GLRX (glutaredoxin) - Rat Genome Database

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Gene: GLRX (glutaredoxin) Sus scrofa
Analyze
Symbol: GLRX
Name: glutaredoxin
RGD ID: 13988887
Description: ENCODES a protein that exhibits glutathione disulfide oxidoreductase activity (ortholog); protein N-terminus binding (ortholog); INVOLVED IN aging (ortholog); cellular response to estradiol stimulus (ortholog); cellular response to glucose stimulus (ortholog); ASSOCIATED WITH COVID-19 (ortholog); Experimental Diabetes Mellitus (ortholog); familial adenomatous polyposis 1 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); dendrite (ortholog); INTERACTS WITH 3-oxalomalic acid; cadmium atom; cadmium dichloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GLRX1; glutaredoxin-1; GRX1; thioltransferase; thioltransferase-1; TTase-1; TTF
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.12102,425,580 - 102,437,851 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22106,309,433 - 106,321,705 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:2583530   PMID:3571278   PMID:3571279   PMID:8535236   PMID:14681463   PMID:17681533   PMID:25227108  


Genomics

Comparative Map Data
GLRX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.12102,425,580 - 102,437,851 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22106,309,433 - 106,321,705 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GLRX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl595,751,319 - 95,822,726 (-)EnsemblGRCh38hg38GRCh38
GRCh38595,813,849 - 95,822,726 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37595,149,553 - 95,158,430 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36595,175,431 - 95,184,137 (-)NCBINCBI36hg18NCBI36
Build 34595,175,430 - 95,184,137NCBI
Celera591,028,293 - 91,037,329 (-)NCBI
Cytogenetic Map5q15NCBI
HuRef590,339,863 - 90,348,899 (-)NCBIHuRef
CHM1_1594,582,332 - 94,591,368 (-)NCBICHM1_1
Glrx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391375,988,004 - 75,998,270 (+)NCBIGRCm39mm39
GRCm39 Ensembl1375,987,987 - 75,998,273 (+)Ensembl
GRCm381375,839,885 - 75,850,151 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1375,839,868 - 75,850,154 (+)EnsemblGRCm38mm10GRCm38
MGSCv371375,977,334 - 75,987,599 (+)NCBIGRCm37mm9NCBIm37
MGSCv361376,305,914 - 76,316,151 (+)NCBImm8
Celera1378,161,342 - 78,171,745 (+)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.95NCBI
Glrx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.225,341,873 - 5,351,686 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl25,341,885 - 5,351,680 (+)Ensembl
Rnor_6.022,606,032 - 2,615,944 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl22,605,996 - 2,615,944 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.022,604,479 - 2,614,391 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.422,888,605 - 2,899,216 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.122,908,046 - 2,918,657 (+)NCBI
Celera21,812,028 - 1,821,780 (+)NCBICelera
Cytogenetic Map2q11NCBI
Glrx
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541816,747,776 - 16,752,858 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541816,747,709 - 16,754,718 (+)NCBIChiLan1.0ChiLan1.0
GLRX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1519,671,833 - 19,680,685 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl519,671,965 - 19,680,685 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0519,526,210 - 19,535,237 (+)NCBIMhudiblu_PPA_v0panPan3
GLRX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1313,795,609 - 13,804,732 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl313,795,817 - 13,803,895 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha315,134,941 - 15,144,033 (+)NCBI
ROS_Cfam_1.0313,675,696 - 13,684,691 (+)NCBI
UMICH_Zoey_3.1313,638,543 - 13,647,633 (+)NCBI
UNSW_CanFamBas_1.0313,635,534 - 13,644,630 (+)NCBI
UU_Cfam_GSD_1.0313,835,410 - 13,844,529 (+)NCBI
Glrx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213169,350,320 - 169,358,900 (+)NCBI
SpeTri2.0NW_0049365237,535,650 - 7,544,339 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GLRX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1489,687,354 - 89,696,236 (-)NCBI
ChlSab1.1 Ensembl489,685,984 - 89,696,231 (-)Ensembl
Vero_WHO_p1.0NW_02366604938,333,100 - 38,342,156 (-)NCBI
Glrx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474314,443,394 - 14,451,561 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 8 2 5 2 2 1 3
