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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:aconitine
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Accession:CHEBI:2430 term browser browse the term
Definition:A diterpenoid that is 20-ethyl-3alpha,13,15alpha-trihydroxy-1alpha,6alpha,16beta-trimethoxy-4-(methoxymethyl)aconitane-8,14alpha-diol having acetate and benzoate groups at the 8- and 14-positions respectively.
Synonyms:exact_synonym: 20-ethyl-3alpha,13,15alpha-trihydroxy-1alpha,6alpha,16beta-trimethoxy-4-(methoxymethyl)aconitane-8,14alpha-diyl 8-acetate 14-benzoate
 related_synonym: 16-Ethyl-1alpha,6alpha,19beta-trimethoxy-4-(methoxymethyl)-aconitane-3alpha,8,10alpha,11,18alpha-pentol, 8-acetate 10-benzoate;   Formula=C34H47NO11;   InChI=1S/C34H47NO11/c1-7-35-15-31(16-41-3)20(37)13-21(42-4)33-19-14-32(40)28(45-30(39)18-11-9-8-10-12-18)22(19)34(46-17(2)36,27(38)29(32)44-6)23(26(33)35)24(43-5)25(31)33/h8-12,19-29,37-38,40H,7,13-16H2,1-6H3/t19-,20-,21+,22-,23+,24+,25-,26?,27+,28-,29+,31+,32-,33+,34-/m1/s1;   InChIKey=XFSBVAOIAHNAPC-XTHSEXKGSA-N;   SMILES=[H][C@]12C[C@]3(O)[C@@H](OC)[C@H](O)[C@](OC(C)=O)([C@@]4([H])[C@H](OC)[C@]5([H])[C@]6(COC)CN(CC)C4[C@]15[C@H](C[C@H]6O)OC)[C@@]2([H])[C@H]3OC(=O)c1ccccc1
 xref: CAS:302-27-2;   KEGG:C06091;   KNApSAcK:C00001611
 xref_mesh: MESH:D000157
 xref: PMID:12951473;   PMID:14979521;   PMID:16293382;   PMID:16315485;   PMID:16949890;   PMID:17276394;   PMID:17327465;   PMID:18329015;   PMID:18448863;   PMID:19967988;   PMID:20717872;   PMID:20886302;   PMID:20937638;   PMID:20953393;   PMID:21277363;   PMID:21377951;   PMID:21505405;   PMID:21512442;   PMID:21782880;   PMID:9459571;   Reaxys:74608


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aconitine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1110004F10Rik RIKEN cDNA 1110004F10 gene increases expression ISO Aconitine results in increased expression of C1H11ORF58 protein CTD PMID:33236894 NCBI chr 7:115,680,596...115,704,445
Ensembl chr 7:115,638,632...115,704,445 		JBrowse link
G Aak1 AP2 associated kinase 1 increases expression ISO Aconitine results in increased expression of AAK1 protein CTD PMID:33236894 NCBI chr 6:86,826,252...86,980,209
Ensembl chr 6:86,826,499...86,980,205 		JBrowse link
G Aars2 alanyl-tRNA synthetase 2, mitochondrial increases expression ISO Aconitine results in increased expression of AARS2 protein CTD PMID:33236894 NCBI chr17:45,817,473...45,831,769
Ensembl chr17:45,817,767...45,831,769 		JBrowse link
G Abcb11 ATP-binding cassette, sub-family B member 11 multiple interactions ISO Aconitine inhibits the reaction [ABCB11 protein results in increased transport of Taurodeoxycholic Acid] CTD PMID:35101544 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958 		JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A decreases response to substance
affects transport
multiple interactions
affects response to substance		 ISO
EXP		 ABCB1 results in decreased susceptibility to Aconitine
ABCB1 affects the transport of Aconitine
ABCB1A gene mutant form promotes the reaction [Aconitine results in increased expression of S100B protein]; ABCB1A gene mutant form results in decreased metabolism of and results in increased abundance of Aconitine
ABCB1A gene mutant form affects the susceptibility to Aconitine		 CTD PMID:23562926 PMID:28193520 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Acbd3 acyl-Coenzyme A binding domain containing 3 increases expression ISO Aconitine results in increased expression of ACBD3 protein CTD PMID:33236894 NCBI chr 1:180,553,608...180,581,769
Ensembl chr 1:180,553,608...180,581,769 		JBrowse link
G Acot7 acyl-CoA thioesterase 7 decreases expression ISO Aconitine results in decreased expression of ACOT7 protein CTD PMID:33236894 NCBI chr 4:152,258,872...152,356,312
Ensembl chr 4:152,262,591...152,356,312 		JBrowse link
G Acot9 acyl-CoA thioesterase 9 decreases expression ISO Aconitine results in decreased expression of ACOT9 protein CTD PMID:33236894 NCBI chr  X:154,045,439...154,080,650
Ensembl chr  X:154,045,439...154,080,650 		JBrowse link
G Acta1 actin alpha 1, skeletal muscle decreases expression ISO Aconitine results in decreased expression of ACTA1 protein CTD PMID:33236894 NCBI chr 8:124,618,497...124,621,514
Ensembl chr 8:124,618,508...124,621,490 		JBrowse link
G Actbl2 actin, beta-like 2 increases expression ISO Aconitine results in increased expression of ACTBL2 protein CTD PMID:33236894 NCBI chr13:111,391,547...111,394,283
Ensembl chr13:111,391,547...111,394,283 		JBrowse link
G Adprh ADP-ribosylarginine hydrolase decreases expression ISO Aconitine results in decreased expression of ADPRH protein CTD PMID:33236894 NCBI chr16:38,265,761...38,273,051
Ensembl chr16:38,264,392...38,273,065 		JBrowse link
G Ago1 argonaute RISC catalytic subunit 1 increases expression ISO Aconitine results in increased expression of AGO1 protein CTD PMID:33236894 NCBI chr 4:126,328,805...126,362,500
Ensembl chr 4:126,328,805...126,362,376 		JBrowse link
G Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 decreases expression ISO Aconitine results in decreased expression of AGPAT3 protein CTD PMID:33236894 NCBI chr10:78,105,008...78,188,335
Ensembl chr10:78,105,012...78,188,323 		JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression ISO Aconitine results in decreased expression of AIF1 protein CTD PMID:33236894 NCBI chr17:35,389,967...35,394,977
Ensembl chr17:35,389,967...35,395,044 		JBrowse link
G Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 decreases expression ISO Aconitine results in decreased expression of AIMP2 protein CTD PMID:33236894 NCBI chr 5:143,839,522...143,846,657
Ensembl chr 5:143,839,522...143,846,665 		JBrowse link
G Alad aminolevulinate, delta-, dehydratase increases expression ISO Aconitine results in increased expression of ALAD protein CTD PMID:33236894 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155 		JBrowse link
G Aldh3a2 aldehyde dehydrogenase family 3, subfamily A2 increases expression ISO Aconitine results in increased expression of ALDH3A2 protein CTD PMID:33236894 NCBI chr11:61,114,240...61,158,267
Ensembl chr11:61,114,243...61,158,290 		JBrowse link
G Aldoc aldolase C, fructose-bisphosphate increases expression ISO Aconitine results in increased expression of ALDOC protein CTD PMID:33236894 NCBI chr11:78,213,899...78,218,607
Ensembl chr11:78,213,794...78,218,607 		JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase increases expression ISO Aconitine results in increased expression of ALKBH3 protein CTD PMID:33236894 NCBI chr 2:93,810,979...93,841,099
Ensembl chr 2:93,810,895...93,841,152 		JBrowse link
G Amacr alpha-methylacyl-CoA racemase increases expression ISO Aconitine results in increased expression of AMACR protein CTD PMID:33236894 NCBI chr15:10,981,875...10,995,693
Ensembl chr15:10,981,842...10,996,712 		JBrowse link
G Ank1 ankyrin 1, erythroid increases expression ISO Aconitine results in increased expression of ANK1 protein CTD PMID:33236894 NCBI chr 8:23,464,852...23,640,517
Ensembl chr 8:23,464,860...23,640,513 		JBrowse link
G Ankrd13a ankyrin repeat domain 13a increases expression ISO Aconitine results in increased expression of ANKRD13A protein CTD PMID:33236894 NCBI chr 5:114,913,009...114,943,882
Ensembl chr 5:114,912,738...114,944,261 		JBrowse link
G Anks1 ankyrin repeat and SAM domain containing 1 decreases expression ISO Aconitine results in decreased expression of ANKS1A protein CTD PMID:33236894 NCBI chr17:28,128,273...28,281,753
Ensembl chr17:28,128,280...28,281,749 		JBrowse link
G Ano10 anoctamin 10 decreases expression ISO Aconitine results in decreased expression of ANO10 protein CTD PMID:33236894 NCBI chr 9:122,004,958...122,123,440
Ensembl chr 9:122,004,940...122,123,489 		JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A decreases expression ISO Aconitine results in decreased expression of ANP32A protein CTD PMID:33236894 NCBI chr 9:62,248,637...62,286,084
Ensembl chr 9:62,248,575...62,286,094 		JBrowse link
G Ap2m1 adaptor-related protein complex 2, mu 1 subunit increases expression ISO Aconitine results in increased expression of AP2M1 protein CTD PMID:33236894 NCBI chr16:20,354,230...20,363,659
Ensembl chr16:20,354,228...20,363,659 		JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 increases expression ISO Aconitine results in increased expression of APOBEC1 protein CTD PMID:33236894 NCBI chr 6:122,554,755...122,580,068
Ensembl chr 6:122,554,751...122,579,403 		JBrowse link
G Apoc2 apolipoprotein C2 decreases expression ISO Aconitine results in decreased expression of APOC2 protein CTD PMID:33236894 NCBI chr 7:19,405,504...19,411,866
Ensembl chr 7:19,405,504...19,411,866 		JBrowse link
G Apoc3 apolipoprotein C-III decreases expression ISO Aconitine results in decreased expression of APOC3 protein CTD PMID:33236894 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934 		JBrowse link
G Apom apolipoprotein M decreases expression ISO Aconitine results in decreased expression of APOM protein CTD PMID:33236894 NCBI chr17:35,347,973...35,350,777
Ensembl chr17:35,347,973...35,351,026 		JBrowse link
G Apool apolipoprotein O-like decreases expression ISO Aconitine results in decreased expression of APOOL protein CTD PMID:33236894 NCBI chr  X:111,221,049...111,282,452
Ensembl chr  X:111,221,031...111,282,452 		JBrowse link
G Arfgap3 ADP-ribosylation factor GTPase activating protein 3 increases expression ISO Aconitine results in increased expression of ARFGAP3 protein CTD PMID:33236894 NCBI chr15:83,183,940...83,234,576
Ensembl chr15:83,183,940...83,234,448 		JBrowse link
G Arhgap1 Rho GTPase activating protein 1 decreases expression ISO Aconitine results in decreased expression of ARHGAP1 protein CTD PMID:33236894 NCBI chr 2:91,480,463...91,502,670
Ensembl chr 2:91,480,205...91,502,671 		JBrowse link
G Armc8 armadillo repeat containing 8 increases expression ISO Aconitine results in increased expression of ARMC8 protein CTD PMID:33236894 NCBI chr 9:99,360,438...99,451,471
Ensembl chr 9:99,360,425...99,450,952 		JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B decreases expression ISO Aconitine results in decreased expression of ARPC1B protein CTD PMID:33236894 NCBI chr 5:145,051,066...145,064,996
Ensembl chr 5:145,051,025...145,067,515 		JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 decreases expression ISO Aconitine results in decreased expression of ARPC2 protein CTD PMID:33236894 NCBI chr 1:74,275,656...74,307,368
Ensembl chr 1:74,275,243...74,307,368 		JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 increases expression ISO Aconitine results in increased expression of ARPP19 protein CTD PMID:33236894 NCBI chr 9:74,944,896...74,967,595
Ensembl chr 9:74,944,896...74,967,595 		JBrowse link
G Atp1b3 ATPase, Na+/K+ transporting, beta 3 polypeptide decreases expression ISO Aconitine results in decreased expression of ATP1B3 protein CTD PMID:33236894 NCBI chr 9:96,214,708...96,246,368
Ensembl chr 9:96,214,708...96,246,495 		JBrowse link
G Atp5mk ATP synthase membrane subunit k decreases expression ISO Aconitine results in decreased expression of ATP5MK protein CTD PMID:33236894 NCBI chr19:47,071,910...47,079,086
Ensembl chr19:47,071,903...47,079,086 		JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b decreases expression ISO Aconitine results in decreased expression of ATP5PB protein CTD PMID:33236894 NCBI chr 3:105,850,014...105,866,579
Ensembl chr 3:105,850,014...105,867,415 		JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 decreases expression ISO Aconitine results in decreased expression of ATP5PF protein CTD PMID:33236894 NCBI chr16:84,624,754...84,632,495
Ensembl chr16:84,624,754...84,632,513 		JBrowse link
G Atp6v0d1 ATPase, H+ transporting, lysosomal V0 subunit D1 increases expression ISO Aconitine results in increased expression of ATP6V0D1 protein CTD PMID:33236894 NCBI chr 8:106,251,093...106,292,696
Ensembl chr 8:106,251,097...106,292,679 		JBrowse link
G Atp6v1f ATPase, H+ transporting, lysosomal V1 subunit F increases expression ISO Aconitine results in increased expression of ATP6V1F protein CTD PMID:33236894 NCBI chr 6:29,467,782...29,470,508
Ensembl chr 6:29,467,717...29,470,511 		JBrowse link
G Atpaf2 ATP synthase mitochondrial F1 complex assembly factor 2 decreases expression ISO Aconitine results in decreased expression of ATPAF2 protein CTD PMID:33236894 NCBI chr11:60,291,450...60,309,427
Ensembl chr11:60,291,452...60,309,283 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc increases expression ISO Aconitine results in increased expression of AZGP1 protein CTD PMID:33236894 NCBI chr 5:137,979,783...137,988,495
Ensembl chr 5:137,979,782...137,988,495 		JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 increases expression ISO Aconitine results in increased expression of BABAM1 protein CTD PMID:33236894 NCBI chr 8:71,848,809...71,857,416
Ensembl chr 8:71,849,505...71,857,263 		JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions		 ISO
EXP		 Aconitine results in increased expression of BAX protein
[Aconitine co-treated with Ruthenium Red] results in increased expression of BAX protein; [Aconitine co-treated with Spermine] results in increased expression of BAX protein		 CTD PMID:24840785 PMID:31975431 PMID:37506855 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G BC031181 cDNA sequence BC031181 increases expression ISO Aconitine results in increased expression of C18H18ORF32 protein CTD PMID:33236894 NCBI chr18:75,138,910...75,143,006
Ensembl chr18:75,138,939...75,143,223 		JBrowse link
G Bcap29 B cell receptor associated protein 29 increases expression ISO Aconitine results in increased expression of BCAP29 protein CTD PMID:33236894 NCBI chr12:31,645,353...31,684,657
Ensembl chr12:31,640,966...31,684,657 		JBrowse link
G Bcap31 B cell receptor associated protein 31 increases expression ISO Aconitine results in increased expression of BCAP31 protein CTD PMID:33236894 NCBI chr  X:72,729,784...72,761,464
