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ONTOLOGY REPORT - ANNOTATIONS


Term:intracellular signal transduction
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Accession:GO:0035556 term browser browse the term
Definition:The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
Synonyms:exact_synonym: intracellular signaling chain
 narrow_synonym: intracellular protein kinase cascade;   intracellular signal transduction pathway;   protein kinase cascade;   signal transmission via intracellular cascade
 related_synonym: intracellular signaling cascade;   intracellular signaling pathway;   signal transduction via intracellular signaling cascade
 alt_id: GO:0007242;   GO:0007243;   GO:0023013;   GO:0023034



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  • Term paths to the root
    Path 1
    Term Annotations click to browse term
      biological_process 18734
        signaling 7370
          signal transduction 6808
            intracellular signal transduction 2667
              I-kappaB kinase/NF-kappaB signaling + 292
              MAPK cascade + 850
              NIK/NF-kappaB signaling + 138
              PKR-mediated signaling 0
              RAM/MOR signaling pathway 0
              TOR signaling + 136
              TRAF-mediated signal transduction 1
              cell cycle checkpoint signaling + 175
              cytoplasmic pattern recognition receptor signaling pathway + 54
              endosomal signal transduction 0
              hippo signaling + 40
              inositol lipid-mediated signaling + 187
              intracellular signal transduction involved in positive regulation of cell growth 0
              intrinsic apoptotic signaling pathway + 315
              negative regulation of intracellular signal transduction + 588
              osmosensory signaling pathway + 3
              phosphorelay signal transduction system + 0
              positive regulation of intracellular signal transduction + 1087
              protein kinase A signaling + 39
              protein kinase B signaling + 236
              protein kinase C signaling + 41
              protein kinase D signaling + 4
              regulation of intracellular signal transduction + 1778
              second-messenger-mediated signaling + 345
              signal transduction by p53 class mediator + 156
              signal transduction downstream of smoothened + 4
              signal transduction in response to DNA damage + 178
              signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle 0
              small GTPase mediated signal transduction + 451
              stress-activated protein kinase signaling cascade + 264
    Path 2
    Term Annotations click to browse term
      biological_process 18734
        biological regulation 13314
          regulation of biological process 12594
            regulation of cellular process 11909
              signal transduction 6808
                intracellular signal transduction 2667
                  I-kappaB kinase/NF-kappaB signaling + 292
                  MAPK cascade + 850
                  NIK/NF-kappaB signaling + 138
                  PKR-mediated signaling 0
                  RAM/MOR signaling pathway 0
                  TOR signaling + 136
                  TRAF-mediated signal transduction 1
                  cell cycle checkpoint signaling + 175
                  cytoplasmic pattern recognition receptor signaling pathway + 54
                  endosomal signal transduction 0
                  hippo signaling + 40
                  inositol lipid-mediated signaling + 187
                  intracellular signal transduction involved in positive regulation of cell growth 0
                  intrinsic apoptotic signaling pathway + 315
                  negative regulation of intracellular signal transduction + 588
                  osmosensory signaling pathway + 3
                  phosphorelay signal transduction system + 0
                  positive regulation of intracellular signal transduction + 1087
                  protein kinase A signaling + 39
                  protein kinase B signaling + 236
                  protein kinase C signaling + 41
                  protein kinase D signaling + 4
                  regulation of intracellular signal transduction + 1778
                  second-messenger-mediated signaling + 345
                  signal transduction by p53 class mediator + 156
                  signal transduction downstream of smoothened + 4
                  signal transduction in response to DNA damage + 178
                  signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle 0
                  small GTPase mediated signal transduction + 451
                  stress-activated protein kinase signaling cascade + 264
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