Low 2 2 3 2 21 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_214233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005654989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK230519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK391305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK391550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY550049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU462919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01018626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB874325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB874880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB881236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB882383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB890982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB892806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB894104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB895454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB903285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC931734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC932289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC938645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC939792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC948391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC950215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC951513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC952863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC960694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ658473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ670734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M31453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: NM_214233   ⟹   NP_999398
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12102,426,648 - 102,437,761 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005654989   ⟹   XP_005655046
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12102,425,580 - 102,437,851 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005655046   ⟸   XM_005654989
- Peptide Label: isoform X1
- UniProtKB: P12309 (UniProtKB/Swiss-Prot),   F2XWZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_999398   ⟸   NM_214233
- UniProtKB: P12309 (UniProtKB/Swiss-Prot),   F2XWZ9 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Glutaredoxin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000039731 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSSSCG00015031581 UniProtKB/Swiss-Prot
  ENSSSCG00025008850 UniProtKB/Swiss-Prot
  ENSSSCG00030008733 UniProtKB/Swiss-Prot
  ENSSSCG00035048008 UniProtKB/Swiss-Prot
  ENSSSCG00040011271 UniProtKB/Swiss-Prot
  ENSSSCG00050073370 UniProtKB/Swiss-Prot
  ENSSSCG00055008895 UniProtKB/Swiss-Prot
  ENSSSCG00060025386 UniProtKB/Swiss-Prot
  ENSSSCG00065012614 UniProtKB/Swiss-Prot
  ENSSSCG00070009533 UniProtKB/Swiss-Prot
Ensembl Protein ENSSSCP00000059302 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSSSCP00015016629 UniProtKB/Swiss-Prot
  ENSSSCP00025004706 UniProtKB/Swiss-Prot
  ENSSSCP00030005351 UniProtKB/Swiss-Prot
  ENSSSCP00035025886 UniProtKB/Swiss-Prot
  ENSSSCP00040005769 UniProtKB/Swiss-Prot
  ENSSSCP00050043495 UniProtKB/Swiss-Prot
  ENSSSCP00055013744 UniProtKB/Swiss-Prot
  ENSSSCP00060014750 UniProtKB/Swiss-Prot
  ENSSSCP00065006872 UniProtKB/Swiss-Prot
  ENSSSCP00065006878 UniProtKB/Swiss-Prot
  ENSSSCP00070015369 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000051052 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSSSCT00015042086 UniProtKB/Swiss-Prot
  ENSSSCT00025011805 UniProtKB/Swiss-Prot
  ENSSSCT00030011918 UniProtKB/Swiss-Prot
  ENSSSCT00035063938 UniProtKB/Swiss-Prot
  ENSSSCT00040014777 UniProtKB/Swiss-Prot
  ENSSSCT00050100287 UniProtKB/Swiss-Prot
  ENSSSCT00055017383 UniProtKB/Swiss-Prot
  ENSSSCT00060034428 UniProtKB/Swiss-Prot
  ENSSSCT00065016810 UniProtKB/Swiss-Prot
  ENSSSCT00065016819 UniProtKB/Swiss-Prot
  ENSSSCT00070018496 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.30.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GLR_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutaredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutaredoxin_euk/vir UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutaredoxin_subgr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397463 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene GLRX ENTREZGENE
Pfam Glutaredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS GLUTAREDOXIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GLUTAREDOXIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLUTAREDOXIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs GRX_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt F2XWZ9 ENTREZGENE, UniProtKB/TrEMBL
  GLRX1_PIG UniProtKB/Swiss-Prot, ENTREZGENE