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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
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Accession:GO:0051897 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction.
Synonyms:exact_synonym: positive regulation of PI3K-PKB/Akt pathway;   positive regulation of PI3K/Akt signal transduction;   positive regulation of PI3K/PKB signal transduction;   positive regulation of phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction
 narrow_synonym: activation of protein kinase B signaling cascade;   stimulation of protein kinase B signaling cascade
 related_synonym: positive regulation of AKT signaling cascade;   positive regulation of AKT signalling cascade;   positive regulation of PKB signaling cascade;   positive regulation of PKB signalling cascade;   positive regulation of protein kinase B signaling;   positive regulation of protein kinase B signaling cascade;   positive regulation of protein kinase B signalling cascade;   up regulation of protein kinase B signaling cascade;   upregulation of protein kinase B signaling cascade


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positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 ADAM metallopeptidase domain 8 involved_in ISO (MGI:5009349|PMID:20683884) RGD PMID:20683884 MGI:5009349 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801 		JBrowse link
G Adora3 adenosine A3 receptor acts_upstream_of_or_within ISO (PMID:12817016) RGD PMID:12817016 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357 		JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 involved_in IMP PMID:14528310
PMID:18469807		 UniProt PMID:14528310 PMID:18469807 RGD:1299350, RGD:8553892 NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295 		JBrowse link
G Agt angiotensinogen involved_in ISO
IEA		 (PMID:15652490)
GO_REF:0000107		 RGD
Ensembl		 PMID:15652490 GO_REF:0000107 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 involved_in ISO (PMID:18508192) RGD PMID:18508192 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:18508192) RGD PMID:18508192 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 involved_in ISO (PMID:21753002) RGD PMID:21753002 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221 		JBrowse link
G Angpt1 angiopoietin 1 involved_in
acts_upstream_of_or_within_positive_effect		 IEA
ISO		 GO_REF:0000107
(PMID:19615361)
(PMID:18425120)
(PMID:19409199)		 Ensembl
RGD		 PMID:18425120 PMID:19409199 PMID:19615361 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Arfgef1 ADP ribosylation factor guanine nucleotide exchange factor 1 involved_in IMP PMID:24090963 CACAO PMID:24090963 RGD:10047159 NCBI chr 5:8,982,061...9,076,326
Ensembl chr 5:8,981,540...9,076,326 		JBrowse link
G Arrb2 arrestin, beta 2 involved_in IMP
ISO
IEA		 (MGI:3690676|PMID:16051150)
GO_REF:0000107		 RGD
Ensembl		 PMID:16051150 PMID:19171933 GO_REF:0000107 MGI:3690676, RGD:5510006 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Axl Axl receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 ISO
IBA		 (MGI:5315346|PMID:16723520)
GO_REF:0000033
MGI:2387750|MGI:95660 (PMID:15650770), (PMID:16627783)		 RGD
GO_Central		 PMID:15650770 PMID:16627783 PMID:16723520 GO_REF:0000033 MGI:5315346 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G Bag4 BAG cochaperone 4 involved_in ISO (MGI:5292318|PMID:21712384) RGD PMID:21712384 MGI:5292318 NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663 		JBrowse link
G C1qbp complement C1q binding protein involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:16177118)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:16177118 GO_REF:0000024 GO_REF:0000107 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649 		JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18783346)		 Ensembl
RGD		 PMID:18783346 GO_REF:0000107 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660 		JBrowse link
G C1qtnf12 C1q and TNF related 12 acts_upstream_of_or_within ISO (PMID:22275362) RGD PMID:22275362 NCBI chr 5:166,551,628...166,556,003
Ensembl chr 5:166,551,628...166,556,003 		JBrowse link
G C1qtnf3 C1q and TNF related 3 acts_upstream_of_or_within ISO (PMID:20952387) RGD PMID:20952387 NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433 		JBrowse link
G Calcr calcitonin receptor involved_in ISO
IEA		 UniProtKB:O60896|UniProtKB:P10997-PRO_0000004106 (PMID:22500019)
GO_REF:0000107		 RGD
Ensembl		 PMID:22500019 GO_REF:0000107 NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392 		JBrowse link
G Cass4 Cas scaffold protein family member 4 involved_in ISO (PMID:27677288) RGD PMID:27677288 NCBI chr 3:161,162,520...161,202,523
