AK1 (adenylate kinase 1) - Rat Genome Database

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Gene: AK1 (adenylate kinase 1) Sus scrofa
Analyze
Symbol: AK1
Name: adenylate kinase 1
RGD ID: 14028643
Description: ENCODES a protein that exhibits adenylate kinase activity; nucleoside diphosphate kinase activity (ortholog); phosphotransferase activity, phosphate group as acceptor (ortholog); INVOLVED IN ADP biosynthetic process (ortholog); AMP metabolic process (ortholog); cerebellum development (ortholog); PARTICIPATES IN adefovir pharmacokinetics pathway; adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; ASSOCIATED WITH congenital disorder of glycosylation Iu (ortholog); congenital nonspherocytic hemolytic anemia (ortholog); Congenital Nonspherocytic Hemolytic Anemia 3 (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog); sarcomere (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Adenylate kinase isoenzyme 1; Adenylate monophosphate kinase; AK 1; ATP-AMP transphosphorylase 1; ATP:AMP phosphotransferase; Myokinase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,355,033 - 268,365,598 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11268,355,032 - 268,365,659 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,278,352 - 302,287,965 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:2551297   PMID:2832612   PMID:2869483   PMID:4366177   PMID:4367210   PMID:15679890   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
AK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,355,033 - 268,365,598 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11268,355,032 - 268,365,659 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,278,352 - 302,287,965 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389127,866,480 - 127,879,621 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9127,866,486 - 127,877,675 (-)EnsemblGRCh38hg38GRCh38
GRCh379130,628,759 - 130,641,900 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,668,580 - 129,679,843 (-)NCBINCBI36Build 36hg18NCBI36
Build 349127,708,222 - 127,719,495NCBI
Celera9101,279,601 - 101,290,850 (-)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9100,246,223 - 100,257,472 (-)NCBIHuRef
CHM1_19130,780,691 - 130,791,941 (-)NCBICHM1_1
T2T-CHM13v2.09140,073,895 - 140,087,021 (-)NCBIT2T-CHM13v2.0
Ak1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,511,770 - 32,525,070 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,511,770 - 32,525,070 (+)EnsemblGRCm39 Ensembl
GRCm38232,621,758 - 32,635,058 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,621,758 - 32,635,058 (+)EnsemblGRCm38mm10GRCm38
MGSCv37232,485,024 - 32,490,572 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36232,451,513 - 32,457,061 (+)NCBIMGSCv36mm8
Celera232,336,146 - 32,341,694 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
Ak1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,310,113 - 36,320,760 (+)NCBIGRCr8
mRatBN7.2315,912,431 - 15,923,045 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl315,912,485 - 15,923,041 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx318,984,611 - 18,991,850 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0327,569,617 - 27,576,860 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,820,734 - 25,827,945 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0311,652,143 - 11,659,135 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0316,995,977 - 17,002,969 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4219,821,482 - 19,822,544 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1219,741,850 - 19,742,913 (+)NCBI
Celera310,656,923 - 10,664,139 (+)NCBICelera
Cytogenetic Map3p11NCBI
Ak1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955419799,410 - 811,029 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955419799,415 - 807,138 (+)NCBIChiLan1.0ChiLan1.0
AK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,476,471 - 11,486,406 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1911,478,853 - 11,488,753 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0998,987,348 - 98,997,252 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19127,657,338 - 127,678,245 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9127,657,338 - 127,678,245 (-)Ensemblpanpan1.1panPan2
AK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1955,539,179 - 55,548,132 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl955,539,260 - 55,548,132 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,737,172 - 54,742,120 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0956,461,156 - 56,477,699 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl956,461,226 - 56,470,095 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1955,225,113 - 55,230,060 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0955,539,847 - 55,544,794 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0955,631,318 - 55,636,272 (+)NCBIUU_Cfam_GSD_1.0
Ak1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947195,739,140 - 195,748,925 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648715,507,498 - 15,517,469 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648715,507,663 - 15,517,401 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11210,251,793 - 10,261,635 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1210,256,054 - 10,261,465 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660795,960,893 - 5,972,066 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ak1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247607,684,109 - 7,693,405 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247607,684,098 - 7,693,051 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in AK1
491 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 5 14 12 23 3 6 1