Ensembl chr  X:72,729,784...72,759,781 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO Aconitine results in decreased expression of BCL2 protein CTD PMID:24840785 PMID:31975431 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bin1 bridging integrator 1 increases expression ISO Aconitine results in increased expression of BIN1 protein CTD PMID:33236894 NCBI chr18:32,509,671...32,568,793
Ensembl chr18:32,510,283...32,568,790 		JBrowse link
G Brox BRO1 domain and CAAX motif containing increases expression ISO Aconitine results in increased expression of BROX protein CTD PMID:33236894 NCBI chr 1:183,057,916...183,078,839
Ensembl chr 1:183,057,916...183,078,813 		JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression ISO Aconitine results in decreased expression of BST2 protein CTD PMID:33236894 NCBI chr 8:71,986,899...71,990,116
Ensembl chr 8:71,986,899...71,990,100 		JBrowse link
G Btbd1 BTB domain containing 1 increases expression ISO Aconitine results in increased expression of BTBD1 protein CTD PMID:33236894 NCBI chr 7:81,441,822...81,479,262
Ensembl chr 7:81,441,822...81,479,179 		JBrowse link
G Btf3 basic transcription factor 3 decreases expression ISO Aconitine results in decreased expression of BTF3 protein CTD PMID:33236894 NCBI chr13:98,446,405...98,453,514
Ensembl chr13:98,446,404...98,453,514 		JBrowse link
G C6 complement component 6 decreases expression ISO Aconitine results in decreased expression of C6 protein CTD PMID:33236894 NCBI chr15:4,756,550...4,833,527
Ensembl chr15:4,756,657...4,844,449 		JBrowse link
G Cab39 calcium binding protein 39 decreases expression ISO Aconitine results in decreased expression of CAB39 protein CTD PMID:33236894 NCBI chr 1:85,707,796...85,779,298
Ensembl chr 1:85,721,162...85,779,297 		JBrowse link
G Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit decreases expression ISO Aconitine results in decreased expression of CACNA1C protein CTD PMID:33236894 NCBI chr 6:118,564,201...119,174,345
Ensembl chr 6:118,564,201...119,173,851 		JBrowse link
G Cacnb2 calcium channel, voltage-dependent, beta 2 subunit increases expression ISO Aconitine results in increased expression of CACNB2 protein CTD PMID:33236894 NCBI chr 2:14,608,672...14,993,622
Ensembl chr 2:14,607,899...14,992,719 		JBrowse link
G Camk1 calcium/calmodulin-dependent protein kinase I increases expression ISO Aconitine results in increased expression of CAMK1 protein CTD PMID:33236894 NCBI chr 6:113,311,085...113,320,883
Ensembl chr 6:113,311,085...113,320,945 		JBrowse link
G Car2 carbonic anhydrase 2 increases expression ISO Aconitine results in increased expression of CA2 protein CTD PMID:33236894 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830 		JBrowse link
G Car4 carbonic anhydrase 4 increases expression ISO Aconitine results in increased expression of CA4 protein CTD PMID:33236894 NCBI chr11:84,848,580...84,856,880
Ensembl chr11:84,848,612...84,856,870 		JBrowse link
G Card19 caspase recruitment domain family, member 19 increases expression ISO Aconitine results in increased expression of CARD19 protein CTD PMID:33236894 NCBI chr13:49,356,426...49,369,471
Ensembl chr13:49,356,426...49,369,513 		JBrowse link
G Casp1 caspase 1 increases expression
multiple interactions		 EXP
ISO		 Aconitine results in increased expression of CASP1 protein
NLRP3 protein affects the reaction [Aconitine results in increased expression of CASP1 protein]; NOD1 protein affects the reaction [Aconitine results in increased expression of CASP1 protein]; NOD2 protein affects the reaction [Aconitine results in increased expression of CASP1 protein]		 CTD PMID:33236894 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290 		JBrowse link
G Casp3 caspase 3 increases expression
increases cleavage
multiple interactions		 ISO
EXP		 Aconitine results in increased expression of CASP3 protein
Aconitine results in increased cleavage of CASP3 protein
[Aconitine co-treated with Ruthenium Red] results in increased cleavage of CASP3 protein; [Aconitine co-treated with Spermine] results in increased cleavage of CASP3 protein		 CTD PMID:24840785 PMID:31975431 PMID:37506855 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp9 caspase 9 increases expression ISO Aconitine results in increased expression of CASP9 protein CTD PMID:24840785 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Ccdc163 coiled-coil domain containing 163 decreases expression ISO Aconitine results in decreased expression of CCDC163 protein CTD PMID:33236894 NCBI chr 4:116,565,537...116,572,881
Ensembl chr 4:116,565,706...116,608,403 		JBrowse link
G Ccdc43 coiled-coil domain containing 43 increases expression ISO Aconitine results in increased expression of CCDC43 protein CTD PMID:33236894 NCBI chr11:102,575,510...102,595,829
Ensembl chr11:102,575,512...102,588,608 		JBrowse link
G Ccdc9b coiled-coil domain containing 9B increases expression ISO Aconitine results in increased expression of CCDC9B protein CTD PMID:33236894 NCBI chr 2:118,584,626...118,593,421
Ensembl chr 2:118,584,639...118,593,142 		JBrowse link
G Cd200 CD200 molecule decreases expression ISO Aconitine results in decreased expression of CD200 protein CTD PMID:33236894 NCBI chr16:45,202,474...45,229,419
Ensembl chr16:45,202,498...45,229,416 		JBrowse link
G Cd93 CD93 antigen decreases expression ISO Aconitine results in decreased expression of CD93 protein CTD PMID:33236894 NCBI chr 2:148,278,571...148,285,455
Ensembl chr 2:148,278,560...148,285,483 		JBrowse link
G Cdk1 cyclin dependent kinase 1 decreases expression ISO
EXP		 Aconitine results in decreased expression of CDK1 mRNA CTD PMID:32598336 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768 		JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 decreases expression ISO Aconitine results in decreased expression of CDK5RAP2 protein CTD PMID:33236894 NCBI chr 4:70,135,092...70,328,672
Ensembl chr 4:70,135,093...70,328,680 		JBrowse link
G Cep170b centrosomal protein 170B increases expression ISO Aconitine results in increased expression of CEP170B protein CTD PMID:33236894 NCBI chr12:112,687,950...112,713,026
Ensembl chr12:112,686,889...112,713,026 		JBrowse link
G Cfhr1 complement factor H-related 1 increases expression ISO Aconitine results in increased expression of CFHR1 protein CTD PMID:33236894 NCBI chr 1:139,474,802...139,487,960
Ensembl chr 1:139,474,791...139,488,010 		JBrowse link
G Cfl1 cofilin 1, non-muscle decreases expression ISO Aconitine results in decreased expression of CFL1 protein CTD PMID:33236894 NCBI chr19:5,540,483...5,544,059
Ensembl chr19:5,540,483...5,545,229 		JBrowse link
G Cgn cingulin increases expression ISO Aconitine results in increased expression of CGN protein CTD PMID:33236894 NCBI chr 3:94,667,376...94,695,036
Ensembl chr 3:94,667,376...94,693,826 		JBrowse link
G Cirbp cold inducible RNA binding protein increases expression ISO Aconitine results in increased expression of CIRBP protein CTD PMID:33236894 NCBI chr10:80,001,824...80,008,620
Ensembl chr10:80,001,819...80,008,620 		JBrowse link
G Clec14a C-type lectin domain family 14, member a increases expression ISO Aconitine results in increased expression of CLEC14A protein CTD PMID:33236894 NCBI chr12:58,311,506...58,316,044
Ensembl chr12:58,311,506...58,316,076 		JBrowse link
G Clic1 chloride intracellular channel 1 decreases expression ISO Aconitine results in decreased expression of CLIC1 protein CTD PMID:33236894 NCBI chr17:35,269,219...35,277,695
Ensembl chr17:35,268,942...35,277,725 		JBrowse link
G Clta clathrin light chain A increases expression ISO Aconitine results in increased expression of CLTA protein CTD PMID:33236894 NCBI chr 4:44,003,816...44,032,846
Ensembl chr 4:44,004,452...44,032,846 		JBrowse link
G Col5a1 collagen, type V, alpha 1 increases expression ISO Aconitine results in increased expression of COL5A1 protein CTD PMID:33236894 NCBI chr 2:27,776,393...27,929,522
Ensembl chr 2:27,776,437...27,929,526 		JBrowse link
G Col5a2 collagen, type V, alpha 2 increases expression ISO Aconitine results in increased expression of COL5A2 protein CTD PMID:33236894 NCBI chr 1:45,413,491...45,542,442
Ensembl chr 1:45,413,481...45,542,442 		JBrowse link
G Commd9 COMM domain containing 9 increases expression ISO Aconitine results in increased expression of COMMD9 protein CTD PMID:33236894 NCBI chr 2:101,716,607...101,731,984
Ensembl chr 2:101,716,592...101,731,991 		JBrowse link
G Cope coatomer protein complex, subunit epsilon increases expression ISO Aconitine results in increased expression of COPE protein CTD PMID:33236894 NCBI chr 8:70,755,417...70,765,652
Ensembl chr 8:70,755,168...70,765,643 		JBrowse link
G Cops2 COP9 signalosome subunit 2 decreases expression ISO Aconitine results in decreased expression of COPS2 protein CTD PMID:33236894 NCBI chr 2:125,672,222...125,701,002
Ensembl chr 2:125,672,224...125,701,059 		JBrowse link
G Cops7a COP9 signalosome subunit 7A decreases expression ISO Aconitine results in decreased expression of COPS7A protein CTD PMID:33236894 NCBI chr 6:124,935,413...124,974,866
Ensembl chr 6:124,935,376...124,942,501 		JBrowse link
G Coq10a coenzyme Q10A decreases expression ISO Aconitine results in decreased expression of COQ10A protein CTD PMID:33236894 NCBI chr10:128,198,965...128,204,849
Ensembl chr10:128,198,969...128,204,866 		JBrowse link
G Cox15 cytochrome c oxidase assembly protein 15 decreases expression ISO Aconitine results in decreased expression of COX15 protein CTD PMID:33236894 NCBI chr19:43,721,693...43,741,439
Ensembl chr19:43,721,693...43,741,439 		JBrowse link
G Cox20 cytochrome c oxidase assembly protein 20 increases expression ISO Aconitine results in increased expression of COX20 protein CTD PMID:33236894 NCBI chr 1:178,146,379...178,150,258
Ensembl chr 1:178,146,695...178,150,258 		JBrowse link
G Cpne1 copine I increases expression ISO Aconitine results in increased expression of CPNE1 protein CTD PMID:33236894 NCBI chr 2:155,913,765...155,953,847
Ensembl chr 2:155,913,762...155,953,885 		JBrowse link
G Cr1l complement C3b/C4b receptor 1 like increases expression ISO Aconitine results in increased expression of CR1L protein CTD PMID:33236894 NCBI chr 1:194,781,019...194,813,878
Ensembl chr 1:194,779,690...194,813,894 		JBrowse link
G Crk v-crk avian sarcoma virus CT10 oncogene homolog increases expression ISO Aconitine results in increased expression of CRK protein CTD PMID:33236894 NCBI chr11:75,570,020...75,599,254
Ensembl chr11:75,570,085...75,597,734 		JBrowse link
G Crocc ciliary rootlet coiled-coil, rootletin decreases expression ISO Aconitine results in decreased expression of CROCC protein CTD PMID:33236894 NCBI chr 4:140,743,948...140,787,927
Ensembl chr 4:140,743,948...140,787,861 		JBrowse link
G Crppa CDP-L-ribitol pyrophosphorylase A decreases expression ISO Aconitine results in decreased expression of CRPPA protein CTD PMID:33236894 NCBI chr12:36,430,334...36,739,502
Ensembl chr12:36,431,449...36,739,502 		JBrowse link
G Csnk2a1 casein kinase 2, alpha 1 polypeptide increases expression
decreases expression		 ISO Aconitine results in increased expression of CSNK2A1 protein
Aconitine results in decreased expression of CSNK2A1 protein		 CTD PMID:32234357 PMID:33236894 NCBI chr 2:152,068,468...152,123,772
Ensembl chr 2:152,068,759...152,123,772 		JBrowse link
G Ctps1 cytidine 5'-triphosphate synthase 1 increases expression ISO Aconitine results in increased expression of CTPS1 protein CTD PMID:33236894 NCBI chr 4:120,397,065...120,427,473
Ensembl chr 4:120,397,065...120,427,473 		JBrowse link
G Ctsa cathepsin A increases expression ISO Aconitine results in increased expression of CTSA protein CTD PMID:33236894 NCBI chr 2:164,674,792...164,682,952
Ensembl chr 2:164,674,793...164,682,952 		JBrowse link
G Ctsc cathepsin C decreases expression ISO Aconitine results in decreased expression of CTSC protein CTD PMID:33236894 NCBI chr 7:87,927,233...87,960,083
Ensembl chr 7:87,927,293...87,960,096 		JBrowse link
G Cul1 cullin 1 increases expression ISO Aconitine results in increased expression of CUL1 protein CTD PMID:33236894 NCBI chr 6:47,430,516...47,503,078
Ensembl chr 6:47,430,332...47,503,073 		JBrowse link
G Cuta cutA divalent cation tolerance homolog increases expression ISO Aconitine results in increased expression of CUTA protein CTD PMID:33236894 NCBI chr17:27,156,946...27,158,847
Ensembl chr17:27,152,793...27,158,543 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO Aconitine results in decreased expression of CYP17A1 mRNA CTD PMID:31499053 NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [Fluvoxamine results in decreased activity of CYP1A2 protein] which results in increased chemical synthesis of Aconitine metabolite CTD PMID:21277363 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 increases metabolic processing
multiple interactions		 ISO CYP2C8 protein results in increased metabolism of Aconitine
[Gemfibrozil results in decreased activity of CYP2C8 protein] which affects the chemical synthesis of Aconitine metabolite		 CTD PMID:21277363 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157 		JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 multiple interactions ISO [Omeprazole results in decreased activity of CYP2C19 protein] which results in decreased chemical synthesis of Aconitine metabolite CTD PMID:21277363 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 multiple interactions
increases metabolic processing		 ISO [Amiodarone results in decreased activity of CYP2C9 protein] which results in decreased chemical synthesis of Aconitine metabolite; [CYP2C9 protein results in increased metabolism of Aconitine] which results in increased chemical synthesis of 16-O-demethylaconitine CTD PMID:21277363 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 increases metabolic processing
multiple interactions		 ISO CYP2D6 protein results in increased metabolism of Aconitine
[CYP2D6 protein results in increased metabolism of Aconitine] which results in increased chemical synthesis of 16-O-demethylaconitine; [Quinidine results in decreased activity of CYP2D6 protein] which results in decreased chemical synthesis of Aconitine metabolite		 CTD PMID:21277363 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 multiple interactions
increases metabolic processing