Ensembl chr 3:161,163,436...161,202,186 		JBrowse link
G Cat catalase acts_upstream_of_or_within ISO (PMID:15020231) RGD PMID:15020231 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cbl Cbl proto-oncogene involved_in ISO (PMID:17003487) RGD PMID:17003487 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176 		JBrowse link
G Ccdc88a coiled coil domain containing 88A involved_in ISO (MGI:3581096|PMID:15753085) RGD PMID:15753085 MGI:3581096 NCBI chr14:103,104,091...103,256,112
Ensembl chr14:103,103,513...103,252,368 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:15059845), (PMID:15778365) RGD PMID:15059845 PMID:15778365 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl21 C-C motif chemokine ligand 21 involved_in ISO (PMID:15059845), (PMID:15778365) RGD PMID:15059845 PMID:15778365 NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 involved_in ISO (PMID:21403648) RGD PMID:21403648 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 involved_in ISO
IDA		 (PMID:7544376)
PMID:10477596		 RGD PMID:7544376 PMID:10477596 RGD:8553666 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Cd19 CD19 molecule involved_in ISO (PMID:9382888)
(MGI:1100180|PMID:9382888)		 RGD PMID:9382888 MGI:1100180 NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975 		JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO (PMID:23589618) RGD PMID:23589618 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685 		JBrowse link
G Cdc42 cell division cycle 42 acts_upstream_of_or_within ISO (PMID:15728722) RGD PMID:15728722 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Chi3l1 chitinase 3 like 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:21385870)
(MGI:5306542|PMID:21546314)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:21385870 PMID:21546314 GO_REF:0000024 GO_REF:0000107 MGI:5306542 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787 		JBrowse link
G Cntf ciliary neurotrophic factor IDA RGD PMID:15574731 RGD:1626128 NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877 		JBrowse link
G Cpne1 copine 1 involved_in ISO
IEA		 (PMID:23263657), (PMID:25450385)
GO_REF:0000107		 RGD
Ensembl		 PMID:23263657 PMID:25450385 GO_REF:0000107 NCBI chr 3:144,587,531...144,629,911
Ensembl chr 3:144,588,995...144,598,636 		JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5294513|PMID:21610095)		 UniProt
Ensembl
RGD		 PMID:21610095 GO_REF:0000024 GO_REF:0000107 MGI:5294513 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO (PMID:24520418) RGD PMID:24520418 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csf3 colony stimulating factor 3 involved_in ISO (PMID:23001182) RGD PMID:23001182 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO
IMP		 UniProtKB:P35411 (PMID:10415068), (PMID:10869418)
PMID:12729461		 RGD PMID:10415068 PMID:10869418 PMID:12729461 RGD:13673777 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IGI PMID:10869418 ARUK-UCL PMID:10869418 RGD:4892026 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 acts_upstream_of_or_within ISO MGI:1341264 (PMID:22956548) RGD PMID:22956548 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Dcn decorin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23798385)
GO_REF:0000107		 RGD
Ensembl		 PMID:23798385 GO_REF:0000107 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Egf epidermal growth factor involved_in ISO
IEA		 UniProtKB:O00329 (PMID:31915155)
GO_REF:0000107		 RGD
Ensembl		 PMID:31915155 GO_REF:0000107 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:17655843) RGD PMID:17655843 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Eng endoglin involved_in ISO RNAcentral:URS00005A8080_9606 (PMID:26857067) RGD PMID:26857067 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Epha8 Eph receptor A8 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:5294313|PMID:11416136)		 Ensembl
UniProt
RGD		 PMID:11416136 GO_REF:0000024 GO_REF:0000107 MGI:5294313 NCBI chr 5:149,166,107...149,193,515
Ensembl chr 5:149,166,697...149,193,399 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 IMP RGD PMID:16168116 RGD:1582137 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:96083 (PMID:18458158)		 Ensembl
RGD		 PMID:18458158 GO_REF:0000107 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Erfe erythroferrone involved_in IMP
ISO		 PMID:30566056
(MGI:6447448|PMID:30566056)		 RGD PMID:30566056 PMID:30566056 MGI:6447448, RGD:329845503 NCBI chr 9:91,956,971...91,964,846
Ensembl chr 9:91,956,977...91,964,846 		JBrowse link
G Extl3 exostosin-like glycosyltransferase 3 involved_in ISO (PMID:22727489), (PMID:27830702) RGD PMID:22727489 PMID:27830702 NCBI chr15:39,294,033...39,384,086