Sequence


Ensembl Acc Id: ENSSSCT00000006187   ⟹   ENSSSCP00000006028
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1268,355,033 - 268,365,598 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000054545   ⟹   ENSSSCP00000033755
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1268,356,054 - 268,360,974 (-)Ensembl
RefSeq Acc Id: XM_003122177   ⟹   XP_003122225
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11268,355,032 - 268,365,659 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005660452   ⟹   XP_005660509
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11268,355,032 - 268,365,601 (-)NCBI
Sequence:
RefSeq Acc Id: XP_003122225   ⟸   XM_003122177
- UniProtKB: P00571 (UniProtKB/Swiss-Prot),   A0A480SN78 (UniProtKB/TrEMBL),   A0A5S6G079 (UniProtKB/TrEMBL),   A0A8D1SP70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005660509   ⟸   XM_005660452
- UniProtKB: P00571 (UniProtKB/Swiss-Prot),   A0A480SN78 (UniProtKB/TrEMBL),   A0A5S6G079 (UniProtKB/TrEMBL),   A0A8D1SP70 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000033755   ⟸   ENSSSCT00000054545
Ensembl Acc Id: ENSSSCP00000006028   ⟸   ENSSSCT00000006187


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000005627 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00015060480 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00025045130 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00030073169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00035023319 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00045008653 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00050013292 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00055017917 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00060004865 UniProtKB/TrEMBL
  ENSSSCG00065075808 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00070014422 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000006187 ENTREZGENE
  ENSSSCT00000006187.3 UniProtKB/TrEMBL
  ENSSSCT00000006187.4 UniProtKB/Swiss-Prot
  ENSSSCT00000054545 ENTREZGENE
  ENSSSCT00000054545.3 UniProtKB/TrEMBL
  ENSSSCT00015081508.1 UniProtKB/Swiss-Prot
  ENSSSCT00015082072.1 UniProtKB/TrEMBL
  ENSSSCT00025061292.1 UniProtKB/Swiss-Prot
  ENSSSCT00025061489.1 UniProtKB/TrEMBL
  ENSSSCT00025061596.1 UniProtKB/TrEMBL
  ENSSSCT00025061662.1 UniProtKB/TrEMBL
  ENSSSCT00030102473.1 UniProtKB/Swiss-Prot
  ENSSSCT00030102490.1 UniProtKB/TrEMBL
  ENSSSCT00030102518.1 UniProtKB/TrEMBL
  ENSSSCT00035030554.1 UniProtKB/Swiss-Prot
  ENSSSCT00035030559.1 UniProtKB/TrEMBL
  ENSSSCT00035030569.1 UniProtKB/TrEMBL
  ENSSSCT00045014609.1 UniProtKB/Swiss-Prot
  ENSSSCT00045014676.1 UniProtKB/TrEMBL
  ENSSSCT00045014725.1 UniProtKB/TrEMBL
  ENSSSCT00045014758.1 UniProtKB/TrEMBL
  ENSSSCT00050017947.1 UniProtKB/Swiss-Prot
  ENSSSCT00050017974.1 UniProtKB/TrEMBL
  ENSSSCT00050018014.1 UniProtKB/TrEMBL
  ENSSSCT00055035609.1 UniProtKB/TrEMBL
  ENSSSCT00055035787.1 UniProtKB/TrEMBL
  ENSSSCT00055035865.1 UniProtKB/Swiss-Prot
  ENSSSCT00055035936.1 UniProtKB/Swiss-Prot
  ENSSSCT00055035994.1 UniProtKB/Swiss-Prot
  ENSSSCT00055036248.1 UniProtKB/TrEMBL
  ENSSSCT00060006042.1 UniProtKB/TrEMBL
  ENSSSCT00065104781.1 UniProtKB/Swiss-Prot
  ENSSSCT00065104797.1 UniProtKB/TrEMBL
  ENSSSCT00070028311.1 UniProtKB/TrEMBL
  ENSSSCT00070028319.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.1480.20 UniProtKB/TrEMBL
InterPro Adenylat/UMP-CMP_kin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Adenylat_kinase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AK1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AK1/5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_trans_29 UniProtKB/TrEMBL
  GT29-like_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:100521423 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene AK1 ENTREZGENE
PANTHER ADENYLATE KINASE ISOENZYME 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 6 UniProtKB/TrEMBL
  PTHR23359 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45906 UniProtKB/TrEMBL
Pfam ADK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_transf_29 UniProtKB/TrEMBL
PRINTS ADENYLTKNASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ADENYLATE_KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A286ZQ79_PIG UniProtKB/TrEMBL
  A0A480SN78 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U437_PIG UniProtKB/TrEMBL
  A0A4X1U678_PIG UniProtKB/TrEMBL
  A0A5S6G079 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0PKG1_PIG UniProtKB/TrEMBL
  A0A8D0S3P1_PIG UniProtKB/TrEMBL
  A0A8D0S5D1_PIG UniProtKB/TrEMBL
  A0A8D0Y7C8_PIG UniProtKB/TrEMBL
  A0A8D1R1S2_PIG UniProtKB/TrEMBL
  A0A8D1R3E4_PIG UniProtKB/TrEMBL
  A0A8D1SP70 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D2AA01_PIG UniProtKB/TrEMBL
  KAD1_PIG UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:97875 ENTREZGENE