increases expression		 ISO [Aconitine co-treated with mesaconitine co-treated with hypaconitine] results in increased expression of CYP3A4 mRNA; [CYP3A4 protein results in increased metabolism of Aconitine] which results in increased chemical synthesis of 16-O-demethylaconitine
Aconitine results in increased expression of CYP3A4 mRNA		 CTD PMID:21277363 PMID:30303438 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 multiple interactions
increases metabolic processing		 ISO [CYP3A5 protein results in increased metabolism of Aconitine] which results in increased chemical synthesis of 16-O-demethylaconitine CTD PMID:21277363 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Dap death-associated protein increases expression ISO Aconitine results in increased expression of DAP protein CTD PMID:33236894 NCBI chr15:31,224,531...31,274,484
Ensembl chr15:31,224,460...31,274,487 		JBrowse link
G Dcakd dephospho-CoA kinase domain containing increases expression ISO Aconitine results in increased expression of DCAKD protein CTD PMID:33236894 NCBI chr11:102,884,873...102,919,107
Ensembl chr11:102,884,873...102,919,159 		JBrowse link
G Dctn5 dynactin 5 decreases expression ISO Aconitine results in decreased expression of DCTN5 protein CTD PMID:33236894 NCBI chr 7:121,732,264...121,748,267
Ensembl chr 7:121,732,264...121,748,267 		JBrowse link
G Ddx39b DEAD box helicase 39b decreases expression ISO Aconitine results in decreased expression of DDX39B protein CTD PMID:33236894 NCBI chr17:35,460,722...35,472,683
Ensembl chr17:35,460,722...35,472,683 		JBrowse link
G Ddx3y DEAD box helicase 3, Y-linked increases expression ISO Aconitine results in increased expression of DDX3Y protein CTD PMID:33236894 NCBI chr  Y:1,260,715...1,286,630
Ensembl chr  Y:1,260,771...1,286,629 		JBrowse link
G Dera deoxyribose-phosphate aldolase increases expression ISO Aconitine results in increased expression of DERA protein CTD PMID:33236894 NCBI chr 6:137,731,093...137,814,894
Ensembl chr 6:137,731,544...137,834,338 		JBrowse link
G Dhrs7c dehydrogenase/reductase 7C decreases expression ISO Aconitine results in decreased expression of DHRS7C protein CTD PMID:33236894 NCBI chr11:67,689,097...67,706,828
Ensembl chr11:67,689,013...67,706,828 		JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 increases expression ISO Aconitine results in increased expression of DLG5 protein CTD PMID:33236894 NCBI chr14:24,184,021...24,295,988
Ensembl chr14:24,184,021...24,295,988 		JBrowse link
G Dmac2l distal membrane arm assembly component 2 like decreases expression ISO Aconitine results in decreased expression of DMAC2L protein CTD PMID:33236894 NCBI chr12:69,771,687...69,791,439
Ensembl chr12:69,771,724...69,791,434 		JBrowse link
G Dnah12 dynein, axonemal, heavy chain 12 increases expression ISO Aconitine results in increased expression of DNAH12 protein CTD PMID:33236894 NCBI chr14:26,412,709...26,614,250
Ensembl chr14:26,414,429...26,613,660 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 increases expression ISO Aconitine results in increased expression of DNAJA1 protein CTD PMID:33236894 NCBI chr 4:40,722,468...40,734,965
Ensembl chr 4:40,722,150...40,737,149 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Aconitine results in increased expression of DNAJB4 protein CTD PMID:33236894 NCBI chr 3:151,887,217...151,915,720
Ensembl chr 3:151,884,148...151,915,939 		JBrowse link
G Dnajc16 DnaJ heat shock protein family (Hsp40) member C16 increases expression ISO Aconitine results in increased expression of DNAJC16 protein CTD PMID:33236894 NCBI chr 4:141,487,498...141,518,255
Ensembl chr 4:141,487,500...141,518,242 		JBrowse link
G Dnajc30 DnaJ heat shock protein family (Hsp40) member C30 increases expression ISO Aconitine results in increased expression of DNAJC30 protein CTD PMID:33236894 NCBI chr 5:135,093,060...135,094,219
Ensembl chr 5:135,093,056...135,094,716 		JBrowse link
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 decreases expression ISO Aconitine results in decreased expression of DNAJC5 protein CTD PMID:33236894 NCBI chr 2:181,162,141...181,194,679
Ensembl chr 2:181,162,278...181,196,926 		JBrowse link
G Dnm1l dynamin 1-like increases phosphorylation ISO Aconitine results in increased phosphorylation of DNM1L protein CTD PMID:33945864 NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823 		JBrowse link
G Dok4 docking protein 4 increases expression ISO Aconitine results in increased expression of DOK4 protein CTD PMID:33236894 NCBI chr 8:95,590,456...95,602,940
Ensembl chr 8:95,590,456...95,602,958 		JBrowse link
G Dpm1 dolichyl-phosphate mannosyltransferase subunit 1, catalytic decreases expression ISO Aconitine results in decreased expression of DPM1 protein CTD PMID:33236894 NCBI chr 2:168,050,968...168,072,299
Ensembl chr 2:168,050,968...168,072,511 		JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 decreases expression ISO Aconitine results in decreased expression of DPYSL3 protein CTD PMID:33236894 NCBI chr18:43,454,044...43,571,354
Ensembl chr18:43,454,049...43,571,351 		JBrowse link
G Dync1i2 dynein cytoplasmic 1 intermediate chain 2 decreases expression ISO Aconitine results in decreased expression of DYNC1I2 protein CTD PMID:33236894 NCBI chr 2:71,041,999...71,093,647
Ensembl chr 2:71,042,050...71,093,647 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression ISO Aconitine results in decreased expression of DYNLL1 protein CTD PMID:33236894 NCBI chr 5:115,435,129...115,438,995
Ensembl chr 5:115,435,169...115,439,058 		JBrowse link
G Efr3a EFR3 homolog A decreases expression ISO Aconitine results in decreased expression of EFR3A protein CTD PMID:33236894 NCBI chr15:65,658,852...65,745,661
Ensembl chr15:65,658,883...65,745,665 		JBrowse link
G Ehhadh enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase increases expression ISO Aconitine results in increased expression of EHHADH protein CTD PMID:33236894 NCBI chr16:21,580,035...21,606,589
Ensembl chr16:21,580,037...21,606,557 		JBrowse link
G Eif2s3x eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked increases expression ISO Aconitine results in increased expression of EIF2S3 protein CTD PMID:33236894 NCBI chr  X:93,232,315...93,256,257
Ensembl chr  X:93,232,313...93,256,468 		JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression ISO Aconitine results in decreased expression of EIF4A2 protein CTD PMID:33236894 NCBI chr16:22,924,846...22,932,882
Ensembl chr16:22,926,194...22,932,886 		JBrowse link
G Elac2 elaC ribonuclease Z 2 decreases expression ISO Aconitine results in decreased expression of ELAC2 protein CTD PMID:33236894 NCBI chr11:64,869,856...64,892,906
Ensembl chr11:64,869,864...64,892,895 		JBrowse link
G Eloc elongin C decreases expression ISO Aconitine results in decreased expression of ELOC protein CTD PMID:33236894 NCBI chr 1:16,711,949...16,727,652
Ensembl chr 1:16,711,949...16,727,266 		JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 decreases expression ISO Aconitine results in decreased expression of ENTPD2 protein CTD PMID:33236894 NCBI chr 2:25,285,886...25,291,335
Ensembl chr 2:25,285,886...25,291,333 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions
affects expression		 ISO crenigacestat affects the reaction [Aconitine affects the expression of EP300 protein] CTD PMID:32234357 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Epb42 erythrocyte membrane protein band 4.2 increases expression ISO Aconitine results in increased expression of EPB42 protein CTD PMID:33236894 NCBI chr 2:120,848,372...120,867,358
Ensembl chr 2:120,848,372...120,867,553 		JBrowse link
G Epm2a epilepsy, progressive myoclonic epilepsy, type 2 gene alpha increases expression ISO Aconitine results in increased expression of EPM2A protein CTD PMID:33236894 NCBI chr10:11,218,435...11,335,408
Ensembl chr10:11,219,148...11,335,388 		JBrowse link
G Eps15l1 epidermal growth factor receptor pathway substrate 15-like 1 increases expression ISO Aconitine results in increased expression of EPS15L1 protein CTD PMID:33236894 NCBI chr 8:73,094,834...73,175,410
Ensembl chr 8:73,094,839...73,175,304 		JBrowse link
G Esam endothelial cell-specific adhesion molecule increases expression ISO Aconitine results in increased expression of ESAM protein CTD PMID:33236894 NCBI chr 9:37,439,385...37,449,615
Ensembl chr 9:37,439,374...37,449,615 		JBrowse link
G Exoc8 exocyst complex component 8 decreases expression ISO Aconitine results in decreased expression of EXOC8 protein CTD PMID:33236894 NCBI chr 8:125,617,038...125,624,444
Ensembl chr 8:125,619,847...125,624,444 		JBrowse link
G Fabp3 fatty acid binding protein 3, muscle and heart increases expression ISO Aconitine results in increased expression of FABP3 protein CTD PMID:33236894 NCBI chr 4:130,202,531...130,209,256
Ensembl chr 4:130,202,388...130,209,256 		JBrowse link
G Fadd Fas associated via death domain increases expression ISO
EXP		 Aconitine results in increased expression of FADD protein CTD PMID:33236894 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200 		JBrowse link
G Faf2 Fas associated factor family member 2 increases expression ISO Aconitine results in increased expression of FAF2 protein CTD PMID:33236894 NCBI chr13:54,769,597...54,811,876
Ensembl chr13:54,769,597...54,811,876 		JBrowse link
G Fam162a family with sequence similarity 162, member A decreases expression ISO Aconitine results in decreased expression of FAM162A protein CTD PMID:33236894 NCBI chr16:35,864,214...35,891,931
Ensembl chr16:35,864,131...35,891,964 		JBrowse link
G Fat3 FAT atypical cadherin 3 increases expression ISO Aconitine results in increased expression of FAT3 protein CTD PMID:33236894 NCBI chr 9:15,821,485...16,413,981
Ensembl chr 9:15,821,485...16,412,581 		JBrowse link
G Fbln5 fibulin 5 increases expression ISO Aconitine results in increased expression of FBLN5 protein CTD PMID:33236894 NCBI chr12:101,712,820...101,785,541
Ensembl chr12:101,712,824...101,785,314 		JBrowse link
G Fdx1 ferredoxin 1 increases expression ISO Aconitine results in increased expression of FDX1 protein CTD PMID:33236894 NCBI chr 9:51,854,323...51,874,902
Ensembl chr 9:51,854,606...51,874,856 		JBrowse link
G Fhod3 formin homology 2 domain containing 3 increases expression ISO Aconitine results in increased expression of FHOD3 protein CTD PMID:33236894 NCBI chr18:24,841,445...25,266,564
Ensembl chr18:24,841,680...25,266,558 		JBrowse link
G Fitm2 fat storage-inducing transmembrane protein 2 decreases expression ISO Aconitine results in decreased expression of FITM2 protein CTD PMID:33236894 NCBI chr 2:163,310,623...163,314,549
Ensembl chr 2:163,308,299...163,314,549 		JBrowse link
G Fkbp10 FK506 binding protein 10 decreases expression ISO Aconitine results in decreased expression of FKBP10 protein CTD PMID:33236894 NCBI chr11:100,306,520...100,315,666
Ensembl chr11:100,306,523...100,315,650 		JBrowse link
G Flot1 flotillin 1 increases expression ISO Aconitine results in increased expression of FLOT1 protein CTD PMID:33236894 NCBI chr17:36,134,243...36,143,674
Ensembl chr17:36,134,122...36,143,683 		JBrowse link
G Fn1 fibronectin 1 increases expression ISO Aconitine results in increased expression of FN1 protein CTD PMID:33236894 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359 		JBrowse link
G Fto FTO alpha-ketoglutarate dependent dioxygenase increases expression ISO Aconitine results in increased expression of FTO protein CTD PMID:33236894 NCBI chr 8:92,039,995...92,395,061
Ensembl chr 8:92,040,153...92,395,067 		JBrowse link
G Fundc2 FUN14 domain containing 2 decreases expression ISO Aconitine results in decreased expression of FUNDC2 protein CTD PMID:33236894 NCBI chr  X:74,426,005...74,440,764
Ensembl chr  X:74,426,005...74,440,065 		JBrowse link
G Gar1 GAR1 ribonucleoprotein increases expression ISO Aconitine results in increased expression of GAR1 protein CTD PMID:33236894 NCBI chr 3:129,618,561...129,625,045
Ensembl chr 3:129,618,561...129,625,045 		JBrowse link
G Gbp2 guanylate binding protein 2 decreases expression ISO Aconitine results in decreased expression of GBP2 protein CTD PMID:33236894 NCBI chr 3:142,326,424...142,343,769
Ensembl chr 3:142,326,363...142,343,769 		JBrowse link
G Gbp2b guanylate binding protein 2b decreases expression ISO Aconitine results in decreased expression of GBP1 protein CTD PMID:33236894 NCBI chr 3:142,300,577...142,324,940
Ensembl chr 3:142,300,608...142,324,940 		JBrowse link
G Gck glucokinase increases expression ISO Aconitine results in increased expression of GCK protein CTD PMID:33236894 NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081 		JBrowse link
G Glrx5 glutaredoxin 5 increases expression ISO Aconitine results in increased expression of GLRX5 protein CTD PMID:33236894 NCBI chr12:104,998,877...105,007,170
Ensembl chr12:104,998,947...105,009,165 		JBrowse link
G Gmpr guanosine monophosphate reductase decreases expression ISO Aconitine results in decreased expression of GMPR protein CTD PMID:33236894 NCBI chr13:45,660,905...45,699,862
Ensembl chr13:45,660,920...45,707,276 		JBrowse link
G Gna13 guanine nucleotide binding protein, alpha 13 increases expression ISO Aconitine results in increased expression of GNA13 protein CTD PMID:33236894 NCBI chr11:109,253,620...109,292,195
Ensembl chr11:109,253,657...109,292,195 		JBrowse link
G Gnb3 guanine nucleotide binding protein (G protein), beta 3 decreases expression ISO Aconitine results in decreased expression of GNB3 protein CTD PMID:33236894 NCBI chr 6:124,811,203...124,817,238
Ensembl chr 6:124,811,203...124,817,238 		JBrowse link
G Golgb1 golgin B1 increases expression ISO Aconitine results in increased expression of GOLGB1 protein CTD PMID:33236894 NCBI chr16:36,695,455...36,753,447
Ensembl chr16:36,695,502...36,753,447 		JBrowse link
G Grsf1 G-rich RNA sequence binding factor 1 increases expression ISO Aconitine results in increased expression of GRSF1 protein CTD PMID:33236894 NCBI chr 5:88,807,092...88,824,030
Ensembl chr 5:88,807,307...88,824,030 		JBrowse link
G Gucy1b1 guanylate cyclase 1, soluble, beta 1 increases expression ISO Aconitine results in increased expression of GUCY1B1 protein CTD PMID:33236894 NCBI chr 3:81,939,311...81,982,018