Ensembl chr15:39,293,605...39,338,898 		JBrowse link
G F2 coagulation factor II, thrombin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:101780|MGI:101802 (PMID:18398001)		 Ensembl
RGD		 PMID:18398001 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 GO_REF:0000024
(MGI:5285163|PMID:20215560)
GO_REF:0000107
MGI:88380 (PMID:18398001)		 UniProt
RGD
Ensembl		 PMID:18398001 PMID:20215560 GO_REF:0000024 GO_REF:0000107 MGI:5285163 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5285163|PMID:20215560)		 UniProt
RGD		 PMID:20215560 GO_REF:0000024 MGI:5285163 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fam110c family with sequence similarity 110, member C involved_in ISO
ISS		 (PMID:19698782)
GO_REF:0000024		 RGD
UniProt		 PMID:19698782 GO_REF:0000024 NCBI chr 6:47,638,466...47,644,723
Ensembl chr 6:47,638,276...47,644,634 		JBrowse link
G Fer FER tyrosine kinase acts_upstream_of_positive_effect ISO (MGI:1928184|PMID:11006284) RGD PMID:11006284 MGI:1928184 NCBI chr 9:103,520,452...103,827,364
Ensembl chr 9:103,520,493...103,821,451 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in ISO (PMID:24226523) RGD PMID:24226523 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811 		JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in
acts_upstream_of_or_within		 ISO UniProtKB:O00329 (PMID:20011604), (PMID:26451614), (PMID:31915155)
(PMID:16858399)		 RGD PMID:16858399 PMID:20011604 PMID:26451614 PMID:31915155 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 involved_in ISO RNAcentral:URS000058BB84_9606|UniProtKB:P09038 (PMID:26451614) RGD PMID:26451614 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 involved_in ISO (PMID:11294897) RGD PMID:11294897 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:10739672) RGD PMID:10739672 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:11312102), (PMID:14633857)		 Ensembl
RGD		 PMID:11312102 PMID:14633857 GO_REF:0000107 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fn1 fibronectin 1 involved_in ISO
IEA		 (PMID:19126672)
GO_REF:0000107		 RGD
Ensembl		 PMID:19126672 GO_REF:0000107 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fshr follicle stimulating hormone receptor involved_in ISO
ISS		 (PMID:24058690)
GO_REF:0000024		 RGD
UniProt		 PMID:24058690 GO_REF:0000024 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gas6 growth arrest specific 6 involved_in
acts_upstream_of_or_within		 IDA
ISO		 PMID:18374201
(PMID:16359517), (PMID:16723520), (PMID:18680538), (PMID:20103767)
MGI:104294|MGI:1347244|MGI:2675495|MGI:96965 (PMID:15650770), (PMID:18188450)		 RGD PMID:15650770 PMID:16359517 PMID:16723520 PMID:18188450 PMID:18680538 More... RGD:8554638 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gata3 GATA binding protein 3 involved_in ISO (PMID:19674970) RGD PMID:19674970 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 involved_in ISO (PMID:21750175)
(MGI:5545971|PMID:21750175)		 RGD PMID:21750175 MGI:5545971 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611 		JBrowse link
G Gdf15 growth differentiation factor 15 involved_in ISO
ISS
IEA		 (PMID:28846097), (PMID:28846099)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:28846097 PMID:28846099 GO_REF:0000024 GO_REF:0000107 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gfral GDNF family receptor alpha like involved_in ISO
IEA		 (PMID:28846097)
GO_REF:0000107		 RGD
Ensembl		 PMID:28846097 GO_REF:0000107 NCBI chr 8:76,917,894...76,963,258
Ensembl chr 8:76,918,657...76,959,425 		JBrowse link
G Gh1 growth hormone 1 involved_in ISO (PMID:7782332) RGD PMID:7782332 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA
IMP
ISO
IEA		 (PMID:15705806)
GO_REF:0000107		 RGD
Ensembl		 PMID:15705806 PMID:19717735 PMID:19717735 GO_REF:0000107, RGD:4892081, RGD:4892081 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2158814 (PMID:15663476)		 Ensembl
RGD		 PMID:15663476 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 involved_in IMP PMID:28392297 ARUK-UCL PMID:28392297 RGD:21201273 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146 		JBrowse link
G Hax1 HCLS1 associated protein X-1 involved_in ISO (PMID:23001182) RGD PMID:23001182 NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor involved_in ISO (PMID:17655843) RGD PMID:17655843 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 involved_in ISO (PMID:23001182) RGD PMID:23001182 NCBI chr11:63,817,482...63,840,943
Ensembl chr11:63,817,476...63,841,014 		JBrowse link
G Hcst hematopoietic cell signal transducer involved_in ISO
IEA
