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Gene: Serpinf1 (serine (or cysteine) peptidase inhibitor, clade F, member 1) Mus musculus
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Symbol: Serpinf1
Name: serine (or cysteine) peptidase inhibitor, clade F, member 1
RGD ID: 1332124
Description: Predicted to have serine-type endopeptidase inhibitor activity. Involved in negative regulation of angiogenesis and negative regulation of epithelial cell proliferation involved in prostate gland development. Localizes to extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Used to study osteogenesis imperfecta type 6. Human ortholog(s) of this gene implicated in several diseases, including bone disease (multiple); brain edema; eye disease (multiple); leukostasis; and non-alcoholic steatohepatitis. Orthologous to human SERPINF1 (serpin family F member 1); INTERACTS WITH (S)-nicotine; 1,1-dichloroethene; 1,2-dichloroethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI195227; alpha-2 antiplasmin; caspin; EPC-; EPC-1; Ped; Pedf; Pedfl; pigment epithelium derived factor; pigment epithelium-derived factor; pigment epithelium-derived factor-like; Sdf; SDF-3; Sdf3; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serine (or cysteine) proteinase inhibitor, clade F), member 1; serine (or cysteine) proteinase inhibitor, clade F, member 1; serpin F1; serpin-F1; stromal cell derived factor 3; stromal cell-derived factor 3
Orthologs:
Homo sapiens (human) : SERPINF1 (serpin family F member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Serpinf1 (serpin family F member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpinf1 (serpin family F member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINF1 (serpin family F member 1)
Canis lupus familiaris (dog) : SERPINF1 (serpin family F member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpinf1 (serpin family F member 1)
Sus scrofa (pig) : SERPINF1 (serpin family F member 1)
Chlorocebus sabaeus (African green monkey) : SERPINF1 (serpin family F member 1)
Heterocephalus glaber (naked mole-rat) : Serpinf1 (serpin family F member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,300,855 - 75,313,449 (-)NCBI
GRCm381175,410,029 - 75,422,623 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,409,769 - 75,422,701 (-)EnsemblGRCm38mm10GRCm38
MGSCv371175,223,531 - 75,236,125 (-)NCBIGRCm37mm9NCBIm37
MGSCv361175,225,964 - 75,238,707 (-)NCBImm8
Celera1182,918,458 - 82,931,037 (-)NCBICelera
Cytogenetic Map11B5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Serpinf1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1332124
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2020-11-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.