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ONTOLOGY REPORT - ANNOTATIONS


Term:intracellular signal transduction
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Accession:GO:0035556 term browser browse the term
Definition:The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
Synonyms:exact_synonym: intracellular signaling chain
 narrow_synonym: intracellular protein kinase cascade;   intracellular signal transduction pathway;   protein kinase cascade;   signal transmission via intracellular cascade
 related_synonym: intracellular signaling cascade;   intracellular signaling pathway;   signal transduction via intracellular signaling cascade
 alt_id: GO:0007242;   GO:0007243;   GO:0023013;   GO:0023034


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  • Term paths to the root
    Path 1
    Term Annotations click to browse term
      biological_process 19491
        signaling 7458
          signal transduction 6881
            intracellular signal transduction 2607
              I-kappaB kinase/NF-kappaB signaling + 279
              MAPK cascade + 811
              NIK/NF-kappaB signaling + 126
              PKR-mediated signaling 0
              RAM/MOR signaling pathway 0
              TOR signaling + 133
              TRAF-mediated signal transduction 1
              cell cycle checkpoint signaling + 173
              cytoplasmic pattern recognition receptor signaling pathway + 53
              endosomal signal transduction 0
              hippo signaling + 39
              inositol lipid-mediated signaling + 183
              intracellular signal transduction involved in positive regulation of cell growth 0
              intrinsic apoptotic signaling pathway + 308
              negative regulation of intracellular signal transduction + 545
              osmosensory signaling pathway + 3
              phosphorelay signal transduction system + 0
              positive regulation of intracellular signal transduction + 1046
              protein kinase A signaling + 36
              protein kinase B signaling + 214
              protein kinase C signaling + 39
              protein kinase D signaling + 4
              regulation of intracellular signal transduction + 1686
              second-messenger-mediated signaling + 343
              signal transduction by p53 class mediator + 145
              signal transduction downstream of smoothened + 4
              signal transduction in response to DNA damage + 175
              signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle 0
              small GTPase mediated signal transduction + 447
              stress-activated protein kinase signaling cascade + 256
    Path 2
    Term Annotations click to browse term
      biological_process 19491
        biological regulation 13515
          regulation of biological process 12773
            regulation of cellular process 12275
              signal transduction 6881
                intracellular signal transduction 2607
                  I-kappaB kinase/NF-kappaB signaling + 279
                  MAPK cascade + 811
                  NIK/NF-kappaB signaling + 126
                  PKR-mediated signaling 0
                  RAM/MOR signaling pathway 0
                  TOR signaling + 133
                  TRAF-mediated signal transduction 1
                  cell cycle checkpoint signaling + 173
                  cytoplasmic pattern recognition receptor signaling pathway + 53
                  endosomal signal transduction 0
                  hippo signaling + 39
                  inositol lipid-mediated signaling + 183
                  intracellular signal transduction involved in positive regulation of cell growth 0
                  intrinsic apoptotic signaling pathway + 308
                  negative regulation of intracellular signal transduction + 545
                  osmosensory signaling pathway + 3
                  phosphorelay signal transduction system + 0
                  positive regulation of intracellular signal transduction + 1046
                  protein kinase A signaling + 36
                  protein kinase B signaling + 214
                  protein kinase C signaling + 39
                  protein kinase D signaling + 4
                  regulation of intracellular signal transduction + 1686
                  second-messenger-mediated signaling + 343
                  signal transduction by p53 class mediator + 145
                  signal transduction downstream of smoothened + 4
                  signal transduction in response to DNA damage + 175
                  signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle 0
                  small GTPase mediated signal transduction + 447
                  stress-activated protein kinase signaling cascade + 256
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