IBA		 (PMID:10426994)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033		 RGD
Ensembl
InterPro
GO_Central		 PMID:10426994 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:85,676,976...85,679,083
Ensembl chr 1:85,676,979...85,679,012 		JBrowse link
G Hgf hepatocyte growth factor involved_in ISO
IEA		 (PMID:20655899)
GO_REF:0000107		 RGD
Ensembl		 PMID:20655899 GO_REF:0000107 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hnf1a HNF1 homeobox A IMP RGD PMID:21874357 RGD:150540304 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Hpse heparanase involved_in IEA
ISO		 GO_REF:0000107
(PMID:15044433)
(MGI:3721153|PMID:17689495)		 Ensembl
RGD		 PMID:15044433 PMID:17689495 GO_REF:0000107 MGI:3721153 NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010 		JBrowse link
G Iapp islet amyloid polypeptide involved_in ISO ComplexPortal:CPX-3187|UniProtKB:O60896|UniProtKB:P30988 (PMID:22500019) RGD PMID:22500019 NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in
acts_upstream_of_or_within		 ISO
IDA
IEA
IBA		 (PMID:24508636), (PMID:7688386), (PMID:7692086)
PMID:17023532
GO_REF:0000107
(PMID:19208758), (PMID:21413931)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:7688386 PMID:7692086 PMID:19208758 PMID:21413931 PMID:24508636 More... GO_REF:0000033 GO_REF:0000107, RGD:1600072 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor involved_in
acts_upstream_of_or_within		 IMP
ISO
IEA
IBA		 (PMID:7692086)
GO_REF:0000107
GO_REF:0000033
MGI:2386328 (PMID:18451178)		 RGD
Ensembl
GO_Central		 PMID:7692086 PMID:18451178 PMID:25186839 GO_REF:0000033 GO_REF:0000107, RGD:10046020 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igf2 insulin-like growth factor 2 involved_in ISO (PMID:11500939)
(MGI:4438697|PMID:20032056)		 RGD PMID:11500939 PMID:20032056 MGI:4438697 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 acts_upstream_of_or_within ISO (PMID:18762576) RGD PMID:18762576 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
G Il18 interleukin 18 involved_in ISO
IEA		 (PMID:21321938)
GO_REF:0000107		 RGD
Ensembl		 PMID:21321938 GO_REF:0000107 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il6 interleukin 6 IDA RGD PMID:20227492 RGD:5128677 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ilk integrin-linked kinase IMP RGD PMID:16941698 RGD:2302063 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Ins2 insulin 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:11500939), (PMID:25240198), (PMID:7688386)
GO_REF:0000107
(PMID:11375348)		 RGD
Ensembl		 PMID:7688386 PMID:11375348 PMID:11500939 PMID:25240198 GO_REF:0000107 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Insr insulin receptor involved_in ISO
IEA
IBA		 (PMID:11500939)
(MGI:4438697|PMID:20032056)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:11500939 PMID:20032056 GO_REF:0000033 GO_REF:0000107 MGI:4438697 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Irs1 insulin receptor substrate 1 involved_in
acts_upstream_of_or_within		 IDA
ISO		 PMID:1380456
(PMID:11375348)		 RGD PMID:11375348 PMID:1380456 RGD:8553725 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Irs2 insulin receptor substrate 2 involved_in ISO (PMID:11375348) RGD PMID:11375348 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Irs3 insulin receptor substrate 3 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr12:19,053,148...19,055,286
Ensembl chr12:19,053,148...19,055,286 		JBrowse link
G Itgb1 integrin subunit beta 1 involved_in ISO (PMID:24044949) RGD PMID:24044949 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 involved_in ISO (PMID:20616313) RGD PMID:20616313 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037 		JBrowse link
G Itsn1 intersectin 1 acts_upstream_of_or_within ISO (PMID:17875942) RGD PMID:17875942 NCBI chr11:30,978,590...31,160,645
Ensembl chr11:30,978,590...31,160,645 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO (MGI:3828423|PMID:7782332) RGD PMID:7782332 MGI:3828423 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Kdr kinase insert domain receptor involved_in IMP
IEA
ISO		 GO_REF:0000107
(PMID:24863063), (PMID:9804796)		 Ensembl
RGD		 PMID:9804796 PMID:24863063 PMID:18221855 GO_REF:0000107, RGD:2292019 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Lep leptin involved_in ISS
IDA
ISO
IBA		 GO_REF:0000024
PMID:11677594
(MGI:4821191|PMID:20620997), (MGI:5700303|PMID:16825198)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:16825198 PMID:20620997 PMID:11677594 GO_REF:0000024 GO_REF:0000033 MGI:4821191 MGI:5700303, RGD:10448951 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lin28a lin-28 homolog A involved_in ISO (MGI:5294254|PMID:21962509) RGD PMID:21962509 MGI:5294254 NCBI chr 5:146,227,119...146,244,122