Ensembl chr 3:81,939,313...81,981,996 		JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO Aconitine results in increased expression of H1F2 protein CTD PMID:33236894 NCBI chr13:23,922,790...23,923,514
Ensembl chr13:23,922,791...23,924,350 		JBrowse link
G H1f3 H1.3 linker histone, cluster member increases expression ISO Aconitine results in increased expression of H4F3 protein CTD PMID:33236894 NCBI chr13:23,739,206...23,739,981
Ensembl chr13:23,737,436...23,744,860 		JBrowse link
G H1f4 H1.4 linker histone, cluster member increases expression ISO Aconitine results in increased expression of H1-4 protein CTD PMID:33236894 NCBI chr13:23,805,760...23,806,541
Ensembl chr13:23,804,612...23,806,541 		JBrowse link
G H2-T23 histocompatibility 2, T region locus 23 decreases expression ISO Aconitine results in decreased expression of RT1-A2 protein CTD PMID:33236894 NCBI chr17:36,340,869...36,343,593
Ensembl chr17:36,340,665...36,343,747 		JBrowse link
G H2bc27 H2B clustered histone 27 increases expression ISO Aconitine results in increased expression of H2BC26 protein CTD PMID:33236894 NCBI chr11:58,839,737...58,840,198
Ensembl chr11:58,839,746...58,840,359 		JBrowse link
G Hacd1 3-hydroxyacyl-CoA dehydratase 1 increases expression ISO Aconitine results in increased expression of HACD1 protein CTD PMID:33236894 NCBI chr 2:14,031,642...14,060,846
Ensembl chr 2:13,855,093...14,060,847 		JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 increases expression ISO Aconitine results in increased expression of HACL1 protein CTD PMID:33236894 NCBI chr14:31,329,183...31,364,201
Ensembl chr14:31,320,687...31,363,243 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 increases expression ISO Aconitine results in increased expression of HBA-A2 protein; Aconitine results in increased expression of HBA1 protein CTD PMID:33236894 NCBI chr11:32,246,492...32,247,310
Ensembl chr11:32,246,489...32,247,298 		JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain decreases expression ISO Aconitine results in decreased expression of HBB protein CTD PMID:33236894
G Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 multiple interactions
increases expression
affects expression		 ISO Aconitine affects the reaction [NOTCH1 protein modified form binds to HCN4 promoter]; crenigacestat affects the reaction [Aconitine affects the expression of HCN4 protein]
Aconitine promotes the reaction [NOTCH1 protein modified form binds to HCN4 promoter]
Aconitine results in increased expression of HCN4 mRNA
Aconitine affects the expression of HCN4 mRNA; Aconitine affects the expression of HCN4 protein		 CTD PMID:32234357 NCBI chr 9:58,730,232...58,770,458
Ensembl chr 9:58,730,695...58,770,458 		JBrowse link
G Hdac2 histone deacetylase 2 decreases expression ISO Aconitine results in decreased expression of HDAC2 protein CTD PMID:33236894 NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885 		JBrowse link
G Hdgfl3 HDGF like 3 increases expression ISO Aconitine results in increased expression of HDGFL3 protein CTD PMID:33236894 NCBI chr 7:81,531,004...81,587,227
Ensembl chr 7:81,530,999...81,584,221 		JBrowse link
G Hebp1 heme binding protein 1 increases expression ISO Aconitine results in increased expression of HEBP1 protein CTD PMID:33236894 NCBI chr 6:135,114,517...135,145,213
Ensembl chr 6:135,114,520...135,175,020 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases expression
multiple interactions		 ISO Aconitine results in increased expression of HES1 protein
crenigacestat inhibits the reaction [Aconitine results in increased expression of HES1 protein]		 CTD PMID:32234357 NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614 		JBrowse link
G Hhatl hedgehog acyltransferase-like decreases expression ISO Aconitine results in decreased expression of HHATL protein CTD PMID:33236894 NCBI chr 9:121,613,082...121,626,604
Ensembl chr 9:121,613,082...121,621,573 		JBrowse link
G Hk1 hexokinase 1 decreases expression ISO Aconitine results in decreased expression of HK1 protein CTD PMID:33236894 NCBI chr10:62,104,634...62,215,699
Ensembl chr10:62,104,634...62,215,687 		JBrowse link
G Hmbs hydroxymethylbilane synthase decreases expression ISO Aconitine results in decreased expression of HMBS protein CTD PMID:33236894 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525 		JBrowse link
G Hnrnpll heterogeneous nuclear ribonucleoprotein L-like increases expression ISO Aconitine results in increased expression of HNRNPLL protein CTD PMID:33236894 NCBI chr17:80,336,916...80,369,697
Ensembl chr17:80,336,916...80,369,697 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U increases expression ISO Aconitine results in increased expression of HNRNPU protein CTD PMID:33236894 NCBI chr 1:178,148,673...178,170,063
Ensembl chr 1:178,148,673...178,165,362 		JBrowse link
G Hpdl 4-hydroxyphenylpyruvate dioxygenase-like increases expression ISO Aconitine results in increased expression of HPDL protein CTD PMID:33236894 NCBI chr 4:116,677,104...116,678,705
Ensembl chr 4:116,677,101...116,678,904 		JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 increases expression ISO Aconitine results in increased expression of HSD17B11 protein CTD PMID:33236894 NCBI chr 5:104,137,631...104,169,662
Ensembl chr 5:104,137,628...104,169,785 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression ISO Aconitine results in decreased expression of HSD17B3 mRNA CTD PMID:31499053 NCBI chr13:64,206,088...64,237,076
Ensembl chr13:64,206,080...64,237,044 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 increases expression ISO Aconitine results in increased expression of HSD17B4 protein CTD PMID:33236894 NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO Aconitine results in decreased expression of HSD3B1 mRNA CTD PMID:31499053 NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110 		JBrowse link
G Hspa4l heat shock protein 4 like increases expression ISO Aconitine results in increased expression of HSPA4L protein CTD PMID:33236894 NCBI chr 3:40,698,664...40,750,538
Ensembl chr 3:40,699,814...40,750,538 		JBrowse link
G Iah1 isoamyl acetate-hydrolyzing esterase 1 homolog decreases expression ISO Aconitine results in decreased expression of IAH1 protein CTD PMID:33236894 NCBI chr12:21,366,363...21,373,608
Ensembl chr12:21,366,390...21,373,820 		JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 decreases expression ISO Aconitine results in decreased expression of IARS1 protein CTD PMID:33236894 NCBI chr13:49,835,606...49,887,743
Ensembl chr13:49,835,576...49,887,743 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO Aconitine results in decreased expression of IFIT3 protein CTD PMID:33236894 NCBI chr19:34,560,519...34,566,382
Ensembl chr19:34,560,931...34,566,131 		JBrowse link
G Il18 interleukin 18 multiple interactions
increases expression		 ISO
EXP		 NLRP3 protein affects the reaction [Aconitine results in increased expression of IL18 protein]; NOD1 protein affects the reaction [Aconitine results in increased expression of IL18 protein]; NOD2 protein affects the reaction [Aconitine results in increased expression of IL18 protein] CTD PMID:33236894 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 EXP
ISO		 Aconitine results in increased expression of IL1B protein
NLRP3 protein affects the reaction [Aconitine results in increased expression of IL1B protein]; NOD1 protein affects the reaction [Aconitine results in increased expression of IL1B protein]; NOD2 protein affects the reaction [Aconitine results in increased expression of IL1B protein]		 CTD PMID:33236894 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Ilf3 interleukin enhancer binding factor 3 increases expression ISO Aconitine results in increased expression of ILF3 protein CTD PMID:33236894 NCBI chr 9:21,278,964...21,316,659
Ensembl chr 9:21,279,167...21,316,657 		JBrowse link
G Inpp5a inositol polyphosphate-5-phosphatase A decreases expression ISO Aconitine results in decreased expression of INPP5A protein CTD PMID:33236894 NCBI chr 7:138,969,025...139,159,568
Ensembl chr 7:138,969,025...139,159,568 		JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 increases expression ISO Aconitine results in increased expression of INPPL1 protein CTD PMID:33236894 NCBI chr 7:101,471,839...101,487,419
Ensembl chr 7:101,471,839...101,487,436 		JBrowse link
G Jam3 junction adhesion molecule 3 decreases expression ISO Aconitine results in decreased expression of JAM3 protein CTD PMID:33236894 NCBI chr 9:27,008,680...27,066,739
Ensembl chr 9:27,008,680...27,066,717 		JBrowse link
G Jph1 junctophilin 1 decreases expression ISO Aconitine results in decreased expression of JPH1 protein CTD PMID:33236894 NCBI chr 1:17,012,328...17,168,132
Ensembl chr 1:17,034,784...17,168,113 		JBrowse link
G Kdm5a lysine demethylase 5A multiple interactions
increases expression		 ISO Aconitine promotes the reaction [NOTCH1 protein modified form binds to KDM5A protein]; crenigacestat inhibits the reaction [Aconitine results in increased expression of KDM5A protein] CTD PMID:32234357 NCBI chr 6:120,341,060...120,421,535
Ensembl chr 6:120,341,085...120,421,535 		JBrowse link
G Khdrbs3 KH domain containing, RNA binding, signal transduction associated 3 increases expression ISO Aconitine results in increased expression of KHDRBS3 protein CTD PMID:33236894 NCBI chr15:68,800,155...68,973,064
Ensembl chr15:68,800,269...68,973,060 		JBrowse link
G Kin Kin17 DNA and RNA binding protein increases expression ISO Aconitine results in increased expression of KIN protein CTD PMID:33236894 NCBI chr 2:10,085,397...10,097,512
Ensembl chr 2:10,085,404...10,097,617 		JBrowse link
G Klhl29 kelch-like 29 increases expression ISO Aconitine results in increased expression of KLHL29 protein CTD PMID:33236894 NCBI chr12:5,127,465...5,425,682
Ensembl chr12:5,127,472...5,425,682 		JBrowse link
G Klkb1 kallikrein B, plasma 1 decreases expression ISO Aconitine results in decreased expression of KLKB1 protein CTD PMID:33236894 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896 		JBrowse link
G Kng1 kininogen 1 increases expression ISO Aconitine results in increased expression of KNG1 protein CTD PMID:33236894 NCBI chr16:22,876,970...22,900,828
Ensembl chr16:22,876,615...22,900,828 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 increases expression ISO Aconitine results in increased expression of LAMP1 protein CTD PMID:33236894 NCBI chr 8:13,209,161...13,225,338
Ensembl chr 8:13,209,161...13,225,338 		JBrowse link
G Ldha lactate dehydrogenase A decreases expression ISO Aconitine results in decreased expression of LDHA protein CTD PMID:33236894 NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051 		JBrowse link
G Lgmn legumain decreases expression ISO Aconitine results in decreased expression of LGMN protein CTD PMID:33236894 NCBI chr12:102,360,341...102,405,987
Ensembl chr12:102,360,343...102,406,072 		JBrowse link
G Lgsn lengsin, lens protein with glutamine synthetase domain decreases expression ISO Aconitine results in decreased expression of LGSN protein CTD PMID:33236894 NCBI chr 1:31,215,362...31,243,806
Ensembl chr 1:31,215,482...31,243,806 		JBrowse link
G Lims1 LIM and senescent cell antigen-like domains 1 decreases expression ISO Aconitine results in decreased expression of LIMS1 protein CTD PMID:33236894 NCBI chr10:58,159,164...58,260,513
Ensembl chr10:58,159,288...58,260,513 		JBrowse link
G Lpl lipoprotein lipase increases expression ISO Aconitine results in increased expression of LPL protein CTD PMID:33236894 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100 		JBrowse link
G Lrpprc leucine-rich PPR-motif containing increases expression ISO Aconitine results in increased expression of LRPPRC protein CTD PMID:33236894 NCBI chr17:85,012,675...85,098,214
Ensembl chr17:85,012,675...85,098,217 		JBrowse link
G Lrriq3 leucine-rich repeats and IQ motif containing 3 increases expression ISO Aconitine results in increased expression of LRRIQ3 protein CTD PMID:33236894 NCBI chr 3:154,799,032...154,899,915
Ensembl chr 3:154,799,071...154,899,917 		JBrowse link
G Lrrn4 leucine rich repeat neuronal 4 increases expression ISO Aconitine results in increased expression of LRRN4 protein CTD PMID:33236894 NCBI chr 2:132,710,436...132,735,930
Ensembl chr 2:132,710,225...132,722,811 		JBrowse link
G Luc7l3 LUC7-like 3 (S. cerevisiae) increases expression ISO Aconitine results in increased expression of LUC7L3 protein CTD PMID:33236894 NCBI chr11:94,181,899...94,213,196
Ensembl chr11:94,178,716...94,212,814 		JBrowse link
G Luzp1 leucine zipper protein 1 decreases expression ISO Aconitine results in decreased expression of LUZP1 protein CTD PMID:33236894 NCBI chr 4:136,189,892...136,282,036
Ensembl chr 4:136,197,072...136,282,091 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E decreases expression ISO Aconitine results in decreased expression of LY6E protein CTD PMID:33236894 NCBI chr15:74,826,874...74,831,753
Ensembl chr15:74,826,900...74,831,752 		JBrowse link
G Lyrm2 LYR motif containing 2 increases expression ISO Aconitine results in increased expression of LYRM2 protein CTD PMID:33236894 NCBI chr 4:32,800,259...32,802,268
Ensembl chr 4:32,800,253...32,801,559 		JBrowse link
G Lyz2 lysozyme 2 increases expression ISO Aconitine results in increased expression of LYZ2 protein CTD PMID:33236894 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Magohb mago homolog B, exon junction complex core component decreases expression ISO Aconitine results in decreased expression of MAGOHB protein CTD PMID:33236894 NCBI chr 6:131,261,351...131,270,207
Ensembl chr 6:131,261,351...131,270,207 		JBrowse link
G Maip1 matrix AAA peptidase interacting protein 1 decreases expression ISO Aconitine results in decreased expression of MAIP1 protein CTD PMID:33236894 NCBI chr 1:57,445,425...57,457,112
Ensembl chr 1:57,445,487...57,457,112 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 increases expression ISO Aconitine results in increased expression of MAP4K4 protein CTD PMID:33236894 NCBI chr 1:39,939,806...40,065,470
Ensembl chr 1:39,940,073...40,065,470 		JBrowse link
G Map7d1 MAP7 domain containing 1 increases expression ISO Aconitine results in increased expression of MAP7D1 protein CTD PMID:33236894 NCBI chr 4:126,125,960...126,150,112
