCCTGAGGCTGCTCATGGAGACCCTGGGGGCCAAGGAGCTGAGCACAGATGAATATGTTGTGAACT
GTAACCAAGTGCCCACACTCCCCGACATCTCCTTCCATCTCGGAGGCAGAGCCTACACGCTCACCAGTGCGGACTACGTCTTACAGGACCCCTACAATAACGATGATCTGTGCACACTGGCCCTCCAC
GGTCTGGACGTTCCACCGCCCACTGGACCCGTCTGGGTCCTTGGTGCCAGCTTCATCCGAAAGTTCTACACGGAGTTTGATCGACGTAACAATCGCATTGGCTTTGCCCTGGCCCGCTGAGGCCCACT
GCTGCCTTGCAGGCCCTGCGCTCGGCCCTAGCCCAGAGCTACATCACTCTCTGTGACCCATCCCCACCCTGCCTATGCTTGTGTCCTTACTCAGGGGCACAGGGCTTGGAGCACCTCCTGGATGTGTG
TCCTGCCCCCAGCATCGGCTCTTCCTGCTTTGAGGACAAATAAAAACTTCATGTTCACA
hide sequence
|
| RefSeq Acc Id: |
XM_021063212 ⟹ XP_020918871 |
| Type: |
CODING |
| Position: |
| Pig Assembly | Chr | Position (strand) | Source |
|---|
| Sscrofa11.1 | 9 | 64,809,338 - 64,822,604 (-) | NCBI |
|
| Sequence: |
AGGGATCTTCATCGGATCCCAGGAAGGGCTGGGGACCCAGGTGGAGCATGGACCGGTGGAGCAG
CATGCCGTGCTGGGGACTCCTGCTGGTGCTTTGGGGCTCCTGCACCTTCGGTCTCCCTGCAGACACTGGCGCCTTCAGTCGGATCTTCCTCAAGAAAATGCCCTCAGTCCGGGAAAGCCTGAAGGAGC
GAGGCGTGGACATGGCCAGGCTGGGTGCTGAGTGGAGCCAGTTCAGCAAGAGACTCTCCTTTGGCAACAGAACCAGCCCCGTGGTCCTCACCAACTACCTGGATACCCAGTACTATGGCGAGATCGGC
ATTGGCACCCCGCCACAGACCTTCAAAGTCATCTTCGACACAGGCTCGGCCAACCTCTGGGTGCCCTCCACCAAATGCAGCCCTCTCTACACGGCCTGTGAGATTCACAGCCTCTACGACTCCTCGGA
ATCCTCCAGCTATGTGGAAAACGGGACGGAATTCACCATCCACTATGGGTCCGGGAAGGTCAAAGGCTTCCTGAGCCAGGACCTAGTGACTGTGGGCGGATTCACAGTCACACAGACGTTTGGAGAGG
TCACAGAGCTGCCCCTGATCCCCTTCATGCTGGCCAAGTTCGATGGTGTTCTGGGCATGGGCTTCCCTGCACAGGCCGTCGGCGGGGTCACCCCCGTCTTTGACCACATCCTTTCCCAGAAGGTGCTG
AAGGAGGACGTTTTCTCCGTCTACTACAGCAGGAATTCCCAGTTGCTGGGGGGAGAGATTGTGCTGGGCGGCAGTGACCCCCAGTATTACCAGGACAGTTTCCACTACGTGAGCATCAGCAAGACTGG
CTCCTGGCAGATCAAAATGAAAGGGGTGTCTGTGAGGTCGGCCACCTTGCTCTGTGAGGAGGGCTGCATGGTGGTAGTGGATACCGGGGCATCCTACATCTCAGGTCCCACTAGCTCCCTGAGGCTGC
TCATGGAGACCCTGGGGGCCAAGGAGCTGAGCACAGATGAATATGTTGTGAACTGTAACCAAGTGCCCACACTCCCCGACATCTCCTTCCATCTCGGAGGCAGAGCCTACACGCTCACCAGTGCGGAC
TACGTCTTACAGGACCCCTACAATAACGATGATCTGTGCACACTGGCCCTCCACGGTCTGGACGTTCCACCGCCCACTGGACCCGTCTGGGTCCTTGGTGCCAGCTTCATCCGAAAGTTCTACACGGA
GTTTGATCGACGTAACAATCGCATTGGCTTTGCCCTGGCCCGCTGA
hide sequence
|
| RefSeq Acc Id: |
XP_020918870 ⟸ XM_021063211 |
| - Peptide Label: |
isoform X1 |
| - UniProtKB: |
A0A4X1V377 (UniProtKB/TrEMBL), A0A287B096 (UniProtKB/TrEMBL), A0A287APG1 (UniProtKB/TrEMBL), A0A8D1TQZ6 (UniProtKB/TrEMBL) |
| - Sequence: |
MDRWSSMPCWGLLLVLWGSCTFGLPADTGAFSRIFLKKMPSVRESLKERGVDMARLGAEWSQFSKRLSFGNRTSPVVLTNYLDTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSPLYTACEIHS
LYDSSESSSYVENGTEFTIHYGSGKVKGFLSQDLVTVGGFTVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQKVLKEDVFSVYYSRNSKNSQLLGGEIVLGGSDPQYYQDSF
HYVSISKTGSWQIKMKGVSVRSATLLCEEGCMVVVDTGASYISGPTSSLRLLMETLGAKELSTDEYVVNCNQVPTLPDISFHLGGRAYTLTSADYVLQDPYNNDDLCTLALHGLDVPPPTGPVWVLGA
SFIRKFYTEFDRRNNRIGFALAR
hide sequence
|
|
| RefSeq Acc Id: |
XP_020918871 ⟸ XM_021063212 |
| - Peptide Label: |
isoform X2 |
| - UniProtKB: |
A0A4X1UXZ7 (UniProtKB/TrEMBL), A0A8D1TQZ6 (UniProtKB/TrEMBL) |
| - Sequence: |
MDRWSSMPCWGLLLVLWGSCTFGLPADTGAFSRIFLKKMPSVRESLKERGVDMARLGAEWSQFS
KRLSFGNRTSPVVLTNYLDTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSPLYTACEIHSLYDSSESSSYVENGTEFTIHYGSGKVKGFLSQDLVTVGGFTVTQTFGEVTELPLIPFMLAKFDG
VLGMGFPAQAVGGVTPVFDHILSQKVLKEDVFSVYYSRNSQLLGGEIVLGGSDPQYYQDSFHYVSISKTGSWQIKMKGVSVRSATLLCEEGCMVVVDTGASYISGPTSSLRLLMETLGAKELSTDEYV
VNCNQVPTLPDISFHLGGRAYTLTSADYVLQDPYNNDDLCTLALHGLDVPPPTGPVWVLGASFIRKFYTEFDRRNNRIGFALAR
hide sequence
|
|
| Ensembl Acc Id: |
ENSSSCP00000059766 ⟸ ENSSSCT00000090617 |
|
| Ensembl Acc Id: |
ENSSSCP00000045910 ⟸ ENSSSCT00000043605 |
|
| Ensembl Acc Id: |
ENSSSCP00000049573 ⟸ ENSSSCT00000053358 |
|
|
|