Ensembl chr 5:146,227,119...146,244,122 		JBrowse link
G Ltk leukocyte receptor tyrosine kinase involved_in ISO (PMID:9223670) RGD PMID:9223670 NCBI chr 3:106,734,675...106,741,552
Ensembl chr 3:106,734,676...106,743,369 		JBrowse link
G Maz MYC associated zinc finger protein involved_in ISO (PMID:25487955) RGD PMID:25487955 NCBI chr 1:181,629,742...181,635,193
Ensembl chr 1:181,629,729...181,650,408 		JBrowse link
G Meis3 Meis homeobox 3 acts_upstream_of_or_within ISO (PMID:21059917) RGD PMID:21059917 NCBI chr 1:76,861,267...76,872,691
Ensembl chr 1:76,861,924...76,872,691 		JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase acts_upstream_of_or_within ISO MGI:95660 (PMID:15650770) RGD PMID:15650770 NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:29168081) RGD PMID:29168081 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Mir126a microRNA 126a acts_upstream_of ISO (PMID:28578351) RGD PMID:28578351 NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180 		JBrowse link
G Mir205 microRNA 205 acts_upstream_of_or_within ISO (PMID:23974039) RGD PMID:23974039 NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985 		JBrowse link
G Mir21 microRNA 21 acts_upstream_of IMP
ISO		 (PMID:16762633), (PMID:22879939) RGD PMID:16762633 PMID:22879939 PMID:31759996 RGD:41410819 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir29a microRNA 29a acts_upstream_of ISO (PMID:21573166) RGD PMID:21573166 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir494 microRNA 494 acts_upstream_of_or_within ISO (PMID:20837890) RGD PMID:20837890 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Mir675 microRNA 675 acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 1:197,732,275...197,732,358
Ensembl chr 1:197,732,275...197,732,358 		JBrowse link
G Mst1r macrophage stimulating 1 receptor involved_in ISO (PMID:12676986) RGD PMID:12676986 NCBI chr 8:108,596,100...108,611,441
Ensembl chr 8:108,597,299...108,612,455 		JBrowse link
G Mtdh metadherin involved_in ISO
IEA		 (PMID:17704808)
GO_REF:0000107		 RGD
Ensembl		 PMID:17704808 GO_REF:0000107 NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413 		JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:17110594 RGD:2307383 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Mup4l1 major urinary protein 4 like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 5:75,221,340...75,224,797
Ensembl chr 5:75,142,157...75,564,845 		JBrowse link
G Musk muscle associated receptor tyrosine kinase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:73,058,427...73,169,696
Ensembl chr 5:73,058,121...73,171,932 		JBrowse link
G Mydgf myeloid-derived growth factor involved_in ISO (MGI:5609664|PMID:25581518) RGD PMID:25581518 MGI:5609664 NCBI chr 9:999,659...1,008,804
Ensembl chr 9:1,000,722...1,008,822 		JBrowse link
G Myoc myocilin involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:21656515)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:21656515 GO_REF:0000024 GO_REF:0000107 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127 		JBrowse link
G Myorg myogenesis regulating glycosidase acts_upstream_of_or_within ISO (PMID:19706595) RGD PMID:19706595 NCBI chr 5:56,654,257...56,664,467
Ensembl chr 5:56,648,643...56,664,440 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 involved_in ISO (PMID:26514923) RGD PMID:26514923 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Ndp norrin cystine knot growth factor NDP involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:29079753)		 Ensembl
RGD		 PMID:29079753 GO_REF:0000107 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase involved_in ISO
IEA		 (PMID:17218260)
GO_REF:0000107		 RGD
Ensembl		 PMID:17218260 GO_REF:0000107 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951 		JBrowse link
G Ngfr nerve growth factor receptor IDA RGD PMID:19457114 RGD:5508731 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO (PMID:20395202) RGD PMID:20395202 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nox4 NADPH oxidase 4 involved_in ISO
IEA		 (MGI:5009390|PMID:17942966)
GO_REF:0000107		 RGD
Ensembl		 PMID:17942966 GO_REF:0000107 MGI:5009390 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Nrg1 neuregulin 1 acts_upstream_of_or_within ISO (PMID:20448149) RGD PMID:20448149 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nrxn1 neurexin 1 involved_in ISO (PMID:26078884) RGD PMID:26078884 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 involved_in IMP
IBA		 PMID:10985347