Ensembl chr 4:126,125,960...126,150,136 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO Aconitine results in increased expression of and results in increased phosphorylation of MAPK1 protein CTD PMID:24840785 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO Aconitine results in increased expression of and results in increased phosphorylation of MAPK3 protein CTD PMID:24840785 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mcat malonyl CoA:ACP acyltransferase (mitochondrial) increases expression ISO Aconitine results in increased expression of MCAT protein CTD PMID:33236894 NCBI chr15:83,430,998...83,439,936
Ensembl chr15:83,430,998...83,447,988 		JBrowse link
G Mcu mitochondrial calcium uniporter increases expression
multiple interactions		 ISO
EXP		 Aconitine results in increased expression of MCU protein
[Aconitine co-treated with Ruthenium Red] results in increased expression of MCU protein; [Aconitine co-treated with Spermine] results in increased expression of MCU protein		 CTD PMID:33236894 PMID:37506855 NCBI chr10:59,282,806...59,453,231
Ensembl chr10:59,282,806...59,452,514 		JBrowse link
G Mfap2 microfibrillar-associated protein 2 increases expression ISO Aconitine results in increased expression of MFAP2 protein CTD PMID:33236894 NCBI chr 4:140,737,735...140,743,284
Ensembl chr 4:140,737,729...140,743,295 		JBrowse link
G Mff mitochondrial fission factor increases phosphorylation ISO Aconitine results in increased phosphorylation of MFF protein CTD PMID:33945864 NCBI chr 1:82,702,599...82,730,111
Ensembl chr 1:82,702,611...82,730,115 		JBrowse link
G Mfn1 mitofusin 1 decreases expression ISO Aconitine results in decreased expression of MFN1 protein CTD PMID:33945864 NCBI chr 3:32,583,594...32,633,384
Ensembl chr 3:32,583,614...32,633,388 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases expression ISO Aconitine results in decreased expression of MGST1 protein CTD PMID:33236894 NCBI chr 6:138,117,525...138,133,753
Ensembl chr 6:138,117,314...138,133,753 		JBrowse link
G Micos10 mitochondrial contact site and cristae organizing system subunit 10 increases expression ISO Aconitine results in increased expression of MICOS10 protein CTD PMID:33236894 NCBI chr 4:138,829,125...138,858,667
Ensembl chr 4:138,829,125...138,858,424 		JBrowse link
G Mob4 MOB family member 4, phocein increases expression ISO Aconitine results in increased expression of MOB4 protein CTD PMID:33236894 NCBI chr 1:55,170,404...55,194,058
Ensembl chr 1:55,170,390...55,194,058 		JBrowse link
G Mrpl13 mitochondrial ribosomal protein L13 increases expression ISO Aconitine results in increased expression of MRPL13 protein CTD PMID:33236894 NCBI chr15:55,397,491...55,420,708
Ensembl chr15:55,397,490...55,421,144 		JBrowse link
G Mrpl20 mitochondrial ribosomal protein L20 increases expression ISO Aconitine results in increased expression of MRPL20 protein CTD PMID:33236894 NCBI chr 4:155,887,335...155,893,288
Ensembl chr 4:155,887,335...155,894,432 		JBrowse link
G Mrpl22 mitochondrial ribosomal protein L22 decreases expression ISO Aconitine results in decreased expression of MRPL22 protein CTD PMID:33236894 NCBI chr11:58,060,850...58,070,406
Ensembl chr11:58,062,487...58,070,391 		JBrowse link
G Mrpl37 mitochondrial ribosomal protein L37 decreases expression ISO Aconitine results in decreased expression of MRPL37 protein CTD PMID:33236894 NCBI chr 4:106,913,071...106,924,063
Ensembl chr 4:106,913,071...106,924,065 		JBrowse link
G Mrpl40 mitochondrial ribosomal protein L40 decreases expression ISO Aconitine results in decreased expression of MRPL40 protein CTD PMID:33236894 NCBI chr16:18,690,767...18,695,875
Ensembl chr16:18,690,768...18,695,612 		JBrowse link
G Mrpl46 mitochondrial ribosomal protein L46 decreases expression ISO Aconitine results in decreased expression of MRPL46 protein CTD PMID:33236894 NCBI chr 7:78,425,089...78,432,837
Ensembl chr 7:78,424,984...78,433,279 		JBrowse link
G Mrps10 mitochondrial ribosomal protein S10 decreases expression ISO Aconitine results in decreased expression of MRPS10 protein CTD PMID:33236894 NCBI chr17:47,679,803...47,692,343
Ensembl chr17:47,679,812...47,692,342 		JBrowse link
G Mrps22 mitochondrial ribosomal protein S22 decreases expression ISO Aconitine results in decreased expression of MRPS22 protein CTD PMID:33236894 NCBI chr 9:98,470,783...98,483,732
Ensembl chr 9:98,470,783...98,483,713 		JBrowse link
G Mrps33 mitochondrial ribosomal protein S33 decreases expression ISO Aconitine results in decreased expression of MRPS33 protein CTD PMID:33236894 NCBI chr 6:39,778,738...39,787,870
Ensembl chr 6:39,778,738...39,787,922 		JBrowse link
G Mrps7 mitchondrial ribosomal protein S7 increases expression ISO Aconitine results in increased expression of MRPS7 protein CTD PMID:33236894 NCBI chr11:115,494,966...115,498,862
Ensembl chr11:115,494,751...115,498,862 		JBrowse link
G mt-Nd1 NADH dehydrogenase 1, mitochondrial decreases expression ISO Aconitine results in decreased expression of ND1 protein CTD PMID:33236894 NCBI chr MT:2,751...3,707
Ensembl chr MT:2,751...3,707 		JBrowse link
G mt-Nd3 NADH dehydrogenase 3, mitochondrial decreases expression ISO Aconitine results in decreased expression of ND3 protein CTD PMID:33236894 NCBI chr MT:9,459...9,806
Ensembl chr MT:9,459...9,806 		JBrowse link
G mt-Nd4l NADH dehydrogenase 4L, mitochondrial decreases expression ISO Aconitine results in decreased expression of ND4L protein CTD PMID:33236894 NCBI chr MT:9,877...10,173
Ensembl chr MT:9,877...10,173 		JBrowse link
G mt-Nd5 NADH dehydrogenase 5, mitochondrial decreases expression ISO Aconitine results in decreased expression of ND5 protein CTD PMID:33236894 NCBI chr MT:11,742...13,565
Ensembl chr MT:11,742...13,565 		JBrowse link
G Mt1 metallothionein 1 increases expression ISO Aconitine results in increased expression of MT1M protein CTD PMID:33236894 NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955 		JBrowse link
G Mtch2 mitochondrial carrier 2 decreases expression ISO Aconitine results in decreased expression of MTCH2 protein CTD PMID:33236894 NCBI chr 2:90,677,434...90,697,154
Ensembl chr 2:90,677,499...90,697,154 		JBrowse link
G Mtf2 metal response element binding transcription factor 2 increases expression ISO Aconitine results in increased expression of MTF2 protein CTD PMID:33236894 NCBI chr 5:108,213,518...108,257,085
Ensembl chr 5:108,213,540...108,256,870 		JBrowse link
G Mtif2 mitochondrial translational initiation factor 2 decreases expression ISO Aconitine results in decreased expression of MTIF2 protein CTD PMID:33236894 NCBI chr11:29,475,352...29,495,452
Ensembl chr11:29,476,408...29,495,279 		JBrowse link
G Mtmr2 myotubularin related protein 2 decreases expression ISO Aconitine results in decreased expression of MTMR2 protein CTD PMID:33236894 NCBI chr 9:13,660,397...13,720,192
Ensembl chr 9:13,659,706...13,717,777 		JBrowse link
G Myc myelocytomatosis oncogene increases expression ISO Aconitine results in increased expression of MYC protein CTD PMID:32234357 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Myg1 melanocyte proliferating gene 1 decreases expression ISO Aconitine results in decreased expression of MYG1 protein CTD PMID:33236894 NCBI chr15:102,240,144...102,246,574
Ensembl chr15:102,240,144...102,246,574 		JBrowse link
G Myh1 myosin, heavy polypeptide 1, skeletal muscle, adult increases expression ISO Aconitine results in increased expression of MYH1 protein CTD PMID:33236894 NCBI chr11:67,090,922...67,115,401
Ensembl chr11:67,090,878...67,115,401 		JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta increases expression ISO Aconitine results in increased expression of MYH7 protein CTD PMID:33236894 NCBI chr14:55,208,141...55,232,083
Ensembl chr14:55,208,141...55,232,083 		JBrowse link
G Myl4 myosin, light polypeptide 4 decreases expression ISO Aconitine results in decreased expression of MYL4 protein CTD PMID:33236894 NCBI chr11:104,427,604...104,478,041
Ensembl chr11:104,441,489...104,486,579 		JBrowse link
G Naa35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit increases expression ISO Aconitine results in increased expression of NAA35 protein CTD PMID:33236894 NCBI chr13:59,733,147...59,782,612
Ensembl chr13:59,733,073...59,783,736 		JBrowse link
G Naga N-acetyl galactosaminidase, alpha decreases expression ISO Aconitine results in decreased expression of NAGA protein CTD PMID:33236894 NCBI chr15:82,213,746...82,222,983
Ensembl chr15:82,213,733...82,223,126 		JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D increases expression ISO Aconitine results in increased expression of NAPEPLD protein CTD PMID:33236894 NCBI chr 5:21,867,899...21,906,620
Ensembl chr 5:21,867,899...21,906,394 		JBrowse link
G Ndrg1 N-myc downstream regulated gene 1 increases expression ISO Aconitine results in increased expression of NDRG1 protein CTD PMID:33236894 NCBI chr15:66,801,167...66,841,490
Ensembl chr15:66,801,167...66,841,489 		JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 increases expression ISO Aconitine results in increased expression of NDUFAB1 protein CTD PMID:33236894 NCBI chr 7:121,686,038...121,701,071
Ensembl chr 7:121,684,626...121,701,109 		JBrowse link
G Ndufaf5 NADH:ubiquinone oxidoreductase complex assembly factor 5 increases expression ISO Aconitine results in increased expression of NDUFAF5 protein CTD PMID:33236894 NCBI chr 2:140,012,504...140,047,172
Ensembl chr 2:140,012,569...140,045,609 		JBrowse link
G Ndufaf7 NADH:ubiquinone oxidoreductase complex assembly factor 7 increases expression ISO Aconitine results in increased expression of NDUFAF7 protein CTD PMID:33236894 NCBI chr17:79,244,535...79,255,481
Ensembl chr17:79,244,565...79,255,481 		JBrowse link
G Nek9 NIMA (never in mitosis gene a)-related expressed kinase 9 increases expression ISO Aconitine results in increased expression of NEK9 protein CTD PMID:33236894 NCBI chr12:85,346,288...85,386,136
Ensembl chr12:85,346,288...85,386,136 		JBrowse link
G Niban2 niban apoptosis regulator 2 increases expression ISO Aconitine results in increased expression of NIBAN2 protein CTD PMID:33236894 NCBI chr 2:32,766,146...32,815,265
Ensembl chr 2:32,766,126...32,815,266 		JBrowse link
G Nit2 nitrilase family, member 2 decreases expression ISO Aconitine results in decreased expression of NIT2 protein CTD PMID:33236894 NCBI chr16:56,977,028...56,987,695
Ensembl chr16:56,977,028...56,987,704 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression
multiple interactions		 EXP
ISO		 Aconitine results in increased expression of NLRP3 protein
NLRP3 protein affects the reaction [Aconitine results in increased expression of CASP1 protein]; NLRP3 protein affects the reaction [Aconitine results in increased expression of IL18 protein]; NLRP3 protein affects the reaction [Aconitine results in increased expression of IL1B protein]; NOD1 protein affects the reaction [Aconitine results in increased expression of NLRP3 protein]; NOD2 protein affects the reaction [Aconitine results in increased expression of NLRP3 protein]		 CTD PMID:33236894 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 multiple interactions
increases expression		 ISO NOD1 protein affects the reaction [Aconitine results in increased expression of CASP1 protein]; NOD1 protein affects the reaction [Aconitine results in increased expression of IL18 protein]; NOD1 protein affects the reaction [Aconitine results in increased expression of IL1B protein]; NOD1 protein affects the reaction [Aconitine results in increased expression of NLRP3 protein]
Aconitine results in increased expression of NOD1 protein		 CTD PMID:33236894 NCBI chr 6:54,900,927...54,949,655
Ensembl chr 6:54,900,934...54,949,597 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 multiple interactions
increases expression		 ISO NOD2 protein affects the reaction [Aconitine results in increased expression of CASP1 protein]; NOD2 protein affects the reaction [Aconitine results in increased expression of IL18 protein]; NOD2 protein affects the reaction [Aconitine results in increased expression of IL1B protein]; NOD2 protein affects the reaction [Aconitine results in increased expression of NLRP3 protein]
Aconitine results in increased expression of NOD2 protein		 CTD PMID:33236894 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Nop56 NOP56 ribonucleoprotein increases expression ISO Aconitine results in increased expression of NOP56 protein CTD PMID:33236894 NCBI chr 2:130,112,904...130,121,233
Ensembl chr 2:130,116,350...130,121,233 		JBrowse link
G Notch1 notch 1 increases expression
multiple interactions
affects expression		 ISO Aconitine results in increased expression of NOTCH1 protein modified form
Aconitine promotes the reaction [NOTCH1 protein modified form binds to HCN4 promoter]; Aconitine promotes the reaction [NOTCH1 protein modified form binds to KDM5A protein]; crenigacestat affects the reaction [Aconitine affects the expression of NOTCH1 protein]; crenigacestat inhibits the reaction [Aconitine results in increased expression of NOTCH1 protein modified form]
Aconitine affects the reaction [NOTCH1 protein modified form binds to HCN4 promoter]; crenigacestat inhibits the reaction [Aconitine results in increased expression of NOTCH1 protein modified form]
Aconitine results in increased expression of NOTCH1 protein; Aconitine results in increased expression of NOTCH1 protein modified form		 CTD PMID:32234357 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
G Nppa natriuretic peptide type A decreases expression ISO Aconitine results in decreased expression of NPPA protein CTD PMID:33236894 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression ISO Aconitine results in increased expression of NR1I2 mRNA CTD PMID:30303438 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186 		JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 increases expression ISO Aconitine results in increased expression of NUCKS1 protein CTD PMID:33236894 NCBI chr 1:131,838,196...131,864,059
Ensembl chr 1:131,838,272...131,864,059 		JBrowse link
