Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
actin filament-based process +   
axon target recognition  
C21-steroid hormone metabolic process +   
cell activation +   
cell adhesion +   
cell adhesion molecule production +   
cell aggregation +   
cell communication +   
cell communication by chemical coupling +   
cell communication by electrical coupling +   
cell communication involved in cardiac conduction +   
cell competition in a multicellular organism  
cell cycle +   
cell cycle process +   
cell death +   
cell division +   
cell growth +   
cell killing +   
cell motility +   
cell population proliferation +   
cell recognition +   
cell wall organization or biogenesis +   
cell-cell fusion +   
cell-cell signaling +   
cellular component organization or biogenesis +   
cellular detoxification +   
cellular developmental process +   
cellular localization +   
cellular metabolic process +   
cellular pigment accumulation +   
cellular pigmentation +   
cellular process involved in reproduction in multicellular organism +   
cellular response to biotic stimulus +   
cellular response to cell wall damage 
cellular response to chemical stimulus +   
cellular response to differentiation-inducing factor 2 
cellular response to environmental stimulus +   
cellular response to extracellular stimulus +   
cellular response to lipoprotein particle stimulus +   
cellular response to stimulus +   
cellular response to stress +   
ciliary basal body segregation 
cytolysis +   
DNA clamp unloading  
ensheathment of neurons +   
establishment or maintenance of cell polarity +   
establishment or maintenance of cell type involved in phenotypic switching  
execution phase of apoptosis +   
execution phase of necroptosis  
exocytic process +   
export from cell +   
extracellular matrix-cell signaling +   
horizontal gene transfer +  
intercellular transport +   
intermediate filament-based process +   
light absorption +   
localization of cell +   
maintenance of location in cell +   
membrane docking +   
microtubule organizing center localization +   
microtubule-based process +   
mineralocorticoid metabolic process +   
motogenic signaling initiating cell movement in cerebral cortex +  
motogenic signaling involved in interneuron migration from the subpallium to the cortex 
motogenic signaling involved in postnatal olfactory bulb interneuron migration  
negative regulation of cell communication +   
negative regulation of cellular process +   
negative regulation of signaling +   
phenotypic switching +   
plasmid maintenance +  
pollen-pistil interaction +  
positive regulation of cell communication +   
positive regulation of cellular process +   
positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization  
positive regulation of signaling +   
process utilizing autophagic mechanism +   
protein folding +   
protein unfolding  
regulation of actin filament-based process +   
regulation of binding of sperm to zona pellucida +   
regulation of cartilage condensation +  
regulation of cell activation +   
regulation of cell adhesion +   
regulation of cell adhesion molecule production +   
regulation of cell communication +   
regulation of cell cycle +   
regulation of cell differentiation +   
regulation of cell division +   
regulation of cell fate commitment +   
regulation of cell fate determination +   
regulation of cell killing +   
regulation of cell motility +   
regulation of cell population proliferation +   
regulation of cell wall organization or biogenesis +  
regulation of cellular component biogenesis +   
regulation of cellular component organization +   
regulation of cellular localization +   
regulation of cellular metabolic process +   
regulation of cellular process +   
regulation of cellular response to alcohol +   
regulation of cellular response to alkaline pH +  
regulation of cellular response to drug +   
regulation of cellular response to gamma radiation +  
regulation of cellular response to insulin stimulus +   
regulation of cellular response to macrophage colony-stimulating factor stimulus +   
regulation of cellular response to manganese ion +  
regulation of cellular response to oxidopamine +  
regulation of cellular response to stress +   
regulation of cellular response to testosterone stimulus +   
regulation of cellular response to very-low-density lipoprotein particle stimulus +   
regulation of cellular response to X-ray +   
regulation of cytolysis +   
regulation of establishment or maintenance of cell polarity +   
regulation of execution phase of apoptosis +   
regulation of horizontal cell localization +  
regulation of melanosome transport +   
regulation of membrane depolarization +   
regulation of microtubule-based process +   
regulation of myelination +   
regulation of opsonization +   
regulation of phenotypic switching +   
regulation of programmed cell death +   
regulation of protein folding +   
regulation of response to cell cycle checkpoint signaling +   
regulation of secretion by cell +   
regulation of septum digestion after cytokinesis +  
regulation of sequestering of calcium ion +   
regulation of signaling +   
regulation of single-species biofilm formation +   
regulation of spore germination +  
regulation of stomatal movement +  
regulation of synaptic vesicle transport +   
regulation of transmembrane transport +   
regulation of vascular associated smooth muscle cell dedifferentiation +   
regulation of vesicle docking +   
regulation of vesicle-mediated transport +   
response to pheromone regulating conjugation with mutual genetic exchange +  
RNA folding +   
septum digestion after cytokinesis +  
sex determination, somatic-gonadal interaction 
signal transduction +   
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
skeletal muscle fiber adaptation  
stomatal movement +  
symbiont-mediated perturbation of host cellular process +  
synaptic vesicle transport +   
syncytium formation +   
transmembrane transport +   
transmission of nerve impulse +   
transposition +   
vesicle targeting +   
vesicle-mediated transport +   
 apoptotic signaling pathway +   
 bile acid signaling pathway +   
 calmodulin dependent kinase signaling pathway +   
 carbohydrate mediated signaling +   
 cell surface receptor signaling pathway +   
 chloroplast-nucleus signaling pathway 
 dopamine receptor signaling pathway +   
 endoplasmic reticulum unfolded protein response +   
 ER-nucleus signaling pathway +   
 extracellular ATP signaling 
 G protein-coupled receptor signaling pathway +   
 granzyme-mediated programmed cell death signaling pathway +   
 hormone-mediated signaling pathway +   
 hydrogen peroxide mediated signaling pathway +  
 hypoxia-inducible factor-1alpha signaling pathway +   
 immune response-regulating signaling pathway +   
 intracellular receptor signaling pathway +   
 intracellular signal transduction +   
 ligand-gated ion channel signaling pathway +   
 lipoprotein particle mediated signaling +   
 mitochondria-nucleus signaling pathway  
 necroptotic signaling pathway  
 negative regulation of signal transduction +   
 neuronal signal transduction +   
 opioid growth factor receptor signaling pathway 
 phototransduction +   
 positive regulation of signal transduction +   
 postsynaptic signal transduction +   
 presynaptic signal transduction +   
 red or far-red light signaling pathway +   
 regulation of blood pressure by chemoreceptor signaling pathway 
 regulation of floral organ abscission by signal transduction 
 regulation of signal transduction +   
 salicylic acid mediated signaling pathway +  
 serotonin receptor signaling pathway +   
 signal transduction in absence of ligand +   
 signal transduction involved in cellular response to ammonium ion 
 signal transduction involved in filamentous growth 
 signal transduction involved in positive regulation of conjugation with cellular fusion +  
 signal transduction involved in regulation of gene expression  
 sphingolipid mediated signaling pathway +   

Synonyms
Narrow Synonyms: signaling cascade ;   signalling cascade
Related Synonyms: signaling pathway ;   signalling pathway
Alternate IDs: GO:0023014 ;   GO:0023015 ;   GO:0023016 ;   GO:0023033 ;   GO:0023045
Xrefs: Wikipedia:Signal_transduction
Definition Sources: GOC:go_curators, GOC:mtg_signaling_feb11

paths to the root