GO_REF:0000033		 GO_Central PMID:10985347 GO_REF:0000033, RGD:8553408 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286 		JBrowse link
G Nts neurotensin acts_upstream_of
involved_in		 ISO
IEA		 (PMID:21806946)
GO_REF:0000107		 RGD
Ensembl		 PMID:21806946 GO_REF:0000107 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423 		JBrowse link
G Osbpl8 oxysterol binding protein-like 8 involved_in
acts_upstream_of_or_within		 ISO (MGI:5644010|PMID:23812417)
(PMID:21441927)		 RGD PMID:21441927 PMID:23812417 MGI:5644010 NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888 		JBrowse link
G Osm oncostatin M involved_in ISO RNAcentral:URS0000574A2C_9606 (PMID:28972028) RGD PMID:28972028 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313 		JBrowse link
G P2rx4 purinergic receptor P2X 4 involved_in IMP PMID:17299767 ARUK-UCL PMID:17299767 RGD:13673751 NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253 		JBrowse link
G P2ry12 purinergic receptor P2Y12 involved_in IMP PMID:18183622
PMID:17299767
PMID:20091784		 RGD
ARUK-UCL		 PMID:15056287 PMID:18183622 PMID:17299767 PMID:20091784 RGD:1580185, RGD:13673786, RGD:13673751, RGD:6480646 NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361 		JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(PMID:11788434), (PMID:19019919)
GO_REF:0000033		 UniProt
Ensembl
RGD
GO_Central		 PMID:11788434 PMID:19019919 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:10734101), (PMID:11788434), (PMID:16530387), (PMID:17942966), (PMID:19126672)
GO_REF:0000107
MGI:1349482|MGI:1890662 (PMID:16456542)
GO_REF:0000033		 UniProt
RGD
Ensembl
GO_Central		 PMID:10734101 PMID:11788434 PMID:16456542 PMID:16530387 PMID:17942966 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfc platelet derived growth factor C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:166,316,870...166,493,449
Ensembl chr 2:166,316,803...166,493,433 		JBrowse link
G Pdgfd platelet derived growth factor D involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:1646396)		 UniProt
Ensembl
RGD		 PMID:1646396 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5009390|PMID:17942966)
GO_REF:0000107
(PMID:1314164)		 UniProt
RGD
Ensembl		 PMID:1314164 PMID:17942966 GO_REF:0000024 GO_REF:0000107 MGI:5009390 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Phb1 prohibitin 1 involved_in IMP PMID:32173312 UniProt PMID:32173312 RGD:30309944 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 involved_in IMP PMID:20819118 UniProt PMID:20819118 RGD:8693633 NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (MGI:5305503|PMID:22187460), (MGI:5305504|PMID:22187458) RGD PMID:22187458 PMID:22187460 MGI:5305503 MGI:5305504 NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha involved_in ISO UniProtKB:P15692 (PMID:30496354) RGD PMID:30496354 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma involved_in ISO (PMID:12507995) RGD PMID:12507995 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043 		JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 involved_in ISO (PMID:12507995) RGD PMID:12507995 NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374 		JBrowse link
G Pld2 phospholipase D2 IMP RGD PMID:15705590 RGD:2299907 NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808 		JBrowse link
G Plxnb1 plexin B1 involved_in ISO (MGI:4413657|PMID:19788569) RGD PMID:19788569 MGI:4413657 NCBI chr 8:109,743,470...109,769,153
Ensembl chr 8:109,744,697...109,769,027 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta acts_upstream_of_or_within ISO (PMID:16581799) RGD PMID:16581799 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Prkd1 protein kinase D1 involved_in ISO (PMID:22095288) RGD PMID:22095288 NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042 		JBrowse link
G Prr5 proline rich 5 acts_upstream_of_or_within ISO MGI:1919696 (PMID:21413931) RGD PMID:21413931 NCBI chr 7:115,795,351...115,837,880
Ensembl chr 7:115,813,954...115,834,834 		JBrowse link
G Prr5l proline rich 5 like involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1924714 (PMID:21413931)		 Ensembl
RGD		 PMID:21413931 GO_REF:0000107 NCBI chr 3:88,001,951...88,173,532
Ensembl chr 3:88,003,617...88,082,763 		JBrowse link
G Ptk2 protein tyrosine kinase 2 involved_in ISS
ISO		 GO_REF:0000024
RNAcentral:URS000060A1F4_9606 (PMID:15166238), (PMID:26944318)		 UniProt
RGD		 PMID:15166238 PMID:26944318 GO_REF:0000024 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta acts_upstream_of_positive_effect ISS
ISO		 GO_REF:0000024
(MGI:3583523|PMID:12960403)		 UniProt
RGD		 PMID:12960403 GO_REF:0000024 MGI:3583523 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in ISO