G Nudt2 nudix hydrolase 2 increases expression ISO Aconitine results in increased expression of NUDT2 protein CTD PMID:33236894 NCBI chr 4:41,465,085...41,480,926
Ensembl chr 4:41,465,151...41,480,926 		JBrowse link
G Nudt8 nudix hydrolase 8 decreases expression ISO Aconitine results in decreased expression of NUDT8 protein CTD PMID:33236894 NCBI chr19:4,050,580...4,052,102
Ensembl chr19:4,050,580...4,052,103 		JBrowse link
G Nutf2 nuclear transport factor 2 increases expression ISO Aconitine results in increased expression of NUTF2 protein CTD PMID:33236894 NCBI chr 8:106,587,165...106,607,034
Ensembl chr 8:106,587,212...106,605,962 		JBrowse link
G Ogfod3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 decreases expression ISO Aconitine results in decreased expression of OGFOD3 protein CTD PMID:33236894 NCBI chr11:121,068,419...121,095,474
Ensembl chr11:121,068,417...121,095,537 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase decreases expression ISO Aconitine results in decreased expression of OPA1 protein CTD PMID:33945864 NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702 		JBrowse link
G Osbp oxysterol binding protein increases expression ISO Aconitine results in increased expression of OSBP protein CTD PMID:33236894 NCBI chr19:11,943,208...11,971,478
Ensembl chr19:11,943,305...11,971,476 		JBrowse link
G Otud4 OTU domain containing 4 increases expression ISO Aconitine results in increased expression of OTUD4 protein CTD PMID:33236894 NCBI chr 8:80,366,305...80,404,384
Ensembl chr 8:80,366,247...80,404,353 		JBrowse link
G Oxa1l oxidase assembly 1-like decreases expression ISO Aconitine results in decreased expression of OXA1L protein CTD PMID:33236894 NCBI chr14:54,598,298...54,607,130
Ensembl chr14:54,598,291...54,607,130 		JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 decreases expression ISO Aconitine results in decreased expression of PABPC1 protein CTD PMID:33236894 NCBI chr15:36,595,902...36,609,825
Ensembl chr15:36,595,905...36,609,912 		JBrowse link
G Pabpc4 poly(A) binding protein, cytoplasmic 4 decreases expression ISO Aconitine results in decreased expression of PABPC4 protein CTD PMID:33236894 NCBI chr 4:123,172,722...123,192,718
Ensembl chr 4:123,156,144...123,192,718 		JBrowse link
G Paip1 polyadenylate binding protein-interacting protein 1 decreases expression ISO Aconitine results in decreased expression of PAIP1 protein CTD PMID:33236894 NCBI chr13:119,564,960...119,596,858
Ensembl chr13:119,565,137...119,594,754 		JBrowse link
G Palm paralemmin increases expression ISO Aconitine results in increased expression of PALM protein CTD PMID:33236894 NCBI chr10:79,629,406...79,656,749
Ensembl chr10:79,629,406...79,656,730 		JBrowse link
G Parl presenilin associated, rhomboid-like decreases expression ISO Aconitine results in decreased expression of PARL protein CTD PMID:33236894 NCBI chr16:20,098,570...20,121,090
Ensembl chr16:20,098,568...20,121,137 		JBrowse link
G Parm1 prostate androgen-regulated mucin-like protein 1 decreases expression ISO Aconitine results in decreased expression of PARM1 protein CTD PMID:33236894 NCBI chr 5:91,665,559...91,771,870
Ensembl chr 5:91,665,474...91,774,753 		JBrowse link
G Parp12 poly (ADP-ribose) polymerase family, member 12 decreases expression ISO Aconitine results in decreased expression of PARP12 protein CTD PMID:33236894 NCBI chr 6:39,063,346...39,095,283
Ensembl chr 6:39,063,344...39,095,283 		JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 decreases expression ISO Aconitine results in decreased expression of PARP14 protein CTD PMID:33236894 NCBI chr16:35,652,262...35,691,904
Ensembl chr16:35,653,244...35,691,914 		JBrowse link
G Pcbp3 poly(rC) binding protein 3 decreases expression ISO Aconitine results in decreased expression of PCBP3 protein CTD PMID:33236894 NCBI chr10:76,597,688...76,797,951
Ensembl chr10:76,597,691...76,797,721 		JBrowse link
G Pcca propionyl-Coenzyme A carboxylase, alpha polypeptide increases expression ISO Aconitine results in increased expression of PCCA protein CTD PMID:33236894 NCBI chr14:122,721,822...123,127,372
Ensembl chr14:122,771,736...123,128,512 		JBrowse link
G Pcnt pericentrin (kendrin) increases expression ISO Aconitine results in increased expression of PCNT protein CTD PMID:33236894 NCBI chr10:76,187,098...76,279,988
Ensembl chr10:76,187,097...76,278,620 		JBrowse link
G Pcyox1 prenylcysteine oxidase 1 increases expression ISO Aconitine results in increased expression of PCYOX1 protein CTD PMID:33236894 NCBI chr 6:86,362,988...86,374,132
Ensembl chr 6:86,362,988...86,374,136 		JBrowse link
G Pdap1 PDGFA associated protein 1 increases expression ISO Aconitine results in increased expression of PDAP1 protein CTD PMID:33236894 NCBI chr 5:145,065,580...145,076,835
Ensembl chr 5:145,065,579...145,077,048 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 decreases expression ISO Aconitine results in decreased expression of PDK4 protein CTD PMID:33236894 NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309 		JBrowse link
G Pdlim3 PDZ and LIM domain 3 increases expression ISO Aconitine results in increased expression of PDLIM3 protein CTD PMID:33236894 NCBI chr 8:46,338,524...46,372,672
Ensembl chr 8:46,338,498...46,372,585 		JBrowse link
G Pdlim4 PDZ and LIM domain 4 increases expression ISO Aconitine results in increased expression of PDLIM4 protein CTD PMID:33236894 NCBI chr11:53,945,754...53,959,814
Ensembl chr11:53,945,754...53,959,840 		JBrowse link
G Pdlim7 PDZ and LIM domain 7 increases expression ISO Aconitine results in increased expression of PDLIM7 protein CTD PMID:33236894 NCBI chr13:55,645,300...55,661,281
Ensembl chr13:55,643,608...55,661,489 		JBrowse link
G Pds5b PDS5 cohesin associated factor B increases expression ISO Aconitine results in increased expression of PDS5B protein CTD PMID:33236894 NCBI chr 5:150,597,178...150,734,174
Ensembl chr 5:150,597,204...150,734,155 		JBrowse link
G Penk preproenkephalin decreases expression ISO Aconitine results in decreased expression of PENK protein CTD PMID:33236894 NCBI chr 4:4,133,536...4,138,815
Ensembl chr 4:4,133,531...4,138,819 		JBrowse link
G Pitpnb phosphatidylinositol transfer protein, beta decreases expression ISO Aconitine results in decreased expression of PITPNB protein CTD PMID:33236894 NCBI chr 5:111,478,563...111,536,225
Ensembl chr 5:111,478,629...111,536,225 		JBrowse link
G Plcb4 phospholipase C, beta 4 decreases expression ISO Aconitine results in decreased expression of PLCB4 protein CTD PMID:33236894 NCBI chr 2:135,500,523...135,856,522
Ensembl chr 2:135,500,931...135,856,513 		JBrowse link
G Plin2 perilipin 2 decreases expression ISO Aconitine results in decreased expression of PLIN2 protein CTD PMID:33236894 NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297 		JBrowse link
G Plin4 perilipin 4 decreases expression ISO Aconitine results in decreased expression of PLIN4 protein CTD PMID:33236894 NCBI chr17:56,407,587...56,416,947
Ensembl chr17:56,407,591...56,416,803 		JBrowse link
G Pln phospholamban decreases expression ISO Aconitine results in decreased expression of PLN protein CTD PMID:33236894 NCBI chr10:53,213,782...53,222,095
Ensembl chr10:53,213,763...53,222,083 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 decreases expression ISO Aconitine results in decreased expression of PLOD3 protein CTD PMID:33236894 NCBI chr 5:137,015,873...137,025,500
Ensembl chr 5:137,015,873...137,025,502 		JBrowse link
G Pm20d2 peptidase M20 domain containing 2 increases expression ISO Aconitine results in increased expression of PM20D2 protein CTD PMID:33236894 NCBI chr 4:33,170,309...33,189,732
Ensembl chr 4:33,174,230...33,189,737 		JBrowse link
G Pon2 paraoxonase 2 increases expression ISO Aconitine results in increased expression of PON2 protein CTD PMID:33236894 NCBI chr 6:5,264,620...5,298,408
Ensembl chr 6:5,264,147...5,298,455 		JBrowse link
G Ppm1b protein phosphatase 1B, magnesium dependent, beta isoform increases expression ISO Aconitine results in increased expression of PPM1B protein CTD PMID:33236894 NCBI chr17:85,264,169...85,331,420
Ensembl chr17:85,264,169...85,331,419 		JBrowse link
G Ppp1r13l protein phosphatase 1, regulatory subunit 13 like increases expression ISO Aconitine results in increased expression of PPP1R13L protein CTD PMID:33236894 NCBI chr 7:19,093,639...19,112,465
Ensembl chr 7:19,093,674...19,112,458 		JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta increases expression ISO Aconitine results in increased expression of PPP2R2B protein CTD PMID:33236894 NCBI chr18:42,777,811...43,192,827
Ensembl chr18:42,770,497...43,216,192 		JBrowse link
G Ppp2r5d protein phosphatase 2, regulatory subunit B', delta decreases expression ISO Aconitine results in decreased expression of PPP2R5D protein CTD PMID:33236894 NCBI chr17:46,993,917...47,015,952
Ensembl chr17:46,993,917...47,016,037 		JBrowse link
G Prpf31 pre-mRNA processing factor 31 increases expression ISO Aconitine results in increased expression of PRPF31 protein CTD PMID:33236894 NCBI chr 7:3,632,984...3,645,484
Ensembl chr 7:3,632,984...3,645,485 		JBrowse link
G Prpf4 pre-mRNA processing factor 4 increases expression ISO Aconitine results in increased expression of PRPF4 protein CTD PMID:33236894 NCBI chr 4:62,327,002...62,345,227
Ensembl chr 4:62,327,034...62,345,227 		JBrowse link
G Psmd12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 decreases expression ISO Aconitine results in decreased expression of PSMD12 protein CTD PMID:33236894 NCBI chr11:107,370,354...107,388,862
Ensembl chr11:107,370,310...107,395,188 		JBrowse link
G Psmd7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 decreases expression ISO Aconitine results in decreased expression of PSMD7 protein CTD PMID:33236894 NCBI chr 8:108,307,012...108,315,114
Ensembl chr 8:108,307,013...108,315,096 		JBrowse link
G Pspc1 paraspeckle protein 1 decreases expression ISO Aconitine results in decreased expression of PSPC1 protein CTD PMID:33236894 NCBI chr14:56,959,898...57,015,775
Ensembl chr14:56,958,167...57,015,773 		JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 increases expression ISO Aconitine results in increased expression of PTBP1 protein CTD PMID:33236894 NCBI chr10:79,690,502...79,700,269
Ensembl chr10:79,690,261...79,700,605 		JBrowse link
G Ptrh2 peptidyl-tRNA hydrolase 2 decreases expression ISO Aconitine results in decreased expression of PTRH2 protein CTD PMID:33236894 NCBI chr11:86,574,900...86,583,283
Ensembl chr11:86,574,811...86,583,283 		JBrowse link
G Pxdn peroxidasin increases expression ISO Aconitine results in increased expression of PXDN protein CTD PMID:33236894 NCBI chr12:29,986,641...30,067,657
Ensembl chr12:29,987,607...30,067,657 		JBrowse link
G Pxmp2 peroxisomal membrane protein 2 decreases expression ISO Aconitine results in decreased expression of PXMP2 protein CTD PMID:33236894 NCBI chr 5:110,422,152...110,434,036
Ensembl chr 5:110,422,148...110,434,052 		JBrowse link
G Pyroxd2 pyridine nucleotide-disulphide oxidoreductase domain 2 decreases expression ISO Aconitine results in decreased expression of PYROXD2 protein CTD PMID:33236894 NCBI chr19:42,714,296...42,741,261
Ensembl chr19:42,714,297...42,741,214 		JBrowse link
G Pyurf Pigy upstream reading frame increases expression ISO Aconitine results in increased expression of PYURF protein CTD PMID:33236894 NCBI chr 6:57,661,724...57,669,063
Ensembl chr 6:57,663,561...57,669,063 		JBrowse link
G Qdpr quinoid dihydropteridine reductase decreases expression ISO Aconitine results in decreased expression of QDPR protein CTD PMID:33236894 NCBI chr 5:45,591,374...45,607,571
Ensembl chr 5:45,591,363...45,607,578 		JBrowse link
G Rab10 RAB10, member RAS oncogene family decreases expression ISO Aconitine results in decreased expression of RAB10 protein CTD PMID:33236894 NCBI chr12:3,297,428...3,359,969
Ensembl chr12:3,297,428...3,359,969 		JBrowse link
G Rab35 RAB35, member RAS oncogene family increases expression ISO Aconitine results in increased expression of RAB35 protein CTD PMID:33236894 NCBI chr 5:115,769,953...115,785,217
Ensembl chr 5:115,769,967...115,785,795 		JBrowse link
G Rabgap1l RAB GTPase activating protein 1-like decreases expression ISO Aconitine results in decreased expression of RABGAP1L protein CTD PMID:33236894 NCBI chr 1:160,046,744...160,621,046
Ensembl chr 1:160,046,744...160,620,781 		JBrowse link
G Rabl6 RAB, member RAS oncogene family-like 6 increases expression ISO Aconitine results in increased expression of RABL6 protein CTD PMID:33236894 NCBI chr 2:25,473,029...25,498,493
Ensembl chr 2:25,473,030...25,498,533 		JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 multiple interactions ISO Aconitine analog inhibits the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]] CTD PMID:16862215 NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596 		JBrowse link
G Ralb v-ral simian leukemia viral oncogene B increases expression ISO Aconitine results in increased expression of RALB protein CTD PMID:33236894 NCBI chr 1:119,398,035...119,432,512
Ensembl chr 1:119,398,035...119,432,524 		JBrowse link
G Raly hnRNP-associated with lethal yellow decreases expression ISO Aconitine results in decreased expression of RALY protein CTD PMID:33236894 NCBI chr 2:154,632,989...154,712,930
Ensembl chr 2:154,633,016...154,709,181 		JBrowse link
G Ran RAN, member RAS oncogene family decreases expression ISO Aconitine results in decreased expression of RAN protein CTD PMID:33236894 NCBI chr 5:129,097,264...129,101,388
Ensembl chr 5:129,097,133...129,101,387 		JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO Aconitine analog inhibits the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]] CTD PMID:16862215 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Rbm3 RNA binding motif (RNP1, RRM) protein 3 decreases expression ISO Aconitine results in decreased expression of RBM3 protein CTD PMID:33236894 NCBI chr  X:8,005,214...8,012,119
Ensembl chr  X:8,005,214...8,012,119 		JBrowse link
G Rbp4 retinol binding protein 4, plasma increases expression ISO Aconitine results in increased expression of RBP4 protein CTD PMID:33236894 NCBI chr19:38,105,068...38,113,769
