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Gene: Phlpp1 (PH domain and leucine rich repeat protein phosphatase 1) Rattus norvegicus
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Symbol: Phlpp1
Name: PH domain and leucine rich repeat protein phosphatase 1
Description: Exhibits protein serine/threonine phosphatase activity. Involved in several processes, including hippocampus development; protein dephosphorylation; and regulation of intracellular signal transduction. Localizes to the cytoplasm; nucleus; and plasma membrane. Orthologous to human PHLPP1 (PH domain and leucine rich repeat protein phosphatase 1); PARTICIPATES IN protein kinase C (PKC) signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Circadian Oscillatory Protein (SCOP); PH domain and leucine rich repeat protein phosphatase; PH domain leucine-rich repeat protein phosphatase 1; PH domain leucine-rich repeat-containing protein phosphatase 1; PH domain-containing family E member 1; Phlpp; pleckstrin homology domain containing, family E (with leucine rich repeats) member 1; pleckstrin homology domain-containing family E member 1; pleckstrin homology domain-containing family E protein 1; Plekhe1; SCN circadian oscillatory protein; Scop; suprachiasmatic nucleus circadian oscillatory protein
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01326,145,989 - 26,394,505 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01331,302,241 - 31,550,366 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41312,315,824 - 12,565,692 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11312,343,187 - 12,565,692 (+)NCBI
Celera1322,176,081 - 22,397,222 (+)NCBICelera
Cytogenetic Map13p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Phlpp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621308
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.