IEA		 (PMID:19838216)
GO_REF:0000107		 RGD
Ensembl		 PMID:19838216 GO_REF:0000107 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO (PMID:18936167) RGD PMID:18936167 NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260 		JBrowse link
G Rac1 Rac family small GTPase 1 acts_upstream_of_or_within ISO (PMID:15728722) RGD PMID:15728722 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Ralgdsl2 ral guanine nucleotide dissociation stimulator like 2 acts_upstream_of_or_within ISO (PMID:24069211) RGD PMID:24069211 NCBI chr20:4,948,495...4,956,774
Ensembl chr20:4,948,497...4,969,911 		JBrowse link
G Ramp3 receptor activity modifying protein 3 involved_in ISO ComplexPortal:CPX-1134|UniProtKB:P30988 (PMID:22500019) RGD PMID:22500019 NCBI chr14:81,527,404...81,544,905
Ensembl chr14:81,527,385...81,544,902 		JBrowse link
G Rasd2 RASD family, member 2 involved_in IDA PMID:14724584 UniProt PMID:14724584 RGD:1304287 NCBI chr19:13,594,291...13,605,016
Ensembl chr19:13,594,291...13,605,016 		JBrowse link
G Rbm12 RNA binding motif protein 12 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:144,609,661...144,629,911
Ensembl chr 3:144,611,623...144,629,915
Ensembl chr 3:144,611,623...144,629,915 		JBrowse link
G Reln reelin involved_in ISO
IEA		 (MGI:5286805|PMID:21664258)
GO_REF:0000107		 RGD
Ensembl		 PMID:21664258 GO_REF:0000107 MGI:5286805 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Ret ret proto-oncogene involved_in ISS
ISO		 GO_REF:0000024
(PMID:28846097)		 UniProt
RGD		 PMID:28846097 GO_REF:0000024 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:17110594 GO_REF:0000033, RGD:2307383 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426 		JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155 		JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152 		JBrowse link
G Rtn4 reticulon 4 involved_in ISO
IEA		 (PMID:27353365)
GO_REF:0000107		 RGD
Ensembl		 PMID:27353365 GO_REF:0000107 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686 		JBrowse link
G Selp selectin P involved_in ISO
IEA		 (PMID:17632516)
GO_REF:0000107		 RGD
Ensembl		 PMID:17632516 GO_REF:0000107 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Sema3e semaphorin 3E involved_in ISO (PMID:25985275) RGD PMID:25985275 NCBI chr 4:20,297,534...20,555,287
Ensembl chr 4:20,299,718...20,555,229 		JBrowse link
G Sema4d semaphorin 4D involved_in ISO (PMID:16055703) RGD PMID:16055703 NCBI chr17:13,430,324...13,537,146
Ensembl chr17:13,430,379...13,537,138 		JBrowse link
G Sema5a semaphorin 5A involved_in ISS
ISO		 GO_REF:0000024
(MGI:5526935|PMID:19850054)		 UniProt
RGD		 PMID:19850054 GO_REF:0000024 MGI:5526935 NCBI chr 2:83,309,843...83,741,084
Ensembl chr 2:83,309,843...83,741,084 		JBrowse link
G Serpina12 serpin family A member 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5568548 (PMID:22837305)		 Ensembl
RGD		 PMID:22837305 GO_REF:0000107 NCBI chr 6:122,952,552...122,967,271
Ensembl chr 6:122,952,552...122,967,271 		JBrowse link
G Sesn2 sestrin 2 acts_upstream_of_or_within ISO MGI:3587950 (PMID:22958918) RGD PMID:22958918 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (MGI:4821191|PMID:20620997)
GO_REF:0000107		 RGD
Ensembl		 PMID:20620997 GO_REF:0000107 MGI:4821191 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO (MGI:4950303|PMID:21367821) RGD PMID:21367821 MGI:4950303 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like acts_upstream_of_or_within ISO MGI:4124253 (PMID:26787558) RGD PMID:26787558 NCBI chr20:13,337,983...13,443,665
Ensembl chr20:13,339,692...13,443,665 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in ISO (PMID:18070883) RGD PMID:18070883 NCBI chr15:82,692,291...82,697,408
Ensembl chr15:82,692,143...82,698,009 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO
IMP		 (PMID:19767770)
PMID:16530387		 RGD PMID:19767770 PMID:16530387 RGD:8553998 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Stk3 serine/threonine kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:104798|MGI:1929004 (PMID:20080598)		 Ensembl
RGD		 PMID:20080598 GO_REF:0000107 NCBI chr 7:66,053,209...66,323,292
Ensembl chr 7:66,052,345...66,323,233 		JBrowse link
G Stox1 storkhead box 1 involved_in ISO (MGI:5635320|PMID:25677106) RGD PMID:25677106 MGI:5635320 NCBI chr20:30,598,284...30,666,371
Ensembl chr20:30,598,168...30,666,939 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of ISO (PMID:19386626) RGD PMID:19386626 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
G Tek TEK receptor tyrosine kinase acts_upstream_of_or_within_positive_effect
involved_in		 ISO
IBA		 (PMID:18425120)
(PMID:19615361)
GO_REF:0000033		 RGD