Ensembl chr19:38,105,077...38,113,729 		JBrowse link
G Rbpms RNA binding protein gene with multiple splicing increases expression ISO Aconitine results in increased expression of RBPMS protein CTD PMID:33236894 NCBI chr 8:34,272,671...34,419,925
Ensembl chr 8:34,272,671...34,419,891 		JBrowse link
G Rcn1 reticulocalbin 1 decreases expression ISO Aconitine results in decreased expression of RCN1 protein CTD PMID:33236894 NCBI chr 2:105,216,293...105,229,664
Ensembl chr 2:105,216,636...105,229,664 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) increases expression ISO Aconitine results in increased expression of RELA protein CTD PMID:33236894 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Rheb Ras homolog enriched in brain increases expression ISO Aconitine results in increased expression of RHEB protein CTD PMID:33236894 NCBI chr 5:25,007,821...25,047,359
Ensembl chr 5:25,007,821...25,047,622 		JBrowse link
G Rigi RNA sensor RIG-I decreases expression ISO Aconitine results in decreased expression of RIGI protein CTD PMID:33236894 NCBI chr 4:40,203,775...40,239,843
Ensembl chr 4:40,203,773...40,239,828 		JBrowse link
G Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 increases expression ISO
EXP		 Aconitine results in increased expression of RIPK2 protein CTD PMID:33236894 NCBI chr 4:16,122,740...16,163,674
Ensembl chr 4:16,122,733...16,163,647 		JBrowse link
G Rmdn1 regulator of microtubule dynamics 1 decreases expression ISO Aconitine results in decreased expression of RMDN1 protein CTD PMID:33236894 NCBI chr 4:19,575,036...19,606,932
Ensembl chr 4:19,575,162...19,606,932 		JBrowse link
G Rnf213 ring finger protein 213 decreases expression ISO Aconitine results in decreased expression of RNF213 protein CTD PMID:33236894 NCBI chr11:119,280,778...119,378,245
Ensembl chr11:119,283,926...119,378,244 		JBrowse link
G Rnf7 ring finger protein 7 increases expression ISO Aconitine results in increased expression of RNF7 protein CTD PMID:33236894 NCBI chr 9:96,352,990...96,360,728
Ensembl chr 9:96,352,990...96,360,728 		JBrowse link
G Rpa3 replication protein A3 decreases expression ISO Aconitine results in decreased expression of RPA3 protein CTD PMID:33236894 NCBI chr 6:8,255,936...8,259,141
Ensembl chr 6:8,255,936...8,259,173 		JBrowse link
G Rpl36 ribosomal protein L36 increases expression ISO Aconitine results in increased expression of RPL36 protein CTD PMID:33236894 NCBI chr17:56,917,094...56,921,246
Ensembl chr17:56,920,416...56,921,243 		JBrowse link
G Rpl7 ribosomal protein L7 decreases expression ISO Aconitine results in decreased expression of RPL7 protein CTD PMID:33236894 NCBI chr 1:16,171,519...16,174,657
Ensembl chr 1:16,171,519...16,174,886 		JBrowse link
G Rplp1 ribosomal protein lateral stalk subunit P1 decreases expression ISO Aconitine results in decreased expression of RPLP1 protein CTD PMID:33236894 NCBI chr 9:61,820,565...61,821,792
Ensembl chr 9:61,820,566...61,821,824 		JBrowse link
G Rpn2 ribophorin II decreases expression ISO Aconitine results in decreased expression of RPN2 protein CTD PMID:33236894 NCBI chr 2:157,121,018...157,168,238
Ensembl chr 2:157,120,937...157,168,239 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 increases expression ISO Aconitine results in increased expression of RPS6KB1 mRNA CTD PMID:28099878 NCBI chr11:86,389,695...86,435,711
Ensembl chr11:86,389,697...86,435,631 		JBrowse link
G Rras related RAS viral (r-ras) oncogene increases expression ISO Aconitine results in increased expression of RRAS protein CTD PMID:33236894 NCBI chr 7:44,665,686...44,671,070
Ensembl chr 7:44,667,385...44,671,071 		JBrowse link
G Rwdd1 RWD domain containing 1 decreases expression ISO Aconitine results in decreased expression of RWDD1 protein CTD PMID:33236894 NCBI chr10:33,872,551...33,895,612
Ensembl chr10:33,872,551...33,895,620 		JBrowse link
G S100a9 S100 calcium binding protein A9 (calgranulin B) increases expression ISO Aconitine results in increased expression of S100A9 protein CTD PMID:33236894 NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028 		JBrowse link
G S100b S100 protein, beta polypeptide, neural multiple interactions
increases expression		 EXP ABCB1A gene mutant form promotes the reaction [Aconitine results in increased expression of S100B protein] CTD PMID:28193520 NCBI chr10:76,089,670...76,097,153
Ensembl chr10:76,089,687...76,096,993 		JBrowse link
G Sars1 seryl-tRNA synthetase 1 decreases expression ISO Aconitine results in decreased expression of SARS1 protein CTD PMID:33236894 NCBI chr 3:108,332,180...108,352,575
Ensembl chr 3:108,332,181...108,352,525 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression ISO Aconitine results in decreased expression of SCARB1 mRNA CTD PMID:31499053 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158 		JBrowse link
G Scpep1 serine carboxypeptidase 1 decreases expression ISO Aconitine results in decreased expression of SCPEP1 protein CTD PMID:33236894 NCBI chr11:88,814,846...88,846,268
Ensembl chr11:88,814,846...88,846,291 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 increases expression ISO Aconitine results in increased expression of SDF2L1 protein CTD PMID:33236894 NCBI chr16:16,948,002...16,950,247
Ensembl chr16:16,948,002...16,950,247 		JBrowse link
G Sec61a1 SEC61 translocon subunit alpha 1 decreases expression ISO Aconitine results in decreased expression of SEC61A1 protein CTD PMID:33236894 NCBI chr 6:88,480,589...88,495,782
Ensembl chr 6:88,480,561...88,495,887 		JBrowse link
G Secisbp2l SECIS binding protein 2-like increases expression ISO Aconitine results in increased expression of SECISBP2L protein CTD PMID:33236894 NCBI chr 2:125,578,906...125,624,790
Ensembl chr 2:125,578,906...125,624,790 		JBrowse link
G Sema3c sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C increases expression ISO Aconitine results in increased expression of SEMA3C protein CTD PMID:33236894 NCBI chr 5:17,779,814...17,935,266
Ensembl chr 5:17,779,279...17,935,266 		JBrowse link
G Sephs1 selenophosphate synthetase 1 increases expression ISO Aconitine results in increased expression of SEPHS1 protein CTD PMID:33236894 NCBI chr 2:4,886,375...4,915,368
Ensembl chr 2:4,886,375...4,915,368 		JBrowse link
G Septin11 septin 11 decreases expression ISO Aconitine results in decreased expression of SEPTIN11 protein CTD PMID:33236894 NCBI chr 5:93,227,445...93,329,237
Ensembl chr 5:93,241,296...93,324,306 		JBrowse link
G Septin4 septin 4 decreases expression ISO Aconitine results in decreased expression of SEPTIN4 protein CTD PMID:33236894 NCBI chr11:87,457,515...87,481,365
Ensembl chr11:87,457,479...87,481,365 		JBrowse link
G Serpina6 serine (or cysteine) peptidase inhibitor, clade A, member 6 decreases expression ISO Aconitine results in decreased expression of SERPINA6 protein CTD PMID:33236894 NCBI chr12:103,612,889...103,623,477
Ensembl chr12:103,612,889...103,623,471 		JBrowse link
G Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1 decreases expression ISO Aconitine results in decreased expression of SERPINF1 protein CTD PMID:33236894 NCBI chr11:75,300,855...75,313,449
Ensembl chr11:75,300,595...75,313,527 		JBrowse link
G Sf3a1 splicing factor 3a, subunit 1 increases expression ISO Aconitine results in increased expression of SF3A1 protein CTD PMID:33236894 NCBI chr11:4,110,354...4,132,541
Ensembl chr11:4,110,350...4,132,541 		JBrowse link
G Sh2b1 SH2B adaptor protein 1 increases expression ISO Aconitine results in increased expression of SH2B1 protein CTD PMID:33236894 NCBI chr 7:126,066,165...126,075,882
Ensembl chr 7:126,066,166...126,074,596 		JBrowse link
G Sirt2 sirtuin 2 increases expression ISO Aconitine results in increased expression of SIRT2 protein CTD PMID:33236894 NCBI chr 7:28,466,192...28,488,086
Ensembl chr 7:28,466,160...28,488,086 		JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Aconitine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375 		JBrowse link
G Slc25a19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 decreases expression ISO Aconitine results in decreased expression of SLC25A19 protein CTD PMID:33236894 NCBI chr11:115,504,991...115,519,122
Ensembl chr11:115,505,004...115,519,121 		JBrowse link
G Slc25a20 solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 increases expression
decreases expression		 ISO Aconitine results in increased expression of SLC25A20 protein
Aconitine results in decreased expression of SLC25A20 protein		 CTD PMID:33236894 NCBI chr 9:108,539,335...108,561,841
Ensembl chr 9:108,539,287...108,561,840 		JBrowse link
G Slc28a2 solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 decreases expression ISO Aconitine results in decreased expression of SLC28A2 protein CTD PMID:33236894 NCBI chr 2:122,256,836...122,291,633
Ensembl chr 2:122,256,958...122,291,618 		JBrowse link
G Slc33a1 solute carrier family 33 (acetyl-CoA transporter), member 1 decreases expression ISO Aconitine results in decreased expression of SLC33A1 protein CTD PMID:33236894 NCBI chr 3:63,849,744...63,872,154
Ensembl chr 3:63,840,928...63,872,189 		JBrowse link
G Slc4a1 solute carrier family 4 (anion exchanger), member 1 increases expression ISO Aconitine results in increased expression of SLC4A1 protein CTD PMID:33236894 NCBI chr11:102,239,646...102,256,107
Ensembl chr11:102,239,650...102,257,029 		JBrowse link
G Smpx small muscle protein, X-linked increases expression ISO Aconitine results in increased expression of SMPX protein CTD PMID:33236894 NCBI chr  X:156,481,969...156,535,587
Ensembl chr  X:156,481,906...156,535,587 		JBrowse link
G Smyd5 SET and MYND domain containing 5 increases expression ISO Aconitine results in increased expression of SMYD5 protein CTD PMID:33236894 NCBI chr 6:85,408,958...85,423,411
Ensembl chr 6:85,408,971...85,423,417 		JBrowse link
G Sptan1 spectrin alpha, non-erythrocytic 1 increases expression ISO Aconitine results in increased expression of SPTAN1 protein CTD PMID:33236894 NCBI chr 2:29,855,572...29,921,463
Ensembl chr 2:29,855,572...29,921,463 		JBrowse link
G Srp68 signal recognition particle 68 increases expression ISO Aconitine results in increased expression of SRP68 protein CTD PMID:33236894 NCBI chr11:116,135,992...116,165,043
Ensembl chr11:116,135,992...116,165,043 		JBrowse link
G Srsf6 serine and arginine-rich splicing factor 6 increases expression ISO Aconitine results in increased expression of SRSF6 protein CTD PMID:33236894 NCBI chr 2:162,773,428...162,779,041
Ensembl chr 2:162,773,448...162,779,041 		JBrowse link
G Ssbp1 single-stranded DNA binding protein 1 increases expression ISO Aconitine results in increased expression of SSBP1 protein CTD PMID:33236894 NCBI chr 6:40,448,302...40,458,757
Ensembl chr 6:40,448,286...40,461,634 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression ISO Aconitine results in decreased expression of STAT1 protein CTD PMID:33236894 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stat2 signal transducer and activator of transcription 2 decreases expression ISO Aconitine results in decreased expression of STAT2 protein CTD PMID:33236894 NCBI chr10:128,106,367...128,128,722
Ensembl chr10:128,106,428...128,128,718 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 increases expression ISO Aconitine results in increased expression of STAT4 protein CTD PMID:33236894 NCBI chr 1:52,026,265...52,146,348
Ensembl chr 1:52,026,307...52,146,348 		JBrowse link
G Stx12 syntaxin 12 increases expression ISO Aconitine results in increased expression of STX12 protein CTD PMID:33236894 NCBI chr 4:132,581,375...132,611,769
Ensembl chr 4:132,580,812...132,611,820 		JBrowse link
G Stxbp1 syntaxin binding protein 1 decreases expression ISO Aconitine results in decreased expression of STXBP1 protein CTD PMID:33236894 NCBI chr 2:32,677,619...32,737,249
Ensembl chr 2:32,677,614...32,737,257 		JBrowse link
G Syngr2 synaptogyrin 2 decreases expression ISO Aconitine results in decreased expression of SYNGR2 protein CTD PMID:33236894 NCBI chr11:117,700,459...117,705,112
Ensembl chr11:117,700,494...117,705,109 		JBrowse link
G Tardbp TAR DNA binding protein decreases expression ISO Aconitine results in decreased expression of TARDBP protein CTD PMID:33236894 NCBI chr 4:148,696,839...148,711,672
Ensembl chr 4:148,696,839...148,711,476 		JBrowse link
G Tax1bp3 Tax1 (human T cell leukemia virus type I) binding protein 3 increases expression ISO Aconitine results in increased expression of TAX1BP3 protein CTD PMID:33236894 NCBI chr11:73,067,909...73,072,872
Ensembl chr11:73,067,909...73,073,988 		JBrowse link
G Tbc1d5 TBC1 domain family, member 5 decreases expression ISO Aconitine results in decreased expression of TBC1D5 protein CTD PMID:33236894 NCBI chr17:51,040,155...51,488,228
Ensembl chr17:51,040,152...51,486,380 		JBrowse link
G Tfam transcription factor A, mitochondrial increases expression ISO Aconitine results in increased expression of TFAM protein CTD PMID:33945864 NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110 		JBrowse link
G Tfrc transferrin receptor decreases expression ISO Aconitine results in decreased expression of TFRC protein CTD PMID:33236894 NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612 		JBrowse link
G Tgoln1 trans-golgi network protein increases expression ISO Aconitine results in increased expression of TGOLN2 protein CTD PMID:33236894 NCBI chr 6:72,585,403...72,593,983
Ensembl chr 6:72,585,415...72,593,983 		JBrowse link
G Thbd thrombomodulin increases expression ISO Aconitine results in increased expression of THBD protein CTD PMID:33236894 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108 		JBrowse link
G Thrap3 thyroid hormone receptor associated protein 3 decreases expression ISO Aconitine results in decreased expression of THRAP3 protein CTD PMID:33236894 NCBI chr 4:126,057,875...126,096,548
Ensembl chr 4:126,057,875...126,096,553 		JBrowse link
G Timm29 translocase of inner mitochondrial membrane 29 increases expression ISO Aconitine results in increased expression of TIMM29 protein CTD PMID:33236894 NCBI chr 9:21,504,018...21,507,266
Ensembl chr 9:21,504,018...21,507,266 		JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 decreases expression ISO Aconitine results in decreased expression of TM9SF2 protein CTD PMID:33236894 NCBI chr14:122,342,290...122,397,015
Ensembl chr14:122,344,450...122,397,016 		JBrowse link
G Tmed4 transmembrane p24 trafficking protein 4 decreases expression ISO Aconitine results in decreased expression of TMED4 protein CTD PMID:33236894 NCBI chr11:6,220,714...6,224,837
Ensembl chr11:6,220,369...6,224,870 		JBrowse link
G Tmem126a transmembrane protein 126A decreases expression ISO Aconitine results in decreased expression of TMEM126A protein CTD PMID:33236894 NCBI chr 7:90,099,908...90,106,411
Ensembl chr 7:90,099,908...90,106,437 		JBrowse link
G Tmem167 transmembrane protein 167 decreases expression ISO Aconitine results in decreased expression of TMEM167A protein CTD PMID:33236894 NCBI chr13:90,237,843...90,263,047
Ensembl chr13:90,237,242...90,292,026 		JBrowse link
G Tmem182 transmembrane protein 182 decreases expression ISO Aconitine results in decreased expression of TMEM182 protein CTD PMID:33236894 NCBI chr 1:40,844,738...40,896,047
Ensembl chr 1:40,844,761...40,896,047 		JBrowse link
G Tmem186 transmembrane protein 186 decreases expression ISO Aconitine results in decreased expression of TMEM186 protein CTD PMID:33236894 NCBI chr16:8,451,595...8,455,575
Ensembl chr16:8,451,093...8,455,576 		JBrowse link
G Tmem38a transmembrane protein 38A decreases expression ISO Aconitine results in decreased expression of TMEM38A protein CTD PMID:33236894 NCBI chr 8:73,325,033...73,341,128
Ensembl chr 8:73,325,899...73,341,126 		JBrowse link
G Tmem65 transmembrane protein 65 decreases expression ISO Aconitine results in decreased expression of TMEM65 protein CTD PMID:33236894 NCBI chr15:58,654,118...58,695,510
Ensembl chr15:58,654,118...58,695,487 		JBrowse link
G Tmod4 tropomodulin 4 increases expression ISO Aconitine results in increased expression of TMOD4 protein CTD PMID:33236894 NCBI chr 3:95,030,110...95,036,520
Ensembl chr 3:95,031,787...95,036,520 		JBrowse link
G Tmpo thymopoietin increases expression ISO Aconitine results in increased expression of TMPO protein CTD PMID:33236894 NCBI chr10:90,983,433...91,017,614
Ensembl chr10:90,983,433...91,017,177 		JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 increases expression ISO Aconitine results in increased expression of TMX1 protein CTD PMID:33236894 NCBI chr12:70,499,928...70,514,398
Ensembl chr12:70,499,869...70,514,814 		JBrowse link
G Tnrc6b trinucleotide repeat containing 6b increases expression ISO Aconitine results in increased expression of TNRC6B protein CTD PMID:33236894 NCBI chr15:80,595,514...80,825,287
Ensembl chr15:80,595,514...80,825,286 		JBrowse link
G Tomm22 translocase of outer mitochondrial membrane 22 decreases expression ISO Aconitine results in decreased expression of TOMM22 protein CTD PMID:33236894 NCBI chr15:79,555,069...79,557,063
Ensembl chr15:79,555,062...79,557,601 		JBrowse link
G Tpmt thiopurine methyltransferase decreases expression ISO Aconitine results in decreased expression of TPMT protein CTD PMID:33236894 NCBI chr13:47,175,463...47,196,833
Ensembl chr13:47,175,958...47,198,213 		JBrowse link
G Trak1 trafficking protein, kinesin binding 1 decreases expression ISO Aconitine results in decreased expression of TRAK1 protein CTD PMID:33236894 NCBI chr 9:121,126,568...121,303,985
Ensembl chr 9:121,126,568...121,303,984 		JBrowse link
G Trappc3 trafficking protein particle complex 3 decreases expression ISO Aconitine results in decreased expression of TRAPPC3 protein CTD PMID:33236894 NCBI chr 4:126,156,198...126,169,676
Ensembl chr 4:126,156,118...126,169,676 		JBrowse link
G Trappc4 trafficking protein particle complex 4 decreases expression ISO Aconitine results in decreased expression of TRAPPC4 protein CTD PMID:33236894 NCBI chr 9:44,315,057...44,318,629
Ensembl chr 9:44,314,995...44,318,897 		JBrowse link
G Trim21 tripartite motif-containing 21 increases expression ISO Aconitine results in increased expression of TRIM21 protein CTD PMID:33236894 NCBI chr 7:102,207,127...102,214,689
Ensembl chr 7:102,207,128...102,214,693 		JBrowse link
G Trim25 tripartite motif-containing 25 decreases expression ISO Aconitine results in decreased expression of TRIM25 protein CTD PMID:33236894 NCBI chr11:88,890,194...88,911,119
Ensembl chr11:88,890,202...88,911,119 		JBrowse link
G Trp53 transformation related protein 53 increases expression ISO Aconitine results in increased expression of TP53 protein CTD PMID:24840785 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions ISO TRPA1 results in increased susceptibility to [Vehicle Emissions co-treated with Aconitine] CTD PMID:21377951 NCBI chr 1:14,942,868...14,989,086
Ensembl chr 1:14,942,872...14,989,086 		JBrowse link
G Tsn translin increases expression ISO Aconitine results in increased expression of TSN protein CTD PMID:33236894 NCBI chr 1:118,226,244...118,239,463
Ensembl chr 1:118,222,508...118,239,469 		JBrowse link
G Ttc39b tetratricopeptide repeat domain 39B decreases expression ISO Aconitine results in decreased expression of TTC39B protein CTD PMID:33236894 NCBI chr 4:83,138,537...83,242,488
Ensembl chr 4:83,138,537...83,242,492 		JBrowse link
G Ttr transthyretin increases expression ISO Aconitine results in increased expression of TTR protein CTD PMID:33236894 NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378 		JBrowse link
G Tuba4a tubulin, alpha 4A decreases expression ISO Aconitine results in decreased expression of TUBA4A protein CTD PMID:33236894 NCBI chr 1:75,190,867...75,197,905
Ensembl chr 1:75,190,872...75,196,509 		JBrowse link
G Txnip thioredoxin interacting protein decreases expression ISO Aconitine results in decreased expression of TXNIP protein CTD PMID:33236894 NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199 		JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats increases expression ISO Aconitine results in increased expression of UACA protein CTD PMID:33236894 NCBI chr 9:60,700,488...60,787,713
Ensembl chr 9:60,701,824...60,787,652 		JBrowse link
G Uba2 ubiquitin-like modifier activating enzyme 2 decreases expression ISO Aconitine results in decreased expression of UBA2 protein CTD PMID:33236894 NCBI chr 7:33,840,121...33,868,014
Ensembl chr 7:33,840,113...33,869,024 		JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 decreases expression ISO Aconitine results in decreased expression of UBE2D3 protein CTD PMID:33236894 NCBI chr 3:135,143,993...135,173,975
Ensembl chr 3:135,143,910...135,173,959 		JBrowse link
G Ube2f ubiquitin-conjugating enzyme E2F (putative) increases expression ISO Aconitine results in increased expression of UBE2F protein CTD PMID:33236894 NCBI chr 1:91,177,412...91,214,243
Ensembl chr 1:91,178,026...91,218,059 		JBrowse link
G Ube3a ubiquitin protein ligase E3A increases expression ISO Aconitine results in increased expression of UBE3A protein CTD PMID:33236894 NCBI chr 7:58,871,891...58,960,585
Ensembl chr 7:58,878,498...58,961,284 		JBrowse link
G Ubl5 ubiquitin-like 5 increases expression ISO Aconitine results in increased expression of UBL5 protein CTD PMID:33236894 NCBI chr 9:20,554,013...20,558,436
Ensembl chr 9:20,554,174...20,558,436 		JBrowse link
G Ubqln2 ubiquilin 2 increases expression ISO Aconitine results in increased expression of UBQLN2 protein CTD PMID:33236894 NCBI chr  X:152,281,228...152,284,558
Ensembl chr  X:152,281,223...152,284,566 		JBrowse link
G Ufl1 UFM1 specific ligase 1 decreases expression ISO Aconitine results in decreased expression of UFL1 protein CTD PMID:33236894 NCBI chr 4:25,247,149...25,281,821
Ensembl chr 4:25,248,600...25,281,821 		JBrowse link
G Ufm1 ubiquitin-fold modifier 1 decreases expression ISO Aconitine results in decreased expression of UFM1 protein CTD PMID:33236894 NCBI chr 3:53,760,797...53,771,228
Ensembl chr 3:53,760,797...53,771,251 		JBrowse link
G Unc45a unc-45 myosin chaperone A increases expression ISO Aconitine results in increased expression of UNC45A protein CTD PMID:33236894 NCBI chr 7:79,975,040...79,990,748
Ensembl chr 7:79,975,040...79,997,741 		JBrowse link
G Upp1 uridine phosphorylase 1 decreases expression ISO Aconitine results in decreased expression of UPP1 protein CTD PMID:33236894 NCBI chr11:9,068,008...9,086,170
Ensembl chr11:9,068,103...9,086,170 		JBrowse link
G Uqcc1 ubiquinol-cytochrome c reductase complex assembly factor 1 decreases expression ISO Aconitine results in decreased expression of UQCC1 protein CTD PMID:33236894 NCBI chr 2:155,688,806...155,772,230
Ensembl chr 2:155,688,814...155,772,230 		JBrowse link
G Uqcr10 ubiquinol-cytochrome c reductase, complex III subunit X decreases expression ISO Aconitine results in decreased expression of UQCR10 protein CTD PMID:33236894 NCBI chr11:4,651,968...4,654,344
Ensembl chr11:4,651,973...4,654,342 		JBrowse link
G Usp13 ubiquitin specific peptidase 13 (isopeptidase T-3) increases expression ISO Aconitine results in increased expression of USP13 protein CTD PMID:33236894 NCBI chr 3:32,870,432...32,992,224
Ensembl chr 3:32,871,695...32,992,220 		JBrowse link
G Usp4 ubiquitin specific peptidase 4 (proto-oncogene) increases expression ISO Aconitine results in increased expression of USP4 protein CTD PMID:33236894 NCBI chr 9:108,223,763...108,269,744
Ensembl chr 9:108,225,052...108,269,744 		JBrowse link
G Usp9x ubiquitin specific peptidase 9, X chromosome increases expression ISO Aconitine results in increased expression of USP9X protein CTD PMID:33236894 NCBI chr  X:12,937,221...13,039,567
Ensembl chr  X:12,937,737...13,039,567 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 increases expression ISO Aconitine results in increased expression of VAMP8 protein CTD PMID:33236894 NCBI chr 6:72,362,204...72,367,650
Ensembl chr 6:72,362,206...72,367,686 		JBrowse link
G Vapb vesicle-associated membrane protein, associated protein B and C increases expression ISO Aconitine results in increased expression of VAPB protein CTD PMID:33236894 NCBI chr 2:173,579,378...173,626,132
Ensembl chr 2:173,579,304...173,626,132 		JBrowse link
G Vbp1 von Hippel-Lindau binding protein 1 increases expression ISO Aconitine results in increased expression of VBP1 protein CTD PMID:33236894 NCBI chr  X:74,557,903...74,578,552
Ensembl chr  X:74,557,905...74,578,548 		JBrowse link
G Vdac2 voltage-dependent anion channel 2 decreases expression ISO Aconitine results in decreased expression of VDAC2 protein CTD PMID:33236894 NCBI chr14:21,881,629...21,895,947
Ensembl chr14:21,875,306...21,895,947 		JBrowse link
G Vdac3 voltage-dependent anion channel 3 decreases expression ISO Aconitine results in decreased expression of VDAC3 protein CTD PMID:33236894 NCBI chr 8:23,067,091...23,083,829
Ensembl chr 8:23,067,102...23,083,774 		JBrowse link
G Vps26c VPS26 endosomal protein sorting factor C decreases expression ISO Aconitine results in decreased expression of VPS26C protein CTD PMID:33236894 NCBI chr16:94,298,583...94,327,488
Ensembl chr16:94,298,642...94,327,689 		JBrowse link
G Vps37c vacuolar protein sorting 37C increases expression ISO Aconitine results in increased expression of VPS37C protein CTD PMID:33236894 NCBI chr19:10,666,095...10,691,992
Ensembl chr19:10,666,099...10,691,991 		JBrowse link
G Wdr37 WD repeat domain 37 increases expression ISO Aconitine results in increased expression of WDR37 protein CTD PMID:33236894 NCBI chr13:8,853,002...8,922,136
Ensembl chr13:8,853,004...8,921,945 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein decreases expression ISO Aconitine results in decreased expression of WFS1 protein CTD PMID:33236894 NCBI chr 5:37,123,448...37,146,326
Ensembl chr 5:37,123,448...37,146,549 		JBrowse link
G Xpo1 exportin 1 decreases expression ISO Aconitine results in decreased expression of XPO1 protein CTD PMID:33236894 NCBI chr11:23,205,768...23,248,250
Ensembl chr11:23,206,055...23,248,249 		JBrowse link
G Yap1 yes-associated protein 1 increases expression ISO Aconitine results in increased expression of YAP1 protein CTD PMID:33236894 NCBI chr 9:7,932,000...8,004,890
Ensembl chr 9:7,932,000...8,004,597 		JBrowse link
G Zdbf2 zinc finger, DBF-type containing 2 increases expression ISO Aconitine results in increased expression of ZDBF2 protein CTD PMID:33236894 NCBI chr 1:63,239,517...63,353,735
Ensembl chr 1:63,312,424...63,353,735 		JBrowse link
G Zfp207 zinc finger protein 207 increases expression ISO Aconitine results in increased expression of ZFP207 protein CTD PMID:33236894 NCBI chr11:80,274,105...80,299,387
Ensembl chr11:80,274,105...80,296,559 		JBrowse link
G Zfp692 zinc finger protein 692 increases expression ISO Aconitine results in increased expression of ZFP692 protein CTD PMID:33236894 NCBI chr11:58,197,883...58,205,971
Ensembl chr11:58,197,895...58,205,453 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22308
    chemical entity 22307
      atom 22302
        nonmetal atom 22132
          carbon atom 21924
            organic molecular entity 21924
              isoprenoid 14780
                terpenoid 14475
                  diterpenoid 13719
                    aconitine 459
                      aconifine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22308
    subatomic particle 22302
      composite particle 22302
        hadron 22302
          baryon 22302
            nucleon 22302
              atomic nucleus 22302
                atom 22302
                  main group element atom 22183
                    main group molecular entity 22183
                      s-block molecular entity 21773
                        hydrogen molecular entity 21687
                          hydrides 20792
                            organic hydride 20337
                              organic fundamental parent 20337
                                hydrocarbon 19917
                                  terpene 14780
                                    terpenoid 14475
                                      diterpenoid 13719
                                        diterpene alkaloid 511
                                          aconitane 500
                                            aconitine 459
                                              aconifine 0
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