GO_Central		 PMID:18425120 PMID:19615361 GO_REF:0000033 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:18625725) RGD PMID:18625725 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO
ISS		 (PMID:18223299)
GO_REF:0000024		 RGD
AgBase		 PMID:18223299 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO
IEA		 (PMID:18625725)
GO_REF:0000107		 RGD
Ensembl		 PMID:18625725 GO_REF:0000107 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18653767) RGD PMID:18653767 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Thpo thrombopoietin involved_in ISO
ISS
IEA		 (PMID:15337790)
GO_REF:0000024
(MGI:5314162|PMID:22128142)
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:15337790 PMID:22128142 GO_REF:0000024 GO_REF:0000107 MGI:5314162 Ensembl chr11:80,182,820...80,188,167 JBrowse link
G Thpol1 thrombopoietin like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Tmem100 transmembrane protein 100 acts_upstream_of_or_within ISO MGI:5432904|MGI:5432905 (PMID:22783020) RGD PMID:22783020 NCBI chr10:74,854,779...74,861,147
Ensembl chr10:74,854,468...74,862,941 		JBrowse link
G Tnf tumor necrosis factor involved_in
acts_upstream_of_or_within		 IMP
ISO		 PMID:12729461
(PMID:20080598)		 RGD PMID:20080598 PMID:12729461 RGD:13673777 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1859962 (PMID:11051546)		 Ensembl
RGD		 PMID:11051546 GO_REF:0000107 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tpbg trophoblast glycoprotein acts_upstream_of_or_within ISO MGI:103556 (PMID:22956548) RGD PMID:22956548 NCBI chr 8:86,793,953...86,797,324
Ensembl chr 8:86,793,749...86,797,741 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6458378|PMID:30684126) RGD PMID:30684126 MGI:6458378 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Tspyl5 TSPY-like 5 involved_in ISO (PMID:20079711) RGD PMID:20079711 NCBI chr 7:64,881,504...64,885,512
Ensembl chr 7:64,884,225...64,885,457 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 GO_REF:0000107
MGI:95660 (PMID:15650770)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:15650770 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142 		JBrowse link
G Ube3a ubiquitin protein ligase E3A acts_upstream_of_or_within ISO MGI:2181811 (PMID:16254014) RGD PMID:16254014 NCBI chr 1:110,070,260...110,161,675
Ensembl chr 1:110,070,480...110,157,250 		JBrowse link
G Unc5b unc-5 netrin receptor B involved_in ISO
IEA		 (PMID:18469807)
GO_REF:0000107		 RGD
Ensembl		 PMID:18469807 GO_REF:0000107 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537 		JBrowse link
G Vav2 vav guanine nucleotide exchange factor 2 acts_upstream_of_or_within ISO MGI:1888518 (PMID:15728722) RGD PMID:15728722 NCBI chr 3:10,584,688...10,754,128
Ensembl chr 3:10,584,688...10,754,052 		JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 acts_upstream_of_or_within ISO MGI:102718 (PMID:15728722) RGD PMID:15728722 NCBI chr 2:197,011,901...197,354,321
Ensembl chr 2:197,011,831...197,354,321 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (MGI:5287519|PMID:21828096)
UniProtKB:P42336 (PMID:30496354)
UniProtKB:O00329 (PMID:24863063), (PMID:31915155)		 RGD PMID:21828096 PMID:24863063 PMID:30496354 PMID:31915155 MGI:5287519 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vegfb vascular endothelial growth factor B involved_in ISO (PMID:18259607) RGD PMID:18259607 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944 		JBrowse link
G Wnt16 Wnt family member 16 involved_in ISO (PMID:19951988) RGD PMID:19951988 NCBI chr 4:50,820,968...50,831,380
Ensembl chr 4:50,820,968...50,831,380 		JBrowse link
G Xbp1 X-box binding protein 1 NOT|involved_in ISO (PMID:26315405) RGD PMID:26315405 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19694
    positive regulation of biological process 6650
      positive regulation of signaling 2046
        positive regulation of signal transduction 1713
          positive regulation of intracellular signal transduction 1115
            positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction 202
Path 2
Term Annotations click to browse term
  biological_process 19694
    biological regulation 13309
      regulation of biological process 12906
        signaling 7595
          signal transduction 7020
            intracellular signal transduction 2744
              intracellular signaling cassette 1941
                phosphatidylinositol 3-kinase/protein kinase B signal transduction 342
                  regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction 298
                    positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction 202
paths to the root